ABRAHAM, Edward Penley

ABRAHAM_EDWARD_PENLEY

THE ROYAL COMMISSION ON HISTORICAL MANUSCRIPTS Report on the correspondence and papers of SIR EDWARD PENLEY ABRAHAM (1913-1999) biochemist in Bodleian Library, Oxford VOLUMEI Reproduced for the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS103/2/02) by The Royal Commission on Historical Manuscripts Quality House, Quality Court, Chancery Lane, London WC2A 1HP 2002 All rights reserved No 9/02 NRA 43883 Catalogue of the papers and correspondenceof Sir Edward Penley Abraham FRS (1913 - 1999) VOLUME | General introduction Section A: Biographical Section B: University of Oxford Section C: Research and development Section D: Publications by Simon Coleman, Peter Harper and Caroline Thibeaud NCUACScatalogue no. 103/2/02 E.P. Abraham NCUACS103/2/02 1 Title: Catalogue of the papers and correspondenceof Sir Edward Penley Abraham FRS (1913-1999), biochemist Compiled by: Simon Coleman, Peter Harper and Caroline Thibeaud Description level: Fonds Date of material: 1925-2000 Extent of material: ca 2450 items Depositedin: Bodleian Library, Oxford Reference code: GB 161 © National Cataloguing Unit for the Archives of Contemporary Scientists, University of Bath. NCUACScatalogue no. 103/2/02 E.P. Abraham NCUACS103/2/02 THE COMPILATION AND PRODUCTIONOFTHIS CATALOGUE WASMADE POSSIBLE BY GRANTS FROM THE EDWARD PENLEY ABRAHAM RESEARCH FUND AND THE EDWARD PENLEY ABRAHAM CEPHALOSPORIN FUND. E.P. Abraham NCUACS103/2/02 NOT ALL THE MATERIAL IN THIS COLLECTION MAY YET BE AVAILABLE FOR CONSULTATION. ENQUIRIES SHOULD BE ADDRESSEDIN THE FIRST INSTANCETO: KEEPER OF MANUSCRIPTS BODLEIAN LIBRARY OXFORD OX1 3BG E.P. Abraham NCUACS 103/2/02 LIST OF CONTENTS Items Page GENERAL INTRODUCTION SECTION A BIOGRAPHICAL A.1-A.115 SECTION B UNIVERSITY OF OXFORD B.1-B.92 SECTION C RESEARCH AND DEVELOPMENT C.1-C.1114 SECTION D PUBLICATIONS D.1-D.288 SECTION E LECTURES AND BROADCASTS E.1-E.63 SECTION F VISITS AND CONFERENCES F.1-F.89 SECTION G SOCIETIES AND ORGANISATIONS G.1-G.90 SECTION H CORRESPONDENCE H.1-H.563 SECTION J NON-TEXT MATERIAL J.1-J.43 INDEX OF CORRESPONDENTS 10 25 31 82 111 120 135 144 192 199 E.P. Abraham NCUACS103/2/02 GENERAL INTRODUCTION PROVENANCE 5 The papers werereceived from the Sir William Dunn School of Pathology, University of Oxford, with additional biographical material from Mrs T. Mayes, Sir Edward Abraham’s niece, in summer 2000. OUTLINE OF THE CAREER OF EDWARD PENLEY ABRAHAM Edward Penley Abraham wasborn at Southampton on 10 June 1913 and educatedthere at the King Edward VI School. He won anexhibition to Queen’s College Oxford, taking a First in chemistry and acquiring a particular interest in organic chemistry. At the Dyson Perrins Laboratory in Oxford he undertook research on peptides and studied for a D.Phil. under Robert Robinson. His work included an important contribution to the study of lysozyme which was also being investigated by Howard Florey and Ernst Chain at the Sir William Dunn School of Pathology. After taking his doctorate in 1938 Abraham wasable to develophis increasing interest in biochemistry at the Biokemiska Institut, Stockholm, which he attended as a Rockefeller Travelling Fellow. He returned to England the following year and in January 1940 took up a postat the Sir William Dunn School of Pathology at Florey’s invitation. During their investigations of naturally occurring antibiotic substances, Florey and Chain had turned their attention to penicillin in 1938. After experiments on mice in the summer of 1940 yielded encouraging results, Abraham joined the work on the purification and chemistry of penicillin. In the course of this research he and Chain observed that the antibiotic was destroyed by an enzyme producedin strain of E-coli. The discovery of this enzyme, named penicillinase, proved to be of great importance to future studies of micro-organisms and antibiotic resistance. Following thefirst successful clinical trial of penicillin on humans in February 1941, Abraham playeda significant role in the elucidation of its chemical structure and in 1943, with Chain, proposed the novel beta-lactam (henceforth written B-lactam) structure with a fused two ring system. This theory wasstrongly opposed by Abraham's former supervisor, Robinson, who favoured an alternative structure. The issue was settled in 1945 when X-ray crystallographic study by Dorothy Hodgkin and Barbara Low confirmed the B-lactam structure. Although the astonishing clinical impact of penicillin would overshadowall subsequent breakthroughs in antibiotics, the discovery of Cephalosporin C by Abraham and Guy Newtonled to the appearance of a new group of B-lactam antibiotics of equal importance to medicine and of greater commercial value. A culture of the cephalosporium fungus, whose antibiotic properties werefirst discovered in E.P. Abraham NCUACS 103/2/02 6 Sardinia by Giuseppe Brétzu in 1945, reached the Sir William Dunn School of Pathology in September 1948. After initial experiments by N.G. Heatley, the production of culture fluids was turned over to the Medical Research Council's Antibiotics Research Station at Clevedonin July 1949. Abraham and his colleagues succeeded in isolating a number of antibiotic substances from the culture fluids, the one producing the results originally observed by Brétzu given the name ‘Cephalosporin N’. The discovery of Cephalosporin C, a substance detected in minute quantities in partially purified Cephalosporin N in September 1953, was epoch making. It was active against certain bacteria unaffected by penicillin, while being resistant to penicillinase and of very lowtoxicity. Cephalosporin N was shownto be a newform of penicillin and was re-named‘Penicillin N’. Despite the combined efforts of Oxford, Clevedon and the Glaxo Group there proved to be many difficulties with the production of Cephalosporin C by fermentation andit took until 1959 for Abraham and Newton to determineits chemical structure. Later that year they showedthat subtle mutations of the Cephalosporin C molecule could lead to the production of more potent antibiotics which would still be resistant to penicillinase. Work aimed at producing higher yields of the nucleus of the molecule (7-aminocephalosporanic acid or 7-ACA) continued during the early 1960s, with Glaxo and other pharmaceutical laboratories licensed by the National Research Development Corporation (NRDC) collaborating with the Dunn School. The successful outcome of this painstaking work enabled studies of semi-synthetic cephalosporins to proceed, with the drugs cephalothin and cephaloridine being introduced into medicine in 1964. The NRDC’s worldwide patenting and licensing scheme covering the cephalosporins eventually yielded huge royalties, for many years the chief source of income for the corporation. Abraham diverted the greater part of his royalty income into two trusts, the E.P. Abraham Research Fund and the E.P.A. Cephalosporin Fund, which he set up to support medical, biological and chemical research, especially at Oxford. After 1964 Abraham continued to conduct research on B-lactam antibiotics, including the biosynthesis and enzyme inactivation of penicillins and cepahlosporins, while also investigating other antibiotics such as bacilysin. He maintained a strong interest in antibiotics research abroad, and travelled extensively to visit research laboratories and give lectures such as the Rennebohm Lecture at the University of Wisconsin (1966-1967) and the Squibb Lecture at Rutgers University (1972). Abraham waselected a Fellow of the Royal Society in 1958 and became Professor of Chemical Pathology in 1964. In addition to his knighthood in 1980, his outstanding contributions in the antibiotics field brought him numerous awards, including the Royal Medal of the Royal Society (1973), a CBE (1973), the Mullard Prize of the Royal Society (1980) and several honorary degrees. Abraham also contributed to academic life in Oxford as a Fellow of Lincoln College from 1948 to 1980 (an Honorary Fellow from 1980) and as an Honorary Fellow of a number of other colleges. E.P. Abraham NCUACS 103/2/02 7 A manof exceptional modesty, Abraham wasaffectionately regarded byhis colleaguesat all levels. He remained on good terms with both Florey and Chain after their acrimonious breach and later wrote well-received articles on both scientists for Biographical Memoirs of Fellows of the Royal Society. He married Absbjérg Harung, a Norwegian, in 1939 and they had a son. Abraham died on 8 May 1999. DESCRIPTION OF THE COLLECTION The papers cover the period 1925 to 2000. The following paragraphs are intended to provide a summaryof the collection, by section, and to draw attention to items of particular interest. Further explanatory notes and cross-references are found, where appropriate in the individual sections in the catalogue. Section A, Biographical, includes a variety of material reflecting many aspects of Abraham’s personal and professionallife. A number of his school notebooks survive, along with eighteen undergraduate notebooks. There are letters of congratulation on his election to the Fellowship of the Royal Society, 1958, and on his receipt of the Royal Medal of the Royal Society in 1973, and correspondence and papers relating to other honours and awards. Included also are correspondence concerning the history of antibiotics (mostly 1990s), correspondence and papersrelating to his support of various charities and appeals later in his life, appointments diaries (1963-1992) and a sequenceof personal correspondence, 1974-1998. Section B, University of Oxford, is short. The material includes correspondence and papersrelating to the business of Lincoln College (1960-1996), of which Abraham wasa Fellow, and building work and administration at the Sir William Dunn School of Pathology (1954-1994). Other papers, chiefly concerning social and fundraising events, reflect his associations with other Oxford colleges and organisations, sometimes through donations by the Abraham Trusts. Section C, Research, presents extensive and diverse material spanning some sixty years of Abraham’s biochemical research. There are notebooks, correspondence, publications and other papers, chiefly relating to research on cephalosporins and related substances by Abraham’s team and other organisations. There are a few of his notebooks dating from his period at the Dyson Perrins Laboratory andhis early years at the Sir Willam Dunn School of Pathology; one survives from his year in Stockholm (1938/1939) as a Rockefeller Travelling Fellow. The early Dunn School notebooksinclude details of experiments on penicillin from 1940. There is significant coverage of the collaborative research with the Antibiotics Research Station of the Medical Research Council on the E.P. Abraham NCUACS 103/2/02 8 cephalosporium culturefluids in the 1950s, the work that led to the isolation of Cephalosporin C and the determination of its chemical structure. A large body of correspondence and papersrelates to the involvement, through to the 1990s, of the National Research Development Corporation in the on- going research on the cephalosporin antibiotics and their commercial exploitation, the participation of licensed pharmaceutical companies such as Squibb, and legal cases concerning cephalosporin patents in which Abraham provided expert opinion. Experimental work by Abraham’s team on a range antibiotics and related compounds, including Cephalosporin C, Bacilysin and B-lactamases, is documented bya large group of laboratory notebooks dating from 1946 to 1983. They are mostly the work of Abraham’s research assistants, though a few are in his hand. A small body of correspondence and papers relates to research on bacilysin from 1957 and there is also some scientific correspondence of a more general nature. Section D, Publications, comprises Abraham’s drafts of scientific papers, book reviews and other articles by Abraham, dating from 1956 to 1998, and editorial correspondence. Of particular interest are the drafts and correspondencerelating to his Biographical Memoirs of Fellows of the Royal Society for Howard Florey (1971) and Ernst Chain (1983). The correspondence highlights the sensitive issues Abraham had to negotiate in the preparation and drafting of the Memoirs. There are also drafts of other obituaries he wrote for Florey and Chain. Section E, Lectures and broadcasts, principally comprises drafts and correspondencerelating to public lectures given by Abraham from ca 1960 to 1993. Most lectures are on the origin and development of B-lactam antibiotics; one given at the National Portrait Gallery in 1993 surveys the discoveries of Sir Alexander Fleming. A small amount of lecture material used by Abraham for teaching is included. The papers relating to broadcasts is slight, chiefly concerning Abraham's contributions to various television and radio programmes on penicillin, the cephalosporins and the work of Howard Florey, dating from 1962 to 1991. Section F, Visits and conferences, covers the period 1955 to 1995. The material chiefly covers Abraham's participation in symposia and conferences on chemotherapy, antibiotics and, in some cases, specifically B-lactam antibiotics. On longer stays abroad he sometimes combined attendance at symposia with lectures at universities and visits to pharmaceutical laboratories. Among the visits and conferences for which significant documentation survives are the International Congressesof Chemotherapy held in Vienna, 1967 and 1983; the Interscience Conferences on Antimicrobial Agents and Chemotherapy held in Chicago, 1967 and 1981; and visit to India in January 1985 which included the Asian Congress of Pharmacology in New Delhi. Included are drafts of papers given by Abraham at symposia. Section G, Societies and organisations, presents material covering Abraham’s involvement in many British scientific organisations, including the Biochemical Society, the Chemical Society, the Society E.P. Abraham NCUACS 103/2/02 9 for General Microbiology and the Royal Society. Overseas organisations are represented by the American Academyfor Arts and Sciences and the Australian National University (John Curtin School of Medical Research). Muchof the correspondencein this section is general in nature, though there is material relating to lectures and addresses given by Abraham, such as the 5thL.P. Garrod Lecture for the British Society for Antimicrobial Chemotherapyin 1986. Section H, Correspondence,principally consists of scientific correspondence, 1944-1998, arranged by individual or country. The correspondents include somecolleagues of Abraham, such as Norman Heatley, Henry Harris and Guy Newton, research assistants and workers in Abraham’s laboratory and scientists in other institutions. The correspondence arranged by country reflects Abraham's strong interest in antibiotics research overseas and documents visits to many countries for participation in conferences and meetings. There is also a short sequence of material concerning references and recommendations. Section J, Non-text material, largely consists of photographs of Abraham, with a few of colleagues such as Guy Newton, dating from 1930-1995. Included are school photographs, portraits from Abraham’s early career and several showing him with colleagues and fellow scientists taken at conferences or functions. There are also a few lecture slides and videotapes, one recording an event at the Sir William Dunn School of Pathology, at which Abraham spoke, celebrating the 50th anniversary of the published paper on the therapeutic application of penicillin. There is also an index of correspondents. S. Coleman Bath 2002 E.P. Abraham NCUACS 103/2/02 SECTION A BIOGRAPHICAL 10 A.1-A.115 A.1-A.10 AUTOBIOGRAPHICAL AND BIOGRAPHICAL A.11-A.40 CAREER, HONOURS AND AWARDS A.41-A.66 SCHOOL AND UNDERGRADUATE NOTEBOOKS A.67-A.96 DIARIES A.97, A.98 E.P. ABRAHAM TRUSTS A.99-A.101 CHARITIES AND APPEALS A.102, A.103 HISTORY OF SCIENCE A.104, A.105 ARCHIVES AND BOOKS A.106-A.114 PERSONAL CORRESPONDENCE A.115 LIST OF PUBLICATIONS E.P. Abraham NCUACS 103/2/02 11 Biographical A.1-A.10 BIOGRAPHICAL AND AUTOBIOGRAPHICAL 1957-1998 A.1 A.2 A.3 A.4 A.5 A.6 A.7 A.8 ‘Personal reference, 1957. records’ prepared for Royal Society, latest bibliographical Abraham waselected to the Fellowship of the Royal Society in 1958. See A.20-A.22. Autobiographical account for McGraw-Hill Modern Scientists and Engineers, 1980. ‘Sir Edward Abraham and the cephalosporin and penicillin stories’, NRDC [National Research Development Corporation] publication, 1980orlater. The article was written by J.C. Cain, Managing Director, NRDC. ‘Biography’ for Central Office of Information, 1981. ‘Newantibiotic from another happy accident’. Times, 13 December 1985. ‘Portrait’ of Abraham, Oxford ‘Edward Abraham: A major figure in antibiotics’, The Biochemist, 1990. ‘Description’ of Abraham’s career at Oxford for the University’s External Relations Office, 1991. Brief biographical details for meeting of Oxford University’s Chancellor's Court of Benefactors, 1998. ‘Chance favours the prepared mind. A tribute to the work of Sir Edward Abraham andhis distinguished colleagues at the Sir William Dunn School of Pathology’. 5 December1991. See also A.13. ‘Sir Edward Abraham: An Eightieth Birthday Tribute’, Record, 1993. Lincoln College E.P. Abraham NCUACS 103/2/02 12 Biographical A.9, A.10 Entries for biographical directories, 1971-1997. 2 folders. A.11-A.40 CAREER, HONOURS AND AWARDS 1925-1999 A.11, A.12 King Edward VI School, Southampton Abraham attended the school, 1925-1932. He was subsequently a major benefactor. A.11 A.12 Swimmingcertificates, 1925-1926 Oxford & Cambridge Schools Examination Board Certificate, 1929. A.13-A.16 Correspondence with Chairman of Governors, Headmaster and others, 1991-1998. 4 folders. A.17 The Queen’s College, Oxford. Abraham was an Exhibitioner of the College, 1932-1936 where he read the Honour School of Chemistry. Correspondence and papers, 1931-1934. Letter of 20 November 1931 from the College informs Abraham of his election to an Exhibition. A.18 Rockefeller Travelling Fellowship, University of Stockholm, 1939. Abraham worked at the Biokemiska Institut Stockholm as a Rockefeller Travelling Fellow, 1938-1939. Oneletter only from the headof the institute, H. von Euler, 18 September 1939. E.P. Abraham NCUACS 103/2/02 13 Biographical A.19 Nuffield (Penicillin) Research Fellowship, Lincoln College, Oxford, 1948. Abraham was a Fellow of Lincoln College, Oxford 1948-1980, Honorary Fellow from 1980. See also A.32. Typescript note from the Rector on the terms of the Fellowship. A.20-A.22 Election to the Fellowship of the Royal Society, 1958. Letters of congratulation, 1958. In alphabetical order. Unindexed. A.20 A.21 A.22 A.23 A-J. K-Z. Unidentified and first names only. Rennebohm Lecturer of the University of Wisconsin School of Pharmacy, 1966-1967. Certificate only. Honorary membership American Pharmaceutical Association Academy of Pharmaceutical Sciences, 1967. Certificate only. A.24, A.25 Appointed Commander of the Order of the British Empire (C.B.E.), 1973. Official notification and letters of congratulations, 1972-1973. Unindexed. A.24 A.25 Notification and letters A-H. Letters J-Z. Unidentified and first namesonly. E.P. Abraham NCUACS 103/2/02 14 Biographical A.26 Honorary Fellowship, Queen’s College, Oxford, 1973. Letters from the Provost and others re election to the Honorary Fellowship, 1973. A.27-A.29 Award of Royal Medalof the Royal Society, 1973 A.27 Correspondencewith the Royal Society, 1973-1974. A.28, A.29 Letters of congratulation, 1973. In alphabetical order. Unindexed. A.28 A.29 A-M. N-W. Unidentified first namesonly. A.30 Knighthood, 1980. Newspaper-cutting only. A.31 Honorary degree, University of Exeter, 1980. Correspondence re arrangements, manuscript notes of speech by Abraham. A.32 Dinner in Abraham’s honour at Lincoln College, Oxford, 1980. Photocopy of manuscript notes for Abraham’s speech. A.33 Mullard Award of the Royal Society, 1980. Correspondencewith the Royal Society, 1980-1981. E.P. Abraham NCUACS 103/2/02 15 Biographical A.34 A.35 Correspondence re proposed nominations of Abraham for Nobel Prize, 1981, 1983 and 1997. Honorary Fellowships of Oxford Colleges, 1983, 1986. Honorary Fellowship, St Peter's College, Oxford, 1983. Letter of congratulations only Honorary Fellowship, Keble College, Oxford, 1986 Invitation declined by Abraham: ‘But some time ago | began to feel embarrassed by the number of my Honorary Fellowships and decidedthat| should notallow the list to grow if the possibility of its doing so were to arise’. A.36 Honorary degree, Oxford University, 1984. Letters of congratulation; brief correspondencere arrangements, 1983-1984. A.37 Honorary degree, University of Strathclyde, 1989. Correspondencere arrangements, 1988-1989. A.38 Honorary degree, Harvard University, 1997. Correspondenceand papers, 1996-1997. A.39 Opening of the Oxford University Pathology Support Building, 1997. Abraham officially opened the building to which he had ‘contributed so generously’, 10 October 1997. A.40 Funeral and memorial service. 1999. Includes memorial address by H. Harris as published in Oxford Magazine, Nougth Week, Hilary Term, 2000. Draft of obituary by L.D. Sabbath. E.P. Abraham NCUACS 103/2/02 16 Biographical A.41-A.66 SCHOOL AND UNDERGRADUATE NOTEBOOKS 1928-1936 A.41-A.48 King Edward VI School, Southampton, notebooks. A.41 A.42 A.43 A.44 A.45 A.46 Notebook with label ‘King Edward’s School, Southampton’ on front cover with pupil’s name ‘E. Abraham’, the subject ‘Physics’ and the date ‘Oct. 1928’. Used for experimental work. list of experimentsis on thefirst lined pageat the front. Notebook with label ‘King Edward’s School, Southampton’ on front cover with pupil’s name ‘E. Abraham’ and the subject ‘Physics’. N.d. Used for experimental work. Notebook with label ‘King Edward’s School, Southampton’ on front cover with pupil’s name ‘E. Abraham’ and the subject ‘Physics. Heat & light sound’. N.d. Used for experimental work. Notebook with label ‘King Edward’s School, Southampton’ on front cover with pupil’s name ‘E. Abraham’ and the subject ‘Physics [rest of label torn but probably indicated that the particular areas of the subject covered were magnetism and electricity]’. N.d. Used for experimental work. Notebookwith label ‘King Edward VI. School, Southampton’ on front cover with pupil’s name ‘E.P. Abraham’ and the subject ‘Physics’. N.d. Used for notes on the ‘Properties of Matter’. ‘Notebookwith label ‘King Edward VI. School, Southampton’ on front cover with pupil’s name ‘E.P. Abraham’ and the subject ‘Physics’. N.d. Used for notes on ‘The Properties of Matter’. E.P. Abraham NCUACS 103/2/02 17 Biographical A.47 A.48 ‘Notebook with label ‘King Edward VI. School, Southampton’ on front cover with pupil’s name ‘E.P. Abraham’ andthe subject‘PhysicsII’. N.d. Used for notes on magnetism andelectricity. ‘Notebookwith label ‘King Edward VI. School, Southampton’ on front cover with pupil’s name ‘E.P. Abraham’. Used for essays. Thefirst essay on pragmatism is dated at the end ‘Essay Club Winter Term 1930’. A.49-A.66 Undergraduate notebooks, The Queen’s College, Oxford. A.49 A.50 A.51 A.52 A.53 King Edward VI. School, Southampton notebook with school label on front cover obscured with new blank label inscribed ‘The Phase Rule’. ‘E.P. Abraham’ inscribedinside front cover. N.d. Used for undergraduate notes. Notebookwith ‘E.P. Abraham Queen’s College Oxford’ inscribed inside front cover. Used for ? essays on chemistry. ‘The composition of water and the relative atomic weights of oxygen and hydrogen’is dated ‘Nov. 1° 1932’. Notebook with ‘E.P. Abraham The Queen's College Oxford’ inscribed inside front cover. First page headed ‘The methods for the Used for chemistry notes. determination of vapour density’. Latest date in the text 1933 (in note on the hydrogen isotope). Notebook with ‘E.P. Abraham The Queen’s College [Oxford] 1934’ inscribed inside front cover. Used from the front for notes on ‘Isomerism’. Notebook with ‘E.P. Abraham The Queen’s College Oxford 1934’ inscribed inside front cover. Used from the front for notes on ‘The kinetic theory of gases’. E.P. Abraham NCUACS103/2/02 18 Biographical A.54 A.55 A.56 A.57 Notebook with ‘E.P. Abraham 1934’ inscribed on the front cover. Used from the front for notes on ‘The lesser known elements’ and from the back for notes on ‘Inorganic compounds’. Notebook with ‘E.P. Abraham 1934’ inscribed on the front cover. Used from the front for notes on ‘Corrosion, Passivity and the Protection of Metals’. Notebook with ‘E.P. Abraham The Queen’s College [Oxford]’ inscribed inside front cover. Used for notes on ’Oxidation and Reduction in Organic Chemistry’ from the front and on ‘Mechanism of Reactions’ from the back. Latest bibliographical reference 1934. Notebook with ‘E.P. Abraham The Queen's [College Oxford]’ inscribed inside front cover. Used from the front for notes on ‘Acids and bases (continued)’. Latest date in notes 1934. A.58 Notebook with ‘E.P. Abraham’ inscribed inside front cover. Used for notes on ‘Rubber’, ‘Ketenes’, ‘The basic properties of oxygen’, etc. Latest bibliographical reference 1935. A.59 A.60 Notebook with ‘E.P. Abraham The Queen’s College {Oxford]’ inscribed inside front cover. Used from the front for notes on ‘Relativity’, ‘The Alkaloids’, ‘Structure and Synthesis’, ‘Carbohydrates’ etc. Latest bibliographical reference 1936. Notebook with ‘Essays inscribed inside front cover. E.P. Abraham The Queen’s [College Oxford] There are essays on ‘Fermentation’, ‘The Constitution of Alcohol and Ether’, ‘Aldehydes’, Latest bibliographical reference 1932. ‘Nitrification’, Nitrogen’, etc. ‘The fixation of E.P. Abraham NCUACS 103/2/02 19 Biographical A.61 A.62 A.63 A.64 A.65 A.66 Notebookwith ‘E.P. Abraham The Queen’s College [Oxford]’ inscribed inside front cover. First page headed ‘Essays’. However, contents may be summary notes of contents of earlier notebooks perhapspreparedfor revision purposes. See A.50 for example. Latest bibliographical reference 1934. Notebook with ‘E.P. Abraham 1934’ inscribed inside front cover. Usedfor notes re practical work. First page headed ‘Quantitative Analysis’. Notebook with ‘E.P. Abraham The Queen’s College Oxford 1934’ inscribed inside front cover. Used for notes re practical work. etc.’ First page headed ‘Organic Preparations Notebook with ‘E.P. Abraham The Queen’s College [Oxford]’ inscribed inside front cover. N.d. Used for notes re practical work. Chemistry’. First page headed ‘Points in Physical Notebook with ‘E.P. Abraham The Queen’s [College Oxford]’ inscribed inside front cover. N.d. Used from both endsfor notes re practical work. First page at front headed ‘Potassium iodate’. First page at back headed ‘Gas Manipulation’. Notebookwith ‘E.P. Abraham The Queen’s [College Oxford]’ inscribed inside front cover. N.d. Used for notes re practical work. First page headed ‘Tetrahydrocarbazole’. E.P. Abraham NCUACS103/2/02 20 Biographical A.67-A.96 DIARIES 1963-1992 Appointments diaries. The sequencelacks a diary for 1970. There are two diaries for 1978. A.67 A.68 A.69 A.70 A.71 A.72 A.73 A.74 A.75 A.76 A.77 A.78 1963. 1964. 1965. 1966. 1967. 1968. 1969 1971. 1972. 1973. 1974. 1975. E.P. Abraham NCUACS 103/2/02 Biographical A.79 A.80 A.81 A.82 A.83 A.84 A.85 A.86 A.87 A.88 A.89 A.90 A.91 A.92 1976. 1977. 1978. 1978. 1979. 1980. 1981. 1982. 1983. 1984. 1985. 1986. 1987. 1988. E.P. Abraham NCUACS 103/2/02 22 Biographical A.93 A.94 A.95 A.96 1989. 1990. 1991. 1992. A.97, A.98 E.P. ABRAHAM TRUSTS 1979, 1989 A.97 A.98 Abraham established a number of charitable trusts with funds arising from the developmentof the cephalosporin antibiotics. Letter from E.P. Abraham re cephalosporin funds in reply to an enquiry from G.Wilkinson, February 1979. Letter from Kidsons chartered accountants, 20 February 1989, enclosing photocopies of Deed of Trust in respect of the E.P. Abraham Research Fund, 17 March 1967, Trust Deed in respect of the Guy Newton Research Fund, 17 March 1967, and Deed of Trust in respect of the.E.P.A. Cephalosporin Fund, 18 May 1970. A.99-A.101 CHARITIES AND APPEALS 1975-1997 Correspondence and papers re charities and appeals supported by Abraham, 1975-1997. 3 folders. E.P. Abraham NCUACS103/2/02 23 Biographical A.102, A.103 HISTORY OF SCIENCE 1976, 1994-1998 Correspondence with historians and others re the history of antibiotics, biographies of scientists etc., 1976,1994-1998. 2 folders. A.104, A.105 ARCHIVES AND BOOKS 1986-2000 Correspondence and papers re arrangements made for Abraham’s archives and booksand re related matters, 1986-2000. A.104 1986-1989. A.105 1997-2000. 2000 item is a list of the books transferred from Abraham’s home to Lincoln College, Oxford. A.106-A.114 PERSONAL CORRESPONDENCE 1974-1998 A.106-A.108 A chronological sequence of correspondence, 1974-1998. Includes replies to Abraham'sletters of congratulation. A.106 1974-1976. A.107 1979-1993. A.108 1995-1998, n.d. E.P. Abraham NCUACS 103/2/02 24 Biographical A.109-A.114 Correspondenceand papers with B.L Parry and others, 1973-1977 and n.d. 6 folders. A.115 PUBLICATIONSLIST Typescript chronologicallist of Abraham’s publications. E.P. Abraham NCUACS 103/2/02 25 SECTION B UNIVERSITY OF OXFORD B.1-B.92 B.1-B.37 WILLIAM DUNN SCOOL OF PATHOLOGY B.38-B.61 LINCOLN COLLEGE B.62-B.92 OTHER COLLEGES AND UNIVERSITY ORGANISATIONS E.P. Abraham NCUACS 103/2/02 26 University of Oxford B.1-B.37 WILLIAM DUNN SCHOOL OF PATHOLOGY 1954-1994 B.1-B.19 Invoices etc for equipment and supplies purchased by the William Dunn School, 1954. 19 folders. B.20-B.35 Correspondence and papers re the building of a major extension to the School, 1964-1975, 1980. Contents of 2 files inscribed ‘Pathology - New Building’. 16 folders. B.36 B.37 Minutes of Departmental Committee Meetings etc, 1992-1994. Miscellaneous correspondenceand papers, 1992-1994. B.38-B.61 LINCOLN COLLEGE 1960-1996 Abraham wasa Fellow of Lincoln College, 1948-1980, and a member of the College’s Finance Committee. See A.19 and A.32 for further material relating to Lincoln College. B.38 Various committee papers and other papers re general College business, 1960-1965, n.d. B.39-B.47 ‘Lincoln College Appeal’. Contents of a file so inscribed. The college organised an appeal in 1972 for the conversion of a church into a newlibrary and later sought funds for other projects. Correspondenceetc, 1972-1993. 9 folders. E.P. Abraham NCUACS103/2/02 27 University of Oxford B.48-B.57 Correspondence and papers re general business and activities of the college, 1974-1996, with a few papers 1962-1964. Included are invitations to functions and papers relating to college and committee meetings (Abraham was a memberof the Finance Committee). Included in B.53 is a 2pp manuscript draft of a speech by Abraham, [?after 1980]. 10 folders. B.58 Letter from National Research Development Corporation, with related papers, 1979. Found with papersin B.48-B.54. B.59-B.61 Copies of papers concerning applications for Junior Research Fellowshipsat Lincoln College, including accounts of research projects or proposed research, 1975. 3 folders. B.62-B.92 OTHER COLLEGES AND UNIVERSITY ORGANISATIONS 1958-1998, n.d. Arrangedalphabetically. Miscellaneous correspondenceis at B.91, B.92. B.62 Ashmolean Club 1990-1998 Abraham was a Supernumerary Member. Correspondence, mostly notices for meetings. B.63, B.64 Green College 1993-1998 Abraham wasonthe College Advisory Council. Correspondence and papers re Advisory Council meetings and various events and functions. 2 folders. E.P. Abraham NCUACS103/2/02 28 University of Oxford B.65 Keble College 1992-1996 Correspondenceetc re appointments of EPA Junior Research Fellows. B.66 Lady MargaretHall 1978-1997 Abraham waselected an Honorary Fellow of the college in 1978. Correspondence etc re Abraham’s election to an Honorary Fellowship, invitations to functions, grants to the college by EPA trusts and other matters, 1978, 1992-1997. B.67, B.68 Linacre College 1983-1996 Abraham was an Honorary Fellow of the college. The EPA Cephalosporin Fund made a donation towards a newresidential building at the college. Correspondenceetc re invitations to functions and general business. 2 folders. B.69-B.71 Natural Sciences Club 1969-1988 Abraham was a member. Papers and correspondencere meetings, functions and general business. 3 folders. B.72 Pembroke College 1988-1995 Abraham wasa Friend of Pembroke. One or both of the Abraham Trusts donated moneyto the college. Correspondenceetc re invitations to functions and general business. E.P. Abraham NCUACS103/2/02 29 University of Oxford B.73, B.74 The Queen's College 1977-1996 Abraham wasan Honorary Fellow. Correspondence re functions and general business. 2 folders. B.75 St Cross College 1983-1990 One or more of the Abraham trusts appears to have been a benefactorof the college. Correspondenceetc re invitations to functions and other business. B.76 St Hilda’s College 1984-1994 Both Abrahamtrusts were benefactors of the college. Correspondence etc mostly re funding of academic posts and functions, 1984-1994. B.77 St Hugh’s College / St Anne’s College 1995, 1997 At least one of the Abraham trusts was a benefactor of St Hugh’s College. Correspondence,mostly re invitations to functions. B.78, B.79 St Peter’s College 1987-1997 Abraham was an Honorary Fellow. The EPA Cephalosporin Fund made a donation to the college to help endow an existing Biological Sciences Fellowship. Correspondenceetc re functions and general business. 2 folders. E.P. Abraham NCUACS103/2/02 30 University of Oxford B.80-B.88 University Registry and otheroffices 1958-1998,n.d. B.80-B.85 Contentsof file inscribed ‘University Offices’. Correspondence etc with the Registrar and other offices and individuals within the University, 1958-1998, n.d. Topics covered include funding for the Sir William Dunn School of Pathology, Abraham’sreceipt of an honorary Doctor of Science degree from the University in June 1983, and various events and functions, 1958-1998. 6 folders. B.86, B.87 Contents of file inscribed ‘University Registry’. Correspondencere fundraising, events and general matters, 1977-1988. 2 folders. B.88 Contentsofa file entitled ‘Safety’. Papers and correspondence, mostly with the University of Oxford Safety Office, re safety procedures associated with work with micro-organisms, 1989-1992. B.89, B.90 Wolfson College 1982-1995 Abraham was an Honorary Fellow of the college and a Patron of its Appeal. The EPA Cephalosporin Fund made a donationto the college. Correspondence, mostly re fundraising and functions. 2 folders. B.91, B.92 Miscellaneous correspondence 1993-1997 Correspondence with various Oxford colleges, including Linacre College, and individuals re fundraising, donations by the EPA Cephalosporin Fund and other matters. This material was foundin oneoriginalfile. 2 folders. E.P. Abraham NCUACS103/2/02 31 SECTION C RESEARCH AND DEVELOPMENT C.1-C.1114 This section documents a variety of research by Abraham andhis colleaguesat the Sir William Dunn Schoolof Pathology and by a numberof other organisations. The greater part of the material relates to the work on Cephalosporin C and related compounds and the development of marketable cephalosporin antibiotics, though research on penicillin (from 1940), bacilysin and other antibioticsis also covered. Papers relating to the cephalosporins is dispersed through most of the sub-sections listed below. The correspondence covering the stages of the collaborative research from the late 1940s to the introduction of the first cephalosporin drug in 1964 is chiefly found in the sub-sections ‘Medical Research Council’, ‘National Research Development Corporation’ and ‘Other Organisations’. C.1-C.206 EARLY RESEARCH AND RESEARCHONPENICILLIN C.207-286 LABORATORY NOTEBOOKS AND PAPERS C.287-C.357 MEDICAL RESEARCH COUNCIL C.358-C.605 NATIONAL RESEARCH DEVELOPMENT CORPORATION (NRDC) (BRITISH TECHNOLOGY GROUP (BTG)) C.606-C.963 OTHER ORGANISATIONS C.964-C.989 SCIENTIFIC CORRESPONDENCE C.990-C.1016 BACILYSIN RESEARCH C.1017-C.1037 LEGAL CASES C.1038-C.1067 ‘CEPHALOSPORIN C HISTORY’ C.1068-C.1114. MISCELLANEOUS PAPERS E.P. Abraham NCUACS103/2/02 32 Research and development C.1-C.206 EARLY RESEARCH AND RESEARCH ON PENICILLIN 1935-ca 1949 C.1-C.4 DysonPerrins Laboratory notebooks C.5 Rockefeller Travelling Fellowship (Stockholm) C.6-C.14 Early William Dunn School of Pathology notebooks C.15-C.206 Penicillin reports C.1-C.4 DysonPerrins Laboratory notebooks 1935-1938 Abraham worked at the Laboratory from 1936-1938, researching on peptides. Hardback notebooks containing manuscript notes by Abraham mostly relating to experiments, including tables and graphs of experimental results. All are inscribed ‘Dyson Perrins Laboratory’ except C.4 which probably belongsin this set, being of very similar physical appearance to C.1-C.3 and dated 1938. Recordsof particular experiments are often dated. Mostly re experiments involving Undecylenic acid, October 1935-ca June 1936. From front notes on various experiments; from back notes on experiments involving lysozyme. Undated. Abstracts from papers on various experiments with references at end, undated. General notes on various compoundsand reactions. Inscribed ‘1938’ inside front cover. C.1 C.2 C.3 C.4 E.P. Abraham NCUACS 103/2/02 33 Research and development C.5 Rockefeller Foundation Travelling Fellowship (Stockholm) 1938-ca 1949 Notebook inscribed inside front cover ‘Biokemiska Institutet...Stockholm’ (crossed out) and‘Sir William Dunn Schoolof Pathology’. The notes cover Abraham’s period Foundationtravelling fellow, 1938, 1939. in Stockholm as a Rockefeller Re experiments involving various enzymes, October 1938-August 1939. Paginated 1-150 (pages 1-147 used), with further notes at back. See also A.18. C.6-C.14 Early Sir William Dunn School of Pathology notebooks 1940-ca 1949 C.6 C.7 C.8 The notebooks vary considerably in physical appearance. Some include loose pagesof notes. Re experiments involving various substances, including enzymes and intestinal mucosa, and early experiments on penicillin (June-ca October 1940). January-October1940. Re various experiments on penicillin and its purification, November 1940-ca August 1942. Re various experiments on penicillin and related compounds (including penicillanimine), and experiments unrelated to penicillin, August 1942-ca November1947. This notebook appearsto be a continuation of C.7. C.9 Notebookwith heading ‘Penicillin Analyses’ onfirst page. brief notes relating From front: results on various compounds, May 1941-ca 1943; from back: similar notes on compounds, including cephalosporins, ca October 1949. to experimental E.P. Abraham NCUACS 103/2/02 C.10 Research and development 34 From front: notes on ‘Penicillin Purifications’, September 1941-ca February 1943 (somelater notes may notrelate to the heading); from back: notes re experiments on penicillin and related compounds, ca November 1941-ca July 1942; notes following heading ‘Penicillin: Mode of Action etc... 10.1.45’, January-April April- September1945; 1 further page of notes, January [71946]. ‘Proactinomycin’, heading 1945; notes following Notebook inscribed ‘Spiraca and Arctium’ on cover. hand, partly in another's hand. Partly in Abraham’s Notes on various experiments, July 1944-ca May 1945. C.12 Notebook inscribed ‘Abstracts’ inside cover. Notes on various compounds,ca 1945-ca 1949. C.13 General notes headed ‘Use of moulds in primitive medicine’, ca 1945-ca 1949. Included at backis a letter to Abraham re arrangements for his lecture on ‘Penicillin Chemistry’, Oslo, 9 April 1946. C.14 Notebook (cover missing) entitled ‘Penicillin Abstracts’. Notes on penicillin and on various other compounds and processes, ca 1948-ca 1950. C.15-C.206 Penicillin reports 1944-1946 Copies of reports (many are entitled ‘Progress Reports’) by various organisations in the UK and the USAdetailing the progress of chemical research on penicillin, with related papers and correspondence. There are a number of different series of reports; these sequences have been maintained or reconstructed whereidentification was possible. E.P. Abraham NCUACS 103/2/02 35 Research and development C.15-C.146 Committee for Penicillin Synthesis (CPS) reports, 1944-1946. Copies of typescript reports by various organisations, including the Sir William Dunn School of Pathology, ICI Ltd (Dyestuffs Division), Imperial College London, Merck & Co.Inc., Glaxo and the Squibb Institute of Medical Research. The reports are in a numbered sequence, ‘CPS 1-698’. A few are missing. Mostly progress reports and studies on particular processes involving penicillin and related compounds. A few reports contain manuscript annotations by Abraham. C.15, C.16 3 copies of the index to the series. 2 copies include manuscript annotations. 2 folders. C.17-C.26 Reports: nos CPS 1-106, January-June 1944 (a few dated 1943). 10 folders. C.27-C.37 Reports: nos CPS 107-207, January-June 1944 (a few dated 1943). 11 folders. C.38-C.56 Reports: nos CPS 208-299, March-October 1944 (mostly June-October). 19 folders. C.57-C.77 Reports: nos CPS 300-399, September 1944-February 1945. 21 folders. C.78-C.99 Reports: nos CPS 400-502, December 1944-May 1945 (with a few possibly earlier). 22 folders. C.100-C.121 Reports: nos CPS 503-599, April-August 1945 (with a few earlier). 22 folders. E.P. Abraham NCUACS 103/2/02 36 Research and development C.122-C.146 Reports nos CPS 600-698, July 1945-May 1946. 25 folders. C.147 Papers relating to meetings of the Committee for Penicillin Research, November 1944-September 1945. With a few other papers found with this material. C.148-C.168 Copies of reports by various organisations, including Glaxo Laboratories Ltd, Boots Pure Drug Co. Ltd and Imperial College of Science and Technology, 1941-1945. Many reports are inscribed ‘Professor Sir R[obert]. Robinson’. C.148-C.161 Incomplete series of reports numbered PEN.1 - PEN.150, January 1941-July 1945. The series was found unevenly distributed in 2 parts, one group of reports being tied together with a label, ‘Dr Abraham’. The larger group is referred to below as the ‘main part of the series’. Some later reports are stamped ‘property of the Therapeutic Research Corporation of Great Britain Ltd’. C.148-C.157 Main part of the series. 10 folders. C.158-C.161 Reports labelled ‘Dr Abraham’. 4 folders. C.162-C.168 Incomplete series of reports numbered PEN.X. 1 March 1945. - PEN.X. 54, July 1942- Some reports Corporation of Great Britain’. C.148-C.161, the reports being very similar in structure and content. Therapeutic Research This series appears to be related to that in are stamped ‘property of the 7 folders. E.P. Abraham NCUACS 103/2/02 37 Research and development C.169-C.177 Incomplete series of reports (copies), numbered PEN.C. 3 - PEN.C. 107, May 1943-September 1945. Reports are mostly by official bodies, such as the National Research Council and include conference reports. See C.202-C.206 for further reports from this series. 9 folders. C.178-C.183 Copies of Control... Technical Papers Received from USA’, 1942-1945. ‘Ministry entitled reports of Supply, Penicillin Production The material includes various different series of reports which were found in a mostly disarranged state. Sequences have been re-constructed where identification was possible. Included at C.179 is a carbon copy of a typescript by Ernst Chain entitled ‘Brief account of the circumstances which led to the discovery of the chemotherapeutic properties of penicillin at the Sir William Dunn School of Pathology, Oxford’. 6 folders. C.184, C.185 Typescript papers, mostly minutes etc, re the business of the General Penicillin Committee, 1942-1944. With a few related reports found with this material. 2 folders. C.186 Correspondence between Sir Robert Robinson and the Therapeutic Research Corporation of Great Britain, October 1942-December 1943; papers re meetings on penicillin research, 1942-1943. Contents ofa file. C.186-C.201 Miscellaneous reports and other papers, with brief correspondence, 1942- 1945. The material is mostly typescript, with manuscript papers in an unidentified hand. At C.197is a letter (1943) from Sir Robert Robinson to Ernst Chain. There was no indication of any original organisation of these papers and no attempt at re-arrangement has been made. 16 folders. E.P. Abraham NCUACS 103/2/02 C.202-C.206 Research and development Contents University’. Copies of typescript reports, 1942-1944. ‘Penicillin inscribed of a file History..Pen 38 Reports..Oxford Most of the reports are from the ‘PEN.C’ series (see C.169-C.177) and appear to fill some gaps in the numbered sequence. Included at C.205 is brief correspondence between Sir Robert Robinson and Sir Edward Mellanby, 1943. 5 folders. C.207-C.286 LABORATORY NOTEBOOKS AND PAPERS 1946-1983, n.d. Binders and notebooks containing manuscript notes etc by Abraham and his research assistants at the Sir William Dunn School of Pathology. The material principally documents experiments relating to the development of the cephalosporins and other antibiotics and includes tables of results, graphs, and photographs. The notes are chiefly by research assistants, though many of the binders and notebooks contain notes in more than one hand. Arranged chronologically, though material has been kept together where identified as the work, or chiefly the work, of a particular individual. ‘Cephalosporin’ is abbreviated to ‘Ceph’ on the dividers found in the binders. C.207 Notebook, January 1946-July 1948. Notes in an unidentified hand. Mostly re experiments involving B. Subtilis and ayfivin; a few other notes from back re experiments on an antibiotic produced by Staphaur[?eus]. Paginated 1-185. C.208 Notebook, July-December 1948. Notes in same hand as C.207. Mostly re experiments involving ayfivin, continued from C.207; a few other notes from back; 1 loose page of notesat front dated June 1946. Paginated 186-230, of which 186-220 have been used. C.209 Large binder, December 1948-November 1953. Notes mostly in Abraham's hand; the remainder in an unidentified hand. Separated into sections by dividers labelled as follows: ‘Alvein’ (one page dated February 1949); ‘Bacilysin’ ([ca April]-May 1949); ‘Ayfivin’ (December = 1948-November 1953); ‘Pu[?ml]ulin’ (February 1951); E.P. Abraham NCUACS 103/2/02 39 Research and development ‘Ageritin’ (December 1952); ‘Nisin’ (June 1950-January 1952); ‘Micrococcin’ (October [?1951]-January 1952); ‘Techniques’ (pages dated September 1949, February-March 1950). C.210 Large binder, June 1949-February 1957. and partly in an unidentified hand. Notes partly in Abraham’s hand Separated into sections by dividers labelled as follows: ‘Cephalosporin’ (June-October 1949); ‘Cephalosporin N’ (November 1949-June 1954); ‘Methionine C.14’ (June-August 1954); ‘Synnematin B’ (October 1954); ‘Bacitracin’ (1955, 1956); ‘Ceph N / C14’ (September 1955); ‘Ceph P’ (December 1949-1952, 1957); ‘Nonin’ (February 1957). C.211 Notebook inscribed ‘Margaret Ann Keren Pill’, June 1949-March 1950. Re experiments on various compounds including ayfavin, penicillin and cephalosporins, with index and further notes from back. Paginated 1-159. C.212 Notebook inscribed ‘Ann Pill’, 1950-1951. Mostly re experiments on Cephalosporin N, with index from opposite end. Paginated 1-156. 