LILLY, Malcolm Douglas v1

LILLY_MALCOLM_DOUGLAS_v1

Catalogue of the papers and correspondence of Malcolm Douglas Lilly FEng FRS (1936-1998) NCUACS catalogue no.150/7/06 By Peter Harper and Timothy E. Powell M.D. Lilly NCUACS 150/7/06 Title: Compiled by: Peter Harper and Timothy E. Powell Catalogue of the papers and correspondence of Malcolm Douglas Lilly (1936- 1998) FEng FRS, biochemical engineer NCUACS catalogue no. 150/7/06 © 2006 National Cataloguing Unit for the Archives of Contemporary Scientists, University of Bath Special Collections, Library, University College London Reference code: GB 0103 M_D. Lilly Date of material: 1957-2003 Extent of material: ca 2,000 items Deposited in: Lilly M.D. NCUACS 150/7/06 NOT ALL THE MATERIAL IN THIS COLLECTION MAY YET BE AVAILABLE FOR CONSULTATION. ENQUIRIES SHOULD BE ADDRESSED IN THE FIRST INSTANCE TO: HEAD OF SPECIAL COLLECTIONDS AND ARCHIVIST SPECIAL COLLECTIONS LIBRARY SERVICES UNIVERSITY COLLEGE LONDON M.D. Lilly NCUACS 150/7/06 The work of the National Cataloguing Unit for the Archives of Contemporary Scientists in the production of this catalogue is made possible by the support of the following societies and organisations: Biochemical Society Institute of Physics Trinity College Cambridge University College London Royal Society Royal Society of Chemistry Wellcome Trust M.D. Lilly NCUACS 150/7/06 LIST OF CONTENTS GENERAL INTRODUCTION SECTION A BIOGRAPHICAL A.1-A.15 SECTION B NOTEBOOKS AND RESEARCH NOTES B.1-B.46 SECTION C UNIVERSITY COLLEGE LONDON C.1-C.971 SECTION D PUBLICATIONS SECTION E LECTURES D.1-D.366 E.1-E.69 SECTION F SOCIETIES AND ORGANISATIONS paler One GH-Grl57 SECTION H SECTION J H.1-H.76 J.1-J.22 SECTION G CONSULTANCIES CORRESPONDENCE VISITS AND CONFERENCES INDEX OF CORRESPONDENTS M.D. Lilly NCUACS 150/7/06 GENERAL INTRODUCTION PROVENANCE The papers were received from Mrs Sheila Lilly, widow, in June 2004 and September 2005. OUTLINE OF THE CAREER OF MALCOLM DOUGLAS LILLY Malcolm Douglas Lilly was born on 9 August 1936. He grew up in Eltham in South London and was educated at St Olave’s and St Saviour’s Grammar School and, after a period of national service in the Royal Navy, University College London where he read biochemistry and went on to research on microbial enzymes in the research group of the Patricia H. Clarke, working with Pauline Meadow (PhD 1962). Lilly then transferred to the Department of Chemical Engineering to work on immobilised enzymes with Eric Crook (NCUACS catalogue 147/4/06). In 1963 he was appointed Lecturer in Biochemical Engineering, joined a few years later by Peter Dunnill who became his closest collaborator. One of the key areas of their research ‘was the development of methods for using the high specificity of enzymes for complex reactions that were difficult to carry out by standard chemical methods. biological fuel cells’. Obituary by Patricia H. Clarke, Guardian, 18 June 1998. In 1964 properties during purification and large-scale operations. It was also essential to develop appropriate importance. Immobilised enzymes have increased stability and can be used in commercial they improved the design of the fermenters in which the micro-organisms were grown. Malcolm's milk homogenisers used by the dairy industry could be used for disrupting micro-organisms. Later enzyme for the production of semi-synthetic penicillins. He researched biotransformation throughout equipment. ... [They] investigated equipment already used in industry. For example, they found that Because biological molecules, such as enzymes, are not as stable as industrial chemicals, basic his career, but also worked on other topics including mammalian cell culture, nucleotide isolation and research was needed to find out the best methods for maintaining their structure, and catalytic bioreactors for longer periods. One of the early successes at UCL was using an immobilised bacterial early work on the properties of enzymes immobilised by attachment to resin beads had particular national centre by the Science and Engineering Research Council (SERC) in 1987, the start of the a Biochemical Engineering Section was established within the Department of Chemical Engineering Lilly's career was closely connected to the development of biochemical engineering at UCL. and in 1966 the University of London approved the establishment of an MSc, with an undergraduate degree following in 1973. In 1979 Lilly was appointed the first Professor of Biochemical Engineering in the country. Further recognition for biochemical engineering at UCL came with its recognition as a M.D. Lilly NCUACS 150/7/06 construction of an Advanced Centre for Biochemical Engineering in 1990 and in 1991 the establishment there of the UK Interdisciplinary Research Centre (IRC) in Biochemical Engineering supported by the SERC. Peter Dunnill was Director and Lilly, Chairman. The final step in a long struggle for the academic recognition was achieved in 1998 with the establishment of a separate Department of Biochemical Engineering as part of the School of Process Engineering. Outside UCL Lilly was active in supporting biochemical engineering nationally and internationally. In 1981 when the Science and Engineering Research Council set up a Biotechnology Directorate under Dr Geoffrey Potter to encourage research in the field, Lilly (and others from UCL) served on the Biotechnology Management Committee. He was involved in several new international organisations including the International Organisation for Biotechnology and Bioengineering (Chairman 1972-1980) and the European Federation of Biotechnology. With colleagues from the Polytechnic of Central London (now University of Westminster) and the University of Kent he set up the Institute for Biotechnology Studies (later International Institute of Biotechnology), to promote multidisciplinary developments in biotechnology research and teaching. He was a member of the Board of Management and Executive Committee, 1983-1989. Other public responsibilities that he undertook included membership of the Research Board of British Gas, 1982-1994 and membership of the Board of the Public Health Laboratory Service, 1988-1994. he was able to continue research until the last days of his life. He died on 18 May 1998. For further information on the life and work of Lilly see ‘Malcolm Douglas Lilly 9 August 1936 - 18 May biochemical engineer to receive both awards. He was a visiting Professor at the University of Pennsylvania in 1969 and a Visiting Research Fellow at Merck, USA in 1987. His outstanding achievement in biochemical engineering was widely recognised. In 1976 he was Engineering, the first non-American to receive the award. He was elected to the Fellowship of struck by cancer, which he fought courageously for more than ten years. With the support of his wife awarded the Food, Pharmaceutical and Bioengineering Award of the American Institute of Chemical In 1959 he married Sheila Stuart with whom he had two sons. At the height of his powers he was Engineering (now Royal Academy of Engineering) in 1982 and of the Royal Society in 1991, the first (2000). 1998’ by Patricia H. Clarke, Biographical Memoirs of Fellows of the Royal Society, vol.46, pp 317-332 M.D. Lilly NCUACS 150/7/06 DESCRIPTION OF THE COLLECTION The collection is presented as given in the list of contents. It is dominated by extensive documentation of the development of biochemical engineering at University College London and covers the period 1957-2003. Section A, Biographical, is slight but includes a copy of the obituary that appeared in the Guardian newspaper, curriculum vitae, bibliography, list of theses supervised and an interesting record of his lengthy efforts to secure membership of the Institution of Chemical Engineers. Section B, Notebooks and research notes, includes a sequence of notebooks covering an extended period, 1962-1998, in a variety of formats and used for a variety of purposes, including address book, lists of things to do, notes of meetings with UCL colleagues, European Federation of Biotechnology meetings, bibliographical references, etc. A notebook used from ‘11/10/1997’ is identified as ‘MDL’s last notebook’. In addition there are research notes covering the period, 1965-1997. Some identifiable groups of notes have titles such as ‘Control Systems’, ‘Fermentation’ and ‘Progesterone Conversion’ but many notes were found loose and in no order and are undated. at UCL in an ‘Advanced Centre’, 1986-1995. some overlap with material in ‘ACBE’ files. The Research grants subsection presents and Miscellaneous. The ‘History’ subsection comprises the contents of folders and box folders The IRC subsection documents developments Section C, University College London, is by far the largest component of the archive. It documents labelled ‘history’ or ‘historical’ and includes strategic papers and records of developments in teaching, research and facilities. The ACBE subsection includes correspondence and papers relating to the key aspects of the development of biochemical engineering there and covers the period, 1957-2002. It is subdivided into seven subsections: ‘History’, Advanced Centre for Biochemical Engineering associated with UCL becoming in 1991 the research council funded IRC for Biochemical Engineering creation of purpose-designed facilities for training and research activities in biochemical engineering (ACBE), Interdisciplinary Research Centre (IRC), Research grants, Teaching and training, Personnel with a ten year remit to develop an interdisciplinary programme of research and teaching. There is Personnel subsection relates principally to research students and visitors to the Department and at UCL by Lilly and colleagues. The material is further organised by funding body or programme, by training subsection presents Lilly's ‘teaching notes’ covering a variety of courses for UCL students and others and substantial documentation for biochemical engineering summer courses given at UCL for participants from industry and academe, many from overseas. The dating of the ‘teaching notes’ correspondence and papers about funding of research and related matters in biochemical engineering is often problematic. The summer courses are fully documented from no.3 to no.15, 1979-1991. The research contract client and by research topic and under the heading ‘Patents’. The Teaching and M.D. Lilly NCUACS 150/7/06 documents arrangements to visit, research, publications and later contacts with the Department. The contents of the Miscellaneous subsection is very diverse including equipment and facilities, research programmes, joint project with Biotechnology Computer Systems Ltd, collaboration with Tel Aviv University and correspondence with UCL Provost, Sir James Lighthill. Section D, Publications, presents a near comprehensive record of Lilly's own scientific papers, 1962- 2003, including a number of posthumous publications. The documentation may include manuscript and typescript drafts, correspondence and offprints. Also included here are the contents of a folder of ‘unpublished’ drafts. Publications correspondence is not extensive but there is some material relating to the journals with which Lilly was associated as author, reviewer and editor. Section E, Lectures, provides documentation of Lilly’s public and invitation lectures, 1966-1996. Topics include ‘Immobilised Enzyme Reactors’, ‘Developments in Biocatalysis’, 'Two-liquid phase biocatalytic reactors’, ‘Industrial Use of Biocatalysts for Asymmetric Synthesis’ and ‘Biochemical Engineering - Its Contribution to Society’, Lilly's 1988 Sir Harold Hartley Memorial Lecture. There are also many untitled lecture notes and drafts and some illustrative material for lectures and papers. the G, Section Consultancies, twenty-one commercial organisations, 1968-1997, including Beckman Instruments Inc, Beecham Group Ltd / Smith Kline Beecham and Merck Sharp & Dohme Research Laboratories. On occasions Lilly consulted in documents consultancy relationships with 1968-1998. organisations, Amongst the best documented are Section F, Societies and organisations, documents Lilly's association with twenty-four British and international European Commission, whose programmes supported biochemical engineering developments at the European level, and the European Federation of Biotechnology (EFB) and the International Organisation for Biotechnology and Bioengineering (IOBB), both of which Lilly served in a number of capacities including for the OBB a period as chairman. Lilly's papers include a ‘Formation of the EFB’ file. The most comprehensively documented body is the Institute for Biotechnology Studies / International Institute of Biotechnology, including correspondence and papers relating to the formation of the Institute, trustees and management committee meetings, research programme, policy review, etc. on proceedings. At the end of the chronological sequence are papers relating to a number of meetings that Lilly was unable to attend because of ill health. The documentation may include programmes, lists of participants, abstracts and Lilly's notes Section H, Visits and conferences, covers the period 1964-1998. partnership with his UCL colleague Peter Dunnill as Biotech Consultants. M.D. Lilly NCUACS 150/7/06 Section J, Correspondence, is slight. There is a sequence of correspondence presented chronologically, 1966-1998, made up of letters found loose and without context. There are also references and recommendations, 1968-1998. There is also an index of correspondents. ACKNOWLEDGEMENTS We are very grateful to Mrs Sheila Lilly for making the papers available for cataloguing and to Mrs Lilly and Professor John Woodley for information and advice. LOCATION OF OTHER MATERIAL Correspondence and papers relating to the preparation of the Royal Society biographical memoir of Lilly form part of the archive of Professor Patricia Clarke catalogued for University College London Library Special Collections (NCUACS catalogue no. 120/6/03). M.D. Lilly NCUACS 150/7/06 SECTION A BIOGRAPHICAL, A.1-A.15 1962-2000 Announcement of death from UCL website Obituary, Guardian, 18 June 1998 Curriculum vitae October 1990 Bibliography of 236 publications 1962-2000 2000 List of theses supervised by Lilly 1966-1994 ‘Excited by enzymes’ Short account by Lilly Spring 1994 of his research in SERC bulletin, of Nucleotides and _ outstanding achievement in the field Title page only of Lilly’s PhD thesis, April 1962 Food, American Institute of Chemical Engineers Pharmaceutical and ‘Accumulation Extracellular Lipoproteins by Lysine Dependent Mutants of Escherichia Coll’ Nomination papers for Lilly's candidature for New Scientist Award of for technology 1964-1980 Correspondence and papers re efforts of Lilly membership of the Institution. His definitive election as a Member of the Institution was only confirmed in a He was transferred to the class of personal chair at UCL. 1979, the year of his election to Institution of Chemical Engineers membership, 1979 Manuscript notes for Lilly’s acceptance speech. Bioengineering to secure Award, M.D. Lilly NCUACS 150/7/06 Biographical, A.1-A.15 Fellow in 1980. 1964-1977 1978-1980 N.d. Includes ‘Biochemical Engineering Aspects of Enzyme Technology. Lilly submitted to the Institution of Chemical Engineers’. synopsis research M.D. by of A Election to Fellowship of the Royal Society Typescript draft friends and colleagues to mark his election. of remarks by Lilly at a gathering of From A.13-A.15 Antibiotics: Acceptance ‘Post-penicillin Portrait photograph of Lilly Lilly was unable to attend and died on 18 May 1998. ‘Knowledge Acquisition and Implementation of a Prototype for an Expert System to Design Biochemical Reactors’ Typescript notes etc for Wellcome Trust Witness Seminar on to Resistance’, 12 May 1998 At A.13 is a letter of thanks from Sinclair to Lilly. M.Sc Project by J.T. Sinclair. of the project and is the ‘expert’ referred to in the text. Lilly was interviewed as part Two folders and bound volume. M.D. Lilly NCUACS 150/7/06 SECTION B NOTEBOOKS AND RESEARCH NOTES, B.1-B.46 1962-1998 B.1-B.34 NOTEBOOKS B.35-B.46 RESEARCH NOTES NOTEBOOKS 1962-1998, n.d. These notebooks are in serve a number of purposes. a great variety of formats and The catalogue entries incorporate identifications by Mrs Sheila Lilly. Hardback notebook used for ‘Senior / Chief Technician’s notes by Paddy Legge’ 1962-1963 Notes are dated, 31 December 1962 - 6 December 1963. is enclosed at ‘Research Notes Penicillin amidase’ 1964-1966 An undated note from ‘Paddy’ to ‘Dr Lilly’ the front of the notebook. Hardback notebook so labelled on front cover used for experimental record, ‘19th May’ [1964] - ‘29/10/66’. Some undated notes towards the end of the notebook. The project is outlined in a note inside front cover. Northfleet / Gravesend [Kent] in 1964’. Small format softback notebook used for research notes, notes headed ‘Flowering Shrubs’, etc. Notebook used for ‘MDL’s first list of papers ... game / ref. for Bill Hornby/ ... to classes in Gravesend 1963 onwards’ a word ‘ and ‘Russian when we went / Latest bibliographical reference 1965. ‘Flowering shrubs were being bought for our first home at M.D. Lilly NCUACS 150/7/06 Notebooks and research notes, B.1-B.46 Small format notebook, very mixed in content, used for notes and chapter headings of book with ?Peter Dunnill, research notes including, from the back, work with P.H. Clarke, etc. Latest bibliographical reference 1966. Small format hardback notebook used for lists of things to do 1970-1971 Entries run from 2 June 1970. Small format hardback notebook used from the front for list of publications and from the back for lists of things to do, also notes of Society of Chemical Industry meeting, etc, 1972-1973 Small format meetings, etc. hardback notebook used for notes of Mrs Lilly identified the meeting at Rouen with which the notebook begins as dating from 1972. See E.4. B.10-B.14 Five same format softback exercise books used for notes re work of research students front covers identifying Small format notebook used for lists of things to do and at the back for list of publications. 1974-1975 1977-1979 Notebooks have labels on the research students though in the case of B.14 the name has been crossed out. Hardback notebook used by Lilly for record of ? incoming correspondence and action taken The label for B.10 also identifies the topic ‘Cholesterol Oxidase’. Entries run from ‘2.1.74’. Used for first half of the year only. M.D. Lilly NCUACS 150/7/06 Notebooks and research notes, B.1-B.46 Small publications at front and miscellaneous notes at back notebook hardback format used for list of Pearly 1980s Probably in use early 1980s. Reference to Banff [Alberta, Canada] may be to 1981 meeting there. See H.23-H.25. format hardback notebook used to ?The Institute for of for Biotechnology record Small. meetings relating Studies 1982-1983 See also F.166-F.271. Small format hardback notebook used for lists of things to do, etc. 1983-1985 Notebook (covers missing) used for notes on meetings, etc. 1985-1986 Includes Society of Chemical Industry meeting, 19 June 1986. used for notes on European ?late 1980s 1985-1987 Lilly's research student Probably in use late 1980s. Large format notebook used by R.C. Eglin Hardback Federation of Biotechnology (EFB) meetings, etc. notebook 1990-1992 Hardback notebook used for notes for meetings with UCL colleagues re research, building, equipment, IRC, Link, etc. Small format hardback notebook used for lists of things to do, etc. Hardback notebook used for notes of meetings with UCL colleagues re research, etc. [1989]-1990 1989-1991 M.D. Lilly NCUACS 150/7/06 Notebooks and research notes, B.1-B.46 For IRC see C.152-C.194. For Link programme see B.26, C.941. B.27, C.236-C.304, C.930- Small hardback notebook used for lists of things to do, etc. 1991-1992 Small format hardback notebook used for bibliographical references from the front and from the back for notes re Link programme. c.1993 - 1994 A4 size hardback notebook used for notes on meetings with fermentation research, transketolase, IRC strategy, Link etc. colleagues: meeting, training UCL 1993-1997 A4 size softback notebook: includes notes on ‘Meeting on Labview 17/6/94’ backed. Exercise’ = Book: ...Used:: for “Qin. xe. 7... Binder used for bibliographical references Soft. bibliographical references Small format hardback notebook identified as ‘WDL’s last notebook from 11/10/1997’ 1997-1998 Address book with manuscript note ‘This seems to cover almost the whole of MDL’s research period at UCL’ Hardback notebook used for bibliographical references Softback notebook used for bibliographical references Loose items enclosed. M.D. Lilly NCUACS 150/7/06 Notebooks and research notes, B.1-B.46 B.35-B.46 RESEARCH NOTES 1965-1997 B.35-B.36 ‘VI. Control Systems’ Contents of folder so inscribed divided into two for ease of reference: background material, latest publication date 1964. manuscript printed draft and ‘Active (incomplete but not active)’ Projects’, ‘Projects completed’ and ‘Projects Papers so titled found clipped together. The papers seem to form a record of the research situation in December 1970. ‘4 Phase Fermentations’ Contents of folder so inscribed: manuscript and typescript notes, background printed papers. Latest bibliographical reference in the notes, 1972. B.39-B.40 ‘Fermentation’ Contents of folder so inscribed divided into two for ease of reference: manuscript list of bibliographical references, offprints, etc. At B.40 are ‘Tables and figures Topic No.1 Growth and Metabolism Fermentation Technology’ by C.L. Cooney, Massachusetts Institute of Technology, 30 July - 3 August 1973. 1968-1978 Contents of folder so inscribed: manuscript and typescript notes, correspondence, etc. Contents of folder so inscribed: mansucript data and plots. is possible that the contents are more diverse than the It folder title suggests. ‘Progesterone Conversion’ ‘1000 Litre Data’ M.D. Lilly NCUACS 150/7/06 Notebooks and research notes, B.1-B.46 B.43-B.46 Shorter notes and drafts found loose and in no order. 1965-1997 Many papers undated. Four folders. Lilly M.D. NCUACS 150/7/06 SECTION C UNIVERSITY COLLEGE LONDON, C.1-C.971 1957-2002 section This aspects development of Biochemical Engineering at UCL. documents significant of the Important dates include: 1954 Joint research undertaken between the Departments of Biochemistry and Chemical Engineering. 1958 Guinness lecturer (Dr F. Webb) appointed. 1964 Biochemical Engineering Section established. 1976 Biochemical Engineering’. Departmental name changed to ‘Chemical and Recognised as a national centre by Science and 1987 Engineering Research Council (SERC). 1990 Construction of Advanced Centre started. Interdisciplinary Research Centre (IRC) supported 1991 by SERC. - as part of the School of 1973 BEng (3 year) started. 1966 MSc approved by University. Teaching courses developed as follows: 1959 Postgraduate Diploma Course (1year). 1977 Annual one-week post-experience course started. 1998 Formation of two Departments - the Department of Biochemical Engineering and Department of Chemical Engineering Process Engineering. RESEARCH GRANTS ADVANCED CENTRE FOR BIOCHEMICAL ENGINEERING (ACBE) INTERDISCIPLINARY RESEARCH CENTRE (IRC) The material is arranged as follows: C.1-C.40 ‘HISTORY’ C.41-C.151 C.152-C.194 C.195-C.472 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.473-C.757 TEACHING AND TRAINING C.758-C.891 PERSONNEL C.892-C.971 MISCELLANEOUS ‘HISTORY’ 1957-1998 Contents of folders and box folders labelled ‘history’ ‘historical’. or ‘UCL Historical’ 1957-1989 Contents of folder so inscribed. 1957-1966 N.d. Research’ in [21963] manuscript Engineering prospects of Biochemical manuscript draft with Papers found clipped to the preceding: future ‘The University College’ typescript 8pp additions and corrections. and ‘Project Reports for Period ist Sept. 1965 - 31st Aug. 1966’, 4pp typescript. ‘Biochemical Engineering Equipment’, 3pp typescript + 1p typescript headed ‘Dr Crook’s original draft’. 1970-1972 University Engineering Department Syllabus of the 1 year Postgraduate Course in Biochemical Engineering, 1p duplicated typescript, n.d. ‘Biochemical Engineering Education and M.C. Reece, The Industrial Chemist, July 1957. with manuscript underscoring. Correspondence and papers by Off-print Includes ‘Supplementary Report to the Enzyme and College London Chemical M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Technology Committee’ by Lilly and P.Dunnill. Correspondence and papers Principally re research and funding. 1983-1989 of Lists membership and consultancies [Lilly's] research grants, committee and panel The lists were prepared after 1989. Manuscript engineering at UCL and typescript drafts re biochemical Includes ‘Future Developments in Biochemical Engineering at UCL A Discussion Paper’, + ‘Appendix II Biochemical Engineering Personnel’. 12pp manuscript draft on the present state and of See also C.38. 1p typescript 25 November 1963. Architect’s drawings for UCL Engineering Faculty ‘Biochemical Engineering Accommodation and Equipment’ ‘Memorandum future biochemical engineering at University College London’ Council’ by Lilly, February 1967. 2pp duplicated typescript memorandum by [?Eric Baldwin], 3 December 1963, enclosing eight documents by M.B. Donald, E.M. Crook, Lilly and others. Includes and Medical Use A Report submitted to the Science Research of Enzymes for Industrial Supply ‘The Correspondence and papers Two folders. ‘EB’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Insolubilised Amyloglucosidase at U.C.L.’ AK tunoocrrint ‘ 4pp typescript ‘Department of Chemical Engineering, University College London Biochemical Engineering Section’ Spp typescript + publications list. reference, 1968. Latest bibliographical Correspondence re projects and funding October 1969 Correspondence and Research Group papers re Enzyme Technology 1970-1973 C.14-C.18 ‘Historical re teaching’ c. 1972-1995 1973-1977 papers re visits of students Many undated papers. Contents of folder so inscribed divided into five for ease of reference: lecture lists, course summaries, timetables etc. Correspondence and to Thames Water Authority Crossness Sewage Treatment Works Correspondence on biotechnology between Lilly and J.M. Ashworth, Chief Scientist, Cabinet Office Central Policy Review Staff 1980-1982 Those taking part in the discussion included Lilly, Peter Dunnill, also of UCL, and Eric Crook of St Bartholomew's Hospital Medical School, formerly of UCL. Correspondence in biochemical engineering and biotechnology at UCL and developments papers ‘Enzymes Chemistry and Industry, 1 April 1978 industrial and _ catalysis discussion’, - a and re M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 nationally. nelidac nany af lattar ta tha Drima Himwsiuucse vLUpy Vi ITO W UIT FiO Wititiowwi, iat atl vaiiualy £ 1981, about biotechnology in co- signatory) and letter from Lilly to the Provost UCL, 8 March 1982, about ‘plans for the creation of a College Centre for Biochemical Engineering and Technology’. the UK (Lilly was a ‘Dev of SERC Centre’ 1983-1986 folder Contents of inscribed: correspondence and papers re development of UCL as a centre for Biochemical Engineering and related matters. so See also C.952-C.954 Correspondence University Committee additional equipment grant for 1985/86 papers and re _ Grants Centre Foundation in respect of the Biochemical for 1985-1986 UCL Biochemical Engineering Newsletters nos 2 and 3 to Wolfson Application creation Engineering (ACBE) at UCL The Government made available the additional equipment grant ‘for the improvement of laboratory and equipment provision in a few carefully selected centres of research’. The selection committee under Sir Andrew Huxley put forward a list of research groups including that of Lilly and Peter Dunnill. 