LILLY, Malcolm Douglas v2

LILLY_MALCOLM_DOUGLAS_v2

Catalogue of the papers and correspondenceof Malcolm Douglas Lilly FEng FRS (1936-1998) By Peter Harper and Timothy E. Powell NCUACScatalogue no.150/7/06 M.D.Lilly NCUACS 150/7/06 1 Title: Catalogue of the papers and correspondenceof Malcolm DouglasLilly (1936- 1998) FEng FRS, biochemical engineer Compiled by: Peter Harper and Timothy E. Powell Date of material: 1957-2003 Extent of material: ca 2,000 items Depositedin: Special Collections, Library, University College London Reference code: GB 0103 M.D.Lilly © 2006 National Cataloguing Unit for the Archives of Contemporary Scientists, University of Bath NCUACScatalogue no. 150/7/06 M.D.Lilly NCUACS150/7/06 NOT ALL THE MATERIALIN THIS COLLECTION MAY YET BE AVAILABLE FOR CONSULTATION. ENQUIRIES SHOULD BE ADDRESSED IN THE FIRST INSTANCE TO: HEAD OF SPECIAL COLLECTIONDS AND ARCHIVIST SPECIAL COLLECTIONS LIBRARY SERVICES UNIVERSITY COLLEGE LONDON M.D.Lilly NCUACS150/7/06 The workof the National Cataloguing Unit for the Archives of Contemporary Scientistsin the production of this catalogue is made possible by the support of the following societies and organisations: Biochemical Society Institute of Physics Royal Society Royal Society of Chemistry Trinity College Cambridge University College London Wellcome Trust M.D.Lilly NCUACS150/7/06 LIST OF CONTENTS GENERAL INTRODUCTION Items Page SECTION A BIOGRAPHICAL A.1-A.15 SECTION B NOTEBOOKS AND RESEARCH NOTES B.1-B.46 SECTION C UNIVERSITY COLLEGE LONDON C.1-C.971 SECTION D PUBLICATIONS SECTION E LECTURES D.1-D.366 E.1-E.69 SECTION F SOCIETIES AND ORGANISATIONS F.1-F.372 SECTION G CONSULTANCIES G.1-G.157 SECTION H VISITS AND CONFERENCES H.1-H.76 SECTION J CORRESPONDENCE J.1-J.22 INDEX OF CORRESPONDENTS 10 12 18 76 117 123 156 166 177 180 M.D.Lilly NCUACS150/7/06 GENERAL INTRODUCTION PROVENANCE 5 The papers werereceived from Mrs Sheila Lilly, widow, in June 2004 and September 2005. OUTLINE OF THE CAREER OF MALCOLM DOUGLASLILLY Malcolm DouglasLilly was born on 9 August 1936. He grew up in Eltham in South London and was educated at St Olave’s and St Saviour’s Grammar Schooland, after a period of national service in the Royal Navy, University College London where he read biochemistry and went on to research on microbial enzymes in the research group of the Patricia H. Clarke, working with Pauline Meadow (PhD 1962). Lilly then transferred to the Department of Chemical Engineering to work on immobilised enzymes with Eric Crook (NCUACS catalogue 147/4/06). In 1963 he was appointed Lecturer in Biochemical Engineering, joined a few years later by. Peter Dunnill wno became his closest collaborator. One of the key areas of their research ‘was the development of methodsfor using the high specificity of enzymes for complex reactions that were difficult to carry out by standard chemical methods. Because biological molecules, such as enzymes, are not as stable as industrial chemicals, basic research was needed to find out the best methods for maintaining their structure, and catalytic properties during purification and large-scale operations. It was also essential to develop appropriate equipment. ... [They] investigated equipment already used in industry. For example, they found that milk homogenisers used by the dairy industry could be used for disrupting micro-organisms. Later they improved the design of the fermenters in which the micro-organisms were grown. Malcolm’s early work on the properties of enzymes immobilised by attachment to resin beads had particular importance. Immobilised enzymes have increased stability and can be used in commercial bioreactors for longer periods. One of the early successes at UCL was using an immobilised bacterial enzyme for the production of semi-synthetic penicillins. He researched biotransformation throughout his career, but also worked on other topics including mammalian cell culture, nucleotide isolation and biological fuel cells’. Obituary by Patricia H. Clarke, Guardian, 18 June 1998. Lilly’s career was closely connected to the developmentof biochemical engineering at UCL. In 1964 a Biochemical Engineering Section was established within the Department of Chemical Engineering and in 1966 the University of London approved the establishment of an MSc, with an undergraduate degree following in 1973. In 1979 Lilly was appointed the first Professor of Biochemical Engineering in the country. Further recognition for biochemical engineering at UCL came with its recognition as a national centre by the Science and Engineering Research Council (SERC) in 1987, the start of the M.D. Lilly NCUACS 150/7/06 6 construction of an Advanced Centre for Biochemical Engineering in 1990 and in 1991 the establishment there of the UK Interdisciplinary Research Centre (IRC) in Biochemical Engineering supported by the SERC. Peter Dunnill was Director and Lilly, Chairman. The final step in a long struggle for the academic recognition was achieved in 1998 with the establishment of a separate Departmentof Biochemical Engineering as part of the School of Process Engineering. Outside UCL Lilly was active in supporting biochemical engineering nationally and internationally. In 1981 when the Science and Engineering Research Council set up a Biotechnology Directorate under Dr Geoffrey Potter to encourage research in the field, Lilly (and others from UCL) served on the Biotechnology Management Committee. He was involved in several newinternational organisations including the International Organisation for Biotechnology and Bioengineering (Chairman 1972-1980) and the European Federation of Biotechnology. With colleagues from the Polytechnic of Central London (now University of Westminster) and the University of Kent he set up the Institute for Biotechnology Studies (later International Institute of Biotechnology), to promote multidisciplinary developments in biotechnology research and teaching. He was a member of the Board of Management and Executive Committee, 1983-1989. Other public responsibilities that he undertook included membership of the Research Board of British Gas, 1982-1994 and membership of the Board of the Public Health Laboratory Service, 1988-1994. His outstanding achievement in biochemical engineering was widely recognised. In 1976 he was awarded the Food, Pharmaceutical and Bioengineering Award of the American Institute of Chemical Engineering, the first non-American to receive the award. He was elected to the Fellowship of Engineering (now Royal Academy of Engineering) in 1982 and of the Royal Society in 1991, the first biochemical engineer to receive both awards. He was a visiting Professor at the University of Pennsylvania in 1969 and a Visiting Research Fellow at Merck, USAin 1987. In 1959 he married Sheila Stuart with whom he had two sons. At the height of his powers he was struck by cancer, which he fought courageously for more than ten years. With the support of his wife he wasable to continue research until the last days of his life. He died on 18 May 1998. For further information on the life and work of Lilly see ‘Malcolm DouglasLilly 9 August 1936 - 18 May 1998’ by Patricia H. Clarke, Biographical Memoirs of Fellows of the Royal Society, vol.46, pp 317-332 (2000). M.D.Lilly NCUACS150/7/06 7 DESCRIPTION OF THE COLLECTION The collection is presented as given in the list of contents. It is dominated by extensive documentation of the development of biochemical engineering at University College London and covers the period 1957-2003. Section A, Biographical, is slight but includes a copy of the obituary that appeared in the Guardian newspaper, curriculum vitae, bibliography, list of theses supervised and an interesting record of his lengthy efforts to secure membership ofthe Institution of Chemical Engineers. Section B, Notebooks and research notes, includes a sequence of notebooks covering an extended period, 1962-1998, in a variety of formats and used for a variety of purposes, including address book, lists of things to do, notes of meetings with UCL colleagues, European Federation of Biotechnology meetings, bibliographical references, etc. A notebook used from ‘11/10/1997’is identified as ‘MDL’s last notebook’. In addition there are research notes covering the period, 1965-1997. Some identifiable groups of notes havetitles such as ‘Control Systems’, ‘Fermentation’ and ‘Progesterone Conversion’ but many notes were found loose and in no order and are undated. Section C, University College London, is by far the largest componentof the archive. It documents key aspects of the developmentof biochemical engineering there and covers the period, 1957-2002. It is subdivided into seven subsections: ‘History’, Advanced Centre for Biochemical Engineering (ACBE), Interdisciplinary Research Centre (IRC), Research grants, Teaching and training, Personnel and Miscellaneous. The ‘History’ subsection comprises the contents of folders and box folders labelled ‘history’ or ‘historical’ and includes strategic papers and records of developmentsin teaching, research and facilities. The ACBE subsection includes correspondence and papers relating to the creation of purpose-designedfacilities for training and research activities in biochemical engineering at UCL in an ‘Advanced Centre’, 1986-1995. The IRC subsection documents developments associated with UCL becoming in 1991 the research council funded IRC for Biochemical Engineering with a ten year remit to develop an interdisciplinary programme of research and teaching. There is some overlap with material in ‘ACBE’ files. The Research grants subsection presents correspondence and papers about funding of research and related matters in biochemical engineering at UCL byLilly and colleagues. The material is further organised by funding body or programme, by research contract client and by research topic and under the heading ‘Patents’. The Teaching and training subsection presents Lilly’s ‘teaching notes’ covering a variety of courses for UCL students and others and substantial documentation for biochemical engineering summercourses given at UCL for participants from industry and academe, many from overseas. The dating of the ‘teaching notes’ is often problematic. The summercoursesare fully documented from no.3 to no.15, 1979-1991. The Personnel subsection relates principally to research students and visitors to the Department and M.D.Lilly NCUACS150/7/06 8 documents arrangementsto visit, research, publications and later contacts with the Department. The contents of the Miscellaneous subsection is very diverse including equipment and facilities, research programmes,joint project with Biotechnology Computer Systems Ltd, collaboration with Tel Aviv University and correspondence with UCL Provost, Sir JamesLighthill. Section D, Publications, presents a near comprehensive record ofLilly’s own scientific papers, 1962- 2003, including a number of posthumouspublications. The documentation may include manuscript and typescript drafts, correspondence andoffprints. Also included here are the contents of a folder of ‘unpublished’ drafts. Publications correspondenceis not extensive but there is some material relating to the journals with which Lilly was associated as author, reviewer and editor. Section E, Lectures, provides documentation of Lilly's public and invitation lectures, 1966-1996. Topics include ‘Immobilised Enzyme Reactors’, ‘Developments in Biocatalysis’, "Two-liquid phase biocatalytic reactors’, ‘Industrial Use of Biocatalysts for Asymmetric Synthesis’ and ‘Biochemical Engineering - Its Contribution to Society’, Lilly’s 1988 Sir Harold Hartley Memorial Lecture. There are also many untitled lecture notes and drafts and some illustrative material for lectures and papers. Section F, Societies and organisations, documents Lilly's association with twenty-four British and international organisations, 1968-1998. Amongst the best documented are the European Commission, whose programmes supported biochemical engineering developments at the European level, and the European Federation of Biotechnology (EFB) and the International Organisation for Biotechnology and Bioengineering (IOBB), both of which Lilly served in a number of capacities including for the IOBB a period as chairman. Lilly’s papers include a ‘Formation of the EFB’file. The most comprehensively documented body is the Institute for Biotechnology Studies / International Institute of Biotechnology, including correspondence and papers relating to the formation of the Institute, trustees and management committee meetings, research programme, policy review,etc. Section G, Consultancies, documents consultancy relationships with twenty-one commercial organisations, 1968-1997, including Beckman Instruments Inc, Beecham Group Ltd / Smith Kline Beecham and Merck Sharp & Dohme Research Laboratories. On occasions Lilly consulted in partnership with his UCL colleague Peter Dunnill as Biotech Consultants. Section H, Visits and conferences, covers the period 1964-1998. At the end of the chronological sequenceare papers relating to a number of meetings that Lilly was unable to attend because ofill health. The documentation may include programmes,lists of participants, abstracts and Lilly’s notes on proceedings. M.D.Lilly NCUACS150/7/06 9 Section J, Correspondence, is slight. There is a sequence of correspondence presented chronologically, 1966-1998, made up of letters found loose and without context. There are also references and recommendations, 1968-1998. There is also an index of correspondents. ACKNOWLEDGEMENTS Weare very grateful to Mrs Sheila Lilly for making the papers available for cataloguing and to Mrs Lilly and Professor John Woodleyfor information and advice. LOCATION OF OTHER MATERIAL Correspondence and papersrelating to the preparation of the Royal Society biographical memoir of Lilly form part of the archive of Professor Patricia Clarke catalogued for University College London Library Special Collections (NCUACScatalogue no. 120/6/03). M.D. Lilly NCUACS 150/7/06 10 SECTION A BIOGRAPHICAL,A.1-A.15 1962-2000 A.14 Announcementof death from UCL website 1998 Obituary, Guardian, 18 June 1998 A.2 Curriculum vitae October 1990 Bibliography of 236 publications 1962-2000 2000 List of theses supervised byLilly 1966-1994 A.3 ‘Excited by enzymes’ Short account by Lilly of his research in SERC bulletin, Spring 1994 1994 1962 1968 Extracellular ‘Accumulation Lipoproteins by Lysine Dependent Mutants of Escherichia Col? Nucleotides and_ of Title page only ofLilly’s PhD thesis, April 1962 Nomination papersfor Lilly's candidature for New Scientist Award for outstanding achievement in of technology field the A.4 A.5 A.6 Food, American Institute of Chemical Engineers Pharmaceutical and Bioengineering Award, 1976 Manuscript notesforLilly’s acceptance speech. A.7-A.9 Institution of Chemical Engineers membership, 1979 1964-1980 Correspondence and papersre efforts of Lilly to secure membershipofthe Institution. His definitive election as a Memberofthe Institution was only confirmed in 1979, the year of his election to a personal chair at UCL. He wastransferred to the class of M.D.Lilly NCUACS150/7/06 11 Biographical, A.1-A.15 A.7 A.8 A.Q Fellow in 1980. 1964-1977 1978-1980 N.d. Includes ‘Biochemical Engineering Aspects of Enzyme Technology. A synopsis of research by M.D. Lilly submitted to the Institution of Chemical Engineers’. A.10 Election to Fellowship of the Royal Society 1991 Typescript draft of remarks by Lilly at a gathering of friends and colleagues to markhis election. A.11 Typescript notes etc for Wellcome Trust Witness Seminar on to Resistance’, 12 May 1998 ‘Post-penicillin Antibiotics: From Acceptance Lilly was unable to attend and died on 18 May 1998. A.12 Portrait photograph ofLilly A.13-A.15 ‘Knowledge Acquisition and Implementation of a Prototype for an Expert System to Design Biochemical Reactors’ M.Sc Project by J.T. Sinclair. of the project and is the ‘expert’ referred to in the text. Lilly was interviewed as part Twofolders and bound volume. At A.13 is a letter of thanks from Sinclair to Lilly. 1998 1991 1986 M.D.Lilly NCUACS150/7/06 12 SECTION B NOTEBOOKS AND RESEARCHNOTES,B.1-B.46 1962-1998 B.1-B.34 NOTEBOOKS B.35-B.46 RESEARCH NOTES B.1-B.34 NOTEBOOKS 1962-1998, n.d. These notebooks are in a great variety of formats and serve a numberof purposes. The catalogue entries incorporate identifications by Mrs Sheila Lilly. B.1 Hardback notebook used for ‘Senior / Chief Technician’s notes by Paddy Legge’ 1962-1963 Notes are dated, 31 December 1962 - 6 December 1963. An undated note from ‘Paddy’ to ‘DrLilly’ is enclosed at the front of the notebook. B.2 ‘Research Notes Penicillin amidase’ 1964-1966 B.3 B.4 Hardback notebook so labelled on front cover used for experimental record, ‘19th May’ [1964] - ‘29/10/66’. Some undated notes towards the end of the notebook. The project is outlined in a note inside front cover. Notebook used for ‘MDL’sfirst list of papers ... / a word game/ ref. for Bill Hornby/ ... ‘and ‘Russian when we went to classes in Gravesend 1963 onwards’ Latest bibliographical reference 1965. Small format softback notebook used for research notes, notes headed ‘Flowering Shrubs’, etc. ‘Flowering shrubs were being boughtfor our first home at Northfleet / Gravesend [Kent] in 1964’. N.d. N.d. M.D.Lilly NCUACS150/7/06 B.5 B.6 B.7 B.8 B.9 Notebooks and research notes, B.1-B.46 Small format notebook, very mixed in content, used for notes and chapter headings of book with ?Peter Dunnill, research notes including, from the back, work with P.H. Clarke, etc. Latest bibliographical reference 1966. 13 N.d. Small format hardback notebook usedforlists of things to do 1970-1971 Entries run from 2 June 1970. Small format hardback notebook used from the front for list of publications and from the back forlists of things to do, also notes of Society of Chemical Industry meeting, etc. 1972-1973 Small format hardback notebook used for notes of meetings,etc. N.d. MrsLilly identified the meeting at Rouen with which the notebook begins as dating from 1972. See E.4. Small format notebook usedforlists of things to do and at the backfor list of publications. 1974-1975 Entries run from ‘2.1.74’. B.10-B.14 Five same format softback exercise books used for notes re work of research students 1977-1979 Notebooks have labels on front covers identifying the research students though in the case of B.14 the name has been crossed out. The label for B.10 also identifies the topic ‘Cholesterol Oxidase’. B.15 Hardback notebook usedbyLilly for record of ? incoming correspondenceand action taken 1980 Usedforfirst half of the year only. M.D.Lilly NCUACS150/7/06 Notebooks and research notes, B.1-B.46 format Small publications at front and miscellaneous notes at back hardback notebook used for list B.16 B.17 B.18 B.19 B.20 B.21 B.22 B.23 B.24 14 of ?early 1980s Probably in use early 1980s. Reference to Banff [Alberta, Canada] maybe to 1981 meeting there. See H.23-H.25. Small format hardback notebook used for record of meetings relating for Biotechnology Studies to ?The Institute 1982-1983 See also F.166-F.271. Small format hardback notebookusedforlists of things to do, etc. 1983-1985 Notebook (covers missing) used for notes on meetings, etc. 1985-1986 Includes Society of Chemical Industry meeting, 19 June 1986. Large format notebook used byLilly's research student R.C. Eglin 1985-1987 Hardback Federation of Biotechnology (EFB) meetings, etc. notebook notes used for on European ?late 1980s Probably in use late 1980s. Small format hardback notebook used for lists of things to do,etc. [1989]-1990 Hardback notebook used for notes of meetings with UCL colleaguesre research, etc. 1989-1991 Hardback notebook used for notes for meetings with UCL colleagues re research, building, equipment, IRC, Link, etc. 1990-1992 M.D.Lilly NCUACS150/7/06 15 Notebooksand research notes, B.1-B.46 For IRC see C.152-C.194. For Link programme see B.26, B.27, C.236-C.304, C.930- C.941. Small hardback notebook usedfor lists of things to do, etc. 1991-1992 Small format hardback notebook used for bibliographical references from the front and from the back for notes re Link programme. c.1993 - 1994 A4 size hardback notebook used for notes on meetings with UCL colleagues: fermentation research, transketolase, IRC strategy, Link etc. meeting, training 1993-1997 Aé4size softback notebook: includes notes on ‘Meeting on Labview 17/6/94’ 1994 backed Soft bibliographical references 7" ‘9" x Exercise Book’ used for ? 1995 Small format hardback notebook identified as ‘MDL’s last notebook from 11/10/1997’ 1997-1998 Binderused for bibliographical references Softback notebook usedfor bibliographical references Hardback notebookusedfor bibliographical references Address book with manuscript note ‘This seems to cover almost the whole of MDL’s research period at UCL’ Loose items enclosed. N.d. N.d. N.d. N.d. B.25 B.26 B.27 B.28 B.29 B.30 B.31 B.32 B.33 B.34 M.D.Lilly NCUACS150/7/06 Notebooksand research notes, B.1-B.46 B.35-B.46 RESEARCH NOTES B.35-B.36 ‘VI. Control Systems’ Contents of folder so inscribed divided into two for ease of reference: background material, latest publication date 1964. manuscript draft and printed 16 1965-1997 N.d. B.37 ‘Active (incomplete but not active)’ Projects’, ‘Projects completed’ and ‘Projects 1970 Paperssotitled found clipped together. The papers seem to form a record of the research situation in December 1970. B.38 ‘4 Phase Fermentations’ N.d. Contents of folder so inscribed: manuscript and typescript notes, background printed papers. Latest bibliographical reference in the notes, 1972. B.39-B.40 ‘Fermentation’ 1973, n.d. Contents of folder so inscribed divided into two for ease of reference: manuscript list of bibliographical references, offprints, etc. At B.40 are ‘Tables and figures Topic No.1 Growth and Metabolism Fermentation Technology’ by C.L. Cooney, Massachusetts Institute of Technology, 30 July - 3 August 1973. B.41 ‘Progesterone Conversion’ 1968-1978 Contents of folder so inscribed: manuscript and typescript notes, correspondence, etc. It is possible that the contents are more diverse than the foldertitle suggests. B.42 ‘1000 Litre Data’ N.d. Contents of folder so inscribed: mansucript data and plots. M.D.Lilly NCUACS150/7/06 17 Notebooksandresearch notes, B.1-B.46 B.43-B.46 Shorter notes and drafts found loose and in no order. 1965-1997 Many papers undated. Four folders. M.D.Lilly NCUACS150/7/06 18 SECTION C UNIVERSITY COLLEGE LONDON, C.1-C.971 1957-2002 section This aspects development of Biochemical Engineering at UCL. documents significant of the Important dates include: 1954 Joint research undertaken between the Departments of Biochemistry and Chemical Engineering. 1958 Guinness lecturer (Dr F. Webb) appointed. 1964 Biochemical Engineering Section established. 1976 Biochemical Engineering’. Departmental name changed to ‘Chemical and Recognised as a national centre by Science and 1987 Engineering Research Council (SERC). 1990 Construction of Advanced Centre started. Interdisciplinary Research Centre (IRC) supported 1991 by SERC. 1998 Formation of two Departments - the Department of Biochemical Engineering and Department of Chemical Engineering Process Engineering. School part of the - as of Teaching courses developed asfollows: 1959 Postgraduate Diploma Course (1year). 1966 MSc approved by University. 1973 BEng (3 year) started. 1977 Annual one-week post-experience course started. The material is arranged asfollows: C.1-C.40 ‘HISTORY’ C.41-C.151 ADVANCED CENTRE FOR BIOCHEMICAL ENGINEERING (ACBE) C.152-C.194 INTERDISCIPLINARY RESEARCH CENTRE (IRC) C.195-C.472 RESEARCH GRANTS M.D.Lilly NCUACS150/7/06 19 University College London, C.1-C.971 C.473-C.757 TEACHING AND TRAINING C.758-C.891 PERSONNEL C.892-C.971 MISCELLANEOUS C.1-C.40 ‘HISTORY’ 1957-1998 Contents of folders and box folders labelled ‘history’ or ‘historical’. C.1-C.6 ‘UCL Historical’ Contents of folder so inscribed. C.1 ‘The future prospects of Biochemical Engineering University College’ in 8pp typescript and manuscript draft with manuscript additions and corrections. 1957-1989 [21963] C.2 Papersfound clipped to the preceding: 1957-1966 ‘Biochemical Engineering Equipment’, 3pp typescript + 1p typescript headed ‘Dr Crook’s original draft’. N.d. ‘Project Reports for Period ist Sept. 1965 - 31st Aug. 1966’, 4pp typescript. ‘Biochemical Engineering Education and Research’ by M.C. Reece, The Industrial Chemist, July 1957. Off-print with manuscript underscoring. College London University Engineering Department Syllabus of the 1 year Postgraduate Coursein Biochemical Engineering, 1p duplicated typescript, n.d. Chemical C.3 Correspondence and papers 1970-1972 Includes ‘Supplementary Report to the Enzyme and M.D.Lilly NCUACS150/7/06 20 University College London, C.1-C.971 Technology Committee’ by Lilly and P.Dunnill. Correspondence and papers 1983-1989 Principally re research and funding. Lists of [Lilly's] research grants, committee and panel membership and consultancies N.d Thelists were prepared after 1989. Manuscript engineering at UCL and_ typescript drafts re biochemical N.d. Includes ‘Future Developments in Biochemical Engineering at UCL A Discussion Paper’, 12pp manuscript draft + ‘Appendix II Biochemical Engineering Personnel’. Architect's drawings for UCL Engineering Faculty N.d. See also C.38. ‘Biochemical Engineering Accommodation and Equipment’ 1963 1p typescript 25 November 1963. ‘Memorandum on state and future biochemical engineering at University College London’ present the of 1963 C.3 C.4 C.5 C.6 C.7 C.7 2pp duplicated typescript memorandum by ‘EB’ [?Eric Baldwin], 3 December 1963, enclosing eight documents by M.B. Donald, E.M. Crook, Lilly and others. C.8, C.9 Correspondence and papers 1967 Twofolders. Includes ‘The Supply of Enzymes for Industrial and Medical Use A Report submitted to the Science Research Council’ byLilly, February 1967. M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.10 ‘Insolubilised Amyloglucosidase at U.C.L.’ 4pp typescript ‘8.10.68’ + results and graphs. 21 1968 N.d. C.11 C.12 C.13 ‘Department of Chemical Engineering, University College London Biochemical Engineering Section’ 5pp typescript + publications list. reference, 1968. Latest bibliographical Correspondencere projects and funding October 1969 Correspondence and papers re Enzyme Technology Research Group 1970-1973 C.14-C.18 ‘Historical re teaching’ c. 1972-1995 Contents of folder so inscribed divided into five for ease of reference: lecture lists, course summaries, timetablesetc. Many undated papers. C.19 C.20 C.21 C.22 Correspondence and papers re visits of students to Thames Water Authority Crossness Sewage Treatment Works 1973-1977 Correspondence on biotechnology between Lilly and J.M. Ashworth, Chief Scientist, Cabinet Office Central Policy Review Staff 1977 ‘Enzymes Chemistry and Industry, 1 April 1978 industrial catalysis and - a discussion’, 1978 Those taking part in the discussion included Lilly, Peter Dunnill, also of UCL, and Eric Crook of St Bartholomew's Hospital Medical School, formerly of UCL. Correspondence in biochemical engineering and biotechnology at UCL and developments papers and re 1980-1982 M.D.Lilly NCUACS 150/7/06 22 University College London, C.1-C.971 nationally. Includes copy of letter to the Prime Minister, 7 January 1981, about biotechnology in the UK (Lilly was a co- signatory) andletter from Lilly to the Provost UCL, 8 March 1982, about ‘plans for the creation of a College Centre for Biochemical Engineering and Technology’. C.23 ‘Dev of SERC Centre’ 1983-1986 Contents of folder so inscribed: correspondence and papers re developmentof UCL as a centre for Biochemical Engineering and related matters. See also C.952-C.954 C.24 C.25 C.26 Correspondence University Committee additional equipment grant for 1985/86 papers and re_ Grants 1985 The Government made available the additional equipment grant ‘for the improvement of laboratory and equipment provision in a few carefully selected centres of research’. The selection committee under Sir Andrew Huxley put forward list of research groups including that of Lilly and Peter Dunnill. UCL Biochemical Engineering Newsletters nos 2 and 3 1985-1986 Application to Wolfson Foundation in creation Engineering (ACBE) at UCL Advanced Centre an of respect of the Biochemical for 1986 C.27-C.29 ‘History Engineering] / ACBE [Advanced Centre for Biochemical 1989 and n.d. Contents of folder so inscribed divided into three for ease of reference: photographs of equipment and architect’s models, and architect’s drawings. The drawings are dated August - October 1989. C.30 ‘Biochemical Engineering at UCL’ 1992 M.D.Lilly NCUACS150/7/06 23 University College London, C.1-C.971 1p handoutlisting some important dates, teaching courses, academicstaff and research areas. Conference des Grandes Ecoles Visit to the Advanced Centre for Biochemical Engineering UCL, 17 February 1993 1993 Contents of folder inscribed ‘history’: correspondence and papersrevisit. Opening Engineering, 8 September 1993 the Advanced of Centre for Biochemical 1993 Accountof the opening in ‘bioBulletin’ the newsletter of the biotechnology directorate SERC, November 1993. ‘Undergraduate Biochemical paper’ Engineering - a position 1995 Copy of position paper ?by Nigel Titchenor-Hooker, with Lilly's undergraduate biochemical engineering, 25 November 1995. manuscript comments on Department UCL Engineering Strategic Plan 1997-2000 Chemical of and Biochemical 1997 Correspondence and papers re formation of a separate UCL Department of Biochemical Engineering 1997-1998 C.31 C.32 C.33 C.34 C.35 C.36 ‘The future of biochemical engineering at UCL’ 3pp typescript. Incomplete. C.37 ‘Chemical & Biochemical Summary of Essential Points made by Department in support of its claim for an Increased Recurrent Grant’ Engineering 3pp typescript + ‘Comparison of Departmental Resources .. with Other Departments represented on the Working Party’. N.d. N.d. M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.38 Architect’s drawing See also C.6. 