29, with a few unpaginated pages. Included at the front is a loose set of notes paginated 1- C.212A Notebook in the hand of Ann Pill, undated. Headed ‘Methods and preparations’ on first page. Brief notes, probably for reference purposes. C.213 Large binder, 1951-1962. Notes mostly in Abraham's hand; the remainder in an unidentified hand. Separated into sections by dividers labelled as follows: ‘Ceph C’ (July 1954- February 1961); ‘Desacetyl Ceph C’ (February 1960-March 1961); ‘Ceph C,’ (January 1958-July 1960); ‘[''*C] Ceph C Acetate’ (June 1959-October 1961); ‘Rydon Smith Compfound] (Cephalosporidine)’ (May 1961-March 1962); ‘Penicillinase on C, Ca & Cc’ (January 1958); ‘Penicillinase’ (January 1960-ca February 1962); ‘Ceph C Nuchar Expts’ (January-February 1958); ‘Ca pyridine production’ (January 1958-March 1960); ‘Ca Nicotinamide’ (February-June 1958); ‘Ca Sulphapyridine Sulphathiazole’ (June-July 1958); ‘C, Glyoxaline’ (December 1961); ‘Ceph C conc HCl’ (June 1958-December Psst 1959): E.P. Abraham NCUACS 103/2/02 40 Research and development ‘Thiazole ‘Mixed crystalline acid from Ceph C spots 1+2+3’ (October-November 1958); ‘Separated cryst. acids 1, 2 & 3’ (November 1958-November 1961); ‘Ceph C performic oxidation product’ (November 1958-March 1959); ‘Benzoyl Ceph C’ (March 1959); 1959); ‘Ceph C Nucleus’ (July-September 1959); ‘Secretin’ (October 1955-October 1957); ‘Pancreozymin’ (March-April 1959); ‘Ceph C structural considerations’ (March-April 1962); ‘Polyacetylene Dr [?Landor]’ (February-March 1962); Unlabelled (possibly a continuation of ‘Techniques’), includes 2 graphs dated January 1951, and 1962. (October 1958-April ‘Techniques’ acylation 1959); dated etc’ (one page May C.214 Paperback notebook inscribed ‘M. Read’ on cover, ca May-ca October 1953. Contains experimental data (details of the nature of experiments are not given) and general notes on chemistry and human anatomy. C.215 Notebook inscribed ‘M.L. Read’ on cover, July 1954-September 1955. Re experiments synnematin and Cephalosporins C and N. involving various compounds including penicillinase, C.216 Notebook inscribed ‘M.L. Read’ on cover, October 1955-October 1956. Re experiments involving various compounds including penicillinase and Cephalosporins C and N. C.217 Notebook inscribed ‘Mary L. Read’ on cover, October 1956-January 1958. experiments Re Cephalosporin C, bacitracin and penicillinase. involving various compounds including secretin, C.218 Notebook inscribed ‘Mary L. Read’ on cover, January 1958-December 1958. Mostly re experiments involving Cephalosporin C. C.219 Notebookin the hand of Mary L. Read, December 1958-March 1960. Mostly re experiments involving Cephalosporin C. C.220 Notebook inscribed ‘M. Loveridge’ inside cover (in the same hand as C.214- C.219), March 1960-November 1961. Mostly re experiments involving Cephalosporin C. E.P. Abraham NCUACS 103/2/02 A Research and development C.221 Notebook inscribed ‘M. Loveridge’ inside cover (in the same hand as C.214- C.220), November 1961-February 1962. Mostly re Cephalosporins C and G. C.222 Large binder, June 1955-February 1958. Notes in unidentified hand. Mostly re experiments involving penicillin and Cephalosporins C and N. C.223 Large binder labelled ‘Ceph C D[ ? Js 1961’, October 1960-July 1962. Notes in unidentified hand. At beginning: notes re experiments involving various compounds including a-aminoadipic acid and Cephalosporin C, October 1960-January 1961. Then separated into sections by dividers labelled as follows: ‘Run 8 fo - valine (January 1961-March 1962); ‘Run 13 "a — acetate 24hr(February- April 1961); ‘Run 16 [''* C] acetate 24 hrs’ (May-July 1961); 1’ C] - acetate 48 hrs’ (June 1961); ‘Compound P [?] Run 17 48 hr Ac’ (October, November 1961); ‘/'4C] - a Aad Run 18’ (July 1961); [°'*C] - cystine Run 19 (September 1961-May 1962); ’“C] a Aad R.24’ (November 1961-July 1962); ‘Run 28 o - oxo - glutarate 5 ac (April-December 1961); ‘Media and washed mycelium expts’ (October 1961-February 1962); ‘Synthesis of A a - aminoadipic acid’ (March-May 1961); ‘Synthetic [?wash] Cephalosporidine etc’ (March-July 1962); ‘Radioactivity standards and backgrounds’ (April 1961-February 1962). C.224 Notebook inscribed M.L.R. Sharp, September 1961-April 1962. Re experiments on various compounds including acetic acid, carboxylic acids and Cephalosporin C. C.225 Large binder inscribed ‘M.L.R. Sharp’ on spine, March 1962-December 1963. Separated into sections by dividers labelled as follows: ‘D, L Valine uptake’ (December 1963); ‘Benzyl penicillin prepn’ (November, December 1963); ‘Est. of cpds [?compounds] 1&2 from ceph C’ (March-May 1962); ‘a - Aad — (April-May 1962); ‘Penicillaminic acid’ (May 1962); ‘Lysine . Arginine’ (May- June 1962); ‘Cephalosporidine synthesis spectra etc’ (April-September 1962); ‘Imidazole 1-acetic acid spectra’ (May-June 1962, with a few pages dated October 1960); ‘Dimethoxybenzoyl 7ACA’ (September 1960, June 1962); ‘DMBz 7ACA’ (June-October 1962); ‘7ACA’ (July 1962); ‘Hydrolysed mycelium saccharopine’ (September 1962); ‘p-nitro-phenolchloracetate’ (October 1962-November 1963); ‘Acetyl methionine’ (December 1962); ‘Hog acylase |’ (December 1962); ‘N-chloracetic DL-a-NH[?]’ (December 1962-Dec 1963, with one page dated April 1960); ‘y-OH valine, y-OH valine lactone’ (April 1963); Isa (July-September experiments’ 1962); ‘L — E.P. Abraham NCUACS 103/2/02 42 Research and development ‘Rotation of a.a. (a—Aad) ex fermentation + “peptides” [?] (glutathione, saccharopine)’ (April-July 1963); ‘Uptake of D & L a Aad by washed[?susp]’ (July-October 1963); ‘Ceph N degreda” products (maps)’ (February-April 1963); ‘Ceph C est. by elution’ (February, March 1963); ‘Disintegrated cells homogeniser’ (October, November 1963); ‘N-ethyl [?morpheline] [?] buffer’ (January 1963); ‘Ceph C stand[ard]’ (November 1962); ‘Add” of C"* cystine to anaerobic resuspension’ (November 1963); ‘C * NaOAc’ (October, November 1960, October 1962); ‘Instruments Hilger’ (May-October 1962); ‘Instruments N. Chicago counter’ (May 1962-June 1963); ‘X-press Expt. 2 [?] (Miriam)’ (November 1963); ‘Background IDL counter’ (April, May 1962); ‘M.Wts [Molecular Weights]’ (undated). C.226 Notebook in unidentified hand, May-August1963. Mostly re ‘Pyo Enzyme Experiment’ and ‘X-Press Experiment’. C.227 Large binder inscribed ‘JMT’ on spine, October 1963-August 1965. (May, June ‘Glaxo extract 1965); Separated into sections by dividers labelled as follows: ‘Uptake after sonication’ (November, December 1964); ‘Cell-free system. sonicator’ (January 1964); ‘Demaine’s and Aida’s buffers’ (January 1964-August 1965); ‘p-Fluorophenylalanine’ - SH measurement’ (May 1965); ‘Measurement of SH DTNB’ (March-May 1965); ‘N-chloracetate a - Aad acid’ (September-December 1964); ‘A expts sonication’ (October 1964-January 1965); ‘Model expts a - ketoadiplic]’ (January 1965); ‘Pimafucin’ (November, Decmber 1964); ‘Assays Ceph C and Ceph N’ (September 1964); ‘X-Press’ (July-October 1964); ‘Isolation D- valine from Cephalosporium’ (May 1964); ‘X-Press 3 experiment’ (January 1964); ‘Cell-free system homogeniser’ (February 1964); ‘Disintegration of mycelium’ (homogeniser)’ (October, November 1963); ‘Nessler’s solution’ (June-September 1964); ‘Nessler’s model experiment’ (September 1964); ‘Conwayvessels’ (July 1964); ‘Optical configuration D and L Alanine D and L Tyrosine’ (April, May 1964); ‘a-Amino-adipic acid’ (June 1964); ‘70% ECOH extractions MSE homogeniser (February 1964); TTC Benzyl penicillin potassium salt’ (January 1964); ‘Bacilysin — chromatogram (Mrs Lomakina)’ (January 1964-March 1965); ‘Bacilysin’ (February-July 1964); ‘Dowex column alanine & tyrosine’ (June 1964); ‘Ceph C absorption measured (Hilger)’ (October 1963-July 1964); ‘Assay For Prof. Jones (D.P.)’ (October 1963); ‘Production curve of Ceph N & Ceph C’ (November 1963); ‘Nuclear Chicago plateau’ (November 1963); of Warburg manometers’ (April 1964); ‘Colony counts sonicator’ (January-April 1965). ‘Calibration C.228 Large binder inscribed ‘GFN Peptides’ and ‘Takano-san’ on cover and ‘G.F. Newton’ inside cover. The label ‘Paul’ appears on the spine. October 1964- December 1968. Separated into sections by dividers labelled as follows: ‘2pBWA 1’ (January 1967); ‘2bBWA 2’ (January 1967-November 1968); ‘PBG2/3[?] G/C5, G.10 col’ (July [?1967]); ‘PBG2/3 G10 GC3 G10 G/C4 G10’ (June, July 1967); be E.P. Abraham NCUACS 103/2/02 43 Research and development PYR’ ‘TCB+PB G25-70% ‘PBG2&3 Ac [?Els] G10’ (January-September 1967); ‘PB G1’ (January 1969); ‘PBG2’ (undated); ‘PBG3’ (undated); ‘PBG4’ (one page dated March 1968); ‘GCB+PB Separation of GSO3sH & Taurine on G10 — HOAc’ (March, April 1968); ‘TCB+PB 2oBWA[?]’ (April 1968); ‘TCB+PB2¢BWA POOL P3’ (May-August 1968); ‘POOL Ps 2bBWA 2’ (May 1968); ‘POOL P; 26BWA3’ (May-June 1968); ‘Analysis of pools from 2bBWA col[?]’ (June 1968); ‘Po middle ex. 2oBWA 2 [?] 2bBWA 4’ (June 1968); ‘TCB+PB Pool “GSOsH” 2pBWA 5’ (October 1964-December 1968). (February-April 1968); C.229-C.232 Loose pages of notes, originally from a binder, 1964-1965. Contents of file inscribed ‘Joan Roscoe’. ‘A-H’. labelled Separated into sections by dividers Included among numerous topics and experiments are the following: Section A: Contents [index to sections A-G only]; B: ‘Medium of H.J.O. Rogers, record of B. subtilis A14 culture’ (January-June 1965); C: ‘Test run on Rogers’ medium, investigation of inocula’ (September, October 1964); D: ‘Bacilysin production [etc]’ (October-December 1964); E: ‘Expt. To see if [?chloramphenicol] can be extracted [etc]’) (December 1964-January 1965); ‘Treatment of bacilysin sample & freeze-drying, preparation of large quantities of acetone extract’ (February-May 1965); G: ‘Expt. To follow glucose utilization & bacilysin pro[?dn], further attempts to establish the identity of the radioactive & postulated bacilysin spot’ (April-July 1965); ‘Shikimic acid’ (July, August 1965); H: ‘Comparison of zones given by Cephalosporin C and bacilysin 208’ (August 1965). F: Paginated 1-275. 4 folders. C.233 Notebook inscribed ‘LDS [Leon D. Sabath] Rabbit Expts’ on cover, February 1965-January 1966. Rethe study of penicillin antibodies in rabbits. C.234 Large binder, January 1965-April 1972, with one page dated 1964. 2 pagesin the index (see below) headed ‘Bronwen Loder’. Separated into sections by dividers labelled as follows: ‘Index’; ‘GA, GC, CV’ (January 1968-July 1969); ‘L-C-D-V’ (July 1969-September 1969); ‘L-C-L-Y’ (June-September 1969); ‘C-L-V Cu precipitate’ (July-September 1969); ‘Trityl cpds [?compounds]’ cysteine’ (February-December 1965, February 1969); ‘Hydrazide - AC’ (March- December 1965); ‘Mycelium expts AC-ACV’ (May 1965-January 1966); ‘Mycelium expts GC’ (April 1968-November 1969); ‘HS-‘ (May 1965-January 1966, November 1968-February 1970); ‘Sonication expts’ (November 1965); /... ‘Enzymes’ (June 1965, March-June 1968); (January-March ‘S-benzyl 1965); E.P. Abraham NCUACS 103/2/02 44 Research and development ‘Actinonin’ (January-November 1965, one page dated October 1964); ‘Actinonin M. Jago’ (June 1962); ‘Misc’ (September 1965, February 1969- June 1970); ‘Atta Rhozities gargylophera’ (January 1971-April 1972) ; ‘DMB’ (October 1970-September 1971). Loose material at front. C.235 Large binderlabelled ‘P.B.[Bronwen] Loder’ on spine, 1968-1972. 1972); ‘Photoplasts’ (February-May ‘Hydroxamic acids’ Separated into sections by dividers labelled as follows: Unlabelled pagesat beginning re experiments involving Park nucleotides, Cephalosporin N and other compounds (October 1969-June 1971); ‘Ceph N’ (September 1969- May 1970); ‘Methods’ (January 1968-September 1969, November 1971); ‘ACV’ (November 1971-July 1972); ‘““C-D-Val + a KIV’ (November 1971); ‘Resolution of a Aad‘ (June- Glu.Ala Cy SO3H.Gly (January 1969-February October 1970); ‘Glu.Gly 1972); mercaptides’ (September 1969-July 1972); ‘CFS Ceph. Sp’ (May 1970-March 1972); ‘CFS Penicillium’ (May 1969-June 1972); ‘Ceph sp. Sonicates’ (May 1970-July 1970); ‘P4 Complex’ (June 1970-January 1971); ‘7-ACA’ (February 1968- July 1972, one page dated November 1965); ‘PS and slow spot’ (November 1970-February 1971); ‘Glaxo copper precipitate’ (June 1969-July 1970); ‘Cuprous mercaptides’ (August-December 1970); ‘Esters’ (March 1969- August 1970); ‘Model mixture a[?ml]ino acids’ (March, April 1969); ‘ORD’ (March-September 1969); ‘Amino acid markers’ (September-November 1969); ‘Phenylacetyl Ceph C & penicillin] N’ (March-June 1970); ‘Ceph October uptake expts’ (October 1969-December 1971). (May-December 1971); ‘Cuprous C.236 Large binder labelled ‘T.J.B.’ on spine, 1965-1982. hand. Notes in Abraham's Separated into sections by dividers labelled as follows: ‘P. chrysogenum SC 6140’; ‘Ceph C standards’ (November 1975); ‘Steptomyces’ (January 1972, July 1974-October 1975); ‘B.subtilis 6633 Rapid assay’ (March 1972); ‘Pen icillinjase Pseudomonas’ (October 1972-October 1974); ‘Pen’[icillinjase B. cereus 569 H’ (July 1968, March-June 1974); ‘D-amino acid oxidase - Aspergillas’ (February 1968-February 1959, July 1973); ‘Q176 / C21 P. chrysogenum’ (January 1968-May 1973, June 1979); penicillin acylase’ (February-March 1974, January 1982); ‘Ceph CW 19’ (July 1973- October 1974); ‘Acremonium’ (January-February 1973); ‘Cephalosporium C91’ (November 1965-November 1971). ‘E.coli Paginatedin part from back 1-128. C.237 Large binder labelled ‘J. Walker purification expts’ on spine. 1966-1969. Bacilysin. Production expts. Early Separated into sections by dividers labelled as follows: ‘Protease’ (February, March 1967); ‘NMR’ (September 1968-March 1969); ‘Bacilysin hydrolysis’ (October, 1968); ‘Crystallization’ (September, October 1968); November 1968); (May-November spectra’ ‘Mass /... E.P. Abraham NCUACS 103/2/02 45 Research and development ‘Terreic acid’ (October 1968); ‘I.R. spectrum bacilysin’ (September 1968); ‘Bacilysin detection’ (March 1969); ‘O.R.D.’ [no notes]; ‘LAP’ (February 1969); ‘Action on fungi & yeasts’ (June 1966-April 1969); ‘Bioautography bacilysin lactone [?]’ (May 1969); ‘cbz bacilysin’ (March, April 1969); ‘Effect of bacilysin on B. subtilis’ (June 1969); ‘Production of bacilysin by Warburg’ (March 1966); ‘N-acetylglucosamine bacillin’ (January 1966-January 1969); ‘Phenylacetyl bacilysin’ (May 1969); ‘B. subtilis mutants’ (December 1966- July 1969); ‘B. subtilis extracellular supernatant’ (June, July 1969); ‘A14 intracellular’ N-acetylglucosamine’ (December 1968-June 1969); ‘Agar AB’ (December 1966-April 1969). (August, September 1969); ‘Bacillin C.238 Large binder labelled ‘J.E. Walker purificat". Compounds P1, P2, P3. Tyrosine. CrCl, red”. 1968, 1969. Bacilysin. Sephadex A25. Large scale Separated into topics by dividers labelled as follows: ‘Purification (cont)’ (January-December 1968); ‘P1, P2, P3’ (September 1968-October 1969); ‘p- nitrophenol TFA’ (June 1968); ‘t-BOC Ala.Ala-‘ (November 1968); ‘CrCl, reduction’ (September, October 1968). C.239, C.240 ‘Amino acid analyses — bacilysin J.E. Walker’, contents of a file so inscribed. Chromatogram graphs from experiments by J.E. Walker, with a few accompanying data sheets, 1968, 1969. 2 folders. C.241 Large binder labelled ‘Sylvia Main Book |’ on spine, 1966-1968, with a few notes dated 1965. imine’ styrene resin’ (January, February 1968); Separated into sections by dividers labelled as follows: ‘Fungal luciferin’ (January-February 1966); ‘Mycelium expts’ (January 1966-May 1968); ‘Glaxo compounds’ (January 1966-February 1967); ‘Glaxo ceparin [appears as ‘ceporin’ in the notes]’ (May-July 1967); ‘7ACA’ (July 1967); ‘7ACA tosylate’ (February, March 1968); ‘ACV and GSH’ (January 1966-May 1967); ‘Ethylene (February 1966- November 1967); ‘N- phenylmaleimide [?]' (July-December 1966); ‘Whatman ion exchange cellulose Amino Ethyl AE11’ (August 1966); ‘Anion exchangecellulose cellex PAB’ (September 1966); ‘B-Lactamase’ (May 1966-April 1968); ‘Actinomycin D’ (June 1966); ‘Spectra of tyrosine & tryptophan’ (July 1966); ‘Desacetoxy cephaloglycin & cephaloglycin’ (January, February 1967); ‘Miscellaneous’ (March 1967-December 1968, with a few pages December 1965); ‘Safety’ (undated). ‘Polyamino ‘Assays’ (June-July 1966); Loose notesat front. E.P. Abraham NCUACS 103/2/02 46 Research and development C.242 Large binder labelled ‘Sylvia Main BookII’ on spine, 1967, 1968. Separated into sections by dividers labelled as follows: ‘Index’; ‘7ACA’ (June 1967-April 1968); ‘Ceph C + ENH, cap: (February-May 1967); ‘Ceph C + cysteine’ (April, May 1967); ‘Ceph C + a & B- ala’ (July-October 1967); ‘Ceph C + Lys[sine] & polylys’ (July-September 1967); ‘Ceph C + NH3’ (July- October 1967); ‘Reactions with B-lactamase’ (February-October 1967); ‘3- methyl Ceph C’ (August, September 1967); ‘Deacetyl Ceph C’ (October 1967); ‘Ceph C + heavy metals’ (October, November 1967); ‘Ceph C + NaBH,’ (September-November 1967); ‘Misc’ (February-November 1967). C.243-C.250 Loose pages of notes, originally from a binder, 1968-1970. Contents of a box labelled ‘Jeremy and Anne’. Separated into sections by dividers labelled as follows: ‘Antibodies to B- lactamase’ (October 1968-[?November] 1970); Antibodies to C & @’ (October 1968-July 1969); ‘Antibodies to dc + [?dyl] c’ (June-September 1969); ‘> assay’ (December 1968-March 1970); ‘Antibodies to rabbit RBC’ (November 1968-April 1970); ‘Animal log’ (May-September 1969); ‘Reaction pen G etc ERBC BGG’ (November 1968-May 1970); ‘B-lactam conjugates’ (October 1968-June 1970); ‘Haemagglutinate of pools v.s. various cells’ (October 1969-June 1970); ‘Hapten inhibition’ (September 1969-April 1970); ‘Purification of antibodies’ (August-October 1969); ‘Ouchterlony’ (September, October 1969); ‘Quant. ppts’ (September-December 1969); ‘7ACA A’ [ ? ] A” (October 1969-May 1970). 8 folders. C.251-C.268 Notes etc (1 original binder, the remainder loose pages from binders), 1978- 1983. Numerous references indicate that this material was the work of Dr J.S. Jayatilake. The notesareall in the same hand. The loose notes in C.251-C.267 were found together. C.251-C.254 Loose notes, October 1978-November 1980. Contents of a file inscribed ‘Synthesis of ISON and conversion of ISON [arrow] Penlicillin] N by an [?epimerase]’. Paginated 1-78. 4 folders. E.P. Abraham NCUACS 103/2/02 47 Research and development C.255-C.264 Loose notes, 1979, 1980. These notes appear to be a continuation of the material in C.251-C.254. 1980); ‘Penicillinic acid Separated into sections by dividers labelled as follows: Labelled 6-APA’ (October, November 1979); sulfone (hot and cold)’ (January-[ca June] 1979); ‘(LLD) ACV’ (March 1979-May 1980); ‘(LLD) ABV’ ‘(LLD) GCV’ (ca April (September 1979); ‘(LLD) CCV’ (September 1979-September 1980); ‘(LLD) ACB’ (March-December 1980); ‘(LD) — [?Decanboxy] ACV (UCV)’ (September, October 1980); ‘(LD) Adipyl CV’ (November 1980); ‘Adipyl-L-cystein dipept.’ (January 1981); ‘(LD) CV- dipeptide’ (April [?1980)). ‘(LLD) ASV’ (March-September 1980); 1980); ‘(DLD) ACV’ (July, August Paginated 78-161 (some material is unpaginated). 10 folders. C.265-C.267 Loose notes, October 1982-February 1983. ‘Synthesis of “cold” & “hot” ACG Attempted labelling expts’. Contents of a file inscribed In the same hand as C.251-C.264. 3 folders. C.268 Large binder labelled ‘GSJ 4 experiments’. 1981, 1982. Penicillin chrysogenum. Prep" of extract & Separated into sections by dividers labelled as follows: ‘P. Chrysogenum ext. G25/S/N & G25[?]N’ (April 1981); ‘P. Chry: G25 NS/N CV dipep Activ[ity] / Inhi[bition]’ (March, April 1981); ‘P. Chryso: Assay of ASO-50, 50- 65, 65-80, 80+’ (April, May 1981); ‘P. Chrys: protein fraction DEAE seph[?] A50’ (May 1981); ‘P. Chrysogenum Dyno mill Il / DEAE — [?sol]’ (May 1981); ‘R.1221 P/C harvest[?]’ (May 1981); ‘Gel-electro phoresis’ ([?May or June 1981] ); ‘P/C R1221/1 Dyno mill large scale’ (June 1981); ‘P. Chrysogenum Dyno mill small scale’ (June 1981); ‘P/C Dyno mill 0-80% DEAE-seph R1221/2’ (June 1981); ‘Dyno-mill R1221/3’ (June, July 1981); ‘Dyno-mill R1221/4’ (July 1981); ‘P/C R1221/2 DEAE/AS/0.5[?]0.2’ (July 1981); ‘G100 calibration’ (July 1981); ‘P/C R1221/5 DEAE/AS G100’ (July 1981); ‘ACV activity’ (July, August 1981); ‘ACV activity 1,28&3% ACV [?]’ (August 1981); ‘R1221/6 extract G100 / mol wt.’ (August 1981); ‘Effect of catalase triton x- 100 G100 extract’ (August 1981); ‘ACV [?dimer] / [?] P. Chrys & acrem.’ (August 1981); ‘Km ACV — IN [?lsopenicillin N] in P.C.’ (August 1981); ‘G100 column’ ‘Km — Deter[mination]’ (September 1981); ‘ACV [?dimer] activit / also with C. acremonium’ (September 1981); antibiotics production’ (September 1981); ‘Effect of co-factors’ (October 1981); ‘1. 2. DEAE in MOPS’ (October 1981); ‘Dyno mill Effect of a-ketoglu[tinate] R1225/1’ (October 1981); ‘Stability in various buffers’ (October 1981) ‘R1225/2 Extract prep'- ‘TRIS’ 7 & 8’ (December 1981); ‘Activity Bacilysin samples’ (December 1981); ‘R1225/3 dyno mill’ (December 1981); ‘R1225/4’ /... (December 1981); ‘R1225/5’ (January 1982); harvest time (September (September ‘R1223 / 1981); 1981); ‘P,; value’ E.P. Abraham NCUACS 103/2/02 48 Research and development ‘R1225/6’ (February 1982); ‘R1225/7’ (March 1982); ‘Prep — Gel expts’ (March 1982) ; ‘Harvest of Ps in “old” & “new” media Dyno mill extracts’ (April 1982); ‘Use of chromatofocussing phenylsepharase columns’ (April 1982); ‘P. in “old” — large scale Dyno mill’ (April 1982); ‘Chromatofocussing 2nd expt’ (May 1982); ‘Use of phenylsepharase at 35% AS conc” (May 1982); ‘1. Harvest of Ps in old media in fermentor 2. Pz / new / shakeflasks’ (May 1982); Ps (350g) — Dyno mill extract’ (May-July 1982). C.269-C.282 Loosenotes, originally from a binder, 1979. Separated into sections by dividers labelled as follows: Untitled notes at front (September 1979); ‘Dialysis in Fe etc [?1h]’ (September 1979); ‘Dialysis 68 [?1h]’ (August, September 1979); ‘Ph 66’ (August 1979); ‘Co-factors 64 65’ (August 1979); '50,000g 61’ (July 1979); ’20,000g 50,000g 60’ (July 1979); ‘+ - DTT 20,000g 59’ (June, July 1979); ‘GSJ — ACV 20,000g 58’ (June, July 1979); ‘diffr[erential] assay 55’ (June 1979); ‘ACV: time’ (April 1979); ‘ACV / PL conc” (February-May 1979); A[encircled C]V + ACV 76’ (October 1979); ‘A[encircled C]V’ (October 1979); ‘Alencircled C]V, ACV 75’ (October 1979); ‘ACV / CP’ (May 1979); JEB / ACV /°H’ °H/'“C ACV ex JEB’ (July- September 1979); isopen N’ (February-April 1979); ‘N purif ™” (June-July 1979); ‘1153 N — C [?]' (January-July 1979); ‘C91 / 5H qaad’ (February, March 1979); ‘dialysis DTT 1h asc 72’ (September 1979). 14 folders. C.283 Binder inscribed ‘Henry Chmara Amidotransfer’ on cover, 1979 (with a few notes dated 1978 near back). Topics covered include ‘Purification of amidotransferase from E-coli ESS 22- 31’ (October 1979); ‘Action of Bacilysin in vivo inhibition of amidotransferase’ (August 1979); ‘Purification of amidotransferase from C[?oryne]bacterium 168’ (July 1979); ‘Purification of amidotransferase from Sup. 105000g’ (May 1979); ‘Purification of amidotransferase from E-coli MRE 600’ (March 1979); ‘Purification of a new part of E. coli MRE 600 and some aspects of interaction with bacilysin and anticapsin’ (February 1979). Loose notes at back. C.284 Notebook inscribed syn[?e]thetase’, June 1982-November 1983. Pang ‘C.P. Analytical PAGE Isopenicillin N Title on first page is ‘Gel electrophoresis’. This topic appears to cover all the notes in the book. E.P. Abraham NCUACS 103/2/02 49 Research and development C.285 Notebook in Abraham’s hand. From front: notes re visits to universities and institutions in the USA and re various chemical processes. From back: notes on atomic physics, isotopes and various biochemical processes. References to published sources indicate a possible date ca 1948. C.286 Manuscript numerical data, possibly relating to experiments, n.d. Found loose in unmarkedfile. C.287-C.357 MEDICAL RESEARCH COUNCIL 1949-1987 In July 1949 the MRC’s Antibiotics Research Station at Clevedon began to produceculture fluids from the cephalosporium fungus for study by the Sir William Dunn School of Pathology. In early 1952 Abraham’s colleague Guy Newton wassent to Clevedon to help speed up the supply of Cephalosporin N. The improved supply enabled Abraham’s team to isolate almost pure CephalosporinN. in producing sufficient quantities of Cephalosporin C for the Dunn School’s requirements, Clevedon workers discovered a mutant strain of the fungus which gave significantly higher yields. 1957, following Glaxo’s difficulties In Abraham servedonthe Scientific Steering Committee to oversee the work of the Antibiotics Research Station, Clevedon. The majority of the papers relate to the work of the Antibiotics Research Station and its collaboration with the Sir William Dunn School of Pathology. See C.1042-C.1048 for further correspondencere the work at Clevedon. C.287-C.292 Correspondence between Abraham and C.W. Hale of the Antibiotics Research Station, re research on cephalosporin, October 1949-December 1952. Included are copies of typescript reports by scientists at the Antibiotics ResearchStation and the Sir William Dunn School of Pathology. 6 folders. E.P. Abraham NCUACS 103/2/02 50 Research and development C.293-C.308 Contents of a file inscribed ‘EPA corresp. Clevedon — Oxford —- NRDC’. Correspondence, mostly carbon copiesofletters from Abraham to B.K. Kelly and G.W. Hale at Clevedon; included also is correspondence between Abraham, the National Research Development Corporation and Glaxo Laboratories Ltd. 1949-1961. C.293-C.296 1949-1954. 4 folders. C.297-C.300 1955-1958. 4 folders. C.301-C.307 1959-1961. 7 folders. C.308 Letters by Guy Newton to Abraham, ca [March- May] 1952. C.309-C.317 Drafts of papers co-authored by Abraham, with related material. Publication details given where known. C.309 1p copy of typescript abstract of a paper entitled ‘Properties of some derivatives of cephalosporin C and heterocyclic tertiary bases’, by C.W. Hale, Abraham and G.G.F. Newton, Supplement to International Abstracts of Biological Sciences (IV International Congress of Biochemistry, Vienna, September 1958); letter from Hale, 1958. C.310 ‘The Influence of Methionine on the Biosynthesis of Cephalosporin N’, by C.W. Hale, Abraham and G.G.F. Newton. 18pp copy of typescript draft with manuscript revisions; 2 letters re the content and possible publication of the paper, December 1958. E.P. Abraham NCUACS 103/2/02 C.311 51 Research and development ‘The Cephalosporin C Nucleus (7-Aminocephalosporanic acid)’, by G.G.F. Newton and Abraham. Probably published under thistitle followed by the additional words ‘and some of its derivatives’, by Bronwen Loder, G.G.F. Newton and Abraham, in Biochemical Journal 79, 1961. 13pp copy of typescript, with draft figures etc, with thefirst of the abovetitles and authors. C.312 ‘Formation of the cephalosporin C nucleus (7-ACA) by enzymic hydrolysis of an N-acyl derivative of 7-ACA’ by G.G.F. Newton and Abraham. 5pp copy of typescript draft with manuscript revisions. C.313 Copies of typescript appendices, possibly to the papers in C.309 and C.310. 2pp copy entitled ‘Appendix 1. “Incorporation of 1-"C Acetate into Cephalosporin C”’, by C.W. Hale, G.A. Miller, Abraham and G.G.F. Newton (possibly part of the paper published under this title, with the name P.W. Trown added to the authors, in Biochemical Journal 84, 1962). 