1989 and n.d. Contents of folder so inscribed divided into three for ease of reference: photographs of equipment and architect's models, and architect's drawings. The drawings are dated August - October 1989. ‘Biochemical Engineering at UCL’ ‘History Engineering] / ACBE [Advanced for Biochemical C.27-C.29 of an Advanced Centre M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 1p handout listing some important dates, teaching courses, academic staff and research areas. Conference des Grandes Ecoles Visit Centre for Biochemical Engineering UCL, 1993 to the Advanced 17 February Contents of folder inscribed ‘history’: correspondence and papers re visit. Opening Engineering, 8 September 1993 Advanced the of Centre for Biochemical Account of the opening in ‘bioBulletin’ the newsletter of the biotechnology directorate SERC, November 1993. ‘Undergraduate paper’ Biochemical Engineering - a position comments of a separate and _ Biochemical Department UCL Engineering Strategic Plan 1997-2000 Chemical Correspondence and papers re formation of UCL Department of Biochemical Engineering Copy of position paper ?by Nigel Titchenor-Hooker, with Lilly’s on _— undergraduate biochemical engineering, 25 November 1995. = manuscript 1997-1998 ‘Chemical Essential Points made by Department in support of claim for an Increased Recurrent Grant’ 3pp typescript + ‘Comparison of Departmental Resources with Other Departments represented on the Working ‘The future of biochemical engineering at UCL’ Summary of its 3pp typescript. Incomplete. & Biochemical Engineering . Party’. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Architect's drawing oa See also L.D. eer C.39, C.40 Printed papers re biochemical engineering at UCL and more generally. 1984 and n.d. Two folders. C.41-C.151 ADVANCED ENGINEERING (ACBE) CENTRE FOR BIOCHEMICAL 1983-1997 of box ring folders, binders, Contents entitled ‘Advanced Centre for Biochemical Engineering’ or ‘ACBE’: correspondence and the creation and research activities in biochemical engineering at UCL in an ‘Advanced council assessment, 1996-1997. of purpose-designed facilities to training 1986-1995 principally research Centre’, papers, relating and etc for include UCL, included Provosts biochemical See also C.26, C.27-C.29, C.32. Correspondents engineering colleagues, architects, funders, etc. The contents of a number of boxes and folders were found in considerable disorder much undated material, the assignment of which is tentative. Include drawings and plans, minutes of meetings and much photocopied material, notes, drafts, etc sent to Lilly by UCL biochemical engineering colleagues. 1986-1989 ‘Advanced Engineering Preliminary Architectural, Engineering & Costing Study’ The Engineering Limited. In original binder. ‘A.C.B.E A-L’ Biochemical Contents of April 1986 C.42-C.50 binder so inscribed prepared Matthew divided by titled study was Hall Norcain Centre for A and by ring M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 subject dividers. A eithiagct Aivtidar : MPA SUNjJCUL UIVIUC! | any surviving papers. Correspondence with industrial and commercial concerns relates to fund raising and research cooperation. Miscellaneous papers at front of binder including list of ‘Contacts [in respect of fund raising] made up to mid-June 1987’ 1986-1987 ‘ACBE Appeal’ ‘Alfa-Laval’ 1986-1987 1986-1989 Engineering Alfa-Laval equipment manufacturer in respect of fermentation and bioprocessing technology. was an _ Ltd 1986-1987 1986-1988 ‘Archaeology Appeal’ Lilly was a member of the Sub-Committee. ‘Architects’ Sub-Committee (architect, general)’ Lilly was a member of the Executive Appeal Committee for the Archaeological Conservation Centre. 1988-1990 1986-1988 ‘British Gas’ ‘Bayer’ One letter only. ‘Beechams’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Davy McKee’ ‘General correspondence, etc.’ One letter only. of letter Carbon the Biotechnology Unit of the Laboratory of the Government Chemist. Coleman from Lilly R. to of ‘Gist-Brocades’ ‘Glaxo’ ‘Wensley Haydon-Baillie’ ‘ICI’ 1987-1988 1987 1988 1986, 1988 ring binder so inscribed not N.d. C.51-C.63 divided by titled 1984-1989 Leverhulme Trust ‘ACBE M-Z2’ One letter only. Contents of subject dividers. A subject divider inscribed ‘Tel-Aviv University’ did correspond to any Surviving papers. Correspondence with industrial and commercial concerns relates to fund raising and research cooperation. Includes cost estimates for the ACBE. Copies of correspondence between Provost UCL and Wolfson Foundation found loose at front of binder Matthew Hall / Stearns Catalytic’ Marks & Spencer M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Merck’ ‘Porton International’ One letter only. ‘Project Sub-Committee’ 1986-1987 Lilly was a member of Proposed Development of the Gordon Street Site. Project Sub-Committee - the ‘Sainsbury’ ‘Sasakawa Foundation’ ‘Unilever’ up feasibility strategy the for financing ‘Smith, Kline & French’ Thomas Harris & Associates Re drawing development. ‘UGC [University Grants Committee]’ 1986 Two folders. ‘Wellcome’ ‘Wolfson’ 1984-1988 1986-1988 1986, 1988 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘The Creation of an Advanced Centre for Biochemical Engineering’ 11pp typescript + appendices. Bound volume ‘Conceptual for Biochemical Engineering’ Study the Advanced Centre for April 1988 Prepared by Davy McKee ‘A Davy Corporation Company’. In original binder. C.65-C.66 Contents of untitled ring binder divided into two for ease of reference 1989-1990 Includes manuscript notes and drawings by Lilly. 1) MDLilly C.69-C.73 five for ease of In original binder. Prepared by Davy McKee. See also C.68. ‘Report of Design Requirements’, February ‘Comments on DMK Document (Revision 25/2/90’ 2pp manuscript notes found at the front of the Report at C.67. ‘client technical brief’ Letter from Davy McKee, 20 March 1990, enclosing a set of documents, principally drawings ‘at preliminary status only’. Contents of untitled binder divided into reference Contents of binder so inscribed: ‘Technical Package’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 prepared by Davy McKee, August 1990. original binder. Retained in See also C.75. Papers found loose at the front of ‘Technical Package’ binder C.76-C.143 General correspondence and papers 1985-1997 C.76 1985 C78-C.79 1987 Two folders. Four folders Twelve folders. C.80-C.83 1988 C.84-C.94A 1989 Undated papers tentatively assigned to 1988 are at C.83. Eight folders. C.103-C.113 1991 C.95-C.102 1990 Eleven folders M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.114-C.116 1992 Three foiders. C.117-C.122 1993 Six folders. C.117 includes papers for Robinson, Chief Advisor on Science and Technology, Department of Trade and Industry to UCL, 14 January 1993. visit G. of C.144-C.151 1983-1990 on AIO Two folders. C.143 are C4276 143 N.d. Sixteen folders. for presentation C.126-C.141 transparencies At biochemical engineering at UCL and the ACBE. Eight folders. Engineers’ drawings M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.152-C.194 INTERDISCIPLINARY RESEARCH CENTRE (IRC) 1989-1997 box ‘IRC’: Contents of correspondence and papers re establishment, programme and assesment of the IRC. inscribed folders, folders, etc There is some overlap with materials found in ‘ACBE’ folders. The assignment of undated papers is tentative. In 1991 UCL became the IRC for Biochemical Engineering (Director Peter Dunnill) with a ten year remit to develop an interdisciplinary programme of research and teaching. In 1995, following a review of the IRC the Biotechnology and Biological it should be ‘converted to a 4-year funding cycle, with the budget being set using the Council’s funding formula for institutes’. The Centre was assessed in 1996 and received a Visiting Group in 1997. Sciences Research Council decided that 1989 1990 1991 1992 Five folders. C.153-C.157 Eight folders. C.166-C.175 C.158-C.165 Includes much undated material found in great disorder. C.177-C.181 Ten folders. 1994 Five folders. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.182, C.183 1995 Two folders. C.185-C.189 1997 Five folders. C.190-C.194 N.d. Five folders. C.195-C.472 RESEARCH GRANTS 1962-1998 C.195-C.387 C.388-C.401 C.460-C.472 Patents C.402-C.459 By research topic Grants’: in of Lilly's boxes labelled ‘Research By research contract client By funding body or programme The material is presented as follows: Contents correspondence and papers re funding of research, etc biochemical engineering at UCL by Lilly and colleagues. Council By funding body and programme Alphabetical sequence Biotechnology and Biological Sciences Research 1992-1997 C.195-C.387 1962-1998 C.195-C.201 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.195-C.197 ‘Project with Warwick’ 1994-1995 and nten reference: correspondence so inscribed divided into three for ease of grant proposal entitled ‘Large-scale Biotransformation for the Recycling of Industrial By-Products of Speciality Chemical Manufacture’. was made under the ‘Cleaner Synthesis for Industry’ initiative and submitted by D.H.G. Crout and P.Critchley of the University of Warwick and Lilly and J.M. Woodley of UCL. This grant proposal papers re ‘Clean Technology’ 1992, 1994 folder Contents of papers re Research Councils’ interest research towards new clean technologies. inscribed: correspondence and in promotion of so ? relates to ‘Project with Warwick’ (C.195-C.197). ‘BBSRC’ of folder so re Lilly inscribed: correspondence ‘1998 PhD Proposal’ Drafts for application. Contents research studentships. ‘TK [transketolase] application’ Contents of folder so inscribed: papers re application by J.M. Ward, J.M. Woodley and titled ‘Recombinant transketolase with broad industrial potential’. 1983-1985 Contents of folder inscribed ‘DTI’ divided into six for ease of reference: principally research reports. Department of Trade and Industry See also Link Programme. C.202-C.207 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.208, C.209 Engineering and Physical Sciences Research Council (EPSRC) 1995-1996 Contents of folder inscribed ‘Polyleucines Exeter [crossed out] (Roberts) divided into two for ease of reference: application and related papers. The project was titled ‘Scale up of asymmetric epoxidation reactions the investigators were S.M. Roberts (Liverpool), Lilly and J.M. Woodley. polyleucine catalysts’ based using and C.210-C.235 European Commission (EC) C.210-C.217 ‘Biochemical engineering programme’ 1979-1998 1979-1985 folder so Community Contents of folder so inscribed divided into eight for ease of reference: correspondence and papers re proposal for a European and development in biochemical engineering and specific UCL research proposal within the framework of the programme on ‘the development of multiphase bio-reactors for the modification of oils and fats. programme research for 1994-1995 C.219-C.234 ‘FP4 Proposal’ ‘Research Grant (Last one he worked on) FP4 - Proposal BVMO [Baeyer-Villiger Mono-oxegenases]’ Contents of inscribed: correspondence and papers re proposed joint EC project with DSM Research in the Netherlands on two phase liquid biocatalysis. 1996-1997 Contents of folder with post-it note so inscribed divided into sixteen for ease of reference: correspondence and papers re proposal titled ‘Biotransformations using Baeyer-Villiger Mono-oxegenases’. These papers were found in considerable disorder and have been presented in the order found. Project partners came from the UK and France, Germany, Italy, the Netherlands and Switzerland. See also C.235. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘EC Grant Proposal’ Contents manuscript proposal. of folder re notes inscribed: so _ correspondence, Baeyer-Villiger Mono-oxegenases See also C.219-C.234. C.236-C.304 Link Programme 1988-1997 This programme was jointly funded by the Department of Engineering Trade and Research encouraging collaborative university-industrial research projects. Industry and Council with the Science and view the to for ICI to a four relate proposal Biological (accepted) SmithKline engineering - biochemical companies The papers a UCL/Industry consortium involving Beecham Pharmaceuticals, (Zeneca BioProducts), Shell Research and Unilever Research. The objective was to support biochemical engineering research and training at UCL, initially for four years, by providing funds for pre-competitive research, provision of research facilities and assistance with training. The start date was 1 September 1990 with 30 August 1994. a completion date of Products C.236-C.243 a chronological sequence as See also C.930-C.941, F.362-F.367. ‘LINK - Setting Up - 1988/1989’ Much of the material was found in labelled folders which have been used as the basis of arrangement. However, there was also a large number of loose papers which have been presented in far as possible. 1988-1990 Contents of folder so labelled divided into eight for ease of reference: correspondence and papers. Contents of folder so labelled divided into seven for ease of reference: correspondence and papers. ‘LINK - Setting up - 1990’ C.244-C.250 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.251-C.257 ‘LINK Agreement / Offer Letter / RG2 / E14 / Original Proposals etc’ 1989-1994 Contents of folder so labelled divided into seven for ease of reference: correspondence and papers. See C.256, C.257 for overheads for presentation including transparencies. At C.257 is programme for ‘Final LINK Programme Presentations to Unilever (Colworth) July 27 1994’. C.258-C.262 ‘LINK DTI Proposal / Offer Letter’ 1989-1993 Contents of folder so inscribed divided into five for ease of reference: correspondence and papers. ‘LINK Costings’ 1989-1990 Contents of folder so labelled: manuscript notes, summary of programme costs, etc. ‘Institute Shell’ 1990-1994 1990-1991 of folder so labelled: correspondence and Contents papers. Department of Trade and Industry Companies ‘LINK Management Committee Meetings’ Contents of folder so inscribed: correspondence, agendas etc: 1990-1994 Contents of folder so labelled divided into four for ease of reference: correspondence and papers. ‘LINK Management Committee Minutes’ Contents of folder so labelled. C.267-C.270 ‘LINK’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 CAIN C22 ‘UCL LINK’ Cantante WVUINCTILo rat UU reference: papers pro [SmithKline Beecham] intr tha labelled divided into two for 2 ia bably for LINK presentation to SB Worthing, Sussex, 31 July 1994. far anca yn eacolt Vv ‘(Overhead) Transparencies - IRC’ Contents of folder so inscribed: includes Lilly’s manuscript notes and drafts. Found with LINK papers. C.274-C.304 General correspondence and papers 1988-1997 C.274 1988-1989 C.282-C.292 1992 C.276-C.281 1991 Includes project reports Includes project reports. Two folders. Includes scientific Biochemical Engineering LINK meeting. transparencies for presentations at C.293, C.294 1993 Six folders. Eleven folders. C.295-C.299 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Includes papers for ‘Progress Report 8 of the Biochemical Engineering Consortium’. Five folders. C.302-C.304 N.d. Three folders. C.305-C.320 National Research Development Corporation 1968-1978 See also C.392-C.395. ‘NRDC General’ 1968-1975 1968-1978 reference: papers re C.307-C.317 ‘NRDC Patents’ correspondence and Contents of folder so inscribed divided into two for ease of reference: correspondence and papers re support for work at UCL by the NRDC and patent applications. Contents of folder so inscribed divided into eleven for ease of patent applications etc. . 1969-1971 inscribed: correspondence and folder Contents of inscribed: correspondence and papers re patent application arising from work on porous reactors. so ‘NRDC Grant - EB-J2’ Contents of folder so ‘Porous reactors’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 bound papers enzymes including report to NRDC on final year of project. re NRDC funded polymer project on ‘N.R.D.C. Patents’ 1969-1971 Contents of papers re patent applications. folder so inscribed: correspondence and C.321-C.375 Science Research Council / Science and Engineering Research Council 1962-1994 Documentation of Lilly's SRC / SERC grants are presented in an approximately chronological order. in the sequence are Included with colleagues at UCL or other institutions and applications by UCL colleagues sent to Lilly for information. applications joint ‘EB’ reference numbers in the catalogue entries relate to UCL's own grant referencing system On (DSIR) by M.B. Donald. 1962-1970 C 321-6323 C.324-C.326 SRC grant B/SR/833 ‘Biochemical Fuel Cells’ Contents of folder inscribed ‘Fuel Cells’ divided into three for ease of reference: correspondence and papers. The initial application was made to the SRC’s predecessor organisation the Department of Scientific and Industrial Donald’s Research resignation from UCL in 1966 the details of the grant were amended to provide for the research to be conducted by Lilly and P.N. Rowe. 1978-1982 Contents of folder inscribed ‘SERC grant Effect of Cycling EBC7’ into reference: correspondence and and reports. SRC grant application ‘The Stability of Biological Catalysis in Reactor Systems’ SRC grant GR/A/87081 ‘Effect of cycling dissolved gas concentrations on microbial product formation’ for including three papers application divided ease of M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Application only. SRC grant application ‘A Biochemical Engineering Study to Improve Protein Processing’ Application only. Peter Dunnill. The applicant was Lilly’s UCL colleague C.329-C.332 Miscellaneous correspondence and papers re SRC grants 1969-1981 Contents of folder inscribed ‘SRC Research Grant Claim’ divided into four for ease of reference: includes grant applications. SERC grant GR/B 54520 ‘Pilot-Scale Fermentation’ 1980-1982 Contents of folder so inscribed ‘SERC Grant “Pilot-Scale Fermentation’ ’: application, report to SERC, etc. grant Stabilities of Pilot ‘Kinetics & GR/B 95707 ‘Stability of Natural 1981-1985 and Plant Plasmids in 1981-1985 Chemostat and Contents Stability” ’: grant applications, final report etc. inscribed ‘SERC folder of SERC grant Constructed Culture’ SERC Biocatalysts in Multi-Liquid Phase Reactions’ GR/B/60637 Contents of Lilly's folder inscribed ‘EB.D8.84 SERC Grant “Multi-phase Reactions” ’: includes final report. 1982-1985 SERC grant GR/C 17628 ‘The Integration of Fermentation and Microbial Protein Products’ This was a joint UCL (Lilly and P.H. Clarke) / Polytechnic of Central London (G.Holt) programme. Contents of ‘Fish application by N.M. Fish and Lilly, etc. inscribed Subsequent Processing Grant “Plasmid Operations for & Lilly EB.E6.8A’: folder Lilly M.D. NCUACS 150/7/06 University College London, C.1-C.971 C.337-C.339 SERC grant GR/C 70937 ‘Microbial Halogenation’ 1982-1988 Conients of foider inscribed ‘Microbial Haiogenation SERC GR/C 70937’ divided into three for ease of reference: applications, research report etc. 1982 (start date The application made in 1/1/83) was submitted by the University of Kent on behalf of the S.E. England Biotechnology Consortium (A.T. Bull, G. Holt and Lilly). An award was not initially recommended and a revised application was submitted. See also C.340-C.342, C.343. C.340-C.342 SERC grant GR/C 70937 ‘Microbial Halogenation’ 1984-1987 Contents of untitled folder divided into three for ease of reference: research reports, final report. See also C.337-C.339, C.343. ‘Fermentation and protein 1984-1986 The final serious illness. untitled folder: final report and related Contents correspondence. of See also C.337-C.339, C.340-C.342. report was much delayed because of Lilly's SERC grant GR/C 70937 ‘Microbial Halogenation’ SERC grant GR/C 99822 product recovery’ ‘SERC Grant EBF4’. application, research report, etc. reference: application and related correspondence. SERC ‘Spinks’ Studentship in Process Engineering in Biotechnology liquid-phase biocatalytic reactors’ Contents of untitled folder divided into two for ease of The investigators were N.M. Fish, Lilly and M. Hoare. Contents of folder so inscribed: Award ‘Design of two _ C.345, C.346 1984-1985 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.347, C.348 SERC grant GR/D/32895 ‘Kinetics of biological reactions involving a reactant-containing organic phase’ 1984-1988 ‘SERC grant EB.90 (1.7.85 - 30.6.88)’. into so application, grant report etc. inscribed divided two for Contents of folder of reference: ease SERC grant GR/D 75007 proteins during fermentation and downstream processing’ ‘Monitoring of enzymes and 1985-1988 Contents application, research grant report, etc. inscribed folder of with the project title: Biotechnology SERC_ biocatalyst interactions’ Studentship ‘Organic phase- 1985-1986 Contents of folder inscribed with project title: application, etc. C.350-C.360 ‘SERC’ a_ in May and was UCL begin 1986-1988 shortlisted to become The papers are presented in the order found. Contents of box folder so inscribed divided into eleven for ease of reference: includes drafts and transparencies for presentations. In January 1986 the SERC Biotechnology Directorate invited proposals from universities for the development of major disciplinary research programmes in biochemical was engineering. in September Biochemical invited Engineering Centre and the process of turning UCL’s proposal into a formal grant application. See C.361, C.362 1986-1989 Contents of folder inscribed ‘Integrated studies in biochem. eng (MDL{illy)/PD[unnill]/CRT[homas]/MH[oare]/NMF[ish])’ divided into two for ease of reference: applications, special research grant announcement, interim report, etc. This application arose from the selection of UCL as one of two centres for of biochemical For the background to this application see engineering. special SERC funding SERC GR/E 27027 Engineering’ ‘Integrated Studies in Biochemical C.361, C.362 Lilly M.D. NCUACS 150/7/06 University College London, C.1-C.971 C.350-C.360. studentship SERC Biotechnology (quota) ‘The effect of immobilization on organic phase - enzyme interactions’ Directorate research 1986-1987 Contents of folder inscribed with application. project title: includes SERC CASE [Co-operative Engineering] Awards Awards in Science and 1990-1994 Contents of folder inscribed ‘CASE Awards’: application, correspondence with Pfizer Ltd. C.365-C.368 SERC IRC Studentships 1990-1992 Contents of folder inscribed ‘IRC Studentships 1991, 1992’ divided includes PhD proposals and correspondence and papers re joint training of PhD students with other universities. for ease of reference: four into by A.P. M. University C.369-C.372 Ison UCL and The application to the SERC was rejected in November 1992 ‘in its present form’ and resubmission invited. Contents of folder inscribed ‘Mike Bushell’ divided into four for ease of reference: correspondence and papers re joint research proposal of Ison and Bushell. Bushell, SERC application Microbial Physiology Group, of Surrey ‘The Influence of Hyphal Morphology on Antibiotic Production in Submerged Culture’ 1991-1993 Contents of folder inscribed ‘UCL/Exeter SERC Grant Application UCL (J.M. Woodley and J.M. Ward) and Exeter (N.J. Turner and A.J. Willetts). SERC grant application ‘The Development of a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’ Lilly’s role in the proposed project was consultative. 1992’: grant applications from M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 SERC Biotechnology Directorate Research Studentship ‘Downstream Processing from Transketolase Catalysed 1992-1993 imtranctfarms bem ee Bioti ANSIVHAUONS Contents Research Studentship 1993’: includes application. inscribed folder ‘BT of [Biotransformation] The applicant was J.M. Woodley. for Visiting Fellowship Research SERC Applications Grants Two applications only. The proposers were A.P. Ison and J.M. Woodley. C.376-C.387 University Grants Committee C.376-C.383 ‘Grants (Various)’ 1982-1992 1982-1992 C.388-C.401 1984-1988 1968-1993 1968-1975 C.384-C.387 By research contract client ‘UGC Research Plan (Biotechnology)’ Contents of folder so inscribed divided into four for ease of reference: includes drafts of ‘College Research Plan for Biotechnology’. Contents of folder so inscribed divided into eight for ease of reference: correspondence and papers principally re UGC earmarked support for biotechnology and review of the UGC’s biotechnology initiative. 1968-1971 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers including letter agreement, research reports, etc. Beecham Research Laboratories project The amidase. ‘EBJ4 Beecham Grant’ involved work with the enzyme penicillin C.388-C.395 C.388-C.390 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Beecham EBJ4 Extension’ 1971-1973 Contents of folder extension to Laboratories’, research report, research agreement, etc. includes ‘Proposal for project supported by Beecham Research inscribed: so C.392-C.395 ‘Ferromagnetic Supports’ 1971-1975 Contents of folder so inscribed divided into four for ease of reference: correspondence and papers re patent questions with Beechams and Development Corporation. Research National €:396, 6397 Mead Research USA 1989-1991 Contents of folder inscribed ‘Mead’ divided into two for ease of reference: correspondence and papers including research reports. C.398-C.401 1990-1993 C.402-C.459 By research topic ‘Research at UCL to be Sumitomo Chemical Company Japan ‘Sumitomo’ divided into four papers re The project was titled ‘Reactor Evaluation for Enzymic Phenol Oxidations in Aqueous Organic Reaction Media’. The project was described as carried out by Sumitomo Chemicals’ Researcher’. Contents of folder inscribed for ease of reference: correspondence and arrangements including quotation. 1972-1997 In fact the folder contained minutes of only one ‘Antibiotic Process’ headed ‘Streptomyces’ meetings. Contents of folder so inscribed: minutes of meetings, etc. meeting. The other minutes are ‘Antibiotic Process Mtgs’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.403-C.408 ‘Baeyer-Villiger’ 1992-1996 Contents of folder so inscribed divided into six for ease of reference: correspondence and papers re Baeyer-Villiger Monooxygenase research in collaboration with University of Exeter (S.M. Roberts). C.409-C.412 ‘Biotransformation Research’ 1994-1997 Contents of folder so inscribed divided into four for ease of reference: includes agenda and papers for ‘Third Annual Research Meeting’ on ‘ The Development of a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’, 19 December 19985, etc. ‘Cholesterol Project (Northwick Park)’ and ‘Northwick Park Clinical Centre (Project)’ Contents of papers relating to Cholesterol Oxidase Project, 1972. inscribed: correspondence and folder so 1990-1996 ‘Exeter Visit’ C.414-C.422 C.423-C.425 See also C.423-C.425. ‘Collaboration with Exeter’ These papers were found in considerable disorder and are presented as found. Contents of folder so inscribed divided into nine for ease of reference: correspondence and papers re collaborative project ‘The Development of a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’. 1992-1995 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re collaboratio: with Exeter ‘The Development of a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’. of Many papers ‘Transketolase Project’. the are headed ‘Transketolase’ or M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Fermentation RAG [Research Advisory Group] ‘Flexible Biotransformations’ Contents of folder so inscribed: includes notes sent to Lilly for for biotransformation. bioprocessing comment flexible on C.428-C.436 ‘Halogenation’ 1983-1985 Contents of folder so inscribed divided into nine for ease of reference: includes research reports and bibliographical references. C.437-C.445 ‘Halogenation’ 1985-1986 C.446, C.447 1982-1985 C.448, C.449 ‘Protein Processing’ notes, research ‘1982 Plasmid Stability’ Contents of binder so inscribed divided into nine for ease research of reports, bibliographical references. reference: Contents of folder so inscribed divided into two for ease of reference: includes drafts of case for support of proposed investigation ‘Stability of Natural and Constructed Plasmids in Chemostat and Pilot Plant Culture’. 