CLARKE, Patricia Hannah

CLARKE_PATRICIA_HANNAH

Catalogue of the papers and correspondenceof Patricia Hannah Clarke FRS (b. 1919) by Timothy E. Powell and Peter Harper NCUACScatalogue no. 120/6/03 P.H. Clarke NCUACS 120/6/03 Title: Catalogue of the papers and correspondenceof Patricia Hannah Clarke FRS (b. 1919), biochemist Compiled by: Timothy E. Powell and Peter Harper Description level: Fonds Date of material: 1963-2003 Extent of material: 9 boxes, ca 260 items Depositedin: Special Collections, University College, London Reference code: GB0103P.H. Clarke papers © 2003 National Cataloguing Unit for the Archives of Contemporary Scientists, University of Bath. NCUACScatalogue no. 120/6/03 P.H. Clarke NCUACS120/6/03 The workof the National Cataloguing Unit for the Archives of Contemporary Scientists in the production of this catalogue is madepossible by the support of the following societies and organisations: The British Computer Society The British Crystallographic Association The Geological Society Girton College Cambridge TheInstitute of Physics The Royal Society The Royal Astronomical Society The Royal Society of Chemistry St John’s College Cambridge Trinity College Cambridge The Wellcome Trust P.H. Clarke NCUACS120/6/03 NOT ALL THE MATERIAL IN THIS COLLECTION MAY YET BE AVAILABLE FOR CONSULTATION. ENQUIRIES SHOULD BE ADDRESSED IN THE FIRST INSTANCE TO: SPECIAL COLLECTIONS THE LIBRARY UNIVERSITY COLLEGE LONDON P.H. Clarke NCUACS120/6/03 LIST OF CONTENTS GENERAL INTRODUCTION Items Page SECTION A BIOGRAPHICAL A.1-A.33 SECTION B WOMENIN SCIENCE B.1-B.48 SECTION C PUBLICATIONS AND LECTURES C.1-C.54 SECTION D SOCIETIES AND ORGANISATIONS D.1-D.25 SECTION E VISITS AND CONFERENCES E.1-E.36 SECTION F CORRESPONDENCE F.1-F.78 INDEX OF CORRESPONDENTS 15 22 29 34 40 52 P.H. Clarke NCUACS120/6/03 GENERALINTRODUCTION PROVENANCE 5 The papers were received from Professor Clarke in 2002. OUTLINE OF THE CAREER OF PATRICIA HANNAH CLARKE Patricia Hannah Green was born in Pontypridd, South Wales on 29 July 1919. She attended Coedpenmaen Elementary School and in 1930 was awarded a scholarship to the County Grammar School. She did not take this up since in the same year she had been awarded a Foundation Scholarship to Howell's School Llandaff. She went up to Cambridge in 1937 to read Natural Sciences, having obtained a place at Girton College. Later she was awarded a scholarship in Chemistry. She studied Biochemistry for Part Il of the Natural Sciences Tripos but in the summer of 1940 she relinquished a research scholarship in order to take up war work. Her first post was in a branch of the Armament Research Departmentof the Ministry of Supply that had been evacuated to the University of Wales in Swansea. Later she was transferred to Woolwich Arsenal to continue her work on new explosives. In 1944 she was able to leave Woolwich and to take a post as Research Assistant to B.C.J.G. Knight at the Wellcome Research Laboratories in Beckenham, Kent. His work at that time was concerned with pathogenic anaerobic bacteria that cause severe infections of war wounds. In 1940 she married Michael Clarke. He joined the Army in 1940 and became a Tank Commander, serving in the Western Desert, India and the Middle East. When the war ended he returned to England and after being demobilised he became a documentaryfilm director. They had two sons; Francis born in 1947 and David born in 1949. Clarke continued to be involved in microbial biochemistry but decided to take a few years awayfrom full-time employment. In 1951 she joined S.T. Cowan to workpart-time at the Medical Research Council National Collection of Type Cultures based at the Central Public Health Laboratory in Colindale, London. This was a productive period during which she devised micromethods for identification of bacteria using enzyme reactions. When the MRC suggested she should workfull-time she thought that in that case she might moveon. In 1953 Clarke was appointed to an Assistant Lectureship in the Department of Biochemistry at University College London with a special responsibility for Microbial Biochemistry. She remained at University College Londonfor the rest of her career, being promoted to Lecturer in 1956, Reader in 1966 and Professor in 1974. On retirement in 1984 she was appointed Professor Emeritus of the University of London. In 1996 she was elected an Honorary Fellow of University College. She was P.H. Clarke NCUACS 120/6/03 6 also Honorary Lecturer in the Genetics Department of Monash University Australia in 1971, Honorary Professorial Fellow of the University of Wales Institute of Science and Technology 1994-1987 and Royal Society Kan Tong-Po Professorat the Chinese University of Hong Kong 1986. Clarke had many other professional commitments. She served on the Council of Society for General Microbiology 1960-1970, the Executive Committee of the Biochemical Society 1978-1981 and the Council of the Freshwater Biological Association 1980-1984. Clarke also was a memberof the Science Board of the Science Research Council (1979-1984), the Governing Body of Wye College (1980-1986), the Council of the London School of Hygiene and Tropical Medicine (1982-1984) and the Council of the University of Bath (1987-1993). Other commitments included the British National Bibliographic Research Fund 1990-200 and, locally, the Council of Cheltenham Ladies College (1984-1990) and Board of Governors of Deer Park School, Cirencester 1988-1999. In correspondence with C.M.C. Haines regarding her entry in Haines’s book /nternational Women in Science (Oxford, 2001), Clarke summarised her scientific work as follows: ‘Clarke’s main research, with her students and colleagues, was on the properties and the evolution of bacterial enzymes. By selecting mutants with the ability to grow on novel substrates they obtained strains producing altered enzymes, altered transport systems and altered regulatory systems. They werethe first to show that a single site mutation could result in altered substrate specificity. They also showed that a range of novel enzymes could evolve from successive single site mutations. She also collaborated with biochemical engineers in research on methods for producing and purifying bacterial enzymes for industrial use and becameinvolved in developments in biotechnology’. For her contributions to microbial biochemistry, Clarke was elected to the Fellowship of the Royal Society in 1976 (LeeuwenhoekLecture 1979), serving on Council and as Vice-President 1981-1982. DESCRIPTION OF THE COLLECTION The material in this collection is presented in the order given in the list of contents. It covers the period 1963 to 2002, although the bulk of the material dates from the 1980s and 1990s. Section A, Biographical, includes autobiographical material compiled and assembled in connection with her Personal Record as a Fellow of the Royal Society, a full curriculum vitae and an transcript of her video-tape interview for the Biochemical Society. There is also documentation of a number of the later honours she was accorded. Clarke’s interest in school education in general and science teaching in particular, is documented, with papers relating to Deer Park School Cirencester of which Clarke was a Governor 1988-1999. Her concern for education is also reflected in her P.H. Clarke NCUACS 