6pp copyentitled ‘Appendix 2. “Cephalosporin C;”’, by G.G.F. Newton and Abraham. 5pp copy, with manuscript revisions, entitled ‘ Appendix 3. “Cephalosporin Ca (pyridine)” ’, by Abraham, G.G.F. Newton and C.W. Hale. C.314 ‘The Separation of Cephalosporin N and Cephalosporin C’, by G.G.F. Newton and Abraham. 8pp copy of typescript draft with manuscript corrections. C.315, C.316 Copies Cephalosporin C, with manuscript revisions and annotations. typescripts detailing of 5 various experiments, mostly re Found with the draft in C.314; one typescript is inscribed ‘separation paper’. 2 folders. C.317 Typescript report by C.W. Hale, December 1956; data and photographic prints (Some mountedonto cards). Found with the material in C.314-C.316. E.P. Abraham NCUACS 103/2/02 82 SECTION D PUBLICATIONS D.1-D.288 D.1-D.270 DRAFTS D.271-D.288 EDITORIAL CORRESPONDENCE E.P. Abraham NCUACS 103/2/02 83 Publications D.1-D.275 DRAFTS 1956-1998, n.d. Arranged chronologically. Undated drafts are at D.253-D.270. D.1 ‘Some Chemical and Biological Properties of New Antibiotics of the Penicillin Group’, co-authored with G.G.F. Newton, Chemical Science and Industry USSR I, 1956. 40pp photocopy of a typescript, with manuscript corrections and additions; 1p manuscript notes by another. D.2-D.10 Articles and book reviews by Abraham for Endeavour, contentsofa file. D.2, D.3 ‘The Antibiotics in Microbiology’, Endeavour 18, October 1959. Correspondence re publication with corrected proofs ofarticle. 2 folders. D.4 D.5 D.6 D.7 Review: Recent Progress in Microbiology, edited by G. Tunevall, Oxford 1959. Correspondence re publication; 1p photocopy of typescript draft of review and cutting of printed version. Review: ‘Antibiotics in Medicine’, British Medical Bulletin 1960 16, No.1. Letter with 1p photocopy of typescript of review. Correspondence re publication of an article ‘New Penicillins, Cephalosporin C and Penicillinase’, with G.G.F. Newton, Endeavour 20, 1961. The Molecular Basis of Antibiotic Action, by E.F. Gale et a/, Chichester 1972. Letters re review request with 1p photocopyof printed version of review. E.P. Abraham NCUACS 103/2/02 84 Publications D.8 D.9 D.10 Review:Fifty Years of Antimicrobials: Past Perspectives and Future Trends, edited by P.A. Hunter et a/., The Society for General Microbiology, 1995. Correspondence re publication; 1p manuscript and 1p typescript drafts of review, with corrected version. Correspondence re unidentified article by Abraham re Cephalosporin C, February-December 1960; letter requesting review of a book, 1955. Correspondence with Endeavourre orders for binding cases, 1958-1968. ‘Antibiotics’, Enciclopedia Medica Italiana, 1959 or later. Correspondence re publication, 1959; 26pp copy of typescript draft (with bibliography) with manuscript corrections. ‘The Chemistry and Classification of Antibiotics’, with G.G.F. Newton, British Medical Bulletin 16, 1960. 20pp copy of typescript draft (with tables and references) with manuscript corrections and additions. ‘Derivatives of Cephalosporin C formed with certain Heterocyclic Tertiary Bases’, with C.W. Hale and G.G.F. Newton, Biochemical Journal 79, 1961. Letter re preparation, 1960; 15pp copy of typescript draft (with references etc) with manuscript corrections; 3 typescript pages of other drafts and figures, probably related to the article. ‘New Penicillins, Cephalosporin C and Penicillinase, with G.G.F. Newton, Endeavour 20, 1961. 17pp copy of typescript draft (with references and figures) with manuscript corrections and additions. D.15, D.16 ‘The Cephalosporins: history and scientific background’, Medical News 48, 1963. Correspondencere publication; 7pp copy of typescript draft, with manuscript revisions, etc and copy of revised version with figure. E.P. Abraham NCUACS 103/2/02 85 Publications D.16 Copyof published version of the article, with extensive manuscript revisions and copy of revised version with figure etc, n.d. ‘Production of a Cephalosporinase by Pseudomonas pyocyanea’, with M.Jago and A. Migliacci, Nature 199, 1963. 4pp copy of typescript proof with manuscript corrections; reprint; copy of typescript, with figures, describing experimental results, probably related to the article. with manuscript corrections; draft D.18-D.20 Reviewsfor Nature, contents ofa file. D.18 D.19 D.20 D.21 Joint review article by Abraham covering a number of publications on antimicrobial agents and chemotherapy (mostly published in 1963), including Proceedings of the Antimicrobial Agents and Chemotherapy — 1962. Second and Chemotherapy, Chicago,Illinois, October 31-Novermber 2 1962, American Society for Microbiology 1963. Antimicrobial Interscience Conference Agents on_ Correspondence re review requests; 8pp photocopy of review article; corrected proof. Antimicrobial Agents and Chemotherapy — 1963. Proceedings of the Third Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington DC, October 18-30 1963, American Society for Microbiology 1963. Correspondence re manuscript corrections and copy of later typescript draft; corrected proof. 3pp typescript publication; review draft of with Antimicrobial Agents and Chemotherapy — 1964. Proceedings of the Fourth Interscience Conference on Antimicrobial Agents and Chemotherapy, New York, October 26-28 1964, American Society for Microbiology, [?1965]. 4pp copy of typescript draft of review; proof; copy of typescript probably relating to one of the reviews in D.18-D.20. Obituary for Professor Donald Devereux Woods, British Medical Journal2, 1964. 2pp copyof typescript obituary and cutting from off-print. E.P. Abraham NCUACS 103/2/02 86 Publications D.22 ‘The Cephalosporin Story’, New Scientist 24, No. 217, 1964. 6pp copyof typescript draft, with manuscript corrections, and figures; letter re publication. D.23 ‘The Chemistry of New Antibiotics’, The American Journal of Medicine 39, 1965. 21pp copy of typescript draft (with references and figures) with manuscript corrections; letter re publication. D.24-D.26 ‘Enzymic Behaviour of the Cephalosporins’, with L.D. Sabath, Enzymologia 29 (memorial volume to Professor H. von Euler), 1965. D.24 D.25, D.26 D.27 D.28 Correspondence re an article which Abraham contributed to a 1963 volume dedicated to von Euler on the occasion of his 90th birthday (apparently later published in the Biochemical Journal), October-November 1962. Correspondence the Cephalosporins’, with 1p copy of typescript ‘summary’ of the article and copy of typescript of article for the 1963 volume (see D.24). 1965, 1966. publication ‘Enzymic re of Behaviour of 2 folders. ‘The Cephalosporins’, with G.G.F. Newton, Advances in Chemotherapy 2, 1965. Proof with publication. manuscript corrections and revisions; correspondence re See C.562, C.563 for a draft of this paper. Review for Nature (published in 1965): Advances in Drug Research, London 1964. Letters re publication; 2pp copy of typescript of review and proof. D.29, D.30 ‘Experiments relating to the Biosynthesis of Bacilysin’, with J. Roscoe, Biochemical Journal 99, 1966. E.P. Abraham NCUACS 103/2/02 87 D.29 D.30 D.31 D.32 Publications 21pp copy of typescript draft (with references and figures) with manuscript revisions. Later copy of typescript draft with manuscript corrections. Review for British Medical Journal: Biochemical Studies of Antimicrobial Drugs, Cambridge University Press 1966. Correspondence re publication and 2pp copy of typescript of review with manuscript corrections. ‘The Cephalosporin C Group’, Chemical Society Quarterly Reviews 21, No. 2, 1967. Proof with manuscript corrections. See C.567 for typescript [?draft] of paper. D.33-D.114 Articles and radio broadcasts by Abraham on Howard Florey arising from the latter's death in February 1968, with related material. D.33 D.34 D.35 Appreciation of Florey in obituary notice by various writers, The Lancet, 2 March 1968. Letter of thanks; 1p of typescript message of appreciation; off-print. Appreciation of Florey in obituary notice by various writers, British Medical Journal, 2 March 1968. 1p copy of typescript message of appreciation with manuscript corrections; photocopy ofoff-print; letter of thanks. Obituaries for Oxford Magazine, 31 May 1968, and [?Lincoln College Magazine]. Abraham’s obituary for [?Lincoln College Magazine] was a revised version of the one he wrote for Oxford Magazine. Correspondence re obituary for Oxford Magazine, with corrected proof and copy of re-print with manuscript revisions; 2 copies of typescript drafts (8pp and 9pp) of obituary for [?Lincoln College Magazine] with manuscript corrections. E.P. Abraham . NCUACS 103/2/02 88 Publications D.36 ‘Lord Florey’, Chemistry in Britain 4, No.9, May 1968. Letters typescript. re 3pp typescript draft with manuscript corrections; 2pp copy D.37 D.38 2pp manuscriptdraft, with revisions, of obituary; copy of typescript corrected version; off-print. Publication unknown. [71968]. 1p untitled typescript draft Abraham and another, [?1968]. Publication unknown. of obituary with manuscript corrections by D.39 Short account of Florey’s life, Sunday Times Magazine, 1969. Correspondence re publication, May 1969; 1p copy of typescript draft, with manuscript corrections, of short account of Florey’s life inscribed ‘Sunday Times April 1969’. D.40-D.89 ‘Howard Walter Florey, Baron Florey of Adelaide and Marston 1898-1968’, Biographical Memoirs of Fellows of the Royal Society 17, November 1971. In March 1968 Abraham was asked to write the Memoir for which he undertook a great deal of research into Florey’s life in Australia and at Oxford. Despite having to negotiate some sensitive issues, he produced an article considered by most to be authoritative and very interesting. D.40-D.57 Correspondence and papers re Abraham’s preparation of the memoir, 1968- 1971. Correspondents include individuals and organisations with access to documentary records, former colleagues of Florey and his family and acquaintances. D.40-D.47 1968, 1969. 8 folders. D.48-D.57 1970-October 1971. 10 folders. E.P. Abraham NCUACS 103/2/02 89 Publications D.58-D.64 Correspondencearising from publication of the memoir, mostly letters of thanks from fellow scientists in receipt of copies, with congratulations and comments, September 1971-1972, 1974. 7 folders. D.65 Copy of off-print of memoir. D.66-D.89 D.66-D.69 Correspondence and papers preparation of the memoir. used by Abraham as_ background for Correspondence between Florey and the Medical Research Council re grants and assistance provided by the latter for research on penicillin, 1939- 1946. 4 folders. D.70, D.71 Carbon copies of extracts of letters by Florey, Lady (Ethel) Florey and Norman Heatley to John F. Fulton and Lucia Fulton, 1940-1945. Paginated 1-66. Contents of file. 2 folders. D.72 Photocopies of letters by Florey to John F. Fulton, 1947-1954. Contents ofa file. D.73 D.74 D.75 Photocopies of correspondence relating to Florey’s fact-finding tour to Australia and New Zealand in 1944 to visit medical establishments and photocopyof his report of the tour, 1945. Letters to Abraham from Florey, with related material, 1953-1968. Miscellaneous correspondence of Florey, mostly photocopies, with related papers, 1945-1968. E.P. Abraham NCUACS 103/2/02 90 Publications D.76 Correspondence re Florey’s life, 1957-1969. D.77-D.89 Miscellaneous printed and typescript material, manuscript notes by Abraham and correspondencerelating to Florey’slife. Photographs in D.79. D.90, D.91 Article on Florey in A Biographical Dictionary of Scientists, London 1974. D.90 D.91 D.92 D.93 8pp manuscript draft and 2 typescript drafts, all with manuscript revisions. Correspondence re publication with further copy of typescript draft, 1972; copy of proof with manuscript corrections. Review for Nature 282, No. 5735 (Autumn Books Supplement, November 1979) entitled ‘Florey’s creative power: Howard Florey: The Making of a Great Scientist, by Gwyn Macfarlane, Oxford University Press 1979. Correspondencere publication andletter arising; 11pp copy of typescript of review and proof with manuscript corrections; re-print. Revised notice for Florey in Dictionary of National Biography 1986-1990, Oxford 1996. Copy of proof with manuscript revisions. D.94-D.99 Other obituaries and articles on Florey written before his death, 1950-1968. D.94 D.95 2pp typescript biographical notes on Florey for unknown publication, inscribed ‘1950’ on first page. ‘The New Provost of Queen’s’, Oxford (published by the Oxford Society), 1962. A short article on Florey following his election to the Provostship of Queen’s College. Correspondence re publication; 2pp typescript draft; proof with manuscript corrections. E.P. Abraham NCUACS 103/2/02 91 Publications D.96 D.97 Short article on Florey for ‘News and Views’, Nature, probably published in 1963. Copyof letter enclosing 1p typescript of article. Two 12pp typescript drafts with manuscript revisions and inserts, entitled ‘Stock obituary notice for The Times — 5 yearly revision’, ca 1955-ca 1965; off-print of published obituary in The Times, 1968. D.98 ‘H.W. Florey — Nobel Prize for Medicine and Physiology 1945’, 1968. 19pp copy of typescript obituary so entitled, probably written by Abraham. D.99 Correspondencere declined invitation to write obituary, 1968. D.100-D.102 Broadcasts on Florey by, or with a contribution by, Abraham. D.100 B.B.C. radio broadcast: ‘Obituary on Lord Florey’, by Abraham, recorded 1 March 1965. Correspondence re script, with contract; 2pp typescript draft script with manuscript corrections, inscribed ‘Oxford studio’. D.101 ‘Portrait of Lord Florey’, B.B.C. Radio Four, 28 March 1969. Abraham contributed an interview to the programme. The other speakers were Dr C.M. Fletcher, Dr Sanders, John Prestwich and Norman Heatley. Correspondence re preparations; contract; 4pp photocopy of typescript script, with manuscript corrections, inscribed ‘corrections put in by M[argaret] Florey’; photocopied scripts of other speakers on the programme; contract; 1p manuscript draft of a script, found with the other material in this folder and possibly relatedto it. Correspondence re plans for a possible archival film featuring Florey, Abraham and / or Norman Heatley, 1966, 1967. Miscellaneous correspondence etc with members of Florey’s family, re obituaries of Florey by Abraham and re other matters connected with his death, 1966-1969. D.102 D.103 E.P. Abraham NCUACS 103/2/02 92 Publications D.104, D.105 Miscellaneous correspondence and papers, mostly re publications (by individuals other than Abraham) and broadcasts on Florey andthe history of penicillin, 1968-1989. is a transcript, Included of an autobiographical tape recording by Florey, with manuscript corrections by Abraham. An inscription by Abraham on the first page states that the recording was made towardsthe end of Florey’slife. entitled ‘HWF on penicillin, of part Found with the material in D.33-D.103. 2 folders. D.106-D.113 Correspondence and papers re fundraising for a memorial stone to Florey in Westminster Abbey (unveiled 2 November 1981) and preparations for the unveiling ceremony, with correspondence arising. 1980-1983. A few photographs are included. Included at D.113 is brief correspondence re Abraham's preparation of his Royal Society Biographical Memoir of Florey, 1968. 8 folders. D.114 D.115 Obituary of Mary Ethel Hayter Florey, Lady Florey, by Abraham, British Medical Journal, 1966 or 1967. 2pp copy of typescript obituary and letter re publication, October 1966. ‘Behaviour of alpha-Aminoadipoyl and Glutamylcysteines in the Presence of Intact and Disrupted Mycelium of a Cephalosporium sp.’, with P. Bronwen Loder and G.G.F. Newton, Biochemical Journal 112, 1969. This paper appears to have incorporated another paper, ‘Synthesis and Some Properties of alpha-Aminoadipoyl and Glutamy Cysteines’, with P. Bronwen Loder, which wasinitially written separately. re submission of the 2 original papers; typescript drafts, Letter manuscript revisions, of the 2 papers. with D.116 Copy of typescript draft of combined paper with manuscript corrections; figures. E.P. Abraham NCUACS 103/2/02 93 Publications D.117 D.118 ‘Some Properties of Two Cell-bound Beta-lactamases from Bacillus cereus 569/H’, with S. Kuwabara, Biochemical Journal 115, 1969. 2 copies of typescript drafts with manuscript revisions; correspondence re publication. ‘Biosynthesis of Peptides containing alpha-Aminoadipic Acid and Cysteine in Extracts of a Cephalosporium sp.’, with P. B. Loder, Biochemical Journal 123, 1971. First page of typescript of article; letter re submission of the paper. D.118A ‘Specificities of Haemagglutinating Antibodies Evoked by Members of the Cephalosporin C Family and Benzylpenicillin’, with J.M.T. Hamilton-Miller, Biochemical Journal 123, 1971. Proof with manuscript corrections. D.119 D.120 Review for unknown publication: Yeast Mould and Plant Protoplasts, edited by J.R. Villanueva et a/., New York 1973. 2pp typescript draft with manuscript corrections; proof. and Draft paper with the draft title ‘On the (role / involvement) of microbial penicillin- biosynthesis (mechanism) of Beta-lactam antibiotics’. The authors wereoriginally given as Abraham and E.J. Vandamme, though Abraham’s name has been crossed out. Inscribed ‘summer ’73 Oxford Univ’. cephalosporin- acylases and / in the Copy of 37pp manuscript (hand other than Abraham’s) and typescript draft, with manuscript revisions by Abraham. D.121-D.123 Articles contributed by Abraham to Methods in Enzymology, Vol. 30, New York 1974. D.121 ‘Acetyl Esterase, a Citrus Enzyme’, with P.A. Fawcett. Correspondencere preparation of paper; 7pp typescript draft with extensive manuscript revisions; later typescript draft and revised (or final) version. E.P. Abraham NCUACS 103/2/02 94 Publications D.122 ‘5-(a-Aminoadipyl)cysteinylvaline Synthetase’, with P.A. Fawcett. 6pp typescript and proof with manuscript corrections. D.123 Correspondencere publication, with a few miscellaneous papers. D.124 ‘Biosynthesis and Enzymic Hydrolysis of Penicillins and Cephalosporins’, University of Tokyo Press 1974. Paper resulting from an E.R. Squibb Lecture. 35pp copy of typescript with references and figures. D.125 D.126 D.126A D.127 of ‘Synthesis N, Aminopenicillanic Acid’, with J.J. Usher and P. Journal 151, 1975. Tritium-labelled Isopenicillin Penicillin 6- B. Loder, Biochemical and N Letter re publication of this paper and the one described in D.126; first page of copy of typescript article; proofs with manuscript corrections. ‘Behaviour of Tritium-labelled Isopenicillin N and 6-Aminopenicillanic Acid as Potential Penicillin Precursors in an Extract of Penicillium chrysogenum, with P. A. Fawcett and J.J. Usher, Biochemical Journal 153, 1975. First page of copy of typescript article; proof with manuscript corrections. ‘Biosynthesis of Biosynthesis IV: The Chemical Society Specialist Periodical Reports. Penicillins and Cephalosporins’, with A. P. Fawcett, 34pp copy of typescript of paper with references, figures etc; proof with manuscript corrections. ‘Synthesis of 5-(a-Aminoadipyl) cysteinylvaline and its Role in Penicillin Biosynthesis’, with P. A. Fawcett, J. J. Usher, J. A Huddleston, R. C. Bleaney, J. J. Nesbitt, Biochemical Journal 157, 1976. Correspondence re publication; 32pp copy of typescript draft with manuscript corrections. E.P. Abraham NCUACS 103/2/02 95 Publications D.128 D.129 D.130 Review for The Times Literary Supplement entitled ‘Bad newsfor bacteria’, 17 December 1976: Penicillin in Perspective, by David Wilson, London 1976. Correspondence re publication; typescript draft with extensive manuscript revisions and 6pp corrected version; copy of proof; off-print. Review for The Times Literary Supplemententitled ‘The Molecular Key’, 12 August 1977: New Worlds in Chemistry, London 1976. Correspondence re publication; 4pp copy of typescript of review; off-print. ‘The Stereochemistry of B-lactam Formation in Cephalosporin Biosynthesis’, with J. A. Huddleston et a/., Biochemical Journal 169, 1978. 11pp copy of typescript draft with manuscript revisions. D.131-D.177 Articles by Abraham on Ernst Boris Chain arising from the latter's death in August 1979. Included at D.172-D.177 are papers relating to a symposium held on the occasion of Chain’s 70th birthday. See D.228-D.230 for material relating to Abraham’s notice for Chain in the Dictionary of National Biography. D.131 Obituary for the Biochemical Society Bulletin Vol.1, no.5, 1979. Correspondence re publication and 4pp copy of typescript of obituary; off- print and copy ofre-print. D.132 D.133 Correspondence re obituary by Abraham for The International Journal of Environmental Studies, September-October 1979. 2 copies of typescript obituaries probably by Abraham, one with annotations by him, for unknown publications. D.134 Article on Chain in A Biographical Dictionary of Scientists, London 1982. Correspondence etc re publication and 3pp copy of typescript ofthe article. E.P. Abraham NCUACS 103/2/02 D.135-D.170 D.135-D.141 96 Publications ‘Ernst Boris Chain’, Biographical Memoirs of Fellows of the Royal Society, 29, 1983. Correspondence etc re preparation and drafting of the memoir, 1979-July 1983. Included are a few letters re Abraham’s assistance to others compiling publications on related topics and re other matters such as arrangementsfor the cataloguing of Chain’s papers; and 3 photographs at D.141, including one of Chain in later years (inscribed ‘1976’ on back). 7 folders. D.142-D.159 Drafts of the Memoir. D.142-D.145 Extensive and detailed manuscript notes on Chain’s life and career extracted from cited correspondence and other documentary sources. 4 folders. D.146-D.148 Early manuscript draft, apparently incomplete, with extensive revisions. (paginated 1-98, with gaps). 3 folders. D.149-D.152 Typescript draft inscribed ‘1st Draft’ with manuscript revisions. Paginated 1-60. 4 folders. D.153-D.158 Copy of later typescript draft, with bibliography etc, probably the draft circulated to various individuals for comment. At D.158 is a page of typescript suggested alterations to the text inscribed ‘Trevor Williams’, with manuscript annotations by Abraham. D.159 A few typescript and manuscript pages from draft (or drafts), different to those described in D.146-D.158; drafts of figures; a few miscellaneous manuscript notes. E.P. Abraham NCUACS 103/2/02 97 Publications D.160 Re-print of the Memoir. D.161-D.163 Correspondencearising from publication of the Memoir, mostly letters of thanks from membersof the scientific community and friends in receipt of a copy, with congratulations and comments, 1983, 1984, with a few letters 1985-1988. Included are a few letters re Abraham’s assistance to others compiling publications on related topics. 3 folders. D.164-D.170 Typescript and printed background material and correspondence, used in the preparation of the Memoir. D.164 Correspondence between Abraham and Chain mostly in connection with the former's preparation of the Royal Society Biographical Memoir of Florey, 1969. Included is a copy of a funding application made by the Sir William Dunn School to the Rockefeller Foundation in 1939 which is the subject of the correspondence. D.165 Copies of correspondence of Chain, 1969-1976. Letters by Chain to Sir Bernard Katz in which Chain complains of lack of recognition in Britain, 1969. Correspondence with Government ministers and leading scientists re issues in biochemical and general scientific research, 1971-1976. Correspondencere controversies at Imperial College London, 1974, 1977. Correspondence with Sir Robert Robinson, mostly re the history of penicillin, March-May 1974. D.166 Correspondence, mostly between Abraham and Sir Robert Robinson, concerning claims made by Chain about his role in the development of penicillin, April 1974-January 1975; 2 unrelated letters by Abraham and Chain (copy), 1969, 1979 (found with the other materialin this file). E.P. Abraham NCUACS 103/2/02 D.167-D.170 98 Publications Miscellaneous typescript and printed material (some photocopies) and manuscript career and the developmentof penicillin. notes by Abraham relating Chain’s to 4 folders. D.171 Stock obituary of Chain for The Times. Correspondencere offer to write obituary and acceptance, and re drafting, November 1972-January 1973, and 4pp typescript draft of notice with manuscript revisions; copy of revised (or final) typescript version. D.172-D.177 ‘Biologically Active Substances — exploration and exploitation’, a symposium to mark Chain’s 70th birthday held at the Royal Society, 15, 16 June 1976. The papers relating to this event, at which Abraham gave a paper, were found with the material in D.135-D.170. D.172, D.173 Correspondence re arrangements, with programme etc, and a few letters arising, 1975, 1976. 