1986-1989 Contents of folder so inscribed divided into two for ease of reference: papers re SERC grant of Lilly's UCL colleagues P. Dunnill and M. Hoare ‘A biochemical engineering study to improve the separation of biological material, especially proteins’ Contents of plastic folder so labelled divided into two for ease of reference: ‘2nd Annual Report (1994)’ and papers re organising December 1996 research meeting. ‘Transketolase Research Grant’ C.450, C.451 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 These papers relate to collaboration with the University of Exeter ‘The Deveiopment of a Biocataiytic Process for Large Scale Carbon-Carbon- Bond Synthesis’. The annual report comprises presentations made at the 2nd Annual Research Meeting, 15/16 December 1994. C.452, C.453 ‘Transketolase’ 1994-1995 Contents of folder so inscribed divided into two for ease of reference: research meetings, etc. correspondence papers and re These papers relate to collaboration with the University of Exeter ‘The Development of Biocatalytic Process for Large Scale Carbon-Carbon- Bond Synthesis’. a Included at C.453 is including Lilly. a photograph of ‘Carbons United’ C.454-C.459 C.460-C.471 1990-1993 C.460-C.472 Patents 1990-1994 See also C.943. application, Bioconversion ‘TK[transketolase]’ Contents of folder so inscribed divided into six for ease of papers for UCL- reference: BBSRC grant Exeter-Edinburgh-Liverpool Collaborative Group 4th Annual Research Meeting, 6 December 1996. See also C.472. Contents of folder so inscribed divided into twelve for ease of reference: correspondence and papers re patenting biomass image analysis system. At C.471 are the contents of a plastic folder found inside the principal folder. ‘Patent’s application’ and ‘Image Analysis (Protection) M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Colin Thomas - Grants’ 1993-1994 Contents papers re patent. of foider so inscribed: correspondence and See also C.460-C.471. C.473-C.757 TEACHING AND TRAINING 1959-1998 C.473-C.577 ‘Teaching notes’ C.578-C.757 ‘Summer courses’ C.473-C.577 ‘Teaching Notes’ 1959-1998 Contents of Lilly's ‘Teaching Notes’ boxes. by of Cells’, ‘Production ‘Disruption C.473-C.475 of untitled folder: Organisation Microorganisms’, duplicated manuscript lecture ‘Lecture Notes Philadelphia 1969’ The dating of much of this material is problematic. headed Contents ‘Preparation of Immobilised Enzymes’, also identified as ‘© Dunnill & Lilly 1970’; ‘Lecture List Enzyme Technology Course, 7-11 September 1970’, etc Contents of folder so inscribed divided into three for ease notes ‘The of reference: of Content and Enzymes of Microorganisms’, etc. also Most of the papers in the folder were photocopies of the papers at C.473-C.475, and have not been retained. ‘B18 Microbial Product Formation Productivity’ Contents of folder so inscribed divided into two for ease of reference: and background headed ‘Fermentation in including to Enzyme Production’, manuscript material, typescript Relation notes notes and C.477-C.478 typescript notes 1959-1970 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 identified as ‘© Dunnill & Lilly 1970’. ‘Biochemical Reactors’ 1971-1972 Photocopied pages of figures for Lecture Courses on Fermentation Biochemical Engineering. Technology M.Sc. for in ‘E 830 Anaerobic Fermentations’ Contents folder background material. of so inscribed: manuscript notes, Latest bibliographical reference, 19771. ‘E 830 Introduction to Fermentation Technology’ of Contents folder background material. 1981. so inscribed: manuscript Latest bibliographical notes, reference, 1974-1979 C.482-C.485 ‘Design Projects’ photocopied manuscript ‘Chapter ‘Introduction to Fermentation Design’ Contents of folder so inscribed divided into four for ease of reference: manuscript notes and drafts, etc. Includes 3 Medium sterilization’ paginated 8-42 and ‘Chapter 5 The fermentors design’. Latest bibliographical reference 1981. Contents of folder so inscribed: manuscript and typescript notes. Contents of folder so inscribed: figures, manuscript notes, erc ‘Fermentation Kinetics (Batch)’ Latest date in notes ‘17/9/76’. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘M.Sc. Design Project 1982’ 1981-1982 C.489-C.492 ‘Course in Biochemical Engineering’ 1982-1984 reference: Contents of ring binder so titled divided into four for ease of and examination arrangements, notes for research students, safety regulations, etc. timetables, outlines, course tutorial C.493-C.495 ‘Lecture Notes’ Contents of folder so inscribed divided into three for ease of reference: papers for overhead projections including transparencies, of Fermentation Process’, ‘Penicillins’, etc. ‘Fermentation Products’, ‘Types Latest bibliographical reference 1986. figures, typescript 1987, 1993 C.499-C.507 ‘Lecture Notes’ C.496-C.497 Latest bibliographical reference, 1987. Contents of untitled folder: references, figures, notes etc re sterilisation Contents of untitled folder divided into two for ease of reference: manuscript notes, product literature, background papers 1988-1996 Contents of folder so inscribed divided into nine for ease of reference, manuscript and notes and drafts, figures, background papers, etc., re fermentation, scale- Up; lc, Contents of untitled folder: manuscript notes, figures for lectures on ? fermentation technology Includes manuscript notes headed ‘B18 - Lecture 4’, Latest bibliographical reference 1989. M.D. Lilly NCUACS 150/7/06 C.509-C.512 University College London, C.1-C.971 Contents of untitled binder divided into four for ease of reference: ijecture course or courses, October - December 1989, November 1990 and October-November 1993 (photocopies) manuscript notes for 1989-1993 There is no general heading for the 1989 lectures (C.509, C.510). include ‘Enzyme Systems’, ‘Reactor Systems with Microorganisms’, ‘Costs of fermentation’, ‘Continuous culture’, etc. individual lectures Titles of 1990 lectures The ‘Process Development’ and the 1993 lectures (C.512) are headed ‘Biochem. Eng. Fermentation’. (C.511) headed are C.513-C.514 ‘Teaching’ 1990-1993 Contents of folder so inscribed divided into two for ease of reference: drafts correspondence, lecture lists. manuscript typescript notes, of folder so Includes material re course planning including courses given by Department of Biochemistry for biochemical engineers. notes, inscribed: 1991-1996 ‘Industrial Visits’ ‘Departmental Lecture Notes’ Includes material re course planning. Contents of industrial colleagues, internal memos, etc. Contents manuscript typescript drafts, correspondence, lecture lists, etc. lecture lists, figures, etc. Contents of folder so inscribed: includes typescript notes, Contents of folder so inscribed: manuscript notes. inscribed: correspondence with ‘Industrial Fermentation Notes’ 1991-1995 'E839° folder so M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Most of the material is undated. C.519, C.520 ‘Introduction to Biochemical Engineering E839 and B.28 (part 1) courses’ Typescript notes re lecture courses. lecturers The UCL Keshavarz-Moore and Lilly. were colleagues P. Dunnill, E. Two folders. C.521-C.529 ‘Lecture Notes’ 1995-1997 Contents of folder so inscribed divided into nine for ease of reference: typescript notes, figures, etc Titles ‘Fermentation Scale-up’, ‘Fermentation Sterilisation’, etc. ‘Fermentation Development’, Process include by Engineering and Physical ‘Fermentation’ C.530-C.547 C.530-C.534 Integrated Graduate Development Scheme (IGDS) for Bioprocessing Module 2 Fermentation, Advanced Centre for Biochemical Engineering, UCL The scheme was sponsored by the Biotechnology and a scheme Biological Science Research Council within operated the Science Research Council. programme brochure and course feedback. This was ‘Module 2: Scheme for Bioprocessing’, October 1994-January 1995. Integrated Graduate Development Contents of ring binder so labelled divided into ease course notes. for daily programmes, Contents of folder so inscribed divided into two for ease of reference: includes papers re course preparation, |GDS ‘IGDS - Fermentation Module’ C.535, C.536 of reference: delegates list, 1993-1996 1993-1995 five Lilly M.D. NCUACS 150/7/06 University College London, C.1-C.971 C.537-C.538 ‘Fermentation Kinetics’ Contents of folder so inscribed divided into two for ease of reference: includes papers re fermentation case study. C.539-C.541 ‘GDS - BT Module’ 1994-1995 reference: Contents of folder so inscribed divided into three for ease of questions, practicals, 3 Biotransformations’. etc study Module ‘IGDS drafts exam case mock for re ‘IGDS -BT Module’ 1995-1996 Contents of folder so catalysts, biocatalytic reactors. inscribed: drafts re immobilized C.543-C.547 ‘New MSc Course in Bioprocessing (IGDS)’ and re UCL, papers Course notes A Hands-on Course on Scaling up Technology’, Advanced Centre for Biochemical Engineering, 11-15 April 1994 Contents of folder so labelled divided into five for ease of reference: course administration. correspondence ‘Biochemical Engineering Practical Course for the Institute of Biochemical Engineering, UCL, 25-29 April 1994 1995, 1997 Training courses delivered by the Advanced Centre for Biochemical Engineering at UCL. Lilly contributed to the teaching. Modular Training for the Bioprocess Industries Biotechnology’, C.549-C.552 Course notes. Advanced Centre for M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.974 ‘Fermentation’ Contents of ring binder so labelled. This was ‘Book 1 of 2’. In original binder. Table of contents, daily programme, course notes, etc. ‘Fermentation’ Contents of ring binder so labelled. This was ‘Book 2 of 2’. In original binder. Table of contents, daily programme, course notes, etc. ‘Principles of Fermentation Processes’ Contents of ring binder so labelled. In original binder. and Scale-up In original binder. section contents, daily programme, Contents of ring binder so labelled. Delegate profiles, course notes, etc. ‘Fermentation Biology/Engineering Interface’ Design Section contents, daily programme, course notes, case studies, etc. studies, etc. Section contents, daily programme, course notes, case ‘Fermentation Process Operation’ Contents of ring binder so labelled. In original binder. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.553-C.555 Undated notes and drafts C.553 ‘Enzyme Reactor Kinetics’ Contents of folder so inscribed. ‘Biochemical Reactors’ Contents of folder so inscribed. ‘Fermentation Culture E818’ Kinetics (Continuous)’ and ‘Continuous Contents of folder so inscribed. C.556-C.577 Miscellaneous correspondence and papers re teaching and training. 1960s -1998 Many papers found loose. 22 folders. C.578-C.757 ‘Summer Courses’ papers BEng re undergraduate course Biochemical course in 4-year At C.563-C.566 are structure Engineering, 1984. and At C.576, C.577 is background material re biochemical engineering courses at other institutions. At C.574, C.575 is background material etc re Thames Water sewage treatment etc. Contents of ring binders so labelled: course documentation These courses were given by UCL staff including Lilly and others for participants from industry and academe, many from overseas. Contents of Lilly's ‘Summer Courses’ boxes. ‘Course in Biochemical Engineering’ 1967-1996 C.578-C.680 1979-1991 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 including programme, list of participants, lecture notes etc. C.578-C.582 ‘Advanced Biochemical Engineering Course (No.3)’ Five folders. C.583-C.588 ‘Biochemical Engineering Course (no.4)’ Six folders C.589-C.595 ‘Biochemical Engineering Summer Course (No.5’) Seven folders. C.596-C.602 ‘Biochemical Engineering Course (6)’ Seven folders. Eight folders. Eight folders. Eight folders. C.619-C.626 ‘Biochemical Engineering Summer Course (No.9)’ C.611-C.618 ‘Biochemical Engineering Summer Course (No.8) C.603-C.610 Biochemical Engineering Summer Course (No.7)’ Nine folders. ‘Biochemical Engineering Summer Course (No. 10)’ ‘Biochemical Engineering Summer Course (No.1 1)’ C.627-C.635 C.636-C.644 Nine folders M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.645-C.653 ‘Biochemical Engineering Summer Course (No.12)’ Nine folders. C.654-C.661 ‘Biochemical Engineering Summer Course (No.13)’ Eight folders. C.662-C.670 ‘Biochemical Engineering Summer Course (No.14)’ Nine folders. C.671-C.680 ‘Biochemical Engineering Summer Course (No.15)’ Ten folders. Five folders. for C.681-C.757 1970-1996 Engineering Course: Pre-1981 C.686-C.687 C.681-C.685 Lecture list, course, 7-11 September 1970, found tagged together. participants, lecture notes, list of etc ‘Enzyme Technology Course’ Biochemical Miscellaneous’ Miscellaneous correspondence and papers re summer courses 1977-1981 Contents of folder so inscribed divided into five for ease of reference: FEBS {Federation of European Biochemical Societies] Advanced ‘Biochemical Engineering: the Translation Course No.55 of and __ Industrial Processes’, 11-13 September 1978. Contents of folder so inscribed divided into two for ease of reference: lists of participants, accounts etc. ‘All correspondence’ correspondence and papers re C.688-C.692 Biochemistry and Microbiology M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.693-C.707 ‘Summer Course Notes / Old Notes & Drawings’ 1973-1979 Contents of box folder so inscribed divided into fifteen for ease of reference: includes course notes for ? Advanced Biochemical Engineering Course, 10-14 September 1979, a copy of the programme of which is at C.695. At C.702 is copy of ‘Biochemical Reactors’, Lilly's Plenary Lecture, Achema Congress, Frankfurt, 1973 and at C.704 a copy of ‘Developments in Biocatalysis’, Lilly's Plenary Lecture at Achema Congress, 22 June 1979. a folder inscribed The papers at C.706 were found in ‘Malcolm Lilly’ and the papers at C.707 in a folder inscribed ‘Methods in Enzymology’. C.708-C.710 ‘BESC 1983 Course Admin’ 1982-1983 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re arrangements including course questionnaires for 1982 and 1983. C.711-C.714 ‘BESC 1983 Course Enquiries’ 1982-1983 ‘BESC 1983 Masters’ C.716-C.720 ‘BESC 1984 Admin’ Contents of folder so inscribed: includes registrations. Contents of folder so inscribed: information for speakers, participants etc. 1984-1988 Contents of folder so inscribed divided into five for ease of reference: includes course questionnaires. C.724-C.727 ‘Summer course’ C.721-C.723 Course notes 1983-1985 Three folders. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Contents of folder so inscribed divided into four for ease of transparencies, reference: 1095 AQ9A snd int ManuSCript i904 G@NG 1900 meetings. including course notes. £ C.728-C.729 ‘Biochemical Engineering Summer Course’ 1985, 1987 Contents of folder so inscribed divided into two for ease of reference: photocopied manuscript ? course notes. ‘BE Short Course’ 1988-1989 Contents of folder so inscribed: annotated course notes, etc. C731-C2733 ‘BESC 1988’ 1987-1988 Contents of folder so inscribed divided into three for ease of reference. 1988-1989 1989-1990 C.736-C.737 ‘BESC 1990’ C.734-C.735 ‘BESC 1989’ Contents of folder so inscribed divided into two for ease of reference: includes course questionnaires. Contents of folder so inscribed divided into two for ease of reference: includes course questionnaires. reference: includes course questionnaires. Contents of folder so inscribed divided into two for ease of ‘Lecture notes Course (1990)’ 6pp typescript + figures. C.739-C.740 14th Biochemical Engineering Summer ‘BESC 1991’ 1990-1991 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.741-C.742 Course notes Typescript transparencies etc ? for 1991 course. some annotated; notes, manuscript notes: Two folders. ‘International Course 1992’ 1991-1992 Contents of so papers re arrangements. folder inscribed: correspondence and The course was cancelled because there were not enough applicants to cover the costs. C.744-C.750 Miscellaneous course notes 1967-1996 Papers found loose or in unidentified folders. Seven folders. C.751-C.754 ‘Teachers Conference’ 1986-1995 C.755-C.757 Engineering and and papers re INSET 1990-1992 Papers found with summer course material. Correspondence Biochemical Industries Contents of folder so inscribed divided into four for ease of reference: programmes, lists of participants, course notes etc for INSET Seminars on Biochemical Engineering and the Biotechnology-Based Industries. Three folders. Seminars the Biotechnology-Based Papers found with summer course material. Principally course questionnaires. M.D. Lilly NCUACS 150/7/06 University Coliege London, C.1-C.971 C.758-C.891 PERSONNEL 1964-2002 An alphabetical sequence of departmental visitors, research students, etc Lilly's ‘personnel’ files re Includes arrangements to career. visit, research, publications, C.760-C.761 Bar. Two folders. 1980-1989 1971-1981 1995-1997 1992-1994 1970-1971 1979-1984 Bro. (1) Five folders. C.764-C.768 1975-1976 1973-1996 C.770-C.774 Bu. C.770 1973-1974 Lilly M.D. NCUACS 150/7/06 University College London, C.1-C.971 1977-1978 1979-1980 1989-1996 1972-1977 Che. 1974-2002 Three folders. 1988-1994 1973-1974 C.780-C.782 Co. Letter, 26 June 2002, is from Sheila Lilly. 1970-1973 C.785, C.786 Das. 2 folders. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.787-C.789 1988-1991 C.793-C.795 fae C.793 1983-1985 1974-1979 1964-1976 1983-1996 1986-1987 1991-1996 Gr. 1971-1974 1969-1987 C.796 1969-1970 C.796-C.799 1990-1991 1975-1980 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 1983-1984 1967-1973 1972-1975 1991-1994 C.803-C.804 Har. 2 folders. C.806-C.811 Hob. Much of the material was undated and the arrangement is tentative. Six folders. 1974-1975 Jo. C.816 1988-1991 1972-1976 C.812 1972-1973 C.812-C.814 Hu. 1973-1976 1988-1995 C.816-C.822 1972-1974 M.D. Lilly NCUACS 150/7/06 C.817-C.818 C.819-C.821 University College London, C.1-C.971 Three folders. 1993-1995 NZ. 1076 1968-1972 1985-1988 1981-1984 La. 1974-1975 C.828 1972-1973 1972-1975 C.828-C.829 1974-1975 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.834-C.835 Mat. Two folders C.838-C.840 1970-1975 1991-1992 1991-1995 1972-1975 1975-1994 C.838 1976-1980 1993-1994 C.842-C.847 1976-1986 1984-1985 Pac. Six folders 1968, 1972 1989-1992 M.D. Lilly University College London, C.1-C.971 C.850-C.851 Reg. C.850 1970-1971 1972-1975 1970-1975 1973-1974 1969-1974 1992-1994 1986-1992 1988-1991 1995-1996 1978-1979 1972-1973 C.862-C.865 Su. Four folders. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.867-C.870 Var. Four folders. C.873-C.874 War. (2) Two folders. 1978-1982 1976-1983 1971-1976 1989-1992 1971-1976 1967-1968 Wo. Six folders. C.877-C.882 1989-1991 C.886-C.891 C.884-C.885 Wy. C.884 1970-1973 1988-1998 1989-1990 1970-1974 M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 1989-1991 C.887-C.889 1994 Three folders. C.890-C.891 N.d. Two folders. C.892-C.971 MISCELLANEOUS 1966-1997 C.892-C.965 Topics C.966-C.971 Shorter correspondence and papers C.892-C.965 C.895-C.905 1984-1990 1966-1997 1990-1996 C.892-C.894 Annual Lecture Correspondence and papers re arrangements for Annual Lecture of the Centre for Biochemical Engineering and Biotechnology. 1988-1996 Correspondence and papers re joint project between BCS and UCL for “state-of-the-art” computer-based data-logging for biological reactors’ (C.902), etc. Biotechnology Computer Systems Ltd (BCS) ‘a control and system C.906-C.907 Bursaries Three folders. Eleven folders. the development of M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 Correspondence and papers re departmental bursaries administered by Lilly. Two folders. C.908-C.912 ‘Centre for Biotechnology Architects Drawings’ and ‘Foster Court’ 1982-1984 Contents of folder so inscribed divided into five for ease of reference. ‘Equipment for Old Pilot Plant’ Contents of folder so inscribed: includes ‘Initial study into the upgrade of the Pilot Project and Conirol Laboratory and the development of a 21st [?century] Training Facility’, n.d. C.914-C.929 ‘Fermenter Drawings’ 1966-1987 1990-1995 1990-1995 Pharmaceuticals, !Cl C.930-C.941 Link Programme C.930-C.932 ‘Link Grant’ Research, Unilever Research, See also C.236-C.304. Beecham Shell Contents of folder so inscribed divided into sixteen for ease of reference: includes product literature. This was a research programme at UCL in association with Biological SmithKline Products, the Department of Trade and Industry and SERC. 1990 Progress Report No.1 for liaison meeting at UCL on 16th November 1990 Contents of folder so inscribed divided into three for ease of research partners and papers for presentation. includes correspondence with reference: C.933-C.941 Progress Reports 1990-1994 C.933 Lilly M.D. NCUACS 150/7/06 University College London, C.1-C.971 Progress Report No.2 for liaison meeting at UCL on 8th May 1991 RAn., 4004 Progress Report No.3 for Centre on 14th November 19914 ' liaison meeting at the Shell Progress Report No.4 for House on 8th May 1992 liaison meeting at Unilever Progress Report No.5 for liaison meeting at Warren House on 6th November 1992 Progress Report No.6 for liaison meeting at New Horizons Court on 7th May 1993 Progress Report No.9 ‘Old Pilot Plant Re-opening’ Progress Report No.8 for liaison meeting at UCL on 7th April 1994 Progress Report No.7 for liaison meeting at UCL on 11th November 1993 1971-1991 Contents of folder so inscribed: includes correspondence and patent specifications. See also C.460-C.472. Contents alterations and re-opening, 2 June 1981. inscribed: folder so of 1979-1981 includes papers re ‘Patents’ M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.944-C.946 ‘PhD / RA Notes’ 1982-1997 Contents of folder so inscribed divided into three for ease of grant application, etc. reference: research reports, results, thesis C.947-C.948 ‘Provost’ 1980-1986 Contents of folder so inscribed: correspondence with UCL Provost, Sir James Lighthill. 1980-1981 1985-1986 C.949-C.950 ‘Provost's Advisory Group on Bioengineering’ 1992, 1996 1991-1996 C.952-C.954 so inscribed: ‘SERC Centre’ ‘Scale Up Review + SB [Smithkline Beecham] ‘ Contents of folder re UCL / Smithkline Beecham collaboration on Fermentation Scale- up. principally Contents of folder so inscribed divided into two for ease of reference: includes papers for Biotransformation Research Advisory Group. 1986-1989 At C.952 Biochemical Engineering ‘Response to Engineering the SERC Directorate’, latest bibliographical reference 1986. Contents of folder so inscribed divided into three for ease of reference. and the Biochemical Biotechnology the UCL Department of Chemical is Initiative of See also C.23. M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.955-C.963A ‘TAU [Tel Aviv University] Collaboration’ 1983-1997 SO collaboration inscribed: between papers re University. correspondence and Tel-Aviv UCL and include E. Katzir-Katchalski and A. Correspondents Freeman. See also H.59A. 1983 Includes programme for conference on ‘Achievements and Expected Tel-Aviv University, 7-9 June 1983. Lilly talked on immobilized biocatalysts in a session on industrial applications. Biotechnology’, Developments in 1994 Two folders. C.959-C.960 Includes application for a joint UK-Israel Research Grant (C.960). M.D. Lilly NCUACS 150/7/06 University College London, C.1-C.971 ‘Visitors to UCLbe’ 1991, 1993 Contents arrangements, letters of thanks. folder of so inscribed: correspondence re 1993 papers relate to visit from Wageningen Agricultural University, The Netherlands. ‘Wolfson Application’ Contents of folder so inscribed: papers relate to proposed new research laboratory for process engineering. C.966-C.971 Shorter correspondence and papers 1973-1994 1987-1990 1984-1985 1992-1996 M.D. Lilly NCUACS 150/7/06 SECTION D PUBLICATIONS, D.1-D.366 1962-2003 D.1-D.361A OWN PUBLICATIONS D.362-D.366 PUBLICATIONS CORRESPONDENCE D.1-D.361A OWN PUBLICATIONS 1962-2003 The numbering of the papers corresponds with that in the bibliography at A.2. (1) 1962 Cell wall precursors in Escherichia coli 26-26. J. Gen. Microbiol. 28, ii-iii. Typescript draft and off-print. Off-print only. P.H. Clarke and Contents of Lilly’s folder: off-print, drafts, correspondence. 1963 (With (3) P.M. Meadow) The accumulation of nucleotides by Escherichia coli strain 26- 26. J. Gen. Microbiol. 32,103-116 (2) 1962 (With P.H. Clarke) A general structure for cell walls of Gram-negative bacteria. Nature 195, 516-517 Contents of Lilly's folder: off-print, letter from co-author (4) 1965 (With R.J. Ertola and F.C. Webb) Production of cell a _ microbiological process. Biotechnol. Bioeng. 7, 309-319 (5) 1965 (With W. Hornby, C. Money and E.M. Crook) Enzymes on solid supports. Biochem J. 95, 45-46P Contents of reference: typescript drafts. into two for ease of and manuscript Lilly's folder divided off-print, correspondence, tissue from hydrocarbons by 1964-1965 M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (6) 1965 Extraction and separation of nucleotides from Escherichia coil. Biotechnoi. Bioeng. 7, 335-342 1959-1965 Lilly's folder divided into two for ease of Contents of reference: off-prints of Lilly's paper and related papers by others, draft, data, etc 1966 (With (7) Effects Escherichia coli. J. Gen. Microbiol. 45, 479-488 Hadjipetrou and energy ferricyanide L.P. on of T. Gray-Young) by production Contents of Lilly’s folder: off-print, draft 1966 (With (8) The preparation and properties of ficin chemically attached to carboxymethyl cellulose. Biochem J. 98, 420-425 Hornby and Crook) W.E. E.M. Contents of Lilly’s folder: off-print, draft. into five D.11-D.15 P.H. Clarke) D.16-D.17 1966 (With 1966-1967 for ease of 1966, 1976 A. Boddy and Lilly's folder divided Contents of reference: off-print, drafts, correspondence etc. Lilly's folder divided (9) 1966 (With W.E. Hornby and E.M. Crook) The kinetics of carboxymethylcellulose-ficin in packed beds. Biochem J. 100, 718-723. Periodic (10) changes Pseudomonas aeruginosa in continuous culture. J. Gen. Microbiol. 45, ii- iii. 1966-1967 Contents of into two for ease of reference: photocopy of paper and offprint of later (1967) related paper, correspondence, manuscript notes, figures. (11) 1966 (With T. Gray Young and L.P. Hadjipetrou) The theoretical aspects of biochemical fuel cells. Biotechnol. Bioeng. 8, 581-593. Contents of Lilly’s folder: off-print, drafts. Baidya and F.C. Webb) The 1967 (With T.K.N. D.19-D.20 in amidase synthesis by (12) M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 utilization Biotechnol. Bioeng. 9, 195-204 of mixed sugars in continuous fermentation. Contents of reference: off-print, drafts, manuscript notes, figures, etc into two for ease of folder divided Lilly's (13) 1967 (With P. Dunnill, P.M. Dunnill, A. Boddy and M. Houldsworth) The large of prolyl-tRNA synthetase from Phaseolus aureus. Biotechnol. Bioeng. 9, 343-356 isolation scale Contents of Lilly’s folder: off-print, draft. (14) 1967 (With D.S. Flynn) A method for the control of the dissolved oxygen tension in microbial cultures. Biotechnol. Bioeng. 9, 515-531. Off-print only. to the Mackereth oxygen D.25-D.26 Off-print only. Contents of Lilly's folder: off-print, correspondence, drafts. (16) 1967 Enzyme synthesis in micro-organisms. Process Biochem. 2, February, 17-21 (15) 1967 (With D.S. Flynn, D.G. Kilburn and F.C. Webb) Modifications electrode. Biotechnol. Bioeng. 9, 623-625 1965-1967 M.A. (17) 1967 Houldsworth) by Pseudomonas aeruginosa 8602 in continuous culture. J. Gen. Microbiol. 4S. 137-145 Contents of two folders of Lilly’s, one inscribed with the title of the paper and the second inscribed ‘1967 (Process (18) enzymes. Process Biochem. 2, July, 13-15 Dunnill) Contents of reference: proof, drafts Lilly's folder divided into two for ease of P.H. amidase Boddy, of Large scale isolation of 1967 (With P. Clarke and D.27-D.28 (With A. Regulation synthesis M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Large Biochem) off-print, correspondence, drafts, manuscript notes, duplicated and printed background materiai. (General)’: scale (19) 1968 (With W.E. Hornby and E.M. Crook) Some changes in the reactivity of enzymes resulting from their chemical attachment to water-insoluble of cellulose. Biochem J. 107, 669-674 derivatives 1966-1968 Contents of Lilly's folder: off-print, drafts, correspondence. (20) 1968 (with G. Kay, A.K. Sharp and R.J.H. Wilson) Preparation and use of porous sheets with enzyme action. Nature 217, 641-642 Contents of Lilly’s folder: off-print, proof, correspondence. P (21) 1968 (With Catabolite synthesis continuous culture. J. Gen. Microbiol. 