24 N.d. C.39, C.40 Printed papers re biochemical engineering at UCL and more generally. 1984 and n.d. Twofolders. C.41-C.151 ADVANCED ENGINEERING (ACBE) CENTRE FOR BIOCHEMICAL 1983-1997 of etc ring binders, box folders, Contents entitled ‘Advanced Centre for Biochemical Engineering’ or ‘ACBE’: correspondence and papers, principally relating to the creation of purpose-designed facilities for training and research activities in biochemical engineering at UCL in an ‘Advanced council assessment, 1996-1997. 1986-1995 and research Centre’, Include drawings and plans, minutes of meetings and much photocopied material, notes, drafts, etc sent to Lilly by UCL biochemical engineering colleagues. Correspondents engineering colleagues, architects, funders, etc. Provosts include UCL, biochemical The contents of a number of boxes and folders were found in considerable disorder and included much undated material, the assignment of whichis tentative. See also C.26, C.27-C.29, C.32. C.41 ‘Advanced Preliminary Architectural, Engineering & Costing Study’ Biochemical Engineering A Centre for April 1986 In original binder. The study was prepared Engineering Limited. by Matthew Hall Norcain C.42-C.50 ‘A.C.B.E A-L’ 1986-1989 Contents of ring binder so inscribed divided by titled M.D.Lilly NCUACS150/7/06 25 University College London, C.1-C.971 subject dividers. A subject divider inscribed ‘Chemap’ did not correspond to any surviving papers. Correspondence with industrial and commercial concerns relates to fund raising and research cooperation. C.42 C.43 C.44 Miscellaneous papers at front of binder including list of ‘Contacts [in respect of fund raising] made up to mid-June 1987’ 1986-1987 ‘ACBE Appeal’ ‘Alfa-Laval’ 1986-1987 1986-1989 Engineering Alfa-Laval equipment manufacturer in respect of fermentation and bioprocessing technology. Ltd was an C.45 ‘Archaeology Appeal’ 1986-1987 Lilly was a memberof the Executive Appeal Committee for the Archaeological Conservation Centre. C.46 ‘Architects’ Sub-Committee (architect, general)’ 1986-1988 Lilly was a member of the Sub-Committee. C.47 ‘Bayer’ Oneletter only. ‘Beechams’ C.48 ‘British Gas’ 1988 1986-1988 1988-1990 M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.49 ‘Davy McKee’ ‘General correspondence, etc.’ Oneletter only. letter from Carbon of R. Coleman of the Biotechnology Unit of the Laboratory of the Government Chemist. Lilly to ‘Gist-Brocades’ ‘Glaxo’ C.50 ‘Wensley Haydon-Baillie’ ‘ICI’ Leverhulme Trust Oneletter only. 26 1988 1986 1987-1988 1987 1988 1986, 1988 N.d. C.51-C.63 ‘ACBE M-2’ 1984-1989 Contents of ring binder so inscribed divided by titled subject dividers. A subject divider inscribed ‘Tel-Aviv University’ did not correspond to any surviving papers. Correspondence with industrial and commercial concerns relates to fund raising and research cooperation. Copies of correspondence between Provost UCL and Wolfson Foundation found looseat front of binder Marks & Spencer Matthew Hall / Stearns Catalytic’ Includes cost estimates for the ACBE. 1989 1987 1986 C.51 C.52 C.53 M.D. Lilly NCUACS150/7/06 University College London, C.1-C.971 C.54 ‘Merck’ ‘Porton International’ Oneletter only. 27 1988 1987 C.55 ‘Project Sub-Committee’ 1986-1987 Lilly was a member of the Project Sub-Committee - Proposed Developmentof the Gordon StreetSite. C.56 C.57 C.58 C.59 ‘Sainsbury’ ‘Sasakawa Foundation’ ‘Smith, Kline & French’ ThomasHarris & Associates Re drawing up feasibility development. strategy for financing the 1989 1986 1987 1988 C.60 ‘Unilever’ 1984-1988 C.61, C.62 ‘UGC [University Grants Committee]’ 1986-1988 Twofolders. C.63 ‘Wellcome’ ‘Wolfson’ 1986, 1988 1986 M.D.Lilly NCUACS150/7/06 28 University College London, C.1-C.971 C.63A ‘The Creation of an Advanced Centre for Biochemical Engineering’ 1987 11pp typescript + appendices. Bound volume C.64 for ‘Conceptual Biochemical Engineering’ Study the Advanced Centre for April 1988 Prepared by Davy McKee‘A Davy Corporation Company’. In original binder. C.65-C.66 Contents of untitled ring binder divided into two for ease of reference 1989-1990 Includes manuscript notes and drawingsbyLilly. C.67 ‘Report of Design Requirements’, February 1990 In original binder. Prepared by Davy McKee. See also C.68. C.68 ‘Comments on DMK Document (Revision 25/2/90’ 1) MDLilly 1990 2pp manuscript notes found at the front of the Report at C.67. C.69-C.73 Contents of untitled binder divided into five for ease of reference 1990 Letter from Davy McKee, 20 March 1990, enclosing a set of documents, principally drawings ‘at preliminary status only’. C.74 ‘Technical Package’ 1990 Contents of binder so inscribed: ‘client technical brief M.D.Lilly NCUACS150/7/06 29 University College London, C.1-C.971 prepared by Davy McKee, August 1990. original binder. Retained in See also C.75. C.75 Papers found loose at the front of ‘Technical Package’ binder 1990 C.76-C.143 General correspondence and papers 1985-1997 C.76 - C.77 1985 1986 C78-C.79 1987 Twofolders. C.80-C.83 1988 Four folders Undated paperstentatively assigned to 1988 are at C.83. C.84-C.94A 1989 Twelvefolders. C.95-C.102 1990 Eightfolders. C.103-C.113 1991 Eleven folders M.D.Lilly NCUACS150/7/06 30 University College London, C.1-C.971 C.114-C.116 1992 Three folders. C.117-C.122 1993 Six folders. C.117 includes papers for visit of G. Robinson, Chief Advisor on Science and Technology, Department of Trade and Industry to UCL, 14 January 1993. C.123 C.124 C.125 1994 1995 1996 C.126-C.141 1997 Sixteen folders. C.142, C.143 N.d. Twofolders. C.143 At biochemical engineering at UCL and the ACBE. transparencies are for presentation on C.144-C.151 Engineers’ drawings 1983-1990 Eightfolders. M.D.Lilly NCUACS150/7/06 31 University College London, C.1-C.971 C.152-C.194 INTERDISCIPLINARY RESEARCH CENTRE(IRC) 1989-1997 Contents of box folders, ‘IRC’: correspondence and papersre establishment, programme and assesmentof the IRC. etc inscribed folders, There is some overlap with materials found in ‘ACBE’ folders. The assignmentof undated papersis tentative. In 1991 UCL becamethe IRC for Biochemical Engineering (Director Peter Dunnill) with a ten year remit to develop an interdisciplinary programme of research and teaching. In 1995, following a review of the IRC the Biotechnology and Biological Sciences Research Council decided that it should be ‘converted to a 4-year funding cycle, with the budget being set using the Council’s funding formula for institutes’. The Centre was assessed in 1996 and received a Visiting Group in 1997. C.152 1989 C.153-C.157 1990 Five folders. C.158-C.165 1991 Eight folders. C.166-C.175 1992 Includes much undated material found in great disorder. Ten folders. C.176 1993 C.177-C.181 1994 Five folders. M.D.Lilly NCUACS150/7/06 32 University College London, C.1-C.971 C.182, C.183 1995 Twofolders. C.184 1996 C.185-C.189 1997 Five folders. C.190-C.194 N.d. Five folders. C.195-C.472 RESEARCH GRANTS 1962-1998 Contents of Lillyss boxes labelled ‘Research Grants’: correspondence and papers re funding of research, etc in biochemical engineering at UCL byLilly and colleagues. The material is presented as follows: C.195-C.387 By funding body or programme C.388-C.401 By research contract client C.402-C.459 By researchtopic C.460-C.472 Patents C.195-C.387 By funding body and programme 1962-1998 Alphabetical sequence C.195-C.201 Biotechnology and Biological Sciences Research Council 1992-1997 M.D.Lilly NCUACS150/7/06 33 University College London, C.1-C.971 C.195-C.197 ‘Project with Warwick’ 1994-1995 reference: correspondence and Contents of folder so inscribed divided into three for ease of grant proposal entitled ‘Large-scale Biotransformation for the Recycling of Industrial By-Products of Speciality Chemical Manufacture’. This grant proposal was made under the ‘Cleaner Synthesis for Industry’initiative and submitted by D.H.G. Crout and P.Critchley of the University of Warwick andLilly and J.M. Woodley of UCL. papers re C.198 ‘Clean Technology’ 1992, 1994 Contents of folder so inscribed: correspondence and papers re Research Councils’ interest in promotion of research towards new clean technologies. ? relates to ‘Project with Warwick’ (C.195-C.197). C.199 ‘BBSRC’ Contents research studentships. of folder so inscribed: correspondence re C.200 ‘TK [transketolase] application’ Contents of folder so inscribed: papers re application by J.M. Ward, J.M. Woodley and Lilly titled ‘Recombinant transketolase with broad industrial potential’. C.201 ‘1998 PhD Proposal’ Drafts for application. 1996 1996 1997 C.202-C.207 Departmentof Trade and Industry 1983-1985 Contents of folder inscribed ‘DTI’ divided into six for ease of reference: principally research reports. See also Link Programme. M.D.Lilly NCUACS150/7/06 34 University College London, C.1-C.971 C.208, C.209 Engineering and Physical Sciences Research Council (EPSRC) 1995-1996 Contents of folder inscribed ‘Polyleucines Exeter [crossed out] (Roberts)’ divided into two for ease of reference: application and related papers. The project wastitled ‘Scale up of asymmetric epoxidation reactions polyleucine based catalysts’ and the investigators were S.M. Roberts (Liverpool), Lilly and J.M. Woodley. using C.210-C.235 European Commission (EC) C.210-C.217 ‘Biochemical engineering programme’ 1979-1998 1979-1985 Community programme for Contents of folder so inscribed divided into eight for ease of reference: correspondence and papersre proposal for a European and developmentin biochemical engineering and specific UCL research proposal within the framework of the programme on ‘the development of multiphase bio-reactors for the modification of oils and fats. research C.218 ‘FP4 Proposal’ 1994-1995 Contents of folder so inscribed: correspondence and papers re proposed joint EC project with DSM Research in the Netherlands on two phaseliquid biocatalysis. C.219-C.234 ‘Research Grant (Last one he worked on) FP4 - Proposal BVMO [Baeyer-Villiger Mono-oxegenases]’ 1996-1997 Contents of folder with post-it note so inscribed divided into sixteen for ease of reference: correspondence and papers re proposal titled ‘Biotransformations using Baeyer-Villiger Mono-oxegenases’. Project partners came from the UK and France, Germany, Italy, the Netherlands and Switzerland. These papers were found in considerable disorder and have been presentedin the order found. See also C.235. M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.235 ‘EC Grant Proposal’ of Contents folder manuscript notes re proposal. See also C.219-C.234. inscribed: so_ correspondence, Baeyer-Villiger Mono-oxegenases 35 1998 C.236-C.304 Link Programme 1988-1997 This programme wasjointly funded by the Department of Trade and Industry and the Science and Engineering Research encouraging collaborative university-industrial research projects. Council view with the to four ICI] relate to proposal Biological (accepted) SmithKline Products engineering - a biochemical companies for a The papers consortium UCL/Industry Beecham involving (Zeneca Pharmaceuticals, BioProducts), Shell Research and Unilever Research. The objective was to support biochemical engineering research and training at UCL, initially for four years, by providing funds for pre-competitive research, provision of research facilities and assistance with training. The start date was 1 September 1990 with a completion date of 30 August 1994. Much of the material was found in labelled folders which have been used as the basis of arrangement. However, there was also a large number of loose papers which have been presented in a chronological sequence as far as possible. See also C.930-C.941, F.362-F.367. C.236-C.243 ‘LINK - Setting Up - 1988/1989’ 1988-1990 Contents of folder so labelled divided into eight for ease of reference: correspondence and papers. C.244-C.250 ‘LINK - Setting up - 1990’ 1990 Contents of folder so labelled divided into seven for ease of reference: correspondence and papers. M.D.Lilly NCUACS150/7/06 36 University College London, C.1-C.971 C.251-C.257 ‘LINK Agreement / Offer Letter / RG2 / E14 / Original Proposals etc’ 1989-1994 Contents of folder so labelled divided into seven for ease of reference: correspondence and papers. See C.256, C.257 for overheads for presentation including transparencies. At C.257 is programme for ‘Final LINK Programme Presentations to Unilever (Colworth) July 27 1994’. C.258-C.262 ‘LINK DTI Proposal / Offer Letter’ 1989-1993 Contents of folder so inscribed divided into five for ease of reference: correspondence and papers. C.263 ‘LINK Costings’ 1989-1990 Contents of folder so labelled: manuscript notes, summary of programme costs, etc. C.264 ‘Institute Department of Trade and Industry Companies Shell’ 1990-1994 Contents of papers. folder so labelled: correspondence and C.265 ‘LINK Management Committee Meetings’ 1990-1991 Contents of folder so inscribed: correspondence, agendas etc. C.266 ‘LINK Management Committee Minutes’ 1990-1994 Contents of folder so labelled. C.267-C.270 ‘LINK’ 1991 Contents of folder so labelled divided into four for ease of reference: correspondence and papers. M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.271, C.272 ‘UCL LINK’ Contents of folder so labelled divided into two for ease of reference: papers probably for LINK presentation to SB [SmithKline Beecham] Worthing, Sussex, 31 July 1994. C.273 ‘(Overhead) Transparencies - IRC’ Contents of folder so inscribed: includes Lilly’s manuscript notes anddrafts. Found with LINK papers. 37 1994 N.d. C.274-C.304 General correspondence and papers 1988-1997 C.274 1988-1989 C.275 1990 C.276-C.281 1991 Includes project reports. Six folders. C.282-C.292 1992 Includes project reports. Eleven folders. C.293, C.294 1993 Includes transparencies for Biochemical Engineering LINK meeting. scientific presentations at Twofolders. C.295-C.299 1994 M.D.Lilly NCUACS150/7/06 38 University College London, C.1-C.971 Includes papers for ‘Progress Report 8 of the Biochemical Engineering Consortium’. Five folders. 1995 1997 C.300 C.301 C.302-C.304 N.d. Threefolders. C.305-C.320 National Research Development Corporation 1968-1978 See also C.392-C.395. C.305, C.306 ‘NRDC General’ 1968-1975 Contents of folder so inscribed divided into two for ease of reference: correspondence and papers re support for work at UCL by the NRDCand patent applications. C.307-C.317 ‘NRDC Patents’ 1968-1978 Contents of folder so inscribed divided into eleven for ease of patent applications etc. . reference: correspondence and papers re C.318 ‘Porous reactors’ 1969-1971 Contents of folder so inscribed: correspondence and papers re patent application arising from work on porous reactors. C.319 ‘NRDC Grant - EB-J2’ 1969-1971 Contents of folder so inscribed: correspondence and M.D.Lilly NCUACS 150/7/06 39 University College London, C.1-C.971 papers re NRDC funded project on polymer bound enzymesincluding report to NRDCon final year of project. C.320 ‘N.R.D.C. Patents’ 1969-1971 Contents of folder so inscribed: correspondence and papers re patent applications. C.321-C.375 Science Research Council / Science and Engineering Research Council 1962-1994 Documentation ofLillys SRC / SERC grants are presented in an approximately chronological order. Included in the sequence are joint applications with colleagues at UCL or otherinstitutions and applications by UCL colleagues sentto Lilly for information. ‘EB’ reference numbersin the catalogue entries relate to UCL’s owngrant referencing system C.321-C.323 SRC grant B/SR/833 ‘Biochemical Fuel Cells’ 1962-1970 Contents of folder inscribed ‘Fuel Cells’ divided into three for ease of reference: correspondence and papers. The initial application was made to the SRC’s predecessor organisation the Department of Scientific and Industrial Research Donald’s resignation from UCL in 1966 the details of the grant were amended to provide for the research to be conducted by Lilly and P.N. Rowe. Donald. (DSIR) M.B. On_ by C.324-C.326 SRC grant GR/A/87081 ‘Effect of cycling dissolved gas concentrations on microbial product formation’ 1978-1982 Contents of folder inscribed ‘SERC grant Effect of Cycling EBC7’ reference: correspondence and papers including application and reports. divided three ease into for of C.327 SRC grant application ‘The Stability of Biological Catalysis in Reactor Systems’ 1981 M.D.Lilly NCUACS150/7/06 40 University College London, C.1-C.971 Application only. C.328 SRCgrantapplication ‘A Biochemical Engineering Study to Improve Protein Processing’ 1981 Application only. The applicant wasLilly’s UCL colleague Peter Dunnill. C.329-C.332 Miscellaneous correspondenceand papers re SRC grants 1969-1981 Contents of folder inscribed ‘SRC Research Grant Claim’ divided into four for ease of reference: includes grant applications. C.333 SERCgrant GR/B 54520‘Pilot-Scale Fermentation’ 1980-1982 Contents of folder so inscribed ‘SERC Grant “Pilot-Scale Fermentation” ’: application, report to SERC, etc. C.334 SERC grant GR/B/60637 Biocatalysts in Multi-Liquid Phase Reactions’ ‘Kinetics & Stabilities of 1981-1985 Contents ofLilly's folder inscribed ‘EB.D8.84 SERC Grant “Multi-phase Reactions” ’: includesfinal report. C.335 SERC grant GR/B 95707 ‘Stability Constructed Culture’ Plasmids in Chemostat and Pilot of Natural and Plant 1981-1985 Contents of Stability” ’: grant applications, final report etc. folder inscribed ‘SERC Grant “Plasmid This was a joint UCL (Lilly and P.H. Clarke) / Polytechnic of Central London (G.Holt) programme. C.336 SERC grant GR/C 17628 ‘The Integration of Fermentation and Subsequent Processing Operations for Microbial Protein Products’ 1982-1985 Contents of folder inscribed application by N.M. Fish and Lilly, etc. ‘Fish & Lilly EB.E6.8A’: M.D.Lilly NCUACS 150/7/06 41 University College London, C.1-C.971 C.337-C.339 SERC grant GR/C 70937 ‘Microbial Halogenation’ 1982-1988 Contents of folder inscribed ‘Microbial Halogenation SERC GR/C 70937’ divided into three for ease of reference: applications, research report etc. The application made in 1982 (start date 1/1/83) was submitted by the University of Kent on behalf of the S.E. England Biotechnology Consortium (A.T. Bull, G. Holt and Lilly). An award was notinitially recommended and a revised application was submitted. See also C.340-C.342, C.343. C.340-C.342 SERC grant GR/C 70937 ‘Microbial Halogenation’ 1984-1987 Contents of untitled folder divided into three for ease of reference: research reports, final report. See also C.337-C.339, C.343. C.343 SERC grant GR/C 70937 ‘Microbial Halogenation’ 1988 Contents of correspondence. untitled folder: final report and related The final report was much delayed because of Lilly’s serious illness. See also C.337-C.339, C.340-C.342. C.344 SERC grant GR/C 99822 product recovery’ ‘Fermentation and protein 1984-1986 ‘SERC Grant EBF4’. application, research report, etc. Contents of folder so inscribed: The investigators were N.M. Fish, Lilly and M. Hoare. C.345, C.346 SERC ‘Spinks’ Studentship in Process Engineering in Biotechnology liquid-phase biocatalytic reactors’ ‘Design Award of two 1984-1985 Contents of untitled folder divided into two for ease of reference: application and related correspondence. M.D.Lilly NCUACS150/7/06 42 University College London, C.1-C.971 C.347, C.348 SERC grant GR/D/32895 ‘Kinetics of biological reactions involving a reactant-containing organic phase’ 1984-1988 ‘SERC grant EB.90 (1.7.85 - 30.6.88)’. Contents of folder so inscribed divided into two for ease of reference: application, grant report etc. C.349 SERC grant GR/D 75007 proteins during fermentation and downstream processing’ ‘Monitoring of enzymes and 1985-1988 Contents of folder application, research grant report, etc. inscribed with the project title: C.349A SERC_ Biotechnology biocatalyst interactions’ Studentship ‘Organic phase- 1985-1986 Contents of folder inscribed with projecttitle: application, etc. C.350-C.360 ‘SERC’ 1986-1988 Contents of box folder so inscribed divided into eleven for ease of reference: includes drafts and transparencies for presentations. The papers are presentedin the order found. In January 1986 the SERC Biotechnology Directorate invited proposals from universities for the development of major disciplinary research programmes in biochemical in May and in engineering. UCL was. September was invited Biochemical Engineering Centre and begin the process of turning UCL’s proposal into a formal grant application. See C.361, C.362 shortlisted to become a_ C.361, C.362 SERC GR/E 27027 Engineering’ ‘Integrated Studies in Biochemical 1986-1989 Contents of folder inscribed ‘Integrated studies in biochem. eng (MDL{illy]/PD[unnill]/CRT[homas]/MH[oare]/NMF[ish])’ divided into two for ease of reference: applications, special research grant announcement,interim report, etc. This application arose from the selection of UCL as one of two centres for special SERC funding of biochemical engineering. For the background to this application see M.D.Lilly NCUACS150/7/06 43 University College London, C.1-C.971 C.350-C.360. C.363 SERC Biotechnology Directorate research studentship (quota) ‘The effect of immobilization on organic phase - enzymeinteractions’ 1986-1987 Contents of folder inscribed with project title: includes application. C.364 SERC CASE [Co-operative Awards in Science and Engineering] Awards 1990-1994 Contents of folder inscribed ‘CASE Awards’: application, correspondencewith Pfizer Ltd. C.365-C.368 SERC IRC Studentships 1990-1992 Contents of folder inscribed ‘IRC Studentships 1991, 1992’ divided into four for ease of reference: includes PhD proposals and correspondence and papersrejoint training of PhD students with other universities. C.369-C.372 SERC application by A.P. Ison UCL and M. Bushell, Microbial Physiology Group, University of Surrey ‘The Influence of Hyphal Morphology on Antibiotic Production in Submerged Culture’ 1991-1993 Contents of folder inscribed ‘Mike Bushell’ divided into four for ease of reference: correspondence and papers re joint research proposal of Ison and Bushell. The application to the SERC was rejected in November 1992 ‘in its present form’ and resubmission invited. C.373 SERCgrant application ‘The Developmentof a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’ 1992 Contents of folder inscribed ‘UCL/Exeter SERC Grant Application grant applications from UCL (J.M. Woodley and J.M. Ward) and Exeter (N.J. Turner and A.J. Willetts). 1992’: Lilly's role in the proposed project was consultative. M.D.Lilly NCUACS150/7/06 44 University College London, C.1-C.971 C.374 C.375 SERC Biotechnology Directorate Research Studentship ‘Downstream Processing from Transketolase Catalysed Biotransformations’. 1992-1993 Contents Research Studentship 1993’: includes application. inscribed ‘BT of folder [Biotransformation] The applicant was J.M. Woodley. for Visiting Fellowship Research 1994 SERC Applications Grants Twoapplications only. The proposers were A.P. Ison and J.M. Woodley. C.376-C.387 University Grants Committee C.376-C.383 ‘Grants (Various)’ 1982-1992 1982-1992 Contents of folder so inscribed divided into eight for ease of reference: correspondence and papers principally re UGC earmarked support for biotechnology and review of the UGC’s biotechnologyinitiative. C.384-C.387 ‘UGC Research Plan (Biotechnology) 1984-1988 Contents of folder so inscribed divided into four for ease of reference: includes drafts of ‘College Research Plan for Biotechnology’. C.388-C.401 By research contract client C.388-C.395 Beecham Research Laboratories C.388-C.390 ‘EBJ4 Beecham Grant’ 1968-1993 1968-1975 1968-1971 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers including letter agreement, research reports, etc. The project involved work with the enzyme penicillin amidase. M.D.Lilly NCUACS150/7/06 45 University College London, C.1-C.971 C.391 ‘Beecham EBJ4 Extension’ 1971-1973 Contents of folder so inscribed: includes ‘Proposal for extension to project supported by Beecham Research Laboratories’, research report, research agreement,etc. C.392-C.395 ‘Ferromagnetic Supports’ 1971-1975 Contents of folder so inscribed divided into four for ease of reference: correspondence and papersre patent questions with Beechams and National Research Development Corporation. C.396, C.397 Mead Research USA 1989-1991 Contents of folder inscribed ‘Mead’ divided into two for ease of reference: correspondence and papersincluding research reports. The project was titled ‘Reactor Evaluation for Enzymic Phenol Oxidations in Aqueous Organic Reaction Media’. C.398-C.401 Sumitomo Chemical Company Japan 1990-1993 Contents of folder inscribed ‘Sumitomo’ divided into four for ease of reference: correspondence and papers re arrangements including quotation. The project was described as carried out by Sumitomo Chemicals’ Researcher’. ‘Research at UCL to be C.402-C.459 Byresearch topic C.402 ‘Antibiotic Process Mtgs’ 1972-1997 1996 Contents of folder so inscribed: minutes of meetings, etc. In fact the folder contained minutes of only one ‘Antibiotic Process’ The other minutes are headed ‘Streptomyces’ meetings. meeting. M.D.Lilly NCUACS150/7/06 46 University College London, C.1-C.971 C.403-C.408 ‘Baeyer-Villiger 1992-1996 Contents of folder so inscribed divided into six for ease of reference: correspondence and papers re Baeyer-Villiger Monooxygenase research in collaboration with University of Exeter (S.M. Roberts). C.409-C.412 ‘Biotransformation Research’ 1994-1997 Contents of folder so inscribed divided into four for ease of reference: includes agenda and papersfor ‘Third Annual Research Meeting’ on ‘ The Developmentof a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’, 19 December 1995, etc. C.413 ‘Cholesterol Project (Northwick Park)’ and ‘Northwick Park Clinical Centre (Project)’ 1972 Contents of folder so inscribed: correspondence and papersrelating to Cholesterol Oxidase Project, 1972. C.414-C.422 ‘Collaboration with Exeter’ 1990-1996 Contents of folder so inscribed divided into nine for ease of reference: correspondence and papers re collaborative project ‘The Development of a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’. These papers were found in considerable disorder and are presented as found. See also C.423-C.425. C.423-C.425 ‘Exeter Visit’ 1992-1995 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re collaboration with Exeter ‘The Developmentof a Biocatalytic Process for Large Scale Carbon-Carbon Bond Synthesis’. Many of the papers are headed ‘Transketolase’ ‘Transketolase Project’. or M.D.Lilly NCUACS150/7/06 47 University College London, C.1-C.971 C.426 ‘Fermentation RAG [Research Advisory Group] 1996 Contents of folder so inscribed: papers for meeting, 8 November1996. C.427 ‘Flexible Biotransformations’ 1994 Contents of folder so inscribed: includes notes sentto Lilly for _for biotransformation. bioprocessing comment flexible on C.428-C.436 ‘Halogenation’ 1983-1985 Contents of folder so inscribed divided into nine for ease of reference: includes research reports and bibliographical references. C.437-C.445 ‘Halogenation’ 1985-1986 Contents of binder so inscribed divided into nine for ease research of reports, bibliographical references. reference: research notes, C.446, C.447 ‘1982 Plasmid Stability’ 1982-1985 Contents of folder so inscribed divided into two for ease of reference: includes drafts of case for support of proposed investigation ‘Stability of Natural and Constructed Plasmids in Chemostat and Pilot Plant Culture’. C.448, C.449 ‘Protein Processing’ 1986-1989 Contents of folder so inscribed divided into two for ease of reference: papers re SERC grantofLilly’s UCL colleagues P. Dunnill and M. Hoare ‘A biochemical engineering study to improve the separation of biological material, especially proteins’ C.450, C.451 ‘Transketolase Research Grant’ 1994 Contents of plastic folder so labelled divided into two for ease of reference: ‘2nd Annual Report (1994)’ and papers re organising December 1996 research meeting. M.D.Lilly NCUACS150/7/06 48 University College London, C.1-C.971 These papersrelate to collaboration with the University of Exeter ‘The Development of a Biocatalytic Process for Large Scale Carbon-Carbon- Bond Synthesis’. The annual report comprises presentations made at the 2nd Annual Research Meeting, 15/16 December 1994. C.452, C.453 ‘Transketolase’ 1994-1995 Contents of folder so inscribed divided into two for ease of reference: research meetings, etc. correspondence and papers re_ These papersrelate to collaboration with the University of Exeter ‘The Development of a Biocatalytic Process for Large Scale Carbon-Carbon- Bond Synthesis’. Included at C.453 is a photograph of ‘Carbons United’ including Lilly. C.454-C.459 ‘TK[transketolase]’ 1996 Contents of folder so inscribed divided into six for ease of reference: BBSRC grant application, papers for UCL- Exeter-Edinburgh-Liverpool Collaborative Group 4th Annual Research Meeting, 6 December 1996. Bioconversion. C.460-C.472 Patents 1990-1994 See also C.943. C.460-C.471 ‘Patent’s application’ and ‘Image Analysis (Protection) 1990-1993 Contents of folder so inscribed divided into twelve for ease of reference: correspondence and papers re patenting biomass image analysis system. At C.471 are the contents of a plastic folder found inside the principal folder. See also C.472. M.D. Lilly NCUACS150/7/06 49 University College London, C.1-C.971 C.472 ‘Colin Thomas - Grants’ 1993-1994 Contents of folder so inscribed: correspondence and papersre patent. See also C.460-C.471. C.473-C.757 TEACHING AND TRAINING 1959-1998 C.473-C.577 ‘Teaching notes’ C.578-C.757 ‘Summer courses’ C.473-C.577 ‘Teaching Notes’ 1959-1998 Contentsof Lilly’s ‘Teaching Notes’ boxes. The dating of muchofthis material is problematic. C.473-C.475 ‘Lecture Notes Philadelphia 1969’ Contents of folder so inscribed divided into three for ease of reference: duplicated manuscript lecture notes ‘The of Content and Enzymes of Microorganisms’, etc. Microorganisms’, Organisation ‘Disruption ‘Production Cells’, by of C.476 untitled notes headed Contents of ‘Preparation of Immobilised Enzymes’, also identified as ‘© Dunnill & Lilly 1970’; ‘Lecture List Enzyme Technology Course, 7-11 September 1970’, etc typescript folder: 1970 Most of the papers in the folder were photocopies of the papers at C.473-C.475, and have not been retained. C.477-C.478 ‘B18 Microbial Product Formation Productivity’ 1959-1970 Contents of folder so inscribed divided into two for ease of reference: and background headed ‘Fermentation in Relation to Enzyme Production’, also manuscript material, typescript including notes notes and_ M.D.Lilly NCUACS150/7/06 50 University College London, C.1-C.971 identified as ‘© Dunnill & Lilly 1970’. C.479 ‘Biochemical Reactors’ 1971-1972 Photocopied pages of figures for Lecture Courses on Fermentation Biochemical Engineering. Technology M.Sc. for in C.480 ‘E 830 Anaerobic Fermentations’ N.d. Contents background material. of folder so inscribed: manuscript notes, Latest bibliographical reference, 1971. C.481 ‘E 830 Introduction to Fermentation Technology’ N.d. of Contents folder background material. 