2 folders. D.174-D.177 ‘The Biosynthesis of B-lactam Antibiotics’, Abraham’s paper. D.174 14pp manuscript draft with revisions; 2 typescript drafts, one incomplete, with manuscript revisions; copy of 2pp typescript outline. D.175 Copy of typescript corrected version. D.176, D.177 Publication Exploration and Exploitation, edited by D.A. Hems, Wiley 1977. of Abraham’s paper in Biologically Active Substances — Correspondence re publication, 1976, 1977, and proof of Abraham’s paper with manuscript corrections. 2 folders. E.P. Abraham NCUACS103/2/02 99 Publications D.178 D.179 D.180 D.181 D.182 ‘Transport and Metabolism of Bacilysin and Other Peptides by Suspensions of Staphylococcus aureus, with D. Perry, Journal of General Microbiology 115, 1979. Proof with manuscript corrections. ‘Incorporation of °H from 6-(L-a-Amino[4,5-°H]adipyl)-L-cysteinyl-D-[4,4- SH]valine into Isopenicillin N’, with Joseph O’Sullivan, Roger C. Bleaney and J. A. Huddleston, Biochemical Journal 184, 1979. Proof with manuscript corrections. Review for Endeavour, [?1979]: isolation, separation and purification’, Journal of Chromatography Library Vol. 15, edited by M.J. Weinstein and G.H. Wagman, [?1978]. ‘Antibiotics: Correspondence re publication; 2pp typescript of review with manuscript corrections. ‘A Spectroscopic Study of Metal lon and Ligand Binding to B-Lactamase II’, with G. S. Baldwin, Alphonse Galdes, H. A. O. Hill and S. G. Waley, Journal of Inorganic Biochemistry 13, no.3, 1980. 17pp copy of typescript draft (with reference, figures etc) with manuscript corrections. ‘Penicillin Biosynthesis: Conversion of Deuterated 5-(L-a-Aminoadipyl) - L — Cysteinyl of Cephalosporium acremonium’, Chemical Communications 1981. Isopenicillin N by a Cell-free al, - D - Valine to with J. Extract E. Baldwin et 5pp copyof typescript draft. D.183-D.189 ‘The B-lactam Antibiotics’, Scientific American 244, No.6, 1981. D.183 Correspondence re publication, February-May 1981. Included a few letters, 1979, concerning other matters. D.184 Correspondencearising, July-October 1981. E.P. Abraham NCUACS 103/2/02 D.185 100 Publications 28pp typescript Cephalosporins and Their Successors’. notes. manuscript draft with revisions ‘Penicillins, Included are a few manuscript entitled This appears to be an early draft of ‘The B-lactam Antibiotics’. D.186 Revised version of the draft in D.185 (with the sametitle). D.187, D.188 D.189 D.190 Draft drawings and photographic illustrations, some with annotations on back, others mounted on to annotated cards; manuscript notes and drafts for captions; typescript drafts of captions, with manuscript revisions. prints for 2 folders. Off-print. ‘Conversion of Penicillin N in Cell-free Extracts of Cephalosporium acremonium, with G.S. Jayatilake and J.A. Huddleston, Biochemical Journal 194(part 2), 1981. Isopenicillin N into Copy of 12pp typescript draft with manuscript corrections. D.191-D.195 ‘Biosynthesis of B-Lactam Antibiotics’, with J. O’Sullivan, in Antibiotics IV: ‘Biosynthesis’, ed. by J.W. Corcoran, Berlin 1981. D.191 Correspondencere publication, 1978-1980. D.192-D.194 30pp typescript draft (with references, figures etc) with manuscript revisions. 3 folders. D.195 Proof with manuscript corrections. E.P. Abraham NCUACS 103/2/02 101 Publications D.196 ‘Biosynthesis of Penicillins and Cephalosporins in Cell-free Systems’, with J. O’Sullivan and J.A. Huddleston, Philosophical Transactions of the Royal Society, 1980 or 1981. 6pp copyof typescript with biographical note on Abraham. D.197-D.208 ‘Isolation and Properties of an Inducible and a Constitutive B-Lactamase from Pseudomonas aeruginosa, with M. Berks and K. Redhead, Journal of General Microbiology, 1982. Various drafts and other material re the preparation and publication of this paper. Contents of4 files. D.197-D.201 Contents ofa file. D.197 Correspondencere preparation and publication of the paper, 1978-1981. D.198-D.201 Typescript and manuscript drafts and reports, one headed with manuscript corrections. 4 folders. D.202 Typescript draft of report headed ‘Paper II’ with manuscript corrections. Contents of file. D.203-D.205 Contents of a file. D.203, D.204 Typescript drafts, some incomplete, with manuscript corrections, and figures. 2 folders. D.205 Figures with manuscript annotations, photographic prints and manuscript notes. D.206-D.208 Contents ofa file. D.206 Typescript draft with manuscript revisions. E.P. Abraham NCUACS 103/2/02 102 Publications D.207 Later typescript drafts (submitted for publication) and brief correspondence re publication, 1981. D.208 Proof. D.209 ‘Inhibition of Glucosamine Synthetase by Bacilysin and Anticapsin’, by H. Chmara, Journal of General Microbiology, [71984]. A paper wasrevised by Abraham prior to publication. Found with the material in D.197-D.208. Letter re publication, 1984; copy of typescript draft, with manuscript revisions by Abraham, andfigures. D.210 ‘Stoichiometry of Oxygen Consumption in the Biosynthesis of Isopenicllin N from a Tripeptide’, with R. L. White et a/, Biochemical Journal 203, 1982. Correspondence article; correspondence re publication of a later paper in the Biochemical Journal, 1984. 8pp copy of typescript re publication; of D.211 D.212 D.213 Copy of typescript of a paper entitled ‘Penicillin Biosynthesis: Oxygen Stoichiometry of Isopenicillin N Synthesis in a Cell-free System’, with R. L. White et a/, on which is inscribed the same publication reference as for the paper described in D.210. The texts of the articles are different; the authors are the same. ‘Penicillin Biosynthesis. Dual Pathways from a Modified Substrate’, with R. M. Adlington et al, Journal of Chemical Studies: ‘Chemical Communications’, 1983. 5pp copyof typescript of paper; 3pp manuscript notes found with typescript. ‘Conversion of '’0/'°O Labelled 8-(L-a-Aminoadipyl)-L-cysteinyl-D-valine to 70/"8O Labelled Isopenicillin N in a Cell-free Extract of Cephalosporium acremonium, with R. M. Adlington et al, Tetrahedron 39, 1983. 8pp copyof typescript of paper, with figures. E.P. Abraham NCUACS 103/2/02 103 Publications D.214, D.215 ‘Stereochemistry of the Incorporation of the Methyl Groups of ‘Chiral Methyl Valine’ into Methylene Groups in Cephalosporin C’, with C.-P. Pang etal, Journal of Chemical Studies: ‘Chemical Communications’, 1983. D.214 Letter re preparation; 23pp photocopy of typescript draft with manuscript revisions. D.215 Copyof typescript draft with revisions (later than those in D.214). D.216-D.220 ‘History of B-lactam Antibiotics’, a chapter in Handbook of Experimental Pharmacology, Vol. 67/1: Antibiotics Containing the Beta-Lactam Structure, Part 1, edited by A.L. Demain and N.A. Solomon, Berlin 1983. D.216 D.217 Correspondenceetc, mostly re preparation and publication, 1979-1984. 34pp copy of typescript draft of Abraham’s chapter,with letter. D.218, B.219 Copy of typescript draft with manuscript revisions. Stamped ‘23 Nov. 1982’ onfirst page. 2 folders. D.220 Proof andoff-print. D.221, D.222 ‘Purification Biochemical Journal 222, 1984. of Isopenicillin N Synthetase’, with C.-P. Pang et al., D.221 20pp copy of typescript, with figures, and correspondence re publication; manuscript notes (hand other than Abraham’s). D.222 Proofs with manuscript corrections. E.P. Abraham NCUACS 103/2/02 104 Publications D.223 D.224 ‘Stereochemistry of Methyl Groups into Methylene Groups in Cephalosporin C’, C.-P. Pang et al., Biochemical Journal 222, 1984. Incorporation the of Valine Correspondencere publication; proof with manuscript corrections. Review article entitled ‘Benefactors’ Benefactor for The Times Literary Supplement, 27 January 1984: The Legacy of Alfred Nobel: The Story Behind the NobelPrizes, by Ragnar Sohlman, London 1983. Correspondencere publication; 7pp copy of typescript draft of review; proof; off-print. D.225, D.226 Review entitled ‘The Shooter and the Shot’: Alexander Fleming: The Man and the Myth, by Gwyn Macfarlane, London 1984. The review was published in a special supplement by Nature, ‘Spring Books’, April 1984. D.225 D.226 D.227 Copy of 9pp typescript ‘first draft’ with manuscript revisions; copy of revised draft and copyof off-print; correspondence re publication. Letter to Abraham from Max Perutz, December 1985, enclosing a copyofhis review of Macfarlane’s book, entitled ‘Lucky Alec’, for comment. On Perutz’s typescript are minor manuscript annotations by Abraham. Review for FEBS Letters, [?May] 1984: The Target of Penicillin. The Murein Sacculus of Bacterial Cell Walls. Architecture and Growth, edited by R. Hakenbecketa/., Berlin 1983. Correspondencere publication and 2pp copyof typescript of review. D.228-D.234 Contentsoffile inscribed ‘Oxford University Press’. D.228-D.230 Notice for Ernst Chain in Dictionary of National Biography 1971-1980, Oxford 1986. For the main body of papers relating to Abraham’s articles on Chain see D.131-D.177. D.228 Correspondence mostly re the invitation including press copyof the article, 1985, 1986. to contribute and publication, E.P. Abraham NCUACS 103/2/02 105 Publications D.229 D.230 6pp manuscript draft with revisions; 9pp typescript draft with manuscript revisions. Copy of revised typescript draft with further manuscript revisions; copy of version sent to publishers. D.231, D.232 Notice for Sir Harry Jephcott in Dictionary of National Biography 1971-1980, Oxford 1986. D.231 D.232 Correspondencere preparation and publication, December 1984-1985, and 1 letter arising, 1989. 7pp typescript draft with manuscript corrections; copy of typescript inscribed ‘Edited version’; background material. D.233, D.234 Correspondence with Oxford University Press re Abraham’s involvementin various publications, 1979-1991. D.233 Correspondencere proposed book on penicillin by Abraham, 1979, 1980. No definite plans for the book emerge from this correspondence. D.234 Miscellaneous correspondenceetc, 1985-1991. Relates to Abraham’s advisory role in various publications including the History of the University of Oxford, Oxford 1992. D.235-D.240 Chapter for proposed book The Cephalosporin Antibiotics. The title of Abraham’s chapter was ‘Cephalosporins 1945-1985’. The publishers, Adis Press Ltd (New Zealand), eventually abandonedpublication of the book. The material was published instead in a special supplement to Adis Press’s international supplement Drugs, 1987. D.235-D.237 Correspondence etc re proposed publication and proof of the chapter (at D.237), 1984-1986. 3 folders. E.P. Abraham NCUACS 103/2/02 Publications D.238 34pp copyof typescript draft of the chapter, with referencesetc. Correspondence re supplement Drugs, and proof with manuscript corrections, 1987. of Abraham’s original chapter in publication 2 folders. D.239, D.240 D.241 106 the and of an ‘Purification with Deacetoxycephalosporin C Synthetase and Hydroxylase Activities’, with J. E. Baldwin et al., Biochemical Journal 245, 1987. Characterization Enzyme Initial Typescript draft with manuscript revisions; 31pp copy of typescript revised version andfigures. D.242-D.245 ‘Factors Affecting the Isopenicillin N Synthetase Reaction’, with D. Perry and J.E. Baldwin, Biochemical Journal 255, 1988. D.242 D.243 D.244 D.245 D.246 Correspondencere preparation and publication, 1987, 1988. Typescript and manuscript draft of the article, with extensive manuscript revisions. 2 typescript drafts with manuscript revisions, one including manuscript drafts of figures. 17pp copy of typescript inscribed ‘copy for press’, with figures etc. ‘Acyl Coenzyme A: from Penicillium chrysogenum and Aspergillus nidulans’, with P.A Whiteman et al., FEBS Letters 262, 1990. 6-aminopenicillinanic Acyltransferase Acid Typescript draft with manuscript revisions and inserts; 6pp typescript revised version inscribed ‘Final copy revised’, with figures. E.P. Abraham NCUACS 103/2/02 107 Publications D.247-D.250 ‘Selective Reminiscences of B-lactam Antibiotics. Early Research on Penicillin and Cephalosporins’, for ‘Roots’ column, BioEssays: Advancesin Molecular, Cellular and Developmental Biology, Vol. 12, No.12, December 1990. The ‘Roots’ column presented first-hand accounts of key discoveries or breakthroughsin the biological sciences. D.247 D.248 Correspondence re publication with 18pp copy of amended[?final] typescript of article. 17pp manuscript draft of article with revisions and 1p manuscript notes; typescript draft with manuscript revisions. D.249 Copyof revised typescript version. D.250 Off-print. D.251, D.252 Review for Nature, published 1990: Miracle Cure. The Story of Antibiotics, by Milton Wainwright, Blackwell 1990. D.251 D.252 6pp typescript draft with extensive manuscript revisions; copy of revised version. Brief correspondence etc corrections. re publication and proof with manuscript D.253-D.270 Undated publications. D.253 ‘Possible Intermediates in the Biosynthesis of Cephalosporin’, with G.G.F. Newton. Copyof 11pp typescript draft so entitled, with manuscriptcorrections. D.254 ‘The Cephalosporins’. Copy of 8pp typescript draft with manuscript revisions. E.P. Abraham NCUACS 103/2/02 108 Publications D.255 ‘EnzymesInvolved in the Biosynthesis of Cephalosporin C.’ Copy of 7pp typescript draft, so entitled, with manuscript corrections. D.256 ‘Biosynthesis of Penicillins and Cephalosporins’, with G.G.F. Newton. Copy of 40pp typescript draft, with manuscript corrections, and index of subjects. D.257, D.258 ‘B-Lactamases and their Rdéle in Resistance to B-Lactam Antibiotics’. 58pp copyof typescript draft so entitled, with figures. 2 folders. D.259-D.265 Untitled manuscript and typescript draft of a book on antibiotics, with extensive manuscript revisions, n.d. Thedraft is divided into sections or chapters on particular antibiotics. 7 folders. D.266-D.270 Miscellaneous material relating to unidentified publications, or possible publications, by Abraham, n.d. The material mostly consists of parts of manuscript and typescript drafts and notes. 5 folders. D.271-D.288 EDITORIAL CORRESPONDENCE 1948-1998 Correspondenceand papersre refereeing of papers intended for publication, generaleditorial business and publications by Abraham. Shorter correspondenceis at D.284-D.288. E.P. Abraham NCUACS 103/2/02 109 Publications D.271-D.274 The Biochemical Journal 1949-1988 Abraham servedon the Editorial Board, ca 1955-1960. Included is correspondence re publication of papers by Abraham in the Journal found with the editorial correspondence. 4 folders. D.275, D.276 Elsevier Publishing Company 1960-1964 Correspondence, Publishing Company, re Comprehensive Biochemistry, edited by Marcel Florkin and Elmer H. Stotz, Elsevier 1962. including Elsevier re-print, mostly with Abraham wrote a chapter for Volume 2. 2 folders. D.277-D.281 Tagournal of Antibiotics 1988-1998 Abraham was an Emeritus Member. Mostly re the business of the Editorial Board. 5 folders. D.282 Pharmacological Reviews 1960-1962 Correspondence re review by Abraham of a book The Cephalosporins for Pharmacological Reviews 14, 1962. D.283 Sherry F. Queener 1983-1987 Correspondence etc mostly with Sherry F. Queener re Beta-Lactam Antibiotics for Clinical Use, edited by Queener et a/., New York 1986. Abraham contributed a chapter to the book. E.P. Abraham NCUACS 103/2/02 110 Publications D.284-D.288 Shorter correspondence 1948-1998 Arranged chronologically. 5 folders. THE ROYAL COMMISSION ON HISTORICAL MANUSCRIPTS Report on the correspondence and papers of SIR EDWARD PENLEY ABRAHAM (1913-1999) biochemist in Bodleian Library, Oxford VOLUMEII Reproduced for the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS103/2/02) by The Royal Commission on Historical Manuscripts Quality House, Quality Court, Chancery Lane, London WC2A 1HP 2002 All rights reserved No 9/02 NRA 43883 Catalogue of the papers and correspondenceof Sir Edward Penley Abraham FRS (1913 - 1999) VOLUME II Section E: Lectures and broadcasts Section F: Visits and conferences Section G: Societies and organisations Section H: Correspondence Index of correspondents by Simon Coleman, Peter Harper and Caroline Thibeaud NCUACScatalogue no. 103/2/02 E.P. Abraham NCUACS 103/2/02 114 SECTION E LECTURES AND BROADCASTS E.1-E.63 E.1-E.52 LECTURES E.53-E.63 BROADCASTS E.P. Abraham NCUACS103/2/02 — 112 Lectures and broadcasts E.1-E.52 LECTURES 1942-1993, n.d. E.1-E.22 Lectures associated with teaching E.23-E.52 Public lectures For further papersrelating to lectures see Section F. E.1-E.22 Lectures associated with teaching 1942-1973, n.d. E.1-E.21 Lectures on pathology given by Abraham at the University of Oxford. E.1, E.2 Copiesof lecture or course handouts for students, 1942-1951, n.d. 2 folders. E.3-E.8 Contents of 2 files inscribed ‘Lectures — School of Pathology’. Lectures by Abraham to students at the Oxford University Department of Pharmacology from 1957 or earlier. E.3-E.5 Manuscript and typescript notes and drafts for various lectures, ca 1957-ca 1971, n.d. Most sets of notes havetitles. At E.3 are a page inscribed ‘1957’ and three sets of notes which appear to relate to a card containing a list of lecturetitles dated 1962. A few photographs are included at E.4. 3 folders. E.6 E.7 Letters (invitations and acceptance) re proposed lectures by Abraham in early 1970 and early 1971. Typescript entitled ‘Haemostasis and Thrombosis’, inscribed ‘Pathology 1971 New Class Sheets’. E.P. Abraham NCUACS 103/2/02 113 Lectures and broadcasts E.8 Re-prints of various lectures and papers by Abraham, 1958-1966, n.d. Found with the material in E.3-E.5 and apparently unrelatedto it. E.9-E.20 ‘Lectures on General Pathology’, contents of hard-back binder. Copies of typescripts of lectures, most, or all, by Abraham, many with manuscript revisions. First page (list of contents) inscribed as above. A numberofthe lecture titles correspond to those of some pagesof notes and drafts in E.3-E.5. Some of the texts include inserted pages of manuscript notes. Most of the material shows continuous pagination (with gaps) and division into chapters, indicating that many or all the lectures formed part of a publication. 12 folders. E.21 Hardback notebook containing notesfor various lectures, n.d. Inscribed ‘E.P Abraham Sir William Dunn School of Pathology Oxford’ inside cover. E.22 University of Bath seminars, 1970-1973. Abraham spokeat seminars for staff and research students. Correspondence re arrangements for 3 seminar talks in 1970, 1972 and 1973. E.23-E.52 Public lectures ca 1960-1993, n.d. Arranged chronologically, though some miscellaneous material at E.37-E.45 has not been incorporated into the chronological sequence. Material relating to undatedlectures is at E.46-E.51. Invitations declined are at E.52. E.23-E.25 First ‘ONR’ Lecture (banquet speech) by Abraham at the Annual Meeting of the Society for Industrial Microbiology, Northwestern University, Evanston, Illinois, USA, 19-24 August 1973. The title of the speech was ‘Some Aspects of the Development of the Penicillins and Cephalosporins’. E.P. Abraham NCUACS 103/2/02 114 E.23 E.24 E.25 Lectures and broadcasts Correspondencere arrangements and arising, May-February 1974. 29pp typescript draft of lecture with manuscript revisions; 22pp copy of typescript of the lecture. The lecture was published in Developments in Industrial Microbiology Volume 15. Copy of Society of Industrial Microbiology Newsletter, July 1973, containing programmeetc for the Annual Meeting 1973 and a short biography of Abraham; a few miscellaneous papers found with the material relating to the ‘ONR Lecture’. E.26-E.28 Lecture by Abraham given at the Technische Universitat Berlin, Germany, 4 June 1982. The lecture was within the framework of the University’s research branch ‘Structure, Function and Biosynthesis of Peptides and Proteins’. E.26 E.27 E.28 Correspondenceetc re arrangements and arising, March-June 1982. 18pp typescript draft of lecture, with manuscript corrections, headed‘Berlin’; 2pp of typescript and manuscript notes. Other correspondence arising from Abraham’s association Technische Universitat, January-November 1982. with the E.29, E.30 Squibb lecture, University of Nottingham, 12 May 1983. E.29 E.30 Correspondencere arrangements andarising, July 1982-May 1983. ‘The Cephalosporins — origins and future’. 2pp incomplete manuscript draft of Abraham’s lecture so entitled, with revisions; 1p manuscript draft entitled ‘Slides’ and typescript pages for use as slides. E.P. Abraham NCUACS 103/2/02 115 Lectures and broadcasts E.31-E.33 Lecture by Abraham given at the Technische Universitat Berlin, Germany, 24 June 1983. The lecture was in the framework of the University’s research branch ‘Structure, Function and Biosynthesis of Peptides and Proteins’. E.31 E.32 E.33 E.34 Correspondenceetc re arrangements and arising, March-November 1983. 20pp typescript draft with manuscript revisions; 15pp typescript revised version with manuscript annotations and 1p manuscriptlist of slides. 19pp manuscript notes with copies of figures, probably related to the drafts described in E.32. Talk given to the Southampton Medical Society, (arranged for) 2 October 1991. The lecture was on the origins and developments of cephalosporins. penicillins and Correspondencere invitation and arrangements, February-July 1991. E.35, E.36 Lecture given at the National Portrait Gallery: ‘Alexander Fleming and his Remarkable Discoveries’, 31 March 1993. E.35 Correspondencere arrangements and arising, October 1992-April 1993. Included is correspondenceetc (found with the above correspondence) rea proposed Fleming Museum in St Mary’s Hospital, October 1992-February 1993. E.36 12pp incomplete manuscript draft with revisions; incomplete typescript draft with and photocopied material used asslides. manuscript typescript revisions; revised draft with prints E.37-E.45 Contents of a file entitled ‘Miscellaneous lectures’. E.P. Abraham NCUACS 103/2/02 116 Lectures and broadcasts E.37 E.38 E.39 E.40 E.41 E.42 E.43 E.44 20pp typescript draft, with manuscript revisions, entitled ‘Mode of Action of Antibiotics’; 9pp typescript headed ‘Canberra’; 19pp copyof a typescript entitled ‘The Impact of Antibiotics on Medicine’; revised version of the latter, probably for publication. manuscript revisions, draft, with From file inscribed ‘Lectures — Australia’. The lectures were probably given at the International Symposium on the Chemistry of Natural Products, Australia, 15-25 August 1960 (see F.2). ‘Some Aspects of Resistance to Antibiotics’, given at a seminar on infectious disease organised by the Oxford Regional Committee for Postgraduate Medical Education and Training, 16 February 1971. Correspondence re arrangements, August-November 1970; 6pp manuscript notes for lecture; 17pp typescript draft of lecture, with manuscript revisions, and 4 typescript pages (probably usedforslides). 3pp incomplete headed ‘Orthopaedic Centre March 1st 1975 and 3pp manuscript notes for the remainder of the lecture. manuscript typescript revisions, draft, with ‘Beta-Lactam Antibiotics: A Brief Modern History’, lecture given at the 9th International Congress of Chemotherapy, Royal Albert Hall, London, 13-19 July 1975. 12pp copy of typescript of the lecture; programmeetc. 25pp typescript of lecture entitled ‘The Cephalosporins’, inscribed ‘History of Science April 1976’, with 1p manuscriptlist of slides; 3pp typescript notes for the lecture with manuscript annotations. 21pp copy of typescript of lecture entitled ‘Cephalosporin’, inscribed ‘50th Anniversary April 1977, with 2pp typescript of speech introducing Abraham. 7pp typescript Contributions to Antibiotics and Progress in Chemotherapy’, n.d. with manuscript revisions draft entitled ‘Some British Miscellaneous manuscript and typescript notes andlists of slides etc, with 2 photographs, for unidentified lectures, n.d. E.P. Abraham NCUACS 103/2/02 117 Lectures and broadcasts E.45 Miscellaneous correspondence, mostly re arrangements andarising, relating to various lectures, 1960-1985; typescript of article entitled ‘The Penicillin Nucleus’ and ‘inscribed 14 March 1959’, with letter re its publication in the British Medical Journal, 1959 (found with the other material in this folder). E.46-E.51 Undated lectures. E.46 Contentsofa file entitled ‘Lectures — Biochemistry’. Manuscript notes for 2 lectures entitled ‘Sequence of Amino Acids in Proteins’ and ‘Hypertension’. N.d. E.47 ‘The Chemistry of the Penicillins’. 24pp copyof typescript so entitled with manuscript diagrams, n.d. E.48-E.51 Contents ofa file inscribed ‘Ceph-Pen structures photographs’, n.d. E.48 Incomplete untitled 11pp manuscript draft with 4pp manuscript diagrams and notes; incomplete untitled 8pp manuscript draft. E.49-E.51 Figuresfor slides etc (mostly photographs). 3 folders. E.52 Invitations declined, 1988, 1991. E.53-E.63 BROADCASTS 1962-1991, n.d. E.53-E.60 Contents of a file inscribed ‘BBC’. E.53 BBC interview (Abraham and Guy Newton) on the subject of Cephalosporin for a television programme. Correspondence re arrangements and arising, November 1962-January 1963. E.P. Abraham NCUACS 103/2/02 118 Lectures and broadcasts E.54 E.55 E.56 E.57 E.58 4pp copyof transcription (probably incomplete) of monologue by Abraham on Howard Florey and the development of penicillin from a radio programme, 17 December 1968. Correspondence re Abraham’s assistance in research for a BBC Open University chemistry programme, June 1977. ‘Antibiotics — a Failing Weapon?’, BBC World Service, 21 September 1977. Abraham spoke about Brétzu’s discovery of cephalosporium. 