120/6/03 7 correspondence with local and national politicians, although other topics are covered including tobacco advertising and the treatment of asylum seekers. Section B, Women in Science, documents both Clarke’s interest in the historical contribution of womenscientists, and her concern to ensure that more women becamescientists and that their career prospects were the same as those of their male colleagues. The material, which includes correspondence, notes, printed reports and photocopied background material, was assembled by Clarke in connection with a number of specific activities: her 1991 lecture ‘Women in Science at University College 1878-1978’; a Royal Society meeting on ‘Women in Science and Technology: opportunities for change?’, 28 May 1993; her service on the Committee on Womenin Science, Engineering and Technology established in 1993 by William Waldegrave MP, Minister for Public Service and Science, whose report ‘The Rising Tide’ was published in 1994; and a meeting on Womenin Scienceat the Royal Society, 27 March 2001. Section C, Publications and lectures, documents a few of Clarke’s publications from the 1980s on. The largest components relate to her Royal Society Biographical Memoirs of colleagues Roger Yate Stanier and Malcolm Douglas Lilly and her entry on Muriel Robertson for the New Dictionary of National Biography. There is also an incomplete set of offprints of her work. Lectures material includes documentation of her 1979 Royal Society LeeuwenhoekLecture ‘Experiments in microbial evolution: new enzymes, new metabolic activities’ and the 19th J.D. Bernal Lecture on ‘New directions in biology: basic science and biotechnology’, delivered at Birkbeck College London, 1988. Section D, Societies and organisations, is not extensive. There is material relating to eight UK and overseas organisations, including (UK) the British National Bibliographical Research Fund and the Royal Society, chiefly its Archives Working Group and Library Committee, and (overseas) the Palm Oil Research Institute of Malaysia and the Research Grants Council of Hong Kong. The material spans 1975-2001. Section E, Visits and conferences, covers some of Clarke’s travel and attendance at meetings over the period 1971-1998, although the earlier entries are later (c 1998) typescript accounts compiled by Clarke from her diary entries. Of particular significance is the documentation of her visits to the Far East through the 1970s, 1980s and 1990s, including Singapore, Malaysia (in connection with the Palm Oil Research Institute) 1990-1992, China and Hong Kong. Thereis also material relating to her involvementin two 1992 meetings marking the centenary of the birth of J.B.S. Haldane. Section F, Correspondence, is the largest in the collection. The bulk of this material was arranged by Clarke by group of correspondents and then further subdivided by individual correspondent, andit has been retained in this original order. There are groups of correspondence with her fellow researchers at University College London, with colleagues in the UK and with fellow scientists in the P.H. Clarke NCUACS120/6/03 8 USA and Europe. Few correspondents are represented by extended exchangesofletters, the exceptions being R.E. Drew and B.W. Holloway. Other correspondents include S. Brenner, H.L. Kornberg, R.D. Sager and R.Y. Stanier. Thereis also an index of correspondents. ACKNOWLEDGEMENTS Weare very grateful to Professor Clarke for making the papers available and for information and advice received. Timothy E. Powell Peter Harper Bath, June 2003 P.H. Clarke NCUACS 120/6/03 SECTIONA BIOGRAPHICAL,A.1-A.33 1976-2001 A.1-A.17 BIOGRAPHICAL AND AUTOBIOGRAPHICAL A.18,A.19 PERSONAL CORRESPONDENCE A.20-A.31 EDUCATION ISSUES A.32,A.33 POLITICS A.1-A.17 BIOGRAPHICAL AND AUTOBIOGRAPHICAL 1977-2001 A.1, A.2 ‘CV Personal Record for Royal Society etc’ 1999 Contents of Clarke’s envelope soinscribed. Autobiographical account compiled by Clarke for the author of her Biographical Memoir. A.1 A.2 ‘Personal Record’ 37pp typescript autobiographical account. Curriculum vitae; notes on their careers list of Clarke’s Ph.D. students with A.3-A.6 Autobiographical video recording for the Biochemical Society 1993-1995 As part of the Biochemical Society's programmeof video- taped interviews with leading biochemists, Clarke was interviewed by J. Gareth Morris at University College London on 10 May 1994. A.3, A.4 ‘Video recording for the Biochemical Society 1994 (1)’ 1994 Draft typescript text with later manuscript additions. 2 folders. P.H. Clarke NCUACS 120/6/03 10 Biographical A.5 A.6 A.7 A.8 ‘Correspondence re Biochemical Society video recording 1994 (2)’ 1993-1995 Correspondence re arrangements for arising therefrom. interview and Typescript outline of contents of video recording Lists of ‘Published papers 1947-1992’ and ‘Some key papers and reviews’ Two autobiographical notes These typescript notes, written in July and August 2001 refer respectively to Clarke’s biochemistry students from 1960 (prompted by receiving a postcard from one of the former students), and to the circumstances behind her appointmentto a Chair at University College London. 1994 1992 2001 A.9 Typescript accounts of research 1980, 1981 1980 account prepared for ‘Academic innovation’ series on research at University College London during the 1970s; 1981 reports preparedfor visit to UCL of Science Research Council Visiting Group. A.10 entry Biographical International Women in Dictionary to 1950 (ABC-Clio: Oxford, 2001) prepared Science: for C.M.C._ a Haines, Biographical 2000-2001 Correspondence;biographial information sent to Haines; draft of entry. A.11 ‘“Secret”life of scientist Pat’ 2001 Photocopy of profile by Di Alexander, Wilts & Glos. Standard, 1 March 2001. A.12 Letter re post of Principal, Queen Elizabeth College, University of London 1977 P.H. Clarke NCUACS 120/6/03 11 Biographical A.13 Award of Leverhulme Trust Emeritus Fellowship 1984, 1987 Correspondence; reports on grant. Clarke was awarded a grant for research on gene structure and function in Pseudomonasaeruginosa. A.14 Correspondence re nomination of Clarke for appointment as Dame Commander of the British Empire 1984, 1985 Clarke declined the honour. A later (1985) note records her reasons for so doing and the note is annotated in 1998 with an indication that Clarke had not altered her views. A.15 A.16 A.17 Award of Honorary Degree, Canterbury, July 1984 University of Kent at 1984 Brief correspondencere arrangements. Award Academic Awards, May 1990 Honorary of Degree, Council for National 1989-1990 Correspondencere arrangements. Election to Honorary Membership, Society for General Microbiology, 1996 1997 Biographical 1997. outline from ‘SGM Quarterly’, February A.18, A.19 PERSONAL CORRESPONDENCE 1976-2000 A.18 ‘Personal misc correspondence’ 1976-2000 Letters chronological order. of congratulation, personal news, etc. In P.H. Clarke NCUACS 120/6/03 12 Biographical A.19 Correspondencewith Sir Frederick Warner and R.F. Bud, Science Museum, re preservation of historic acetone fermentation plant at former Royal Naval Cordite Factory, Holton Heath, Dorset 1994 A.20-A.31 EDUCATION ISSUES 1978-1997 Clarke had a longstanding concern for the quality of school education. She supported the comprehensive system of education and had a