1981. so inscribed: notes, Latest bibliographical reference, manuscript C.482-C.485 ‘Design Projects’ 1974-1979 Contents of folder so inscribed divided into four for ease of reference: manuscript notes and drafts, etc. Includes photocopied manuscript ‘Chapter 3 Medium sterilization’ paginated 8-42 and ‘Chapter 5 The fermentors design’. C.486 ‘Introduction to Fermentation Design’ Contents of folder so inscribed: manuscript and typescript notes. Latest date in notes ‘17/9/76’. C.487 ‘Fermentation Kinetics (Batch)’ Contents of folder so inscribed: figures, manuscript notes, etc. Latest bibliographical reference 1981. N.d. N.d. M.D.Lilly NCUACS150/7/06 51 University College London, C.1-C.971 C.488 ‘M.Sc. Design Project 1982’ 1981-1982 Contents of folder so inscribed: manuscript notes, letter, 14 November 1981. C.489-C.492 ‘Course in Biochemical Engineering’ 1982-1984 Contents of ring binder so titled divided into four for ease of reference: course outlines, tutorial and examination arrangements, notes for research students, safety regulations,etc. timetables, C.493-C.495 ‘Lecture Notes’ Contents of folder so inscribed divided into three for ease of reference: papers for overhead projections including transparencies, of Fermentation Process’, ‘Penicillins’, etc. ‘Fermentation Products’, ‘Types Latest bibliographical reference 1986. C.496-C.497 Contents of untitled folder divided into two for ease of reference: manuscript notes, figures, product literature, background papers Latest bibliographical reference, 1987. N.d. N.d. C.498 Contents of untitled folder: references, figures, notes etc re sterilisation 1987, 1993 C.499-C.507 ‘Lecture Notes’ 1988-1996 Contents of folder so inscribed divided into nine for ease of reference, manuscript and typescript notes and drafts, figures, background papers, etc., re fermentation, scale- up, etc. C.508 Contents of untitled folder: manuscript notes, figures for lectures on ? fermentation technology N.d. Includes manuscript notes headed ‘B18 - Lecture 4’. Latest bibliographical reference 1989. M.D.Lilly NCUACS150/7/06 52 University College London, C.1-C.971 C.509-C.512 Contents of untitled binder divided into four for ease of reference: lecture course or courses, October - December 1989, November 1990 and October-November 1993 manuscript notes (photocopies) for 1989-1993 There is no general heading for the 1989 lectures (C.509, C.510). Titles of individual lectures include ‘Enzyme Systems’, ‘Reactor Systems with Microorganisms’, ‘Costs of fermentation’, ‘Continuous culture’, etc. 1990 (C.511) are lectures The ‘Process Development’ and the 1993 lectures (C.512) are headed ‘Biochem. Eng. Fermentation’. headed C.513-C.514 ‘Teaching’ 1990-1993 Contents of folder so inscribed divided into two for ease of reference: drafts, correspondence, lecturelists. manuscript typescript notes, Includes material re course planning including courses given by Department of Biochemistry for biochemical engineers. C.515 ‘Departmental Lecture Notes’ 1991-1996 Contents manuscript typescript drafts, correspondence, lecturelists, etc. folder so inscribed: of notes, Includes material re course planning. C.516 ‘Industrial Visits’ 1991-1995 Contents of folder so inscribed: correspondence with industrial colleagues, internal memos, etc. C.517 ‘Industrial Fermentation Notes’ Contents of folder so inscribed: manuscript notes. C.518 ‘E839 Contents of folder so inscribed: includes typescript notes, lecturelists, figures, etc. 1993 1995 M.D.Lilly NCUACS150/7/06 53 University College London, C.1-C.971 Mostof the material is undated. C.519, C.520 ‘Introduction to Biochemical Engineering E839 and B.28 (part 1) courses’ 1995 Typescript notes re lecture courses. The lecturers were UCL colleagues Keshavarz-Moore andLilly. P. Dunnill, E. Twofolders. C.521-C.529 ‘Lecture Notes’ 1995-1997 Contents of folder so inscribed divided into nine for ease of reference: typescript notes,figures, etc. Titles ‘Fermentation Scale-up’, ‘Fermentation Sterilisation’, etc. ‘Fermentation include Process Development’, C.530-C.547 Integrated Graduate Development Scheme (IGDS) for Bioprocessing Module 2 Fermentation, Advanced Centre for Biochemical Engineering, UCL 1993-1996 The scheme was sponsored by the Biotechnology and Biological Science Research Council within a scheme operated the Science Research Council. Engineering and Physical by C.530-C.534 ‘Fermentation’ 1994 Contents of ring binder so labelled divided into five for ease of reference: daily programmes, course notes. delegates list, This was ‘Module 2: Integrated Graduate Development Schemefor Bioprocessing’, October 1994-January 1995. C.535, C.536 ‘IGDS - Fermentation Module’ 1993-1995 Contents of folder so inscribed divided into two for ease of reference: includes papers re course preparation, IGDS programmebrochure and course feedback. M.D.Lilly NCUACS150/7/06 54 University College London, C.1-C.971 C.537-C.538 ‘Fermentation Kinetics’ 1994-1996 Contents of folder so inscribed divided into two for ease of reference: includes papers re fermentation case study. C.539-C.541 ‘IGDS - BT Module’ 1994-1995 reference: Contents of folder so inscribed divided into three for ease re mock exam questions, of practicals, 3 Biotransformations’. etc study Module drafts case for ‘IGDS C.542 ‘IGDS -BT Module’ 1995-1996 Contents of folder so inscribed: catalysts, biocatalytic reactors. drafts re immobilized C.543-C.547 ‘New MSc Coursein Bioprocessing (IGDS)’ 1993 Contents of folder so labelled divided into five for ease of reference: course administration. correspondence papers and re C.548 C.548A A Hands-on Course on Scaling up Technology’, Advanced Centre for Biochemical Engineering, UCL, 11-15 April 1994 Course notes ‘Biochemical Engineering Practical Course for the Institute of Biochemical Engineering, UCL, 25-29 April 1994 Biotechnology’, Advanced Centre for Course notes. 1994 1994 C.549-C.552 Modular Training for the BioprocessIndustries 1995, 1997 Training courses delivered by the Advanced Centre for Biochemical Engineering at UCL. Lilly contributed to the teaching. M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.549 ‘Fermentation’ Contents of ring binder so labelled. This was ‘Book1 of 2’. In original binder. Table of contents, daily programme, course notes,etc. C.549A ‘Fermentation’ Contents of ring binder so labelled. This was ‘Book2 of 2’. In original binder. Table of contents, daily programme, course notes,etc. 55 1995 1995 C.550 ‘Principles of Fermentation Processes’ 1997 Contents of ring binder so labelled. In original binder. Delegate profiles, course notes, etc. section contents, daily programme, C.551 ‘Fermentation Biology/Engineering Interface’ Design and Scale-up il The 1997 Contents of ring binder so labelled. In original binder. Section contents, daily programme, course notes, case studies, etc. C.552 ‘Fermentation Process Operation’ 1997 Contents of ring binder so labelled. In original binder. Section contents, daily programme, course notes, case studies, etc. M.D.Lilly NCUACS150/7/06 56 University College London, C.1-C.971 C.553-C.555 Undated notes and drafts C.553 ‘Enzyme Reactor Kinetics’ Contents of folder so inscribed. C.554 ‘Biochemical Reactors’ Contents of folder so inscribed. C.555 ‘Fermentation Culture E818’ Kinetics (Continuous)’ and ‘Continuous Contents of folder so inscribed. C.556-C.577 Miscellaneous correspondence and papers re teaching andtraining. 1960s -1998 Many papersfound loose. 22 folders. At C.563-C.566 are papers re undergraduate course structure Biochemical Engineering, 1984. 4-year BEng course and in At C.574, C.575 is background material etc re Thames Water sewage treatment etc. At C.576, C.577 is background material re biochemical engineering coursesat otherinstitutions. C.578-C.757 ‘Summer Courses’ 1967-1996 ContentsofLilly’s ‘Summer Courses’ boxes. These courses were given by UCL staff including Lilly and others for participants from industry and academe, many from overseas. C.578-C.680 ‘Course in Biochemical Engineering’ 1979-1991 Contents of ring binders so labelled: course documentation M.D.Lilly NCUACS150/7/06 57 University College London, C.1-C.971 including programme,list of participants, lecture notesetc. C.578-C.582 ‘Advanced Biochemical Engineering Course (No.3)’ 1979 Five folders. C.583-C.588 ‘Biochemical Engineering Course (no.4)’ 1980 Six folders C.589-C.595 ‘Biochemical Engineering SummerCourse (No.5’) 1981 Sevenfolders. C.596-C.602 ‘Biochemical Engineering Course(6)’ 1982 Sevenfolders. C.603-C.610 Biochemical Engineering Summer Course (No.7)’ 1983 Eight folders. C.611-C.618 ‘Biochemical Engineering Summer Course (No.8)’ 1984 Eightfolders. C.619-C.626 ‘Biochemical Engineering SummerCourse (No.9)’ 1985 Eight folders. C.627-C.635 ‘Biochemical Engineering SummerCourse (No.10)’ 1986 Nine folders C.636-C.644 ‘Biochemical Engineering SummerCourse (No.11)’ 1987 Nine folders. M.D.Lilly NCUACS150/7/06 58 University College London, C.1-C.971 C.645-C.653 ‘Biochemical Engineering SummerCourse (No.12) ’ 1988 Nine folders. C.654-C.661 ‘Biochemical Engineering SummerCourse (No.13)’ 1989 Eight folders. C.662-C.670 ‘Biochemical Engineering SummerCourse (No.14)’ 1990 Nine folders. C.671-C.680 ‘Biochemical Engineering SummerCourse (No.15)’ 1991 Ten folders. C.681-C.757 Miscellaneous correspondence and papers re summer courses 1970-1996 C.681-C.685 ‘Enzyme Technology Course’ 1970 Lecture list, course, 7-11 September 1970, found tagged together. list of participants, lecture notes, etc for Five folders. C.686-C.687 ‘Biochemical Miscellaneous’ Engineering Course: Pre-1981 1977-1981 Contents of folder so inscribed divided into two for ease of reference:lists of participants, accounts etc. C.688-C.692 ‘All correspondence’ 1978 correspondence Contents of folder so inscribed divided into five for ease of reference: FEBS [Federation of European Biochemical Societies] Advanced Course No.55 ‘Biochemical Engineering: the Translation of Industrial Processes’, 11-13 September 1978. Biochemistry papers re and and Microbiology and M.D.Lilly NCUACS150/7/06 59 University College London, C.1-C.971 C.693-C.707 ‘SummerCourse Notes / Old Notes & Drawings’ 1973-1979 Contents of box folder so inscribed divided into fifteen for ease of reference: includes course notes for ? Advanced Biochemical Engineering Course, 10-14 September 1979, a copy of the programmeof whichis at C.695. At C.702 is copy of ‘Biochemical Reactors’, Lilly's Plenary Lecture, Achema Congress, Frankfurt, 1973 and at C.704 a copy of ‘Developments in Biocatalysis’, Lilly's Plenary Lecture at Achema Congress, 22 June 1979. The papers at C.706 were found in a folder inscribed ‘Malcolm Lilly’ and the papers at C.707in a folder inscribed ‘Methodsin Enzymology’. C.708-C.710 ‘BESC 1983 Course Admin’ 1982-1983 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re arrangements including course questionnaires for 1982 and 1983. C.711-C.714 ‘BESC 1983 Course Enquiries’ 1982-1983 Contents of folder so inscribed: includes registrations. C.715 ‘BESC 1983 Masters’ 1983 Contents of folder so inscribed: information for speakers, participants etc. C.716-C.720 ‘BESC 1984 Admin’ 1983-1985 Contents of folder so inscribed divided into five for ease of reference: includes course questionnaires. C.721-C.723 Course notes 1984 Three folders. C.724-C.727 ‘Summer course’ 1984-1988 M.D.Lilly NCUACS150/7/06 60 University College London, C.1-C.971 Contents of folder so inscribed divided into four for ease of reference: transparencies, manuscript notes and programmes for 1984 and 1985 meetings. including course notes’ C.728-C.729 ‘Biochemical Engineering SummerCourse’ 1985, 1987 Contents of folder so inscribed divided into two for ease of reference: photocopied manuscript ? course notes. C.730 ‘BE Short Course’ 1988-1989 Contents of folder so inscribed: annotated course notes, etc. C.731-C.733 ‘BESC 1988’ 1987-1988 Contents of folder so inscribed divided into three for ease of reference. C.734-C.735 ‘BESC 1989’ 1988-1989 Contents of folder so inscribed divided into two for ease of reference: includes course questionnaires. C.736-C.737 ‘BESC 1990’ 1989-1990 Contents of folder so inscribed divided into two for ease of reference: includes course questionnaires. C.738 ‘Lecture notes 14th Biochemical Engineering Summer Course (1990)’ 1990 6pp typescript + figures. C.739-C.740 ‘BESC 1991’ 1990-1991 Contents of folder so inscribed divided into two for ease of reference: includes course questionnaires. M.D.Lilly NCUACS150/7/06 61 University College London, C.1-C.971 C.741-C.742 Course notes ? 1991 Typescript notes, some annotated; transparencies etc ? for 1991 course. manuscript notes; Twofolders. C.743 ‘International Course 1992’ 1991-1992 Contents of folder so inscribed: correspondence and papers re arrangements. The course was cancelled because there were not enough applicants to coverthe costs. C.744-C.750 Miscellaneous course notes 1967-1996 Papers found looseorin unidentified folders. Seven folders. C.751-C.754 ‘Teachers Conference’ 1986-1995 Contents of folder so inscribed divided into four for ease of reference: programmes, lists of participants, course notes etc for INSET Seminars on Biochemical Engineering and the Biotechnology-Based Industries. Papers found with summer course material. C.755-C.757 Seminars Correspondence Biochemical Engineering and the Biotechnology-Based Industries papers and re INSET 1990-1992 Papers found with summercourse material. Principally course questionnaires. Three folders. M.D.Lilly NCUACS150/7/06 62 University College London, C.1-C.971 C.758-C.891 PERSONNEL 1964-2002 An alphabetical sequence of Lilly's ‘personnel’ files departmental visitors, research students, etc re Includes arrangements to career. visit, research, publications, C.758 C.759 Bal. C.760-C.761 Bar. Twofolders. C.762 C.763 Bla. Bri. C.764-C.768 Bro. (1) Five folders. C.769 Bro. (2) C.770-C.774 Bu. C.770 1973-1974 C.771 1975-1976 1980-1989 1971-1981 1995-1997 1992-1994 1970-1971 1998 1979-1984 1973-1996 M.D.Lilly NCUACS150/7/06 63 University College London, C.1-C.971 C.772 1977-1978 C.773 1979-1980 C.774 1989-1996 C.775 C.776 C.777 C.778 Car. Cas. Cav. Che. Letter, 26 June 2002, is from Sheila Lilly. C.779 Chu. C.780-C.782 Co. Three folders. C.783 C.784 Cu. Dal. C.785, C.786 Das. 2 folders. 1972-1977 1991 1992 1974-2002 1974 1994 1988-1994 1973-1974 1970-1973 M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.787-C.789 Der. 3 folders. C.790 C.791 C.792 C.793-C.795 Dun. Duv. Fi. Fr. C.793 1983-1985 C.794 1986-1987 C.795 1991-1996 1988-1991 N.d. 1974-1979 1964-1976 1983-1996 C.796-C.799 Gr. 1969-1987 C.796 1969-1970 C.797 1971-1974 C.798 1975-1980 C.799 1987 C.800 Hac. 1990-1991 M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.801 C.802 Hai Hal. C.803-C.804 Har. 2 folders. C.805 Hi. C.806-C.811 Hob. 65 1983-1984 1975 1967-1973 1972-1975 1991-1994 Muchof the material was undated and the arrangementis tentative. Six folders. C.812-C.814 Hu. 1972-1976 C.812 1972-1973 C.813 1974-1975 C.814 1973-1976 C.815 C.816-C.822 Ja. Jo. C.816 1988-1991 1972-1974 1988-1995 M.D.Lilly NCUACS150/7/06 66 University College London, C.1-C.971 C.817-C.818 1991 Twofolders. C.819-C.821 1992 Threefolders. C.822 1993-1995 C.823 Kap. C.824 C.825 C.826 C.827 Kay Ke. Kl. Kr. C.828-C.829 La. C.828 1972-1973 C.829 1974-1975 C.830 C.831 Lil. Lim. 1972, 1976 1968-1972 1985-1988 1981-1984 1971 1972-1975 1983 1974-1975 M.D.Lilly NCUACS 150/7/06 University College London, C.1-C.971 C.832 C.833 Mac. Mar. C.834-C.835 Mat. Twofolders. C.836 C.837 Mos. Ny. C.838-C.840 Ola. C.838 1975 C.839 1976-1980 C.840 1993-1994 C.841 O’Ne C.842-C.847 Pac. Six folders C.848 C.849 Pal. Par. 67 1970-1975 1991-1992 1991-1995 1972-1975 1968 1975-1994 1968, 1972 1989-1992 1984-1985 1976-1986 M.D.Lilly NCUACS 150/7/06 68 University College London, C.1-C.971 C.850-C.851 Reg. 1970-1975 C.850 1970-1971 C.851 1972-1975 C.852 Rich. C.853 Rick. C.854 C.855 C.856 C.857 Rob. Ros. Rus. Sen. C.858 | Sha. C.859 C.860 C.861 Shr. Sto. Str. C.862-C.865 Su. Four folders. 1973-1974 1971 1969-1974 1992-1994 1986-1992 1978-1979 1968 1988-1991 1995-1996 1972-1973 1989 M.D.Lilly NCUACS150/7/06 University College London, C.1-C.971 C.866 Tim. C.867-C.870 Var. Four folders. C.871 Vil. C.872 War. (1) C.873-C.874 War.(2) Twofolders. C.875 Wh. C.876 C.877-C.882 Wo. Six folders. C.883 C.884-C.885 Wy. C.884 1970-1973 C.885 1974 69 1970 1978-1982 1976-1983 1971-1976 1989-1992 1971-1976 1967-1968 1988-1998 1989-1990 1970-1974 C.886-C.891 Yu. 1989-1991 M.D.Lilly NCUACS 150/7/06 70 University College London, C.1-C.971 C.886 1989-1991 C.887-C.889 1991 Three folders. C.890-C.891 N.d. Twofolders. C.892-C.971 MISCELLANEOUS 1966-1997 C.892-C.965 Topics C.966-C.971 Shorter correspondence and papers C.892-C.965 Topics C.892-C.894 Annual Lecture 1966-1997 1990-1996 Correspondence and papers re arrangements for Annual Lecture of the Centre for Biochemical Engineering and Biotechnology. Threefolders. C.895-C.905 Biotechnology Computer Systems Ltd (BCS) 1984-1990 Correspondence and papersre joint project between BCS and UCL for the development of ‘a “state-of-the-art” computer-based data-logging and control system for biological reactors’ (C.902), etc. Eleven folders. C.906-C.907 Bursaries 1988-1996 M.D.Lilly NCUACS150/7/06 71 University College London, C.1-C.971 Correspondence and papers re departmental bursaries administered byLilly. Twofolders. C.908-C.912 ‘Centre for Biotechnology Architects Drawings’ and ‘Foster Court’ 1982-1984 Contents of folder so inscribed divided into five for ease of reference. C.913 ‘Equipmentfor Old Pilot Plant’ 1981, n.d. Contents of folder so inscribed: includes‘Initial study into the upgrade of the Pilot Project and Control Laboratory and the developmentof a 21st [?century] Training Facility’, n.d. C.914-C.929 ‘Fermenter Drawings’ 1966-1987 Contents of folder so inscribed divided into sixteen for ease of reference: includes productliterature. C.930-C.941 Link Programme 1990-1995 This was a research programmeat UCL in association with Biological SmithKline Beecham Pharmaceuticals, Products, the Departmentof Trade and Industry and SERC. Research, Shell ICI Unilever Research, See also C.236-C.304. C.930-C.932 ‘Link Grant’ 1990-1995 Contents of folder so inscribed divided into three for ease of research partners and papersfor presentation. includes correspondence with reference: C.933-C.941 Progress Reports C.933 Progress Report No.1 for liaison meeting at UCL on 16th November 1990 1990-1994 1990 M.D.Lilly NCUACS150/7/06 C.934 C.935 C.936 C.937 C.938 C.939 C.940 University College London, C.1-C.971 Progress Report No.2 for liaison meeting at UCL on 8th May 1991 Progress Report No.3 for liaison meeting at the Shell Centre on 14th November 1991 Progress Report No.4 for liaison meeting at Unilever House on 8th May 1992 Progress Report No.5 forliaison meeting at Warren House on 6th November 1992 Progress Report No.6 for liaison meeting at New Horizons Court on 7th May 1993 Progress Report No.7 for liaison meeting at UCL on 11th November 1993 Progress Report No.8 for liaison meeting at UCL on 7th April 1994 C.941 Progress Report No.9 72 1991 1991 1992 1992 1993 1993 1994 N.d. C.942 ‘Old Pilot Plant Re-opening’ 1979-1981 Contents of folder so inscribed: alterations and re-opening, 2 June 1981. includes papers re C.943 ‘Patents’ 1971-1991 Contents of folder so inscribed: includes correspondence and patent specifications. See also C.460-C.472. M.D.Lilly NCUACS150/7/06 73 University College London, C.1-C.971 C.944-C.946 ‘PhD / RA Notes’ 1982-1997 Contents of folder so inscribed divided into three for ease of grant application, etc. reference: research results, thesis reports, C.947-C.948 ‘Provost’ 1980-1986 Contents of folder so inscribed: correspondence with UCL Provost, Sir James Lighthill. C.947 1980-1981 C.948 1985-1986 C.949-C.950 ‘Provost’s Advisory Group on Bioengineering’ 1992, 1996 Contents of folder so inscribed divided into two for ease of reference: includes papers for Biotransformation Research Advisory Group. C.951 ‘Scale Up Review + SB [Smithkline Beecham]‘ 1991-1996 Contents of folder so inscribed: principally re UCL / Smithkline Beecham collaboration on Fermentation Scale- up. C.952-C.954 ‘SERC Centre’ 1986-1989 Contents of folder so inscribed divided into three for ease of reference. At C.952 is the UCL Department of Chemical and Biochemical Engineering ‘Response to the Biochemical Engineering Biotechnology Directorate’, latest bibliographical reference 1986. the SERC Initiative of See also C.23. M.D.Lilly NCUACS150/7/06 74 University College London, C.1-C.971 C.955-C.963A ‘TAU [Tel Aviv University] Collaboration’ 1983-1997 Contents of folder so inscribed: correspondence and papers re between UCL and Tel-Aviv University. collaboration include E. Katzir-Katchalski and A. Correspondents Freeman. See also H.59A. C.955 1983 Includes programmefor conference on ‘Achievements and Expected Tel-Aviv University, 7-9 June 1983. Lilly talked on immobilized biocatalysts in a session on industrial applications. Biotechnology’, Developments in C.956 C.957 C.958 1991 1992 1993 C.959-C.960 1994 Twofolders. Includes application for a joint UK-lsrael Research Grant (C.960). C.961 C.962 C.963 1995 1996 1997 C.963A N.d. M.D.Lilly NCUACS150/7/06 75 University College London, C.1-C.971 C.964 ‘Visitors to UCLbe’ 1991, 1993 Contents of arrangements, letters of thanks. folder so inscribed: correspondence re 1993 papers relate to visit from Wageningen Agricultural University, The Netherlands. C.965 ‘Wolfson Application’ 1992 Contents of folder so inscribed: papers relate to proposed new researchlaboratory for process engineering. C.966-C.971 Shorter correspondence and papers 1973-1994 C.966 1973 C.967 1984-1985 C.968 1987-1990 C.969 1991 C.970 1992-1996 C.971 N.d. M.D.Lilly NCUACS150/7/06 76 SECTION D PUBLICATIONS, D.1-D.366 1962-2003 D.1-D.361A OWNPUBLICATIONS D.362-D.366 PUBLICATIONS CORRESPONDENCE D.1-D.361A OWN PUBLICATIONS 1962-2003 D.1 D.2 D.3 D.4-D.5 The numbering of the papers correspondswith that in the bibliography at A.2. (1) 1962 Cell wall precursors in Escherichia coli 26-26. J. Gen. Microbiol. 28, ii-iii. 1962 Typescript draft and off-print. (2) 1962 (With P.H. Clarke) A general structure for cell walls of Gram-negative bacteria. Nature 195, 516-517 Off-print only. (3) 1963 (With P.H. Clarke and P.M. Meadow) The accumulation of nucleotides by Escherichia coli strain 26- 26. J. Gen. Microbiol. 32,103-116 Contents of Lilly’s folder: off-print, drafts, correspondence. (4) 1965 (With R.J. Ertola and F.C. Webb) Production of cell microbiological process. Biotechnol. Bioeng. 7, 309-319 hydrocarbons tissue from by a_ 1962 1963 1964-1965 Contents of Lilly's folder divided into two for ease of reference: manuscript and typescript drafts. correspondence, off-print, D.6 (5) 1965 (With W. Hornby, C. Money and E.M. Crook) Enzymesonsolid supports. Biochem J. 95, 45-46P 1965 ContentsofLilly’s folder: off-print, letter from co-author. M.D.Lilly NCUACS150/7/06 77 Publications, D.1-D.366 D.7-D.8 (6) 1965 Extraction and separation of nucleotides from Escherichia coli. Biotechnol. Bioeng. 7, 335-342 1959-1965 Contents of Lilly’s folder divided into two for ease of reference: off-prints of Lilly’s paper and related papers by others, draft, data, etc D.9 D.10 (7) 1966 (With L.P. Hadjipetrou and T. Gray-Young) Effects by Escherichia coli. J. Gen. Microbiol. 45, 479-488 ferricyanide production energy on of Contents ofLilly’s folder: off-print, draft (8) 1966 (With W.E. Hornby and E.M. Crook) The preparation and properties of ficin chemically attached to carboxymethyl cellulose. Biochem J. 98, 420-425 ContentsofLilly’s folder: off-print, draft. 1966 1966 D.11-D.15 (9) 1966 (With W.E. Hornby and E.M. Crook) Thekinetics of carboxymethylcellulose-ficin in packed beds. Biochem J. 100, 718-723. 1966, 1976 Contents of Lilly's folder divided into five for ease of reference:off-print, drafts, correspondenceetc. D.16-D.17 (10) 1966 (With A. Boddy and P.H. Clarke) Periodic changes Pseudomonas aeruginosa in continuous culture. J. Gen. Microbiol. 45, ii- ili. synthesis amidase by in 1966-1967 Contents of Lilly's folder divided into two for ease of reference: photocopy of paper and offprint of later (1967) related paper, correspondence, manuscript notes, figures. D.18 (11) 1966 (With T. Gray Young and L.P. Hadjipetrou) The theoretical aspects of biochemical fuel cells. Biotechnol. Bioeng. 8, 581-593. 1966 ContentsofLilly's folder: off-print, drafts. D.19-D.20 (12) 1967 (With T.K.N. Baidya and F.C. Webb) The 1966-1967 M.D.Lilly NCUACS150/7/06 D.21 D.22 D.23 D.24 D.25-D.26 Publications, D.1-D.366 utilization of mixed sugars in continuous fermentation. Biotechnol. Bioeng. 9, 195-204 Contents of Lilly's folder divided into two for ease of reference: off-print, drafts, manuscript notes, figures, etc. (13) 1967 (With P. Dunnill, P.M. Dunnill, A. Boddy and M. Houldsworth) The large scale isolation of prolyl-tRNA synthetase from Phaseolus aureus. Biotechnol. Bioeng. 9, 343-356 ContentsofLilly’s folder: off-print, draft. (14) 1967 (With D.S. Flynn) A methodfor the control of the dissolved oxygentension in microbial cultures. Biotechnol. Bioeng. 9, 515-531. Off-print only. (15) 1967 (With D.S. Flynn, D.G. Kilburn and F.C. Webb) Modifications electrode. Biotechnol. Bioeng. 9, 623-625 Mackereth oxygen. the to 78 1967 1967 1967 Off-print only. (16) 1967 Enzyme synthesis in micro-organisms. Process Biochem.2, February, 17-21 1965-1967 ContentsofLilly's folder: off-print, correspondence,drafts. 1967 (With A. Boddy, P.H. Clarke and M.A. (17) Houldsworth) by Pseudomonas aeruginosa 8602 in continuous culture. J. Gen. Microbiol. 4S. 137-145 Regulation synthesis amidase of 1967 Contents of Lilly’s folder divided into two for ease of reference: proof, drafts D.27-D.28 (18) 1967 (With P. enzymes. Process Biochem. 2, July, 13-15 Dunnill) Large scale isolation of 1967 Contents of two folders of Lilly's, one inscribed with the title of the paper and the second inscribed ‘1967 (Process M.D.Lilly NCUACS150/7/06 79 Publications, D.1-D.366 Large off-print, Biochem) correspondence,drafts, manuscript notes, duplicated and printed background material. (General): scale (19) 1968 (With W.E. Hornby and E.M. Crook) Some changes in the reactivity of enzymes resulting from their chemical attachment to water-insoluble derivatives of cellulose. Biochem J. 107, 669-674 1966-1968 ContentsofLilly’s folder: off-print, drafts, correspondence. (20) 1968 (with G. Kay, A.K. Sharp and R.J.H. Wilson) Preparation and use of porous sheets with enzymeaction. Nature 217, 641-642 Contentsof Lilly’s folder: off-print, proof, correspondence. (21) 1968 (With P .H. Clarke and M.A. Houldsworth) of amidase Catabolite synthesis in continuous culture. J. Gen. Microbiol. 