51, 225-234 .H. Clarke and M.A. Houldsworth) of amidase in induction aeruginosa repression by Pseudomonas 8602 and the D.33-D.37 operation 1967-1968 reactors using of biochemical Contents of Lilly's folder: off-print only. Contents of Lilly’s folder: off-print, drafts, letter from E.M. Crook. (22) 1968 (With G. Kay, A.K. Sharp and R.J.H. Wilson) The fixed enzymes. Biochem. J., 107, 5P 1978 (24) 1968 G. The preparation dehydrogenase attached to water-insoluble particles and sheets. Biochem J. 108, 845-853 Contents of for ease of reference: off-print, correspondence, drafts, comments of the referees, figures. (23) 1968 (With A.K. Sharp) The kinetics of enzymes attached Chemical Engineer 215, 12-18. Lilly's folder divided into R.J.H. kinetics and lactate Wilson of water-insoluble 1967-1968, (With and to polymers. The five Kay) M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Contents of Lilly's folder: off-print, draft, figures. (25) 1968 (With R.J.H. Wilson) The kinetics of a novel cyclic of polynucleotide phosphorylase or adenosine diphosphate plus adenosine triphosphate. Biochem J. 108, 887-895 reaction system the assay and use its in Contents of Lilly’s folder: off-print, draft. 1968 (With R.J.H. (26) The preparation and properties of pyruvate kinase attached to porous a two-enzyme continuous-feed reactor. Biochem J. 109, 137-141 operation sheets, Wilson Kay) and and the G. of Contents of Lilly’s folder: off-print, draft. D.41-D.44 (27) 1968 (With D.A. Self and D.G. Kilburn) The influence of dissolved oxygen partial of various enzymes in mouse LS cells. Biotechnol. Bioeng. 10, 815-828 pressure on level the D.46-D.47 four for ease of figures, drafts, Contents of Lilly's folder: off-print, draft, figures. Lilly's folder divided into correspondence, Contents of reference: off-print, manuscript working. (28) 1968 (With P. Dunnill, R.A. Fisher, H. Harris and M. Houldsworth) Large-scale isolation of acid phosphatase from human erythrocytes. Biotechnol. Bioeng. 10, 829-843 1967-1969 (29) 1969 (With D.G. Kilburn, D.A. Self and F.C. Webb) The effect of dissolved oxygen partial pressure on the growth and carbohydrate metabolism of mouse LS cells. J. Cell. Sci. 4, 25-37 (30) 1969 (With P.H. Clarke) The regulation of enzyme synthesis during growth. X/Xth Symp. Soc. Gen. Microbiol. folder divided into two for ease of report, correspondence, Contents of reference: drafts. 1968-1969 D.48-D.49 referee's off-print, Lilly’s M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (ed. P.M. Meadow and S.J. Pirt), pp. 113-159. Cambridge: University Press Contents of reference: off-print, correspondence, draft, data. Lilly's folder divided into two for ease of (31) 1969 (With P. Dunnill) Enzymes: a new technology. Science Journal April, 59-63 Off-print and duplicated typescript. (32) 1969 (With P.H. Clarke, M. Houldsworth, J.A. Currie and P. Dunnill) The isolation of an aliphatic amidase from Pseudomonas aeruginosa. Biotechnol. Bioeng. 11, 283- 292 Contents of Lilly’s folder: off-print, drafts. D.52-D.53 penicillin using D.55-D.56 of penicillin amidase. into two for ease of Contents of reference: off-print, drafts, figures etc. folder divided Lilly’s Contents of Lilly’s folder: off-print, draft, figures. (33) 1969 (With D.A. Self and G. Kay) The conversion of benzyl an Biotechnol. derivative insoluble Bioeng. 11, 337-348 to 6-amino-penicillanic acid (34) 1969 (With R.J.H. Wilson) Preparation and use of insolubilised amyloglucosidase for the production of sweet glucose liquors. Biotechnol. Bioeng. 11, 349-362 Perlman), pp. 225-247. New York: Academic Press (35) 1969 (With A.K. Sharp and G. Kay) The kinetics of B- galactosidase sheets. Biotechnol. Bioeng. 11, 363-380 (36) enzymes from micro-organisms - the development of In Fermentation Advances (ed. continuous process. intracellular a D Contents of folder divided reference: off-print, drafts, figures. into two for ease of 1969 (With P. Dunnill) Isolation of porous cellulose attached to D.57-D.59 Lilly's M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Contents of reference: off-print, drafts. Lilly’s folder divided into three for ease of 1969 (With (37) F.C. Webb) The energetics of mammalian cell growth. J. Cell. Sci. 4, 645- 654 Kilburn D.G. and Off-print only. G. Kay) The chemical attachment of (38) 1970 (With chymotrypsin to water-insoluble polymers using 2-amino- 4,6 dichloro-s-triazine. Biochim. Biophys. Acta 198, 276- 285 Contents of Lilly’s folder: off-print, draft, figures. D.62-D.63 (39) 1970 (With P. Dunnill and J.A. Currie) Continuous enzyme prolyl-tRNA synthetase from Phaseolus aureus. Biotechnol. Bioeng. 12, 63-74 processing: isolation the of 1969-1971 on coli. Antonie D.65-D.70 Escherichia ferricyanide Off-print only. Contents of Lilly's folder so inscribed divided into two for ease of reference: off-print, correspondence, drafts. (40) 1970 (With L. Hadjipetrou and. P. Kourounakis) Effect of van Leeuwenhoek 36, 531-540 1970-1971 Follows and P. (41) Dunnill) bakers yeast (Saccharomyces cerevisiae) by disruption in an industrial homogeniser. Trans. Instn. Chem. Engrs. 142-148 (42) 1971 (With J.R. Wykes and P. Dunnill) Conversion of tyrosine to L-dihydroxy-phenylalanine using immobilised tyrosinase. Nature 230, 187 Contents of reference: off-print, correspondence, drafts, figures, etc. folder divided Hetherington, M. from for ease of 1970-1971 D.71-D.72 into six 1971 (With P.J. Lilly's Release of protein M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Lilly's Contents of into two for ease of reference: off-print, drafts, figures, duplicated background papers. folder divided (43) 1971 (With S.P. O'Neill, J.R. Wykes and P. Dunnill) An __ ultrafiltration-reactor soluble immobilized enzyme. Biotechnol. Bioeng. 13, 319-322. system using a_ Contents of Lilly’s folder: off-print, correspondence, drafts. D.74-D.75 (44) 1971 (With S.P. O'Neill and P. Dunnill) A comparative a packed bed study of immobilised amyloglucosidase in reactor stirred tank reactor. Biotechnol. Bioeng. 13, 337-352 continuous feed and a Contents of Lilly's folder so inscribed divided into two for ease of reference: off-print, correspondence, drafts. 1970-1971 1970-1971 M. (With (45) 1971 Dunnill) disruption Bioeng. 13, 549-560. an in Follows, P.J. Hetherington and P. by Biotechnol. homogeniser. baker's yeast D.76-D.77 1971 Lilly’s Stability industrial folder divided into two for ease of Release of enzymes from Contents of Lilly's folder: offprint, draft. (46) prolonged storage. Biotechnol. Bioeng. 13, 589 of immobilised, R-galactosidase on Contents of reference: off-print, correspondence, drafts, figures. (47) 1971 (With P.R. Foster and P. Dunnill) Salting-out of enzymes with ammonium sulphate. Biotechnol. Bioeng. Ne) Sac (48) 1971 steady states reactors. Chem. Eng. Sci. 26, 173-175 O'Neill and in continuous flow Contents of Lilly’s folder: offprint, drafts, figures. P.N. Rowe) Multiple stirred tank enzyme Contents of Lilly’s folder: offprint, drafts, figures etc. letter to journal editor, (With S.P. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (49) 1971 (With P. Dunnill) Biochemical reactors. Process Biochem. 6, 29-32 Contents of reference: offprint, correspondence, notes and drafts Lilly’s folder divided into four for ease of (50) 1971 (With P. Dunnill) The problems of large-scale extraction and purification of microbial enzymes. J. Gen. Microbiol. 65, ix Offprint only. (With a (51) 1971 glass as chromatography of enzymes. 242,659-661 solid P.J. Robinson and P. support for immobilisation or Dunnill) Porous affinity Acta Biophys. Biochim. Contents of Lilly’s folder: offprint, correspondence, draft D.87-D.88 folder divided into two for ease of Contents of reference: offprint, drafts. Lilly's Contents of Lilly’s folder: offprint, correspondence. (52) 1971 (With J.R. Wykes and P. Dunnill) Immobilisation of a-amylase by attachment to soluble support materials. Biochim. Biophys. Acta 250, 522-529. (53) 1972 (With K. Balasingham, D. Warburton and P. Dunnill) The isolation and kinetics of penicillin amidase from Escherichia coli. Biochim. Biophys. Acta 276, 250- 256. of immobilised (54) 1972 (With P.J. Robinson and P. affecting galactosidase. Biochim. Biophys. Acta 282,28-35 (55) 1972 (With D. Warburton, K. Balasingham and P. Dunnill) Contents of reference: offprint, correspondence, drafts, etc. folder divided Dunnill) Factors R- of into two for ease of chromatography The preparation and kinetics scale-up of affinity D.92-D.93 D.90-D.91 Lilly's M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 penicillin amidase from Escherichia coli. Biochim. Biophys. Acta 284, 278-284 Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into two for ease of (With of 1972 (56) preparation derivative active as 286, 260-268 J.R. soluble Wykes and high The NAD a cofactor. Biochim. Biophys. Acta P. molecular Dunnill) weight 1972-1973 Contents of Lilly's folder: offprint, correspondence, draft. D.95-D.98 (57) 1972 (With J.A. Currie and P. Dunnill) Release of protein from bakers’ yeast, Saccharomyces cerevisiae by disruption in an industrial agitator mill. Biotechnol. Bioeng. 14, 725-736 Contents of reference: offprint, drafts. Lilly's folder divided into four for ease of Dunnill) Engineering of 1972 (With P. D.99-D.100 Lilly's folder divided into two for ease of Contents of Lilly’s folder: offprint, correspondence, drafts. Contents of reference: offprint, correspondence, drafts. (59) aspects enzyme reactors. Biotechnol. Bioeng. Symp. 3, 221-227 (58) 1972 (With P. Dunnill) Continuous enzyme isolation. Biotechnol. Bioeng. Symp. 3, 97-113 1971-1972 (60) 1972 (With P.P. Gray and P. Dunnill) Kinetics of f- galactosidase mutant of Escherichia coli. (61) 1972 The use of immobilised enzymes in reactors. Proc. Conf. on Solid Phase Proteins. pp. 75-77. Seattle: Batelle Institute Contents of Lilly's folder: offprint, draft, etc. J. Ferment. Technol. 50, 381-387 Offprint only. production by a constitutive M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (62) 1972 (With P.P. Gray and P. Dunnill) The continuous- flow isolation of enzymes. Proc. IV I.F.S. Conf. pp. 347 - 351. Japan: Society of Fermentation Technology Contents of Lilly’s folder: off-print, correspondence, drafts. (63) 1972 (With K. Balasingham, D. Warburton and P. IV LF.S. Dunnill) Immobilised enzyme reactors. Conf. Fermentation Technology 379-381. Society Japan: Proc. pp. of Contents of Lilly's folder: offprint, drafts. (64) 1972 The use of immobilised enzymes in the food industry. Proc. Int. Symp. Conversion and Manufacture of Foodstuffs by Microorganisms. pp. 65-74. Tokyo: Saikon Pub. Co. Ltd Offprint only. Contents of Lilly’s folder: offprint, correspondence, draft. (66) 1973 (With G. Street, P. Dunnill and V.A.S. Glover) Large scale isolation of choline acetyltransferase from ox brains. Biotechnol. Bioeng. 15, 271-283 (65) 1973 (With D. Warburton and P. Dunnill) Conversion a batch of benzylpenicillin to 6-aminopenicillanic acid in reactor and continuous feed-stirred tank reactor using immobilised penicillin amidase. Biotechnol. Bioeng. |5, 13- Zo properties of magnetic supports in relation to immobilised (67) 1973 (With P.P. Gray and P. Dunnill) The clarification of mechanically disrupted yeast suspensions by rotary vacuum precoat filtration. Biotechnol. Bioeng. 15, 309-320 Contents of Lilly’s folder: offprint, correspondence, draft. Contents of Lilly's folder: offprint, correspondence, draft. Robinson and Dunnill) The P. (68) 1973 (With P.J. M.D. Lilly NCUACS 150/7/06 D.113-D.114 Publications, D.1-D.366 enzyme reactors. Biotechnol. Bioeng. 15, 603-606 Contents of Lilly's folder: offprint, correspondence, drafts. (69) 1973 (With P.P. Gray and P. Dunnill) The effect of controlled feeding of glycerol on -galactoside production by Escherichia coli in batch culture. Biotechnol. Bioeng. 15, 1179-1188 Contents of Lilly's folder: offprint, correspondence, drafts. 1973 (With (70) The bioengineering of immobilised enzymes. Biochimie 55, 985- 990 Dunnill) O'Neill S.P. and P. Contents of Lilly's folder: offprint, correspondence, drafts. 1973 (With (71) precipitation of Saccharomyces Biochim. Biophys. Acta 317, 505-516 P.R. enzymes cerevisiae from by Foster and Dunnill) extracts The P. cell of polyethyleneglycol. B. Spencer). pp. Lilly’s 1973-1974 D.115-D.116 folder divided into two for ease of B.C. Buckland, W. Richmond and Contents of reference: offprint, correspondence, drafts. Lilly's folder divided Contents of reference: offprint, correspondence, drafts. (72) 1974 (With P. Dunnill) The large-scale isolation of intracellular microbial enzymes: cholesterol oxidase from Nocardia. In Industrial Aspects of Biochemistry (ed. 65-79. Amsterdam: FEBS 396-398 (73) 1974 (With D.L. Regan and P. Dunnill) Immobilized enzyme reactor stability: attrition of the support material. Biotechnol. Bioeng. 16, 333-343 Dunnill) Teaching and research in The Chemical Engineer 286, (74) 1974 (With biochemical engineering. Contents of Lilly’s folder: offprint, correspondence, draft. into two for ease of D.118-D.119 P. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into two for ease of P. 1974 (With (75) Dunnill) Recent developments in enzyme isolation processes. In Enzyme Engineering vol. 2, pp. 43-45. New York: Plenum Press E.K. Pye and L.B. Wingard Jr.), (ed. 1973-1974 Contents of Lilly's folder: offprint, correspondence, drafts. D.121-D.122 (76) 1974 (With D.L. Regan and P. Dunhill) Well-mixed immobilized enzyme reactors. In Enzyme Engineering, vol. 2, (ed. E.K. Pye and L.B. Wingard Jr.), pp. 245-251. New York: Plenum Press 1973-1974 Contents of reference: off-print, correspondence, drafts. Lilly's folder divided into two for ease of D.123-D.124 Lilly's folder divided into two for ease of (77) Technik 46, 684-689 1974 Biochemische reaktoren. Chemie. Ingenieur Contents of reference: offprint, correspondence, drafts. folder divided Lilly's (78) 1974 (With P. Dunnill) Purification of enzymes using magnetic bio-affinity. Biotechnol. Bioeng. 16, 981- 990 Contents of into two for ease of reference: offprint, correspondence, English and German versions etc. 1973-1974 (79) 1974 (With D.L. Regan and P. Dunnill) Influence of intraparticle diffusional limitation on the observed kinetics of design. and Biotechnol. Bioeng. 16, 1081-1093 (80) M.A. Wheatley, J.-C. Lanson and P. Dunnill) Pilot scale affinity chromatography: Lilly's folder divided into three for ease of offprint, correspondence, drafts, manuscript Contents of reference: working. 1974 (With P.J. Robinson, immobilized enzymes on catalyst D.125-D.126 D.127-D.129 D.130-D.132 M.D. Lilly NCUACS 150/7/06 D.133-D.135 D.136-D.138 Publications, D.1-D.366 purification 1103-1112 of B-galactosidase. Biotechnol. Bioeng. 16, Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into three for ease of J.R. Wykes and P. Dunnill) Cofactor (81) 1975 (With recycling in an enzyme reactor. A comparison using free and and immobilized NAD. Biotechnol. Bioeng. 17, 51-68 dehydrogenases immobilized with free 1974-1975 Contents of reference: offprint, correspondence, drafts. Lilly’s folder divided into three for ease of B.C. 1975 (With Buckland and (82) The enzymatic transformation of water-insoluble reactants in non-aqueous to cholest-4-ene-3-one by a Nocardia sp. Biotechnol. Bioeng. 17, 815-826 Conversion cholesterol solvents. Dunnill) of P. Contents of reference: offprint, correspondence, drafts. Lilly’s folder divided into three for ease of of 1975 179-207. D.142-D.146 D.139-D.141 D.I.C. Wang), Lilly’s folder divided into three for ease of Contents of reference: photocopy of published text, letter to publisher, drafts. (83) 1975 (With P. Dunnill) Protein extraction and recovery from microbial cells. S.R. Tannenbaum and Cambridge Mass.: MIT Press In Single Cell Protein || (eds. 1974-1975 (84) Affinity chromatography of enzyme cofactors: the separation of NAD on immobilised dehydrogenase columns. Biochim. Biophys. Acta, 397, 277-287 (85) synthesis of B-galactosidase by constitutive regulatory in Escherichia culture. J. Gen. Microbiol. 89, 221-228 Contents of reference: offprint, correspondence, drafts. Lilly's folder divided Dunnill) The and other chemostat C.J.L. MacLeod and for ease of 1975 (With D.147-D.149 Dunnill) mutants (With into five coli P. K. Das and P. M.D. Lilly NCUACS 150/7/06 D.152-D.159 Publications, D.1-D.366 Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into three for ease of (86) 1975 (With Dunnill) Magnetic particles as supports in immobilised enzyme reactor. /EEE Trans. on Magnetics, MAG-11 (5), 1573-1575. P.A. Munro and P. Contents of Lilly’s folder: photoocpy of published text. 1975 (With (87) teaching: Process Biochem. 10, 17-20 foundation P. a for Dunnill) Biochemical the biological engineering industries. Offprint only. (88) 1976 (With P.R. Foster and P. Dunnill) The kinetics of protein of yeast enzymes by ammonium sulfate. Biotechnol. Bioeng. 18, 545-580 precipitation salting-out: 1975-1976 P. Lilly's 1975-1976 1976 (With B.C. D.160-D.161 Buckland and into two for ease of Lilly’s folder divided into eight for ease of Contents of reference: offprint, correspondence, drafts. Contents of reference: offprint, correspondence, drafts. folder divided (89) kinetics rhodochrous. Biotechnol. Bioeng. 18, 601-621 Dunnill) The of cholesterol oxidase synthesis by Nocardia (90) 1976 (With Z. Duvnjak) The immobilization of glucose oxidase to manganese oxide. Biotechnol. Bioeng. 18, 7- 739 1975-1976 (91) The deacylation of benzylpenicillin by immobilized enzyme. In Proc. p. 301. Berlin: Verlag Versuchs und Lehranstalt Contents of Lilly’s folder: offprint, correspondence, draft. Vth Int. Fermentation Symp. (ed. H. Dellweg), Smith and Offprint only. 1976 (With S. W. P.Dunnill) M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (92) 1976 (With P.S.J. Cheetham, D.J. Lewis, J. Yates and P. Dunniii) Conversion of choiesteroi to cholestenone, androstenedione and androstadienedione. In Proc. Vth Int. Fermentation Symp. (ed. Berlin: Verlag Versuchs und Lehranstalt Dellweg), 327. H. p. Offprint only. 1976 (With (93) P. engineering. postgraduate teaching H. Dellweg), Proc. 461. Berlin: Verlag Versuchs und Lehranstalt of biochemical Int. Fermentation Symp. (ed. Undergraduate Dunnill) Vth and In p. Offprint only. D.166-D.167 (94) 1976 Enzymes immobilized to cellulose. In Methods in Enzymology XLIV: K. Mosbach), pp. 46-53. New York: Academic Press Immobilized Enzymes (ed. Contents of reference: correspondence, drafts. Lilly’s folder divided photocopy of into two for ease of published version, Lilly’s photocopy of five 1974-1976 folder divided D.168-D.172 into published for ease of version, Contents of reference: correspondence, drafts. (95) 1976 (With P. Dunnill) Immobilized-enzyme reactors. In Methods in Enzymology XLIV: Immobilized Enzymes (ed. K. Mosbach) pp.717-738. New York: Academic Press 1987 (97) 1977 A comparison of cells and enzymes as industrial catalysts. In Biotechnological Applications of Proteins and Enzymes. pp.127-39. (ed. A. Bohak and N. Sharon). New York: Academic Press (96) 1977 (With P.A. Munro and P. Dunnill) Nonporous studies with magnetic materials as enzyme supports: immobilized chymotrypsin. Biotechnol. Bioeng. 19, 101- 124 Contents of Lilly’s folder: offprint, correspondence, draft. Contents of Lilly's folder: offprint, correspondence, draft. 1976-1977, 1976-1977 M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 D.175-D.176 (98) 1978 (With P.S.J. Cheetham and P. Dunnill) Mass transfer problems with immobilized oxidases. In Enzyme Engineering 3 (ed. E.K. Pye and H.H. Weetall). pp. 72-78. New York: Plenum Press 1975, 1978 Lilly's Contents of folder divided into two for ease of reference: offprint, correspondence, drafts including draft for talk in Portland, Oregon in 1975. D.177-D.178 and (99) 1978 (With J.J. Higgins. D.J. Lewis. W.H. Daly. F.G. Mosqueira unit operations involved in the continuous flow isolation of B- galactosidase from Escherichia coli. Biotechnol. Bioeng. 20, 159-182 Investigation Dunnill) the of P. Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into two for ease of 1977-1978 1979 Immobilized enzyme reactors. |In Proc. ‘1st. (100) European Dechema Monograph 82. pp.165-180. Frankfurt am Main: Verlag Chemie Biotechnology Congress on reference: Offprint only. D.180-D.184 correspondence, Contents of Lilly's folder so inscribed divided into five for ease drafts, reviews, etc (101)1979 (With D.I.C. Wang, C.L. Cooney, A.L. Demain. P. Dunnill and A.E. Humphrey) Fermentation and enzyme technology. New York: Wiley. 1975-1981 (103) 1979 Production of intracellular microbial enzymes. In Appl. Biochem. Bioeng. Vol 2. (ed. L.B. Wingard Jr.. E. Katchalski-Katzir and L. Goldstein). pp.1-26. New York: Academic Press. (102) benzylpenicillin continuous four-stage Bioeng. 21, 1057-1073 S W Carleysmith) Deacylation in of a Biotechnol. by immobilized D.186-D.187 Offprint only. stirred-tank penicillin acylase 1979 (With of offprint, reactor. Lilly M.D. NCUACS 150/7/06 Publications, D.1-D.366 Contents of reference Lilly's folder divided into two for ease of (104) 1979 (With A.W. Nienow) Power drawn by multiple impellers in sparged agitated vessels. Biotechnol. Bioeng. 21, 2341-2345 Offprint only. (With of the Dunnill) (105) 1980 Optimization a- hydroxylase by Rhizopus nigricans. Biotechnol. Bioeng. 22, 555-570 W.H. production of progesterone II Hanisch and P. Offprint only. (106) 1980 (With S. W. Carleysmith and P. Dunnill) Kinetic behaviour of immobilized penicillin acylase. Biotechnol. Bioeng. 22, 735-756. 1980 (With P.S.J. Offprint only Offprint only. (107) 1980 (With S.W. Carleysmith and M.B.L. Eames) Staining method for determination of the penetration of immobilized enzyme into a porous support. Biotechnol. Bioeng. 22, 957-967 Offprint only. (109) Dunnill) Deacylation of benzylpenicillin by immobilized penicillin acylase. Biochimie 62, 317-321 (108) Extraction rhodochrous. Enzyme Microb. Technol. 2, 201-205 Dunnill) Nocardia Carleysmith and Cheetham and Offprint only. 1980 (With S. W. of cholesterol oxidase from P. P. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 198 0 (With J.M.C. (110) Duarte) The use of free and immobilized cells in the presence of organic solvents: the oxidation In Enzyme Engineering 5 (ed. H.H. Weetall and G.P. Royer). pp. 363-367. New York: Plenum Press rhodocrous. cholesterol Nocardia by of Offprint only. (111) 1981 (With J.A. Asenjo and P. Dunnill) Production of yeast-lytic enzymes by Cytophaga batch culture. Biotechnol. Bioeng. 23, 97-109 species in Offprint only. (112) 1981 (With F.G. Mosqueira. J.J. Higgins and P. Dunnill) Characteristics of mechanically disrupted bakers’ yeast in relation to its separation in industrial centrifuges. Biotechnol. Bioeng. 23, 335-343 Offprint only. 1981 stirred tank (With Rhizopus (With cells Offprint only. Dunnill) Use of a- 23. for the Bioeng. P.A. Munro and reactors (113) 1981 immobilized nigricans hydroxylation of progesterone. Biotechnol. 345-354 I.S. Maddox and P. of P. Dunnill) Casein (114) hydrolysis in using chymotrypsin immobilized on magnetic supports. Biotechnol. Bioeng. 23, 677-689 Offprint only. (115) 1982 (With P.S.J. Cheetham and P. Dunnill) The characterization and interconversion of three forms of cholesterol oxidase extracted from Nocardia rhodochrous. Biochem J. 201, 515-521 Offprint only. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (116) 1982 (With F. Vardar) The measurement of oxygen- transfer coefficients in fermentors by frequency response Contents of Lilly’s folder: offprint, draft. (117) 1982 (With F. Vardar) Effect of cycling dissolved oxygen concentrations on product formation in penicillin fermentations. European J. Biotechnol. 14, 203-211 Microbiol. Appl. Offprint only. (118) 1982 (With N.M. Fish and D.J. Allenby) Oxidation of n-alkanes: growth of Pseudomonas putida. European J. Appl. Microbiol. Biotechnol. 14, 259-262 1982 Two-liquid-phase biocatalytic (119) Chem. Tech. Biotechnol. 32,162-169 reactions. J. Offprint only. Offprint only. (120) 1982 (With B. McDougall and P. Dunnill) Enzymic acylation of 6-aminopenicillanic acid. Enzyme Microb. Technol. 4, 114-115 (121) 1982 (With A.T. Bull and G. Holt) Biotechnology - International Trends and Perspectives. OECD, Paris. (also published in French. German. Greek. Japanese. Spanish and Turkish) Offprint only. (122) 1983 Two-liquid phase biocatalytic reactors. Trans. R. Soc. Lond. 300, 391-398 Duplicated typescript only. Phil. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (123) 1983 Problems in process scale-up. In Bioactive Microbial Products 2. L.J. Nisbet). pp. 79-89. London: Academic Press D.J. Winstanley and (ed. Offprint only. (124) 1983 (With N.M. Fish. S. Harbron and D.J. Allenby) Oxidation of n-alkanes: isolation of alkane hydroxylase from Pseudomonasputida. European J. Appl. Microbiol. Biotechnol. 17, 57-63 Offprint only. 1984 (With between (125) fermentation and protein recovery. Biotechnology 2, 623- 628 Interactions Fish) N.M. Contents of Lilly's folder: offprint, draft. Kloosterman IV) Effect 1983-1984 1983-1984 1984 (With J. D.214-Bi242 of fats: factors interesterification folder divided into two for ease of Contents of referemce: offprint, correspondence, drafts. Lilly's Contents of Lilly’s folder: offprint, draft, covering letter. (126) of supersaturated aqueous hydrocortisone concentrations on A'-dehydrogenase activity. Enzyme Microb. Technol. 4, 113-116 (127) 1984 (With R.A. Wisdom. P. Dunnill and A. Macrae) Enzymic influencing choice of support for immobilized lipase. Enzyme Microb. Technol. 6, 443-446 1984-1985 (128) 1985 (With J. Kloosterman IV) An airlift loop reactor for the transformation of steroids by immobilized cells. Biotechnol. Lett. 7, 25-30 (129) 1985 (With T. Keshavarz and P.H. Clarke) Stability of Gen. Microbiol. 131, 1193-1203 a catabolic plasmid in continuous culture. Contents of Lilly’s folder: offprint, correspondence, draft. D.214-D.219 J. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Contents of Lilly's folder divided into six for ease of erence: offprint, correspondence, drafts. (130) 1985 (With J.M.C. Duarte) Cholesterol degradation by in solvents. Annals N. Y. Acad. Sci. 434, 573-576 polymer-entrapped Nocardia organic Contents of Lilly’s folder: offprint, draft. D.221-D.222 (131) 1985 (With J. Kloosterman 1 V) Maintenance and operational stability of immobilized Arthrobacter simplex for the A' dehydrogenation of steroids. Enzyme Microb. Technol. 7, 377-382 Contents of reference: offprint, correspondence, drafts. folder divided Lilly's into two for ease of D.223-D.225 vol. IV pp. Contents of Lilly's folder: offprint, draft. Lilly's folder divided into three for ease of Contents of reference: offprint, correspondence, drafts. (132) 1985 (With R.A. Wisdom and P. Dunnill) Enzymic interesterification of fats: the effect of non-lipase material on immobilized enzyme activity. Enzyme Microb. Technol. 7, 567-572 (133) 1985 (With S. Harbron and T.J. Narendranathan) Effects of mass transfer on the kinetic behaviour of two- liquid phase biocatalytic reactions. Proc. 3rd. European Congress Biotechnol. 369-374. Weinheim: VCh. 1985-1986 .M. Woodley) Biocatalytic reactions (134) 1985 (With J involving In Biocatalysts in Organic Syntheses (ed. J. Tramper, H.C. van der Plas and P. pp. 179-192. Amsterdam: Elsevier Contents of Lilly’s folder: offprint, correspondence, draft. water-insoluble organic compounds. Linko), M.D. Lilly NCUACS 150/7/06 D.228-D.232 Publications, D.1-D.366 I.K. 1986 (With Drozd) (135) Stereospecific hydrolysis of d,l-menthyl acetate by Bacillus Subiilis: mass transfer reaction interactions in liquid- liquid system. Enzyme Microb. Technol. 8, 53-57 Brookes J.W. and a Contents of reference: offprint, correspondence, drafts. folder divided Lilly's into five for ease of (136) 1986 (With S. Harbron and B. W. Smith) Two-liquid phase by Pseudomonas putida. Enzyme Microb. Technol. 8, 85-88 1,7-octadiene biocatalysis: epoxidation of 1985-1986 Contents of Lilly’s folder: offprint, correspondence, draft. 