particular interest in science teaching in schools. She served as a Governor (Vice-Chairman) of Deer Park School, Cirencester 1988- 1999 and waschairmanofits curriculum committee. A.20-A.25 National school education policies A.20 Correspondence 1978-1997 1991-1997 Chiefly correspondence with Secretaries of State of the Department of Education and Science (successively the Department for Education and the Department for Education and Employment) re issues in comprehensive school education. A.21-A.24 Newspaper cuttings and other background information on education policy 1978-1996 4 folders. A.25 Correspondence Gloucestershire re education spending in 1992-1995 A.26-A.29 Deer Park School, Cirencester 1992-c1999 A.26 ‘Science in schools’, 2pp typescript account by Clarke of her association with Deer Park School; miscellaneous material re her last meeting as a governor c 1999 P.H. Clarke NCUACS 120/6/03 13 Biographical A.27 Opening of new Science Block, 1991 1991 At Clarke’s suggestion Richard Dawkins, Reader in Zoology, University of Oxford, was asked to perform the opening ceremony. He accepted and the building was opened on 21 April. Correspondence welcome; photocopies of newspaper coverage. Dawkins; with Clarke’s words of A.28, A.29 School science projects 1992-1997 2 folders. Deer Park School, partly prompted by Clarke, initiated a numberof science projects. One, in conjunction with the University of Bath, was a large scale study of ant behaviour (1994). A.30 Stratford-upon-Avon GrammarSchoolfor Girls 1993 Correspondence and papers re opening of school science laboratory by Clarke, 30 September 1993. A.31 Miscellaneous correspondence on education issues 1993-1996 A.32, A.33 POLITICS 1986-1999 Correspondence with various government ministries and Clarke’s local MP re various issues. In chronological order. Clarke was a long-standing memberof the Labour Party. A.32 1986-1992 Includes Clarke’s criticisms of use of British bases for US attack on Libya, 1986, and of proposal to close remaining UK coal mines, 1992. P.H. Clarke NCUACS120/6/03 14 Biographical A.33 1993-1999 Clarke’s Includes tobacco advertising 1993-1995, and criticisms of treatment of asylum seekers 1995. ban support for a on_ P.H. Clarke NCUACS 120/6/03 15 SECTION B WOMENIN SCIENCE, B.1-B.48 1979-2002 Clarke’s This is the one of the larger sections in the collection and documents both historical contribution of women scientists and her concern to ensure that more women became scientists and that their career prospects were the same asthose of their male colleagues. interest in the The material was chiefly assembled by Clarke in connection with a number of specific activities: her 1991 lecture ‘Women in Science at University College 1878- 1978’; a Royal Society meeting on ‘Womenin Science and Technology: opportunities for change?’, 28 May 1993; her service on the Committee on Womenin Science, Engineering and Technology established by William Waldegrave in 1993, whose report ‘The Rising Tide’ was published in 1994; and a meeting on Womenin Science held at the Royal Society, 27 March 2001. The bulk of the material was found in Clarke’s envelopes. These formed a sequence running from A1 to F. This arrangement has been retained and the inscriptions on the envelopes are reproduced in the catalogue entries. At the end of this sequence is material found separately. B.1-B.3 ‘Women in ScienceA1 [...] General Reports’ c 1990s Printed and photocopied typescript reports, papersetc. 3 folders. At B.1 is Clarke’s typescript list of reports in A1. The list doesnotinclude all the material found. B.4-B.7 ‘Women in Science A2. Scientists’ c 1990s Printed and photocopied typescript reports, papers etc on individual women scientists. B.4 Individual womenscientists, A.-H. Material on M. Anning, A. Arber, J.B. Burnell, C. Haslett, D.M.C. Hodgkin. P.H. Clarke NCUACS 120/6/03 16 Women in science B.5 B.6 Individual women scientists, |.-S. Material on E.M. Inglis, K. Lonsdale, M. Rothschild, M. Somerville, M. Stephenson. General contributions Material particular scientific disciplines. contributions on by women scientists to B.7 Academic performance of women at university 1994 Letter from N.G. McCrum, enclosing copy ofarticle, with Clarke’s reply. B.8-B.11 ‘Women in Science B1. UCL Historical’ 1979-1991 B.8 B.9 B.10 Material on position of women academics, particularly scientists, at University College London. At B.8 is Clarke’s typescript list of papers in B1 and B2. The list does not include all the material found. Typescript drafts and printed copy of Clarke’s lecture ‘Womenin Science at University College 1878-1978’ Correspondence re Clarke’s lecture ‘Women in Science at University College’ Draft report and related material on equal opportunities at University College London 1991 1991 1984 Printed and photocopied material on women scientists at UCL c 1979 B.12-B.15 ‘Women in Science B2. UCL scientists’ c 1990s P.H. Clarke NCUACS 120/6/03 17 Womenin science B.12 Lists of women UCL science graduates 1878-1905 and women Fellows of the Royal Society; manuscript notes and photocopied material on womenscientists B.13, B.14 Printed and photocopied material relating to Kathleen Lonsdale 2 folders. B.15 Photocopied material relating to Agnes Arber B.16-B.19 ‘Women in Science C. Meeting at Royal Society 1993’ 1993 Papers re Royal Society meeting on ‘Womenin Science and Technology: opportunities for change?’, 28 May 1993. Clarke chaired the panel discussion at the meeting and helped compile the final report. One of the features was a questionnaire handed out to those present; the results wereanalysed in the report. Programme; handout presented by J.B. Burnell Spiral boundfinal report of the meeting Typescript reports on the meeting by J. Mason, P. Nuttall and C. Turley Questionnaires on women in science B.16 B.17 B.18 B.19 B.20-B.24 ‘Womenin Science D1. The Rising Tide. Publications’ 1992-1994 This material and that in D2 (B.25-B.28) relate to Clarke’s service on the Committee on Women in Science, Engineering and Technology, set up by W. Waldegrave MP, Chancellor of the Duchy of Lancaster and Minister for Science, in 1992. It was established following on from the government White Paper ‘Realising our potential: a strategy for Science, Engineering and Technology’ Cmnd /. P.H. Clarke NCUACS120/6/03 18 Womenin science B.20 B.21 B.22 B.23 2250 (1993). The Committee’s report ‘The Rising Tide’ waspublished in 1994. Copy of ‘Realising our potential: a strategy for Science, Engineering and Technology’ Cmnd 2250 (1993) 1992 Correspondenceand papersarising from White Paper 1992-1993 Includes letter from N.J. Lane to Clarke seeking her views on women in reply, September 1992. Clarke’s_ science, with Copyof ‘The Rising Tide. A report on Womenin Science, Engineering and Technology’ Spiral bound notebooklabelled ‘PH Clarke OST Women in Science 1993’ Manuscript notes from launch of the report in February 1994. 