51, 225-234 repression and the by induction aeruginosa Pseudomonas 8602 Contents of Lilly’s folder: off-print only. (22) 1968 (With G. Kay, A.K. Sharp and R.J.H. Wilson) The operation fixed enzymes. Biochem. J., 107, 5P biochemical reactors using of Contents ofLilly’s folder: off-print, drafts, letter from E.M. Crook. (23) 1968 (With A.K. Sharp) The kinetics of enzymes attached to The Chemical Engineer 215, 12-18. water-insoluble polymers. Contents of Lilly's folder divided into five for ease of reference: off-print, correspondence, drafts, comments of the referees, figures. 1968 (With and (24) Kay) The preparation dehydrogenase attached to water-insoluble particles and sheets. Biochem J. 108, 845-853 R.J.H. Wilson and G. kinetics lactate of 1968 1968 1967-1968 1967-1968, 1978 1968 D.29 D.30 D.31 D.32 D.33-D.37 D.38 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.39 D.40 Contents ofLilly’s folder: off-print, draft, figures. (25) 1968 (With R.J.H. Wilson) The kinetics of a novel cyclic reaction system and its use in the assay of polynucleotide phosphorylase or adenosine diphosphate plus adenosine triphosphate. Biochem J. 108, 887-895 Contentsof Lilly’s folder: off-print, draft. 1968 (With R.J.H. Wilson and G. (26) Kay) The preparation and properties of pyruvate kinase attached to porous sheets, and the operation of a two-enzyme continuous-feed reactor. Biochem J. 109, 137-141 ContentsofLilly's folder: off-print, draft. D.41-D.44 (27) 1968 (With D.A. Self and D.G. Kilburn) The influence of dissolved oxygen partial pressure on the level of various enzymes in mouse LScells. Biotechnol. Bioeng. 10, 815-828 80 1968 1968 1968 Contents of Lilly’s folder divided into four for ease of reference: off-print, figures, manuscript working. correspondence, drafts, D.45 (28) 1968 (With P. Dunnill, R.A. Fisher, H. Harris and M. Houldsworth) Large-scale isolation of acid phosphatase from human erythrocytes. Biotechnol. Bioeng. 10, 829-843 1968 ContentsofLilly’s folder: off-print, draft, figures. D.46-D.47 (29) 1969 (With D.G. Kilburn, D.A. Self and F.C. Webb) The effect of dissolved oxygen partial pressure on the growth and carbohydrate metabolism of mouse LS cells. J. Cell. Sci. 4, 25-37 1968-1969 Contents of Lilly's folder divided into two for ease of reference: report, drafts. correspondence, referee’s off-print, D.48-D.49 (30) 1969 (With P.H. Clarke) The regulation of enzyme synthesis during growth. X/Xth Symp. Soc. Gen. Microbiol. 1967-1969 M.D.Lilly NCUACS150/7/06 D.50 D.51 D.52-D.53 Publications, D.1-D.366 (ed. P.M. Meadow and S.J. Pirt), pp. 113-159. Cambridge: University Press Contents of Lilly’s folder divided into two for ease of reference: off-print, correspondence,draft, data. (31) 1969 (With P. Dunnill) Enzymes: a new technology. Science Journal April, 59-63 Off-print and duplicated typescript. (32) 1969 (With P.H. Clarke, M. Houldsworth, J.A. Currie and P. Dunnill) The isolation of an aliphatic amidase from Pseudomonas aeruginosa. Biotechnol. Bioeng. 11, 283- 292 Contents ofLilly’s folder: off-print, drafts. (33) 1969 (With D.A. Self and G. Kay) The conversion of benzyl penicillin to 6-amino-penicillanic acid using an derivative insoluble penicillin amidase. Biotechnol. Bioeng. 11, 337-348 of Contents of Lilly's folder divided into two for ease of reference: off-print, drafts, figures etc. D.54 (34) 1969 (With R.J.H. Wilson) Preparation and use of insolubilised amyloglucosidase for the production of sweet glucoseliquors. Biotechnol. Bioeng. 11, 349-362 ContentsofLilly's folder: off-print, draft, figures. D.55-D.56 D.57-D.59 (35) 1969 (With A.K. Sharp and G. Kay) Thekinetics of B- galactosidase sheets. Biotechnol. Bioeng. 11, 363-380 cellulose attached porous to Contents of Lilly’s folder divided into two for ease of reference:off-print, drafts, figures. P. (36) 1969 (With of intracellular enzymes from micro-organisms - the development of a continuous process. In Fermentation Advances (ed. D Perlman), pp. 225-247. New York: Academic Press Isolation Dunnill) 81 1969 1969 1969 1969 1969 1969 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.60 D.61 D.62-D.63 D.64 D.65-D.70 Contents of Lilly’s folder divided into three for ease of reference: off-print, drafts. (37) 1969 (With D.G. Kilburn and F.C. Webb) The energetics of mammalian cell growth. J. Cell. Sci. 4, 645- 654 Off-print only. (38) 1970 (With G. Kay) The chemical attachment of chymotrypsin to water-insoluble polymers using 2-amino- 4,6 dichloro-s-triazine. Biochim. Biophys. Acta 198, 276- 285 Contents of Lilly’s folder: off-print, draft, figures. (39) 1970 (With P. Dunnill and J.A. Currie) Continuous enzyme prolyl-tRNA synthetase from Phaseolus aureus. Biotechnol. Bioeng. 12, 63-74 processing: isolation the of Contents ofLilly’s folder so inscribed divided into two for easeof reference:off-print, correspondence,drafts. (40) 1970 (With L. Hadjipetrou and. P. Kourounakis) Effect of van Leeuwenhoek 36, 531-540 ferricyanide Escherichia Antonie coli. on Off-print only. (41) 1971 (With P.J. Hetherington, M. Follows and P. Dunnill) yeast (Saccharomyces cerevisiae) by disruption in an industrial homogeniser. Trans. Instn. Chem. Engrs. 142-148 Release bakers protein from of 82 1969 1970 1969-1971 1970 1970-1971 Contents of Lilly’s folder divided into six for ease of reference: off-print, correspondence, drafts, figures, etc. D.71-D.72 (42) 1971 (With J.R. Wykes and P. Dunnill) Conversion of tyrosine to L-dihydroxy-phenylalanine using immobilised tyrosinase. Nature 230, 187 1970-1971 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 Contents of Lilly’s folder divided into two for ease of reference: off-print, drafts, figures, duplicated background papers. (43) 1971 (With S.P. O’Neill, J.R. Wykes and P. Dunnill) An soluble immobilized enzyme. Biotechnol. Bioeng. 13, 319-322. ultrafiltration-reactor system using a_ 83 1970-1971 D.73 D.74-D.75 D.76-D.77 D.78 D.79 D.80 ContentsofLilly’s folder: off-print, correspondence,drafts. (44) 1971 (With S.P. O’Neill and P. Dunnill) A comparative study of immobilised amyloglucosidase in a packed bed reactor and a continuous feed stirred tank reactor. Biotechnol. Bioeng. 13, 337-352 1970-1971 Contents ofLilly's folder so inscribed divided into two for easeof reference: off-print, correspondence, drafts. (45) 1971 (With M. Follows, P.J. Hetherington and P. Dunnill) Release of enzymes from baker's yeast by disruption Biotechnol. Bioeng. 13, 549-560. homogeniser. industrial an_ in Contents of Lilly’s folder divided into two for ease of reference: off-print, correspondence, drafts, figures. (46) 1971 Stability of immobilised, R-galactosidase on prolonged storage. Biotechnol. Bioeng. 13, 589 Contentsof Lilly’s folder: offprint, draft. (47) 1971 (With P.R. Foster and P. Dunnill) Salting-out of enzymes with ammonium sulphate. Biotechnol. Bioeng. 13, 713-718 Contents of Lilly's folder: offprint, letter to journal editor, drafts, figures. (48) 1971 (With S.P. O'Neill and P.N. Rowe) Multiple steady states in continuous flow stirred tank enzyme reactors. Chem. Eng. Sci. 26, 173-175 Contents of Lilly's folder: offprint, drafts, figures etc. 1971 1971 1971 1971 M.D.Lilly NCUACS150/7/06 84 Publications, D.1-D.366 D.81-D.84 (49) 1971 (With P. Dunnill) Biochemical reactors. Process Biochem.6, 29-32 1971 D.85 D.86 Contents of Lilly’s folder divided into four for ease of reference: offprint, correspondence, notes and drafts (50) 1971 (With P. Dunnill) The problems of large-scale extraction and purification of microbial enzymes.J. Gen. Microbiol. 65, ix Offprint only. (51) 1971 (With P.J. Robinson and P. Dunnill) Porous glass as a solid support for immobilisation or affinity chromatography of enzymes. Biochim. Biophys. Acta 242,659-661 Contents ofLilly’s folder: offprint, correspondence,draft D.87-D.88 (52) 1971 (With J.R. Wykes and P. Dunnill) Immobilisation of a-amylase by attachment to soluble support materials. Biochim. Biophys. Acta 250, 522-529. Contents of Lilly's folder divided into two for ease of reference: offprint, drafts. D.89 D.90-D.91 (53) 1972 (With K. Balasingham, D. Warburton and P. Dunnill) The isolation and kinetics of penicillin amidase from Escherichia coli. Biochim. Biophys. Acta 276, 250- 256. Contents of Lilly’s folder: offprint, correspondence. (54) 1972 (With P.J. Robinson and P. Dunnill) Factors affecting R- galactosidase. Biochim. Biophys. Acta 282,28-35 affinity chromatography of scale-up of 1971 1971 1971 1972 1972 Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence,drafts,etc. D.92-D.93 (55) 1972 (With D. Warburton, K. Balasingham and P. Dunnill) The preparation and kinetics of immobilised 1972 M.D.Lilly NCUACS150/7/06 D.94 D.95-D.98 Publications, D.1-D.366 penicillin amidase from Escherichia coli. Biochim. Biophys. Acta 284, 278-284 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. 1972 (With Dunnill) The (56) weight NAD preparation derivative active as a cofactor. Biochim. Biophys. Acta 286, 260-268 J.R. Wykes and P. molecular high of soluble Contentsof Lilly’s folder: offprint, correspondence, draft. (57) 1972 (With J.A. Currie and P. Dunnill) Release of protein from bakers’ yeast, Saccharomycescerevisiae by disruption in an industrial agitator mill. Biotechnol. Bioeng. 14, 725-736 Contents of Lilly’s folder divided into four for ease of reference: offprint, drafts. 85 1972-1973 1972 D.99-D.100 (58) 1972 (With P. Dunnill) Continuous enzyme isolation. Biotechnol. Bioeng. Symp. 3, 97-113 1972 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. D.101 D.102 D.103 (59) 1972 (With enzyme reactors. Biotechnol. Bioeng. Symp. 3, 221-227 Dunnill) Engineering aspects of P. ContentsofLilly’s folder: offprint, correspondence, drafts. (60) 1972 (With P.P. Gray and P. Dunnill) Kinetics of R- galactosidase production by a constitutive mutant of Escherichia coli. J. Ferment. Technol. 50, 381-387 Contentsof Lilly’s folder: offprint, draft, etc. (61) 1972 The use of immobilised enzymesin reactors. Proc. Conf. on Solid Phase Proteins. pp. 75-77. Seattle: Batelle Institute Offprint only. 1971-1972 1972 1972 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.104 D.105 D.106 D.107 D.108 D.109 (62) 1972 (With P.P. Gray and P. Dunnill) The continuous- flow isolation of enzymes. Proc. IV I.F.S. Conf. pp. 347 - 351. Japan: Society of Fermentation Technology Contents ofLilly’s folder: off-print, correspondence,drafts. (63) 1972 (With K. Balasingham, D. Warburton and P. Dunnill) Immobilised enzyme reactors. Proc. IV I.F.S. Conf. Society of Fermentation Technology 379-381. pp. Japan: ContentsofLilly's folder: offprint, drafts. (64) 1972 The use of immobilised enzymes in the food industry. Proc. Int. Symp. Conversion and Manufacture of Foodstuffs by Microorganisms. pp. 65-74. Tokyo: Saikon Pub. Co. Ltd Offprint only. (65) 1973 (With D. Warburton and P. Dunnill) Conversion of benzylpenicillin to 6-aminopenicillanic acid in a batch reactor and continuous feed-stirred tank reactor using immobilised penicillin amidase. Biotechnol. Bioeng. |5, 13- 25 ContentsofLilly’s folder: offprint, correspondence, draft. (66) 1973 (With G. Street, P. Dunnill and V.A.S. Glover) Large scale isolation of choline acetyltransferase from ox brains. Biotechnol. Bioeng. 15, 271-283 ContentsofLilly's folder: offprint, correspondence,draft. (67) 1973 (With P.P. Gray and P. Dunnill) The clarification of mechanically disrupted yeast suspensions by rotary vacuum precoatfiltration. Biotechnol. Bioeng. 15, 309-320 ContentsofLilly’s folder: offprint, correspondence,draft. 86 1972 1972 1972 1973 1973 1973 D.110 (68) 1973 (With P.J. Robinson and P. Dunnill) The properties of magnetic supports in relation to immobilised 1973 M.D.Lilly NCUACS150/7/06 D.111 D.112 D.113-D.114 D.115-D.116 Publications, D.1-D.366 enzymereactors. Biotechnol. Bioeng. 15, 603-606 ContentsofLilly’s folder: offprint, correspondence,drafts. (69) 1973 (With P.P. Gray and P. Dunnill) The effect of controlled feeding of glycerol on R-galactoside production by Escherichia coli in batch culture. Biotechnol. Bioeng. 15, 1179-1188 ContentsofLilly’s folder: offprint, correspondence,drafts. (70) 1973 (With Dunnill) The bioengineering of immobilised enzymes. Biochimie 55, 985- 990 O'Neill and P. S.P. Contents ofLilly’s folder: offprint, correspondence,drafts. (71) 1973 (With precipitation of Saccharomyces Biochim. Biophys. Acta 317, 505-516 P.R. enzymes cerevisiae from by Foster and Dunnill) The P. cell extracts of polyethyleneglycol. 87 1973 1973 1973 Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, drafts. (72) 1974 (With B.C. Buckland, W. Richmond and P. Dunnill) The large-scale isolation of intracellular microbial enzymes: cholesterol oxidase from Nocardia. |In Industrial Aspects of Biochemistry (ed. B. Spencer). pp. 65-79. Amsterdam: FEBS Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, drafts. 1973-1974 D.117 (73) 1974 (With D.L. Regan and P. Dunnill) Immobilized enzyme reactor stability: attrition of the support material. Biotechnol. Bioeng. 16, 333-343 ContentsofLilly's folder: offprint, correspondence,draft. D.118-D.119 (74) 1974 (With P. Dunnill) Teaching and research in biochemical engineering. The Chemical Engineer 286, 396-398 1974 1974 M.D.Lilly NCUACS150/7/06 88 Publications, D.1-D.366 Contents of Lilly's folder divided into two for ease of reference:offprint, correspondence,drafts. D.120 (75) 1974 (With P. Dunnill) Recent developments in enzyme isolation processes. In Enzyme Engineering vol. 2, (ed. E.K. Pye and L.B. Wingard Jr.), pp. 43-45. New York: Plenum Press 1973-1974 Contents ofLilly’s folder: offprint, correspondence,drafts. D.121-D.122 (76) 1974 (With D.L. Regan and P. Dunhill) Well-mixed immobilized enzyme reactors. In Enzyme Engineering, vol. 2, (ed. E.K. Pye and L.B. Wingard Jr.), pp. 245-251. New York: Plenum Press Contents of Lilly’s folder divided into two for ease of reference: off-print, correspondence,drafts. 1973-1974 D.123-D.124 (77) 1974 Biochemische reaktoren. Chemie. Ingenieur Technik 46, 684-689 1973-1974 Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, English and German versions etc. D.125-D.126 (78) 1974 (With P. Dunnill) Purification of enzymes using magnetic bio-affinity. Biotechnol. Bioeng. 16, 981- 990 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence,drafts. D.127-D.129 (79) 1974 (With D.L. Regan and P. Dunnill) Influence of intraparticle diffusional limitation on the observedkinetics of design. and Biotechnol. Bioeng. 16, 1081-1093 immobilized enzymes on catalyst 1974 1974 Contents of Lilly’s folder divided into three for ease of reference: offprint, correspondence, drafts, manuscript working. D.130-D.132 (80) 1974 (With P.J. Robinson, M.A. Wheatley, J.-C. Lanson and P. Dunnill) Pilot scale affinity chromatography: 1974 M.D.Lilly NCUACS150/7/06 D.133-D.135 D.136-D.138 D.139-D.141 D.142-D.146 Publications, D.1-D.366 purification of B-galactosidase. Biotechnol. Bioeng. 16, 1103-1112 Contents of Lilly’s folder divided into three for ease of reference: offprint, correspondence,drafts. (81) 1975 (With J.R. Wykes and P. Dunnill) Cofactor recycling in an enzyme reactor. A comparison using free and and immobilized NAD. Biotechnol. Bioeng. 17, 51-68 dehydrogenases immobilized with free Contents of Lilly's folder divided into three for ease of reference:offprint, correspondence,drafts. (82) 1975 (With B.C. Buckland and P. Dunnill) The enzymatic transformation of water-insoluble reactants in non-aqueous solvents. to cholest-4-ene-3-one by a Nocardia sp. Biotechnol. Bioeng. 17, 815-826 Conversion cholesterol of Contents of Lilly’s folder divided into three for ease of reference: offprint, correspondence, drafts. (83) 1975 (With P. Dunnill) Protein extraction and recovery from microbial cells. In Single Cell Protein || (eds. S.R. Tannenbaum and D.I.C. Wang), 179-207. Cambridge Mass.: MIT Press Contents of Lilly’s folder divided into three for ease of reference: photocopy of published text, letter to publisher, drafts. 1975 (With P. K. (84) Affinity chromatography of enzyme cofactors: the separation of NAD on immobilised dehydrogenase columns. Biochim. Biophys. Acta, 397, 277-287 Das and Dunnill) 89 1974-1975 1975 1975 1974-1975 Contents of Lilly's folder divided into five for ease of reference: offprint, correspondence,drafts. D.147-D.149 (85) 1975 (With C.J.L. MacLeod and P. Dunnill) The synthesis of B-galactosidase by constitutive and other regulatory mutants of Escherichia coli in chemostat culture. J. Gen. Microbiol. 89, 221-228 1975 M.D.Lilly NCUACS150/7/06 D.150 D.151 D.152-D.159 Publications, D.1-D.366 Contents of Lilly's folder divided into three for ease of reference: offprint, correspondence, drafts. (86) 1975 (With P.A. Munro and P. Dunnill) Magnetic particles as supports in immobilised enzyme reactor. /EEE Trans. on Magnetics, MAG-11 (5), 1573-1575. Contents of Lilly’s folder: photoocpy of published text. (87) 1975 (With teaching: Process Biochem. 10, 17-20 a foundation P. for Dunnill) Biochemical engineering industries. biological the Offprint only. (88) 1976 (With P.R. Foster and P. Dunnill) The kinetics of protein of yeast enzymes by ammonium sulfate. Biotechnol. Bioeng. 18, 545-580 precipitation salting-out: 90 1975 1975 1975-1976 Contents of Lilly’s folder divided into eight for ease of reference: offprint, correspondence, drafts. D.160-D.161 Dunnill) The (89) 1976 (With B.C. Buckland and P. kinetics of cholesterol oxidase synthesis by Nocardia rhodochrous. Biotechnol. Bioeng. 18, 601-621 1975-1976 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. D.162 D.163 (90) 1976 (With Z. Duvnjak) The immobilization of glucose oxidase to manganese oxide. Biotechnol. Bioeng. 18, 7- 739 1975-1976 ContentsofLilly’s folder: offprint, correspondence,draft. 1976 (With (91) S. W. Smith and P.Dunnill) The deacylation of benzylpenicillin by immobilized enzyme.In Proc. Vth Int. Fermentation Symp. (ed. H. Dellweg), p. 301. Berlin: Verlag Versuchs und Lehranstalt 1976 Offprint only. M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.164 D.165 (92) 1976 (With P.S.J. Cheetham, D.J. Lewis, J. Yates and P. Dunnill) Conversion of cholesterol to cholestenone, androstenedione and androstadienedione.In Proc. Vth Int. Fermentation Symp. (ed. H. Dellweg), p. 327. Berlin: Verlag Versuchs und Lehranstalt Offprint only. 1976 (With P. and (93) postgraduate teaching of biochemical engineering. In Proc. Vth Int. Fermentation Symp. (ed. H. Dellweg), p. 461. Berlin: Verlag Versuchs und Lehranstalt Undergraduate Dunnill) Offprint only. D.166-D.167 (94) 1976 Enzymes immobilized to cellulose. In Methods in Enzymology XLIV: Immobilized Enzymes (ed. K. Mosbach), pp. 46-53. New York: Academic Press Contents of Lilly's folder divided into two for ease of reference: version, correspondence, drafts. photocopy published of 91 1976 1976 1976 D.168-D.172 (95) 1976 (With P. Dunnill) Immobilized-enzyme reactors. In Methods in Enzymology XLIV: Immobilized Enzymes (ed. K. Mosbach) pp.717-738. New York: Academic Press 1974-1976 Contents of Lilly’s folder divided into five for ease of reference: version, correspondence, drafts. photocopy published of D.173 D.174 (96) 1977 (With P.A. Munro and P. Dunnill) Nonporous magnetic materials as enzyme supports: studies with immobilized chymotrypsin. Biotechnol. Bioeng. 19, 101- 124 ContentsofLilly’s folder: offprint, correspondence,draft. 1976-1977 (97) 1977 A comparison of cells and enzymesasindustrial catalysts. In Biotechnological Applications of Proteins and Enzymes.pp.127-39. (ed. A. Bohak and N. Sharon). New York: Academic Press 1976-1977, 1987 ContentsofLilly’s folder: offprint, correspondence, draft. M.D.Lilly NCUACS150/7/06 92 Publications, D.1-D.366 D.175-D.176 (98) 1978 (With P.S.J. Cheetham and P. Dunnill) Mass transfer problems with immobilized oxidases. In Enzyme Engineering 3 (ed. E.K. Pye and H.H. Weetall). pp. 72-78. New York: Plenum Press 1975, 1978 Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, drafts including draft for talk in Portland, Oregon in 1975. D.177-D.178 D.179 (99) 1978 (With J.J. Higgins. D.J. Lewis. W.H. Daly. F.G. Mosqueira and P. unit operations involved in the continuous flow isolation of B- galactosidase from Escherichia coli. Biotechnol. Bioeng. 20, 159-182 Investigation Dunnill) of the Contents of Lilly’s folder divided into two for ease of reference:offprint, correspondence,drafts. 1st. (100) 1979 Immobilized enzyme reactors. European |In Dechema Monograph 82. pp.165-180. Frankfurt am Main: Verlag Chemie Biotechnology Congress on Proc. 1977-1978 1979 Offprint only. D.180-D.184 (101)1979 (With D.I.C. Wang, C.L. Cooney, A.L. Demain. P. Dunnill and A.E. Humphrey) Fermentation and enzyme technology. New York: Wiley. 1975-1981 Contents ofLilly’s folder so inscribed divided into five for ease of drafts, reviews, etc correspondence, reference: offprint, D.185 (102) 1979 (With S W Carleysmith) Deacylation of benzylpenicillin by immobilized penicillin acylase in a continuous four-stage Biotechnol. Bioeng. 21, 1057-1073 stirred-tank reactor. Offprint only. D.186-D.187 (103) 1979 Production of intracellular microbial enzymes. In Appl. Biochem. Bioeng. Vol 2. (ed. L.B. Wingard Jr.. E. Katchalski-Katzir and L. Goldstein). pp.1-26. New York: Academic Press. 1979 1979 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.188 D.189 D.190 D.191 D.192 D.193 Contents of Lilly’s folder divided into two for ease of reference (104) 1979 (With A.W. Nienow) Power drawn by multiple impellers in sparged agitated vessels. Biotechnol. Bioeng. 21, 2341-2345 Offprint only. 1980 (With W.H. Dunnill) (105) Optimization of the production of progesterone Il a- hydroxylase by Rhizopus nigricans. Biotechnol. Bioeng. 22, 555-570 Hanisch and P. Offprint only. (106) 1980 (With S. W. Carleysmith and P. Dunnill) Kinetic behaviour of immobilized penicillin acylase. Biotechnol. Bioeng. 22, 735-756. Offprint only. (107) 1980 (With S.W. Carleysmith and M.B.L. Eames) Staining method for determination of the penetration of immobilized enzyme into a porous support. Biotechnol. Bioeng. 22, 957-967 Offprint only (108) 1980 (With Extraction rhodochrous. Enzyme Microb. Technol. 2, 201-205 P.S.J. Cheetham and P. cholesterol oxidase from of Dunnill) Nocardia Offprint only. (109) 1980 (With S. W. Carleysmith and P. Dunnill) Deacylation of benzylpenicillin by immobilized penicillin acylase. Biochimie 62, 317-321 Offprint only. 93 1979 1980 1980 1980 1980 1980 M.D.Lilly NCUACS 150/7/06 Publications, D.1-D.366 D.194 D.195 D.196 D.197 D.198 D.199 (110) 1980 (With J.M.C. Duarte) The use of free and immobilized cells in the presence of organic solvents: the oxidation In Enzyme Engineering 5 (ed. H.H. Weetall and G.P. Royer). pp. 363-367. New York: Plenum Press of cholesterol by Nocardia rhodocrous. Offprint only. (111) 1981 (With J.A. Asenjo and P. Dunnill) Production of yeast-lytic enzymes by Cytophaga species in batch culture. Biotechnol. Bioeng. 23, 97-109 Offprint only. (112) 1981 (With F.G. Mosqueira. J.J. Higgins and P. Dunnill) Characteristics of mechanically disrupted bakers’ yeastin relation to its separation in industrial centrifuges. Biotechnol. Bioeng. 23, 335-343 Offprint only. (113) 1981 (With I.S. Maddox and P. Dunnill) Use of immobilized a- hydroxylation of progesterone. Biotechnol. Bioeng. 23. 345-354 of Rhizopus nigricans cells for the Offprint only. Dunnill) Casein (114) 1981 (With P.A. Munro and P. hydrolysis in stirred tank reactors using chymotrypsin immobilized on magnetic supports. Biotechnol. Bioeng. 23, 677-689 Offprint only. (115) 1982 (With P.S.J. Cheetham and P. Dunnill) The characterization and interconversion of three forms of cholesterol oxidase extracted from Nocardia rhodochrous. Biochem J. 201, 515-521 Offprint only. 94 1980 1981 1981 1981 1981 1982 M.D.Lilly NCUACS150/7/06 D.200 D.201 D.202 D.203 D.204 D.205 Publications, D.1-D.366 (116) 1982 (With F. Vardar) The measurement of oxygen- transfer coefficients in fermentors by frequency response techniques. Biotechnol. Bioeng. 24, 1711-1719 ContentsofLilly's folder: offprint, draft. (117) 1982 (With F. Vardar) Effect of cycling dissolved oxygen concentrations on product formation in penicillin fermentations. European J. Appl. Microbiol. Biotechnol. 14, 203-211 Offprint only. (118) 1982 (With N.M. Fish and D.J. Allenby) Oxidation of n-alkanes: growth of Pseudomonas putida. European J. Appl. Microbiol. Biotechnol. 14, 259-262 (119) 1982 Two-liquid-phase biocatalytic reactions. Chem. Tech. Biotechnol. 32,162-169 J. Offprint only. (120) 1982 (With B. McDougall and P. Dunnill) Enzymic acylation of 6-aminopenicillanic acid. Enzyme Microb. Technol. 4, 114-115 Offprint only. (121) 1982 (With A.T. Bull and G. Holt) Biotechnology - International Trends and Perspectives. OECD, Paris. (also published in French. German. Greek. Japanese. Spanish and Turkish) Duplicated typescript only. 95 1981 1982 1982 1982 1982 1982 D.206 (122) 1983 Two-liquid phase biocatalytic reactors. Phil. Trans. R. Soc. Lond. 300, 391-398 1983 Offprint only. M.D.Lilly NCUACS150/7/06 D.207 D.208 D.209 D.210 D.211-D.212 Publications, D.1-D.366 (123) 1983 Problems in process scale-up. In Bioactive Microbial Products 2. D.J. Winstanley and L.J. Nisbet). pp. 79-89. London: Academic Press (ed. Offprint only. (124) 1983 (With N.M. Fish. S. Harbron and D.J. Allenby) Oxidation of n-alkanes: isolation of alkane hydroxylase from Pseudomonasputida. European J. Appl. Microbiol. Biotechnol. 17, 57-63 Offprint only. 1984 (With (125) between fermentation and protein recovery. Biotechnology 2, 623- 628 Interactions Fish) N.M. Contents ofLilly’s folder: offprint, draft. 1984 J. (With (126) of supersaturated aqueous hydrocortisone concentrations on A'-dehydrogenase activity. Enzyme Microb. Technol. 4, 113-116 Kloosterman Effect IV) ContentsofLilly’s folder: offprint, draft, covering letter. (127) 1984 (With R.A. Wisdom. P. Dunnill and A. Macrae) Enzymic interesterification influencing choice of support for immobilized lipase. Enzyme Microb. Technol. 6, 443-446 of fats: factors 96 1983 1983 1984 1983-1984 1983-1984 Contents of Lilly's folder divided into two for ease of referemce: offprint, correspondence, drafts. D.213 (128) 1985 (With J. Kloosterman IV) Anairlift loop reactor for the transformation of steroids by immobilized cells. Biotechnol. Lett. 7, 25-30 1985 ContentsofLilly's folder: offprint, correspondence, draft. D.214-D.219 (129) 1985 (With T. Keshavarz and P.H. Clarke) Stability of a catabolic plasmid in continuous culture. J. Gen. Microbiol. 131, 1193-1203 1984-1985 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 Contents of Lilly's folder divided into six for ease of reference: offprint, correspondence,drafts. D.220 D.221-D.222 D.223-D.225 D.226 D.227 (130) 1985 (With J.M.C. Duarte) Cholesterol degradation by in solvents. Annals N. Y. Acad. Sci. 434, 573-576 polymer-entrapped Nocardia organic ContentsofLilly’s folder: offprint, draft. (131) 1985 (With J. Kloosterman 1 V) Maintenance and operational stability of immobilized Arthrobacter simplex for the A' dehydrogenation of steroids. Enzyme Microb. Technol. 7, 377-382 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. (132) 1985 (With R.A. Wisdom and P. Dunnill) Enzymic interesterification of fats: the effect of non-lipase material on immobilized enzyme activity. Enzyme Microb. Technol. 7, 567-572 Contents of Lilly’s folder divided into three for ease of reference: offprint, correspondence,drafts. (133) 1985 (With S. Harbron and T.J. Narendranathan) Effects of mass transfer on the kinetic behaviour of two- liquid phase biocatalytic reactions. Proc. 3rd. European Congress Biotechnol. vol. IV pp. 369-374. Weinheim: VCh. Contentsof Lilly’s folder: offprint, draft. water-insoluble (134) 1985 (With J .M. Woodley) Biocatalytic reactions involving In Biocatalysts in Organic Syntheses (ed. J. Tramper, H.C. van der Plas and P. Linko), pp. 179-192. Amsterdam: Elsevier compounds. organic ContentsofLilly’s folder: offprint, correspondence,draft. 97 1985 1985 1985 1985 1985-1986 M.D.Lilly NCUACS150/7/06 D.228-D.232 D.233 D.234 D.235-D.236 D.237 D.238 D.239 Publications, D.1-D.366 I.K. 1986 (With Drozd) (135) Stereospecific hydrolysis of d,l-menthyl acetate by Bacillus subtilis: mass transfer reaction interactions in a liquid- liquid system. Enzyme Microb. Technol. 8, 53-57 Brookes J.W. and Contents of Lilly’s folder divided into five for ease of reference: offprint, correspondence, drafts. (136) 1986 (With S. Harbron and B. W. Smith) Two-liquid phase by Pseudomonasputida. Enzyme Microb. Technol. 8, 85-88 1,7-octadiene biocatalysis: epoxidation of ContentsofLilly's folder: offprint, correspondence, draft. 1986 Recommendations for (137) to describe the metabolic behaviour of immobilised cells. Enzyme Microb. Technol. 