1986 Recommendations (137) to describe the metabolic behaviour of immobilised cells. Enzyme Microb. Technol. 8, 315 nomenclature for Contents of Lilly's folder: offprint, correspondence, draft. 3 (ed. J.D. P.J. using Lilly's Bailey and calcium Stowell, alginate 1985-1986 prednisolone D.235-D.236 into two for ease of Contents of Lilly’s folder: offprint, correspondence, draft. Contents of reference: offprint, correspondence, drafts. folder divided (138) 1986 (With J. Kloosterman IV) Pilot plant production of immobilized Arthrobacter simplex. Biotechnol. Bioeng. 28,1390-1395 (139) 1986 Concluding Remarks In Bioactive Metabolic Products DJ. Winstanley), pp. 231-233. London: Academic Press 1984-1987 (140) 1986 Developments in industrial biocatalysis. Proc. 7th. G. Tregear), Australian Melbourne: Biotechnology Conference Committee (141) 1987 (With S. Harbron and T.J. Narendranathan) Two-liquid phase biocatalytic In Methods in Enzymology 136C: Immobilized Enzymes and Cells. (ed. Biotechnology 83-88. Australian pp. Offprint only Conference. reactors. (ed. 7th M.D. Lilly NCUACS 150/7/06 D.240-D.241 Publications, D.1-D.366 K. Mosbach), pp. 138-149. New York: Academic Press Contents of Liliy’s foider: offprint, correspondence, drafts. (142) 1987 (With I.K. Brookes and J.W. Drozd) Use of stereospecific immobilized hydrolysis Microb. Technol. 9, 217-220 d,l-menthyl Enzyme acetate. Bacillus subtilis the for of Contents of reference: offprint, correspondence, drafts. folder divided Lilly's into two for ease of (143) 1987 (With R.A. Wisdom and P. Dunnill) Enzymic interesterification of fats: laboratory and pilot-scale studies with Rhizopus = arrhizus. from Biotechnol. Bioeng. 29, 1081-1085 immobilized lipase Contents of Lilly’s folder: offprint, correspondence, draft. 1985-1987 1986-1987 1987 (With P. Dunnill) Use of simplex. Appl. Microbiol. Biotechnol. 1986-1987 D.244-D.245 Contents of Lilly's folder: offprint, correspondence, draft. Contents of reference: offprint, correspondence, drafts. folder divided (145) 1987 (With A. Freeman) The effect of water-miscible solvents on A'-dehydrogenase activity of free and PAAH- entrapped A. 25, 495-501 (144) immobilized biocatalysts for conversions of water-insoluble reactants: interesterification of fats In Enzyme Engineering VIll (ed. A.L. Laskin, K. Mosbach, D. Thomas and L.B. Wingard), Annals N.Y. Acad. Sci. 501, 113-118 conversions (146) 1987 Culture systems and bioreactors. In Modelling and Control of Fermentation Processes (ed. J.R. Leigh), pp. 87-96. London: Peter Peregrinus Photocopy of published text only. into two for ease of (147) Williams Woodley) Biological Hocknull, Brazier, 1987 (With A.J. and J.M. Lilly's M.D. A.C. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 water-insoluble involving Biocatalysis in Organic Media (ed. and M.D. Liliy), pp. 3-17. Amsterdam: Elsevier organic compounds. In C. Laane, J. Tramper Offprint only. (148) 1987 (With M.D. Hocknull) The A'-dehydrogenation of hydrocortisone by Arthrobacter simplex in organic- aqueous two-liquid phase environments. In Biocatalysis in Organic Media (ed. C. Laane and J. Tramper), pp. 393- 398. Amsterdam: Elsevier (149) 1987 (With A.C. Williams, J.M. Woodley and P. Ellis) Denaturation and inhibition studies in a two-liquid phase biocatalytic reaction: the hydrolysis of menthy! acetate by pig liver esterase. In Biocatalysis in Organic Media (ed. C. Laane and J. Tramper), pp. 399-404. Amsterdam: Elsevier Offprint only. with Sci. Ison and on C. Rice) Microbial Offprint only. Dunnill) P. enzyme 1988 (With A.P. concentration Contents of Lilly's folder: offprint, correspondence, draft. Effect of (151) solvent catalysed interesterification of fats. Enzyme Microb. Technol. 10, 47- 51 (150) 1987 (With D.C. Smith, A.T. Bull, G. Holt, C. Christy specific and halogenation reference to chloroperoxidase. ASEAN J. Technol. Develop. 4 (2), 29-43 in- (152) 1988 Biochemical Engineering - society: 121-134 Its contribution to Hartley Lecture. Science and Public Affairs 3, Offprints from Science and Public Affairs and alternative publication in Measurement + Control, May 1988. (153) 1988 (With M.D. Hocknull) Stability of the steroid A’- dehydrogenation Arthrobacter system of simplex M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 organic Enzyme Microb. Technol. 10, 669-674 solvent-water two-liquid phase environments. Contents of Lilly's folder: offprint, correspondence, draft. 1988 The training in (154) Proceedings Biotechnology Symposium (ed. G. Durand, L. Bobichon and J. Florent), p. 1254. Paris: Societie Francaise de Microbiologie vol. 2, of biochemical engineers. International 8th of Offprint only. (155) 1989 Biochemical engineering for flavour and food production. In Biotechnology Challenges for the Flavour and International Conference Symposium in Williamsburg USA. (ed. R.C. Lindsay and B.J. Willis), pp. 55-63. London: Elsevier Proceedings Industry. Food of Contents of Lily's folder: photocopy of published version and draft. Offprint only. (156) 1989 (With A.N.C. Weir, C. Bucke, G. Holt and A.T. Bull) A high-performance liquid chromatography method for simultaneous assay of diaminopimelate epimerase and decarboxylase. Analytical Biochemistry 180, 298-302 (157) 1989 (With GA. Dervakos, J.M. Woodley, E.T. Keravnou and J. Washbrook) Development of a KBS for biotransformation process design. /. Chem. E. Symposium Series No 114, 283-291 1988-1989 (158) 1989 (With T. Keshavarz, E. Walker, R. Eglin, G. Lilley, G. Holt and A.T. Bull) Immobilization of Penicillium chrysogenum: spore growth on Microbiol. Biotechnol. 30, 487-491 Contents of Lilly's folder correspondence, drafts. Contents of Lilly's folder: Celite. Appi. M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 1989 (159) (With Biotransformations between and Biotechnol. Letters 11, 807-810 Gram-positive AJ. in organic Harrop and M.D. a_ solvents: Gram-negative Hocknull) difference bacteria. Contents of Lilly's folder: offprint, correspondence, draft. A.P. 1990 (With (160) Dunnill) Enzymic interesterification of fats: immobilization and immunogold localization of lipase on ion exchange resins. Biocatalysis, 3, 329-342 Ison and P. 1989-1990 Contents of Lilly's folder: off-print, correspondence, draft. (161) 1990 (With A.J. Brazier and A.B. Herbert) Toluene cis-glycol synthesis by Pseudomonas putida; kinetic data for reactor evaluation. Enzyme Microb. Technol. 12, 90-94 1988-1990 Contents of Lilly's folder: offprint, correspondence, draft. pig for 1988-1990 Bacillus subtilis as D.263-D.264 Contents of Lilly’s folder: offprint, Narendranathan) A comparison of and catalysts (163) 1990 (With J.J. Smith and R. Fox) The effect of agitation on the morphology and penicillin production of Penicillium chrysogenum. Biotechnol. Bioeng. 35, 1011- 1023 (162) 1990 (With A.C. Williams, J.M. Woodley, P.A. Ellis liver and T.J. esterase the hydrolysis of menthyl acetate in stirred two-liquid phase reactors. Enzyme Microb. Technol. 12, 260-265 1988-1990 (164) 1990 (With T. Keshavarz, C. Bucke, A.T. Bull and G. Holt) Penicillium chrysogenum. |In Physiology of Immobilized Cells (ed. J.A.M. de Bont, J. Visser, B. Mattiasson and J. Tramper), pp. 369-375. Amsterdam: Elsevier into two for ease of manuscript Contents of reference: working. folder divided correspondence, Lilly's offprint, Offprint only. of immobilised Pilot-scale studies draft, M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 M. 1990 (With (165) immobilised solvent/aqueous’ Microbiol. Biotechnol. 33, 148-153 Arthrobacter two-liquid simpiex phase Hocknull) The use of in free and organic Appl. reactors. 1989-1990 Contents of Lilly's folder: offprint, correspondence, draft, figures. (166) 1990 (With J.M. Woodley) Extractive biocatalysis: the use of two-liquid phase biocatalytic reactors to assist product recovery. Chem. Eng. Sci. 45, 2391-2396 Offprint only. phase (167) 1990 (With G.A. Dervakos and J.M. Woodley) Two- liquid In Opportunities in Biotransformations (ed. L.G. Copping, R.E. Martin, J.A. Pickett, C. Bucke and A. W. Bunch), pp. 5-16. London: Elsevier biocatalysis: choice phase ratio. of G. A.T. Bull) The Eglin, Holt and in an_ airlift reactor. operation D.269-D.270 into two for ease of Contents of reference: offprint, correspondence, drafts. Lilly’s folder divided Photocopy of published text only. (168) 1990 (With T. Keshavarz, R. Bucke, immobilization of Penicillium chrysogenum: batch continuous Bioeng. 36, 763-770 E. Walker, C. large-scale and Biotechnol. Bioeng. 37, 133-140 (169) 1990 (With A.R. Russell and C.R. Thomas) The hydrodynamics of a pilot-scale airlift fermenter. Proc. 5th European C. pp. 809-812. Christiansen, L. Munct and J. Villadsen), Copenhagen: Munksgaard. (170) 1991 (With J.M. Woodley and A.J. Brazier) Lewis cell studies to determine reactor design data for two-liquid phase Biotechnol. Photocopy of published text only. D.272-D.273 Biotechnolog. reactions. Congress bacterial and enzymic (ed. on_ M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Lilly’s Contents of into two for ease of reference: offprint, correspondence, referee’s comment, draft, figures. folder divided (171) (With J.M. Woodley and A.J. Harrop) The impact of biocatalyst selection on the design of aqueous-organic biophase biocatalytic processes. Enzyme Engineering, 10, 191-200 Offprint only. (172) 1991 (With J. M. Woodley and P.J. Cunnah) Stirred tank two-liquid phase biocatalytic reactor studies: kinetics, evaluation and modelling of transfer. Biocatalysis, 5, 1-12 1991 (With K. Gbewonyo and (173) Buckland) Development of a large-scale continuous substrate feed process by Nocardia sp. Biotech. Bioeng. 37, 1101-1107 biotransformation Simvastatin B.C. the for of Offprint only. Offprint only. (174) 1991 (With M.W. Adiard, B.M. Gordon, C. Bucke, A.T. Bull and G. Holt) A HPLC procedure for monitoring penicillin G fermentations. Biotechnol. Techniques 5, 121- 126 (175) 1992 (With H.P. Packer and E. Keshavarz-Moore) The estimation of cell volume and biomass of Penicillium chrysogenum using image analysis. Biotechnol. Bioeng. 39, 384-391 1991-1992 (176) 1992 (With F. Villesid) Influence of dissolved oxygen tension on the synthesis of catechol, 1,2-dioxygenase by Pseudomonas putida. Enzyme Microb. Technol. 14, 561- 565 Contents of into two for ease of reference: offprint, correspondence, referees’ comments, Contents of Lilly's folder: offprint, correspondence. folder divided D.279-D.280 Lilly's M.D. Lilly NCUACS 150/7/06 D.281-D.282 Publications, D.1-D.366 A.J. 1992 (With (177) Production putida Microb. Technol. 14, 725-730 of naphthalene-cis-glycol the presence of organic Harrop in and J.M. Woodley) by Pseudomonas solvents. Enzyme 1991-1992 Lilly's Contents of for ease of reference: offprint, correspondence, referees’ comments, draft. folder divided into two 1992 Biochemical (178) its contribution to the biological industries. Trans. |. Chem. E. 72C, 3-6 engineering research: Contents of Lilly's folder: offprint, draft. (179) 1992 Design and operation of biotransformation processes. Recent Advances in Biotechnology In NATO ASI Series E. Vol. 210. (ed. F. Vardar Sukan and S. Suha Sukan), pp. 47-68 In Offprint only. Offprint only. D.286-D.287 phase biocatalysis. (180) 1992 (With J.M. Woodley) Process engineering of two-liquid Biocatalysis in Non- Conventional Media (ed. J. Tramper, M.H. Vermue, A.H. Beeftink and U. von Stocker) pp. 147-154. Amsterdam: Elsevier (182) 1992 (With A.P. Ison and P. Ayazi Shamlou) The influence of the physical environment in fermenters on antibiotic production by microorganisms. In Harnessing Biotechnology for the 21st Century (ed. M.R. Ladisch and A. Bosse), pp. 219-222. Washington: American Chemical Society Contents of into two for ease of reference: typescript of paper and correspondence and papers re 9th International Biotechnology Symposium at which the paper was delivered. folder divided Lilly’s M.D. Lilly NCUACS 150/7/06 D.288-D.291 D.292-D.294 Publications, D.1-D.366 1993 (184) overview. Stephanopoulos). pp.7-22. Weinheim: VCH Biotechnology (With in Buckland) Voi. B. C Fermentation: 3). (ea: an G. 1982-1993 Lilly's folder divided into Contents of for ease of reference: photocopy of published text, correspondence, manuscript notes, background papers. four (185) 1993 (With H.Y. Makiagansar, P. Ayazi Shamlou and C.R. Thomas). The influence of mechanical forces on the morphology and penicillin production of Penicillium chrysogenum. Bioprocess Engineering 9, 83-90 Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into three for ease of (186) 1993 (With G.R. Hobbs, N.J. Turner, J.M. Ward, A.J. Willets and J.M. Woodley) Enzyme catalysed carbon- carbon from of Escherichia coli. Perkin Transactions |}, 165-166 J. Chem. Soc. transketolase formation: bond use R. of 1992-1993 1993 (With Offprint only. Contents of Lilly’s folder: offprint, correspondence, draft. (187) 1993 (With A. Freeman and J.M. Woodley) In situ product removal as a tool for bioprocessing - an overview. Biotechnology Il, 1007-1012 reference: offprints, correspondence, draft. J.M. Woodley) The (188) characterization to fluorocatechol by Pseudomonas putida leading to large scale bioreactor design. |. Chem. E. Research Event, pp.51-54. Rugby: |.Chem. E. Lilly’s folder divided into three for ease of 1994 Advances in (189) Chem. Eng. Sci. 49 C, 151-159. (Danckwerts Lecture) biotransformation Lynch fluorobenzene Offprint only. D.298-D.300 Contents of 1993-1994 processes. oxidation 1993 In Proc. and M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (190) 1994 (With N. Rosen, J.M. Woodley and A.T. Bull) Enzymatic dehaiogenation haio- alcohols. Proc. 1994 |. Chem. E. Research Event, pp. 91- 93. Rugby: |. Chem. E. of haio-aikanes and Offprint only. (191) 1994 (With G.R. Hobbs, C. French, M. Gyamerah, G. Morris, N.J. Turner, J.M. Ward, A.J. Willetts and J.M. Woodley). Development of a process for transketolase catalysed carbon-carbon bond formation. Proc. 1994 |. Chem. E. Research Event, pp.247-249. Rugby: |. Chem. 3. Offprint only. (192) 1994 (With G.R. Hobbs., N.J. Turner, J.M. Ward and J.M. Woodley) Transketolase production for use as a catalyst for carbon-carbon bond formation. Proc. 1994 |. Chem. E..Research Event, pp. 289-291. Rugby: |. Chem. E. Offprint only. Contents of Lilly’s folder: offprint, figures, correspondence, referees’ comments (193) 1994 (With A.B. Russell and C.R. Thomas) The influence of vessel height and top-section size the hydrodynamic characteristics of airlift fermenters. Biotech. Bioeng. 43, 69-76 on Contents of Lilly’s folder: offprint, correspondence, draft. (194) J.M. Liddell) The production of Pseudomonas putida for the hydroxylation of toluene to its cis-glycol. Appi. Microbiol. Biotechnol. 41, 495-499 (195) 1994 (With P. Ayazil Shamlou, D.J. Pollard and A.P. Ison) Gas holdup and liquid circulation rate in concentric- tube airlift bioreactors. Chem. Eng. Sci. 49, 303-312 Contents of Lilly's folder: offprint, draft. 1994 (With C.J. Hack, J.M. Woodley and M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (196) 1994 (With P. Ayazi Shamlou, H. Makiagamsar, A.P. ison and C.R. Thomas) Turbulent breakage of filamentous microorganisms in submerged culture in mechanically stirred bioreactors. Chem. Eng. Sci. 49, 2621-2631 Offprint only. M.E. 1994 (With S.W. (197) Carleysmith and lipids during Streptomycete fermentations. Trans. |. Chem. E. 72 C, 14-16 J. Edwards) The utilisation Cavanagh, Ison, of A.P. Offprint only. D.309-D.311 (198) 1994 (With J.M. Woodley) Biotransformation reactor selection (ed. J.M.S. Cabral, D. Best, L. Boross and J. Tramper), pp. 371-394. Chur: Harwood Academic Biocatalysis operation. Applied and In 1992-1994 Offprint only. Contents of reference: copy of published text, correspondence, draft. Lilly's folder divided into three for ease of (199) 1994 (With G.R. Hobbs, N.J. Turner, J.M. Ward and J.M. Woodley) Development of transketolase as a catalyst for carbon-carbon bond formation. Prog. Biotechnol. 9, 463-466 (200) 1994 With M. Suphantharika, A.P. Ison and B.C. Buckland) The influence of dissolved oxygen tension on the synthesis of the antibiotic difficidin by Bacillus subtilis. Biotechnol. Bioeng. 44, 1007-1012 (201) 1994 (With effect chrysogenum. Biotechnol. Techniques, 8, 601-604 H.L. Packer and C.R. Thomas) The speed Penicillium Contents of drafts, referee’s comments and response. folder: photocopy of published text, Offprint only. blending upon Lilly's high of M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 (203) 1995 (With S.J. Warren, E. Keshavarz-Moore, C.R. Thomas and K. Dixon) Rheoiogies and morphoiogies of three Actinomycetes in submerged culture. Biotechnol. Bioeng. 45, 80-85. 1994-1995 Contents of draft. Lilly’s folder: offprint, referees’ comments, D.316-D.317 (204) 1995 (With A.B. Russell and C.R. Thomas) Oxygen transfer measurements during yeast fermentation in a pilot-scale airlift fermenter. Bioprocess Engineering 12, 71-79 Contents of reference: offprint, correspondence, drafts. Lilly's folder divided into two for ease of (205) 1995 (With S.J. Warren, E. Keshavarz-Moore, P. Ayazi Shamlou, C.R. Thomas and K. Dixon) Rheological measurements Actinomycetes in submerged culture. Bioprocess Engineering 13, 45-48 different three of of Use of reasoning the effect of sterilization comparative tools conditions Photocopy of published paper. Contents of Lilly's folder: photocopy of published paper, correspondence. (206) 1995 (With C. T. Marshall, K. Gobwewonyo and B.C. for Buckland) evaluation on fermentations to produce acidic fibroblast growth factor. Biotechnol. Bioeng. 47, 688-695 (207) 1995 (With G.A. Dervakos, J.M. Woodley and J. Washbrook) knowledge-based the design of biotransformation processes. system for Trans. |. Chem. E. 73 C, 133-139 (208) 1995 (With M. Suphantharika and A.P. Ison) The effect of cycling dissolved oxygen tension on the synthesis of the antibiotic difficidin by Bacillus subtilis. Bioprocess Engineering 12, 181-186 Contents referees’ reports, draft. Lilly's correspondence, Use of an_ intelligent of folder: offprint, M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Contents of Lilly's folder: photocopy of published paper, figures. Rawas (209) 1995 (With J.A. Littlechild, N.J. Turner, G.R. Hobbs, A. and preliminary x-ray crystallographic data with Escherichia coli transketolase. Acta Cryst. D, 51, 1074-1076 Crystallisation Watson) H.C. and Offprint only. (210) 1996 (With T. Keshavarz and C. Bucke) Problems in scale-up of immobilised cell cultures. In Immobilised cells: Basics and Applications (ed. R.H.Wijffels, R.M. Buittelaar and C. Bucke), pp. 505-510. Amsterdam: Elsevier Offprint only. Poulsen, P.S.J. offprint, and J. of Lilly's folder: Cheetham large-scale production Contents correspondence including re arrangements for conference on immobilized cells. (211) 1996 (With R.H. Wijffels, R.M. Buitelaar, C. Bucke, P.B. Tramper) Guidelines for the characterization of immobilized cells. In Immobilized Cells: R.H. Wijffels, R.M. Buitelaar, C. Bucke and J. Tramper), p.831- 834. Amsterdam: Elsevier Basics and Applications (ed. (212) 1996 (With G.R. Hobbs, R.K. Mitra, R. Chauhan and J.M. Woodley) Enzyme-catalysed carbon-carbon bond formation: coli transketolase. J. Biotechnol. 45, 173-179 1994-1996 (213) 1996 (With R. Chauhan, C. French, M. Gyamerah, G.R. Hobbs, A. Humphrey, J.A. G. Morris, M. Rupprecht, N.J. Turner, J.M. Ward, A. Willetts and J.M. Woodley) Carbon-carbon bond synthesis: the impact of rDNA technology on the production and use of E. Y. Acad. Sci. 782, 513- 525 Contents of Lilly’s folder: photocopy of published paper, Contents of Lilly’s folder: offprint, drafts. coli trans-ketolase. Annals N. D.326-D.327 Littlechild, R. Mitra, of Escherichia Lilly M.D. NCUACS 150/7/06 Publications, D.1-D.366 correspondence, referees’ comments, drafts. Mitra (214) 1996 (With K.G. Morris. M.E.B. Smith, N.J. Turner, from R.K. and using Escherichia coli: the biocatalyst synthesis. Tetrahedron Asymmetry, 7, 2185-2188 procedure for carbon-carbon practical asymmetric Transketolase J.M. a Woodley) for Offprint only. D.329-D.330 1996 Biotransformations (215) immobilized biocatalysts. In Advances in Molecular and Cell Biology, vol. 15 A (ed. Bengt Danielson), pp. 139-147. London: JAI Press using 1992-1996 Contents of reference: offprint, correspondence, draft. Lilly's folder divided into two for ease of Y. Acad. Offprint only. (216) 1996 (With J .M. Woodley) Selection and design of biotransformation processes. Chem. Eng, 611, 28-30 Contents of Lilly's folder: offprint, draft. (217) 1996 (With J.M. Woodley and R.K. Mitra) Carbon- carbon bond synthesis: reactor design and operation for transketolase catalysed transformations. Ann. N. Sci. 799, 434-445 1995-1996 (218) 1996 (With S.P. Brocklebank, R.K. Mitra and J.M. Woodley) Carbon-carbon bond synthesis: preparation and use of immobilised transketolase. Ann. N. Y. Acad. Sci. 799, 729-736 Contents of Lilly's folder: copy of ? published text, letter re acceptance of paper of this title for a conference poster presentation. (219) 1996 (With J.M. Woodley) A structured approach to design and operation of biotransformation processes. J. Ind. Microbiol. 17, 24-29 D.334-D.335 M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 Contents of reference: photograpn, figures, drafts. Lilly's folder divided into two for ease of draft, offprint, enclosing revised letter (220) 1996 (With D.J. Pollard, P. Ayazi Shamlou and A.P. Ison) Saccharomyces cerevisiae fermentation in pilot airlift bioreactor: comparison of air sparger configurations. Bioprocess Engineering 15, 179-288 a Offprint only. S. 1996 (With (221) Dawson) synthesis Biotechnol. Progr. 12, 758-763 Characterisation of the N-acetyl-A-neuraminic Blayer, of J.M. Woodley and M.J. chemo-enzymatic acid (Neu5Ac). Offprint only. probe, and of biomass. on the productivity determined by morphology concentration. rheology Contents of Lilly’s folder: figures only. Contents of Lilly's folder: offprint, drafts. Ison) The (223) 1996 (With effect of culture erythromycin by Saccharopolyspora erythraea in batch culture. Biotechnol. Lett. 18, 1181-1186 S.M. Heydarian and A.P. conditions (222) 1996 (With M. Sarra and A.P. Ison) The relationship between a capitance-based of Saccharopolyspora erythraea cultures. J. Biotechnol. 51, 157-165 propeller on Saccharomyces Contents of ‘First Lecture given by MDL at Opening of ESBES | introduced by Karel Luyben ‘as the “father” of European Biochemical Engineering’: offprint, draft, figures. (224) 1997 The development of biochemical engineering science in Europe. J. Biotechnol. 59, 11-18 (225) 1997 (With D.J. Shamlou) Influence of Lilly’s folder inscribed by Sheila Lilly Pollard, A.P. a Ison and P. Ayazi M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 cerevisiae Bioprocess Engineering 16, 274-279 fermentations in a_ pilot-scale bioreactor. Contents of Lilly’s folder: offprint, figures. D.342-D.343 (226) 1997 (With R.M. Lynch and J. M Woodley) Process design for the oxidation of fluorobenzene to fluorocatechol by Pseudomonas putida. J. Biotechnol. 58, 167-175 Lilly's Contents of folder divided into two for ease of reference: offprint, correspondence, referee's comments, drafts. Woodley) (227) 1997 (With S.S. Barclay, P. Spargo, A. Pettman and J.M. Villiger mono- oxygenase for synthetic biotransformation. Proc. 1997 I. Chem. E. Research Event, pp. 981-984. Rugby: |. Chem. E Production Baeyer of Offprint R.K. Mitra and J.M. 1998 (With D.345-D.346 Lilly's folder divided into two for ease of Contents of reference: offprint, drafts. (229) 1998 (With D.J. Pollard, A.P. Ison and P.A Shamlou) Reactor heterogeneity with Sacchropolyspora erythraea airlift fermentations. Biotechnol. Progress 58, 453-463 (228) Woodley) Transketolase catalysed carbon-carbon bond formation: biotransformation characterisation for process evaluation and selection. Enzyme Microbiol. Technol. 22, 64-67 1996-1998 (230) processing parameters on the feasibility and operational stability of immobilized Microb. Technol. 23, 335-345. Contents of Lilly’s folder divided into three for ease of reference: offprint, correspondence, referee’s comment, drafts. Freeman) Effect of D.348-D.350 1998 (With A. Offprint only. viable microbial cells. Enzyme M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 M. 1998 (With Woodley) (231) Biocatalytic to reactor design. Proc. 1998 Chem. E. Research Event, pp. 446-514. Rugby: |. Chern. E. J.M. characterisation Baeyer-Villiger leading Hogan and Offprint only. (232) 1999 (With R.K. Mitra and J.M. Woodley) Process transketolase- implications catalysed and Biotransformation 17, 21-36 condensations. of aldehyde Biocatalysis properties on_ Offprint only. 1999 (With S. Brocklebank and J.M. Woodley) (233) Immobilised bond synthesis: biocatalytic stability. J. Mol. Catal. B Enzymatic, 295, 191-200 carbon-carbon transketolase for Offprint only. S. Blayer, breakage Turbulent 1999 (With Offprint only. S.M. Heydarian, A.P. Ison and P.A. filamentous batch culture. Chem. (235) 2000 (With Ayazi-Shamlou) bacteria in mechanically agitated Eng. Sci. 55, 1775-1784 (234) J.M. Woodley and MJ. Dawson) Alkaline biocatalysys for the direct synthesis of N-acetyl-D-neuraminic acid (Neu5Ac) from N-acetyl-D- glucosamine (GIcNAc). Biotech. Bioeng. 66, 131-136 Offprint only. (236) 2000 (With J.M. Liddell) Design of a fed-batch control system for microbial hydroxylation Microb. Technol. 26, 530-536 J.M. Woodley and Offprint only substrates. Enzyme Hack, C.J. of toxic of M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 M. 2003 (With J.M. Woodley) (238) Regiospecific a recombinant yeast producing a P4507Ai-yeast reductase fused enzyme. Enzyme Microb. Technol. 33, 606-611 monohydroxylation naphthalene Shimizu and by Offprint only. D.358-D.361 ‘Unpublished’ c.1985-2003 Contents of folder so inscribed. (with W.K. Lang, A.N.C. Weir, G. Holt and A.T. Bull) The effects of successive mutation on the growth kinetics of Bacillus subtilis NC1B 3610 Overproducing L-Lysine c. 1985, 2003 page, Typescript draft with manuscript note from Lilly to Bull on tile 1985; correspondence, 2003 between Sheila Lilly and Bull as to whether the paper had been published. bibliographical reference, latest P. Mohan and A.P. Ison) of with draft the S. Untitled Influence Two folders. manuscript D.359-D.360 revision, — latest the Morphology of Typescript bibliographical reference, 1995. (with Engineering Environmment on eythraea Typescript drafts with manuscript amendment, marginal emphasis etc, latest bibliographical reference, 1994. ? Unpublished. Typescript draft, etc for paper by P. Mohan, A.P. Ison and Lilly, latest bibliographical reference 1994. ‘An Engineering Review of Bioreaction Scale up’ M.D. Lilly NCUACS 150/7/06 Publications, D.1-D.366 D.362-D.366 PUBLICATIONS CORRESPONDENCE 1969-1998 Biocatalysis Correspondence re reviewing papers, etc. Lilly joining the editorial board, 1991-1992 D.363-D.364 Biotechnology and Bioengineering 1969-1997 Correspondence and papers. 2 folders. Lilly was involved with the journal as author, reviewer and associate editor. Enzyme and Microbial Technology 1991, 1997 review of manuscript and Board Correspondence re meeting. Miscellaneous shorter correspondence Lilly was a member of the editorial board. 