10pp typescript of programme script and copy of contract. Correspondence re a proposed BBC radio programme on the discovery penicillin. October 1979. ‘Breakthrough’ No.4: Howard Florey, broadcastin 1983. A film in a documentary series on great medical figures. Abraham made a brief (non-speaking) appearancein the film and assisted in checking the script andin filming at the Sir William Dunn School of Pathology. Brief correspondence re preparation and arising and draft script with manuscript revisions and annotations by Abraham, August-December 1982. E.59 Horizon documentary about penicillin: ‘The Mould, the Myth and the Microbe’, 27 January 1986. Letters re Abraham’s contribution to the programme, 1985, 1986. E.60 Letters in connection with an interview Abraham gave to Radio Oxford, n.d. E.61, E.62 ‘The Cephalosporins’, an educational film apparently made by E.R. Squibb & SonsLtd to increase understanding of the cephalosporin group of antibiotics. Abraham assisted in the making of the film and contributed a historical introduction to it. E.P. Abraham NCUACS 103/2/02 119 Lectures and broadcasts E.61 E.62 E.63 Correspondencere preparations andarising, with 2 typescript draft scripts of Abraham’s introduction and amended version. November 1974-January 1975. 2pp typescript draft script of preamble (introducing Abraham); 14pp copyof typescript programmescript with manuscript revisions by Abraham. Brief correspondence re arrangements for an interview which Abraham agreedto give to Fulcrum Productions Ltd, April, May 1991. E.P. Abraham NCUACS 103/2/02 120 SECTION F VISITS AND CONFERENCES F.1-F.89 The material covers the period 1955-1995 and is arranged chronologically. Papers relating to undated and unidentified visits are at F.88, F.89. See Section H for substantial further material relating to visits and conferences. E.P. Abraham NCUACS 103/2/02 121 Visits and conferences F.14 F.2 3éme Congrés International de Biochimie, Brussels, Belgium, 1-6 August 1955. Abraham, with I.M. Lockhart gave a lecture ‘Hydrogenolysis of bacitracin’ and, with Guy Newton, ‘Antibacterial peptides related to penicillin’. Copyof printed ‘Résumés des Communications’ (abstracts of the lectures). International Symposium on the Chemistry of Natural Products, Melbourne, Canberra and Sydney,Australia, 15-25 August 1960. The symposium was organised by the Australian Academy of Science and held under the auspices of the International Union of Pure and Applied Chemistry (IUPAC). lecture ‘Degradation of cephalosporin C’. Abraham, with Guy Newton, gave a_ Copy of Symposium Handbook interleaved with pages of rough manuscript notes, some in Abraham's hand; copy of book of Abstracts of Papers, on 2pp of which (including inside back cover) are manuscript notes by Abraham; 2 loose pages of manuscript notes. See E.37, H.335-H.340 for related material. F.3 Conference (Gordon research Conference) on Medicinal Chemistry, Colby Junior College, New London, New Hampshire, USA, 30 July-3 August 1962. Abraham gave a lecture ‘Biochemical and Microbiological Studies on Derivatives of 7-Amino-cephalosporanic Acid’. Programme with manuscript notes by Abraham on a number of pages; letter arising, July 1962. See also H.451, H.452. F.4 Cephaloridine Conference, New College Oxford, 13-16 March 1967. The conference was arranged jointly by the Fellowship of Postgraduate Medicine and Glaxo Laboratories Ltd. Abraham chaired one session for which he gavea short introductory speech. re arrangements, with programmes; 1p copy of Letter of Abraham's speechentitled ‘Cephaloridine — Historical Remarks’; 1p copyof typescript of Guy Newton’s speech from the same session. typescript E.P. Abraham NCUACS 103/2/02 122 Visits and conferences F.5-F.10 Visit to the USA,April 1967. Abraham wasinvited to give lectures at the University of Wisconsin (one of a series of Rennebohm Lectures) and at a ‘Penicillins and Cephalosporins’ symposium held during the annual meeting of the American Academy of Pharmaceutical Sciences in Las Vegas. The papers described below were the contents ofa single file. F.5, F.6 Rennebohm Lecture by Abraham, University of Wisconsin, 6 April 1967. F.5 F.6 The title of the lecture was ‘Penicillins and Cephalosporins — their chemistry in relation to biological activity’. Correspondencere arrangements for Abraham’s visit to the USA and for his lecture University of Wisconsin, December 1966-March 1967; programme for Rennebohm Lectures. at the 39pp copy of typescript of lecture, with corrections and additions, and 1p manuscriptfigures. F.7, F.8 ‘Penicillins and Cephalosporins’ symposium, Las Vegas, 9-14 April 1967. The title of Abraham’s lecture was ‘Penicillins and Cephalosporins — their chemistry in relation to biological properties’. F.7 F.8 F.9 F.10 Correspondenceetc re invitation and arrangements, December 1965-March 1967. 3pp typescript draft, with manuscript corrections, of abstract of Abraham’s lecture. Correspondencearising from the two lectures and from thevisit to the USA in general, November 1966-September 1967. F.2-F.6, Miscellaneous material found with the papers described the USA visit: correspondence, mostly with apparently unrelated organisations in the USA, August 1966-April 1967; 2pp manuscript notes probablyfor a lecture (or lectures), one page entitled ‘Chicago’. to in E.P. Abraham NCUACS 103/2/02 123 Visits and conferences F.11-F.15 5th International Congress of Chemotherapy, Vienna, 26 June-1 July 1967. Abraham delivered a lecture ‘Synthesis and Semisynthesis of Some Antibiotics’. F.11 Correspondence re arrangements, with conference programme, October 1966-June 1967. F.12, F.13 Correspondencearising, May 1967-April 1968. 2 folders. F.14 F.15 16pp manuscript draft of lecture, with corrections; 13pp corrected typescript version with manuscript annotations. to, the drafts Manuscript notes and typescript lists of ‘technical terms’, found with, and probably relating Fifth Interscience Conference on Antimicrobial Agents and Chemotherapy and IVth International Congress of Chemotherapy, 1965, attended by Abraham; programme and other printed material, annotated by Abraham, from the Sixth Interscience Conference on Antimicrobial Agents and Chemotherapy 1966 which he doesnot appear to have attended. F.14; programme from the in This material was found with the papers in F.11-F.14. F.16-F.21 Visit to the USA, October 1967. Abraham delivered lectures at the annual meeting of the Infectious Diseases Society of America and at the Seventh on Antimicrobial Agents and Chemotherapy, both in Chicago. Interscience Conference F.16-F.18 Annual meeting of the Infectious Diseases Society of America, 23 and 24 October 1967. A provisional title for Abraham’s lecture is given as ‘Penicillinases and Cephalosporinases’ in the preliminary programme atF.16. F.16 Correspondence etc re arrangements for the USA trip and for Abraham's participation at the meeting, with preliminary programme, May-October 1967. E.P. Abraham NCUACS 103/2/02 124 Visits and conferences Correspondencearising, November 1967-January 1968. 19pp typescript corrections and revisions. draft of lecture, headed ‘Chicago’, with manuscript Seventh Chemotherapy, Chicago, 25-27 October 1967. Interscience Conference on Antimicrobial Agents and Abraham, with Guy Newton and S. Kuwabara, lectured on ‘Preliminary observations of “Cephalosporoic acids” and their derivatives’. spontaneous’ breakdown formation and on the Correspondencere arrangements, with programme etc, May 1967. Correspondencearising, 1967. Includedis a letter, 1969, found with the material relating to this conference. Printed booklet of abstracts of the papers presented at the conference. F.17 F.18 F.19-F.21 F.19 F.20 F.21 F.22-F.25 Gregynog Natural Products Symposia, 1969-1975. The purposeof the symposia, held in Gregynog Hall, Wales, wasto facilitate communication between research workers in industry and academic In 1971 the event was re-named ‘European Symposium on Bio- institutions. Organic Chemistry’. Abraham participated in the 1973 and 1975 symposia. The papers described in these folders were the contents of an original file inscribed ‘Gregynog’. F.22, F.23 Invitation to the 1970 Gregynog Symposium. Abraham agreedto participate in the event and partly prepared a lecture, but found he was unable to attend due to a mix-up in his diary. F.22 Correspondence re arrangements etc, with preliminary programme, July 1969-April 1970. Included are a re-print of a paper co-authored by Abraham and a typescript bibliography, found with the correspondence in this folder. E.P. Abraham NCUACS 103/2/02 125 Visits and conferences F.23 ‘Biosynthesis of Some Peptide Antibiotics’. 35pp typescript draft manuscript corrections, and accompanying figures, tables etc. of Abraham’s intended lecture so entitled, with F.24 European on_ Chemistry’, 18-21 May 1973. Symposium Bio-Organic Chemistry: ‘Microbiological Abraham delivered a lecture on ‘Aspects of the Biosynthesis of Penicillin and Cephalosporin’. Correspondence re arrangements, with programme etc, October 1972-April 1973. F.25 European Symposium on Biotransformation’, 16-19 May 1975. Bio-Organic Chemistry: ‘Biosynthesis and Abraham chaired one of the lecture sessions. Correspondence re arrangements and arising, December 1974-June 1975. with programme etc, F.26-F.31 8th [Italian] National Congress of Chemotherapyheld by the SocietaItaliana di Chemioterapia (Italian Society of Chemotherapy), Sardinia, 8-[?9 or 10] May 1970. Abraham was invited cephalosporins. to give the opening lecture in a session on F.26 F.27 Correspondence re arrangements, with programme, December 1969-April 1970. Correspondencearising, May-July 1970. F.28-F.31 ‘Reflections on the Development of the Cephalosporins’, Abraham’s lecture, published (after editing) in Giornale Italiano di Chemioterapia. F.28 F.29 12pp typescript draft, with corrections and revisions; copy of typescript of the lecture in Italian. 19pp typescript of the lecture with manuscript editing (for publication). E.P. Abraham NCUACS 103/2/02 126 Visits and conferences F.30 F.314 F.32 Copyof typescript of edited version with related photographs of chemical structures; copy of enclosing letter by Abraham, May 1970. Copyof galley proof with enclosing letter to Abraham, 1971. Symposium onAntibiotics, Quebec, Canada, 1-3 March 1971. Organised by The Medicinal Chemistry Division of the Chemical Institute of Canada. Programme Cephalosporins’. listing Abraham as a_ lecturer on ‘Penicillins and See H.351, H.352 for further papers concerning the symposium. F.33-F.36 FEBS Special Meeting on Industrial Aspects of Biochemistry, Dublin, 15-19 April 1973. Abraham delivered a lecture at the symposium on ‘Biological Syntheses’. F.33 Correspondence re arrangements and arising, with programme etc, August 1972-July 1973. F.34-F.36 ‘Studies on the Biosynthesis of Penicillins and Cephalosporins’. Abraham’s lecture, subsequently published in a ‘volume’ on the Symposium. F.34 F.35 F.36 2pp copy of typescript abstract of lecture with copy of enclosing letter by Abraham, January 1973; published volume of abstracts of lectures given at the conference. 11pp incomplete typescript draft of lecture, with manuscript corrections; draft figures (for ?slides) and manuscriptbibliography. 20pp typescript draft, with manuscript corrections and revisions, entitled ‘Penicillins, Cephalosporins and the Biosynthesis of Peptide Antibiotics by Fungi’, by Abraham andPatricia Fawcett. This appears to be a draft of the published version of the lecture with which Abraham required the help of a colleague due to lackof time. E.P. Abraham NCUACS 103/2/02 127 Visits and conferences F.37 Penicillinase Workshop, University of Newcastle upon Tyne, 16-18 April 1975. Abraham introduced and chaired a panel discussion. Correspondencere arrangements, with programme, March 1975. On the back of one letter (12 March) are rough manuscript notes by Abraham relating to topics and other speakers. F.38-F.41 5th FEMS Symposium, Basel, Switzerland, 14-16 September 1977. Abraham gave a lecture on ‘Developments Biochemistry of Beta-lactam Antibiotics’. in the Chemistry and F.38, F.39 Correspondence re arrangements and arising, February-August 1977. with programme etc, 2 folders. F.40 F.41 F.42 28pp copy of typescript of Abraham’s lecture with manuscript corrections and revisions; copies of bibliography and figures (for ?slides). The lecture was published in a book (Antibiotics and Other Secondary Metabolites) containing the contributions made at the symposium. Correspondence re manuscript notes and copiesof figures (for ?slides). March-May 1978. publication corrected proof, 2pp of lecture with ‘Future Prospects and Past Problems in Antimicrobial Therapy: the Role of Cefoxitin’, Harvard Club of Boston, USA, 24 and 25 May 1978. Programme listing Abraham as aninvited speaker. See H.465for further papers re this conference. F.43, F.44 Table Rondes Roussel Uclaf: ‘Mode of Action of Beta-Lactams’, Paris, 6 and 7 December 1979. Organised by the Roussel Uclaf Group. moderator. Abraham participated as a E.P. Abraham NCUACS 103/2/02 128 Visits and conferences F.43 F.44 Correspondence re arrangements, with list of participants etc, December 1978-November 1979. Correspondencewith individuals at Division Scientifique Roussel Uclaf and Roussel Laboratories re various matters, one letter arising from the above conference, October 1979-July 1980. Found with the material in F.43. F.45-F.51 International Symposium on B-lactam Antibiotics: ‘Mode of Action, New Developments and Future Prospects’, New York University Post-Graduate Medical School, 29 September-2 October 1980. ‘Launching the Antibiotic Era: Personal Accounts of the Discovery and Use of the First Antibiotics’, a symposium held at the Rockefeller University, New York, on 23 October 1989. The papers relating to these two symposia wereoriginally the contents of a file inscribed ‘Rockerfeller University / New York’. F.45-F.47 International Symposium on B-lactam Antibiotics, 1980. Abraham gave a lecture entitled ‘Discovery, Chemistry and Antibacterial Properties of Cephalosporins’. Correspondence September 1980. re arrangements, with programme etc, February- 1p manuscript notes for lecture; 13pp typescript of lecture with manuscript revisions (probably for publication). 15pp copyof typescript of ?published version of lecture. F.45 F.46 F.47 F.48-F.51 Symposium ‘Launching the Antibiotic Era’, 1989. The symposium washeld to celebrate the 50th anniversary of the discovery of Gramicidin by René Dubos. Abraham gave lecture entitled ‘Oxford, Howard Florey and World WarIl’. Abraham’s lecture and the contributions by other speakers appeared in a subsequent Rockefeller University Press publication Launching the Antibiotic Era, New York 1990. E.P. Abraham NCUACS 103/2/02 129 Visits and conferences F.48 F.49 F.50 F.51 Correspondencere arrangements, with programme, March-October 1989. 1p manuscript notes for lecture; 12pp typescript draft of lecture with manuscript corrections; 15pp typescript of expanded version; off-print of the publishedlecture. Correspondence, mostly re publication, 1989-January 1991. Rockefeller Copy of about the symposium and some of the participants (including Abraham); copies of printed literature providing general background to the symposium. University Newsletter including note F.52, F.53 21st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, USA, 4-6 November 1981. F.52 F.53 The subject of the conference was biosynthesis of B-lactam antibiotics. Abraham gave a lecture probably entitled ‘Enzymes Involved in the Biosynthesis of Cephalosporin C’. Correspondence etc re arrangements and arising, April-October 1981. 7pp typescript of lecture, with manuscript corrections, entitled as above and inscribed ‘Written from memory after the Chicago meeting’ on front page; 8pp typescript of the same with extensive manuscript revisions (probably for publication), the original title being altered to ‘An Outline Biosynthesis of Beta-Lactam Antibiotics’. F.53A First ASEAN Workshop on ‘Fermentation Technology applied to the utilization of food waste materials’, Kuala Lumpur 22-24 February 1982. 6pp typescript copies of 2 lectures given by Abraham entitled “B-lactam Antibiotics — an Outline’ and ‘Biosynthesis of B-lactam Antibiotics — an Outline’. See H.424-H.426for related material. E.P. Abraham NCUACS 103/2/02 130 Visits and conferences F.54-F.57 International Congress of Chemotherapy, Vienna, 28 August-2 13th September 1983. F.54 F.55 F.56 F.57 At the conference Abraham was presented with the Hamao Umezawa Award for Chemotherapy by the International Society of Chemotherapy and gave an Award Lecture entitled ‘Aspects of the Biosynthesis of Beta-Lactam Antibiotics’. Correspondence re arrangements, February-August 1983. 6pp copy of typescript of Award Lecture, with brief manuscript annotations, and a few manuscript and typescript possibly related; 14pp manuscript draft, with revisions, of unidentified lecture (on the biosynthesis of B-lactam antibiotics) headed‘Vienna’. notes, Copies of 2 printed ‘Proceedings’ of sections of the conference, one co- edited by Abraham; printed newsbulletin on the congress. Correspondence with individuals in Austria and West Germany re various matters, mostly unconnected with the congress 1982-1985. Found with the material in F.54-F.56. F.58, F.59 Meeting organised by E.R. Squibb & SonsInc.: ‘Therapeutics for a Changing World’, Princeton University, 27 September 1983. Held to commemorate the 125th Anniversary of the founding of E.R. Squibb & Sons Inc. F.58 F.59 Correspondencere arrangements, July-September 1983. 9pp untitled manuscript draft of lecture with revisions; first page of another manuscript draft of the same; 1p manuscript notes and 5pp annotated typescript information for lecture. F.60, F.614 607th Meeting of the Biochemical Society, Polytechnic of Central London, 19-21 December 1983. Abraham gavea lecture at a colloquium on ‘Advancesin the Biochemistry and Genetics of Antibiotic Producing Organisms’. E.P. Abraham NCUACS 103/2/02 131 Visits and conferences F.60 F.61 Correspondence re arrangements, with typescript summary of Abraham’s lecture and provisional programme, November 1982-November 1983. 1p manuscript notes for the lecture; correspondence re publication, June- September 1984; 8pp copy of typescript published version of the lecture entitled ‘Aspects of the Biosynthesis of Beta-Lactam Antibiotics’, with bibliography and figuresfor slides. F.62-F.67 Visit to India, January 1985. The principal reason for Abraham’s visit was to participate in the Asian Congress of Pharmacology, New Delhi, 14-19 January 1985. After the congresshevisited the Indian Institute of Technology, Ciba Geigy Research Centre, and the Tata Institute of Fundamental Research (Bombay), Hindustan Antibiotics Ltd and the National Chemical Laboratory (Poona), the Indian of Sciences (Bangalore), and the Central Food and Technology ResearchInstitute (Mysore). He gavea total of five seminars. Institute A photograph taken during this visit is at J.24. F.62, F.63 Correspondence re arrangements, with itineraries January 1985. etc, February 1984- 2 folders. F.64 Correspondenceetc arising, February-March 1985. F.65-F.67 ‘Penicillins and Cephalosporins and Antibiotics of the future’. Lecture given by Abraham at the Asian Congress of Pharmacology. F.65 F.66 F.67 21pp typescript draft of lecture, with corrections and revisions, and related tables and information. 23pp copy of revised version with copies of material for slides; 3 additional typescript pages, possibly part of the final text. Copy of printed abstract of the lecture, with possible manuscript draft of the same; 8pp manuscript notes and draft slides; manuscript notes found elsewhere, probably for this lecture (one page is headed ‘New Delhi’). E.P. Abraham NCUACS 103/2/02 132 Visits and conferences F.68-F.71 Hoechst Workshop Conference on ‘Regulation of Secondary Metabolite Formation’, Schloss Gracht, Germany, 12-16 May 1985. Abraham gavea lecture ‘Enzymes Involved in Penicillin and Cephalosporin Formation’. F.68 F.69 F.70 F.71 Correspondence re arrangements, with 2 annotated copies of programme, March 1984-May 1985. Correspondencearising; brief correspondence with German scientists re various matters. April-October 1985. 3pp incomplete manuscript draft of Abraham’s lecture with revisions; 14pp typescript of the lecture with additional pages of bibliographic references for possible publication. Typescript abstract of lecture with copy of earlier or expanded version; figures (for ?slides accompanying lecture). F.72-F.74 17th FEBS Meeting, WestBerlin, 24-29 August 1986. F.72 F.73 F.74 Abraham gavea lecture entitled ‘Beta lactamases’ at one of the Meeting’s symposia. Correspondence re arrangements and arising, November 1985-October 1986. 1p manuscript draft outline of lecture; 18pp copy of typescript of lecture, with manuscript corrections; additional typescript pages and figures (for ?slides). 1p typescript entitled ‘Abstract’; manuscript notes for lecture; miscellaneous papers, probably relating to the lecture, including re-print of earlier article by Abraham. E.P. Abraham NCUACS 103/2/02 F.75-F.81 Visits and conferences 133 50 Years of Penicillin Application’, a Symposium in Honour of Abraham organized 9-12 September 1990. Berlin, West Berlin, by the Technische Universitat Abraham gavea lecture entitled ‘From Penicillins to Cephalosporins’. See J.28 for photographstaken at the event. F.75, F.76 Correspondence re arrangements, with programme, and correspondence arising, October 1989-December 1990. 2 folders. F.77-F.81 Abraham’slecture: ‘From Penicillins to Cephalosporins’. The lecture was published in a book 50 Years of Penicillin Application — History and Trends (Technische Universitat Berlin). F.77 with 2pp manuscript and 1p typescript notes; 6pp and 2pp incomplete manuscript drafts manuscript corrections and 1p manuscriptlist of references; 11pp typescript final version (for publication). later 10pp typescript revisions; version with F.78 Figuresfor slides. F.79-F.81 Correspondence re publication corrected proofs, 1991-1994. with expanded typescript version and 3 folders. F.82, F.83 Penicillin Symposium, University of Oxford, 28 September 1990. The event was held to mark the 50th anniversary of the publication of the paper on penicillin in the Lancet which described animal experiments. Abraham gave a Beta-lactam descendants: chance, motivation and personalities’. F and its ‘Penicillin entitled lecture See J.40 for a videotape of this event, including Abraham’slecture. F.82 Correspondenceetc re arrangements, with 1 letter arising, January-October 1990. E.P. Abraham NCUACS 103/2/02 134 Visits and conferences F.83 1p typescript notes for Abraham’s lecture; 1p typescript entitled ‘Extract from the Will of Sir William Dunn’. F.84, F.85 Science and Medicine Conference, Royal College of Physicians, London, 6 and 7 November 1991. Abraham gave lecture entitled ‘Overview: past history of penicillins and cephalosporins’. F.84 F.85 Correspondence re arrangements, with programme, and correspondence arising, March-November 1991. 18pp typescript draft of lecture, with manuscript corrections and revisions, and drafts for accompanyingslides. F.86, F.87 ‘Phenoxymethylpenicillin amidohydrolase from penicillium chrysogenum’. Typescript drafts of a lecture so entitled, with manuscript revisions and corrections, [?1995]. Inscriptions on the drafts in F.86 indicate that the lecture was intended for a FEBS meeting. F.86 F.87 9pp draft manuscript corrections, inscribed ‘2nd Draft — reversibility - 6-APA?’. with manuscript revisions, inscribed draft with 1st Draft’; 3 further drafts one entitled ‘4th Draft Oct 1995’, with manuscript notes written to Abraham by another. F.88, F.89 Undated and unidentified visits. F.88 F.89 1 page of a manuscript draft of an unidentified lecture, n.d. Manuscript notes by Abraham for a lecture orlectures, n.d. One page is headed ‘New Delhi’, another ‘Biosynthesis’. E.P. Abraham NCUACS 103/2/02 135 SECTION G SOCIETIES AND ORGANISATIONS G.1-G.90 G.1-G.5 AMERICAN ACADEMY OF ARTS AND SCIENCES G.6-G.20 AUSTRALIAN NATIONAL UNIVERSITY G.21-G.28 BIOCHEMICAL SOCIETY G.27-G.29 BRITISH ASSOCIATION FOR THE ADVANCEMENTOF SCIENCE G.30-G.32 BRITISH COUNCIL G.33-G.39 BRITISH SOCIETY FOR ANTIMICROBIAL CHEMOTHERAPY G.40-G.44 CHEMICAL SOCIETY G.45-G.47 CIBA FOUNDATION G.48-G.57 COUNCIL FOR SCIENCE AND SOCIETY G.58-G.73 ROYAL SOCIETY G.74-G.78 ROYAL SOCIETY OF CHEMISTRY G.79-G.81 SOCIETY FOR GENERAL MICROBIOLOGY G.82-G.90 WELLCOME TRUST E.P. Abraham NCUACS 103/2/02 136 Societies and organisations G.1-G.5 AMERICAN ACADEMYOF ARTS AND SCIENCES 1983-1985 Abraham waselected a foreign honorary memberin 1983. In 1985 he gave an address to the Academy on ‘Penicillin and its successors: a personal view’. G.1-G.5 Correspondence and papers re honorary membership and address, 1983- 1985. Papers include manuscript notes and typescript drafts for address. 