8, 315 nomenclature ContentsofLilly’s folder: offprint, correspondence, draft. (138) 1986 (With J. Kloosterman IV) Pilot plant production of immobilized Arthrobacter simplex. Biotechnol. Bioeng. 28,1390-1395 prednisolone alginate calcium using Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. (139) 1986 Concluding Remarks In Bioactive Metabolic Products 3 Bailey and D.J. Winstanley), pp. 231-233. London: Academic Press Stowell, J.D. (ed. P.J. ContentsofLilly’s folder: offprint, correspondence,draft. (140) 1986 Developments in industrial biocatalysis. Proc. G. 7th. Tregear), Australian Melbourne: Biotechnology Conference Committee Biotechnology 83-88. Australian pp. Conference. (ed. 7th 98 1986 1985-1986 1986 1985-1986 1986 1986 Offprint only (141) 1987 (With S. Harbron and T.J. Narendranathan) Two-liquid phase biocatalytic reactors. In Methods in Enzymology 136C: Immobilized Enzymes and Cells. (ed. 1984-1987 M.D.Lilly NCUACS150/7/06 D.240-D.241 D.242 D.243 Publications, D.1-D.366 K. Mosbach), pp. 138-149. New York: Academic Press Contents ofLilly’s folder: offprint, correspondence,drafts. (142) 1987 (With I.K. Brookes and J.W. Drozd) Use of stereospecific immobilized hydrolysis Enzyme Microb. Technol. 9, 217-220 d,l-menthyl acetate. Bacillus subtilis the for of Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. (143) 1987 (With R.A. Wisdom and P. Dunnill) Enzymic interesterification of fats: laboratory and pilot-scale studies with arrhizus. from Biotechnol. Bioeng. 29, 1081-1085 immobilized Rhizopus lipase ContentsofLilly's folder: offprint, correspondence, draft. P. 1987 (With Dunnill) Use of (144) immobilized biocatalysts for conversions of water-insoluble reactants: interesterification of fats In Enzyme Engineering VIII (ed. A.L. Laskin, K. Mosbach, D. Thomas and L.B. Wingard), Annals N.Y. Acad. Sci. 501, 113-118 Contents of Lilly’s folder: offprint, correspondence,draft. D.244-D.245 (145) 1987 (With A. Freeman) The effect of water-miscible solvents on A'-dehydrogenaseactivity of free and PAAH- entrapped A. simplex. Appl. Microbiol. Biotechnol. 25, 495-501 Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, drafts. D.246 D.247 (146) 1987 Culture systems and bioreactors. In Modelling and Control of Fermentation Processes (ed. J.R. Leigh), pp. 87-96. London: Peter Peregrinus Photocopyof published text only. (147) 1987 (With A.J. Williams and J.M. A.C. conversions Brazier, M.D. Hocknull, Woodley) Biological 99 1985-1987 1986-1987 1987 1986-1987 1987 1987 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 water-insoluble involving In Biocatalysis in Organic Media (ed. C. Laane, J. Tramper and M.D. Lilly), pp. 3-17. Amsterdam: Elsevier compounds. organic Offprint only. (148) 1987 (With M.D. Hocknull) The A'-dehydrogenation of hydrocortisone by Arthrobacter simplex in organic- aqueoustwo-liquid phase environments. In Biocatalysis in Organic Media (ed. C. Laane and J. Tramper), pp. 393- 398. Amsterdam: Elsevier (149) 1987 (With A.C. Williams, J.M. Woodley and P. Ellis) Denaturation and inhibition studies in a two-liquid phase biocatalytic reaction: the hydrolysis of menthyl acetate by pig liver esterase. In Biocatalysis in Organic Media (ed. C. Laane and J. Tramper), pp. 399-404. Amsterdam: Elsevier Offprint only. C. Rice) (150) 1987 (With D.C. Smith, A.T. Bull, G. Holt, C. Christy with and specific reference to chloroperoxidase. ASEAN J. Sci. Technol. Develop.4 (2), 29-43 halogenation Microbial Offprint only. Dunnill) Effect of (151) 1988 (With A.P. Ison and P. solvent catalysed interesterification of fats. Enzyme Microb. Technol. 10, 47- 51 concentration enzyme on ContentsofLilly’s folder: offprint, correspondence, draft. (152) 1988 Biochemical Engineering - Its contribution to society: Hartley Lecture. Science and Public Affairs 3, 121-134 Offprints from Science and Public Affairs and alternative publication in Measurement + Control, May 1988. D.248 D.249 D.250 D.251 D.252 100 1987 1987 1987 1988 1988 D.253 (153) 1988 (With M.D. Hocknull) Stability of the steroid A'- dehydrogenation system of Arthrobacter simplex in- 1988 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 organic solvent-water two-liquid phase environments. Enzyme Microb. Technol. 10, 669-674 Contents of Lilly’s folder: offprint, correspondence,draft. 101 1988 1989 1989 D.254 D.255 D.256 D.257 D.258 (154) 1988 The training of biochemical engineers. In Proceedings Biotechnology Symposium (ed. G. Durand, L. Bobichon and J. Florent), vol. 2, p. 1254. Paris: Societie Francaise de Microbiologie International 8th of Offprint only. (155) 1989 Biochemical engineering for flavour and food production. In Biotechnology Challenges for the Flavour and International Conference Symposium in Williamsburg USA. (ed. R.C. Lindsay and B.J. Willis), pp. 55-63. London: Elsevier Proceedings Industry. Food of Contents of Llly’s folder: photocopy of published version anddraft. (156) 1989 (With A.N.C. Weir, C. Bucke, G. Holt and A.T. Bull) A high-performance liquid chromatography method for simultaneous assay of diaminopimelate epimerase and decarboxylase. Analytical Biochemistry 180, 298-302 Offprint only. (157) 1989 (With G.A. Dervakos, J.M. Woodley, E.T. Keravnou and J. Washbrook) Development of a KBS for biotransformation process design. /. Chem. E. Symposium Series No 114, 283-291 1988-1989 ContentsofLilly's folder correspondence, drafts. (158) 1989 (With T. Keshavarz, E. Walker, R. Eglin, G. Lilley, G. Holt and A.T. Bull) Immobilization of Penicillium chrysogenum: spore growth on Celite. Appi. Microbiol. Biotechnol. 30, 487-491 1989 ContentsofLilly’s folder: M.D. Lilly NCUACS150/7/06 Publications, D.1-D.366 102 1989 Hocknull) difference bacteria. D.259 D.260 D.261 D.262 1989 (With AJ. Harrop and M.D. a_ (159) Biotransformations between Biotechnol. Letters 11, 807-810 Gram-positive and Gram-negative solvents: organic in Contents ofLilly’s folder: offprint, correspondence,draft. Dunnill) Enzymic (160) 1990 (With A.P. Ison and P. interesterification of fats: immobilization and immunogold localization of lipase on ion exchangeresins. Biocatalysis, 3, 329-342 1989-1990 ContentsofLilly’s folder: off-print, correspondence, draft. (161) 1990 (With A.J. Brazier and A.B. Herbert) Toluene cis-glycol synthesis by Pseudomonasputida; kinetic data for reactor evaluation. Enzyme Microb. Technol. 12, 90-94 1988-1990 ContentsofLilly's folder: offprint, correspondence,draft. (162) 1990 (With A.C. Williams, J.M. Woodley, P.A. Ellis liver and T.J. Narendranathan) A comparison of pig esterase and Bacillus for the hydrolysis of menthyl acetate in stirred two-liquid phase reactors. Enzyme Microb. Technol. 12, 260-265 subtilis as catalysts 1988-1990 Contents ofLilly’s folder: offprint, D.263-D.264 (163) 1990 (With J.J. Smith and R. Fox) The effect of agitation on the morphology and penicillin production of Penicillium chrysogenum. Biotechnol. Bioeng. 35, 1011- 1023 1988-1990 Contents of Lilly’s folder divided into two for ease of reference: manuscript working. correspondence, offprint, draft, D.265 Pilot-scale (164) 1990 (With T. Keshavarz, C. Bucke, A.T. Bull and G. Holt) Penicillium chrysogenum. In Physiology of Immobilized Cells (ed. J.A.M. de Bont, J. Visser, B. Mattiasson and J. Tramper), pp. 369-375. Amsterdam: Elsevier immobilised studies of 1990 Offprint only. M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.266 D.267 D.268 D.269-D.270 D.271 D.272-D.273 (165) 1990 (With M. Hocknull) The use of free and organic immobilised solvent/aqueous Appl. Microbiol. Biotechnol. 33, 148-153 Arthrobacter two-liquid simplex phase reactors. in Contents of Lilly’s folder: offprint, correspondence, draft, figures. (166) 1990 (With J.M. Woodley) Extractive biocatalysis: the use of two-liquid phase biocatalytic reactors to assist product recovery. Chem. Eng. Sci. 45, 2391-2396 Offprint only. (167) 1990 (With G.A. Dervakos and J.M. Woodley) Two- liquid phase biocatalysis: In Opportunities in Biotransformations (ed. L.G. Copping, R.E. Martin, J.A. Pickett, C. Bucke and A. W. Bunch), pp. 5-16. London: Elsevier choice of phase ratio. Photocopyof published text only. G. Holt and A.T. (168) 1990 (With T. Keshavarz, R. Eglin, E. Walker, C. Bucke, large-scale immobilization of Penicillium chrysogenum. batch and continuous operation Biotechnol. Bioeng. 36, 763-770 reactor. airlift Bull) in an_ The Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, drafts. (169) 1990 (With A.R. Russell and C.R. Thomas) The hydrodynamics ofa pilot-scale airlift fermenter. Proc. 5th European C. Christiansen, L. Munct and J. Villadsen), pp. 809-812. Copenhagen: Munksgaard. Biotechnolog. Congress (ed. on_ Photocopyof published text only. (170) 1991 (With J.M. Woodley and A.J. Brazier) Lewis cell studies to determine reactor design data for two-liquid phase Biotechnol. Bioeng. 37, 133-140 and enzymic reactions. bacterial 103 1989-1990 1990 1990 1990 1990 1991 M.D.Lilly NCUACS150/7/06 D.274 D.275 D.276 D.277 D.278 Publications, D.1-D.366 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, referee’s comment, draft, figures. (171) (With J.M. Woodley and A.J. Harrop) The impact of biocatalyst selection on the design of aqueous-organic biophase biocatalytic processes. Enzyme Engineering, 10, 191-200 Offprint only. (172) 1991 (With J. M. Woodley and P.J. Cunnah) Stirred tank two-liquid phase biocatalytic reactor studies: kinetics, evaluation and modelling of transfer. Biocatalysis, 5, 1-12 (173) 1991 (With K. Gbewonyo and B.C. Buckland) Development of a large-scale continuous substrate feed process for the by Nocardia sp. Biotech. Bioeng. 37, 1101-1107 biotransformation of Simvastatin Offprint only. (174) 1991 (With M.W. Adlard, B.M. Gordon, C. Bucke, A.T. Bull and G. Holt) A HPLC procedure for monitoring penicillin G fermentations. Biotechnol. Techniques 5, 121- 126 Offprint only. (175) 1992 (With H.P. Packer and E. Keshavarz-Moore) The estimation of cell volume and biomass of Penicillium chrysogenum using image analysis. Biotechnol. Bioeng. 39, 384-391 ContentsofLilly’s folder: offprint, correspondence. 104 1971 1991 1991 1991 1992 D.279-D.280 (176) 1992 (With F. Villesid) Influence of dissolved oxygen tension on the synthesis of catechol, 1,2-dioxygenase by Pseudomonas putida. Enzyme Microb. Technol. 14, 561- 565 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, referees’ comments, 1991-1992 M.D.Lilly NCUACS150/7/06 D.281-D.282 D.283 D.284 D.285 D.286-D.287 Publications, D.1-D.366 drafts. A.J. 1992 (With (177) Harrop and J.M. Woodley) Production of naphthalene-cis-glycol by Pseudomonas putida in the presence of organic solvents. Enzyme Microb. Technol. 14, 725-730 Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, referees’ comments, draft. 1992 Biochemical (178) its contribution to the biological industries. Trans. |. Chem. E. 72C, 3-6 engineering research: Contents of Lilly’s folder: offprint, draft. (179) 1992 Design and operation of biotransformation processes. Recent Advances in Biotechnology In NATO ASI Series E. Vol. 210. (ed. F. Vardar Sukan and S. Suha Sukan), pp. 47-68 Offprintonly. (180) 1992 (With J.M. Woodley) Process engineering of two-liquid phase biocatalysis. In Biocatalysis in Non- Conventional Media (ed. J. Tramper, M.H. Vermue, A.H. Beeftink and U. von Stocker) pp. 147-154. Amsterdam: Elsevier Offprint only. (182) 1992 (With A.P. Ison and P. Ayazi Shamlou) The influence of the physical environment in fermenters on antibiotic production by microorganisms. In Harnessing Biotechnology for the 21st Century (ed. M.R. Ladisch and A. Bosse), pp. 219-222. Washington: American Chemical Society Contents of Lilly’s folder divided into two for ease of reference: typescript of paper and correspondence and papers re 9th International Biotechnology Symposium at which the paper wasdelivered. 105 1991-1992 1992 1992 1992 1992 M.D.Lilly NCUACS150/7/06 D.288-D.291 D.292-D.294 D.295 D.296 D.297 Publications, D.1-D.366 (184) 1993 (With overview. Stephanopoulos). pp.7-22. Weinheim: VCH B. C Buckland) Fermentation: an G. Biotechnology Vol. (ed. In 3 Contents of Lilly’s folder divided into four for ease of reference: photocopy of published text, correspondence, manuscript notes, background papers. (185) 1993 (With H.Y. Makiagansar, P. Ayazi Shamlou and C.R. Thomas). The influence of mechanical forces on the morphology and penicillin production of Penicillium chrysogenum. Bioprocess Engineering 9, 83-90 Contents of Lilly's folder divided into three for ease of reference: offprint, correspondence, drafts. (186) 1993 (With G.R. Hobbs, N.J. Turner, J.M. Ward, A.J. Willets and J.M. Woodley) Enzyme catalysed carbon- carbon from Escherichia coli. J. Chem. Soc. Perkin Transactions |, 165-166 transketolase formation: bond use of 106 1982-1993 1993 1993 Offprint only. (187) 1993 (With A. Freeman and J.M. Woodley) In situ product removal as a tool for bioprocessing - an overview. Biotechnology II, 1007-1012 1992-1993 ContentsofLilly’s folder: offprint, correspondence,draft. (188) 1993 (With R. Lynch and J.M. Woodley) The characterization to fluorocatechol by Pseudomonas putida leading to large scale bioreactor design. In Proc. 1993 |. Chem. E. Research Event, pp.51-54. Rugby: I|.Chem. E. fluorobenzene oxidation of 1993 Offprint only. D.298-D.300 (189) 1994 Advances in biotransformation processes. Chem. Eng. Sci. 49 C, 151-159. (Danckwerts Lecture) 1993-1994 Contents of Lilly’s folder divided into three for ease of reference:offprints, correspondence,draft. M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.301 D.302 D.303 D.304 D.305 D.306 (190) 1994 (With N. Rosen, J.M. Woodley and A.T. Bull) Enzymatic dehalogenation of halo-alkanes and _halo- alcohols. Proc. 1994 |. Chem. E. Research Event, pp. 91- 93. Rugby: |. Chem. E. Offprint only. (191) 1994 (With G.R. Hobbs, C. French, M. Gyamerah, G. Morris, N.J. Turner, J.M. Ward, A.J. Willetts and J.M. Woodley). Development of a process for transketolase catalysed carbon-carbon bond formation. Proc. 1994 |. Chem. E. Research Event, pp.247-249. Rugby: I. Chem. E. Offprint only. (192) 1994 (With G.R. Hobbs., N.J. Turner, J.M. Ward and J.M. Woodley) Transketolase production for use as a catalyst for carbon-carbon bond formation. Proc. 1994 I. Chem. E..Research Event, pp. 289-291. Rugby: |. Chem. E. Offprint only. (193) 1994 (With A.B. Russell and C.R. Thomas) The influence of vessel height and top-section size on the hydrodynamic characteristics ofairlift fermenters. Biotech. Bioeng. 43, 69-76 Contents ofLilly's folder: offprint, figures, correspondence, referees’ comments (194) 1994 (With C.J. Hack, J.M. Woodley and J.M. Liddell) The production of Pseudomonas putida for the hydroxylation of toluene to its cis-glycol. Appl. Microbiol. Biotechnol. 41, 495-499 Contents ofLilly’s folder: offprint, draft. (195) 1994 (With P. Ayazil Shamlou, D.J. Pollard and A.P. Ison) Gas holdup andliquid circulation rate in concentric- tube airlift bioreactors. Chem. Eng. Sci. 49, 303-312 Contentsof Lilly’s folder: offprint, correspondence, draft. 107 1994 1994 1994 1994 1994 1994 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.307 D.308 (196) 1994 (With P. Ayazi Shamlou, H. Makiagamsar, A.P. Ison and C.R. Thomas) Turbulent breakageoffilamentous microorganisms in submerged culture in mechanically stirred bioreactors. Chem. Eng. Sci. 49, 2621-2631 Offprint only. M.E. Cavanagh, A.P. (197) 1994 (With Ison, S.W. Carleysmith and J. Edwards) The utilisation of lipids during Streptomycete fermentations. Trans. |. Chem. E. 72 C, 14-16 Offprint only. 108 1994 1994 D.309-D.311 (198) 1994 (With J.M. Woodley) Biotransformation reactor selection and operation. In Applied Biocatalysis (ed. J.M.S. Cabral, D. Best, L. Boross and J. Tramper), pp. 371-394. Chur: Harwood Academic 1992-1994 D.312 D.313 D.314 Contents of Lilly’s folder divided into three for ease of reference: copy of published text, correspondence, draft. (199) 1994 (With G.R. Hobbs, N.J. Turner, J.M. Ward and J.M. Woodley) Developmentof transketolase as a catalyst for carbon-carbon bond formation. Prog. Biotechnol. 9, 463-466 Offprint only. (200) 1994 With M. Suphantharika, A.P. Ison and B.C. Buckland) The influence of dissolved oxygen tension on the synthesis of the antibiotic difficidin by Bacillus subtilis. Biotechnol. Bioeng. 44, 1007-1012 Contents of Lilly's folder: photocopy of published text, drafts, referee’s comments and response. (201) 1994 (With H.L. Packer and C.R. Thomas) The effect Penicillium chrysogenum.Biotechnol. Techniques, 8, 601-604 blending speed of high upon Offprint only. 1994 1994 1994 M.D.Lilly NCUACS150/7/06 109 Publications, D.1-D.366 D.315 (203) 1995 (With S.J. Warren, E. Keshavarz-Moore, C.R. Thomas and K. Dixon) Rheologies and morphologies of three Actinomycetes in submerged culture. Biotechnol. Bioeng. 45, 80-85. 1994-1995 Contents of Lilly’s folder: draft. offprint, referees’ comments, D.316-D.317 (204) 1995 (With A.B. Russell and C.R. Thomas) Oxygen transfer measurements during yeast fermentation in a pilot-scale airlift fermenter. Bioprocess Engineering 12, 71-79 Contents of Lilly's folder divided into two for ease of reference:offprint, correspondence,drafts. D.318 D.319 D.320 D.321 (205) 1995 (With S.J. Warren, E. Keshavarz-Moore, P. Ayazi Shamlou, C.R. Thomas and K. Dixon) Rheological measurements in Actinomycetes submerged culture. Bioprocess Engineering 13, 45-48 different three of Contents of Lilly’s folder: photocopy of published paper, correspondence. (206) 1995 (With C. T. Marshall, K. Gowewonyo and B.C. Buckland) Use of comparative for evaluation of the effect of sterilization conditions on fermentations to produce acidic fibroblast growth factor. Biotechnol. Bioeng. 47, 688-695 reasoning tools Photocopy of published paper. (207) 1995 (With G.A. Dervakos, J.M. Woodley and J. Washbrook) Use of intelligent knowledge-based system for the design of biotransformation processes. Trans. |. Chem. E. 73 C, 133-139 an_ Contents referees’ reports, draft. Lilly's of folder: offprint, correspondence, (208) 1995 (With M. Suphantharika and A.P. Ison) The effect of cycling dissolved oxygen tension on the synthesis of the antibiotic difficidin by Bacillus subtilis. Bioprocess Engineering 12, 181-186 1995 1995 1995 1995 1995 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 Contents of Lilly’s folder: photocopy of published paper, figures. D.322 D.323 D.324 D.325 Rawas and (209) 1995 (With J.A. Littlechild, N.J. Turner, G.R. Hobbs, A. and preliminary x-ray crystallographic data with Escherichia coli transketolase. Acta Cryst. D, 51, 1074-1076 Crystallisation Watson) H.C. Offprint only. (210) 1996 (With T. Keshavarz and C. Bucke) Problemsin scale-up of immobilised cell cultures. In /mmobilised cells: Basics and Applications (ed. R.H.Wijffels, R.M. Buittelaar and C. Bucke), pp. 505-510. Amsterdam: Elsevier Offprint only. P.S.J. Poulsen, (211) 1996 (With R.H. Wijffels, R.M. Buitelaar, C. Bucke, P.B. Tramper) Guidelines for the characterization of immobilized cells. In Immobilized Cells: Basics and Applications (ed. R.H. Wijffels, R.M. Buitelaar, C. Bucke and J. Tramper), p.831- 834. Amsterdam: Elsevier Cheetham and J. of Contents correspondence including re arrangements for conference on immobilized cells. offprint, folder: Lilly's (212) 1996 (With G.R. Hobbs, R.K. Mitra, R. Chauhan and J.M. Woodley) Enzyme-catalysed carbon-carbon bond formation: coli transketolase. J. Biotechnol. 45, 173-179 of Escherichia large-scale production 110 1995 1996 1996 1996 ContentsofLilly's folder: offprint, drafts. D.326-D.327 (213) 1996 (With R. Chauhan, C. French, M. Gyamerah, G.R. Hobbs, A. Humphrey, J.A. Littlechild, R. Mitra, G. Morris, M. Rupprecht, N.J. Turner, J.M. Ward, A. Willetts and J.M. Woodley) Carbon-carbon bond synthesis: the impact of rDNA technology on the production and use of E. coli trans-ketolase. Annals N. Y. Acad. Sci. 782, 513- 525 Contents of Lilly’s folder: photocopy of published paper, 1994-1996 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 correspondence,referees’ comments,drafts. D.328 D.329-D.330 D.331 D.332 D.333 Mitra and J.M. (214) 1996 (With K.G. Morris. M.E.B. Smith, N.J. Turner, R.K. from Escherichia coli: a practical procedure for using the biocatalyst synthesis. Tetrahedron Asymmetry, 7, 2185-2188 Woodley) Transketolase carbon-carbon for asymmetric Offprint only. 1996 Biotransformations (215) immobilized biocatalysts. In Advances in Molecular and Cell Biology, vol. 15 A (ed. Bengt Danielson), pp. 139-147. London: JAI Press using Contents of Lilly’s folder divided into two for ease of reference: offprint, correspondence, draft. (216) 1996 (With J .M. Woodley) Selection and design of biotransformation processes. Chem. Eng, 611, 28-30 ContentsofLilly's folder: offprint, draft. (217) 1996 (With J.M. Woodley and R.K. Mitra) Carbon- carbon bond synthesis: reactor design and operation for transketolase catalysed transformations. Ann. N. Y. Acad. Sci. 799, 434-445 Offprint only. (218) 1996 (With S.P. Brocklebank, R.K. Mitra and J.M. Woodley) Carbon-carbon bond synthesis: preparation and use of immobilised transketolase. Ann. N. Y. Acad. Sci. 799, 729-736 Contents ofLilly's folder: copy of ? published text, letter re acceptance of paperofthis title for a conference poster presentation. 111 1996 1992-1996 1996 1996 1995-1996 D.334-D.335 (219) 1996 (With J.M. Woodley) A structured approach to design and operation of biotransformation processes. J. Ind. Microbiol. 17, 24-29 1996 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 Contents of Lilly's folder divided into two for ease of reference: draft, photograph, figures, drafts. enclosing offprint, revised letter (220) 1996 (With D.J. Pollard, P. Ayazi Shamlou and A.P. Ison) Saccharomyces cerevisiae fermentation in a pilot airlift bioreactor: comparison of air sparger configurations. Bioprocess Engineering 15, 179-288 Offprint only. (221) 1996 (With S. Dawson) synthesis Biotechnol. Progr. 12, 758-763 Characterisation of Blayer, J.M. Woodley and M.J. chemo-enzymatic acid (NeuSAc). the N-acetyl-A-neuraminic of Offprint only. biomass (222) 1996 (With M. Sarra and A.P. Ison) The relationship between a rheology and morphology of capitance-based Saccharopolyspora erythraea cultures. J. Biotechnol. 51, 157-165 concentration. determined probe, by Contentsof Lilly’s folder: offprint, drafts. of (223) 1996 (With S.M. Heydarian and A.P. Ison) The effect of erythromycin by Saccharopolyspora erythraea in batch culture. Biotechnol. Lett. 18, 1181-1186 conditions on the productivity culture D.336 D.337 D.338 D.339 Contentsof Lilly's folder: figures only. D.340 (224) 1997 The development of biochemical engineering science in Europe. J. Biotechnol. 59, 11-18 Contents of Lilly’s folder inscribed by Sheila Lilly ‘First Lecture given by MDL at Opening of ESBES| introduced by Karel Luyben ‘as the “father” of European Biochemical Engineering’: offprint, draft, figures. 112 1996 1996 1996 1996 1997 D.341 (225) 1997 (With D.J. Pollard, A.P. Ison and P. Ayazi Shamlou) Influence of a propeller on Saccharomyces 1997 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 cerevisiae Bioprocess Engineering 16, 274-279 fermentations in a_ pilot-scale bioreactor. Contents ofLilly’s folder: offprint, figures. D.342-D.343 (226) 1997 (With R.M. Lynch and J. M Woodley) Process design for the oxidation of fluorobenzeneto fluorocatechol by Pseudomonasputida. J. Biotechnol. 58, 167-175 Contents of Lilly's folder divided into two for ease of reference: offprint, correspondence, referee’s comments, drafts. D.344 D.345-D.346 (227) 1997 (With S.S. Barclay, P. Spargo, A. Pettman and J.M. Woodley) Production of Baeyer Villiger mono- oxygenase for synthetic biotransformation. Proc. 1997 I. Chem. E. Research Event, pp. 981-984. Rugby: I. Chem. E. Offprint R.K. 1998 (With (228) Woodley) Transketolase catalysed carbon-carbon bond formation: biotransformation characterisation for process evaluation and selection. Enzyme Microbiol. Technol. 22, 64-67 Mitra and J.M. Contents of Lilly’s folder divided into two for ease of reference: offprint, drafts. D.347 (229) 1998 (With D.J. Pollard, A.P. Ison and P.A Shamlou) Reactor heterogeneity with Sacchropolyspora erythraea airlift fermentations. Biotechnol. Progress 58, 453-463 Offprint only. D.348-D.350 (230) 1998 (With A. Freeman) Effect of processing parameters on the feasibility and operational stability of immobilized cells. Enzyme Microb. Technol. 23, 335-345. microbial viable Contents of Lilly's folder divided into three for ease of reference: offprint, correspondence, referee’s comment, drafts. 113 1997 1997 1996-1998 1998 1998 M.D.Lilly NCUACS150/7/06 Publications, D.1-D.366 D.351 D.352 D.353 D.354 D.355 D.356 M. (With J.M. Baeyer-Villiger characterisation Woodley) (231) 1998 Biocatalytic to reactor design. Proc. 1998 Chem. E. Research Event, pp. 446-514. Rugby: |. Chern. E. Hogan and leading Offprint only. (232) 1999 (With R.K. Mitra and J.M. Woodley) Process of aldehyde properties on transketolase- implications catalysed and Biotransformation 17, 21-36 condensations. Biocatalysis Offprint only. (233) 1999 (With S. Brocklebank and J.M. Woodley) Immobilised bond synthesis: biocatalytic stability. J. Mol. Catal. B Enzymatic, 295, 191-200 carbon-carbon transketolase for Offprint only. (234) 1999 (With S. Blayer, J.M. Woodley and M.J. Dawson) Alkaline biocatalysys for the direct synthesis of N-acetyl-D-neuraminic acid (Neu5Ac) from N-acetyl-D- glucosamine (GIcNAc). Biotech. Bioeng. 66, 131-136 Offprint only. (235) 2000 (With S.M. Heydarian, A.P. Ison and P.A. Ayazi-Shamlou) filamentous bacteria in mechanically agitated batch culture. Chem. Eng. Sci. 55, 1775-1784 Turbulent breakage of Offprint only (236) 2000 (With C.J. Hack, J.M. Woodley and J.M. Liddell) Design of a fed-batch control system for microbial hydroxylation Enzyme Microb. Technol. 26, 530-536 substrates. toxic of Offprintonly. 114 1998 1999 1999 1999 2000 2000 M.D.Lilly NCUACS150/7/06 D.357 Publications, D.1-D.366 M. (238) 2003 (With J.M. Woodley) Regiospecific a recombinant yeast producing a P4501A1-yeast reductase fused enzyme. Enzyme Microb. Technol. 33, 606-611 monohydroxylation Shimizu and naphthalene by 115 2003 Offprint only. D.358-D.361 ‘Unpublished’ c.1985-2003 Contents of folder so inscribed. D.358 (with W.K. Lang, A.N.C. Weir, G. Holt and A.T. Bull) The effects of successive mutation on the growth kinetics of Bacillus subtilis NC1B 3610 Overproducing L-Lysine c. 1985, 2003 page, Typescript draft with manuscript note from Lilly to Bull on tile 1985; correspondence, 2003 between Sheila Lilly and Bull as to whetherthe paper had been published. bibliographical reference, latest D.359-D.360 P. Mohan and A-P. (with the Engineering Environmment on the Morphology of S. eythraea Influence Ison) of c.1994 Typescript drafts with manuscript amendment, marginal emphasisetc, latest bibliographical reference, 1994. Twofolders. D.361 Untitled c.1995 Typescript bibliographical reference, 1995. draft with manuscript revision, latest D.361A ‘An Engineering Review of Bioreaction Scale up’ N.d. Typescript draft, etc for paper by P. Mohan, A.P. Ison and Lilly, latest bibliographical reference 1994. ? Unpublished. M.D.Lilly NCUACS150/7/06 116 Publications, D.1-D.366 D.362-D.366 PUBLICATIONS CORRESPONDENCE 1969-1998 D.362 Biocatalysis 1991-1992 Correspondence re reviewing papers, etc. Lilly joining the editorial board, D.363-D.364 Biotechnology and Bioengineering 1969-1997 Correspondence and papers. 