1991-1998 M.D. Lilly NCUACS 150/7/06 SECTION E LECTURES, E.1-E.69 1966-1996 ‘Periodic changes in amidase synthesis by Pseudomonas aeroginosa in continuous culture’, Society for General Microbiology, 27 September 1966 1966-1967 Drafts of paper by A.Boddy, P.H. Clarke and Lilly, figures. Also spring term 1967 colloquia list for UCL Faculty of Medical Sciences which lists talk by Lilly on PSeudomonas aeroginosa under the title ‘Oscillations in bacterial enzyme synthesis’. talk, Untitled Conference on Enzyme Engineering, Hampshire, USA, 9-13 August 1971 Engineering Foundation Research New Henniker, Manuscript draft of Lilly’s talk beginning ‘I would like to spend the first few minutes summarising our work on immobilisation at UCL and then talking about some of our recent work’, list of participants, conference information. International ‘Immobilised Fermentation Symposium, Kyoto, Japan, March 1972 Reactors, Enzyme Fourth Typescript draft. Incomplete manuscript drafts. ‘The Bioengineering of Immobilised Enzymes, Rouen, France, 1972 manuscript fragment Untitled immobilised enzymes, lists of slides and ‘definite targets by December 1972’ Untitled manuscript fragment for paper in a session on reactor design, Second Engineering Foundation Research Conference on Enzyme Engineering, [New Hampshire], USA, 5-10 August 1973 Although found separately the manuscript fragment may relate to papers at E.4 Henniker, of talk on M.D. Lilly NCUACS 150/7/06 Lectures, E.1-E.69 Untitled manuscript notes, Foundation for Research Second Japan, May 1974 Research of list Conferences slides for paper at Chemistry, in Osaka, Conference on Catalysis, Also list of participants and conference schedule. ‘Enzyme Technology - End of the Beginning’, Institution of Chemical Engineers Congress on Advances in Enzyme and Membrane Technology, London, 12 May 1977 Manuscript draft of Lilly's paper, conference programme, etc. ‘Immobilzed Enzyme Reactors’, First European Congress on 25-29 September 1978 Biotechnology’, Switzerland, Interlaken, Typescript draft, photographs, correspondence re lecture, programme, etc. Four folders. seminar and their on See also H.14. Incomplete typescript draft. ‘Developments in Biocatalysis’, plenary lecture, Achema Congress, 22 June 1979 ‘Applications of immobilized enzymes / cells - Nordforsks cellsystems processes’, Lund, Sweden, 13-14 May 1980 correspondence re preparation of lecture. Manuscript programme, demonstration and poster abstracts correspondence ‘Two-liquid Society, London, June 1982 a survey’, and and Lilly’s lecture, arrangements, ‘Immobilized in application enzyme- analyses biocatalytic Typescript typescript draft of drafts of lecture published paper, phase reactors’, The Royal and and re M.D. Lilly NCUACS 150/7/06 Lectures, E.1-E.69 Interactions ‘The Recovery’ between Fermentation and Protein unidentified Typescript Undated, latest bibliographical reference 1983. lecture draft for of occasion. ‘Two-liquid Phase Biocatalytic Reactors’, Biotechnology Colloquium, Rutgers University, New Jersey, USA, Spring 1984 Transcript of Lilly's ‘off the cuff paper with covering letter, 18 July 1984 ‘SERC [Science Presentation’, 6 December 1985 and Engineering Research Council] Manuscript notes, transparencies, etc. Typescript notes. of Chemical Industry Manuscript and typescript draft, list of slides, programme. ‘Presentation to Meeting at New Orleans on January 21st 1986’ ‘Industrial Use of Biocatalysts for Asymmetric Synthesis’, Society Fine Chemicals Group Symposium on Asymmetric Synthesis - Prospects for Industry’, London, 20 March 1986 1967-1988 ‘Biochemical Engineering - Its Contribution to Society’, Sixth Sir Harold Hartley Memorial Lecture, Royal Society, London, 20 January 1988 Typescript drafts of Lilly's presentation, programme, list of participants, published proceedings. ‘Biocatalysis’, Research and Development Seminar ‘The Compleat Catalysis’, Unilever House, London, 9 May 1986 E.21-E.22 E.23-E.27 Two folders. M.D. Lilly NCUACS 150/7/06 Lectures, E.1-E.69 to Invitation arrangements and arising, including Lilly's correspondence with Hartley (E.27), etc. re drafts, background material correspondence ' lecture, deliver Five folders. ‘Lecture - Williamsburg’ Contents of folder so inscribed: typescript draft of lecture headed on Undated, latest bibliographical reference, 1988. first page ‘Fermentation’. Two-liquid Phase Biocatalysis: Choice of Phase Ratio’ Typescript draft of Undated, D.268. latest ? lecture for unidentified occasion. See reference, bibliographical 1989. ‘Lecture at Tel Aviv (1991)’ to biological the design and Lilly's keynote lecture ‘Biochemical the Typescript and manuscript lecture notes, faxes, etc at annual IChemE Engineering industries’, Lilly described ‘some of our work on operation of two-liquid phase biocatalytic reactors’. Relates ?to meeting, Research Research: its contribution January 1992. See D.283. Contents of folder so inscribed: manuscript notes on index cards, etc. 1991-1992 immobilized ‘Biotransformations Mosbach Symposium, 2-5 December 1992. ‘Advances in Lecture, January 1993 Transparencies etc for Lilly's lecture. biotransformation processes’, Dankwerts See H.50, H.51. entitled using biocatalysts’, M.D. Lilly NCUACS 150/7/06 E.35-E.38 Lectures, E.1-E.69 Typescript draft, background papers, correspondence, etc. See D.298-D.300. ‘Ascona (27.2.94)’ Spp typescript draft so titled, manuscript list of slides. Lilly talked ‘about biochemical engineering to illustrate the crucial part that it has played in many past and present innovations in medicine’. ‘The development of biochemical engineering science in Europe’, 1st European Symposium on Biochemical 19 Science, September 1996 Plenary lecture, Engineering Ireland, Dublin, Typescript drafts, slides, figures, etc. Four folders. Biochemical Reactors’ Manuscript notes. Manuscript notes. folder illustrative ‘| Chem E lecture Mtg’ - including 96? two ‘Biochemical Engineering’ inscribed material for Contents of Brighton’: photographs. Typescript draft. This lecture was delivered to the Biochemical Society at the University of Bath. ‘The Challenge of the Universities’ Biochemical Reactors’ M.D. Lilly NCUACS 150/7/08 Lectures, E.1-E.69 ‘The Use of Immobilized Enzymes in Reactors’ Typescript draft. E.44-E.58 Unititled lecture notes and drafts the Although these notes and drafts topics are sometimes identified the opening paragraph, for example advances in biotransformation at E.50 and biotechnology at E.51. lack formal titles by Lilly in Fifteen folders. E.59-E.69 Illustrative material for lectures and papers Eleven folders. M.D. Lilly NCUACS 150/7/06 SECTION F SOCIETIES AND ORGANISATIONS, F.1-F.372 1968-1998 ADVISORY BOARD FOR THE RESEARCH COUNCILS (ABRC) AGRICULTURAL AND FOOD RESEARCH COUNCIL (AFRC) BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) F.16-F.28 BIOTECHNOLOGY JOINT ADVISORY BOARD (BJAB) BIOTRANSFORMATION RESEARCH ADVISORY GROUP (BRAG) F.30-F.36 COBIOTECH (ICSU INTERNATIONAL SCIENTIFIC COMMITTEE FOR BIOTECHNOLOGY) F.133-F.160A F.165A F.166-F.271 E637 ENGINEERING FOUNDATION F.38-F.132 EUROPEAN COMMISSION (EC) F.161-F.165 EUROPEAN SCIENCE FOUNDATION (ESF) EUROPEAN FEDERATION OF BIOTECHNOLOGY (EFB) BIOTECHNOLOGY AND BIOENGINEERING (IOBB) INSTITUTE FOR BIOTECHNOLOGY STUDIES (IBS) / INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY (IIB) HOUSE OF LORDS SELECT COMMITTEE ON SCIENCE AND TECHNOLOGY Fa2(S-F 295 INTERNATIONAL ORGANIZATION FOR eae INSTITUTION OF CHEMICAL ENGINEERS M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 LABORATORY OF THE GOVERNMENT CHEMIST (LGC) F.296-F .322 MASSACHUSETTS INSTITUTE OF TECHNOLOGY F.323-F.333 ORGANISATION FOR ECONOMIC CO- OPERATION AND DEVELOPMENT (OECD) F.334-F.341 PUBLIC HEALTH LABORATORY SERVICE (PHLS) F.342-F.344 ROYAL ACADEMY OF ENGINEERING F.345-F.352 ROYAL SOCIETY F.353-F.367 SCIENCE AND ENGINEERING RESEARCH COUNCIL F.368-F.370 UNIVERSITY OF CAMBRIDGE papers re ABRC_ Research a ROM bore WOLFSON FOUNDATION Correspondence Opportunities discussion. and Includes Biochemical Engineering’. note ADVISORY BOARD FOR THE RESEARCH COUNCILS (ABRC) 12 folders and AFRC handbook. AGRICULTURAL AND FOOD RESEARCH COUNCIL (AFRC) Invitation meetings. ‘Real Opportunities in correspondence by Lilly on and papers re 1991-1993 to serve, M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 In December 1991 Lilly was invited to serve as a member of a new Engineering Research Board BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) ‘Bioprocessing in the New Biotechnology and Biological Sciences Research Council’, discussion paper by Peter Dunnill. F.16-F.28 BIOTECHNOLOGY JOINT ADVISORY BOARD (BJAB) 1992-1994 Correspondence workshops, etc. and papers re Board meetings, underpin successful industrial innovation and Thirteen folders. to serve a member of the Lilly accepted an BJAB, 1 September 1992 - 31 August 1994. invitation The BJAB was set up in 1989 by by the Department of Trade and Industry and the Science and Engineering Research Council. They were subsequently joined as full partners or observers by the other Research Councils. The BJAB’s mission was ‘to draw research base and industrial practitioners into the development of a strategy to to encourage the funding bodies to implement it’. Lilly was a member of the Advisory Group. BIOTRANSFORMATION RESEARCH ADVISORY GROUP (BRAG) Agenda for meeting only. M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.30-F.36 COBIOTECH (ICSU INTERNATIONAL SCIENTIFIC COMMITTEE FOR BIOTECHNOLOGY) 1990-1996 Correspondence and activities, relations with IOBB (qv), etc. papers re meetings, COBIOTCH Seven folders Papers at ‘Cobiotech Group 1994, MonteCarlo, Monaco’. F.33, Steering F.34 were found Meeting a in 20-21 file labelled November COBIOTECH was established under the auspices of ICSU with the overall goals of promoting biotechnology for the benefit of mankind, of advancing research and education, and of transferring information and resources in the field of technology. In 1994 Lilly formally accepted nomination to the Steering Group of COBIOTECH. 1993-1997 1990-1998 F.38-F.132 1993, Lilly was receiving After appointed to the Award Committee. the Award himself in ENGINEERING FOUNDATION EUROPEAN COMMISSION (EC) Brief correspondence re Enzyme Engineering Award Committee. Miscellaneous Human Capital and Mobility Programme/European Biochemical Engineering Network (EBEN) Framework IV F.118-F.122 Framework V F.38-F.55 F.56-F.117 FeiZe-F lioZ M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.38-F.55 Human Capital and Mobility Programme / European Biochemical Engineering Network (EBEN) 1991-1997 Engineering Network was The European Biochemical selected for funding in the European Commission Human Capital and Mobility Programme. The Advanced Centre for Biochemical Engineering, University College London was a participant. It was run by Technische Universitet Delft. Lilly's folder divided into Contents of for ease of reference: correspondence and papers re proposal for European network. five Lilly's correspondents include Department of Education and Science and European colleagues. Lilly UCL colleague Peter Dunnill also appears as correspondent. Lilly's folder divided into Contents of four for ease of reference: correspondence and papers re proposal for European network 1992-1993 1991-1992 1993-1997 F.38-F.42 F.43-F.46 F.47-F.54 8 folders. ‘Europe - Socrates - Erasmus’ 1994-1995 Contents of papers. folder so inscribed: correspondence and Includes manuscript and typescript drafts for proposal. Miscellaneous corrrespondence and papers found loose 1991-1998 Correspondence and papers re biochemical engineering science activity in Framework IV engineering The IV biocatalyst- coordinated the Lilly science in biochemical engineering programme encapsulated The first paper in the folder inscribed ‘File - EBEN’ biochemical IV _ Programme. F.56-F.117 Framework IV science Framework the concept of European Framework M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 based factory process under the title ‘Cell Factory’. F.56-F.70 Correspondence and papers re biochemical engineering science proposal 1991-1992 In December 1991 a two-day meeting was held in the UK to discuss the lack of biochemical engineering research in EC Framework Ill BIOTECH programme. The outcome was Engineering Science - Strategic Case for a Clear Focus in Framework lV’ European Commission in January 1992. ‘Biochemical document submitted entitled (F.63), which was the to a October 1991 November 1991 ‘Bio-Process Research Programme Outline Case for Clear Focus in Framework IV’ a F.59-F.63 January 1992 February 1992 Paper prepared by UK DTI [Department of Trade and Industry] Biotechnology Unit Four folders and one bound paper (F.63) ‘Biochemical Engineering Science Strategic Case for a Clear Focus in Framework IV January 1992’ Two folders. March-April 1992 May 1992 0%, 6.68 June 1992 M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 October 1992 Photocopies of 1990 correspondence found with papers relating to Framework IV proposal F.71-F.77 ‘Framework IV November 92’ 1991-1993 Contents of folder so inscribed divided into seven for ease of reference: correspondence and papers re meeting on Biochemical IV, Amsterdam, The Netherlands, 9-10 November 1992 Engineering Framework Science in meeting, The aim of the meeting was to build on the December 1991 the scientific content of a Biochemical Engineering Science programme, the recommendations to be submitted to the EC for further consideration. up recommendations for drawing Correspondence and papers F.78-F.87 Science Proposal a adhe, Engineering January 1993 February 1993 Bound proposal document. ‘Biochemical for Research Programme in Framework IV January 1993’ Includes Lilly's suggested form of words for a biochemical engineering science theme under the Life Sciences and in the revised draft of Framework IV, Technologies line conveyed the Directorate General for Science, Research and Development by the Department of Trade and Industry. March - May 1993 European Commission to M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 June - July 1993 Lilly presented Science in Framework IV’. ‘The Case for BioChemical Engineering October 1993 F.84, F.85 November 1993 Two folders a and ‘copy of the latest Commission text on Life At F.84 is for Sciences inclusion in Framework IV’, sent to Lilly by the Department of Trade and Industry. Technologies, proposed which is re Round Table’ a letter from Lilly, all At F.85 is participants of the Framework IV Biochemical Engineering Group enclosing a note on ‘Area No. 1 Biotechnology 1.1 Cell Factories’ setting out the ‘Objective’, ‘Implementation’ and ‘Research tasks’. 3 November 1993, to and a Dutch papers IRDAC December 1993 16 November Lilly colleague Hans On Tramper visited Brussels to have further discussions on Biochemical Engineering in Framework IV. Includes on ‘Demonstration in Life Sciences’, Brussels, 13 December 1993. 1993-1994 Contents of folder so inscribed divided into two for ease of reference: includes Framework IV proposals, papers for EBEN meetings. ‘Report of the IRDAC Round Table on "Demonstration in Life Sciences" Brussels, 13 Dcember 1993’ ‘UCL - Framework IV’ i tekoh, cokes M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.90-F.96 Correspondence and papers re Field Review Group on Cell Factories, Framework IV etc. Contents of untitled folder divided into seven for ease of reference: first meeting of Group, Brussels, 28 April 1994. includes papers re F.97-F.104 Correspondence Framework IV etc and papers re EBEN_ meetings, Framework Includes Framework IV Biotechnology Event (attended by The Hague, 26-27 November 1994. IV _ proposals and papers re Lilly), Eight folders. These papers were found in considerable disorder. F.105-F.117 Correspondence and papers re Framework IV etc 1995-1998 Thirteen folders. F.118-F.122 1996-1997 aims and objectives of list of For texts the Framework IV He gave the opening lecture. See F.112 for participants and F.113 for text of Lilly's lecture. prepared for publication see F.116. the conference programme and Principally re European Cell Factory Conference, Lund, Sweden, 27-30 April 1997. B. Hahn-Hagerdal at Lilly organised this meeting with The objective of the Lund. conference was to review progress to date in achieving the Cell Factories Programme. Framework of BPA [Biotechnology Action Programme] Correspondence and papers re Framework V preparation. ‘European Laboratories Without Walls [ELWW] in Miscellaneous Framework V the 1990 F.123-F.132 123 Five folders. 1990-1997 M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 and BRIDGE’ foider so respect iabelied: of proposais for Council Contents of decisions development in programmes in agriculture and agro-industry and the life sciences and technologies, carbon of letter from Lilly re discussions on Commission’s work with biotechnology and booklet on the ELWW. research and ‘European Social Fund’ Contents of folder so labelled: project description forms, manuscript notes. eZee dee European Harmonisation’ 1993-1997 Contents of folder so labelled divided into three for ease of reference: European Doctorate of Biotechnology qualifications in biotechnology. correspondence and in harmonisation papers and re folder so 1995-1996 i 1 2OshAdoe ‘EC - Grant Evaluation’ Contents of papers. inscribed: correspondence and ‘FITB [Flexible and Interactive Training in Biotechnology] Europe’ Contents of folder so inscribed divided into two for ease of reference: correspondence and papers re biotechnology evaluation. September 1994 Published report of survey undertaken by Ernst & Young and supported by the SAGB (Senior Advisory Group the Biotechnology) with economic 27 September 1994 and Lilly's manuscript notes on back of attendance list. ‘Biotechnology’s economic impact in Europe: A survey of its future role in competitiveness’ ‘Biotechnology - London, Piste 32 invitation to Two folders. stakes for Europe’ meeting, M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.133-F.160A EUROPEAN (EFB) FEDERATION OF BIOTECHNOLOGY 1977-1997 F.1383-F,136 ‘Formation of the EFB’ 1977-1984 Contents of folder so inscribed divided into four for ease of reference: EFB, Newsletters no.5, September 1982 and no.7, September 1984. 1977-1978 formation papers of re F.137-F.154 EFB Working Party on Immobilized Biocatalysts 1980-1996 Correspondence meetings. and papers including minutes of Lilly was a founding member of the Working Party. The inaugural meeting, chaired by P.B. Poulsen, was held in Copenhagen, 19 May 1980 1980 F.140-F.141 1982 Two folders. F.137-F.138 of delegates and their background in the Includes ‘List field’, August 1980 (F.138). Includes at F.141 ‘the final approved “Guidelines for the Characterization of Immobilized Biocatalysts”.’ F.143-F.144 Two folders. 1984 Two folders. M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.145-F.146 1985 Two folders. F.150-F.151 1go2 Two folders. 1994 Two folders. F.155-F.158 F.154-F.154A 1995-1996 Includes letter from the Managing Editor, Biocatalysis, 23 May 1994, re future developments of the journal. At F.154A are Lilly’s manuscript notes and transparencies for meeting or meetings. National Contents of folder so inscribed divided into four for ease of reference: correspondence and papers re workshop with representatives and delegates from the European Federation of Biotechnology, Brussels, 9 April 1992. ‘European Federation of Biotechnology EFB’ transparencies (F.156) and presentation presentation of the European Commission Includes Brussels for for Lilly at by at M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 Academy of Sciences, Washington DC, 18 August 1992 (108): F.159-F.160 ‘EFB - Biochemical Engineering Science - New Initiative’ 1995-1997 Contents of folder so labelled divided into two for ease of reference: correspondence and papers re EFB Section on Biochemical Engineering Science. Lilly was a member of the Board of the Section which met for the first time on 21 September 1996 ‘Manpower and Training Implications of the Expansion of Biotechnology Based Industries’ a charged workshop The introduction explains that the EFB commissioned in 1979-1980 the problems of education in the member countries and that report the experts present belonging to the eleven following countries: Germany, France, Greece, Ireland, Italy, the Netherlands, Norway, Poland, Switzerland and the United Kingdom. established studying been with has by Five folders. F.161-F.165 EUROPEAN SCIENCE FOUNDATION (ESF) Lilly was a member of the working group which produced the report. Correspondence and papers re ESF Process Integration in Biochemical Engineering Programme. 1992-1996 to submit written evidence to Regulation Sub- UK _ biotechnology HOUSE SCIENCE AND TECHNOLOGY Lilly was invited Committee Il - Lilly Committee. COMMITTEE Programme SELECT LORDS Steering member of the was a OF ON of the M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 industry and its global technology. inciudes questions on which evidence was invited and drafts of Lilly's response. F.166-F.271 INSTITUTE FOR BIOTECHNOLOGY STUDIES (IBS) / INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY (1B) 1980-1996 College London, University The Institute for Biotechnology Studies was a charitable organisation established in 1983 by the Polytechnic of Central the University of Kent at Canterbury. The aims of the Institute developments were in multidisciplinary The management biotechnology research and teaching. group comprised A.T. Holt, Polytechnic of Central London and Lilly, University College London. Bull University of Kent, promote London and G. to The name of the Institute was changed to the International Institute of Biotechnology in 1989 ‘Consortium’ F.166-F.174 See also B.17. Principally manuscript notes and drafts found at the front of the binder, 1981-1982, most undated Contents of ring binder so labelled: correspondence and papers re formation of a biotechnology consortium in the South East of England. 1980-1983 Includes copy of letter from the Prime Minister, Margaret Thatcher, to Lord Ironside, 20 January 1981. Includes ‘A Proposal for the Formation of a Biotechnology Consortium in S.E. England’, 2pp typescript. November 1980 - January 1981 June - November 1981 M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 January - May 1982 June 1982 July 1982 Includes Trust deed for The Biotechnology Institute and Studies Centre. August-September 1982 October 1982 - January 1983 N.d. ‘Institute for Biotechnological Studies Trustees Meetings’ Includes Association of the Ltd. photocopy of Memorandum and of Institute for Biotechnological Studies Articles ‘Institute for Biotechnological Studies Trust Management Committee’ Contents of folder so labelled: agenda and minutes of meetings. 1982-1983 to announce joint The programme with a number of and companies on developing the use of biocatalysts. Contents of folder so labelled divided into two for ease of reference: agenda and minutes. Contents of folder so inscribed: includes drafts, editors and others to whom press release sent, etc. ‘DTI [Department of Trade Press Release’ press release was DTI the Fal/6-F We and Industry] Programme list of research industrial M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 ‘PCL [Polytechnic of Central London] Correspondence’ Conients of foider so inscribed: inciudes carbon of Lilly's letter, 4 August 1983, re Inner London Education Authority Review of Advanced Further Education in Inner London. ‘Efficiency Case Study |.B.S’ 1984-1986 Contents papers re case study on the IBS. folder labelled: so of correspondence and The case study was undertaken ‘to practical evidence of how the University’s organisational structure aids or hinders the development of an academic initiative’. provide ‘1.B.S. Patenting’ of folder Contents and papers re seeking patent protection ‘for use of benomy!| to obtain unexpectedly improved production of penicillin’. correspondence labelled: so 1985-1988 1982-1989 F.182-F.184 F.185-F.215 Contents of two box files ‘|.B.S. - Biennial Conference’ ‘Extended use of Biocatalysts Research Grant’ Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re organisation of the first IBS Biennial Conference. 1982-1989, n.d. This was a joint programme with the Department of Trade and Industry and Industrial Companies: Shell Research Ltd, Unilever Research, May and Baker Ltd, Glaxo Group Research Ltd, Grand Metropolitan Biotechnology, Perkin Elmer and Imperial Chemical Industries. The project, of five years duration, was started in September 1983. The programme set out to begin to answer the question as to why microorganisms only synthesise useful products for a an understanding of the reasons for this their useful lives as catalysts can be extended. General correspondence and papers whether from F.185-F.193 to ascertain limited time and M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 October 1982 - March 1983 April 1983 - September 1983 October 1983 - March 1984 April - June 1984 July - September 1984 October, December 1994 January - October 1985 1988-1989 3 April 1985 F.194-F.195 1983-1987 ‘Institute Department of Trade and Industry Companies Grand Met’ Contents of folder so inscribed divided into two for ease of reference: on behalf Metropolitan of Biotechnology Ltd. 1985-1988 Papers for each meeting were found in separate folders. principally correspondence between Lilly Correspondence Meetings and papers re_ Industrial Liaison Includes transparencies. F.196-F.202 the Institute and Grand M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 11 April 1986 3 October 1986 27 March 1987 2 October 1987 25 March 1988 25 October 1988 F203-F 215 for an_ industrially-supported research Proposal and reports Report for Industrial Proposal programme Bound copies of documents. With manuscript annotations. Loose copy enclosed, also with manuscript annotations. ‘Progress Liaison University College London on Thursday 1983’ N.d., 1983-1989 With marginal emphasis. Annotated on front cover ‘Team Leader's copy’. ‘Progress Liaison University of Kent on Thursday 5 April 1984’ Industrial Report Annotated on front cover ‘Team Leaders copy’ Meeting at December 1 for Meeting at M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 Report ‘Progress Polytechnic September 1984’ of for Central Industrial London Liaison Meeting on Wednesday at 26 Annotated on front cover ‘Team Leaders copy’. ‘Progress Report for Industrial Liaison Meeting at Perkin Elmer Limited on Wednesday 3 April 1995’ ‘Progress Report for Industrial Liaison Meeting at Glaxo Group Research Limited on Friday 4 October 1985’ Progress University College London on Friday 11 April 1986’ Industrial Liaison Report for Meeting Progress University College London on Friday 3 October 1986’ Industrial Liaison Report Meeting for at at ICI at Report for for Report Liaison Liaison Meeting Industrial Industrial Liaison Meeting at ‘Progress Report for (London) on Friday 2 October 1987’ ‘Progress University College London on Friday 25 March 1988’ Industrial Progress at University of Kent at Canterbury on Friday 27 March 1987’ January 1989 Progress Report for Industrial Liaison Meeting at Rhone Poulenc Ltd on Tuesday 25 October 1988’ Final Report of the Institute’s 5 year research programme - 1 September 1983 - 31 August 1988 Meeting M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 General correspondence and papers 1986-1996 etin Executive Committee and eed OMe? 17 1986-1987 Two folders. F.219-F.223 1989 Five folders. F.224-F.227 1990 Four folders. Five folders 1992 Five folders. F.238-F.241 1993 F.228-F.232 1991 F.233-F.237 Four folders. F.242-F.249 F.250-F.253 1995 Four folders. 1994 Eight folders. M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.256-F.269 Miscellaneous papers and reports 1983-1994 FezZ66 Memorandum and Articles of Association 1983 Printed papers: ‘Survey of Activities’, July 1985, ‘Research Opportunities in Biotechnology’, ‘Continuing Education in Biotechnology’, in Biotechnology’, etc ‘Information Advisory Service & In original folder. ‘1987 Policy Review' Annual General Meeting, 27 September 1990 Bound copy of agenda and papers for meeting. Inscribed on title page ‘The Gospel according to David [J. Hardman]!’ Two papers on the President's Plan for the Future and Institute Development ‘Companies Limited by Shares’ ‘1990 Policy Review’ Annual General Meeting, 12 March 1991 Bound copy of agenda and papers. M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 prepared Paper Executive Secretary, David J. Hardman as directed at the meeting of ihe Board on 12 March 1991, 30 July 1997. Directors the the for by Annual General Meeting, 12 March 1992 Bound copy of agenda and papers. Annual General Meeting, 10 March 1993 Bound copy of agenda and papers for meeting Annual General Meeting, 6 June 1994 Bound copy of agenda and papers. ‘Principles of Gene Cloning and Analysis’ by the Institute between and produced by the produced A manual of Biotechnology for the COMETT programme (programme on universities regarding training in the field of technology), author T.A. Brown, UMIST Manchester. International cooperation enterprises ‘Expression of recombinant genes’ Enclosed compliments slip is inscribed ‘For circulation to Executive Directors, 26/5/94’. 