1994 1993 B.24 Papers on the responseto the report 1994 Includes Technology’, press-releases therefrom. the ‘Women in Science, and official government response, and arising Engineering government measures on B.25-B.28 B.25 B.26 ‘Women in Committee correspondence’ Science D2. The Rising Tide. OST 1993-1994 Chiefly papers of the Committee and its work; press cuttings on the reception of the report. ‘Issues to be addressed’; minutes of meetings of the Committee 1993-1994 Comments on and section of draft report 1993 P.H. Clarke NCUACS 120/6/03 B.27 B.28 Womenin science Newspaper and magazine coverage of the launch of the report Also includes newspapercuttings re the broader issue of women in science. Letter re activities of Cornwall Women in Engineering Science & Technology With enclosures and Clarke’s reply. 19 1994 1994 B.29-B.32 ‘Women in Science E. Royal Society’ 1992-1995 chiefly concerns the Society’s The material celebration of the fiftieth anniversary of admission of the first women to the Fellowship of the Royal Society in 1945. Royal B.29 B.30 B.31 Correspondencere ‘The admission of the first women to the Royal Society of London’ by J. Mason, Notes & ‘Records of the Royal Society, vol 46 (1992) Includesoffprint. Programme for exhibition on ‘Women in Botany: from Drawing Room to Laboratory’ Royal Society meeting on The Rising Tide - the next wave’, Royal Society, London, 19 April 1995 Letter to Clarke re the programme; list of participants; exhbition brochure. 1992 1994 1995 B.32 ‘The womenFellows’ jubilee’ by J. Mason 1995 16pp typescript. B.33-B.35 ‘Women in Science F. Women in Science Newsletter. AWISE [Association and Engineering]’ for Women in Science 1992-1998 P.H. Clarke NCUACS 120/6/03 20 Womenin science B.33 Women and Science newsletters 1992-1994 Issues 1-11. B.34, B.35 Association for Womenin Science and Engineering and related material c 1993-1998 2 folders. B.36-B.38 ‘Women’ 1996-1998, n.d. Contents of Clarke’s folder so inscribed divided into three for ease of reference. B.36 Reports from the Office of Science and Technology’s Development Unit on Womenin Science, Engineering and Technology 1996 B.37 Printed material on women in science and academia 1998 B.38 Miscellaneous typescript and manuscript material n.d. B.39-B.48 Material on women in science found separately 1987-2002 B.39 B.40 Miscellaneous correspondence 1987-1997 Science Policy Support Group Policy Analysis Forum on Women in Science, London, 13 March 1992 1992 Programme; list participants; manuscript notes on proceedings of information; Clarke’s B.41 Correspondence re Dorothy Hodgkin Fellowships 1995, 1999 Clarke served on the Royal Society’s Dorothy Hodgkin Fellowship selection panel B from 1995 to 1999 when she resigned. P.H. Clarke NCUACS 120/6/03 21 Womenin science B.42 Correspondencewith J. Mason and H. Rose 1998 Correspondence re inaccuracies in Rose’s Foreword to Women, Science and Medicine 1500-1700. B.43-B.45 B.43 Royal Society meeting on Womenin Science, Royal Society, London, 27 March 2001 2001 Invitation; programme; information; Clarke’s manuscript notes on proceedings B.44, B.45 Printed background information on schemes to promote women in science 2 folders. B.46 B.47 Information about opportunities for women scientists in the European Molecular Biology Organisation 2002 Newspaper and magazinecuttings The cuttings relate to women in science and opportunities for women in other careers. B.48 Miscellaneous material n.d. P.H. Clarke NCUACS 120/6/03 22 SECTION C PUBLICATIONS AND LECTURES, C.1-C.54 1972-2001 C.1-C.43 PUBLICATIONS C.1, C.2 ‘Introduction: Pseudomonas aeruginosa, an opportunist pathogen’, in Pseudomonas Infection and Alginates: biochemistry, genetics and pathology, eds. P. Gacesa and N.J. Russell (London: Chapman & Hall, 1990). book planned workshop on This Extracellular Pseudomonas aeruginosa, held at Gregynog Hall, University of Wales, 15-17 September 1986. See also E.18. virulence factors a of arose from 1972-2001 1987-1989 1988 Draft of chapter 16pp typescript. C.1 C.2 Correspondencewith editors and publishers 1987-1989 C.3-C.5 ‘Microbesfor the control of pollution’ 1985 144pp typescript. 3 folders. was found This ‘...] Commissioned 1985 by the ILB. Deposited not published. Invited by B.R. Rabin’. envelope inscribed an_ in C.6-C.11 ‘Regulation of Expression of Microbial Genes’, in Further milestones in biochemistry, eds M.G. Ord and L.A. Stocken, Greenwich, Conn. JAI Press, 1997, pp 234-273 1996-1997 C.6 C.7 C.8 45pp typescript draft, May References, tables, figures for preceding draft 46pp copy edited typescript 1996 1997 P.H. Clarke NCUACS120/6/03 C.9 C.10 C.11 Publications and lectures References, tables, figures for copy edited draft Proof copy 23 1997 1997 Correspondenceetc. 1996-1997 C.12-C.14 ‘Muriel Robertson 1883-1973’, New Dictionary of National Biography 1974-1999 C.12 C.13 C.14 Typescript draft 1996 Correspondence with editors and others 1994-1999 Backgroundinformation on Robertson 1974-1997 C.15-C.19 ‘Roger Yate Stanier 1916-1982’, Biographical Memoirs of Fellows of the Royal Society vol 32 (1986) 1983-1986 C.15 C.16 See also F.73. Off-print of the Memoir Correspondencewith friends and colleagues of Stanier 1983 Letters reminiscences of Stanier. Clarke to giving information about and C.17 Background information on Stanier Includes 4pp typescript on Stanier by W.C. Evans C.18 Letters commenting on Clarke’s draft 1983 1985 P.H. Clarke NCUACS 120/6/03 24 Publications and lectures C.19 Letters of appreciation to Clarke C.20-C.31 ‘Malcolm Douglas Lilly 9 August 1939-18 May 1998’, Biographical Memoirs of Fellows of the Royal Society vol 46 (2000) 1998-2001 Lilly undertook postgraduate reseach under Clarke at University College London 1959-1962. He remained at UCL for the rest of his career, being appointed Professor of Biochemical Engineering in 1979. C.20 C.21 C.22 C.23 26pptypescript draft Draft bibliography 30pp typescript. Off-print of Memoir 2000 2000 2000 Correspondence and papers from the Royal Society 1998-2001 Includes invitation to write the memoir and copies of information on Lilly held by the Royal Society, and later correspondence re publication. C.24 Background information 1998-2000 Includes copy of the Guardian obituary of Lilly (18 June 1998), of autobiographical tape-recording; etc. curriculum Lilly's __—vitae;_—s transcript C.25 C.26 Clarke’s typescript and manuscript notes onLilly'slife, the structure of the memoir; sources to be consulted. 1998-1999 Clarke’slists of friends and colleaguesofLilly P.H. Clarke NCUACS 120/6/03 25 Publications and lectures C.27-C.29 Correspondencefrom friends and colleaguesofLilly 1999-2000 to of Lilly. giving Clarke and Letters reminiscences of correspondence are numbered by Clarke in a sequence from 3-44 (not complete). information exchanges Individual about C.27 C.28 C.29 C.30 3-29 31-37 41-44 and others Includes correspondence with Peter Dunnill, originally working as a co-author of the memoir. Correspondence of appreciation from friends and colleagues on completion of the memoir Lillys widow and letters with 1998-2001 C.31 Spiral bound notebook 1998-2001 Labelled on front cover ‘Malcolm Lilly RS Biog Memoir’, used asa diary for work in progress on the memoir. C.32 C.33-C.35 experiment ‘An. with Pseudomonas aeruginosa amidase’, with R.E. Drew, Bioscience Reports vol 8 (1988) in enzyme evolution: studies Correspondencewith editors. Review of: M. Allaby, Facing the future: the case for science Science Progress Bloomsbury, (London: 1995), in This was originally entitled ‘Beyond Doom: the case for science’. Much of the material is correspondence with publishers and M. Allaby re a reference queried by Clarke. 