2 folders. Lilly was involved with the journal as author, reviewer and associate editor. D.365 Enzyme and Microbial Technology 1991, 1997 Correspondence re review of manuscript and Board meeting. Lilly was a memberofthe editorial board. D.366 Miscellaneous shorter correspondence 1991-1998 M.D.Lilly NCUACS150/7/06 SECTION E LECTURES, E.1-E.69 E.1 E.2 E.3 E.4 E.5 E.6 ‘Periodic changes in amidase synthesis by Pseudomonas aeroginosa in continuous culture’, Society for General Microbiology, 27 September 1966 Drafts of paper by A.Boddy, P.H. Clarke andLilly, figures. Also spring term 1967 colloquia list for UCL Faculty of Medical Sciences whichlists talk by Lilly on Pseudomonas aeroginosa underthetitle ‘Oscillations in bacterial enzyme synthesis’. talk, Untitled Conference on Enzyme Engineering, Hampshire, USA, 9-13 August 1971 Engineering Foundation Research Henniker, New Manuscript draft of Lilly’s talk beginning ‘Il would like to spend the first few minutes summarising our work on immobilisation at UCL and then talking about some of our recent work’, list of participants, conference information. ‘Immobilised Enzyme Reactors, Fermentation Symposium, Kyoto, Japan, March 1972 Fourth International Typescript draft. ‘The Bioengineering of Immobilised Enzymes, Rouen, France, 1972 Incomplete manuscript drafts. Untitled manuscript fragment of talk on immobilised enzymes, lists of slides and ‘definite targets by December 1972’ Although found separately the manuscript fragment may relate to papers at E.4 Untitled manuscript fragment for paper in a session on reactor design, Second Engineering Foundation Research Conference on Enzyme Engineering, Henniker, [New Hampshire], USA, 5-10 August 1973 117 1966-1996 1966-1967 1971 1972 1972 1972 1973 M.D.Lilly NCUACS150/7/06 E.7 E.8 E.9-E.12 E.13 E.14 E.15 Lectures, E.1-E.69 Untitled manuscript notes, Foundation for Research Conferences in Second Research Conference on Catalysis, Japan, May 1974 list of slides for paper at Chemistry, Osaka, Alsolist of participants and conference schedule. ‘Enzyme Technology - End of the Beginning’, Institution of Chemical Engineers Congress on Advances in Enzyme and Membrane Technology, London, 12 May 1977 Manuscript draft of Lilly’s paper, conference programme, etc. ‘Immobilzed Enzyme Reactors’, First European Congress on 25-29 September 1978 Biotechnology’, Switzerland, Interlaken, Typescript draft, photographs, correspondencerelecture, programme, etc. Four folders. See also H.14. ‘Developments in Biocatalysis’, plenary lecture, Achema Congress, 22 June 1979 Incomplete typescript draft. ‘Applications of immobilized enzymes/ cells - a survey’, Nordforsks and cellsystems and processes’, Lund, Sweden, 13-14 May 1980 ‘Immobilized in enzyme- analyses seminar and application their on 118 1974 1977 1978 1979 1980 and Manuscript programme, demonstration and poster abstracts correspondence typescript draft of re lecture, Lilly’s arrangements, ‘Two-liquid Society, London, June 1982 phase biocatalytic reactors’, The Royal 1982 Typescript correspondencere preparation oflecture. lecture drafts and of published paper, M.D.Lilly NCUACS150/7/06 Lectures, E.1-E.69 E.16 E.17 E.18 E.19 E.20 Interactions between Fermentation and Protein ‘The Recovery’ Typescript draft unidentified Undated, latest bibliographical reference 1983. lecture of for occasion. ‘Two-liquid Phase Biocatalytic Reactors’, Biotechnology Colloquium, Rutgers University, New Jersey, USA, Spring 1984 Transcriptof Lilly's ‘off the cuff paper with covering letter, 18 July 1984 ‘SERC [Science and Engineering Research Council] Presentation’, 6 December 1985 Manuscript notes, transparencies, etc. ‘Presentation to Meeting at New Orleans on January 21st 1986’ Typescript notes. ‘Industrial Use of Biocatalysts for Asymmetric Synthesis’, Society of Chemical Industry Fine Chemicals Group Symposium on Asymmetric Synthesis - Prospects for Industry’, London, 20 March 1986 Manuscript and typescript draft, list of slides, programme. 119 N.d. 1984 1985 1986 1986 E.21-E.22 ‘Biocatalysis’, Research and Development Seminar ‘The Compleat Catalysis’, Unilever House, London, 9 May 1986 1986 Typescript drafts ofLilly’s presentation, programme, list of participants, published proceedings. Twofolders. E.23-E.27 ‘Biochemical Engineering - Its Contribution to Society’, Sixth Sir Harold Hartley Memorial Lecture, Royal Society, London, 20 January 1988 1967-1988 M.D.Lilly NCUACS150/7/06 120 Lectures, E.1-E.69 to deliver Invitation arrangements and arising, includingLilly's correspondence with Hartley (E.27), etc. re drafts, background material correspondence lecture, Five folders. E.28 ‘Lecture - Williamsburg’ N.d. Contents of folder so inscribed: typescript draft of lecture headed on first page ‘Fermentation’. Undated, latest bibliographical reference, 1988. E.29 Two-liquid Phase Biocatalysis: Choice of Phase Ratio’ N.d. Typescript draft of Undated, latest bibliographical reference, D.268. 7? lecture for unidentified occasion. See 1989. E.30 ‘Lecture at Tel Aviv (1991)’ 1991 Contents of folder so inscribed: manuscript notes on index cards, etc. Lilly described ‘some of our work on the design and operation of two-liquid phase biocatalytic reactors’. E.31 Typescript and manuscript lecture notes, faxes, etc 1991-1992 Relates ?to Lilly's keynote lecture at annual IChemE Research meeting, Engineering Research: its contribution to the biological industries’, January 1992. See D.283. ‘Biochemical entitled E.32 E.33 immobilized ‘Biotransformations Mosbach Symposium, 2-5 December 1992. using biocatalysts’, 1992 Transparenciesetc forLilly’s lecture. See H.50, H.51. ‘Advances in biotransformation processes’, Dankwerts Lecture, January 1993 1993 M.D. Lilly NCUACS 150/7/06 Lectures, E.1-E.69 Typescript draft, background papers, correspondence, etc. See D.298-D.300. E.34 ‘Ascona (27.2.94)’ 5pp typescript draft so titled, manuscriptlist of slides. Lilly talked ‘about biochemical engineering to illustrate the crucial part that it has played in many past and present innovations in medicine’. E.35-E.38 ‘The development of biochemical engineering science in Europe’, Plenary lecture, 1st European Symposium on Biochemical Engineering Science, Ireland, 19 September 1996 Dublin, Typescript drafts, slides, figures, etc. Four folders. E.39 ‘Biochemical Engineering’ Contents of folder inscribed Brighton’: photographs. ‘| Chem E Mtg’ - 96? illustrative material for lecture including two E.40 Biochemical Reactors’ Manuscript notes. E.41 Biochemical Reactors’ Manuscript notes. This lecture was delivered to the Biochemical Society at the University of Bath. E.42 ‘The Challenge of the Universities’ Typescript draft. 121 1994 1996 N.d. N.d. N.d. N.d. M.D.Lilly NCUACS150/7/06 Lectures, E.1-E.69 E.43 ‘The Use of Immobilized Enzymesin Reactors’ Typescript draft. E.44-E.58 Unititled lecture notes and drafts Although these notes and drafts lack formal titles the topics are sometimes identified by Lilly in the opening paragraph, for example advancesin biotransformation at E.50 and biotechnology at E.51. Fifteen folders. 122 N.d. N.d E.59-E.69 Illustrative material for lectures and papers N.d. Eleven folders. M.D. Lilly NCUACS150/7/06 123 SECTION F SOCIETIES AND ORGANISATIONS, F.1-F.372 1968-1998 F.1 F.2-F.14 F.15 F.16-F.28 F.29 F.30-F.36 ADVISORY BOARD FOR THE RESEARCH COUNCILS (ABRC) AGRICULTURAL AND FOOD RESEARCH COUNCIL (AFRC) BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) BIOTECHNOLOGY JOINT ADVISORY BOARD (BJAB) BIOTRANSFORMATION RESEARCH ADVISORY GROUP (BRAG) COBIOTECH (ICSU INTERNATIONAL SCIENTIFIC COMMITTEE FOR BIOTECHNOLOGY) F.37 ENGINEERING FOUNDATION F.38-F.132 EUROPEAN COMMISSION (EC) F.133-F.160A EUROPEAN FEDERATION OF BIOTECHNOLOGY (EFB) F.161-F.165 EUROPEAN SCIENCE FOUNDATION(ESF) F.165A F.166-F.271 HOUSE OF LORDS SELECT COMMITTEE ON SCIENCE AND TECHNOLOGY INSTITUTE FOR BIOTECHNOLOGYSTUDIES (IBS) / INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY(IIB) F.272 INSTITUTION OF CHEMICAL ENGINEERS F.273-F.295 INTERNATIONAL ORGANIZATION FOR BIOTECHNOLOGY AND BIOENGINEERING (IOBB) M.D.Lilly NCUACS150/7/06 124 Societies and organisations, F.1-F.372 F.295A LABORATORY OF THE GOVERNMENT CHEMIST (LGC) F.296-F.322 MASSACHUSETTSINSTITUTE OF TECHNOLOGY F.323-F.333 ORGANISATION FOR ECONOMIC CO- OPERATION AND DEVELOPMENT(OECD) F.334-F.341 PUBLIC HEALTH LABORATORY SERVICE (PHLS) F.342-F.344 ROYAL ACADEMY OF ENGINEERING F.345-F.352 ROYAL SOCIETY F.353-F.367 SCIENCE AND ENGINEERING RESEARCH COUNCIL F.368-F.370 UNIVERSITY OF CAMBRIDGE F.371, F.372 WOLFSON FOUNDATION F.1 ADVISORY BOARD FOR THE RESEARCH COUNCILS (ABRC) 1992 Correspondence Opportunities discussion. and papers re ABRC_ Research Includes Biochemical Engineering’. a note by Lilly on ‘Real Opportunities in F.2-F.14 AGRICULTURAL AND FOOD RESEARCH COUNCIL (AFRC) 1991-1993 Invitation meetings. to serve, correspondence and papers re 12 folders and AFRC handbook. M.D.Lilly NCUACS150/7/06 125 Societies and organisations, F.1-F.372 In December 1991 Lilly was invited to serve as a member of a new Engineering Research Board F.15 BIOTECHNOLOGYAND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) 1993 ‘Bioprocessing in the New Biotechnology and Biological Sciences Research Council’, discussion paper by Peter Dunnill. F.16-F.28 BIOTECHNOLOGYJOINT ADVISORY BOARD (BJAB) 1992-1994 and papers re Board meetings, Correspondence workshops, etc. Thirteen folders. The BJAB wasset up in 1989 by by the Departmentof Trade and Industry and the Science and Engineering Research Council. They were subsequently joined asfull partners or observers by the other Research Councils. The BJAB’s mission was ‘to draw research base and industrial practitioners into the developmentof a strategy to innovation and to encourage the funding bodies to implement it’. successful underpin industrial Lilly accepted an invitation to serve a member of the BJAB, 1 September 1992 - 31 August 1994. F.29 BIOTRANSFORMATION RESEARCH ADVISORY GROUP (BRAG) 1996 Agendafor meeting only. Lilly was a memberof the Advisory Group. M.D.Lilly NCUACS150/7/06 126 Societies and organisations, F.1-F.372 F.30-F.36 COBIOTECH (ICSU INTERNATIONALSCIENTIFIC COMMITTEE FOR BIOTECHNOLOGY) 1990-1996 Correspondence and papers re meetings, COBIOTCH activities, relations with IOBB (qv), etc. Seven folders F.33, Papers at labelled ‘Cobiotech Steering Group Meeting 20-21 November 1994, MonteCarlo, Monaco’. F.34 were found in a file COBIOTECH wasestablished under the auspices of ICSU with the overall goals of promoting biotechnology for the benefit of mankind, of advancing research and education, and of transferring information and resourcesin thefield of technology. In 1994 Lilly formally accepted nomination to the Steering Group of COBIOTECH. F.37 ENGINEERING FOUNDATION 19$3-1997 Brief correspondence re Enzyme Engineering Award Committee. After receiving the Award himself in 1993, Lilly was appointed to the Award Committee. F.38-F.132 EUROPEAN COMMISSION (EC) 1990-1998 F.38-F.55 Human Capital and Mobility Programme/European Biochemical Engineering Network (EBEN) F.56-F.117 Framework IV F.118-F.122 Framework V F.123-F.132 Miscellaneous M.D.Lilly NCUACS150/7/06 127 Societies and organisations, F.1-F.372 F.38-F.55 Human Capital and Mobility Programme / European Biochemical Engineering Network (EBEN) 1991-1997 The European Biochemical Engineering Network was selected for funding in the European Commission Human Capital and Mobility Programme. The Advanced Centre for Biochemical Engineering, University College London was a participant. It was run by Technische Universitet Delft. F.38-F.42 Contents of Lilly's folder divided into five for ease of reference: correspondence and papers re proposal for European network. 1992-1993 Lilly's correspondents include Department of Education and Science and European colleagues. Lilly UCL colleague Peter Dunnill also appears as correspondent. F.43-F.46 Contents of Lilly’s folder divided into four for ease of reference: correspondence and papers re proposal for European network 1991-1992 Includes manuscript and typescript drafts for proposal. F.47-F.54 Miscellaneous corrrespondenceand papers found loose 1993-1997 8 folders. F.55 ‘Europe - Socrates - Erasmus’ 1994-1995 Contents of folder so inscribed: correspondence and papers. Thefirst paper in the folder inscribed ‘File - EBEN’ F.56-F.117 Framework IV 1991-1998 Correspondence and papers re biochemical engineering science activity in FrameworkIV coordinated the engineering Lilly The in science biochemical IV programme encapsulated the concept of biocatalyst- biochemical IV_ European Framework engineering science Framework Programme. M.D.Lilly NCUACS150/7/06 128 Societies and organisations, F.1-F.372 based factory process underthetitle ‘Cell Factory’. F.56-F.70 Correspondence and papers re biochemical engineering science proposal 1991-1992 In December 1991 a two-day meeting was held in the UK to discuss the lack of biochemical engineering researchin EC FrameworkIll BIOTECH programme. The outcome was a document entitled Engineering Science - Strategic Case for a Clear Focus in Framework lV’ European Commissionin January 1992. which was submitted ‘Biochemical (F.63), to the F.56 F.57 F.58 October 1991 November 1991 ‘Bio-Process Research Programme Outline Case for a Clear Focus in FrameworkIV’ N.d. Paper prepared by UK DTI [Department of Trade and Industry] Biotechnology Unit F.59-F.63 January 1992 Four folders and one bound paper (F.63) ‘Biochemical Engineering Science Strategic Case for a Clear Focusin Framework IV January 1992’ F.64 F.65 F.66 February 1992 March-April 1992 May 1992 F.67, F.68 June 1992 Twofolders. M.D.Lilly NCUACS150/7/06 129 F.69 F.70 Societies and organisations, F.1-F.372 October 1992 Photocopies of 1990 correspondence found with papers relating to FrameworkIV proposal F.71-F.77 ‘Framework IV November 92’ 1991-1993 Contents of folder so inscribed divided into seven for ease of reference: correspondence and papers re meeting on Biochemical in Framework IV, Amsterdam, The Netherlands, 9-10 November 1992 Engineering Science The aim of the meeting was to build on the December 1991 meeting, drawing up recommendations for the scientific content of a Biochemical Engineering Science programme, the recommendations to be submitted to the EC for further consideration. F.78-F.87 Correspondence and papers 1993 F.78 F.79 January 1993 ‘Biochemical for Research Programme in FrameworkIV January 1993’ Engineering Science Proposal a Bound proposal document. F.80 February 1993 IncludesLilly’s suggested form of words for a biochemical engineering science theme under the Life Sciences and Technologies line in the revised draft of Framework IV, conveyed to European Commission Directorate General for Science, Research and Development by the Departmentof Trade and Industry. the F.81 March - May 1993 M.D.Lilly NCUACS150/7/06 130 Societies and organisations, F.1-F.372 F.82 June - July 1993 Includes papers re Priorities’, 14 June 1993. ‘Dublin Meeting on BioChemical Lilly presented Science in FrameworkIV’. ‘The Case for BioChemical Engineering F.83 October 1993 F.84, F.85 November 1993 Twofolders ‘copy of the latest Commission text on Life At F.84 is a Sciences and Technologies, is proposed for inclusion in FrameworkIV’, sent to Lilly by the Department of Trade and Industry. which At F.85 is a letter from Lilly, 3 November 1993, to all participants of the Framework IV Biochemical Engineering Group enclosing a note on ‘Area No. 1 Biotechnology 1.1 Cell Factories’ setting out the ‘Objective’, ‘Implementation’ and ‘Research tasks’. On 16 November Lilly and a Dutch colleague Hans Tramper visited Brussels to have further discussions on Biochemical Engineering in FrameworkIV. F.86 December 1993 papers re Table Includes on ‘Demonstration in Life Sciences’, Brussels, 13 December 1993. IRDAC Round F.87 ‘Report of the IRDAC Round Table on "Demonstration in Life Sciences" Brussels, 13 Dcember 1993’ F.88, F.89 ‘UCL - FrameworkIV’ 1993-1994 Contents of folder so inscribed divided into two for ease of reference: includes Framework IV proposals, papers for EBEN meetings. M.D.Lilly NCUACS150/7/06 131 Societies and organisations, F.1-F.372 F.90-F.96 Correspondence and papers re Field Review Group on Cell Factories, FrameworkIV etc. 1994 Contents of untitled folder divided into seven for ease of reference: includes papers re first meeting of Group, Brussels, 28 April 1994. F.97-F.104 Correspondence Framework IV etc and papers re EBEN_ meetings, 1994 Framework Includes re Framework IV Biotechnology Event (attended by Lilly), The Hague, 26-27 November 1994. papers IV proposals and Eightfolders. These papers were found in considerable disorder. F.105-F.117 Correspondence and papers re Framework IV etc 1995-1998 Thirteen folders. Principally re European Cell Factory Conference, Lund, Sweden, 27-30 April 1997. Lilly organised this meeting with B. Hahn-Hagerdal at Lund. He gave the opening lecture. The objective of the conference was to review progress to date in achieving the aims and objectives of the Framework IV Cell Factories Programme. See F.112 for the conference programme and list of participants and F.113 for text of Lilly’s lecture. For texts prepared for publication see F.116. F.118-F.122 Framework V 1996-1997 Correspondence and papers re FrameworkV preparation. Five folders. F.123-F.132 Miscellaneous F.123 ‘European Laboratories Without Walls [ELWW] in the Framework of BPA [Biotechnology Action Programme] 1990-1997 1990 M.D.Lilly NCUACS150/7/06 132 Societies and organisations, F.1-F.372 and BRIDGE’ in respect Contents of folder so labelled: proposals for Council decisions research and development programmesin agriculture and agro-industry and the life sciences and technologies, carbon of letter from Lilly re discussions on Commission’s work with biotechnology and booklet on the ELWW. of F.124 ‘European Social Fund’ 1992 Contents of folder so labelled: project description forms, manuscript notes. F.125-F.127 European Harmonisation’ 1993-1997 Contents of folder so labelled divided into three for ease of reference: correspondence and papers re European Biotechnology Doctorate of qualifications in biotechnology. harmonisation and in F.128 ‘FITB [Flexible and Interactive Training in Biotechnology] Europe’ 1995 Contents of folder so inscribed: correspondence and papers. F.129-F.130 ‘EC - Grant Evaluation’ 1995-1996 Contents of folder so inscribed divided into two for ease of reference: correspondence and papers re biotechnology evaluation. F.131, F.132 ‘Biotechnology’s economic impact in Europe: A survey of its future role in competitiveness’ September 1994 Published report of survey undertaken by Ernst & Young and supported by the SAGB (Senior Advisory Group Biotechnology) with to ‘Biotechnology - the economic stakes 27 September 1994 and Lilly's manuscript notes on back of attendancelist. invitation meeting, London, Europe’ for Twofolders. M.D.Lilly NCUACS150/7/06 133 Societies and organisations, F.1-F.372 F.133-F.160A EUROPEAN FEDERATION OF BIOTECHNOLOGY (EFB) 1977-1997 F.133-F.136 ‘Formation of the EFB’ 1977-1984 Contents of folder so inscribed divided into four for ease of reference: of EFB, Newsletters no.5, September 1982 and no.7, September 1984. papers 1977-1978 re formation F.137-F.154 EFB Working Party on Immobilized Biocatalysts 1980-1996 Correspondence meetings. and papers including minutes of Lilly was a founding memberof the Working Party. The inaugural meeting, chaired by P.B. Poulsen, washeld in Copenhagen, 19 May 1980 F.137-F.138 1980 Twofolders. Includes ‘List of delegates and their background in the field’, August 1980 (F.138). F.139 1981 F.140-F.141 1982 Twofolders. Includes at F.141 ‘the final approved “Guidelines for the Characterization of Immobilized Biocatalysts”. F.142 1983 F.143-F.144 1984 Twofolders. M.D.Lilly NCUACS150/7/06 134 Societies and organisations, F.1-F.372 F.145-F.146 1985 Twofolders. F.147 F.148 F.149 1986 1987 1991 F.150-F.151 1992 Twofolders. F.152 F.153 1993 1994 Includes letter from the Managing Editor, Biocatalysis, 23 May 1994, re future developmentsofthe journal. F.154-F.154A 1995-1996 Twofolders. At F.154Aare Lilly’s manuscript notes and transparencies for meeting or meetings. F.155-F.158 ‘European Federation of Biotechnology EFB’ 1992 Contents of folder so inscribed divided into four for ease of reference: correspondence and papers re workshop with representatives and delegates from the European Federation of Biotechnology, Brussels, 9 April 1992. Commission European of the Includes Brussels transparencies and (F.156) for for presentation presentation by Lilly at at National M.D.Lilly NCUACS150/7/06 135 Societies and organisations, F.1-F.372 Academy of Sciences, Washington DC, 18 August 1992 (F.158). F.159-F.160 ‘EFB - Biochemical Engineering Science - NewInitiative’ 1995-1997 Contents of folder so labelled divided into two for ease of reference: correspondence and papers re EFB Section on Biochemical Engineering Science. Lilly was a memberof the Board of the Section which met for the first time on 21 September 1996 F.160A ‘Manpowerand Training Implications of the Expansion of Biotechnology Based Industries’ N.d. a workshop charged The introduction explains that the EFB commissioned in 1979-1980 the problems of education in the member countries and that the present report has been established by experts belonging to the eleven following countries: Germany, France, Greece, Ireland, Italy, the Netherlands, Norway, Poland, Switzerland and the United Kingdom. with studying Lilly was a member of the working group which produced the report. F.161-F.165 EUROPEAN SCIENCE FOUNDATION (ESF) 1992-1996 Correspondence and papers re ESF ProcessIntegration in Biochemical Engineering Programme. Five folders. Lily was a member of Committee. the Programme Steering F.165A HOUSE OF LORDS SELECT COMMITTEE ON SCIENCE AND TECHNOLOGY 1993 Lilly was invited Committee Il to submit written evidence to Sub- - Regulation of the UK biotechnology M.D.Lilly NCUACS150/7/06 136 Societies and organisations, F.1-F.372 industry andits global technology. Includes questions on which evidence was invited and drafts of Lilly's response. F.166-F.271 INSTITUTE FOR BIOTECHNOLOGYSTUDIES(IBS) / INTERNATIONALINSTITUTE OF BIOTECHNOLOGY (IIB) 1980-1996 The Institute for Biotechnology Studies was a charitable organisation established in 1983 by the Polytechnic of Central London, University College London and the University of Kent at Canterbury. The aims ofthe Institute were in biotechnology research and teaching. The management group comprised A.T. Bull University of Kent, G. Holt, Polytechnic of Central London and Lilly, University College London. multidisciplinary developments to promote The name ofthe Institute was changedto the International Institute of Biotechnology in 1989. See also B.17. F.166-F.174 ‘Consortium’ 1980-1983 Contents of ring binder so labelled: correspondence and papers re formation of a biotechnology consortium in the South East of England. F.166 Principally manuscript notes and drafts found at the front of the binder, 1981-1982, most undated F.167 November 1980 - January 1981 Includes copy of letter from the Prime Minister, Margaret Thatcher, to Lord Ironside, 20 January 1981. F.168 June - November 1981 Includes ‘A Proposal for the Formation of a Biotechnology Consortium in S.E. England’, 2pp typescript. M.D.Lilly NCUACS150/7/06 137 Societies and organisations, F.1-F.372 F.169 January - May 1982 F.170 June 1982 F.171 July 1982 Includes Trust deed for The Biotechnology Institute and Studies Centre. F.172 August-September 1982 F.173 October 1982 - January 1983 F.174 N.d. Includes photocopy of Memorandum and Articles of Association of the Institute for Biotechnological Studies Ltd. F.175 ‘Institute for Biotechnological Studies Trustees Meetings’ 1982-1983 Contents of folder so labelled: agenda and minutes of meetings. F.176-F.177 ‘Institute for Biotechnological Studies Trust Management Committee’ 1983 Contents of folder so labelled divided into two for ease of reference: agenda and minutes. F.178 ‘DT| [Department of Trade and Industry] Programme Press Release’ 1983 Contents of folder so inscribed: includes drafts, editors and others to whom pressreleasesent,etc. list of The press release was to announce joint research programme with the DTI and a number of industrial companies on developing the use of biocatalysts. M.D.Lilly NCUACS150/7/06 138 Societies and organisations, F.1-F.372 F.179 ‘PCL [Polytechnic of Central London] Correspondence’ 1983 Contents of folder so inscribed: includes carbon of Lilly’s letter, 4 August 1983, re Inner London Education Authority Review of Advanced Further Education in Inner London. F.180 ‘Efficiency Case Study I.B.S’ 1984-1986 Contents of folder so labelled: correspondence and papers re case study on the IBS. The case study was undertaken ‘to provide practical evidence of how the University’s organisational structure aids or hinders the development of an academicinitiative’. F.181 ‘|.B.S. Patenting’ 1985 Contents of folder so labelled: correspondence and papers re seeking patent protection ‘for use of benomyl to obtain unexpectedly improved production of penicillin’. F.182-F.184 ‘|.B.S. - Biennial Conference’ 1985-1988 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re organisation of the first IBS Biennial Conference. F.185-F.215 ‘Extended useof Biocatalysts Research Grant’ 1982-1989 Contents of two boxfiles This was a joint programme with the Department of Trade and Industry and Industrial Companies: Shell Research Ltd, Unilever Research, May and Baker Ltd, Glaxo Group Research Ltd, Grand Metropolitan Biotechnology, Perkin Elmer and Imperial Chemical Industries. The project, of five years duration, was started in September 1983. The programmeset out to begin to answerthe question as to why microorganismsonly synthesise useful products for a ascertain whether from an understanding of the reasons forthis their useful lives as catalysts can be extended. time and to limited F.185-F.193 General correspondence and papers 1982-1989, n.d. M.D.Lilly NCUACS 150/7/06 139 Societies and organisations, F.1-F.372 F.185 October 1982 - March 1983 F.186 April 1983 - September 1983 F.187 October 1983 - March 1984 F.188 April - June 1984 F.189 July - September 1984 F.190 October, December 1994 F.191 January - October 1985 F.192 1988-1989 F.193 N.d. F.194-F.195 ‘Institute Department of Trade and Industry Companies Grand Met’ 1983-1987 Contents of folder so inscribed divided into two for ease of reference: principally correspondence between Lilly on behalf Metropolitan Biotechnology Ltd. Institute Grand of the and F.196-F.202 Correspondence Meetings and papers re_ Industrial Liaison 1985-1988 Papers for each meeting were found in separate folders. F.196 3 April 1985 Includes transparencies. M.D.Lilly NCUACS150/7/06 140 Societies and organisations, F.1-F.372 F.197 F.198 11 April 1986 3 October 1986 F.199 27 March 1987 F.200 2 October 1987 F.201 25 March 1988 F.202 25 October 1988 F.203-F.215 Proposal and reports N.d., 1983-1989 Bound copies of documents. F.203 Proposal programme for an_ industrially-supported research N.d. With manuscript annotations. Loose copy enclosed, also with manuscript annotations. F.204 F.205 Report for at ‘Progress University College London on Thursday 1 December 1983’ Industrial Meeting Liaison 1983 With marginal emphasis. Annotated on front cover ‘Team Leader's copy’. ‘Progress Liaison University of Kent on Thursday 5 April 1984’ Industrial Report for Meeting at 1984 Annotated on front cover ‘Team Leaders copy’ M.D.Lilly NCUACS150/7/06 141 Societies and organisations, F.1-F.372 F.206 F.207 F.208 F.209 F.210 F.211 F.212 F.213 F.214 F.215 Report for ‘Progress Polytechnic September 1984’ of Industrial London Liaison at on Wednesday 26 Meeting 1984 Central Annotated on front cover ‘Team Leaders copy’. ‘Progress Report for Industrial Liaison Meeting at Perkin Elmer Limited on Wednesday 3 April 1995’ ‘Progress Report for Industrial Liaison Meeting at Glaxo Group Research Limited on Friday 4 October 1985’ Progress University College London on Friday 11 April 1986’ Industrial Liaison Report for Meeting Progress University College London on Friday 3 October 1986’ Industrial Liaison Report Meeting for at at Progress at University of Kent at Canterbury on Friday 27 March 1987’ Industrial Meeting Liaison Report for ‘Progress Report for Industrial Liaison Meeting at ICI (London) on Friday 2 October 1987’ 1985 1985 1986 1986 1987 1987 ‘Progress University College London on Friday 25 March 1988’ Industrial Liaison Report Meeting for at 1988 Progress Report for Industrial Liaison Meeting at Rhone Poulenc Ltd on Tuesday 25 October 1988’ 1988 Final Report of the Institute’s 5 year research programme - 1 September 1983 - 31 August 1988 January 1989 M.D.Lilly NCUACS150/7/06 142 Societies and organisations, F.1-F.372 F.216-F.255 General correspondence and papers 1986-1996 Includes papers for meetings of Executive Committee and Board of Management. F.216, F.217 1986-1987 Twofolders. F.218 1988 F.219-F.223 1989 Five folders. F.224-F.227 1990 Four folders. F.228-F.232 1991 Five folders F.233-F.237 1992 Five folders. F.238-F.241 1993 Four folders. F.242-F.249 1994 Eight folders. F.250-F.253 1995 Four folders. M.D.Lilly NCUACS150/7/06 143 Societies and organisations, F.1-F.372 F.254 1996 F.255 N.d. F.256-F.269 Miscellaneous papers and reports 1983-1994 F.256 F.257 Memorandum and Articles of Association Printed papers: ‘Surveyof Activities’, July 1985, ‘Research Opportunities in Biotechnology’, ‘Continuing Education in Biotechnology’, in Biotechnology’, etc ‘Information & Advisory Service In original folder. F.258 ‘1987 Policy Review’ Inscribed on title page ‘The Gospel according to David [J. Hardman])’ F.259 Two papers on the President’s Plan for the Future and Institute Development F.260 Annual General Meeting, 27 September 1990 Bound copy of agenda and papersfor meeting. F.261 ‘1990 Policy Review’ F.262 Annual General Meeting, 12 March 1991 Bound copyof agenda and papers. 1983 1985 1987 1989 1990 1990 F.263 ‘CompaniesLimited by Shares’ 1991 M.D.Lilly NCUACS 150/7/06 Societies and organisations, F.1-F.372 Directors by the Executive Paper prepared for the Secretary, David J. Hardman asdirected at the meeting of the Board on 12 March 1991, 30 July 1991. F.264 Annual General Meeting, 12 March 1992 Bound copy of agenda and papers. F.265 Annual General Meeting, 10 March 1993 Bound copy of agenda and papers for meeting F.266 Annual General Meeting, 6 June 1994 Bound copy of agenda and papers. F.267 ‘Principles of Gene Cloning and Analysis’ of A manual produced by the International Biotechnology for the COMETT programme (programme On cooperation between enterprises and universities regarding training in the field of technology), author T.A. Brown, UMIST Manchester. Institute Enclosed compliments slip is inscribed ‘For circulation to Executive Directors, 26/5/94’. 