5 folders. G.6-G.20 AUSTRALIAN NATIONAL UNIVERSITY 1981-1988 In 1981 Abraham accepted an invitation to join a newly formed Advisory Board for the John Curtin School of Medical Research. He attendedits first meeting in Canberra, 24 September 1982 but does not appear to have attended subsequent meetings. Abraham’s correspondentis the Director of the John Curtin School, R. Porter. Correspondence, agenda, committee papers and minutes, 1981-1988. G.6 Correspondenceand papers, 1981. Includesinvitation for Abraham to serve on Advisory Board. G.7-G.9 Correspondenceand papers, 1982. Includes papers about the Advisory Board andits first meeting. 3 folders. Correspondence and papers, 1983. Includes papers for second meeting of Advisory Board, 5 August 1983. G.11 Correspondenceand papers, 1984. Includes papersfor third meeting of Advisory Board, 6 July 1984. E.P. Abraham NCUACS 103/2/02 137 Societies and organisations G.12-G.18 Correspondenceand papers, 1985. Includes papersfor fourth meeting of Advisory Board, 29 May 1985 andfifth meeting of Advisory Board, 25 September 1985. 7 folders. Correspondence and papers, 1986. Correspondenceand papers, 1987-1988. G.19 G.20 G.21-G.26 BIOCHEMICAL SOCIETY 1981-1997 G.21 Miscellaneous correspondence and papers,1981, 1984, 1989, 1992, 1997. G.22-G.26 Correspondence and papers re Abraham’s participation in the Society's programme of video recordings and related matters, 1989-1993. 5 folders. Abraham was recorded in conversation with Professor Robert Thomasat Imperial College London on 1 May 1990. The interview wasarranged by the Society's Honorary Archivist, Professor H.F. Bradford (see J.41 for a videotape of the interview). G.27-G.29 BRITISH ASSOCIATION FOR THE ADVANCEMENTOF SCIENCE 1980, 1986-1988 G.27, G.28 Correspondence and papers re Abraham’s 53rd Royal Society BAYS[British Association Youth Section] Lecture, 1980. Abraham delivered the lecture on ‘Penicillin and after’ at Gravesend School for Boys, Kent, 23 October 1980. 2 folders. E.P. Abraham NCUACS 103/2/02 138 Societies and organisations G.29 Correspondence and papers re the 1988 British Association for the Advancementof Science Annual Meeting at Oxford, 1986-1988. G.30-G.32 BRITISH COUNCIL 1960-1975 Correspondence and papers re Abraham’s involvement in British Council activities. G.30 G.31 1960, 1963. 1964. Includes papers re course on the use and abuseofantibiotics. G.32 1965, 1970, 1975. G.33-G.39 BRITISH SOCIETY FOR ANTIMICROBIAL CHEMISTRY 1972-1996 The Society was formed in August 1971 at the VIlth International Congress of Chemotherapy in Prague. Abraham was invited to join the Society in 1972 and became an honorary member in 1979. In 1974 he accepted an invitation to join the Editorial Board of the Society’s new journal Antimicrobial Chemotherapy. Abraham delivered the 5th L.P. Garrod Lecture to the Society on ‘B-Lactam Antibiotics: motivation, science and luck in their past and future’, 21 November 1986. Correspondence and papers. G.33 G.34 1972, 1974, 1979. 1984-1986. Includes typescript draft of Abraham’s L.P. Garrod Lecture. G.35 1991. E.P. Abraham NCUACS 103/2/02 139 Societies and organisations G.36 G.37 G.38 G.39 1992. 1993-1994. 1995. 1996. G.40-G.44 CHEMICAL SOCIETY 1965-1979 G.40-G.43 Correspondence and papers re publications, meetings, protein group etc., 1965-1979. G.40 G.41 G.42 G.43 G.44 1965-1968. 1969-1970. 1971-1973. 1975-1979. Papers re symposium on ‘Recent advancesin the chemistry of B-lactam antibiotics’, Cambridge, 28-30 June 1976. G.45-G.47 THE CIBA FOUNDATION 1957-1979 G.45 Correspondence and papers re symposium on amino-acids and peptides held in March 1958, 1957-1958. E.P. Abraham NCUACS 103/2/02 140 Societies and organisations G.46 Correspondence and papers re study group onresistance of bacteria to the penicillins, 1961-1962. G.47 Miscellaneous correspondence, 1973-1979. G.48-G.57 COUNCIL FOR SCIENCE AND SOCIETY 1985-1986 The Council for Science and Society was founded in 1973 and published a number of reports on various social issues connected with science and technology. Abraham accepted an invitation in 1985 to join a study group on accessto scientific information. G.48-G.57 Correspondenceand papers re the work of the study group. 10 folders. G.58-G.73 THE ROYAL SOCIETY 1958-1998 Abraham waselected to the Fellowship of the Royal Society in 1958 (Royal Medal, 1973; Mullard Medal, 1980). G.58-G.67 General correspondence and papers, 1958-1998. G.58 G.59 G.60 G.61 G.62 1958-1961. 1962-1963. 1964-1968. 1970-1972. 1973-1976. E.P. Abraham NCUACS 103/2/02 141 Societies and organisations G.63 G.64 G.65 G.66 G.67 1977-1978. 1979-1982. 1983-1989. 1990-1994. 1995-1998. G.68, G.69 Correspondence, papers and photographs re antibiotics exhibit for Royal Society Tercentenary exhibition, 1960. 2 folders. G.70-G.73 Correspondence and papersre elections, 1959-1995. G.70 G.71 G.72 G.73 1959-1968. 1971-1979. 1985-1989. 1990-1995. G.74-G.78 ROYAL SOCIETY OF CHEMISTRY 1985-1995 G.74 General correspondence and papers, 1985-1995. E.P. Abraham NCUACS 103/2/02 142 Societies and organisations G.75-G.77 Correspondence and papers re Centenary Tribute to Sir Robert Robinsonat the 1986 Annual Congress, 1985-1987, Abraham talked on ‘Sir Robert Robinson andthe early history of penicillin’. 3 folders. G.78 Correspondenceand papersre article on ‘The biosynthesis of penicillins and cephalosporins’ written with J.E. Baldwin, 1985-1988. G.79-G.81 SOCIETY FOR GENERAL MICROBIOLOGY 1963-1997 G.79 G.80 G.81 Abraham became a member in 1948 and resigned from the Society in 1997. Correspondence and papers re meeting etc, 1963. Correspondence and papersre publications, 1973, 1975. Correspondence and papers re publications, meetings and membership, 1981-1997. G.82-G.90 WELLCOME TRUST 1957-1989 G.82-G.87 Correspondence and papers re Abraham’s applications to the Wellcome Trust for grants for equipment, travel and to modernise / extend the chemical pathology section of the Oxford Departmentof Pathology, 1957-1965. 6 folders. G.88 Correspondence, 1979, 1981. E.P. Abraham NCUACS 103/2/02 143 Societies and organisations G.89, G.90 Correspondencewith historians at the WellcomeInstitute for the History of Medicine, London, 1985-1989. 2 folders. E.P. Abraham NCUACS 103/2/02 144 SECTION H CORRESPONDENCE H.1-H.563 H.1-H.334 SCIENTIFIC CORRESPONDENCE (presented alphabetically by individual) H.335-H.495 SCIENTIFIC CORRESPONDENCE (presented alphabetically by country) H.496-H.534 SHORTER SCIENTIFIC CORRESPONDENCE (chronological sequence) H.535-H.563 REFERENCES AND RECOMMENDATIONS E.P. Abraham NCUACS 103/2/02 145 Correspondence H.1-H.334 SCIENTIFIC CORRESPONDENCE (presented alphabetically by individual) 1944-1998 This sequence includes a large number of the scientists who researchedin Abraham's laboratory including D.Phil. students, post-doctoral fellows and visiting scientists. H.14 Baker, W.L. 1976 Baker was based at the Swinburne College of Technology, Hawthorn, Melbourne, Australia. Correspondence re possibility of work on penicillin problems in Abraham's laboratory during sabbatical leave. H.2-H.11 Baldwin, G.S. 1974-1992 Baldwin came to Abraham’s laboratory from the University of Melbourne in 1975 to work for two years as a postdoctoral researcher on the mechanism of enzyme function. He was subsequently based at the University of Adelaide and the Ludwig Institute for Cancer Research, Melbourne Tumour Biology Unit, Australia. H.2-H.6 Correspondence and papers re career and appointments, 1974-1992. Includes references and recommendations. H.2 H.3 H.4 H.5 H.6 1974. 1975. 1976-1978. 1980, 1983. 1991-1992. H.7-H.14 Correspondence and papersre research and publications, 1975-1990. E.P. Abraham NCUACS 103/2/02 146 Correspondence H.7 1975-1976. Includes correspondence and report re work of M. Tully on the production of B-lactamase| andIl, 1976. H.8 H.9 1976-1977 and n.d. Includes manuscript drafts by Baldwin. 1978. Includes correspondence with Biology, University of Edinburgh. R.P. Ambler, Department of Molecular 1979. 1979-1981, 1985, 1990. H.12-H.19 Berks, M. (née McPhail) 1971-1996 Berks worked in Abraham’s laboratory, 1971-1977, first as a research assistant and then as a post-doctoral researcher. She died in 1996. Career, research, publications and personal news. Includes references and recommendations. 8 folders. H.20 Betina, V. 1964-1972 University, Betina was based at the Department of Microbiology and Biochemistry, Slovak Polytechnic He met Abraham at the ‘Antibiotica Congressus’ in Prague, 1964 and subsequently worked in Abraham’s Laboratory for a period in 1966 on the antibiotic activity of cyanein supported by a World Health Organization Senior Research Training Grant. Bratislava, Czechoslovakia. Arrangementsfor visit, publication etc. E.P. Abraham NCUACS 103/2/02 Correspondence H.21 Blackwell, C.M. 147 1977 Blackwell was appointed to a two-year postdoctoral post in Abraham’s laboratory in 1977. Appointmentonly. Includes recommendations. H.22-H.29 Bleaney, R.C. 1974-1978 Bleaney was a postdoctoral organic chemist appointed to research in Abraham's laboratory on the synthesis of compounds related to penicillins and cephalosporins. H.22 Correspondence and papers re career and appointments, 1974-1978. Includes references and recommendations. H.23-H.29 Correspondence and papers re research, 1976-1978, n.d. 7 folders. H.30 Brannan, S. 1977 Brannan was appointed to a two-year postdoctoral post in Abraham's laboratory, 1977. Appointmentonly. Includes references and recommendations. H.31-H.37 Brightwell, M. 1972-1975 Brightwell came to Abraham’s laboratory as a research assistant in 1972 to work on the structure and function of members of the penicillinase group of enzymes. H.31, H.32 Correspondence and papersre career and appointments, 1972-1975. Includes recommendations. 2 folders. E.P. Abraham NCUACS 103/2/02 148 Correspondence H.33-H.37 Research notes, drafts and data, 1973-1975, n.d. 5 folders. H.38-H.42 Brétzu, G. 1971-1981 Italy. He of Brotzu was Director of the Institute of Hygiene, University of Cagliari, Sardinia, the cephalosporium organism in 1945 and provided it for further study to H.W. Florey and Abraham and their colleagues at Oxford University and the Medical Research Council in England which resulted in the developmentof the cephalosporin antibiotics. He died in 1976. discovered properties the antibiotic H.38 H.39 H.40 H.41 H.42 H.43 For related correspondence see C.1038-C.1041. Correspondence and papers re award of an honorary degree to Brétzu by Oxford University, 1971. Correspondence and papers re reception and dinner given in Brétzu’s honour by the National Development Research Council, 1972. Miscellaneous correspondence re Brétzu’s death, history of antibiotics etc, 1976-1981. Duplicated papers by Brétzu including ‘Ricerche su di un nuovo antibiotico’, Lavori dell'lstituto d’lgiene di Cagliari, 1948. Photographs. Browne, C.A. 1970-1976 Browne wasa D.Phil. student in the Sir William Dunn School of Pathology. Recommendations. H.44 Brownlee, G.G. 1979-1980, 1987 In 1980 Brownlee came from the MRC Molecular Biology Laboratory, Cambridge to take up the post of E.P. Abraham Professor of Chemical Pathology at the Sir William Dunn School of Pathology, Oxford. E.P. Abraham NCUACS 103/2/02 149 Correspondence H.45-H.49 Chaudhury, R.R. 1971-1993, 1998 Chaudhury was an Indian scientist who was a graduate student of Lincoln College, Oxford, 1955-1958. He pursued his career with the World Health Organisation (WHO) with a period at the Postgraduate Institute of Medical Education and Research, Chandigarh, India. Chaudhury visited Oxford for a WHO seminar in October 1971 when he renewed his acquaintance with Abraham. Career,visits etc. 5 folders. See also H.381. H.50-H.52 Chmara, H. 1978-1984, 1989 Chmara came from the Department of Pharmacology Technology and Biochemistry of the Technical University, Gdansk, Poland to workfor a year, 1978-1979, in Abraham’s laboratory on the antibiotic bacilysin. Correspondence and papers re arrangementsfor visit, research, publication, conference, etc. The correspondence is initiated by Chmara’s head of department in Gdansk, E. Borowski. 3 folders. H.53, H.54 Coombe, R.G. 1971-1977 Coombe came from the Pharmacy Department, University of Sydney to spend a sabbatical year from December 1971 in Abraham’s laboratory. Correspondence and papers re arrangementsfor visit, research etc. Includes research reports. 2 folders. H.55-H.66 Cornelis, G. 1973-1978 Cornelis came from Université Catholique de Louvain, Belgium to work in Abraham’s Laboratory for a few months in 1974. Correspondence and papersrevisit, research and publications. 12 folders. E.P. Abraham NCUACS 103/2/02 150 Correspondence H.67 Crawford, K. 1958, 1959, n.d. Crawford was a Departmental Demonstrator in the Oxford Department, commencing 1 December 1954. Includes report on ‘The enzymesinactivating Cephalosporins P and N and Penicillin’. H.68-H.73 Crout, D.H.G. 1979-1984 Crout was based at the Department of Chemistry, Exeter University. Correspondence and papers re research and publications. 6 folders. H.74-H.78 Davies, R.B. 1969-1974 Davies was a D.Phil. student of Abraham’s from October 1970. H.74 Correspondence and papers re career, 1969-1974. Includes references and recommenaations. H.75-H.78 Correspondence and papers re research and publications, 1971-1974 4 folders. H.79 Dougall, D.K. 1953-1956 Principally research reports. H.80 Duncan, M.J. 1965-1971 Duncan wasa D.Phil. student in the Sir William Dunn School of Pathology, Includes references and recommendations. E.P. Abraham NCUACS 103/2/02 151 Correspondence H.81 Dyke, K.D.G. 1966-1967 Correspondence and papers re research and career. Includes references and recommendations. H.82-H.84 Edwards, G.F. St L. 1974-1979 Edwards worked in Abraham’s laboratory as a post-doctoral research assistant, 1974-1977. H.82 Correspondence and papers re career and publication. Includes references and recommendations. H.83, H.84 Research notes and reports. 2 folders. H.85-H.91 Fawcett, P.A. 1971-1997 After graduating from the School of Biological Sciences, University of East Anglia, Fawcett came to Oxford to work as a research assistant in Abraham’s laboratory, taking a D.Phil. under his supervision. After a period in the USA she returned to England in 1979 and resumed research in Abraham’s laboratory in 1983. Correspondence and papers from 1975 are under her married name of Whiteman. See also C.1075-C.1082. H.85 Correspondence re career, 1971-1975. Includes references and recommendations. H.86-H.91 Correspondence and papers re research, publications, etc., 1971-1997. 6 folders. H.92-H.97 Fisher, A.J. 1976-1980 Fisher undertook D.Phil research under Abraham’s supervision. E.P. Abraham NCUACS 103/2/02 152 Correspondence H.92-H.94 Correspondenceand papers re D.Phil. supervision, 1976-1980. 3 folders. H.95-H.97 84pp typescript draft on B-lactam antibiotics with extensive manuscript revision. 3 folders. H.98 Freeman, R.F. 1972-1973 Correspondence and papers re application to undertake D.Phil research in Abraham’s laboratory. Includes references and recommendations. H.99 Fukumura, T. 1975-1979 Fukumura came from Osaka City University, Japan to research on B- lactamase in Abraham's laboratory for a period in 1976. Correspondence re arrangements, etc. H.100 Fuller, K.W. 1970 Fuller was based at the Botany School, Oxford University. Includes paper on proposed course on industrial biology. H.101-H.107 Furth, A.J. 1971-1977 Furth was a post-doctoral researcher in Abraham’s laboratory from January 1971 working on the active site of B-lactamase enzymes. She subsequently took up a post with the Open University. H.101 Correspondence and papers re career and appointments, 1971-1976. Includes references and recommendations. H.102-H.107 Correspondence and papers re research, publications, etc., 1972-1977. 6 folders. E.P. Abraham NCUACS 103/2/02 153 Correspondence H.108 Ghuysen, J.-M. 1976-1977 Ghuysen wasbasedat the University of Liege, Belgium. Correspondencere research. H.109, H.110 Glynn, M.F. 1970-1973 Abraham took over Glynn’s D.Phil. supervision on the sudden death of his previous supervisor. Principally re Glynn’s Oxford D.Phil. thesis. 2 folders. H.111 Gore, P.J.M. 1975-1978 Gore worked as a research assistant in Abraham’s laboratory for a period from 1 February 1977 Correspondence re career and research. Includes references and recommendations. H.112-H.115 Gunetileke, K.G. 1967-1978 Sinhalese who came from Gunetileke was a of Biochemistry, University of Toronto to spend a year in Abraham's laboratory, 1968-1969, as a postdoctoral fellow before returning to Ceylon. In Oxford he worked on problems relating penicillins and cephalosporins. He died ca 1989. biosynthesis to the the Department of See also H.128. H.112, H.113 Correspondence re arrangements to work in Abraham’s laboratory, subsequent career etc., 1967-1978. Includes references and recommendations. 2 folders. H.114, H.115 Research notes, September 1968-July 1969. 2 folders. E.P. Abraham NCUACS 103/2/02 154 Correspondence H.116-H.118 Harris, H. 1962-1992 Harris was head of the Sir William Dunn School of Pathology, 1963-1994 and Regius Professor of Medicine, University of Oxford, 1979-1992. H.116 1962-1963. Includes correspondencere Harris’s move to Oxford in 1963. H.117 1972-1992. Includes typescripts ‘Thoughts on the Regius Professorship of Medicine’ and ‘Why scientists do animal experiments’. H.118 Curriculum vitae and bibliography. H.119-H.121 Heatley, N.G. 1948, 1962, 1983-1991 Heatley was a member of the team of scientists under H.W. Florey who produced in Oxford and tested and investigated He also contributed to some of the early work on cephalosporium cultures. penicillin. See J.48 for a videotape of lectures, including one by Heatley, to celebrate the 50th anniversary of the paper describing the therapeutic properties of penicillin. H.119 ‘The antibiotic from tulip’. Typescript and manuscript draft with manuscript comments by Abraham, 1948. H.120 1962, 1983-1991. Includes papers re the history of penicillin. H.121 Copy of Yours magazine, January 1991. Features Heatley on the cover ‘Honoured at 80 The bedpan boffin whose work saved thousandsin the war’. E.P. Abraham NCUACS 103/2/02 Correspondence H.122 Hopwood, D.A. 155 1982 Hopwood wasthe head of the Department of Genetics, John InnesInstitute, Norwich. Correspondencere research. H.123-H.125A Huddleston, J.A. (née Mitchell) 1974-1980 Huddleston worked as a research assistant in Abraham's laboratory from October 1974. See C.698-C.833 for laboratory notes by Huddleston. H.123 Correspondence re appointmentetc, 1974, 1980. H.124-H.125A Research notes and drafts. 3 folders. H.126-H.131 Jayatilake, G. S. 1978-1993 Jayatilake was a Sri Lankan organic chemist who came to Abraham’s laboratory in 1978 where he worked on the biosynthesis of penicillins and cephalosporins in cell-free systems. See C.251-C.268 for laboratory notes by Jayatilake. H.126-H.128 Correspondence and papers re career and appointments, 1978-1993. Principally references and recommendations. 3 folders. H.129-H.131 Research reports, printed material etc., 1979-1981, 1991. 3 folders. E.P. Abraham NCUACS 103/2/02 156 Correspondence H.132-H.134 Jeffery, J. 1959, 1970-1981 Jeffery was a graduate studentin the Sir William Dunn School of Pathology, 1958-1961, working on the chemistry and biochemistry of a member of the cephalosporin family. After a period with ICI (Pharmaceuticals Division), Alderley Park, Cheshire he moved to the University of Aberdeen. Correspondence and papers re career and appointments. Principally references and recommendations. 3 folders. H.135-H.139 Kasik, J.E. 1965-1986 In 1966 Kasik spent sabbatical leave from the Department of Medicine, University of Chicago researching in Abraham’s laboratory where he worked on the relationship between penicillinase production and the sensitivity of mycobacteria to He returned to the University of Chicago, subsequently moving to the University of lowa. penicillins and cephalosporins. Correspondence re research, publications etc 5 folders. H.140-H.148 Kenig, M.D.J. 1970-1976 Kenig came from the Beecham Research Laboratories, Brockham Park, Surrey, to undertake D.Phil. research on the peptide antibiotic bacilysin under Abraham's supervision. H.140, H.141 Correspondencere career and appointments, 1970-1974. Includes references and recommendations. 2 folders. H.142-H.148 Correspondence and papers re research and publications, 1971-1976. 7 folders. H.149 Khuon, E. von 1984 Correspondence re proposed television documentary about Sir Alexander Fleming. E.P. Abraham NCUACS 103/2/02 157 Correspondence H.150-H.153 Kiener, P.A. 1973-1990 Kiener was a D. Phil. student (supervisor S.G. Waley) in the Sir William Dunn School of Pathology where he later did postdoctoral work. He researched on the active sites of two enzymes triosphosphate isomerase and B-lactamase| from Bacillus cereus. Correspondence and papers re career and appointments. Chiefly references and recommendations. 4 folders. H.154-H.160 Kuwabara, S. 1964-1993 Kuwabara came to Abraham’s laboratory as a postdoctoral member of his research staff paid for by the Medical Research Council from 1 January 1966. He was already an experienced enzymologist after working in the Netherlands and at a number ofinstitutions in the USA. At Oxford he studied two extracellular B-lactamases (| and Il) produced by Bacillus cereus. He was subsequently based at the Institute of Medical Science of the University of Occupational & Environmental Health, Japan. University of Tokyo, and the School of Medicine, H.154, H.155 Correspondence re career and appointments, 1964-1970. Includes references and recommendations. 2 folders. H.156-H.160 Correspondence and papers re research, publications, etc, 1966-1978, 1985, 1993. 5 folders. H.161-H.165 Loder, P.B. 1956-1975, 1986 Loder was graduate assistant to G.G.F. Newton in the Sir William Dunn School of Pathology, 1957-1959 and research assistant to Abraham, 1965- 1966 and 1968-1972 working on cephalosporin and penicillin antibiotics. She moved from scientific research to administration in 1972 when she took a postat the head office of the Medical Research Council. See C.234, C.235 for laboratory notes by Loder. E.P. Abraham NCUACS 103/2/02 158 Correspondence H.161-H.163 Correspondence and papers re career and appointments, 1956-1975, 1986. Includes references and recommendations. 3 folders. H.164, H.165 Research notes and drafts. 2 folders. H.166-H.169 Luego, J.M. 1979-1985 Luego came from the University of Salamanca, Spain to work in Abraham’s laboratory as a postdoctoral fellow. H.166 Correspondence re arrangements to work in Abraham’s laboratory including fellowship application, 1979-1981. H.167 Research report. H.168, H.169 Correspondence and papers re publications, 1985. 2 folders. H.170 Marston, R.Q. 1973 Marston was Director of the National Maryland, 1968-1973 (Rhodes Scholar, Lincoln College, Oxford, 1947). Institutes of Health, Bethesda, Includes curriculum vitae and lists of addresses and publications. H.171-H.174 Migliacci, A. 1961-1963, 1969 Migliacci came from Farmitalia, Milan, Italy to work for a period in Abraham's laboratory. See also H.366. Also found with papers relating to Migliacci were papers relating to the work of ‘Mrs Jago’. Correspondence and papers re research, 1961-1963, 1969, most undated. 4 folders. E.P. Abraham NCUACS 103/2/02 159 Correspondence H.175-H.181 Miller, J.M.T. Hamilton- 1965-1981 Hamilton-Miller came to Abraham’s laboratory from Guy’s Hospital Medical School in January 1967 with a Junior Research Fellowship from the Medical Research Council, subsequently moving to the Charing Cross Hospital Medical School and the Royal Free Hospital School of Medicine, London. H.175-H.179 Correspondence and papers re move to Oxford, research, publications etc., 1965-1979. 5 folders. H.180, H.181 Correspondence and papers re career and appointments, 1967-1971, 1981. Includes references and recommendations. 