1991-1992 A manual of Biotechnology for the COMETT programme (programme on and _ universities regarding training in the field of technology), author M.F. Tuite, University of Kent at Canterbury. ‘Biodiversity Ltd Overlaps with IIB’. Contents of folder so ‘International Objectives’ Statement of Biotechnology Biodiversity Ltd ri2/O-e 210 International cooperation enterprises Institute of Institute between M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 inscribed correspondence and papers. divided into two for ease of reference: INSTITUTION OF CHEMICAL ENGINEERS 1991-1994 Miscellaneous correspondence and papers. See also A.8-A.10. F.273-F.295 INTERNATIONAL ORGANIZATION FOR BIO- TECHNOLOGY AND BIOENGINEERING (IOBB) 1968-1997 Correspondence and papers. 1968-1969 In a notice in Biotechnology and Bioengineering, 1975 (see F.276) Lilly as chairman explained that the |OBB was a non-profit organisation created in 1968 by Professors C.-G. Heden, |. Malek, G. Terui, H.G. Gyllenberg and E.L. Gaden Jr, and that it had been responsible for various training courses in biotechnology and bioengineering and sponsorship of many international symposia. UCL biochemical engineering was a member from the late 1960s and Lilly served the lIOBB in a number of capacities including a period as chairman. He was elected to the honorary membership of the lOBB in 1996, one of the first two honorary members of the organisation. Cairo, 13 November-12 December 1972. Objectives, statutes etc. Programme etc basic research in fermentation technology, Institute of Nutrition, training course on for regional N.d. 1972 Lilly M.D. NCUACS 150/7/06 Societies and organisations, F.1-F.372 The IOBB was one of the sponsoring bodies. 1975 Includes Statutes, January 1975 and notice on the IOBB written by Lilly, the current chairman, for Biotechnology and Bioengineering 17(2) 1975. 1976-1979 Newsletters, Includes correspondence, re dues to Pure and Applied Biophysics, 1979. 1976 and and the International Union of 1977 Includes minutes of meeting, 1980 and Newsletters, 1982 1983 1984 1985 Newsletters. Includes Newsletters. Includes Newsletters and Statutes. List of laboratories registered 1989. Includes minutes of AGM, July 1988, circulated January 1989. ‘l.0.B.B. Directory 1989’ 1989 M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.284-F.285 1990 Two folders. Principally membership applications. 1991 Includes Newsletters and membership application. 1992 Includes minutes of IOBB General Assembly, 18 August 1982. F.288-F.289 1993 Two folders. Four folders. 1995 1996-1997 F.290-F.293 1994 international organisations such relations with and ICSU as Correspondence and papers re new IOBB Statutes, |OBB Chairmanship, etc. Includes correspondence and papers re other COBIOTECH. Newsletter, October 1996. Includes correspondence and papers re COBIOTECH. Includes membership honorary IOBB and Lilly's September notification of relations with election to 1996 of IOBB, M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 LABORATORY OF (LGC) THE GOVERNMENT CHEMIST 1986-1990 Correspondence and papers re The Biotransformation Club. Biotransformation the The Biotechnology Research Group of the Laboratory of the Government Chemist. research establishment of the Department of Trade and Industry. operated Club LGC was was The by a The rationale of the Club was that biotransformations would effect many sectors of industry and that there was a clear need for these sectors to be aware of the many opportunities that biotransformations could offer. Lilly was a member of the Club on behalf of the UCL Department of Chemical and Biochemical Engineering. F.296-F.322 MASSACHUSETTS INSTITUTE OF TECHNOLOGY 1971-1982 of material for photocopies Fermentation See also H.27. Lilly was a contributor. Principally Technology courses. ‘O2 Transfer in Biological Systems ... by A.E. Humphrey’. Fermentation Technology Course, Massachusetts Institute of Technology, Cambridge, Massachusetts, 23-27 August 1971 The folder also includes title page only for ‘Tables and Graphs on Topic No. 5 “Mass Transfer’ ... by Daniel C. Wang’. Fermentation Technology Course Massachusetts Institute of Technology, Cambridge Massachusetts, 24-28 July 1972 ‘Topic No. 6 Translation to Different Operating Scales ... By: A.E. Humphrey’ F.297-F.297A M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 ‘Notes, Tables and Graphs on Topic No.11 “Enzyme Isolation” ... by Malcolm Lilly’ Xerox was undated but found with the papers at F.297. F.298-F.300 Fermentation Technology Course Massachusetts Institute of Technology, Cambridge Massachusetts, 30 July - 3 August 1973 ‘Tables and Graphs Topic No. Daniel I.C. Wang’ 5 Mass Transfer ... By: ‘Tables and Figures 8 Control ... By: Arthur E. Humphrey’ Topic No. Instrumentation and ‘Tables and Graphs Topic No. Technology ... by M.D. Lilly’ 11 Enzyme Science and F.301-F.307 F.308-F .322 F.308-F.317 Lecturers Dunnill. include Lilly and his UCL colleague Peter Fermentation Office Massachusetts Institute of Technology Special European Program, London, 23-27 January 1978 Technology Industrial Liaison Contents of binder labelled ‘M.D. Lilly University College London’ divided into seven for ease of reference: list of lecturers, course outlines, daily lecture schedule, lecture materials (tables and figures) and reference materials. 1981-1982 Contents of ring binder so titled divided into ten for ease of reference: includes lecturers, course outlines, tables and figures for course topics and reference materials. ‘Massachusetts Institute of Technology Industrial Liaison Program European Course Fermentation Technology’ Fermentation Technology courses, Paris, 15-19 February and MIT, 2-6 August 1982 Lecturers include Lilly. M.D. Lilly NCUACS 150/7/06 F.318-F.322 Societies and organisations, F.1-F.372 correspondence for ease of Contents of untitled folder divided into reference: for Fermentation Technology course in Paris, February 1982 and summer course at MIT, August 1982, photocopy, manuscript material, etc for course or courses. arrangements five re _ 1981-1982 See also H.27. F.323-F.333 ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT (OECD) 1981-1985 Correspondence and papers. In 1981 the OECD commissioned a report on International Trends and Perspectives in Biotechnology from Lilly, A.T. Bull and G. Holt. A draft report was prepared by the end of the year and discussed at a meeting of experts, Paris, 17-18 March 1982. The draft was then modified and completed for submission to OECD member governments and subsequently published. January 1981 June-August 1981 October-November 1981 Includes Note by OECD Secretariat ‘Summary of meeting on in Biotechnology” by A.T. Bull, G. Holt and M.D. Lilly, 17th- 18th March, 1982’. Typescript copy of the draft report. January-March 1982 December 1981 “International Trends and _ Perspectives F.326-F.327 Two folders. M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.329-F.330 April 1982 A duplicated typescript copy of the report submitted to the OECD member governments is at F.329. Two folders. May-December 1982 Includes correspondence and papers re meeting of the OECD Committee for Scientific and Technological Policy which considered the report, 28 May 1982. 1983-1985 Correspondence into languages other than English, reviews of the published report, etc. translations report the of re N.d. aS and the Public Health F.334-F.341 a member of Includes manuscript notes and drafts. PUBLIC HEALTH LABORATORY SERVICE (PHLS) 1988-1998 In July 1988 Lilly was invited on behalf of the Secretary of State for the Department of Health and Social Security to serve Laboratory Service Board. In 1993 the PHLS Board established a Research and Scientific Strategy Committee (RSSC) to be broad responsible for developing its R&D policy strategy the assessment of R&D at the project level. Lilly was invited to join this new Committee and serve as a member of a small Strategic Review Group under an independent Chairman. Lilly's initial appointment to the Board was for three years This was renewed for a further three from 1 August 1998. years to 31 July 1994. After that date he continued as a member of the RSSC until 1998 when he resigned for health reasons. mechanism for setting up a and for M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.334-F.335 Correspondence and papers re invitations to serve on Board, RRSC, Strategic Review Group, thanks for service, letter of resignation, etc. 1988-1998 Two folders. F.336-F.341 PHLS (RSSC) Research and Scientific Strategy Committee 1995-1997 Committee papers. Some with manuscript annotation by Lilly. RSSC meeting, 27 September 1995 Bound copy of agenda and committee papers. RSSC meeting, 16 February 1996 Agenda and committee papers. RSSC meeting, 18 April 1996 Agenda, paper and minutes. F.340-F.341 RSSC meeting, 11 April 1997 ‘RSSC 96/17 Preliminary Analysis of PHLS R&D Activity’ 1991-1998 Correspondence and public awareness of science and engineering, industrial secondment scheme ROYAL ACADEMY OF ENGINEERING F.342-F.343 papers re Agenda and committee papers. Two folders. F.342-F.344 1991-1998 M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 and membership policy Two foiders. Royal Academy of Engineering Evidence to the House of Lords Select Committee on Science and Technology: Sub-Committee I] on Regulation of the UK biotechnology industry and global competitiveness and Lilly contributors to the evidence. UCL his colleague Peter Dunnill were F.345-F.352 ROYAL SOCIETY 1980-1982 F.345-F.348 ‘Roy. Soc. Report 1981’ the F.349-F.351 Contents of folder so inscribed divided into four for ease of reference: correspondence and papers re preparation of report Royal Biotechnology Working Society Group. on Biotechnology and Education by Committee Education ‘Roy Soc / House of Commons 1981/82’ Lilly was a member of the Working Group. Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re Royal Society and House of Commons Education, Science and Arts Committee inquiry into biotechnology. 1980-1982 Lilly was a member of the Royal Society group giving oral evidence to the Select Committee. The brief for the group ‘A is titled Summary of Higher Education for Biotechnology in the United Kingdom’, January 1982. Miscellaneous correspondence and papers is typescript by at F.350. At F.351 Lilly M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.353-F.367 SCIENCE AND ENGINEERING RESEARCH COUNCIL 1984-1996 F.353, F.354 Papers re meetings of Biotechnology Directorate Microbial Physiology Group 1984, 1986 2 folders. F.355-F.359 ‘SERC’ 1987-1993 Contents of folder so labelled divided into five for ease of reference: correspondence and papers re Biotechnology Directorate, Engineering Research Board, establishment of new Biotechnology and Biological Sciences Research Council, etc. Lillyss comments on For biotechnology see F.357. the SERC programme in F.360-F.361 ‘SERC Engineering Board Strategy Advisory Panel’ 1992-1994 a F.362-F.367 correspondence and papers re_ Five folders and bound volume Biochemical Engineering Link Programme Correspondence and papers re management committee meetings, assessment of programme etc. Contents of folder so inscribed divided into two for ease of reference: Lilly's membership of the Strategy Advisory Group, meetings, etc. 1988-1996 For papers re UCL participation in the programme see C.236-C.304, C.930-C.941. Lilly was both grant holder and programme’s management committee. The programme aimed at encouraging firms to work jointly with polytechnics pre-competitive research relevant to industrial needs. universities and on a member of the M.D. Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 F.368-F.370 UNIVERSITY OF CAMBRIDGE 1990-1996 Correspondence and papers re Review Committee for the Institute of Biotechnology and Appointments Committee for the Director of Biotechnology. Two folders and bound volume. Lilly was a member of the Review Committee. F.371-F.372 WOLFSON FOUNDATION Correspondence Renovation, Modernisation & Equipment Programme. Wolfson and papers re Laboratory Two folders. M.D. Lilly NCUACS 150/7/06 SECTION G CONSULTANCIES, G.1-G.157 1968-1997 On occasions Lilly consulted in partnership with his UCL colleague Peter Dunnill as Biotech Consultants. For the beginning of the partnership see G.141. Git ALLIED BREWERIES (UK) LTD G.2-G.4 APCEL LTD G.5-G.18 BECKMAN INSTRUMENTS INC. G.19-G.33 BEECHAM GROUP LTD/SMITHKLINE BEECHAM G.34-G.37 BRITISH GAS PLC G.38-G.42 CELLTECH LTD G.60 G.85 MAY & BAKER LTD G.83-G.84 HUMPHREYS & GLASGOW LTD G.43-G.59 ELI LILLY AND COMPANY G.61-G.82 HERCULES LTD GLAXO GROUP RESEARCH LTD R.T.Z. CHEMICAL LTD MERCK SHARP & DOHME RESEARCH LABORATORIES G.86-G.127 NOVO !NDUSTRI A/S PFIZER INC. RHONE-POULENC M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 G.131 TATE & LYLE INDUSTRIES LTD G.132-G.139 UNILEVER LTD G.140 UOP INC. G.141-G.156 WHATMAN BIOCHEMICALS LTD G.157 W.R. GRACE LTD ALLIED BREWERIES (UK) LTD and papers re_ tryptophan Correspondence and papers re advice on commercial opportunities in biotechnology. 1985-1987 Three folders. APCEL LTD Correspondence project including consultancy agreements, notes of meetings and company brochures. patent, etc. ‘Beckman Consulting’ and ‘Beckman Microbics’ BECKMAN INSTRUMENTS INC. 1974-1980 1974-1979 Contents of folder so inscribed divided into two for ease of including reference: consultancy USA, correspondence agreement, arrangements papers __ visit and_ to M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 ‘Beckman (USA)’ 1975-1980 Contents of folder so inscribed divided into two for ease of papers _ including reference: consultancy agreements, arrangements for and papers arising, etc. correspondence visits and_ Enzymic Conversion of Steroids PD & MDL - Provisional Specification Patent Feb. 1975’ 1974-1978 Contents of folder so labelled with manuscript inscription ‘(See also Beckman correspondence file)’ divided into ten for ease of reference: correspondence and papers re patent including specifications. Correspondents include National Research Development Fitzpatricks Chartered Patent Agents and Corporation, Beckman Instruments Inc. Fitzpatricks acted for Beckman Instruments in the UK. 1969-1992 1969-1980 G.19-G.33 G.19-G.24 papers re advisory 1972-1992 ‘Beecham’ and ‘Penicillin Acylase (Case Project)’ BEECHAM GROUP LTD/SMITHKLINE BEECHAM General and agreements, patent questions etc correspondence Contents of folder so inscribed divided into six for ease of reference: correspondence and papers including notes of meetings. 1982-1994 The papers were found in considerable disorder and the presentation of the significant amount of undated material is tentative. Correspondence and papers including reports on visits, note on biotechnology and British Gas, etc. BRITISH GAS PLC G.25-G.33 G.34-G.37 Nine folders. M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 Four folders. Lilly was invited to join the Research Committee in 1982, serving until 1994. G.38-G.42 CELLTECH LTD 1987-1990 Correspondence agreements, notes of meetings, technical drawings. including papers and consultancy Five folders. G.43-G.59 ELI LILLY AND COMPANY 1987-1997 G.43-G.49 1987-1997 G.50-G.54 ‘Eli Lilly’ Seven folders. Lilly visited research centres in the UK and USA. In 1992 Lilly agreed to serve as a consultant in the areas of fermentation development, biocatalysis and purification for biosynthetic processes. General correspondence and papers including consulting agreement, itineraries, notes and background papers for visits. 1993-1995 Contents of folder so inscribed divided into five for ease of reference: background papers for meetings. Contents of untitled folder divided into reference: background papers for meetings. correspondence, 1990-1993 manuscript five for ease of notes and G.55-G.59 Lilly M.D. NCUACS 150/7/06 Consultancies, G.1-G.157 GLAXO GROUP RESEARCH LTD 1981-1982 Correspondence, discussion etc. consultancy agreement, notes of G.61-G.82 HERCULES LTD 1988-1991 Contents of two box folders labelled ‘Hercules’. to relate papers research The agreement between Hercules Ltd and the Institute for Biotechnological Studies / International Institute of Biotechnology Ltd, University of Kent at Canterbury, in the area of the biodegradation of chemicals. Lilly was a member of the management group. 1988-1991 1989-1991 Six folders. ‘Hercules’ ‘Hercules’ G.61-G.66 of folder so inscribed: G.68-G.70 includes Hercules These papers were found loose in the box. Contents proposal revised June 1989 General correspondence and papers including research agreement, reports on meetings, ‘monthly highlights’, etc. Phase II! Consultancy’ Contents of folder so inscribed divided into three for ease of reference: background papers, manuscript notes etc. Contents of folder so inscribed: includes letter re ‘Hercules ‘University of Kent (Hercules)’ M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 G.72-G.82 Biogradation of Chemicals Progress Reports 1989-1991 G.72 ‘1.2.89 - 30.4.89’ 1.9.89 - 31.7.89' ‘1st August 1989 - 31st October 1989’ ‘Ist November 1989 to 31st January 1990’ ‘1st February - 30th April 1990’ ‘4st May 1990 to 31st July 1990’ ‘Ist January to 31st March 1991’ ‘{st April to 30th June 1991’ ‘Ist October to 31st December 1991’ ‘Ist July to 30th September 1991’ ‘Ist August 1990 to 31st October 1990’ 1978-1980 Correspondence agreement, notes of meetings, etc. HUMPHREYS & GLASGOW LTD and papers including consultancy G.83-G.84 M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 Two folders Lilly worked together with his UCL colleague Peter Dunnill as Biotech Consultants. MAY & BAKER LTD One letter only re visit. G.86-G.127 MERCK SHARP & DOHME RESEARCH LABORATORIES 1985-1994 Although the papers principally relate to consultancy there is little material at G.127 re proposal for support for biochemical engineering at UCL. a G.86-G.101 1985-1991 ‘Merck’ Sixteen folders. G.102-G.104 papers _ including General consultancy agreements, reports on visits, etc. correspondence and_ Contents of folder so inscribed divided into three for ease of reference: includes paper sent to Lilly for information. The assignment of undated material within the sequence is tentative. Contents of folder so inscribed divided into four for ease of Contents of folder so inscribed divided into four for ease of reference: information, background papers for meetings. includes papers sent for G.105-G.108 ‘Merck’ 1986-1988 G.109-G.112 ‘Merck’ 1987, 1990 1987-1990 M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 of reference: includes papers sent for information, draft paper by Lilly and colleagues at Merck. ‘Dr Lilly’ Contents of a US format folder: ?papers made available to Lilly during visit to Merck. G.114-G.126 ‘Merck Patent Problem Litigation’ 1987-1989 Contents of box folder so inscribed divided into thirteen for ease of reference. These papers were found in considerable disorder and the presentation of undated material is tentative. Lilly's correspondence is with Simmons. the lawyers Simmons & 1990-1994 Papers re patent case. for development in NOVO INDUSTRI A/S Correspondence and papers re proposal for support from Merck biochemical academic engineering at UCL, etc 1988-1989 Correspondence and papers re patent litigation. PFIZER INC. One letter only. RHONE-POULENC M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 R.T.Z. CHEMICAL LTD 1981-1982 Correspondence and papers re advice in respect of the research and development capability of John & E. Sturge Ltd in the field of enzyme technology. TATE & LYLE INDUSTRIES LTD Patent application and confidentiality undertaking. G.132-G.139 UNILEVER LTD 1978-1989 Correspondence agreements, notes of meetings, etc. papers and including consultancy Peter Dunnill a Eight folders. also acted as Lilly’s UCL colleague consultant. Correspondence and papers at G.139 relate to patent litigation. Consultancy and Start Up with Roberts, McLennan’ Principally between UOP Process Division and Biotech Consultants (Lilly and his UCL colleague Peter Dunnill). ‘MDL & PD Biotech Consultants’ and ‘Basically Whatmans WHATMAN BIOCHEMICALS LTD G.141-G.144 G.141-G.156 re consultancy agreement UOP INC. 1968-1975 1968-1975 M.D. Lilly NCUACS 150/7/06 Consultancies, G.1-G.157 Contents of folder so inscribed divided into four for ease of reference: correspondence and papers inciuding setting up of Biotech consultants, consultancy agreements, etc. Correspondents include chartered accountants Roberts, McLennan & Co. G.145-G.153 ‘Whatman Board’ 1968-1971 Contents of folder so inscribed divided into nine for ease of including minutes of meetings, reports and financial papers. correspondence reference: papers _ and Lilly was a member of the board of the new company. He submitted his resignation in May 1977. G.154-G.156 ‘Whatman Biochemicals - Technical Consult’ 1969-1970 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers. Lilly on 1981-1982 W.R. GRACE LTD Correspondence and papers including report by Much of the correspondence is between Whatman and P. Dunnill. visit: ‘Some thoughts on biotechnology activities’. M.D. Lilly NCUACS 150/7/06 SECTION H VISITS AND CONFERENCES, H.1-H.76 1964-1998 Society Fermentation Symposium, London, 13-17 April 1964 Chemical Industry 2nd __ International of Abstracts of papers and list of participants. Chemical Macromolecules, Liverpool, 21 November 1973 Symposium Society on _ Catalysis by Two versions of programme with different titles for Lilly’s paper. The titles in the programmes are ‘Industrial Scale Isolation Industrial Catalysts’. The former is crossed out and replaced in pencil with ‘Enzymes in industrial reactors. ‘Enzymes Enzymes’ and as_ of for Foundation Second Japan, May 1974 Research Chemistry Osaka, Research Conferences in Conference on Catalysis, Schedule, abstracts and list of participants. Centenary Lilly spoke on Catalysts’. ‘The Use of Immobilized Enzymes as Weizmann Fermentations December 1974 GIM 74 Genetics of Industrial Microorganisms Second International Symposium, Sheffield, 25-31 August 1974 Second circular and registration form, lists of authors with the titles of their papers. of International Symposium on Immobilized Enzyme Systems, Compiegne, France, 5-7 May 1975 Programme and list of participants. Programme and list of participants ‘Large Manchester, Scale 4 Solvents’, Analysis Meeting Organic for and Control M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 Third International Conference on Enzyme Engineering, Reed College, Portland, Oregon, 3-8 August 1975 Programme Table UCLAF Molecules, Paris, 4-5 March 1976 Roussel Ronde on Polymer Bound Lilly gave a paper on ‘The use of immobilized enzymes in reactors’ of List Roussel UCLAF participants; information about Tables Rondes Bound volume comprising programme and abstracts. H.10-H.11 Conference on the Biotechnical Applications of Proteins and Enzymes on the occasion of the sixtieth birthday of President Ephraim Katzir, Kibbutz Kiryat Anavim, Israel, 23-28 May 1976 lists of Lilly's ‘A Comparison of Cells and Two folders. participants, gave a Lily Enzymes as Industrial Catalysts’. paper on Lilly’s manuscript notes on proceedings. Abstracts, manuscript notes on proceedings. programme, Society of Chemical Industry meeting on ‘Process control and instrumentation in Fermentation’, 13 January 1977 1977-1978 Biochemical GDR Symposium on ‘Isolation and Application of Enzymes in Food Technology and Analytics, Karl-Marx-Stadt, German Democratic Republic, 3-5 November 1977 Invitation to symposium and first announcement only of 12th Meeting, Democratic Republic, 2-8 July 1978. Dresden, German FEBS and Chemical Societies of the Lilly M.D. NCUACS 150/7/06 Visits and conferences, H.1-H.76 International Union for Pure and Applied Biophysics Sixth International 3-9 September 1978 Biophysics Congress, Japan, Kyoto, Third Circular only. First European Congress on Biotechnology, Interlaken, Switzerland, 25-30 September 1978 1977-1978 Press release, announcement and call for papers, list of participants. Training Advanced and Microbiological Technology, University of Lagos, Nigeria, 19-30 October 1978 Biochemical Course on _ Bound volume of programme and papers. was his UCL that An acknowledgement explains was originally planned for January 1978 and was the result of discussions between Lilly, as President of the |OBB and the Division of Basic Science of UNESCO. When the course had to be postponed to October Lilly was obliged to resign as international organiser and teacher. course the by Lilly and Sixth organised Institution Engineers of Chemical For IOBB see F.273-F.295. meeting This colleague Peter Dunnill. The Annual Meeting on Particle Growth Processes, University College London, 4-6 April 1979 International CNRS Symposium on Immobilized Enzymes, Organelles and Cells: Biochemical and Physico-Chemical Aspects’, 23-26 July 1979, Compiegne, France Lilly was a member of chaired a session on enzyme systems. the organizing committee and kinetic properties of immobilized Programme and abstracts. M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 Visit to the Federal Republic of Germany of a group of British research scientists including Lilly, 19-28 September ADN70 1g1g Programmes of visit in English and Germany, letter from Joint Working Party on Biotechnology, 7 secretary of September 1979, thanking Lilly for meeting the working party and agreeing to report to it on his German visit. 