1986-1988 1995 P.H. Clarke NCUACS 120/6/03 26 C.33 C.34 C.35 C.36 Publications and lectures 2pp typescript; 2pp earlier typescript draft annotated ‘Replaced’ Correspondence with Science Progress Correspondence with publishers and author B. Gates, Kindred Nature: Victorian and Review of: Edwardian Women Embracethe Living World (Chicago, 1998), in Notes and Records of the Royal Society 1999 2pp typescript; proof copy. C.37-C.42 Editorial correspondence 1984-1994 Arranged alphabetically by publishing houseor journal. C.37 Chapmanand Hall C.38 Refereeing. Nature Refereeing. C.39 Pergamon Press Requestfor advice. 1988 1990 1988 C.40, C.41 Science Progress 1984-1994 Correspondence and contributors, editorship. papers re_ editorial policy, 2 folders. Clarke served as an editor of this journal, jointly to 1989, then sole editor to 1994. P.H. Clarke NCUACS120/6/03 27 Publications and lectures C.42 Trends in Biotechnology 1990 Refereeing. C.43 Offprints of articles by Clarke 1972-2000 Not a complete set. C.44-C.54 LECTURES 1979-1998 1978-1979 C.44 C.45 C.46 ‘Experiments in microbial evolution: new enzymes, new metabolic Leeuwenhoek Lecture, 8 November 1979 activities’, Royal Society Correspondencere arrangements; notice; abstract. ‘How to evolve a new microbe. A case study in enzyme evolution’, 1982 1982 20pp typescript + tables and figures; manuscriptlist of slides. Manuscript note on front page ‘Originally asked for manuscript for publication but did not follow up’. ‘The scientific foundations of modern biotechnology’, 2nd Encontro Nacional de Biotechnologia, Porto, Portugal, 1984 1984 30pp typescript + figures. Manuscript note on front page ‘Asked for manuscript for publication but did not publish after all’. C.47 ‘Tailoring bacterial enzymes’, International Symposium on Microbiology in the Eighties, Singapore, May 1985 1985 15pp typescript + figures. P.H. Clarke NCUACS120/6/03 Publications and lectures ‘Experiments on the evolution of bacteria with novel enzyme invited lecture at the Karolinska Institute, Stockholm, Sweden, 1985 (Experimental evolution)’, activities 22pp typescript. Education Colleges and Polytechnics. The ‘Further Scope and Implications’, Department of Education and Science Invitation Conference on Biotechnology, Keble College, Oxford, 19-20 March 1986 C.48 C.49 C.50 C.51, C.52 C.51 C.52 C.53 C.54 28 1985 1986 9pp typescript. See also E.17. ‘The ubiquitous pseudomonads’, European Molecular Biology Workshop, Geneva, Switzerland, September 1986 1986 17pp typescript + captionsfor figures. directions ‘New biotechnology’, College London, 12 May 1988 biology: J.D. in 19th and Birkbeck 1987-1988 basic science Bernal Lecture, 29pp typescript draft + notes 1988 Correspondence re arrangements; background material 1987-1988 ‘Protein engineering in vivo’, Anniversary Congress of University Protein Engineering, The Netherlands, 14-18 August 1989 Groningen Prospects on of in Covering abstract; typescript with manuscript corrections; list of slides. 4pp typescript letter with 7pp ‘The Human Genome Project’, Science and Technology Society, 25 February 1998 talk to Cirencester typescript; 13pp transparencies. copies of figures for overhead 1989 1998 P.H. Clarke NCUACS 120/6/03 29 SECTION D SOCIETIES AND ORGANISATIONS, D.1-D.25 1975-2001 D.1-D.7 BRITISH NATIONAL BIBLIOGRAPHICAL RESEARCH FUND D.8 PALM OIL RESEACHINSTITUTE OF MALAYSIA D.9-D.14 RESEARCH GRANTS COUNCIL OF HONG KONG D.15-D.20 ROYAL SOCIETY D.21, D.22 SOCIETY FOR THE PROTECTION OF LEARNING AND SCIENCE D.23 D.24 D.25 UNIVERSITY OF BATH UNIVERSITY OF KARACHI WYE COLLEGE, UNIVERSITY OF LONDON D.1-D.7 BRITISH NATIONAL BIBLIOGRAPHICAL RESEARCH FUND 1975-2001 This Fund was established in 1975 with funds from the British Library following the dissolution of the Council of the British National Bibliography Ltd (1949-1975). It supported bibliographic and related research in the UK. The Fund was taken over by Resource, the Council for Museums, Archives andLibraries, in 2000 and abolished in 2001. Clarke represented the Royal Society on the Fund’s Committee from 1991 and opposedits abolition. D.1-D.3 Minutes of meetings 1990-2001 Also includes at D.1 letter of 18 October 1990 welcoming Clarke to the Committee. Societies and organisations P.H. Clarke NCUACS 120/6/03 D.14 D.2 D.3 Minutes Minutes Minutes 30 1990-1994 1995-1997 1998-2001 D.4-D.7 Correspondence and papers re Committee final years of the 1998-2001 Includes lobbying to try to ensure the survival of the Committee. D.4 D.5 D.6 D.7 D.8 1998-1999 2000 2001 Includes report, for the record, on the work of the Fund written by Clarke for the Royal Society and brief note on her involvement with the Fund. Backgroundinformation 1992, 1998 PALM OIL RESEACH INSTITUTE OF MALAYSIA 1989-1992 Correspondence Subcommittee. and papers re meetings of the Clarke served on the Biology Subcommittee of the Institute’s Programme Advisory Committee 1990-1992. In connection with her membership she made a number of visits to Malaysia, some of which are documented further in section E. P.H. Clarke NCUACS 120/6/03 31 Societies and organisations D.9-D.14 RESEARCH GRANTS COUNCIL OF HONG KONG 1988-2000 Correspondence and papers re assessmentof projects. Clarke evaluated research projects for the Research Grants Council of Hong Kong. Grant proposals 1988, 1991 Workon indigo and sulfur black dye Work on Bacillus subtilis Work on Bacillus subtilis cloning 1993 1993 1998 Work on cultured mycelial products of mushroom species 1999 Work on cultured mushroom mycelia 2000 D.9 D.10 D.12 D.13 D.14 D.15-D.20 ROYAL SOCIETY 1985-1997 The material, which is not extensive, chiefly documents Clarke’s association with the Royal Society’s Library Committee and its Working Group on ArchivesPolicy. Clarke was elected to the Fellowship of the Royal Society in 1976. She was on Council and a Vice-President 1981- 1982 and served on a number of committees including the Library Committee 1980-1990 (Chairman 1983-1990) and its Working Group on Archives Policy (Chairman 1985-1990), the Notes & Records Editorial Advisory Board 1989-1997, the Research Grants Scheme Board 1997-1999, and the Advisory Committee to the National Cataloguing for the Archives of Contemporary Scientists 1987-1997. Unit P.H. Clarke NCUACS 120/6/03 32 Societies and organisations D.15, D.16 Archives Working Group D.15 D.16 Invitation to serve, 1985; report, 1988 Reports D.17-D.19 Library Committee D.17 D.18 D.19 Minutes of Clarke’s last meeting as chairman ‘The Library of the Royal Society’ 12pp typescript annotated ‘1990 for Library Committee’. Correspondence and papers re history of the Royal Society Library Clarke wrote the Foreword to The Library and Archives of the Royal Society by M.B. Hall (London: Royal Society, 1992). 