144 1992 1993 1994 1994 F.268 ‘Expression of recombinant genes’ N.d. of A manual produced by the Biotechnology for the COMETT programme (programme on cooperation between enterprises and universities regarding training in the field of technology), author M.F. Tuite, University of Kent at Canterbury. International Institute F.269 ‘International Objectives’ Institute of Biotechnology Statement of N.d. F.270-F.271 Biodiversity Ltd 1991-1992 ‘Biodiversity Ltd Overlaps with IIB’. Contents of folder so M.D.Lilly NCUACS150/7/06 145 Societies and organisations, F.1-F.372 inscribed correspondenceand papers. divided into two for ease of reference: F.272 INSTITUTION OF CHEMICAL ENGINEERS 1991-1994 Miscellaneous correspondence and papers. See also A.8-A.10. F.273-F.295 INTERNATIONAL ORGANIZATION FOR BIO- TECHNOLOGYAND BIOENGINEERING (IOBB) 1968-1997 Correspondence and papers. In a notice in Biotechnology and Bioengineering, 1975 (see F.276) Lilly as chairman explained that the |OBB was a non-profit organisation created in 1968 by Professors C.-G. Heden, |. Malek, G. Terui, H.G. Gyllenberg and E.L. Gaden Jr, and that it had been responsible for various training courses in biotechnology and bioengineering and sponsorship of many international symposia. UCL biochemical engineering was a memberfrom the late 1960s andLilly served the IOBB in a numberof capacities including a period as chairman. He was elected to the honorary membership of the IOBB in 1996, oneofthe first two honorary membersof the organisation. F.273 1968-1969 F.274 N.d. Objectives, statutes etc. F.275 1972 Programme etc for regional training course on basic research in fermentation technology, Institute of Nutrition, Cairo, 13 November-12 December 1972. M.D.Lilly NCUACS150/7/06 146 Societies and organisations, F.1-F.372 The IOBB wasoneof the sponsoring bodies. F.276 1975 Includes Statutes, January 1975 and notice on the IOBB written by Lilly, the current chairman, for Biotechnology and Bioengineering 17(2) 1975. F.277 1976-1979 Newsletters, Includes and correspondence, re dues to the International Union of Pure and Applied Biophysics, 1979. 1977 1976 and F.278 Includes minutes of meeting, 1980 and Newsletters, 1982 F.279 1983 Newsletters. F.280 1984 Includes Newsletters and Statutes. F.281 1985 Includes Newsletters. F.282 1989 Includes minutes of AGM, July 1988, circulated January 1989. F.283 ‘|.0.B.B. Directory 1989’ 1990 List of laboratories registered 1989. M.D.Lilly NCUACS150/7/06 147 Societies and organisations, F.1-F.372 F.284-F.285 1990 Twofolders. Principally membership applications. F.286 1991 Includes Newsletters and membership application. F.287 1992 Includes minutes of IOBB General Assembly, 18 August 1982. F.288-F.289 1993 Twofolders. Includes correspondence and papers re relations with other international organisations such as ICSU and COBIOTECH. F.290-F.293 1994 Four folders. Correspondence and papers re new IOBB Statutes, |OBB Chairmanship, etc. F.294 1995 Includes correspondence and papers re relations with COBIOTECH. F.295 1996-1997 notification Includes membership of Newsletter, October 1996. IOBB, of Lilly's honorary September 1996 and IOBB election to M.D.Lilly NCUACS150/7/06 148 Societies and organisations, F.1-F.372 F.295A LABORATORY OF THE GOVERNMENT CHEMIST (LGC) 1986-1990 Correspondence and papers re The Biotransformation Club. Biotransformation by The the Biotechnology Research Group of the Laboratory of the Government Chemist. research establishment of the Department of Trade and Industry. Club was operated The LGC was a The rationale of the Club was that biotransformations would effect many sectors of industry and that there was a clear need for these sectors to be aware of the many opportunities that biotransformations could offer. Lilly was a memberof the Club on behalf of the UCL Departmentof Chemical and Biochemical Engineering. F.296-F.322 MASSACHUSETTSINSTITUTE OF TECHNOLOGY 1971-1982 of material for Fermentation Principally Technology courses. photocopies Lilly was a contributor. See also H.27. F.296 Fermentation Technology Course, Massachusetts Institute of Technology, Cambridge, Massachusetts, 23-27 August 1971 ‘O2 Transfer in Biological Systems... by A.E. Humphrey’. F.297-F.297A Fermentation Technology Course Massachusetts Institute of Technology, Cambridge Massachusetts, 24-28 July 1972 F.297 ‘Topic No. 6 Translation to Different Operating Scales... By: A.E. Humphrey’ The folder also includes title page only for ‘Tables and Graphs on Topic No. 5 “Mass Transfer” ... by Daniel C. Wang’. 1971 1972 M.D.Lilly NCUACS150/7/06 149 Societies and organisations, F.1-F.372 F.297A ‘Notes, Tables and Graphs on Topic No.11 “Enzyme Isolation” ... by Malcolm Lilly’ Xerox was undated but found with the papers at F.297. F.298-F.300 Fermentation Technology Course Massachusetts Institute of Technology, Cambridge Massachusetts, 30 July - 3 August 1973 1973 F.298 F.299 F.300 F.301-F.307 ‘Tables and Graphs Topic No. 5 Mass Transfer ... By: Daniel |.C. Wang’ ‘Tables and Figures Topic No. 8 Control ... By: Arthur E. Humphrey’ Instrumentation and ‘Tables and Graphs Topic No. 11 Enzyme Science and Technology ... by M.D. Lilly’ Fermentation Office Massachusetts Institute of Technology Special European Program, London, 23-27 January 1978 Technology Industrial Liaison 1978 Contents of binder labelled ‘M.D. Lilly University College London’ divided into seven for ease of reference: list of lecturers, course outlines, daily lecture schedule, lecture materials (tables and figures) and reference materials. Lecturers include Lilly and his UCL colleague Peter Dunnill. F.308-F.322 Fermentation Technology courses, Paris, 15-19 February and MIT, 2-6 August 1982 1981-1982 F.308-F.317 ‘Massachusetts Institute of Technology Industrial Liaison Program European Course Fermentation Technology’ 1982 Contents of ring bindersotitled divided into ten for ease of reference: includes lecturers, course outlines, tables and figures for course topics and reference materials. Lecturers include Lilly. M.D.Lilly NCUACS150/7/06 F.318-F.322 Societies and organisations, F.1-F.372 correspondence Contents of untitled folder divided into five for ease of reference: for Fermentation Technology course in Paris, February 1982 and summer course at MIT, August 1982, photocopy, manuscript material, etc for course or courses. arrangements re 150 1981-1982 See also H.27. F.323-F.333 ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT(OECD) 1981-1985 Correspondence and papers. In 1981 the OECD commissioneda report on International Trends and Perspectives in Biotechnology from Lilly, A.T. Bull and G. Holt. A draft report was prepared by the end of the year and discussed at a meeting of experts, Paris, 17-18 March 1982. The draft was then modified and completed for submission to OECD member governments and subsequently published. F.323 January 1981 F.324 June-August 1981 F.325 October-November 1981 F.326-F.327 December 1981 Typescript copy of the draft report. Twofolders. F.328 January-March 1982 “International Includes Note by OECD Secretariat ‘Summary of meeting on in Biotechnology” by A.T. Bull, G. Holt and M.D. Lilly, 17th- 18th March, 1982’. Perspectives Trends and M.D.Lilly NCUACS150/7/06 151 Societies and organisations, F.1-F.372 F.329-F.330 April 1982 A duplicated typescript copy of the report submitted to the OECD membergovernmentsis at F.329. Twofolders. F.331 May-December1982 Includes correspondence and papers re meeting of the OECD Committee for Scientific and Technological Policy which considered the report, 28 May 1982. F.332 1983-1985 Correspondence into languages other than English, reviews of the published report, etc. translations report re of the F.333 N.d. Includes manuscript notes and drafts. F.334-F.341 PUBLIC HEALTH LABORATORYSERVICE (PHLS) 1988-1998 In July 1988 Lilly was invited on behalf of the Secretary of State for the Department of Health and Social Security to serve aS a member of the Public Health Laboratory Service Board. In 1993 the PHLS Board established a Research and Scientific Strategy Committee (RSSC)to be responsible for developing its R&D policy and broad strategy and for up a mechanism for the assessment of R&D at the project level. Lilly was invited to join this new Committee and serve as a memberof a small Strategic Review Group under an independent Chairman. setting Lilly's initial appointment to the Board wasfor three years from 1 August 1998. This was renewedfora further three years to 31 July 1994. After that date he continued as a member of the RSSC until 1998 when he resigned for health reasons. M.D.Lilly NCUACS150/7/06 152 Societies and organisations, F.1-F.372 F.334-F.335 Correspondence and papers re invitations to serve on Board, RRSC, Strategic Review Group, thanksfor service, letter of resignation, etc. 1988-1998 Twofolders. F.336-F.341 PHLS Research and (RSSC) Scientific Strategy Committee 1995-1997 Committee papers. Some with manuscript annotation by Lilly. F.336 RSSC meeting, 27 September 1995 Bound copy of agenda and committee papers. F.337 RSSC meeting, 16 February 1996 Agenda and committee papers. F.338 RSSC meeting, 18 April 1996 Agenda, paper and minutes. 1995 1996 1996 F.339 ‘RSSC 96/17 Preliminary Analysis of PHLS R&D Activity’ 1996 F.340-F.341 RSSC meeting, 11 April 1997 Agenda and committee papers. Twofolders. F.342-F.344 ROYAL ACADEMY OF ENGINEERING 1991-1998 F.342-F.343 Correspondence and papers re public awareness of science and engineering, industrial secondment scheme 1991-1998 M.D.Lilly NCUACS150/7/06 Societies and organisations, F.1-F.372 and membership policy Twofolders. F.344 Royal Academy of Engineering Evidence to the House of Lords Select Committee on Science and Technology: Sub-Committee II on Regulation of the UK biotechnology industry and global competitiveness and Lilly contributors to the evidence. his UCL colleague Peter Dunnill were F.345-F.352 ROYAL SOCIETY F.345-F.348 ‘Roy. Soc. Report 1981’ Contents of folder so inscribed divided into four for ease of reference: correspondence and papers re preparation of report on Biotechnology and Education by the Royal Society Education Committee Biotechnology Working Group. Lilly was a memberof the Working Group. 153 N.d. 1980-1982 1981 F.349-F.351 ‘Roy Soc / House of Commons 1981/82’ 1980-1982 Contents of folder so inscribed divided into three for ease of reference: correspondence and papers re Royal Society and House of Commons Education, Science and Arts Committee inquiry into biotechnology. Lilly was a memberof the Royal Society group giving oral evidence to the Select Committee. The brief for the group is at F.350. ‘A Summary of Higher Education for Biotechnology in the United Kingdom’, January 1982. At F.351 is typescript by Lilly titled F.352 Miscellaneous correspondence and papers 1981 M.D.Lilly NCUACS150/7/06 154 Societies and organisations, F.1-F.372 F.353-F.367 SCIENCE AND ENGINEERING RESEARCH COUNCIL 1984-1996 F.353, F.354 Papers re meetings of Biotechnology Directorate Microbial Physiology Group 1984, 1986 2 folders. F.355-F.359 ‘SERC’ 1987-1993 Contents of folder so labelled divided into five for ease of reference: correspondence and papers re Biotechnology Directorate, Engineering Research Board, establishment of new Biotechnology and Biological Sciences Research Council, etc. For Lillys comments on the SERC programme in biotechnology see F.357. F.360-F.361 ‘SERC Engineering Board Strategy Advisory Panel’ 1992-1994 Contents of folder so inscribed divided into two for ease of reference: Lilly's membership of the Strategy Advisory Group, meetings, etc. correspondence and papers re_ F.362-F.367 Biochemical Engineering Link Programme 1988-1996 Correspondence and papers re management committee meetings, assessment of programmeetc. Five folders and bound volume The programmeaimed at encouraging firms to workjointly with universities and polytechnics on pre-competitive researchrelevantto industrial needs. Lilly was both a grant holder and a member of the programme’s management committee. For papers re UCL participation in the programme see C.236-C.304, C.930-C.941. M.D.Lilly NCUACS150/7/06 155 Societies and organisations, F.1-F.372 F.368-F.370 UNIVERSITY OF CAMBRIDGE 1990-1996 Correspondence and papers re Review Committee for the Institute of Biotechnology and Appointments Committee for the Director of Biotechnology. Twofolders and bound volume. Lilly was a memberof the Review Committee. F.371-F.372 WOLFSON FOUNDATION 1994 Correspondence and papers re Wolfson Renovation, Modernisation & Equipment Programme. Laboratory Twofolders. M.D.Lilly NCUACS 150/7/06 156 SECTION G CONSULTANCIES, G.1-G.157 1968-1997 On occasions Lilly consulted in partnership with his UCL colleague Peter Dunnill as Biotech Consultants. For the beginning of the partnership see G.141. G.1 ALLIED BREWERIES (UK) LTD G.2-G.4 APCEL LTD G.5-G.18 BECKMAN INSTRUMENTSINC. G.19-G.33 BEECHAM GROUP LTD/SMITHKLINE BEECHAM G.34-G.37 BRITISH GAS PLC G.38-G.42 CELLTECH LTD G.43-G.59 ELI LILLY AND COMPANY G.60 GLAXO GROUP RESEARCH LTD G.61-G.82 HERCULES LTD G.83-G.84 HUMPHREYS & GLASGOW LTD G.85 MAY & BAKER LTD G.86-G.127 MERCK SHARP & DOHME RESEARCH LABORATORIES G.127A NOVO INDUSTRI A/S G.128 G.129 G.130 PFIZER INC. RHONE-POULENC R.T.Z. CHEMICAL LTD M.D. Lilly NCUACS 150/7/06 157 Consultancies, G.1-G.157 G.131 TATE & LYLE INDUSTRIES LTD G.132-G.139 UNILEVER LTD G.140 UOP INC. G.141-G.156 WHATMANBIOCHEMICALS LTD G.157 W.R. GRACE LTD G.1 ALLIED BREWERIES (UK) LTD 1981 Correspondence and papers re advice on commercial opportunities in biotechnology. G.2-G.4 APCEL LTD 1985-1987 Correspondence project including consultancy agreements, notes of meetings and company brochures. tryptophan papers and re_ Threefolders. G.5-G.18 BECKMANINSTRUMENTSINC. 1974-1980 G.5-G.6 ‘Beckman Consulting’ and ‘Beckman Microbics’ 1974-1979 Contents offolder so inscribed divided into two for ease of including reference: consultancy agreement, visit USA, patent, etc. arrangements to correspondence papers and_ M.D.Lilly NCUACS150/7/06 158 Consultancies, G.1-G.157 G.7-G.8 ‘Beckman (USA)’ 1975-1980 Contents of folder so inscribed divided into two for ease of reference: including consultancy agreements, arrangements for visits and papersarising, etc. correspondence and_ papers G.9-G.18 Enzymic Conversion of Steroids PD & MDL - Provisional Specification Patent Feb. 1975’ 1974-1978 Contents of folder so labelled with manuscript inscription ‘(See also Beckman correspondencefile)’ divided into ten for ease of reference: correspondence and papers re patentincluding specifications. Correspondents include National Research Development Corporation, Fitzpatricks Chartered Patent Agents and Beckman Instruments Inc. Fitzpatricks acted for Beckman Instruments in the UK. G.19-G.33 BEECHAM GROUP LTD/SMITHKLINE BEECHAM 1969-1992 G.19-G.24 ‘Beecham’ and ‘Penicillin Acylase (Case Project)’ 1969-1980 Contents of folder so inscribed divided into six for ease of reference: correspondence and papers including notes of meetings. G.25-G.33 General and agreements, patent questions etc correspondence papers re advisory 1972-1992 The papers were found in considerable disorder and the presentation of the significant amount of undated material is tentative. Nine folders. G.34-G.37 BRITISH GAS PLC 1982-1994 Correspondence and papers including reports on visits, note on biotechnology and British Gas,etc. M.D.Lilly NCUACS150/7/06 159 Consultancies, G.1-G.157 Four folders. Lilly was invited to join the Research Committee in 1982, serving until 1994. G.38-G.42 CELLTECH LTD 1987-1990 Correspondence agreements, notes of meetings, technical drawings. including papers and consultancy Five folders. G.43-G.59 ELI LILLY AND COMPANY 1987-1997 In 1992 Lilly agreed to serve as a consultant in the areas of fermentation development, biocatalysis and purification for biosynthetic processes. Lilly visited research centres in the UK and USA. G.43-G.49 General correspondence and papersincluding consulting agreement, itineraries, notes and background papers for visits. 1987-1997 Sevenfolders. G.50-G.54 ‘Eli Lilly’ 1990-1993 Contents of folder so inscribed divided into five for ease of reference: background papers for meetings. G.55-G.59 Contents of untitled folder divided into five for ease of reference: and background papersfor meetings. correspondence, manuscript notes 1993-1995 M.D.Lilly NCUACS150/7/06 160 Consultancies, G.1-G.157 G.60 GLAXO GROUP RESEARCH LTD 1981-1982 Correspondence, discussionetc. consultancy agreement, notes of G.61-G.82 HERCULES LTD 1988-1991 Contents of two box folders labelled ‘Hercules’. to The papers relate research agreement between Hercules Ltd and the Institute for Biotechnological Studies / International Institute of Biotechnology Ltd, University of Kent at Canterbury, in the area of the biodegradation of chemicals. Lilly was a memberof the management group. G.61-G.66 General correspondence and papers including research agreement, reports on meetings, ‘monthly highlights’, etc. 1988-1991 These papers werefound loosein the box. Six folders. G.67 ‘Hercules’ 1989-1991 Contents proposal revised June 1989 folder so of inscribed: includes Hercules G.68-G.70 ‘Hercules’ Contents of folder so inscribed divided into three for ease of reference: background papers, manuscript notesetc. G.71 ‘University of Kent (Hercules)’ Contents of folder so inscribed: includes letter re ‘Hercules PhaseIII Consultancy’ 1989 1991 M.D.Lilly NCUACS150/7/06 161 Consultancies, G.1-G.157 G.72-G.82 Biogradation of Chemicals Progress Reports 1989-1991 G.72 G.73 G.74 G.75 G.76 G.77 G.78 G.79 G.80 G.81 G.82 ‘1.2.89 - 30.4.89" ‘1.5.89 - 31.7.89" ‘1st August 1989 - 31st October 1989’ ‘4st November 1989 to 31st January 1990’ ‘4st February - 30th April 1990’ ‘Ist May 1990 to 31st July 1990’ ‘Ist August 1990 to 31st October 1990’ ‘{st January to 31st March 1991’ ‘{st April to 30th June 1991’ ‘Ast July to 30th September 1991’ ‘4st October to 31st December 1991’ G.83-G.84 HUMPHREYS & GLASGOW LTD 1978-1980 Correspondence agreement, notes of meetings, etc. papers and including consultancy M.D. Lilly NCUACS150/7/06 162 Consultancies, G.1-G.157 Twofolders. Lilly worked together with his UCL colleague Peter Dunnill as Biotech Consultants. G.85 MAY & BAKER LTD 1977 Oneletter only revisit. G.86-G.127 MERCK SHARP & DOHME RESEARCH LABORATORIES 1985-1994 Although the papersprincipally relate to consultancy there is a little material at G.127 re proposal for support for biochemical engineering at UCL. G.86-G.101 General papers consultancy agreements, reports onvisits, etc. correspondence and_ including 1985-1991 Sixteen folders. The assignment of undated material within the sequence is tentative. G.102-G.104 ‘Merck’ 1986-1988 Contents of folder so inscribed divided into three for ease of reference: includes paper sentto Lilly for information. G.105-G.108 ‘Merck’ 1987-1990 Contents of folder so inscribed divided into four for ease of reference: information, background papersfor meetings. includes papers sent for G.109-G.112 ‘Merck’ 1987, 1990 Contents of folder so inscribed divided into four for ease of M.D.Lilly NCUACS150/7/06 Consultancies, G.1-G.157 of reference: includes papers sent for information, draft paperbyLilly and colleagues at Merck. G.113 ‘DrLilly’ Contents of a US formatfolder: ?papers made available to Lilly during visit to Merck. 163 N.d. G.114-G.126 ‘Merck Patent Problem Litigation’ 1987-1989 Contents of box folder so inscribed divided into thirteen for ease of reference. These papers werefound in considerable disorder and the presentation of undated material is tentative. Lilly's correspondence is with the lawyers Simmons & Simmons. G.127 Correspondence and papers re proposal for support from academic Merck biochemical engineering at UCL, etc development for in G.127A NOVO INDUSTRI A/S Papersre patent case. G.128 PFIZER INC. Oneletter only. 1990-1994 1972 1992 G.129 RHONE-POULENC 1988-1989 Correspondence and papersre patentlitigation. M.D.Lilly NCUACS150/7/06 164 Consultancies, G.1-G.157 G.130 R.T.Z. CHEMICAL LTD 1981-1982 Correspondence and papers re advice in respect of the research and development capability of John & E. Sturge Ltd in the field of enzyme technology. G.131 TATE & LYLE INDUSTRIES LTD 1986 Patent application and confidentiality undertaking. G.132-G.139 UNILEVER LTD 1978-1989 Correspondence agreements, notes of meetings, etc. papers and including consultancy Eight folders. Correspondence and papers at G.139 relate to patent litigation. Lilly's UCL colleague Peter Dunnill also acted as a consultant. G.140 UOPINC. 1979 re Principally consultancy agreement between UOP Process Division and Biotech Consultants (Lilly and his UCL colleague Peter Dunnill). G.141-G.156 WHATMANBIOCHEMICALS LTD 1968-1975 G.141-G.144 ‘MDL & PD Biotech Consultants’ and ‘Basically Whatmans Consultancy and Start Up with Roberts, McLennan’ 1968-1975 M.D.Lilly NCUACS150/7/06 165 Consultancies, G.1-G.157 Contents of folder so inscribed divided into four for ease of reference: correspondence and papers including setting up of Biotech consultants, consultancy agreements,etc. Correspondents include chartered accountants Roberts, McLennan& Co. G.145-G.153 ‘Whatman Board’ 1968-1971 Contents of folder so inscribed divided into nine for ease of including minutes of meetings, reports and financial papers. correspondence and reference: papers Lilly was a memberof the board of the new company. He submitted his resignation in May 1971. G.154-G.156 ‘Whatman Biochemicals - Technical Consult’ 1969-1970 Contents of folder so inscribed divided into three for ease of reference: correspondenceand papers. Much of the correspondence is between Whatman and P. Dunnill. G.157 W.R. GRACE LTD 1981-1982 Correspondence and papersincluding report by Lilly on visit: ‘Some thoughts on biotechnology activities’. M.D.Lilly NCUACS150/7/06 166 SECTION H VISITS AND CONFERENCES,H.1-H.76 1964-1998 H.14 H.2 H.3 H.4 H.5 H.6 Society Fermentation Symposium, London, 13-17 April 1964 Chemical Industry 2nd of International 1964 Abstracts of papersandlist of participants. Chemical Macromolecules, Liverpool, 21 November 1973 Symposium Society on Catalysis by 1973 Two versions of programmewith different titles for Lilly’s paper. Thetitles in the programmesare‘Industrial Scale Isolation Industrial Catalysts’. The former is crossed out and replaced in pencil with ‘Enzymesin industrial reactors. ‘Enzymes as_ of Enzymes’ and for Research Conferences in Foundation Chemistry Second Research Conference on Catalysis, Osaka, Japan, May 1974 1974 Schedule, abstracts andlist of participants. Lilly spoke on ‘The Use of Immobilized Enzymes as Catalysts’. GIM 74 Genetics of Industrial Microorganisms Second International Symposium, Sheffield, 25-31 August 1974 1974 Secondcircular and registration form, lists of authors with the titles of their papers. Centenary Weizmann Fermentations for Organic Solvents’, December 1974 Meeting Scale ‘Large Manchester, 4 1974 Programme and list of participants. International Symposium on Analysis and Control of Immobilized Enzyme Systems, Compiegne, France, 5-7 May 1975 1975 Programmeandlist of participants M.D.Lilly NCUACS150/7/06 167 Visits and conferences, H.1-H.76 H.7 Third International Conference on Enzyme Engineering, Reed College, Portland, Oregon, 3-8 August 1975 1975 Programme H.8-H.9 Table Ronde Roussel UCLAF on Molecules, Paris, 4-5 March 1976 Polymer Bound 1976 H.8 H.9 H.10-H.11 H.12 H.13 Lilly gave a paper on ‘The useof immobilized enzymesin reactors’ List of participants; information about Tables Rondes Roussel UCLAF Bound volume comprising programmeand abstracts. Conference on the Biotechnical Applications of Proteins and Enzymes on the occasion of the sixtieth birthday of President Ephraim Katzir, Kibbutz Kiryat Anavim, Israel, 23-28 May 1976 1976 Abstracts, manuscript notes on proceedings. programme, lists of participants, Lilly’s Twofolders. Lilly gave a paper on ‘A Comparison of Cells and EnzymesasIndustrial Catalysts’. Society of Chemical Industry meeting on ‘Process control and instrumentation in Fermentation’, 13 January 1977 1977 Lilly’s manuscript notes on proceedings. and Chemical Biochemical the GDR Symposium on ‘Isolation and Application of Enzymesin Food Technology and Analytics, Karl-Marx-Stadt, German Democratic Republic, 3-5 November 1977 Societies of Invitation to symposium and first announcement only of 12th FEBS Meeting, Dresden, German Democratic Republic, 2-8 July 1978. 1977-1978 Visits and conferences, H.1-H.76 International Union for Pure and Applied Biophysics Sixth International Biophysics Congress, Kyoto, Japan, 3-9 September 1978 Third Circular only. 168 1978 First European Congress on Biotechnology, Interlaken, Switzerland, 25-30 September 1978 1977-1978 Press release, announcement and call for papers,list of participants. M.D.Lilly NCUACS150/7/06 H.14 H.15 H.16 1978 1979 1979 Training Advanced and Microbiological Technology, University of Lagos, Nigeria, 19-30 October 1978 Biochemical Course on_ Bound volume of programmeand papers. An acknowledgement explains that the course was originally planned for January 1978 and wasthe result of discussions between Lilly, as President of the IOBB and the Division of Basic Science of UNESCO. Whenthe course had to be postponed to OctoberLilly was obliged to resign as international organiser and teacher. For IOBB see F.273-F.295. The Institution of Chemical Engineers Sixth Annual Meeting on Particle Growth Processes, University College London, 4-6 April 1979 This meeting was organised colleague Peter Dunnill. by Lilly and his UCL H.18 International CNRS Symposium on Immobilized Enzymes, Organelles and Cells: Biochemical and Physico-Chemical Aspects’, 23-26 July 1979, Compiegne, France Programmeand abstracts. Lilly was a member of the organizing committee and chaired a session on kinetic properties of immobilized enzyme systems. M.D.Lilly NCUACS150/7/06 H.19 H.20 H.21 H.22 H.23-H.25 Visits and conferences, H.1-H.76 Visit to the Federal Republic of Germany of a group of British research scientists including Lilly, 19-28 September 1979 Programmesofvisit in English and Germany,letter from secretary of Joint Working Party on Biotechnology, 7 September 1979, thanking Lilly for meeting the working party and agreeing to report to it on his German visit. 13th International TNO Conference on ‘Biotechnology - a Hidden The Netherlands, 27-28 March 1980 Rotterdam, Shining Future’, Past, a Programmebooklet. Conference on Immobilzed enzymes and cells and their application in analyses and processes, Lund, Sweden, 13- 14 May 1980 Lilly’s manuscript notes on proceedings. 