13th International TNO Conference on ‘Biotechnology - Hidden Netherlands, 27-28 March 1980 Rotterdam, Shining Future’, Past, a The a Programme booklet. Conference on Immobilzed enzymes and cells and their application in analyses and processes, Lund, Sweden, 13- 14 May 1980 Lilly’s manuscript notes on proceedings. H.23-H.25 re list of Congress’ of Recovery Process Technology’, Biotechnology, Programme booklet. Second Eastbourne, 5-10 April 1981 European Lilly was a member of the Scientific Committee and gave a paper on ‘Multi-Phase Enzymic Catalysis’. First Engineering Foundation Congress on ‘Advances in Fermentation Banff, Alberta, Canada, 7-12 June 1981 1980-1981 Third International Conference on Computer Applications in Fermentation Technology’, Manchester, 31 August - 3 September 1981 Lilly co-chaired a session on ‘Recovery of Intracellular Products’. Correspondence programme, abstracts, manuscripts notes on proceedings. general lecturers, _Lilly’s information and arrangements, Three folders. M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 Abstracts with manuscript notes by Lilly. Course Summer Massachusetts Massachusetts, USA, 2-6 August 1982 Institute on _- of Fermentation Technology, Technology, Cambridge, Correspondence and papers re arrangements. See also F.308-F.322. ‘Immobilised Cells in Biotechnology’, the Polytechnic of Central London, 27-28 January 1983 Bound volume comprising programme and papers. Lilly spoke on Reactor design and operation. House, St the the form of a London, poster advertising Programme in colloquium. Information, Lilly's manuscript notes of proceedings. Lilly spoke on ‘Two-liquid phase biocatalytic reactors’. Prime Ministers Seminar on Science, Technology and Industry, 12 September 1983 Lancaster James’s, Colloquium on Biotechnology: Current Aspects, Rutgers University, New Jersey, USA, 3 April 1984 Programme, list of participants, Lilly's manuscript notes of ‘Current Trends in of Microbial Enzymes’, Novo Industri A/S, Bagsvaerd, Denmark, 10 and 11 May 1984 Anglo-Japanese Workshop in Biotechnology, The Royal Society, London, 2 and 3 May 1984 Programme, abstracts with proceedings on verso. Lilly's manuscript notes of Production and Use M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 proceedings. Lilly gave a Reactors’. paper on ‘Two-iiquid Pnase Biocatalytic H.33, H.34 Third European Congress on West Germany, 20 August-4 September 1984 Biotechnology, Munich, List and supplementary list of participants. Two folders. ‘Development of Second Generation Bioreactors for the Agro-Food Industries’, Braunschweig, West Germany, 7-9 November 1984 Bound volume comprising programme, papers etc. meeting The the Commission of the European Communities Biomolecular Engineering Programme. auspices under held was the of Lilly was co-chairman of a Seminar on Scale-up. Programme, Lilly's manuscript notes of proceedings. ‘Biocatalysis in Research and Society Symposium, London, 19 June 1986 Organic Synthesis - Opportunities for Industry’, of Chemical Industry ‘Biotechnology looks to the next decade’, New Orleans, USA, 20-22 January 1986 Invitation, programmes, Lilly’s manuscript notes, etc. Lilly and UCL colleague Peter Dunnill gave a paper on ‘Biocatalytic Reactions Involving Water-Soluble Organic Compounds’. Workshop Warwick, 5-6 June 1986 Programme, abstracts. Cis-Glycols, Microbial on Production of M.D. Lilly NCUACS 150/7/06 H.39-H.40 Visits and conferences, H.1-H.76 Seventh Australian Biotechnology Conference, University of Melbourne, Victoria, Australia, 25-28 August 1986 Programme and participants. registration form, list of overseas Lilly gave a paper on ‘Lysine production by immobilized cells’. Eighth France, 17-22 July 1988 International Biotechnology Symposium, Paris, 1987-1988 Correspondence re arrangements, programme, lists participants, etc. of Two folders. Lilly particpated in a Round-table on Education. International Quest Challenges Food _ Williamsburg, Virginia, USA, 2-5 October 1988 Symposium Flavor and the for on_ ‘Biotechnology Industry’, Programme only. Correspondence re arrangements, programme booklet. Lilly and J. Woodley gave a paper on ‘Biotransformations of poorly water-soluble organic compounds’. Lilly gave a paper on ‘Biochemical Engineering for Flavor and Food Production’ ‘Opportunities in Biotransformations, Society of Chemical Industry Symposium, Churchill College, Cambridge, 3-5 April 1990 Anglo-lsraeli and Biotransformations, Pembroke College, Cambridge, 25-27 March 1991 Lilly gave a paper on ‘The design of bioreactors for two liquid College, Cambridge, 25-27 March 1991 biotransformations’, Programme with Lilly's manuscript notes on verso. Technology Pembroke Enzyme Meeting on phase M.D. Lilly NCUACS 150/7/06 H.44-H.46 Visits and conferences, H.1-H.76 NATO Advanced Study Institute on ‘Recent Advances in industrial Kusadasi, Turkey, 16-27 September 1991 Biotechnology, Applications of 1990-1992 Correspondence re arrangments and participants report to British Council, typescript of Lilly’s paper, etc. information, lecturers, general arising, and lists of Lilly's Three folders. on ‘The lectured Lilly and Biotransformation The organised by former PhD student of Sukan. Processes’. Design Operation meeting of was F. Vardar- Lilly, Invitations declined 1991-1992 Engineering ‘British Contemporary Museum, London, 27-28 June 1992 History British Since the War’, Conference, Institute of Science for and 21st H.50-H.51 International ‘Harnessing Biotechnology Biotechnology Final programme etc. Symposium the Lilly gave a paper on biotechnology. Letter from organiser, programme, abstracts etc. Mosbach Symposium on Biochemical Technology, Lund, Sweden, 2-5 December 1992 Ninth Exposition Century, Crystal City, Virginia USA, 16-21 August 1992 Contents of folder so inscribed divided into eight for ease Lilly immobilised biocatalysts’. ‘Biotransformations Abstracts, etc. Two folders. 1992-1995 H.52-H.59 ‘Turkey’ paper using gave a on _ M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 of reference: correspondence and papers. i991 from arising correspondence includes NATO Advanced Study Institute (H.44-H.46), and re collaboration between International Institute of Biotechnology (UK) with Ege Biotech-Enzyme network of the Med-Campus programme of the European Commission (coordinated in Turkey), international courses held in Turkey in which Lilly participated, etc. University, Turkey, Izmir, the ‘Visit to TAU [Tel-Aviv University] 1993’ Papers re University research project in biotechnology. in connection with joint UCL / Tel-Aviv visit Includes programme for Biochemical Engineering University, 19-20 May 1993. Joint Advanced Course and Biotechnology, on Tel-Aviv gave a Lily Fermentation’. paper on ‘Engineering Aspects. of For UCL/Tel Aviv C.963A. University collaboration see C.955- of ‘Design and lectured on and Chemical Operation Izmir, Turkey, Industries’, H.61-H.63 Manuscript notes by Lilly Bound volume of lecture notes. are enclosed between pp218 and 219. Lilly Biotransformations for Chemical Synthesis’. Med Campus Course ‘Application of Biotechnologies in Food University Ege Biotechnology Centre, 6-10 September 1993 Synthesis’. Engineering Foundation Conference Recombinant DNA Biotechnology and Engineering Sciences, Deauville, France, 26-21 October 1994 A paper by Lilly and colleagues was given on ‘The Impact of rDNA Technology on Enzymic Carbon-carbon Bond Correspondence re arrangements, programme, abstracts, typescript of Lilly's paper. Three folders. Integration Biological Ill The of M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 H.64-H.66 Med Campus Programme, Turkey, 1995 1994-1995 Contents of untitled folder divided into three for ease of reference: correspondence and papers re this European Biotech-Enzyme. Commission Includes correspondence re in Turkey in which Lilly participated. Project international programme meetings H.67-H.70 International Symposium on Applied Organic Chemistry’, August 1995 ‘Selectivity Jerusalem, Basic in Israel, and 27-31 Correspondence re arrangements, and abstracts, etc. poster, programme Four folders. Lilly gave a synthesis: preparation and use of transketolase’. plenary lecture on ‘Carbon-carbon bond InBio H.73-H.74 Congress, Sydney, Making it Happen’, Biocatalysis: Programme etc. Programme, manuscript notes of proceedings. ‘Recent Advances in Fermentation Technology’, Society of Industrial Microbiology Conference, San Diego, California, USA, 4-7 November 1995 ‘Industrial ‘96 Conference and Exhibition’, UMIST, Manchester, 20-21 February 1996 1994-1996 Lilly agreed to be co-chair of a symposium on integrated bioprocessors with B. Buckland. In the end uncertainty about his health prevented him from travelling to Sydney. Tenth Australia, 25-30 August 1996 International Correspondence re arrangements, programmes, etc. Biotechnology Two folders M.D. Lilly NCUACS 150/7/06 Visits and conferences, H.1-H.76 European Cell Factory Conference, Lund, Sweden, 27-30 April 1997 Book of abstracts. Lilly was an organiser of the meeting. Shorter correspondence and papers re conferences 1997-1998 Includes call for papers for Second European Symposium on Biochemical Engineering Science, Porto, Portugal, 16- 19 September 1998. Lilly was hoping to attend this meeting but died in May that year. Lilly M.D. NCUACS 150/7/06 SECTION J CORRESPONDENCE, J.1-J.22 1966-1998 GENERAL CORRESPONDENCE REFERENCES AND RECOMMENDATIONS GENERAL CORRESPONDENCE 1966-1998 1966-1969 1970-1979 1983-1989 1990-1991 1992-1998 J.6-J.12 J.13-J.16 J.17-J.22 Appointments and promotions REFERENCES AND RECOMMENDATIONS 1968, 1984 Appointments and promotions Grant applications Fellowships and awards 1968-1998 1968-1998 M.D. Lilly NCUACS 150/7/06 Correspondence, J.1-J.22 1994-1995 1997-1998 J.13-J.16 Grant applications 1970-1992 J.13-J.15 1970-1984 1970-1976 Science Research Council / Science and Engineering Research Council 3 folders. Fellowship Engineering Fellowships and awards Academy of 1992-1996 of Engineering / Royal J.17-J.22 J.17-J,19 1989-1992 1991-1996 M.D. Lilly NCUACS 150/7/06 Correspondence, J.1-J.22 J.20-J.21 Royal Society 1991-1992 2 tolders. 1994-1996 M.D. Lilly NCUACS 150/7/06 INDEX OF CORRESPONDENTS AARON, Stuart W. ABBOTT LABORATORIES ABER INSTRUMENTS LTD ACADEMIC PRESS INC. ACEVEDO, Fernando ADVISORY BOARD FOR THE RESEARCH COUNCILS C.237, C.240, C.264, C.816 See also C.239, C.242, C.244 CHC C.267, C.268, C.276, C.292 D.166, D.169, D.174, D.237, D.239 F.293 Rode Jah AGRICULTURAL AND FOOD RESEARCH COUNCIL F.2-F.14, F.359 ALFA-LAVAL ENGINEERING LTD C.44, C.120, C.968 ALLEN, Sir Geoffrey C.237-C.239, F.56, F.65, F.78 See also C.60, C.82, C.930, F.73, F.185 ALLIED BREWERIES (UK) LTD G.1 ALLSOP, Richard E. APCEL LTD ARCHIBALD, Peter ASENJO, Juan A. C.564 871203 D.62 G.2-G.4 D.266 C.758 ALONSO, Francisco José VILIESID ASENJO, Barbara A. ANDREWS- APPLIED MICROBIOLOGY AND BIOTECHNOLOGY AMERICAN INSTITUTE OF CHEMICAL ENGINEERS See C.186 Pi(liteoO; meet incon See also C.50, F.236, F.244, F.251- F.253 C.758 C.236 C.20 C.237, C.238 C.893 BAGLEY, E. BAILEY, James E. ASHLEY, Mike J. ASHWORTH, John Michael D.327, F.49, H.61 BAILLIE, Wensley G. HAYDON- BAKER, Raymond M.D. Lilly NCUACS 150/7/06 Index of correspondents BALASINGHAM, Kangathevy BALL, Christopher BALSTON, A.E. BARBER, Michael BARCLAY, Scott S. BATCHELOR, F.R. BAYER AG BECKMAN INSTRUMENTS INC BEECHAM GROUP LTD BEECHAM PHARMACEUTICALS BEECHAM RESEARCH LABORATORIES C.759, D.92 C.886 G.141, G.153 C.371 See C.670, C.761 C.388 C.758 G.5-G.8, G.13-G.16 G.19-G.33 C.47i 0.237; C.298..G.242,.0 244 C.245, C.306, C.393, C.775, C.943, a also C.236, C.241, C.264 C.388-C.390, C.391, C.775, D.81 BIOCATALYSTS LTD THE BIOCHEMICAL SOCIETY BIOCHEMIE BIOPROCESS ENGINEERING BIORESEARCH IRELAND BELL, Geoffrey H. BIDE, Sir Austin BIOCATALYSIS BIOCHIMICA ET BIOPHYSICA ACTA C.770 c.49 F.195 F141 D.112 D.362, F.149, F.151, F.153 See also C.182, C.183 C.814, D.73, D.101, D.108, D.110, Dat Oi Dii2o,.bali2i, Da3s0) D.133, D136, D162; D.173,; D:235, D.236, D.242, D.264, D.269, D.270, D.278, D.304, D.363, D.364 BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) €.125°G'195-6 207'*©.298: C300; C.760, C.860, C.932, C.962, F.99, F.110 D.86, D.89, D.90, D.92, D.94, D.113, D.133, D.142 BIOTECHNOLOGY AND BIOENGINEERING D.318 F.82 M.D. Lilly NCUACS 150/7/06 Index of correspondents BIOTECHNOLOGY COMPUTER SYSTEMS LTD C.895-C.905 BIOTECHNOLOGY DIRECTORATE See SCIENCE AND ENGINEERING RESEARCH COUNCIL BIOTECHNOLOGY JOINT ADVISORY BOARD (BJAB) F.16-F.28 BIOTECHNOLOGY LETTERS D.213 BIOTRANSFORMATION RESEARCH ADVISORY GROUP F.29 BIRCH, John R. BIRNBAUM, Staffan C237, D.330 BLAKEBROUGH, Norman C.321, C.786, C.827 BLANCH, Harvey W. BLAYER, Simone BLOXHAM, David P. BOEHRINGER CORPORATION (LONDON) LTD A.23 C.762 G.41 D.28 BOSSE, Michael A. C.471 D.318 G.135, G.137 BRESLAU, Barry R. BRIDGEWATER, John BRIGHT, Harold J. BRAUER, H. BRENCH, Alan C.734 D.306 C.763 BRITISH BIO-TECHNOLOGY LTD G.37 C186, 6.795, 6.812, 6,.813),C.627, C.828, C.829, C.831, C.863, C.867, C.886, C.957, C.959, C.961, F.168, H.45, H.54 BRITISH PETROLEUM COMPANY LIMITED BRITISH TECHNOLOGY GROUP C.770, C.824 C.943 BROOKES, lan K. BROWNE, Cedric H. D.229, D.231, D.241 BRITISH GAS PLC C.48, G.34-G.37 BRITISH COUNCIL 6237-69 Index of correspondents M.D. Lilly NCUACS 150/7/06 BUCHHOLZ, Klaus BUCKE, Chris BUCKLAND, Barry Christopher lan BULL, Alan Thomas BU’LOCK, John D. BURLIN, T.E. BUSHELL, Michael E. BUTTERWORTH PUBLISHERS CABRAL, Joaquim M.S. CARLEYSMITH, Stephen Wardle F.140 Foo See also C.769 G4741Ca710. Coie G:723..G.770- C.774, C.863, C.970, D.160, D.286, D.289, D.290, F.246, F.248, G.87, G.88, G.92, G.98, G.102, G.105, Hef SeHs/4 5.1.0 See also D.288, G.95 G337,6.338: D:358. F'167-F:169. F.1/1-F-173; 6.192).F.216. F228) F-233h-243-F 2456. 204 F271), eo. See also C.830, F.145 D.213 F142 F.180 C369" C'3/0 D.262 C234 CAz See MacLEOD CARREA, Giacomo CARRINGTON, T.R. CARVER, Claire J.L. Cr4715,6:951, D290 See also C.264, C.516 CASSON CONDER PARTNERSHIP (Architects) FE o80k.39 EF 56-65. i 62, ede, F128 See also C.183, F.74, F.150, H.56 PGO TON bags C.237, C.544, C.830, C.906, C.907, G.38-G.42, J.5 C.89, C.94, C.94A, C.97, C.103, C.107 CELADA, Franco CELLTECH LTD H.48 F.125 C.516 CELLTECH THERAPEUTICS LTD CHARITY COMMISSION CATTERALL, Peter M.D. Lilly NCUACS 150/7/06 index of correspondents CHAUDHARY, Subhash C. C.241, C.244, C.253, C.264, C.299, ara £ ‘2005 ao OY; CHEETHAM, Peter Samuel James , F.141, F.142, F.154 CHEMICAL ENGINEERING SCIENCE CHEMIE INGENIEUR TECHNIK CHIBATA, Ichiro CHRISTY, Charles CHUA, Miranda CIBA-GEIGY FELLOWSHIP TRUST CLARKE, Patricia Hannah CLARKSON, Brian L. COBIOTECH ,D.124 PO S29ONealA C.339, C.340, C.429, C.944 C.779 J.16 © 995 De. bi214..)0:215 See also F.170, F.223 G37 F.30 COLLINS, Anne Marguerite COONEY, Charles L. COREFIELD) JER: CORNISH, Alan R.H. F.85 F.38-F.132, F.145 COCKCROFT, Vic COCKSHOTT, Andy R. COLEMAN, R.F. F.114 G.48, G.58, G.59 CASfek. 106 See also C.49 C.781 COMMISSION OF THE EUROPEAN COMMUNITIES C.196, C.197 €:470, ©.965, F.52 See also C.930 AS See also F.183 170 See also C.166 CORRIEU, G. CRIPPS, Roger E. C223) C'231,.C:233,.C 234,.C.301 CROOK, Eric Mitchell CROUT, David H.G. D3 B32 See also C.829 M.D. Lilly NCUACS 150/7/06 Index of correspondents DAINTON, Frederick Sydney, Baron DALY, William Howard DART, E.C. DAS, Kumud DAS, MLR. DAVIES, Sir David DAVY McKEE (LONDON) LTD DECKWER, W.-D. DENNIS, John S. 6.63 See also C.61 C.784 Flite, teen eee C.786, D.142 0; Raine See J.5 C.79, C.80, C.93, C.96-C.98, C.106, C.107, C.736 F.85 C1836 246..6:26846:27/76:.6.295 See also C.270, C.296 DERVAKOS, George A. C.787-C.789 C.364, C.471, C.544, C.873 F.287-F.289, F.293-F.295 C.388, C.389 C.218, C.225, C.228 DIXON, Keith DOELLE, Horst W. DONALD, M.B. DORDRICK, Jonathan S. DROZD, Jan W. DSM RESEARCH DUARTE, J.M.C. See C.321 D.333 DOVEEV Ee DOYLE, Peter C.769, C.877, 0.231, D.232, D.241 G50, B65) 66, ke2s3. E234 See also C.237-C.239 hee €.35,,C.61;, 6:84-C:103;,C.41.15; C119; C.127-C.132, C.156;'C.157, Cr09; C166; Cri7S, ©1182, C183, C.208, C.209, C.238, C.269, C.305, C.320, C.369, C.419, C.709, C.716, C.717, C.734, C.770, C.779, C.784, C.786, C.805, C.815, C.827, C.829, C.831, C.841, C.866, C.875, C.930 H.56 See also E.15 DUNNILL, Peter M.D. Lilly NCUACS 150/7/06 Index of correspondents DUVNJAK, Zdravko DREW, Stephen W. DYER, Sir Peter SWINNERTON- EARLE, R.L. ELI LILLY AND COMPANY ELNAWAWY, Amin S. ELSDEN, Sydney Reuben ELSEVIER EXCERPTA MEDICA NORTH-HOLLAND C948:,,D:99,.b.110.. DM'25) Di130, D42.Diiib2: -Dri73, Di225. 5.39, F460 E56) 6.577 F.97.GiovG6, G.9, G.154-G.156, J.1 See also C.12, C.125, C.168, C.170, C.176, C.239, C:790; F.295;G.84, Gu27As 3S D.162 GHis C.384 C.805 C.170, G.43-G.59, J.3 i203 C.321 D.115 ENGINEERING FOUNDATION ELSEVIER SCIENCE PUBLISHERS ELTZ, Robert W. ENFORS, Sven-Olof D.227 C110; Ji F.64 PS7.con ENZYME AND MICROBIAL TECHNOLOGY G 709; D223;9-228, Di229..D.233; D.240, D.251, D.252, D.261, D.262, D.279, D.280, 0.281, D350, D365; F.146 G.36 EUROPEAN SECRETARIAT OF NATIONAL BIOINDUSTRY ASSOCIATIONS EUROPEAN FEDERATION OF BIOTECHNOLOGY (EFB) F.133-F.160 See COMMISSION OF THE EUROPEAN COMMUNITIES EUROPEAN SCIENCE FOUNDATION (ESF) F.161-F.165 F.66 E.R. SQUIBB & SONS, INC. ERTOLA, Rudolph J. EUROPEAN COMMISSION C.770, J.2 D.4, J.4 EVANS, Robert index of correspondents M.D. Lilly NCUACS 150/7/06 FAIRTLOUGH, G.H. FIECHTER, A. FINER, Elliot G. FISH, Neville M. FITZPATRICKS Chartered Patent Agents FLASCHEL, Erwin FLOWERS, Brian Hilton, Baron FLYNN, David Sidney FORRESTER, KETLEY & CO. chartered patent agents FOX, Richard |. FREEMAN, Amihay See C.739 G.6, G.12-G.18 F.143, F.145, F.148 G62 C.792 G.127A J.2 C2793-C: 795; G:956,C.957.C.959; G.961-C.968, D244 'D:245; D296, D3350) 4.67, See also D.348 FURSTOSS, Roland GADEN, Jr, Elmer L. FROUD, Steve FUKUI, S. G.38 See E.15 C224" C228: C231 C.238,.6:234: C970) F140 C.797;C.814, D:73,:D:101, D'108- Dit Dadi, Da25; D27.b\1380, D183; Die6,. D102. D160; D162; D.173, D.181, D.363 See also C.770, D.79. D.95, D.107, BI Tale C.210, F.246 GLAXO GROUP RESEARCH LTD 39 C.785 C.471 F.149, F.151, F.153, F.154 GARCIA, Fernando GASSER, Francis GHOSE, T.K. GLAXO HOLDINGS PLC GOFFEAU, André C2/623F:184),,G:60 C.49 GIST-BROCADES NV M.D. Lilly NCUACS 150/7/06 GOLDIN, Amanda GOLDSTEIN, Walter E. GOMA, G. GOODHEW, Sir Victor Henry GOODWIN, Brian C. index of correspondents F.66, F.68, F.71 H.23 F.98 ealial D.16 GRAND METROPOLITAN BIOTECHNOLOGY LTD F.194, F.195 GRAY, Peter Phillip C.796-C.799, D.104, D.109, F.225, F.246, F.251, H.73, H.74, J.5 See also D.111 GREAT BRITAIN AND NORTHERN IRELAND DEPARTMENT OF EDUCATION AND SCIENCE F.38, F.80 DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH C.321 PARLIAMENT C.275, F395 Boley See F.173 OFFICE OF SCIENCE AND TECHNOLOGY E08) F.39h42 8 tae. 00 DEPARTMENT OF TRADE AND INDUSTRY OVERSEAS DEVELOPMENT ADMINISTRATION Pia Bel G 157,-C:202-€.207,,C.239, €i241, CG 244-C6i250nG 255,,6-258 6 2og; C2983C6.930"F.283F.74-F 81), F.82, F.84, F.90, F.118, F.188, F.189, F.362-F.364 See also F.187 LABORATORY OF THE GOVERNMENT CHEMIST m1 SELECT COMMITTEE ON SCIENCE AND TECHNOLOGY GREENHALGH, M.E. GYLLENBERG, H.G. HOUSE OF COMMONS HOUSE OF LORDS HAGERDAHL, Barbel HAHN- F.48, F.97, F.106-F.111, F.114, index of correspondents M.D. Lilly NCUACS 150/7/06 HALLING, Peter James HAMER, Geoffrey HAMM, Wolf HANSON, Jean HARBOUR, Colin HARDMAN, David J. HARTLEY, Sir Harold HEATH, Sir Edward Richard George HEDEN, Carl-Géran HERBERT, A.B. (Andy) HEWITT, Geoffrey Frederick C802: 4 F.82 G.132, G.133, G.135 D441 2046 C.803 F.182, F.183, F.217, F.222-F.225, F.228-F.231, F.233-F.238, F.240, F.242-F.248, F.250, F.252, F.253, F.287, G.71 See also G.61, G.63, G.66 E2s See also J.1 FabO-Pligas ins H.47 C.345, C.346, H.37A Jake, C.805 HOBBS, Gordon Robert C.806-C.811 HOBBS, R-F. HOLT, Geoffrey HIGGINS, John Joseph HOARE, Michael C.18, C.77, C.79, C.96-C.98, C.100, C.103, C.105-C.110, €.112, C.114, C15,.C 23%, ©.269" @.26S7C 2175, C.279, C.281, C.515, C.543, C.544, C.546, C.547, C.735, C.740, C.970 D.181 GS625R 166) k109) Flyin. uHo, F.182, F.223-F.225, F.238, F.243, F245. F 247 F200 2:04 See also F.222 C.91, C.96, C.98, C.100, C.104, C4107,,C.109; C144 HORNE LEA & PARTNERS (Consulting Engineers) C.89, C.90, C.106 F.178, F.181, F.185-F.187, F.191 See also F.188-F.190 HORNBY, Stephen C.267 HOUGHTON MIFFLIN COMPANY HOOKER, Nigel J. TITCHENER- M.D. Lilly NCUACS 150/7/06 Index of correspondents HUITRON, Carlos HUMPHREYS & GLASGOW LTD HUMPHREYS, Gwyn ICl BIOLOGICAL PRODUCTS / IC! BIO PRODUCTS AND FINE CHEMICALS (see also ZENECA BIOPRODUCTS) IC] FIBRES ICl PHARMACEUTICALS IC] SEEDS IMPERIAL CHEMICAL INDUSTRIES PLC INGEMANSSON, Torbjoern INGRAM, David J.E. INSTITUTE OF BIOLOGY INSTITUTION OF CHEMICAL ENGINEERS C.812-C.814 186 G.83, G.84 F.56, F.57, F.59, F.61, F.64, F.66, Fe lek 2 G 289-6 24126: 244.6 253; G258..G.264..6:.27.5,.67290, 37 C.943 GAM F.17 C.50, C.337, C.345, C.346, C.877, F.181, F.185-F.189, F.191 See also C.236 C235 F.172 See also F.173 F.166-F.271 Od H.48 INSTITUTE OF CONTEMPORARY BRITISH HISTORY INTERNATIONAL COUNCIL OF SCIENTIFIC UNIONS (ICSU) F.273-F.295 INSTITUTE FOR BIOTECHNOLOGY STUDIES (IBS) / INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY (IIB) A.7-A.9, C.709, C.716, C.731, C734 i736; C.730,C.868, C876, D.33, D.65, D.118, D.300, D.320, 20g ole F.278 INTERNATIONAL ORGANISATION FOR BIOTECHNOLOGY AND BIOENGINEERING (IOBB) INTERNATIONAL UNION OF PURE AND APPLIED BIOPHYSICS (IUPAB) INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY (IUPAC) JAG F.273-F.295 Be2rt INTERNATIONAL FOUNDATION FOR SCIENCE M.D. Lilly NCUACS 150/7/06 ISENBERG, Don L. ISON, Andrew Phillip Index of correspondents J.A. KEMP & CO. Chartered Patent Agents JACKSON, Robert JANSON, Jan-Christer JANSSEN, Dick B. JANSSEN, Frank J. JENE, Quitz JENKINS, Nigel JOHN & E. STURGE LTD JOHN BROWN ENGINEERS AND CONSTRUCTORS LTD G.5, G.6, G.7, G.8, G.14 See also G.13 C.101, C.106-C.109, C.112, C.369-C.371, C.834, C.907 C.120, C.462-C.464, C.466-C.470, C.943, G.129, J.4 F.67 C:815 6.228, C.233,. 6.235 C.816 C.396, C.397 Fa G.130 C.236 C.264 D.101, D.110, D.180, D.181 JOHN, Chris S. JOHN WILEY & SONS, INC. JONES, Carys WRIGLEY- JONES, Richard Rhys JOURNAL OF CELL SCIENCE See C.883 C.816-C.822 D.342, D.343 D.41, D.46 JOURNAL OF BIOTECHNOLOGY JOURNAL OF GENERAL MICROBIOLOGY G.47, G.48 D.46, D.147, D.148, D.216 See also D.214, D.215 KATZIR, Ephraim KATCHALSKI- KENNEDY, John F. KESHAVARZ, Tajalli KINZEL, Jerry J. G.218,. C225, 67284 F.73 See also F.74 C.955, C.956, C.958, F.31, F.36 D.223, D.228, D.229, D.233, D.234 KARUTZ, Martin KASTNER, Gunther SCHMIDT- C.825 M.D. Lilly NCUACS 150/7/06 Index of correspondents KLOOSTERMAN IV, Jan C.826, D.236 KNOWLES, Chris J. KONECNY, J. KONINGS, W.N. KOSSEN, Nico KUNZE, Robert J. L.H. ENGINEERING COMPANY LTD LAGES, Ana Christina Argolo LAURENCE, Mark B. LEAK, David LEGGE, Paddy LESEIEY RB: LEVERHULME TRUST ,C.924 , C.829, J.3 “€.269),6:270; C7296 B.1 C.930 C.50 C.234 LILLEY, Gerald LILLFORD, Peter J. LILLY, Sheila E. LILLY INDUSTRIES LTD LIGHTHILL, Sir (Michael) James C.244, C.258 See C.241, C.242, C.261, C.930 C.516, C.830, C.906, C.907, G.2, G.3, G.41, J.5 Gi244C.26)-6.48:.€'60..C oi, Cro, C.60-C.63, C.79, C.80, C.84, C.152, C.384, C.942, C.947, C.948 See C.892 LIMON-LASON Y ROLDAN, Alberto Jorge C.837 C.831 F.108 F.142 LINDAHL, Ulf LINKO, Pekka LITTLECHILD, Jennifer C.778, D.358 LOWE, C.R. M.D. Lilly NCUACS 150/7/06 LUYBEN, Karel Ch. A.M. LYBERATOS, Gerasimos MACALONEY, Graeme McDOUGALL, Barbara M. MACLEOD, Claire J.L. MACRIS, Basil J. MARCONI, Walter MARLOW FOODS LTD MARSHALL, Carolyn MARTEN, Neil MARTIN, Juan F. MATTHEW, Gavin B. Index of correspondents F.39-F.42, F.44, F.45, F.49, F.51, Fio2, F00; fo} ie 10d OS ate a1O5 F.53 J.3 J.3 C.832, D.148 F.38) &-59 a | C.471 C.833, C.863 Raliad F109 C.834, C.835 C.53 C.919 MICHAELS, Alan S. MOORE, Eli KESHAVARZ- MAY & BAKER LTD MEAD RESEARCH USA MEADOW, Pauline M. Cr /8) ri C.396, C.397 D.48, D.148 MEDICAL RESEARCH COUNCIL MATTHEW HALL NORCAIN ENGINEERING LTD MATTHEW HALL ENGINEERING (SOUTHAMPTON) LTD MERCK SHARP & DOHME RESEARCH LABORATORIES C.48, C.361 C.773, C.970, G.86-G.127, J.10 See also C.54 MOSQUIERA, Fernando Guillermo MUKHERJEA, R.N. MULLIN, John W. F.78, F.85 C.836 D.33 C.103, C.109, C.114 C813; DOO 7h 3/ MOSBACH, Klaus MOSER, A. J.4 H.23 M.D. Lilly NCUACS 150/7/06 MUNRO, Peter MUTH, W.L. Index of correspondents NATIONAL ECONOMIC DEVELOPMENT OFFICE F.168 NATIONAL RESEARCH DEVELOPMENT CORPORATION C.305-C.320, C.322, C.393-C.395, C.943, G.9-G.11, G.14 NATURE NEALE, Stella NIELSEN, Jens NOVO INDUSTRI A/S NOVO NORDISK A/S NUESCH, Jakob NUFFIELD FOUNDATION D.30, D.259 C.513-C.515 F.60,-R:o0 G:709.6 71046 8147 EF. 4404E-143 See also G.127A C.195 F.247 109: eal NYIRI, Laszlo OSHIMA, Yasuji PACKER, Helen L. PALFREY, R.N. C.837 C.877 C.838-C.840 OATLEY, Geoff. E. OLATUNJI, Francis O. O'NEILL, Sean P. OSSEWEINER, Patricia OROS INSTRUMENTS LTD C.841 C275 D.104 C.195, C.196 FOt-r OS Foo males: ROO wate See also F.114, F.162 C.465, J.11 See also C.842-C.847 PALL PROCESS FILTRATION LTD PANLABS INCORPORATED C.848 C.886 C.849 PARK, R.J. PEDERSON, Sven C.97, C.968, J.3 M.D. Lilly NCUACS 150/7/06 Index of correspondents PERGAMON PRESS D.298-D.300 PFIZER INC PFIZER LTD PHARMACIA BIOPROCESS TECHNOLOGY AB PINES, Seemon H. PIRTRio od: PLENUM PUBLISHING CORPORATION PORTON INTERNATIONAL LTD POSTE, George POULSEN, Poul Berge POWELL, Keith A. , C.404, C.471, C.873, C.877, C.803 D.120 C.896 C.968 F.139; F.141, F.142 Sar F.293 F.109, F.110 PREEZ=IG DU PRIEELS, Anne-Marie C/1640 24) Di27 Di3437 4 PUHLER, A. PYE, E. Kendall PROCESS BIOCHEMISTRY R.T.Z. CHEMICALS LIMITED D.120, D.121 See also D.175 QUEST INTERNATIONAL FLAVORS USA INC. C:237, E65 H.41 F.293 G.130 C.798, C.853 C.850, C.851 D.266 G.38-G.40 REHM, H.-J. RHODES, P.M. REGAN, Dennis Louis QUINTERO, Rodolfo RALPH, Bernard J. RICHARDS, Brian M.D. Lilly NCUACS 150/7/06 Index of correspondents RICHMOND, Sir Mark (Henry) RICHMOND, William RICKARD, Pamela A.D. C7064 See also F.357 C85teC 852 4):2 Gi853 ROBERTS, McLENNAN & CO. Chartered Accountants G.141-G.144 ROBERTS, Sir Derek Harry ROBERTS, Stan M. ROBINSON, Peter J. RODGERS, Peter J. ROKEM, J. Stefan ROLZ, Carlos E. C.51*G:88) Cul56 6.170, 6.238; C.878 See also C.239, C.961, C.962 C.208, C.209, C.403, C.404, C.420, C.760, C.860, J.4 C.854 C.345 See also C.236, C.237 299 00) i210 2O0h be 2old bos, F.284-F.294 C.855 F.168 ROYAL SOCIETY RUSSELL, Andrew J. ROWE, Peter N. ROWLANDS, Robert T. C.886 J.18, J.19 ROOKE, Sir Denis Eric ROSEN, Natasha C48 C56, €C.125, F.1,.G.34°G.35 ROYAL SOCIETY OF CHEMISTRY ROTHSCHILD, Nathan Mayer Victor, Baron C.388-C.390, C.391, C.770, C.801, J.18 ROYAL ACADEMY OF ENGINEERING (see also FELLOWSHIP OF ENGINEERING) C.57 SALLIS, Paul J. SANO, Yoshiki G.64 J.2 .90; on SARRA, Montserrat SASAKAWA FOUNDATION C:996)-1725 0:20; J721 C.961 C.856, G.44-G.47, G.55 M.D. Lilly NCUACS 150/7/06 SAUKKONEN, Jussi J. Ac ot A NS kes CULE Ae Vibes SAYED, Asad SAYGIN, Erdal SCHUGERL, Karl Index of correspondents 3 aL 297, 391, C.393, D. G.30 See also C.236, C.239, C.241, C.244, G.19, G.20 C.268, C.295, C.296 F.62 F.59, F.64 C:9)G 165; ©1770), C1767 6.238) C.242, C.293, C.321- C.375, C.420, C.423, C.734, C.775, C.808, C.816, C.859, C.923, C.952-C.954, C.968, F.64eh 72.6. Olah. d20F:ooo- F.367, J.13-J.15 SCIENCE RESEARCH COUNCIL / SCIENCE AND ENGINEERING RESEARCH COUNCIL (including BIOTECHNOLOGY DIRECTORATE) SENDO, Takashi SHAMLOU, Parvis Ayazi C.857 D.306 SHATZMILLER, Shimon SIMMONS & SIMMONS H.67 C.769 C.247, C.259, C.805 SHELL RESEARCH LTD SIMPSON, T.J. SINCLAIR, J.T. SIEFF, Marcus Joseph, Baron C.877 C62 G.114 SHELL VENTURES U.K. LTD SHELL BIOSCIENCES LABORATORY SHELL INTERNATIONAL PETROLEUM COMPANY LTD C.240, C.264, C.294, C.769, C.816 See F.185, F.187, F.189, F.191 C.58, C.968 SMITH KLINE & FRENCH LABORATORIES mZ10 e274 C.240, C.471 SLATER, J. Howard SLATER, Nigel K.H. SMITH, Harry H.67 A.13 J.20 SKRYABIN, Konstantin iO GO2ni oo, beoo M.D. Lilly NCUACS 150/7/06 Index of correspondents SMITH KLINE BEECHAM PHARMACEUTICALS SMITH KLINE BEECHAM PLC C.245, C.246, C.249, C.250, C.258- C.260, C.264, C.299, G.33 SOCIETY FOR GENERAL MICROBIOLOGY D.48, F.180 SOLA, Carles SOLANO, Armando Ochoa SPARGO, Peter L. SPIER, Raymond E. STOCKAR, Urs von STONES, Rachel STREET, Graham F.64, F.66, F.103 C.836 C.404, C.877, C.945 See also C.364, C.760 D.251, D.252, D.261, D.262, D.279, D.280, D.281, D.350 D:234-F 145: F146 See C.860 Goo SUKAN, Fazilet VARDAR- SUKAN, S. Suha SUPHANTHIKRA, Manop TAMPION, J. TANNENBAUM, Steven R. C.398-C.401 C.862-C.865 SUMITOMO CHEMICAL COMPANY JAPAN F.222, H.44, H.45, H.52-H.54, H.56- H.58, H.65, H.66 C36, 6868, F.2238-F 2336234: H.44, H.45, H.52-H.54, H.56-H.58, H.64, H.65 See also F.287 C.866 TATE & LYLE GROUP RESEARCH & DEVELOPMENT THOMAS, Colin R. THOMAS, Daniel THOMAS HARRIS & ASSOCIATES ele C.338 Ri67 al C.80 THATCHER, Margaret Hilda, Baroness D.95 See also C.829 C.461, C.467, C.930, D.293 TIMMIS, K. M.D. Lilly NCUACS 150/7/06 TRAMPER, Johannes (‘Hans’) TURNER, Mike K. TURNER, Nicholas J. UHLEN, Matthias UNESCO UNILEVER PLC Index of correspondents C4276 540"6. 544 C.418, C.969 See also C.424 See C.892 Pee: G.242.-€.248 6.258 UNILEVER RESEARCH / UNILEVER RESEARCH AND ENGINEERING G.237.,.6.239, C244. €.265, C299: CGi54a.6 930, F181 F166 See also F.185, F.187, F.188, F.189, F.191 UNILEVER RESEARCH LABORATORIUM VLAARDINGEN C.240, C.295, C.471, C.930 UNIVERSITY GRANTS COMMITTEE ©2456:376-6.38/ VARDAR, Fazilet VILLADSEN, John WARD, John Maxim UNIVERSITY OF CAMBRIDGE F.368-F.370 W.R. GRACE & CO. WANDREY, Christian WANG, Daniel I.C. See SUKAN E110 See ALONSO Rod -89 VERRIPS, T. VILIESID C.321, D.4 D.181, D.235, D.236, D.242, D.264, D269) D270 318) rie/ C2377 6.404 See also C.200 WARBURTON, David WARREN , Simon WEBB, F.C. Gii97 E109 C.872, D.92 D.318 M.D. Lilly NCUACS 150/7/06 index of correspondents WELLCOME BIOTECHNOLOGY LTD C687 6:345 Cais WHATMAN BIOCHEMICALS LTD G; 318,6:413,G6141-G.156 WHEATLEY, Margaret WHELAN, W.J. WIJFFELS, Rene WILLETTS, Andrew WILLIAMS, Angela WILLIAMS, Roger WINGARD, Jr, Lemuel B. WITHOLT, Bernard WOHLGEMUTH, Roland WOLFSON FOUNDATION €.875 E30 D.324 G.233.6:234.-C 404. €:760 de? F.108 D.99, D.101 See C.218 G225 G5ile G 63-6 82°F l/2ae 73. Peo (ae bea 2 See also C.88 WORSWICK, Richard WUBBOLTS, Marcel G. WUTHRICH, K. WOODLEY, John Michael WYETH LABORATORIES INC. Gr126) C166, G 196, C:260; 6.398) 401, C403: 6.4167 C.717-C.762, C763. 6809, C8226 B77 .B.310: D32076.3883H./1 See also C.197, C.396, C.397, C.424 iai'0 YOUNG, T. GRAY YUSUF, Helena WYKES, John Richard YABUSAKI, Yoshiyasu M.D. Lilly NCUACS 150/7/06 Index of correspondents ZAMBIA SOCIETY FOR GENERAL MICROBIOLOGY F.291 ZENECA BIO PRODUCTS ZENECA SEEDS C.264, C.295, C.299, C.423, C.907 F.20