1985-1989 1985, 1988 1988, 1989 1990 1990 1990 1992 D.20 Miscellaneous correspondence 1987-1997 D.21, D.22 SOCIETY FOR THE PROTECTION OF LEARNING AND SCIENCE 1986-1999 Clarke wasinvited to become a member of the Council of Managementof the Society in 1986. She served to 1999. D.21 D.22 Photocopy of invitation to serve, 1986; miscellaneous correspondence 1992-1999 1986-1999 Minutes of meetings 1993-1999 P.H. Clarke NCUACS 120/6/03 33 Societies and organisations D.23 UNIVERSITY OF BATH 1993-1996 Correspondence re Council service. Clarke served on the Council of the University of Bath as a lay member to 1993. D.24 UNIVERSITY OF KARACHI 1991-1993 Acting as external examiner D.25 WYE COLLEGE, UNIVERSITY OF LONDON 1986 Letters re Clarke’s resignation as a University of London representative on the Governing Body of Wye College. P.H. Clarke NCUACS 120/6/03 34 SECTION E VISITS AND CONFERENCES,E.1-E.36 1971-1998 The material includes later accounts prepared by Clarke in or around 1998. E.14 Visit to Australia 1971 c 1998 Clarke’s typescript accounts, based in part on her diary records, of her travels in the USA, New Zealand and Australia. Clarke spent her sabbatical in 1971 working with Bruce Holloway in his laboratory in the Department of Genetics, Monash University, Australia. She travelled via the USA, where she visited colleagues, and also gave some lectures in New Zealand. Clarke’s later typescript accounts of visits to Singapore and Malaysia during the 1970s, 1980s and 1990s Discussion Microbiology, Royal Society, London, 20-21 June 1979 on New Horizons Meeting in_ Industrial Programme; correspondencearising. c 1998 1979 E.2 E.3 Clarke spoke biodegradation compounds’. on of ‘Microbiology and natural and synthetic pollution: the organic E.4-E.6 Joint Royal Society/Science and Engineering Research Council visit to Japan, 14-24 April 1982 1984, 1988 Clarke was one of two Royal Society representatives (with Sir James Baddiley). E.4 Report to the Royal Society E.5, E.6 Clarke’s typescript report on visit 1982 1982 The report gives, firstly her personal accountof the visit and, secondly, her reports on visits to individual science and technologyinstitutions in Japan. 2 folders. P.H. Clarke NCUACS 120/6/03 35 Visits and conferences E.7 Meeting on Pseudomonas Genetics and their Biosurface Phenomenon, Warren Spring Laboratory, Stevenage, Hertfordshire, 14 October 1985 1985 Letter re arrangements, agenda; list of participants. E.8-E.10 4th General Assembly of the International Foundation for Science, Rabat, Morocco, 15-18 October 1984 1984-c 1998 Clarke attended as the official UK delegate on behalf of the Royal Society. E.8, E.9 Papers for the General Assembly 1984 2 folders. 1988 booklet on the participation at the General Assembly, c 1998. IFS; note by Clarke on her 1988, c 1998 E.11-E.16 Visit to Hong Kong and China, January-February 1986 1984-1990 She gave a series Clarke wasinvited to visit the Chinese University of Hong Kong (CUHK) on the Kan Tong Po Visiting Professorship Scheme. of seminars to the Departments of Biology and Biochemistry on work on Pseudomonas aeruginosa and on ‘Evolution of novel catabolic activities in bacteria’. She produced a report for the university on research in biotechnology. Clarke also visited the University of Hong Kong. The Royal Society then suggested Clarke extend her visit into later February and go on to China under the Exchange Scheme with the Academia Sinica. Correspondencere arrangementsto visit Hong Kong 1984-1985 Notices for seminars by Clarke; biographical outline of Clarke. ‘Report on Clarke’s in Biotechnology at the Chinese University of Hong Kong, February; information on the Departmentof Biology at the CUHK. Research Teaching and 1986 E.12 E.13 P.H. Clarke NCUACS 120/6/03 36 Visits and conferences E.14 E.15 E.16 E.17 E.18 Clarke’s ‘Report on visit to China under Exchange Scheme with Academia Sinica’; brochure on Shanghai Institute of Biochemistry. 1986 Correspondence arising from visits to Hong Kong 1986, 1990 Clarke’s later typescript accounts of visits to Hong Kong and China c 1998 of Invitation Department Conference on Biotechnology, Keble College, Oxford, 19- 20 March 1986 Education Science and Programme; list of participants. Clarke spoke on Polytechnics. The Scope and implications’, see C.49. Education Colleges ‘Further and on Workshop of Pseudomonas aeruginosa, Gregynog Hall, University of Wales, 15-17 September 1986 Extracellular virulence factors 1986 1985-1986 Brief correspondence manuscript notes. re arrangements; programme; Clarke chaired the second session on Structural aspects of pathogenity - the organism. She contributed to the planned volume arising from the meeting, see C.1, C.2. E.19, E.20 Sixth Symposium of the Federation of Asian and Oceanic Biochemists, Karachi, Pakistan, October-November 1987 1987-c 1998 Clarke microbial fermentations’. The proceedings were published in 1989. products spoke ‘New on from E.19 E.20 7pp typescript draft of Clarke’s contribution 1987 Correspondence arising; Clarke’s later account of the visit to Pakistan 1987, 1989, c 1998 Clarke’s account was transcribed from notes taken at the time of the visit. P.H. Clarke NCUACS 120/6/03 37 Visits and conferences E.21, E.22 Visit to Malaysia, 22 March-7 April 1988 1988 Clarke visited the University of Malaya as External Examiner in Microbiology for the Department of Genetics and Cellular Biology. She also visited the Palm Oil Research Institute (see D.8) where she spoke on ‘Recent developmentsin Biotechnology in Britain’. Reports on the Department of Genetics and Cellular Biology 1988 Itinerary; 7pp typescript Clarke’s biotechnology; correspondencearising from visit notes for talk on 1988 UK-Japan London, 25-26 April 1988 Biotechnology Workshop, Royal Society, 1988 Programme; bound abstracts, annotated by Clarke. E.21 E.22 E.23 E.24-E.26 Visit to Hong Kong, August 1988 1987-1988 Clarke visited Hong Kong to attend the 8th International Conference on Global Impacts of Applied Microbiology, held with the International Conference on Applied Biology and Biotechnology, Chinese University of Hong Kong, 1-5 August. She spoke on ‘New enzymes from bacteria’. Clarke made other visits in Hong Kong on behalf of the British Council and the Royal Society. Correspondencere arrangements 1987-1988 7pp annotated typescript of Clarke’s contribution; 1p references. Manuscript notes on visit; typescript reports to the British Council and Royal Society Programme Advisory Commitee Seminar on Current Developments in Protein Engineering, Palm Oil Research Institute of Malaysia, 16 March 1990 1988 1990 E.24 E.25 E.26 E.27 P.H. Clarke NCUACS 120/6/03 38 Visits and conferences Programme; abstract; 9pp typescript. E.28 Workshop on Library Provision for the Culture of Science, Technology and Medicine, Royal Society, London, 23 October 1990 1990 List of participants; typescript proceedings. E.29 Royal Society Anniversary Day, 30 November 1990 1990 Letter of invitation; programme; copy of speech proposing a vote of thanks to President of the Royal Society, and 4pp typescript of Clarke’s speech seconding it. E.30 Meeting Science Museum London, 10-11 April 1992 on J.B.S. Haldane: Science and Society, 1992 Programme; list of particpants; abstracts. Clarke was a member of the organising committee. See also E.33-E.35 below. E.31, E.32 Programme Advisory Commitee meeting, Research Institute of Malaysia, 13-18 April 1992 Palm Oil 1992 E.31 E.32 Schedule and programme Report on status of palm oil tissue culture research in relation to abnormalities This was prepared for the meeting. E.33-E.35 J.B.S. Haldane Centenary Meeting, University College London, 6 November 1992 1992 Clarke spoke on ‘Haldane and Biochemistry: enzymes andtheorigin oflife’. See also E.30 above. P.H. Clarke NCUACS 120/6/03 39 E.33 E.34 E.35 Visits and conferences typescript 7pp transparencies of