169 1979 1980 1980 Second Eastbourne, 5-10 April 1981 European Congress’ of Biotechnology, 1981 Programmebooklet. Lilly was a memberof the Scientific Committee and gave a paperon ‘Multi-Phase Enzymic Catalysis’. First Engineering Foundation Congress on ‘Advancesin Fermentation Banff, Alberta, Canada, 7-12 June 1981 Technology’, Recovery Process 1980-1981 Correspondence lecturers, programme, abstracts, general information and _Lilly’s manuscripts notes on proceedings. arrangements, list re of Three folders. Lilly co-chaired a session on ‘Recovery of Intracellular Products’. H.26 Third International Conference on Computer Applications in Fermentation Technology’, Manchester, 31 August - 3 September 1981 1981 M.D.Lilly NCUACS150/7/06 170 Visits and conferences, H.1-H.76 Abstracts with manuscript notesbyLilly. H.27 H.28 H.29 H.30 H.31 H.32 Course Summer Massachusetts Massachusetts, USA, 2-6 August 1982 on_ Institute Fermentation of Technology, Technology, Cambridge, 1982 Correspondence and papersre arrangements. See also F.308-F.322. ‘Immobilised Cells in Biotechnology’, the Polytechnic of Central London, 27-28 January 1983 Bound volume comprising programmeand papers. Lilly spoke on Reactor design and operation. Prime Ministers Seminar on Science, Technology and Industry, 12 September 1983 Lancaster House, St James’s, London, 1983 Information, Lilly’s manuscript notes of proceedings. Colloquium on Biotechnology: Current Aspects, Rutgers University, New Jersey, USA, 3 April 1984 1984 Programme in the form of a poster advertising the colloquium. Lilly spoke on ‘Two-liquid phasebiocatalytic reactors’. Anglo-Japanese Workshop in Biotechnology, The Royal Society, London, 2 and 3 May 1984 1984 Programme, abstracts with Lilly's manuscript notes of proceedings on verso. ‘Current Trends in Production and Use of Microbial Enzymes’, Novo Industri A/S, Bagsvaerd, Denmark, 10 and 11 May 1984 1984 Programme,list of participants, Lilly’s manuscript notes of M.D.Lilly NCUACS150/7/06 171 Visits and conferences, H.1-H.76 proceedings. Lilly gave a paper on ‘Two-liquid Phase Biocatalytic Reactors’. H.33, H.34 Third European Congress on Biotechnology, West Germany, 20 August-4 September 1984 Munich, 1984 List and supplementary list of participants. Twofolders. H.35 H.36 H.37 H.37A ‘Development of Second Generation Bioreactors for the Agro-Food Industries’, Braunschweig, West Germany, 7-9 November 1984 1984 Bound volume comprising programme, papersetc. The meeting was held under the auspices of the Commission of the European Communities Biomolecular Engineering Programme. ‘Biotechnology looks to the next decade’, New Orleans, USA, 20-22 January 1986 1986 Programme,Lilly’s manuscript notes of proceedings. Lilly was co-chairman of a Seminar on Scale-up. ‘Biocatalysis in Organic Synthesis - Opportunities for Research and Industry’, Society of Chemical Industry Symposium, London, 19 June 1986 1986 Programme, abstracts. Lilly and UCL colleague Peter Dunnill gave a paper on ‘Biocatalytic Reactions Involving Water-Soluble Organic Compounds’. Workshop Warwick, 5-6 June 1986 Microbial on Production of Cis-Glycols, 1986 Invitation, programmes, Lilly’s manuscript notes, etc. M.D.Lilly NCUACS150/7/06 172 Visits and conferences, H.1-H.76 H.38 Seventh Australian Biotechnology Conference, University of Melbourne, Victoria, Australia, 25-28 August 1986 1986 Programme and participants. registration form, list of overseas Lilly gave a paper on ‘Lysine production by immobilized cells’. H.39-H.40 H.41 H.42 H.43 Eighth France, 17-22 July 1988 International Biotechnology Symposium, Paris, Correspondence re arrangements, programme, lists of participants,etc. Twofolders. Lilly particpated in a Round-table on Education. International Quest Challenges Food Williamsburg, Virginia, USA, 2-5 October 1988 Symposium Flavor and for the on_ ‘Biotechnology Industry’, Correspondencere arrangements, programme booklet. Lilly gave a paper on ‘Biochemical Engineering for Flavor and Food Production’ ‘Opportunities in Biotransformations, Society of Chemical Industry Symposium, Churchill College, Cambridge, 3-5 April 1990 Programme only. Lilly and J. Woodley gave a paperon ‘Biotransformations of poorly water-soluble organic compounds’. Meeting Anglo-lsraeli and Biotransformations, Pembroke College, Cambridge, 25-27 March 1991 Enzyme Technology on ProgrammewithLilly’s manuscript notes on verso. Lilly gave a paper on ‘The design of bioreactors for two liquid Pembroke College, Cambridge, 25-27 March 1991 phase biotransformations’, 1987-1988 1988 1990 1991 M.D.Lilly NCUACS150/7/06 H.44-H.46 H.47 H.48 H.49 Visits and conferences, H.1-H.76 NATO Advanced Study Institute on ‘Recent Advancesin Industrial Kusadasi, Turkey, 16-27 September 1991 Biotechnology, Applications of Correspondence re arrangments and arising, participants and lecturers, report to British Council, typescript of Lilly’s paper, etc. general information, lists of Lilly’s Three folders. on ‘The lectured Lilly Biotransformation organised by former PhD student of Lilly, Sukan. Processes’. and The Design Operation meeting of was F. Vardar- Invitations declined Engineering ‘British Contemporary Museum, London, 27-28 June 1992 History British Since the War’, Conference, Institute of Science Letter from organiser, programme,abstracts etc. Lilly gave a paper on biotechnology. International Ninth Exposition Century, Crystal City, Virginia USA, 16-21 August 1992 Symposium the Biotechnology Biotechnology ‘Harnessing for and 2ist Final programme etc. H.50-H.51 Mosbach Symposium on Biochemical Technology, Lund, Sweden, 2-5 December 1992 Abstracts, etc. Twofolders. gave Lilly immobilised biocatalysts’. paper a on ‘Biotransformations using 173 1990-1992 1991-1992 1992 1992 1992 H.52-H.59 ‘Turkey’ 1992-1995 Contents of folder so inscribed divided into eight for ease M.D.Lilly NCUACS150/7/06 174 Visits and conferences, H.1-H.76 of reference: correspondence and papers. from arising correspondence Includes 1991 NATO Advanced Study Institute (H.44-H.46), and re collaboration betweenInternational Institute of Biotechnology (UK) with Ege Biotech-Enzyme network of the Med-Campus programmeof the European Commission (coordinated in Turkey), international courses held in Turkey in whichLilly participated, etc. University, Turkey, Izmir, the H.59A ‘Visit to TAU [Tel-Aviv University] 1993’ 1993 Papers re visit in connection with joint UCL / Tel-Aviv University research project in biotechnology. Includes programme for Biochemical University, 19-20 May 1993. Engineering and Biotechnology, Joint Advanced Course on Tel-Aviv gave Lilly a Fermentation’. paper on ‘Engineering Aspects of For UCL/Tel Aviv University collaboration see C.955- C.963A. H.60 H.61-H.63 1993 1994 and Med Campus Course ‘Application of Biotechnologies in Food University Biotechnology Centre, Izmir, Turkey, 6-10 September 1993 Industries’, Chemical Ege Bound volume oflecture notes. Manuscript notes by Lilly are enclosed between pp218 and 219. lectured Lilly Biotransformations for Chemical Synthesis’. ‘Design and on Operation of Engineering Foundation Conference Recombinant DNA Biotechnology Biological and Engineering Sciences, Deauville, France, 26-21 October 1994 Ill The Integration of Correspondence re arrangements, programme, abstracts, typescriptof Lilly’s paper. Three folders. A paperbyLilly and colleagues was given on ‘The Impact of rDNA Technology on Enzymic Carbon-carbon Bond Synthesis’. M.D.Lilly NCUACS150/7/06 175 Visits and conferences, H.1-H.76 H.64-H.66 Med Campus Programme, Turkey, 1995 1994-1995 Contents of untitled folder divided into three for ease of reference: correspondence and papers re this European Commission Biotech-Enzyme. Includes correspondence re international meetings in Turkey in which Lilly participated. programme’ Project H.67-H.70 International Symposium on ‘Selectivity in Basic and Applied Organic Chemistry’, Jerusalem, Israel, 27-31 August 1995 1995 H.71 H.72 H.73-H.74 Correspondence re arrangements, poster, programme and abstracts,etc. Four folders. Lilly gave a plenary lecture on ‘Carbon-carbon bond synthesis: preparation and useof transketolase’. ‘Recent Advances in Fermentation Technology’, Society of Industrial Microbiology Conference, San Diego, California, USA, 4-7 November 1995 Programme, manuscript notes of proceedings. Biocatalysis: Making it Happen’, ‘Industrial ‘96 Conference and Exhibition’, UMIST, Manchester, 20-21 February 1996 InBio Programme etc. Tenth Australia, 25-30 August 1996 International Biotechnology Congress, Sydney, Correspondencere arrangements, programmes, etc. Twofolders Lilly agreed to be co-chair of a symposium on integrated bioprocessors with B. Buckland. In the end uncertainty about his health prevented him from travelling to Sydney. 1995 1996 1994-1996 M.D.Lilly NCUACS150/7/06 176 Visits and conferences, H.1-H.76 H.75 European Cell Factory Conference, Lund, Sweden, 27-30 April 1997 1997 Book of abstracts. Lilly was an organiserof the meeting. H.76 Shorter correspondence and papers re conferences 1997-1998 Includes call for papers for Second European Symposium on Biochemical Engineering Science, Porto, Portugal, 16- 19 September 1998. Lilly was hoping to attend this meeting but died in Maythat year. M.D.Lilly NCUACS150/7/06 177 SECTION J CORRESPONDENCE,J.1-J.22 1966-1998 J.1-J.5 GENERAL CORRESPONDENCE J.6-J.22 REFERENCES AND RECOMMENDATIONS J.1-J.5 GENERAL CORRESPONDENCE 1966-1998 J.1 J.2 J.3 J.4 J.5 1966-1969 1970-1979 1983-1989 1990-1991 1992-1998 J.6-J.22 REFERENCES AND RECOMMENDATIONS 1968-1998 J.6-J.12 J.13-J.16 J.17-J.22 Appointments and promotions Grant applications Fellowships and awards J.6-J.12 Appointments and promotions 1968-1998 J.6 J.7 1968, 1984 1991 M.D.Lilly NCUACS150/7/06 178 Correspondence, J.1-J.22 J.8 J.9 J.10 J.11 J.12 1992 1993 1994-1995 1996 1997-1998 J.13-J.16 Grant applications J.13-J.15 Science Research Council / Science and Engineering Research Council J.13 J.14 J.15 J.16 1970-1976 1983 1984 Other J.17-J.22 Fellowships and awards 1970-1992 1970-1984 1989-1992 1991-1996 J.17-J.19 Fellowship Engineering 3 folders. of Engineering / Royal Academy of 1992-1996 M.D. Lilly NCUACS150/7/06 179 Correspondence, J.1-J.22 J.20-J.21 Royal Society 1991-1992 2 folders. J.22 Other 1994-1996 M.D.Lilly NCUACS150/7/06 INDEX OF CORRESPONDENTS AARON, Stuart W. ABBOTT LABORATORIES ABER INSTRUMENTS LTD ACADEMIC PRESSINC. ACEVEDO, Fernando 180 C.237, C.240, C.264, C.816 See also C.239, C.242, C.244 C.771, C.773 C.267, C.268, C.276, C.292 D.166, D.169, D.174, D.237, D.239 F.293 ADVISORY BOARD FOR THE RESEARCH COUNCILS F.1, J.7 AGRICULTURAL AND FOOD RESEARCH COUNCIL F.2-F.14, F.359 ALFA-LAVAL ENGINEERING LTD C.44, C.120, C.968 ALLEN, Sir Geoffrey ALLIED BREWERIES (UK) LTD ALLSOP, Richard E. ALONSO, Francisco José VILIESID AMERICANINSTITUTE OF CHEMICAL ENGINEERS APCEL LTD APPLIED MICROBIOLOGY AND BIOTECHNOLOGY ARCHIBALD, Peter ASENJO,Juan A. ASENJO, Barbara A. ANDREWS- ASHLEY,Mike J. ASHWORTH, John Michael BAGLEY,E. BAILEY, JamesE. BAILLIE, Wensley G. HAYDON- C.237-C.239, F.56, F.65, F.78 See also C.60, C.82, C.930, F.73, F.185 G.1 C.564 C.871, J.3 D.62 G.2-G.4 D.266 C.758 D.327, F.49, H.61 C.758 C.236 C.20 C.237, C.238 C.893 F.171, F.218, F.224, F.231 See also C.50, F.236, F.244, F.251- F.253 BAKER, Raymond See C.186 M.D.Lilly NCUACS150/7/06 181 Index of correspondents BALASINGHAM, Kangathevy BALL, Christopher BALSTON, A.E. BARBER, Michael BARCLAY,Scott S. BATCHELOR, F.R. BAYER AG BECKMANINSTRUMENTSINC BEECHAM GROUP LTD BEECHAM PHARMACEUTICALS BEECHAM RESEARCH LABORATORIES BELL, Geoffrey H. BIDE, Sir Austin BIOCATALYSIS BIOCATALYSTS LTD THE BIOCHEMICAL SOCIETY BIOCHEMIE BIOCHIMICA ET BIOPHYSICA ACTA BIOPROCESS ENGINEERING BIORESEARCH IRELAND BIOTECHNOLOGY AND BIOENGINEERING BIOTECHNOLOGYAND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) C.759, D.92 C.886 G.141, G.153 C.371 See C.670, C.761 C.388 C.758 G.5-G.8, G.13-G.16 G.19-G.33 C.47, C.237, C.238, C.242, C.244, C.245, C.306, C.393, C.775, C.943, = also C.236, C.241, C.264 C.388-C.390, C.391, C.775, D.81 C.770 C.49 D.362, F.149, F.151, F.153 F.195 F141 D.112 D.86, D.89, D.90, D.92, D.94, D.113, D.133, D.142 D.318 F.82 C.814, D.73, D.101, D.108, D.110, D.111, D.117, D.125, D.127, D.130, D.133, D.136, D.162, D.173, D.235, D.236, D.242, D.264, D.269, D.270, D.278, D.304, D.363, D.364 C.125, C.195-C.201, C.298, C.300, C.760, C.860, C.932, C.962, F.99, F.110 See also C.182, C.183 M.D.Lilly NCUACS150/7/06 182 Index of correspondents BIOTECHNOLOGY COMPUTER SYSTEMSLTD C.895-C.905 BIOTECHNOLOGY DIRECTORATE See SCIENCE AND ENGINEERING RESEARCH COUNCIL BIOTECHNOLOGYJOINT ADVISORY BOARD (BJAB) F.16-F.28 BIOTECHNOLOGY LETTERS D.213 BIOTRANSFORMATION RESEARCH ADVISORY GROUP F.29 BIRCH, John R. BIRNBAUM, Staffan C.237, C.830 D.330 BLAKEBROUGH, Norman C.321, C.786, C.827 BLANCH, Harvey W. BLAYER, Simone BLOXHAM, David P. BOEHRINGER CORPORATION (LONDON) LTD BOSSE, MichaelA. BRAUER, H. BRENCH, Alan BRESLAU, Barry R. BRIDGEWATER, John BRIGHT,Harold J. H.23 C.762 G.41 D.28 C.471 D.318 G.135, G.137 C.734 D.306 C.763 BRITISH BIO-TECHNOLOGYLTD C.237, F.65 BRITISH COUNCIL BRITISH GAS PLC BRITISH PETROLEUM COMPANYLIMITED BRITISH TECHNOLOGY GROUP BROOKES, lan K. BROWNE, Cedric H. C.786, C.795, C.812, C.813, C.827, C.828, C.829, C.831, C.863, C.867, C.886, C.957, C.959, C.961, F.168, H.45, H.54 C.48, G.34-G.37 C.770, C.824 C.943 D.229, D.231, D.241 G.37 M.D.Lilly NCUACS150/7/06 183 Index of correspondents BUCHHOLZ,Klaus BUCKE, Chris BUCKLAND, Barry Christopher lan BULL, Alan Thomas BU’LOCK, John D. BURLIN, T.E. BUSHELL,Michael E. BUTTERWORTH PUBLISHERS CABRAL, Joaquim M.S. CARLEYSMITH, Stephen Wardle CARREA, Giacomo CARRINGTON, T.R. CARVER, Claire J.L. F.140 F.150 See also C.769 C.471, C.710, C.717, C.723, C.770- C.774, C.863, C.970, D.160, D.286, D.289, D.290, F.246, F.248, G.87, G.88, G.92, G.98, G.102, G.105, H.73, H.74, J.10 See also D.288, G.95 C.337, C.338, D.358, F.167-F.169, F.171-F.173, F.192, F.216, F.228, F.233, F.243-F.245, F.254, F.271, H.52 See also C.830, F.145 D.213, F.142 F.180 C.369, C.370 D.262 F.38, F.39, F.56, F.65, F.82, F.103, F.128 See also C.183, F.74, F.150, H.56 C.471, C.951, D.290 See also C.264, C.516 C.231 C.47 See MacLEOD CASSON CONDER PARTNERSHIP (Architects) C.89, C.94, C.94A, C.97, C.103, C.107 CATTERALL, Peter CELADA, Franco CELLTECH LTD H.48 F.125 C.237, C.544, C.830, C.906, C.907, G.38-G.42, J.5 CELLTECH THERAPEUTICS LTD C.516 CHARITY COMMISSION F.169, F.170, F.173 M.D.Lilly NCUACS150/7/06 184 Index of correspondents CHAUDHARY,Subhash C. C.241, C.244, C.253, C.264, C.299, C.907 See also C.242, C.258, C.269, C.275 CHEETHAM, Peter Samuel James C.778, F.141, F.142, F.154 CHEMICAL ENGINEERING SCIENCE CHEMIE INGENIEUR TECHNIK CHIBATA,Ichiro CHRISTY, Charles CHUA,Miranda CIBA-GEIGY FELLOWSHIP TRUST CLARKE, Patricia Hannah CLARKSON, Brian L. COBIOTECH COCKCROFT,Vic COCKSHOTT,Andy R. COLEMAN, R.F. COLLINS, Anne Marguerite D.306 D.123, D.124 D.174, D.329, E.11 C.339, C.340, C.429, C.944 C.779 J.16 C.335, D.3, D.214, D.215 See also F.170, F.223 G.37 F.30 F.114 G.48, G.58, G.59 C.157, F.186 See also C.49 C.781 COMMISSION OF THE EUROPEAN COMMUNITIES F.38-F.132, F.145 COONEY, CharlesL. CORFIELD, J.R. CORNISH, Alan R.H. CORRIEU, G. CRIPPS, Roger E. CROOK,Eric Mitchell CROUT,David H.G. H.73 See also F.183 C.170 See also C.166 C.470, C.965, F.52 See also C.930 F.85 C.223, C.231, C.233, C.234, C.301 D.3, D.32 See also C.829 C.196, C.197 M.D.Lilly NCUACS150/7/06 185 Index of correspondents DAINTON, Frederick Sydney, Baron DALY, William Howard DART, E.C. DAS, Kumud DAS, M.R. DAVIES, Sir David DAVY McKEE (LONDON) LTD DECKWER,W.-D. DENNIS, John S. C.63 See also C.61 C.784 F.17, F.20, F.21 C.786, D.142 F.170, F.172 See J.5 C.79, C.80, C.93, C.96-C.98, C.106, C.107, C.736 F.85 C.183, C.246, C.268, C.276, C.295 See also C.270, C.296 DERVAKOS, George A. C.787-C.789 DIXON, Keith DOELLE, Horst W. DONALD, M.B. DORDRICK,Jonathan S. DOYLE. F.P. DOYLE, Peter DROZD, Jan W. DSM RESEARCH DUARTE, J.M.C. DUNNILL, Peter C.364, C.471, C.544, C.873 F.287-F.289, F.293-F.295 See C.321 D.333 C.388, C.389 C.50, F.65, F.66, F.233, F.234 See also C.237-C.239 C.769, C.877, D.231, D.232, D.241 C.218, C.225, C.228 H.56 See also E.15 C.35, C.61, C.84, C.103, C.115, C.119, C.127-C.132, C.156, C.157, C.159, C.166, C.179, C.182, C.183, C.208, C.209, C.238, C.269, C.305, C.320, C.369, C.419, C.709, C.716, C.717, C.734, C.770, C.779, C.784, C.786, C.805, C.815, C.827, C.829, C.831, C.841, C.866, C.875, C.930 I. M.D.Lilly NCUACS 150/7/06 186 Index of correspondents C.948, D.99, D.110, D.125, D.130, D.142, D.152, D.173, D.225, F.39, F.43, F.56, F.57, F.97, G.5, G.6, G.9, G.154-G.156, J.1 See also C.12, C.125, C.168, C.170, C.176, C.239, C.790, F.295, G.84, G.127A,J.3 DUVNJAK, Zdravko DREW, Stephen W. DYER, Sir Peter SWINNERTON- EARLE,R.L. D.162 C.773 C.384 C.805 ELI LILLY AND COMPANY C.170, G.43-G.59, J.3 ELNAWAWY,Amin S. ELSDEN, Sydney Reuben ELSEVIER EXCERPTA MEDICA NORTH-HOLLAND ELSEVIER SCIENCE PUBLISHERS ELTZ, Robert W. ENFORS, Sven-Olof ENGINEERING FOUNDATION ENZYME AND MICROBIAL TECHNOLOGY E.R. SQUIBB & SONS, INC. ERTOLA, Rudolph J. EUROPEAN COMMISSION F.293 C.321 D.115 D.227 C.770, J.2 F.64 F.37, H.61 C.709, D.223, D.228, D.229, D.233, D.240, D.251, D.252, D.261, D.262, D.279, D.280, D.281, D.350, D.365, F.146 C.770, J.2 D.4, J.1 See COMMISSION OF THE EUROPEAN COMMUNITIES EUROPEAN FEDERATION OF BIOTECHNOLOGY(EFB) F.133-F.160 EUROPEAN SCIENCE FOUNDATION (ESF) F.161-F.165 EUROPEAN SECRETARIAT OF NATIONAL BIOINDUSTRY ASSOCIATIONS EVANS, Robert F.66 G.36 M.D.Lilly NCUACS150/7/06 187 Index of correspondents FAIRTLOUGH, G.H. FELLOWSHIP OF ENGINEERING FIECHTER, A. FINER, Elliot G. FISH, Neville M. FITZPATRICKS Chartered Patent Agents FLASCHEL, Erwin FLOWERS, Brian Hilton, Baron FLYNN, David Sidney G.41 C.877, J.17 C.823 F.28 See C.739 G.6, G.12-G.18 F.143, F.145, F.148 C.62 C.792 FORRESTER, KETLEY & CO. chartered patent agents G.127A FOX, Richard I. FREEMAN, Amihay FROUD, Steve FUKUI, S. FURSTOSS, Roland GADEN, Jr, Elmer L. GARCIA, Fernando GASSER, Francis GHOSE,T.K. GIST-BROCADES NV J.2 C.793-C.795, C.956, C.957, C.959, C.961-C.963, D.244, D.245, D.296, D.350, H.67 See also D.348 G.38 See E.15 C.224, C.228, C.231, C.233, C.234, C.970, F.110 C.797, C.814, D.73, D.101, D.108- D.111, D.117, D.125, D.127, D.130, D.133, D.136, D.152, D.160, D.162, D.173, D.181, D.363 See also C.770, D.79. D.95, D.107, D.177 F.149, F.151, F.153, F.154 H.39 C.785 C.471 GLAXO GROUP RESEARCH LTD C.762, F.181, G.60 GLAXO HOLDINGS PLC GOFFEAU, André C.49 C.210, F.246 M.D.Lilly NCUACS 150/7/06 188 Index of correspondents GOLDIN, Amanda GOLDSTEIN, Walter E. GOMA,G. GOODHEW,Sir Victor Henry GOODWIN, Brian C. F.66, F.68, F.71 H.23 F.98 F.171 D.16 GRAND METROPOLITAN BIOTECHNOLOGY LTD F.194, F.195 GRAY,Peter Phillip C.796-C.799, D.104, D.109, F.225, F.246, F.251, H.73, H.74, J.5 See also D.111 GREAT BRITAIN AND NORTHERN IRELAND DEPARTMENT OF EDUCATION AND SCIENCE F.38, F.80 DEPARTMENTOF SCIENTIFIC AND INDUSTRIAL RESEARCH C.321 DEPARTMENT OF TRADE AND INDUSTRY C.157, C.202-C.207, C.239, C.241, C.244-C.250, C.255, C.258, C.259, C.298, C.930, F.28, F.74, F.81, F.82, F.84, F.90, F.118, F.188, F.189, F.362-F.364 See also F.187 LABORATORY OF THE GOVERNMENT CHEMIST C.275, F.395A OFFICE OF SCIENCE AND TECHNOLOGY F.38, F.39, F.42, F.81, F.100 OVERSEAS DEVELOPMENT ADMINISTRATION F.171, F.172 PARLIAMENT HOUSE OF COMMONS C.210 HOUSE OF LORDS SELECT COMMITTEE ON SCIENCE AND TECHNOLOGY F.165A GREENHALGH, M.E. GYLLENBERG, H.G. HAGERDAHL,Barbel HAHN- F.167 See F.173 F.48, F.97, F.106-F.111, F.114, F.115 M.D.Lilly NCUACS150/7/06 189 Index of correspondents HALLING, Peter James HAMER, Geoffrey HAMM, Wolf HANSON, Jean HARBOUR, Colin HARDMAN, David J. HARTLEY, Sir Harold HEATH, Sir Edward Richard George HEDEN, Carl-Géran HERBERT,A.B. (Andy) HEWITT, Geoffrey Frederick HIGGINS, John Joseph HOARE, Michael HOBBS, Gordon Robert HOBBS, R.F. HOLT, Geoffrey HOOKER, Nigel J. TITCHENER- C.802, J.4 F.82 G.132, G.133, G.135 D.41, D.46 C.803 F.182, F.183, F.217, F.222-F.225, F.228-F.231, F.233-F.238, F.240, F.242-F.248, F.250, F.252, F.253, F.287, G.71 See also G.61, G.63, G.66 E.27 See also J.1 F.169-F.171, F.173 H.47 C.345, C.346, H.37A J.19 C.805 C.18, C.77, C.79, C.96-C.98, C.100, C.103, C.105-C.110, C.112, C.114, C.115, C.237, C.263, C.269, C.275, C.279, C.281, C.515, C.543, C.544, C.546, C.547, C.735, C.740, C.970 C.806-C.811 F.178, F.181, F.185-F.187, F.191 See also F.188-F.190 C.862, F.168, F.169, F.171, F.173, F.182, F.223-F.225, F.238, F.243, F.245, F.247, F.250, F.271 See also F.222 C.91, C.96, C.98, C.100, C.104, C.107, C.109, C.111 HORNBY, Stephen C.267 HORNE LEA & PARTNERS(Consulting Engineers) C.89, C.90, C.106 HOUGHTON MIFFLIN COMPANY D.181 M.D.Lilly NCUACS150/7/06 190 Index of correspondents HUITRON, Carlos HUMPHREY, Arthur HUMPHREYS & GLASGOW LTD HUMPHREYS, Gwyn C.812-C.814 C.186 G.83, G.84 F.56, F.57, F.59, F.61, F.64, F.66, F.71, F.72 IC] BIOLOGICAL PRODUCTS/ ICI BIO PRODUCTS AND FINE CHEMICALS (see also ZENECA BIOPRODUCTS) C.239-C.241, C.244, C.253, C.258, C.264, C.275, C.290, H.37A ICI FIBRES IC] PHARMACEUTICALS IC] SEEDS IMPERIAL CHEMICAL INDUSTRIES PLC INGEMANSSON, Torbjoern INGRAM, David J.E. INSTITUTE FOR BIOTECHNOLOGYSTUDIES(IBS) / INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY(IIB) INSTITUTE OF BIOLOGY INSTITUTE OF CONTEMPORARYBRITISH HISTORY INSTITUTION OF CHEMICAL ENGINEERS C.943 C.471 F.17 C.50, C.337, C.345, C.346, C.877, F.181, F.185-F.189, F.191 See also C.236 C.235 F.172 See also F.173 F.166-F.271 F.169 H.48 A.7-A.9, C.709, C.716, C.731, C.734, C.736, C.739, C.868, C.878, D.33, D.65, D.118, D.300, D.320, E.23, F.272 INTERNATIONAL COUNCIL OF SCIENTIFIC UNIONS (ICSU) F.273-F.295 INTERNATIONAL FOUNDATION FOR SCIENCE J.16 INTERNATIONAL ORGANISATION FOR BIOTECHNOLOGY AND BIOENGINEERING (IOBB) F.273-F.295 INTERNATIONAL UNION OF PURE AND APPLIED BIOPHYSICS(IUPAB) INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY (IUPAC) F.277 F.278 191 Index of correspondents M.D.Lilly NCUACS150/7/06 ISENBERG, DonL. ISON, Andrew Phillip J.A. KEMP & CO. Chartered Patent Agents JACKSON, Robert JANSON, Jan-Christer JANSSEN, Dick B. JANSSEN, Frank J. JENE,Quitz JENKINS, Nigel JOHN & E. STURGE LTD JOHN BROWN ENGINEERS AND CONSTRUCTORSLTD JOHN, Chris S. G.5, G.6, G.7, G.8, G.14 See also G.13 C.101, C.106-C.109, C.112, C.120, C.369-C.371, C.834, C.907 C.462-C.464, C.466-C.470, C.943, G.129, J.4 F.67 C.815 C.228, C.233, C.235 C.816 C.396, C.397 F.111 G.130 C.236 C.264 JOHN WILEY & SONS, INC. D.101, D.110, D.180, D.181 JONES, Carys WRIGLEY- JONES, Richard Rhys JOURNAL OF BIOTECHNOLOGY JOURNAL OF CELL SCIENCE JOURNAL OF GENERAL MICROBIOLOGY KARUTZ,Martin KASTNER, Gunther SCHMIDT- See C.883 C.816-C.822 D.342, D.343 D.41, D.46 D.46, D.147, D.148, D.216 See also D.214, D.215 C.218, C.225, C.231 F.73 See also F.74 KATZIR, Ephraim KATCHALSKI- C.955, C.956, C.958, F.31, F.36 KENNEDY,John F. KESHAVARZ,Tajalli KINZEL, Jerry J. D.223, D.228, D.229, D.233, D.234 C.825 G.47, G.48 M.D.Lilly NCUACS150/7/06 KLOOSTERMANIV,Jan KNIGHT,Colin S. KNOWLES, Chris J. KONECNY,J. KONINGS, W.N. KOSSEN, Nico KUNZE, Robert J. 192 Index of correspondents C.826, D.236 C.413, G.141-G.145, G.153, G.154- G.156 F.182 F.142 F.109 C.471 G.157 L.H. ENGINEERING COMPANY LTD LAGES, Ana Christina Argolo C.923, C.924 C.828, C.829, J.3 LAURENCE, Mark B. C.267, C.269, C.270, C.296 LEAK, David LEGGE, Paddy LESLIE, R.B. LEVERHULME TRUST LIGHTHILL, Sir (Michael) James LILLEY, Gerald LILLFORD, Peter J. LILLY, Sheila E. LILLY INDUSTRIES LTD LIMON-LASONY ROLDAN, Alberto Jorge LINDAHL,Ulf LINKO, Pekka LITTLECHILD, Jennifer LOWE, C.R. F.153 B.1 C.930 C.50 C.24, C.26, C.48, C.50, C.51, C.57, C.60-C.63, C.79, C.80, C.84, C.152, C.384, C.942, C.947, C.948 C.516, C.830, C.906, C.907, G.2, G.3, G.41, J.5 C.244, C.258 See C.241, C.242, C.261, C.930 C.778, D.358 C.837 C.831 F.108 F.142 C.234 See C.892 M.D.Lilly NCUACS150/7/06 193 Index of correspondents LUYBEN, Karel Ch. A.M. LYBERATOS, Gerasimos MACALONEY, Graeme McDOUGALL, Barbara M. MACLEOD,Claire J.L. MACRIS, Basil J. MARCONI, Walter MARLOW FOODS LTD MARSHALL, Carolyn MARTEN, Neil MARTIN, Juan F. MATTHEW,Gavin B. F.39-F.42, F.44, F.45, F.49, F.51, F.52, F.55, F.75, F.161-F.163, F.165 F.53 J.3 J.3 C.832, D.148 F.38, F.59 E.11 C.471 C.833, C.863 F.171 F.109 C.834, C.835 MATTHEW HALL ENGINEERING (SOUTHAMPTON) LTD C.53 MATTHEW HALL NORCAIN ENGINEERING LTD C.919 MAY & BAKER LTD MEAD RESEARCH USA MEADOW,Pauline M. MEDICAL RESEARCH COUNCIL C.78, F.181 C.396, C.397 D.48, D.148 J.4 MERCK SHARP & DOHME RESEARCH LABORATORIES C.773, C.970, G.86-G.127, J.10 See also C.54 MICHAELS, Alan S. MOORE, Eli KESHAVARZ- MOSBACH, Klaus MOSER, A. MOSQUIERA, Fernando Guillermo MUKHERJEA,R.N. MULLIN, John W. H.23 C.103, C.109, C.114 C.813, D.169, F.37 F.78, F.85 C.836 D.33 C.48, C.361 M.D.Lilly NCUACS150/7/06 MUNRO, Peter MUTH, W.L. Index of correspondents J.4 G.46-G.49 194 NATIONAL ECONOMIC DEVELOPMENTOFFICE F.168 NATIONAL RESEARCH DEVELOPMENT CORPORATION C.305-C.320, C.322, C.393-C.395, C.943, G.9-G.11, G.14 NATURE NEALE, Stella NIELSEN, Jens NOVO INDUSTRI A/S NOVO NORDISK A/S NUESCH, Jakob NUFFIELD FOUNDATION NYIRI, Laszlo OATLEY,Geoff. E. OLATUNJI, Francis O. O’NEILL, Sean P. OROS INSTRUMENTS LTD OSHIMA, Yasuji OSSEWEIJER, Patricia PACKER, Helen L. PALFREY,R.N. PALL PROCESSFILTRATION LTD PANLABS INCORPORATED PARK,R.J. PEDERSON, Sven D.30, D.259 C.513-C.515 F.50, F.51 C.709, C.710, C.814, F.140, F.143 See also G.127A C.195 F.247 F.169, F.171 C.837 C.877 C.838-C.840 C.841 C.275 D.104 F.51-F.53, F.55, F.128, F.160, J.11 See also F.114, F.162 C.465, J.11 See also C.842-C.847 C.848 C.97, C.968, J.3 C.886 C.849 C.195, C.196 M.D.Lilly NCUACS150/7/06 PERGAMON PRESS PETROV,II. PFIZER INC PFIZER LTD 195 Index of correspondents D.298-D.300 D.28 G.128 C.362, C.404, C.471, C.873, C.877, C.945 PHARMACIA BIOPROCESS TECHNOLOGY AB PINES, SeemonH. PIRT, S.J. F.65 G.127 C.803 PLENUM PUBLISHING CORPORATION D.120, D.121 PORTON INTERNATIONAL LTD POSTE, George POULSEN, Poul Berge POWELL, Keith A. PREEZ,J.C. DU PRIEELS, Anne-Marie PROCESS BIOCHEMISTRY PUHLER, A. PYE, E. Kendall QUEST INTERNATIONAL FLAVORSUSAINC. QUINTERO, Rodolfo R.T.Z. CHEMICALS LIMITED RALPH, Bernard J. REGAN, Dennis Louis REHM, H.-J. RHODES, P.M. RICHARDS, Brian C.896 C.968 F.139, F.141, F.142 C.337 F.293 F.109, F.110 C.716, D.24, D.27 D.343, F.71 D.120, D.121 See also D.175 H.41 F.293 G.130 C.798, C.853 C.850, C.851 D.266 G.38-G.40 C.237, F.65 M.D.Lilly NCUACS150/7/06 196 Index of correspondents RICHMOND,Sir Mark (Henry) RICHMOND, William RICKARD, Pamela A.D. C.170, F.64 See also F.357 C.851, C.852, J.2 C.853 ROBERTS, McLENNAN & CO. Chartered Accountants G.141-G.144 ROBERTS, Sir Derek Harry ROBERTS, Stan M. ROBINSON, Peter J. RODGERS, Peter J. ROKEM, J. Stefan ROLZ, Carlos E. ROOKE, Sir Denis Eric ROSEN, Natasha ROTHSCHILD, Nathan Mayer Victor, Baron ROWE, Peter N. ROWLANDS, Robert T. ROYAL ACADEMY OF ENGINEERING (see also FELLOWSHIP OF ENGINEERING) C.51, C.88, C.156, C.170, C.238, C.878 See also C.239, C.961, C.962 C.208, C.209, C.403, C.404, C.420, C.760, C.860, J.4 C.854 C.345 See also C.236, C.237 F.293 F.30, F.278, F.280, F.281, F.282, F.284-F.294 C.48, C.56, C.125, F.1, G.34, G.35 C.855 F.168 C.388-C.390, C.391, C.770, C.801, J.18 C.886 J.18, J.19 ROYAL SOCIETY C.956, F.72, J.20, J.21 ROYAL SOCIETY OF CHEMISTRY C.961 RUSSELL, Andrew J. C.856, G.44-G.47, G.55 SALLIS, Paul J. SANO, Yoshiki SARRA, Montserrat SASAKAWA FOUNDATION G.64 J.2 F.50, F.51 C.57 197 Index of correspondents D.3 C.47, C.237, C.246, C.258, C.390, C.391, C.393, D.81, G.25, G.26, G.30 See also C.236, C.239, C.241, C.244, G.19, G.20 C.268, C.295, C.296 H.52 F.59, F.64 C.9, C.165, C.170, C.176, C.238, C.242, C.293, C.321- C.375, C.420, C.423, C.734, C.775, C.808, C.816, C.859, C.923, C.952-C.954, C.968, F.64, F.72, F.81, F.126, F.353- F.367, J.13-J.15 M.D.Lilly NCUACS150/7/06 SAUKKONEN, JussiJ. SAVIDGE, Tom A. SAYED, Asad SAYGIN, Erdal SCHUGERL, Karl SCIENCE RESEARCH COUNCIL / SCIENCE AND ENGINEERING RESEARCH COUNCIL (including BIOTECHNOLOGY DIRECTORATE) SENDO, Takashi SHAMLOU, Parvis Ayazi SHATZMILLER, Shimon SHELL BIOSCIENCES LABORATORY C.857 D.306 H.67 C.769 SHELL INTERNATIONAL PETROLEUM COMPANYLTD C.247, C.259, C.805 SHELL RESEARCH LTD SHELL VENTURESU.K. LTD SIEFF, Marcus Joseph, Baron SIMMONS & SIMMONS SIMPSON, T.J. SINCLAIR, J.T. SKRYABIN, Konstantin SLATER, J. Howard SLATER, Nigel K.H. SMITH, Harry SMITH KLINE & FRENCH LABORATORIES C.240, C.264, C.294, C.769, C.816 See F.185, F.187, F.189, F.191 C.877 C.52 G.114 H.67 A.13 F.31, F.32, F.35, F.36 F.270, F.271 C.240, C.471 J.20 C.58, C.968 M.D.Lilly NCUACS150/7/06 198 Index of correspondents SMITH KLINE BEECHAM PHARMACEUTICALS SMITH KLINE BEECHAM PLC C.471, C.951 See also C.516 C.245, C.246, C.249, C.250, C.258- C.260, C.264, C.299, G.33 SOCIETY FOR GENERAL MICROBIOLOGY D.48, F.180 SOLA, Carles SOLANO, Armando Ochoa SPARGO,PeterL. SPIER, Raymond E. STOCKAR, Urs von STONES, Rachel STREET, Graham SUKAN, Fazilet VARDAR- SUKAN, S. Suha SUMITOMO CHEMICAL COMPANY JAPAN SUPHANTHIKRA, Manop TAMPION, J. TANNENBAUM, Steven R. TATE & LYLE GROUP RESEARCH & DEVELOPMENT THATCHER, Margaret Hilda, Baroness THOMAS, Colin R. THOMAS, Daniel THOMAS HARRIS & ASSOCIATES TIMMIS,K. F.64, F.66, F.103 C.836 C.404, C.877, C.945 See also C.364, C.760 D.251, D.252, D.261, D.262, D.279, D.280, D.281, D.350 D.234, F.145, F.146 See C.860 C.861 C.867, C.868, F.223, F.233, F.234, H.44, H.45, H.52-H.54, H.56-H.58, H.64, H.65 See also F.287 F.222, H.44, H.45, H.52-H.54, H.56- H.58, H.65, H.66 C.398-C.401 C.862-C.865 F.172 D.95 See also C.829 C.338 F.167 C.461, C.467, C.930, D.293 F.73 C.80 C.866 M.D.Lilly NCUACS150/7/06 199 Index of correspondents TRAMPER, Johannes(‘Hans’) C.964, F.72, F.75, F.82, F.88, F.98, F.144, F.149, F.153 See also H.57, F.154 TURNER, Mike K. TURNER, NicholasJ. UHLEN, Matthias UNESCO UNILEVER PLC C.427, C.540, C.541 C.418, C.969 See also C.424 See C.892 F.172 C.242, C.248, C.258 UNILEVER RESEARCH / UNILEVER RESEARCH AND ENGINEERING C.237, C.239, C.244, C.265, C.299, C.544, C.930, F.181, F.186 See also F.185, F.187, F.188, F.189, F.191 UNILEVER RESEARCH LABORATORIUM VLAARDINGEN C.240, C.295, C.471, C.930 UNIVERSITY GRANTS COMMITTEE C.24, C.376-C.387 UNIVERSITY OF CAMBRIDGE F.368-F.370 VARDAR, Fazilet VERRIPS, T. VILIESID VILLADSEN, John W.R. GRACE & CO. WANDREY,Christian WANG, Daniel I.C. WARBURTON, David WARD, John Maxim WARREN , Simon WEBB, F.C. See SUKAN F.110 See ALONSO F.81, F.85 G.157 F.109 D.181, D.235, D.236, D.242, D.264, D.269, D.270, F.318, H.27 C.872, D.92 C.377, C.404 See also C.200 D.318 C.321, D.4 M.D.Lilly NCUACS150/7/06 200 Index of correspondents WELLCOME BIOTECHNOLOGYLTD THE WELLCOME FOUNDATION LTD C.63, C.345 C.471 WHATMANBIOCHEMICALS LTD C. 318, C.413, G.141-G.156 WHEATLEY, Margaret WHELAN, W.J. WIJFFELS, Rene WILLETTS, Andrew WILLIAMS, Angela WILLIAMS, Roger WINGARD, Jr, Lemuel B. WITHOLT, Bernard WOHLGEMUTH, Roland WOLFSON FOUNDATION WOODLEY,John Michael C.875 F.30 D.324 C.233, C.234, C.404, C.760 J.7 F.108 D.99, D.101 See C.218 C.225 C.51, C.63, C.82, F.172, F.173, F.371, F.372 See also C.88 C.126, C.168, C.196, C.230, C.398, C.401, C.403, C.416, C.717, C.762, C.763, C.809, C.822, C.877, D.310, D.320, F.88, H.71 See also C.197, C.396, C.397, C.424 WORSWICK,Richard WUBBOLTS, Marcel G. WUTHRICH, K. WYETH LABORATORIESINC. F.16 C.230 F.277 C.389 WYKES, John Richard C.319, C.885 YABUSAKI, Yoshiyasu YOUNG, T. GRAY YUSUF, Helena C.398 C.321 C.886 M.D.Lilly NCUACS 150/7/06 201 Index of correspondents ZAMBIA SOCIETY FOR GENERAL MICROBIOLOGY F.291 ZENECA BIO PRODUCTS C.264, C.295, C.299, C.423, C.907 ZENECA SEEDS F.20