Clarke’s lecture; figures for Also includes covering letter sent with abstract. Abstracts of contributions Backgroundinformation on Haldane Includes Clarke’s manuscript notes, photocopies and printed material. E.36 Invitations declined 1985-1994 P.H. Clarke NCUACS 120/6/03 40 SECTION F CORRESPONDENCE,F.1-F.78 1963-2001 The bulk of this material was arranged by Clarke in envelopes organised by group of correspondents. It has beenretainedin this original order. the envelopes are Many of further subdivided by correspondent, sometimes with a later note by Clarke explaining her relationship with the correspondent. At F.74-F.78is a little correspondence found loose. F.1-F.7 ‘Bruce Holloway’ 1963-2001 chiefly reporting on Correspondence Pseudomonas aeruginosa and related research but also including family, personal andsocial newsof colleagues arrangements for visits and with on work F.1 F.2 F.3 Bruce Holloway was an Australian colleague of Clarke’s who made his career at Monash University, Victoria. Their association through research on P. aeruginosa spanned some four decades and is described in Clarke’s note of 2001 at F.1. Note by Clarke on B.W. Holloway, 2001; curriculum vitae 1970 1970, 2001 1963-1967 Correspondence re Pseudomonasgenetics 1969-1975 Work on P. aeruginosa strains; contribution to Genetics and Biochemistry of Pseudomonas, eds. Clarke and M.H. Richmond (London: Wiley, 1975); visits to UK. F.4 1976-1981 Chiefly genetic linkage mapping of Pseuodmonas. P.H. Clarke NCUACS 120/6/03 F.5 F.6 F.7 Correspondence 1982-1985 Visits and social news; P. aeruginosa gene mapping 1982, 1985 Career. 1988-1998 Chiefly personal and social news. F.8-F.11 ‘PseudomonasGroup Rob Drew’ 1989-1998 Chiefly correspondence re work in progress, including drafts of work sent to Clarke for comment. research Chiefly Pseudomonas aeruginosa, though later correspondence includes social and personal news. genetics on_ of Robert E. Drew wasa colleague of Clarke’s based at the University College London Department of Biochemistry and Molecular Biology. F.8 1989-1990 Includes typescript draft of ‘Cloning, DNA sequence and purification of amicC, a new gene regulating expression of the Pseudomonas aliphtic amidase’ by Drew and S.Wilson, sent to Clarke for comment. F.9 1991-1992 typescript Includes of amidase expresion in Pseudomonas aeruginosa’ by Drew and S. Wilson, sent to Clarke for comment, c 1992. ‘Regulation draft of F.10 1993, 1995 Includes copy of presentation on ‘The P. aeruginosa transcriptioin antiterminator AmiR, binds to the Leader mRNAin the amidase operan’ by Drewetal. P.H. Clarke NCUACS 120/6/03 42 Correspondence F.11 1996-c 2000 Includes copy of presentation on ‘Antitermination of amidase expression in Pseudomonas aeruginosa is controlled by a novel cytoplasmic amide-binding protein’ by Drewet al. F.12-F.26 ‘UCL Research Group Students etc’ 1975-1996 Correspondence with former University College research students, laboratory workers and visiting researchers. Some have a note by Clarke giving some biographical information. Arranged in alphabetical order by surname. F.12 Betz, J.L. 1985-1994 Betz was a Ph.D. student of Clarke’s. F.13 Daly, G. 1975 Greta Daly was a technician who studied for her B.Sc. in biochemistry before moving to Australia. F.14 Day, M.J. 1974-1995 Includes correspondencere career. Day was a research student of Clarke’s who spent much of his career at the University of Wales, Cardiff. F.15 Draper, P. With typescript note by Clarke. F.16 Finer, N. Oneletter only. Finer was an ex-technician of Clarke’s. 1984 1984 P.H. Clarke NCUACS 120/6/03 43 Correspondence F.17 Karunakaran, V. 1990 Oneletter only, re career. F.18 Keshavaraz, T. 1985-2001 Chiefly re career. With typescript note by Clarke. Clarke and M.D. Lilly supervised Keshavaraz’s Ph.D. in biochemical engineering at University College London. F.19 Laverack, P.D. 1989, 1990 Laverack was a former technician in Clarke’s laboratory. F.20 Meadow,P.M. 1987, 1991 Twoletters only. Pauline Meadow (married name Enticknap) held a Beit Fellowship for research with Clarke at UCL 1956-1957. They developed a research group and when her Fellowship ended she was appointed Lecturer. Meadow later became Reader in Biochemistry and Sub-dean of the Medical Faculty. F.21, F.22 Rice, P.M. and C.M. 1976-1994 Peter and Catherine Clarke’s. Rice were Ph.D. students of F.21 F.22 1976-1979 1980-1994 Chiefly re career. F.23, F.24 Sambanthamurthi, R. 1982-1996 Sambanthamurthi was a Malaysian research student of Clarke’s 1979-1983. P.H. Clarke NCUACS 120/6/03 44 Correspondence F.23 1982-1986 Correspondence re studies and career. personal news. Also includes F.24 1988-1996 Chiefly personal and career news. F.25 Sangodcar,U. 1986, 2002 Oneletter only, 1986, with later typescript note by Clarke. F.26 Trewavas, A. Oneletter only. 1999 F.27-F.32 ‘UCL Misc’ 1982-1998 Correspondence colleagues. Arranged in alphabetical order by surname. University with College London F.27 Armitage,J.P. 1995-1998 Correspondenceand papers chiefly re career. Armitage was a student on the UCL B.Sc. Microbiology course. After graduation in 1972 she went on to Ph.D. research. She remained at UCL to 1985 when she moved to Oxford. She was appointed Professor of Biochemistry at the University of Oxford in 1996. F.28 Banks, B. Career. 1990 Barbara Banks joined the UCL Biochemistry M.Sc. course in 1957. She did a Ph.D. in the Chemistry Department and then joined the Physiology Department. P.H. Clarke NCUACS 120/6/03 Correspondence F.29 Bawden, L.-A. Oneletter only, with reminiscences. F.30 Lighthill, M.J. Obituaries of Lighthill, including appreciation by Clarke, Guardian, 25 July 1998; letter of condolence to Lady Lighthill. The mathematician, Sir James Lighthill, was Provost of UCL. He gave strong support to science and technology andto the position of women in the College. F.34 F.32 Man, D. Robson, E.B. Oneletter only. 45 1999 1998 1981-1985 1984 Bette Robson was Head of the UCL Department of Genetics and Biometry. F.33-F.56 ‘Correspondencewith scientists etc UK’ 1968-1999 Correspondence with British scientists and colleagues. Arrangedin alphabetical order. F.33 Ambler, R.P. 1972-2000 amino acid Correspondence re Clarke and Ambler’s ‘collaboration on the of Pseudomonas aeruginosa’ Also includes exchange re commemoration meeting for M.R. Pollock, 2000. sequence amidase of the Ambler worked in the Edinburgh University Department of Molecular Biology. F.34 Auffret, A.D. 1988 Exchange re work on amidase. P.H. Clarke NCUACS 120/6/03 Correspondence Auffret worked with R.P. Ambler at Edinburgh on the amidase sequence. F.35 Billing, E. Strains of Erwinia. F.36 Brenner, S. Strains of Pseuodmonas aeruginosa. 46 1978 1968 F.37 Buchanan, B.J. 1997, 1998 Correspondence re Waltham Abbey connection. F.38 Buchanan, R.A. 1995-1998 Correspondencere history of science and personal news. F.39-F.44 Cambridge Biochemistry Department 1976-1999 Correspondence with colleagues associated with the Department of Biochemistry at Cambridge. A typescript correspondents and explains her relationship with them. Clarke (F.39) lists the note by F.39 F.40 Bacon, J.S.D. Corran, H.S. 1982 1992-1999 Chiefly personal news and newsofcolleagues. Includes 3pp typescript of Corran’s obituary of their mutual friend R.L.M. Synge, 1994. F.41 Elsden, S.R. 1976-1981 Includes correspondencere Stickland-type reaction. P.H. Clarke NCUACS 120/6/03 Correspondence F.42 Gale, E.F. 1991-1995 F.43 F.44 F.45 F.46 F.47 F.48 Chiefly personal news. Harris, H. Heyningen, R. van Personal correspondence. Davies, M. Dawes, E.A. Exchange re 100th volume of the Journal of General Microbiology. Derewendaa, Z. Howe, T.G.B. Correspondence re Pseudomonasaeruginosastrains. 1995 1996-1997 1982 1976 1989 1974 F.49 Knowles, C.J. 1976, 1984 Includes copy of typescript paper ‘The effect of cyclic AMP onrespiratory activity in Escherichia coli K-12’, sent to Clarke for commentafter its rejection for publication, 1976. F.50 Kornberg, H.L. 1963 One letter only from Kornberg re propionate and growth in Pseudomonasaeruginosa. P.H. Clarke NCUACS120/6/03 Correspondence F.51 Simon, B. Personal news; history of Cirencester schools. Simon was Professor of Education at the University of Leicester. F.52 Slater, J.H. Includes typescript of ‘Environmentally directed mutations in the dehalogenase system of Pseuodmonasputida’ by Slater et al, sent to Clarke for comment. Slater was Professor of Applied Microbiology at the University of Wales. F.53 Smith, W. F.54 F.55 One letter only. Spratt, B.G. Weightman, A.J. Travel grant. F.56 Wright, L.F. Correspondence and papers re work on Pseudomonas aeruginosa. F.57-F.59 ‘Europe’ F.57, F.58 Stalon, V. Victor Stalon worked in the microbiology unit of the Science Faculty of the Université Libre de Bruxelles, Belgium. 48 1992, 1994, 2002 1981-1991 1985 1991 1991 1977 1978-1988 1978-1985 P.H. Clarke NCUACS 120/6/03 49 Correspondence F.57 1978-1979 Correspondence re arginine metabolism. F.58 1983-1985 utilization by Includes draft typescript Pseudomonas species’ by Stalon and A. Mercenier sent to Clarke for comment, 1983, and further correspondence on arginine pathways, 1984-1985. ‘L-arginine of F.59 Miscellaneous correspondents F.60-F.73 ‘Correspondencewith scientists US’ 1968-1997 Correspondencewith US scientists and other colleagues. Arranged in alphabetical order. F.60 Dykhuizen, D.E. 1985 Letter, with enclosures, re mutation in Escherichia coli F.61 Gunsalus, I.C. 1969-1981 Correspondence re Pseudomonas aeruginosa, personal news. Includes typescript biographical note on Gunsalus by Clarke. F.62 F.63 Knowles, J.R. 1976, 1985 Kustu, S. 1980 Oneletter only re work on nitrogen control. P.H. Clarke NCUACS 120/6/03 Correspondence F.64 Lin, E.C.C. Oneletter only, of good wishes onretirement. F.65 Miller, S.L. One letter only, with enclosures. F.66 Olsen, R. 50 1984 1985 1980 Correspondence re visit by Clarke to Michigan. University of Clarke lectured to the Division of Biological Sciences course on Mechanisms of Evolution on ‘Experimental evolution of biochemical pathways’ on 4 November 1980. Molecular F.67 Ornston, L.N. Chiefly correspondence re Ornston’s contribution to Genetics and Biochemistry of Pseudomonas,eds. Clarke and M.H. Richmond (London: Wiley, 1975). F.68 Palleroni, N.J. Correspondence re Palleroni’s contribution to Genetics and Biochemistry of Pseudomonas,eds. Clarke and M.H. Richmond (London: Wiley, 1975). F.69 Phibbs, P. Exchange re proposal to establish a Pseudomonasstock culture collection at East Carolina University. F.70 F.71 Reiner, A.M. Sager, R.D. Chiefly correspondence re visits by Sager and A.B. Pardee to the UK and personal news. 1972-1973, 1985 1973 1991 1977 1980-1997 P.H. Clarke NCUACS 120/6/03 51 Correspondence Ruth Sager wasa distinguished cancer geneticist. She was one of the first women to be elected to the US National Academy of Sciences and the American Academyof Arts and Sciences. F.72 Shooter, E. 1986-1997 Personal news. F.73 Stanier, R.Y. 1968-1969 Correspondence Pseudomonas. Clarke on Stanier’s influence on her work. of Also includes brief typescript note by properties strains re_ of Clarke wrote the Royal Society Biographical Memoir of Stanier, see C.15-C.19. F.74-F.78 Miscellaneous correspondencefound loose 1983-2000 In chronological order. 1983, 1985, 1988 1986 1994 F.74 F.75 F.76 Exchange with Society Biographical Memoir of the biochemist W.C. Evans (1911-1988). J.R. Quayle re Royal his F.77 1991 F.78 2000 52 P.H. Clarke NCUACS 120/6/03 INDEX OF CORRESPONDENTS ALLABY,Michael AMBLER, Richard P. ARMITAGE, Judith Patricia ASSOCIATION FOR WOMENIN SCIENCE AND ENGINEERING AUFFRET,A.D. BACON, John Stanley Durrant BAKER, L.M. BANKS,Barbara BAWDEN, Liz-Anne BETZ, Joan L BILLING, Eve BIOCHEMICAL SOCIETY BIOSCIENCE REPORTS BLACKSTONE, Tessa Ann Vosper, Baroness BRENNER, Sydney C.35 F.33 F.27 B.33-B.35 F.34 F.39 B.39 F.28 F.29 F.12 F.35 A.5 C.32 C.52 F.36 BRITISH NATIONAL BIBLIOGRAPHICAL RESEARCH FUND D.1-D.7 BUCHANAN, Brenda J. BUCHANAN, Robert Angus BUD, Robert F. CHAPMANAND HALL, PUBLISHERS CHINESE UNIVERSITY OF HONG KONG CORRAN, HenryStanley DALY, Greta DATTA, Prakash DAVIES, Martin F.37 F.38 A.19 C.37 E.15 F.40 F.13 A.18 F.45 P.H. Clarke NCUACS 120/6/03 53 Index of correspondents DAWES,Eddie A. DAWKINS, (Clinton) Richard DAY,Martin John DEER PARK SCHOOL CIRENCESTER DEREWENDA,Zygmunt DODSON, George Guy DRAPER, Philip DREW, Robert E. DUNNILL, Peter DYKHUIZEN, Daniel E. ELSDEN, Sidney Reuben FINER, N. GALE, Ernest Frederick GUEST, John Rodney GUNSALUS, Irwin Clyde HAINES, Catharine M.C. HALL, Marie Boas HARDER, Wim HARRIS, Harry HEYNINGEN, Ruth van HOLLOWAY,Bruce William HOWE, T. Gilbert B. JAGER, Karl-Erich KARUNAKARAN, Velautham F.46 A.27 F.14 A.26-A.29 F.47 F.8, F.47 F.15 F.8-F.11 A.18 F.60 F.41 F.16 F.42 A.18 F.61 A.10 D.20 F.59 F.43 F.44 F.1-F.7 F.48 F.59 F.17 P.H. Clarke NCUACS 120/6/03 KESHAVARAZ,Tajilli KNOWLES, Christopher J. KNOWLES,Jeremy Randall KORNBERG, Sir Hans Leo KUSTU, S. LANE, NancyJ. LAVERACK,P.D. LEVERHULME TRUST LIGHTHILL, Sir (Michael) James Index of correspondents F.18 F.49 F.62 F.50 F.63 B.21 F.19 A.13 F.30 LILLY, Malcolm Douglas C.20-C.31 McCRUM, N.G. MAN, Donald MASON, Joan MEADOW, Pauline M. MELLANBY,Jane H. MILLER, Stanley Lloyd MITRA, Asoke N. NATURE NEW DICTIONARY OF NATIONAL BIOGRAPHY OLSEN, Ron ORNSTON, L.N. PALLERONI, NorbertoJ. PALM OIL RESEACH INSTITUTE OF MALAYSIA PERGAMON PRESS PHIBBS, Paul V. B.7 F.31 B.9, B.29, B.39, B.42 F.20 B.39 F.65 A.18 C.38 C.13 F.66 F.67 F.68 D.8 See also E.27, E.31, E.32 C.39 F.69 P.H. Clarke NCUACS 120/6/03 POWELL, Michael QUAYLE, John Rodney RAHMANN, M. Ataur REINER, A.M. Index of correspondents A.18 F.76 E.20 F.70 RESEARCH GRANTS COUNCIL OF HONG KONG D.9-D.14 RICE, Catherine M. RICE, Peter Martin ROBERTS, Sir Derek Harry ROBERTSON, Muriel ROBSON, E. Bette ROSE, Hilary ROYAL SOCIETY SAGER, Ruth Deborah SAMBANTHAMURTHI, Ravigadevi SANGODCAR, U. SCIENCE PROGRESS SHOOTER, Eric SIMON, Brian SLATER, J. Howard SMITH, John Maynard SOCIETY FOR THE PROTECTION OF LEARNING AND SCIENCE SPRATT, Brian G. STALON, Victor STANIER, Roger Yate F.22 F.21, F.22 B.9 See C.12-C.14 F.32 B.42 B.31, C.23, D.6, D.15-D.20, E.15, E.29 F.71 F.23, F.24 F.25 C.34, C.35, C.40, C.41 F.72 F.51 F.52 A.18 D.21, D.22 F.54 F.57, F.58 F.73 See also C.15-C.19 P.H. Clarke NCUACS120/6/03 Index of correspondents TEMPEST,David W. TRENDSIN BIOTECHNOLOGY TREWAVAS, Anthony James UNIVERSITY OF BATH UNIVERSITY OF KARACHI UNIVERSITY OF MALAYA WARNER, Sir Frederick Edward WEIGHTMAN, Andrew John WRIGHT,L. Fred WYE COLLEGE, UNIVERSITY OF LONDON ZAHRINGER, Ulrich F.59 C.42 F.26 D.23 D.24 E.22 A.19 F.55 F.56 D.25 F.59