2 folders. H.182-H.196 Newton, G.G.F. 1944-1997 Newton became a D.Phil. student in the Sir William Dunn School of Pathology in 1947 with Abraham as his supervisor. They continued to work together until his death in 1969. Much of the early work was concerned with antibiotic peptides such as bacitracin. Later Newton made substantial contributions to the isolation of Penicillin N and Cephalosporin C and the determination of their structures. Some of the money from the development of the cephalosporins was diverted His name was also commemorated in the title of a Visiting Professorship at Oxford in the Medical, Biological and Chemical Sciences which Abraham set up. into a Guy Newton Research Fund. See C.228, C.308, C.1042-C.1048 and elsewhere in section C for papers and correspondencerelating to Newton’s work. H.182-H.189 Correspondenceand papersre career, research, publications, visits etc with Abraham and others, 1948-1968. Some of the letters from Abraham are undated and their assignment is tentative. H.182 1948-1955. Includes reports on work done, 1952-1953 and 1953-1954. E.P. Abraham NCUACS 103/2/02 160 Correspondence H.183 1956-1957. H.184 1958-1959. H.185 1960-1965. H.186 1966. Includes two copies of ‘G.G.F. Newton - Senior Research Officer Report on first period of office. Oct. - Sept. 1966’. H.187 1967. Includes ‘Report on visit to the USA by E.P. Abraham and G.G.F. Newton October-November 1967’. H.188 1968. H.189 Undated papers. Include ‘Comments by GFN on HSB[urton]’s Declaration’ and ‘Possible experiments to be considered for the new Honours School of Physiological Sciences Experiments in “Chemical Pathology”. 99 H.190 Letter from E.J. Farrar, Chief Chemist, to T.l. Williams at the Sir William Dunn School of Pathology, Oxford, 8 December 1944 with a ‘rough draft of the few experimental fermentations, using Aspergillus Fermagatus, Mut. Helvola which we have been able to set up sofar’. Found with Newton’s papers. H.191-H.194 Correspondence and obituaries, January-September 1969. papers arising from Newton’s death including H.191 January. E.P. Abraham NCUACS 103/2/02 161 Correspondence H.192 February. H.193 March. H.194 April - September. H.195 Correspondence about Newton or with or about members of his family, 1971-1997. H.196 Photographs. H.197-H.201 O'Sullivan, J. 1975-1994 Sullivan came from the Eidgendssiche Technische Hochschule, Zurich, to workin a postdoctoral position in Abraham’s laboratory, 1975-1979, on the biosynthesis of penicillins and cephalosporins. He subsequently madehis career at the Squibb Institute for Medical Research, Princeton, New Jersey, USA. H.197-H.199 Correspondence and papers re career and appointments, 1975-1992 Includes references and recommendations. 3 folders. H.200, H.201 Correspondence and papers re research, publications etc, 1977-1994. 2 folders. H.202-H.211 Pang C.-P. 1975-1996 Pang was born in Hong Kong andtooka first degree at Chelsea College, University of London, 1975-1978 before becoming a D. Phil. student at Oxford under Abraham’s supervision, 1978-1981. He was a postdoctoral research assistant in Abraham's laboratory, 1982-1983. His career was subsequently based at the Department of Chemical Pathology, Faculty of Medicine, Chinese University of Hong Kong. See C.284 for laboratory notes by Pang. E.P. Abraham NCUACS 103/2/02 162 Correspondence H.202, H.203 Correspondence and papers re career and appointments, 1978-1994. Includes references and recommendations. 2 folders. H.204-H.210 Correspondence and papers re research, publications, visits etc., 1978- 1996. 7 folders. H.211 Duplicated research notes, 1975-1978. Pre-date Pang’s arrival at Oxford but found with papers relating to his work. H.212 Park, J.T. 1970 Park was based at the Department of Microbiology, University of Umea, Sweden. Correspondencerevisit to Oxford, 1970. H.213-H.226 Perry, D. 1974-1989 Perry came from the University of Birmingham to work in a postdoctoral position in Abraham’s laboratory, 1974-1978, on the mechanism of action of the dipeptide antibiotic bacilysin. After a period at Princeton he returned to Abraham's laboratory in 1983 to work on isopenicillin N synthetase before moving to a lectureship at the Polytechnic of Central London. See C.1071-C.1074 for related material. H.213-H.215 Correspondence and papers re career and appointments, 1974-1986. Includes references and recommendations. 3 folders. H.216-H.221 Correspondence and papers re research and publications, 1974-1989. 6 folders. E.P. Abraham NCUACS 103/2/02 163 Correspondence H.222-H.226 Research notes and drafts, 1976, 1977, n.d. 5 folders. H.227 Richmond, M.H. 1970-1978 Richmond wasProfessor of Bacteriology, University of Bristol. Correspondencere research etc., 1970-1978. H.228-H.231 Robinson, R. 1971-1990 Correspondence re historical biography of Robinson etc. reflections, Robinson’s scientific memoirs, H.228 Correspondence with Robinson rehistory of penicillamine, etc, 1971-1975. The sequence includes Abraham’s correspondence with W. Baker on the same subject and a brief outline of the work on penicillin and cephalosporin with which Abraham was concerned between 1940 and 1961. H.229 H.230 Photocopies of Baker’s correspondence with Robinson on penicillamine, and ‘Some recollections of the early work on penicillamine’ by Baker, 1971. Correspondence re section of Robinson’s memoirs on penicillin sent to Abraham by Lady Robinson after his death ‘for help on checking the chemistry and putting in formulae’, 1975. Includes corrected typescript on ‘chemistry of penicillin’. H.231 Correspondence and papers, 1976, 1983-1990. Correspondence, 1983-1990, is re biography of Robinson byT.I. Williams. H.232-H.246 Sabath, L.D. 1962-1993 Sabath came from the Harvard Medical School, Boston, Massachusetts, to work in Abraham’s laboratory as a US Public Health Service Special Research Fellow, September 1963-September 1964, his support being renewed for a second year. He returned to the Harvard Medical School of subsequently moving to Medicine, Minnesota (Head of the Infectious Diseases Section) in 1974. /... the Department of University E.P. Abraham NCUACS 103/2/02 164 Correspondence fess In 1970 he accepted an invitation to become a Trustee of the E.P. Abraham Cephalosporin Fund. See C.233 for laboratory notes by Sabath. H.232-H.245 Correspondence re arrangements to come to Oxford, research, publications and visits, 1962-1993. H.232 1962. H.233 1963. H.234 1964. H.235, H.236 1965. 2 folders. H.237, H.238 1966 2 folders. H.239 1967-1970. H.240, H.241 1971. 2 folders. H.242 1972-1973. H.243 1974-1975. H.244 1976-1985. E.P. Abraham NCUACS 103/2/02 165 Correspondence H.245 1987-1993. H.246 Correspondence and papers re career and appointments, 1967,1972. H.247, H.248 Schaaf, C.H. 1971-1993 Schaaf was Resident Representative of the United Nations Development Programme in Ceylon when the correspondencewasinitiated. Principally non-scientific correspondence but includes a few references to Abraham's work. 2 folders. H.249-H.253 Stevens, C.M. 1972-1980 Stevens came from the Chemistry Department, Washington State University, Pullman to spend a sabbatical year in Abraham’s laboratory, 1973-1974. Correspondence and papers re arrangements for sabbatical, research, publications etc. 5 folders. H.254, H.255 Thorniley, M.S. 1984-1986 Thorniley was appointed as a research assistant in the Sir William Dunn School of Pathology from 1 October 1984. She worked ontheisolation and properties of isopenicillin N synthetase, an enzyme with a central role in the biosynthesis of penicillins and cephalosporins. See C.1083-C.1088for laboratory notes by Thorniley. H.254 H.255 Correspondence re appointmentetc., 1984-1985. Research notes and drafts, 1986 and n.d. E.P. Abraham NCUACS 103/2/02 166 Correspondence H.256-H.266 Umezawa,H. 1972-1986 Umezawa was Director of the Institute of Microbial Chemistry, Microbial Chemistry Research Foundation, Tokyo, Japan. He was the leading chemical microbiologist in Japan, distinguished for his discovery and study of compounds with by microorganisms, particularly by actinomycetes. He visited Oxford on a number of occasions, receiving an honorary degree from the University in 1981. He died in 1986. activity produced biological See also H.419. H.256-H.261 Correspondencerevisits to Oxford, honorary degree etc, 1972-1986. 6 folders. H.262-H.266 Obituary and miscellaneous biographical information. 5 folders. H.267, H.268 Umezawa, K. 1972-1986 Kazuo Umezawa wasthe son of H. Umezawa. In 1973 he came to Oxford to read medicine after obtaining a Ph.D. in Chemistry at the Massachusetts Institute of Technology (supervisor J.C. Sheehan). Correspondence and papers re move to Oxford in 1973 and subsequent visits. Includes references and recommendations. H.267 1972-1973. H.268 1976-1977, 1982-1983, 1986. H.269-H.281 Usher, J.J. 1970-1991 Usher undertook D.Phil research under Abraham’s supervision, 1970-1974, working on the role of certain peptides and antibiotics in the synthesis of penicillins and cephalosporins. H.269-H.276 Correspondence and papers re career, appointments and publications, 1970-1991. 8 folders. E.P. Abraham NCUACS 103/2/02 167 Correspondence H.277-H.281 Research notesand drafts. 5 folders. H.282-H.286 Vandamme, E.J.M.C. 1973-1994 Vandamme came from the University of Ghent, Belgium to work in Abraham’s laboratory during the summer of 1973 on the modeof a peptide antibiotic bacilysin which inhibits bacterial cell wall synthesis. Abraham was a member of the board of examiners for Vandamme’s D.Sc. thesis in 1976. H.282-H.285 Correspondence re arrangements for stay in Oxford, research, publications, D.Sc. thesis, etc., 1973-1977. 4 folders. H.286 Correspondencere career and appointments, 1985-1994. H.287, H.288 Vanderhaeghe, H. 1973-1987 Vanderhaeghe was based at the Rega Instituut, Katholieke Universiteit Leuven, Belgium and researched in the penicillin field. Abraham gave a lecture on ‘B-Lactam Antiobiotics: Science and Serendipity’ on the occasion of Vanderhaeghe’s retirement in 1987. H.287 Correspondencereresearch, visits, etc., 1973-1984. H.288 Correspondence re Abraham’s visit on the occasion of Vanderhaeghe’s retirement and draft of his lecture, 1987. H.289 Vlietinck, A.J. 1977 Vlietninck was based at the Pharmacy Department, Antwerp University. Correspondence re proposed research project on Levamisole, ‘a new drug with immunoregulatory properties’. E.P. Abraham NCUACS 103/2/02 168 Correspondence H.290-H.297 Waley, S.G. 1969-1994 Waley was Senior Research Officer, Nuffield Laboratory of Ophthalmology, Oxford, 1954-1970 and University Lecturer in Pathology, Sir William Dunn School of Pathology, Oxford, 1970-1989. He wasparticularly noted for his work on the mechanism by which enzymes exert their activity by converting one chemical substance to another. He died in 1993. H.290 Correspondence and papers re move to Sir William Dunn School of Pathology, 1969-1970. H.291-H.296 Research notes and drafts, 1973-1977, n.d. 6 folders. H.297 Correspondence and papers, 1989-1994. Includes obituary by Abraham, Independent, 1 January 1994. H.298-H.301 Walker, J.E. 1969-1976, 1988, 1995, 1997 Walker undertook D.Phil. research under Abraham’s supervision, 1966- 1969, working on the isolation, structure and biological properties of a peptide antibiotic. After a number of postdoctoral positions in the USA and Europe he became a staff at the MRC Molecular Biology Laboratory, Cambridge. He was awarded the 1997 Nobel Prize for Chemistry for work on the enzymatic mechanism underlying the synthesis of adenosinetriphosphate (ATP). scientist See C.237-C.240 for laboratory notes etc by Walker. H.298-H.300 Correspondence re research and publications, 1969-1973, 1988, 1995, 1997. H.298 1969-September 1970. Includes photographs. H.299 October-December 1970. E.P. Abraham NCUACS 103/2/02 169 Correspondence H.300 1971-1973, 1988, 1995, 1997. Walker's letter to Abraham of 10 August 1995 gave him ‘the opportunity to write to ... express my appreciation of the help and guidance that you gave me at a critical time in my scientific development’. H.301 Correspondence and papers re career and appointments, 1969-1976. H.302 Warren, S.G. 1966-1967, 1980 Warren wasbasedat the Sir William Dunn School of Pathology, 1962-1966, working in close association with G.G.F. Newton on the problem of the biosynthesis of antibiotics by certain fungi. Correspondencere research and career. ‘H.302 Includes recommendation. H.303-H.305 White, R.L. 1979-1989 White came from McMaster University, Ontario, Canada in November 1979 to work as a Postdoctoral Fellow in Abraham’s group on_penicillin- cephalosporin biosynthesis, returning to Canada in 1981. Correspondencere research, publications, career and appointments. H.303-H.305 Includes references and recommendations. 3 folders. H.306-H.334 Wylie, J.A.H. 1968-1987 Wylie was a microbiologist and experimental pathologist. He came to Oxford in 1945 as assistant bacteriologist in the Emergency Public Health Service, temporarily situated in the Sir William Dunn School of Pathology. After two years he became departmental demonstrator in the samebuilding. He washelped through difficult times in his later years by manyfriends and former colleagues including Abraham. Correspondence and papers. H.306 1968. E.P. Abraham NCUACS 103/2/02 Correspondence H.307, H.308 1969. 2 folders. H.309, H.310 1970. 2 folders. H.311, H.312 1971. 2 folders. H.313, H.314 1972. 2 folders. H.315 1973. H.316, H.317 1974. 2 folders. H.318, H.319 1975. 2 folders. H.320 1976. H.321, H.322 1977. 2 folders. H.323, H.324 1978. 2 folders. E.P. Abraham NCUACS 103/2/02 171 Correspondence H.325 1979. H.326 1980-1981. H.327, H.328 1982. 2 folders. H.329 1983-1984. H.330 1985-1987. H.331 H.332 Correspondence anddrafts re obituary of Wylie (published in The Lancet, 7 November 1987), 1987. Biographical information about Wylie including curriculum vitae and list of publications; photograph of Wylie. H.333, H.334 Copies of Wylie’s publications in the history of medicine and the history of religion. H.335-H.495 SCIENTIFIC CORRESPONDENCE (Presented alphabetically by country) H.335-H.342 Australia 1946-1995 1959-1995 H.335-H.340 IUPAC International Symposium on the Chemistry of Natural Products, Melbourne, Canberra and Sydney,Australia, 15-25 August 1960. See E.37, F.2 for related material. E.P. Abraham NCUACS 103/2/02 172 Correspondence H.335-H.338 Correspondence re arrangements for Abraham to give a paper at the symposium with associated visits and travel, 1959-1960. 4 folders. H.339 Abraham’s addresses, 3 August-1 October 1960; reprint of his symposium paper,etc. H.340 Correspondencearising from his visit to Australia, 1960-1961. H.341, H.342 Miscellaneous correspondencewith Australian scientists, 1961-1995. H.341 1961-1966. H.342 1968-1972, 1976-1978, 1988, 1995. H.343-H.349 Belgium 1969-1993 H.343-H.346 European Meeting on Medicinal Chemistry, Brussels, 14-17 September 1970. Abraham gave a plenary lecture on ‘Some contributions of synthesis and semisynthesis to antibacterial and antiviral chemotherapy’. H.343 Correspondence re arrangements for meeting, publication of plenary lecture etc., 1969-1971. H.344 Programme, list of participants, etc. H.345 Typescript draft of Abraham’s plenary lecture. H.346 Duplicated papers (? background materialfor lecture). E.P. Abraham NCUACS 103/2/02 173 Correspondence H.347 Miscellaneous correspondence with Belgian scientists, 1972, 1976, 1983, 1978, 1989. 1993. H.348, H.349 Correspondence and papers re the George Sarton Chair, University of Ghent, 1988-1991. 2 folders. Abraham was chosen for the George Sarton Chair for the academic year, 1989-1990. He gave his Sarton Chair lecture on ‘Reflections on the Developmentof the Penicillins and Cephalosporins’ A typescript draft of Abraham’s lecture is at H.349. H.350-H.353 Canada 1955-1985 H.350 Miscellaneous correspondence with Canadian scientists, 1955-1963. H.351, H.352 Correspondence and papers re Symposium on Antibiotics, Ste Marguerite, Quebec, 1-3 March 1971. Abraham gave a paper on ‘Penicillins and Cephalosporins’. 2 folders. A typescript draft of Abraham’s paper is at H.352. H.353 Miscellaneous correspondence with Canadian scientists, 1972-1973, 1981, 1985. H.354, H.355 China 1982-1987 H.354 H.355 Correspondence re review article by Abraham for the Chinese Journal of Antibiotics, with draft of article, 1982-1984. Correspondence re visit to Abraham’s department by Chinesescientist, 1986-1987. E.P. Abraham NCUACS103/2/02 174 Correspondence H.356-H.360 Czechoslovakia 1960-1974, 1986 H.356-H.358 Correspondence and papers re Antibiotics Congress held in Prague, June 1964, 1960, 1963-1965. 1960 research correspondence wasfound with the Congresspapers. 3 folders. H.359, H.360 Miscellaneous correspondence with Czechoslovak scientists, 1961-1974, 1986. 2 folders. H.361-H.363 Denmark 1971-1972, 1982-1991 H.361, H.362 Antibiotics Correspondence and Biosynthesis and Function held in Aarhus 28 August-2 September 1972, 1971-1972. re Euchem Conference on papers 2 folders. H.363 Miscellaneous correspondencewith Danish scientists, 1982-1991. H.364, H.365 Germany 1970-1994 Miscellaneous correspondence with Germanscientists. H.364 1970-1979. H.365 1985-1994. H.366-H.377 Italy 1961-1991 H.366 Correspondence re arrangements etc for A. Migliacci of Farmitalia to work for a period of six months in Abraham’s laboratory, 1961-1962. See also H.171-H.174. E.P. Abraham NCUACS 103/2/02 175 H.367 H.368 Correspondence Miscellaneous correspondence with Italian scientists, 1962-1965. Correspondence and the International Society of Clinical Pathology held in Rome October 1966, 1965-1966. Congress of International papers 6th re Abraham gave a paperon ‘Old and NewAntibiotics’ in a symposium on the evaluation of antibiotic activity. H.369 Miscellaneous correspondencewithItalian scientists and others, 1968-1971. In 1971 Abraham stayed for a short period at the Rockefeller Foundation’s Villa Serbelloni, Bellagio to write his memoir of Lord Florey for the Royal Society. H.370 Miscellaneous correspondencewith Italian scientists, 1973-1976. H.371 Correspondence and papersre scientific meetings held in Italy, 1978. Includes draft cerufoxime at Chemotherapy’ held in Pisa, May 1978. of Abraham’s introductory remarks for round table on in International Symposium on Trends ‘Future 3rd H.372, H.373 Correspondence and papers re symposium on ‘Action of Antibiotics in Patients’ held in Florence 18 July 1981 and publication of proceedings, 1980-1981. Abraham gave a paper on ‘Bioconversion of antibiotics’. The symposium was held just before the 12th International Congress of Chemotherapy, also held in Florence. 2 folders. H.374, H.375 Correspondence and papers re symposium ‘From Genetic Experimentation of Biotechnology the Critical Transition’ held in Rome, 20-23 September 1981, 1981. Abraham gave cephalosporins- similarities and contrasts’. paper on ‘The a development of penicillins and 2 folders. E.P. Abraham NCUACS 103/2/02 176 Correspondence H.376, H.377 Correspondence and papersre international meeting on ‘Trends in Microbial Resistance Molecular Aspects and Clinical Implications' held in L’Aquila and Rome, 12-15 May 1990. 1989-1991. to B-Lactam Antibiotics The meeting markedthefiftieth anniversary of the paper by Abraham and E.B. Chain (Nature, Dec. 28, 1940) in which the ability of some bacterial extracts to destroy penicillin was reported. Abraham gave a paper on ‘A retrospective view of B-lactamases’. See J.29 for a related photograph. H.378-H.381 ‘India and Pakistan’ 1961-1987 Contents of folder so inscribed: correspondence and papers re research, publications and visits. H.378 1961-1969. H.379 1970-1979. H.380 1980-1987. H.381 ‘Herbal Therapeutics’. 29pp typescript by R.R. Chaudhury,n.d. H.382-H.421 Japan 1953-1992 H.382 Correspondence with Japanesescientists, 1953-1954, 1961-1962. H.383-H.388 Correspondence and papers re IUPAC Symposium on ‘The Chemistry of Natural Products Kyoto, 12-18 April 1964, 1963-1964. 6 folders. E.P. Abraham NCUACS 103/2/02 177 Correspondence H.389 Correspondencewith Japanese scientists, 1965-1966. H.390 Correspondencewith Japanesescientists, 1967. Includes papers re the Journalof Antibiotics. H.391 H.392 Correspondence with Japanese scientists, 1968-1969. Correspondence with Japanesescientists and others, 1970-1971. H.393 Correspondence with Japanesescientists and others, 1972. Abraham had to cancela visit to Kyoto for the 4th International Fermentation Symposium, 19-25 March. H.394 Correspondence with Japanese scientists and others, 1973. H.395-H.400 Correspondence and papersre visit to Japan and the USA, 1974. Abraham attended the First Intersectional Congress of the International Association of Microbiological Societies in Tokyo in early September and then flew to San Francisco for the Fourteenth Interscience Conference on Antimicrobial Agents and Chemotherapy. 6 folders. H.401 Correspondencewith Japanese scientists, 1974-1977. H.402-H.408 Correspondence and papersrevisit to Japan in 1977, 1976-1977. Abraham attended a meeting to mark the 15th anniversary of the Microbial Chemistry Research Foundation Institute of Microbial Chemistry and the 30th anniversary of the Journalof Antibiotics, Tokyo, 25 and 26 October. He gave a lecture at the meeting on B-lactam Antibiotics and Related Substances. Abraham also visited other locations in Japan and India and Malaysia. 7 folders. E.P. Abraham NCUACS 103/2/02 178 Correspondence H.409 Correspondence with Japanese scientists, 1978. H.410, H.414 Correspondence with Japanese scientists, 1979. 2 folders. H.412 Correspondencewith Japanese scientists, 1980. Includes ‘A short history of the B-lactam antibiotics’, 17pp typescript by Abraham for a volume on B-lactam antibiotics. H.413 Correspondence with Japanesescientists, 1981. H.414 Correspondencewith Japanese scientists, 1982. H.415 Correspondencewith Japanesescientists, 1983 H.416 Correspondencewith Japanese scientists, 1984. Includes penicillins cephalosporins’, 12pp typescript + references andfigures by Abraham. discovery brief the of ‘A history of the and H.417 Correspondencewith Japanesescientists, 1985. Includes Abraham’s curriculum vitae after 1979. H.418 Correspondence with Japanese scientists, 1986 Includes Abraham’s curriculum vitae. H.419 Correspondencewith Japanese scientists, 1987-1988. Includes correspondence and papers re obituary and memorial symposium for H. Umezawa, Director of the Microbial Chemistry Research Foundation Institute of Microbial Chemistry and re Journalof Antibiotics. E.P. Abraham NCUACS 103/2/02 179 Correspondence H.420 Correspondencewith Japanesescientists, 1989-1990. Includes correspondenceand papers re Journal of Antibiotics. H.421 Correspondence with S. Yamabe, System Director of Drug Research System International, 1991-1992. H.422-H.429 ‘Malaysia’ 1976-1994 The sequence includes correspondencewith Singaporeanscientists. H.422 Correspondence with Malaysian scientists, 1976-1977. Includesinvitation from Royal Society for Abraham to consider Royal Society Inter-University Council Visiting Professorship at the University of Malaya, Kuala Lumpur. Abraham visited the Department of Genetics and Cellular Biology at the University for a few days in October 1977. H.423 Correspondence with Ho Coy Choke of the Department of Genetics and Cellular Biology, University of Malaya and others, 1980-1981. H.424-H.426 Correspondence and papers re First Asian Workshop on Fermentation Technology held in Kuala Lumpur, 22-24 February 1982, 1981-1982. Abraham spoke at the Kuala Lumpur meeting on ‘B-lactam Antibiotics’ and the ‘Biosynthesis of B-lactam Antibiotics’. He also visited Singapore and Sri Lanka. See also F.53A. 3 folders. H.427 H.428 Correspondencewith Malaysian and Singaporeanscientists, 1982-1985. Correspondencewith Malaysian and Singaporeanscientists, 1986-1988. E.P. Abraham NCUACS 103/2/02 180 Correspondence H.429 Correspondence with Ho Coy Choke, Department of Genetics and Cellular Biology, University of Malaya, 1989-1994. H.430-H.432 Spain 1970-1993 H.430 H.431 H.432 Correspondence re article on the chemistry of new antibiotics for Tribuna Medica, 1970-1971. Correspondence and papers re Third International Symposium on Yeast Protoplasts in Salamanca 2-5 October 1972, 1972. Correspondence with Spanish scientists re research and visits, 1978-1981, 1986, 1993. H.433-H.438 Sweden 1975-1992 H.433-H.437 Correspondence and papers re visit to Sweden in December 1975, 1975- 1976. Abraham wasinvited by the British Council to visit the University of Umea and by the Pharmacological Society of Swedento give its Scheele lecture. 5 folders. H.438 Correspondencewith Swedish scientists and others, 1976, 1984-1992. H.439-H.493 USA 1946-1993, n.d. H.439-H.464 General correspondence with American scientists and others, 1946-1991. H.439 1946-1949. H.440 1950-1951. E.P. Abraham NCUACS103/2/02 181 Correspondence H.441 1952 H.442 1953. H.443 1954. H.444 1955 January-June. H.445 1955 July-December. H.446 1956-1957. H.447 1958. H.448 1959. H.449 1960. H.450 1961. H.451 1962 January-April. Includes papers re 1962 Gordon Conference on Medicinal Chemistry. H.452 1962 May-December. Includes papers re 1962 Gordon Conference on Medicinal Chemistry. H.453 1963. E.P. Abraham NCUACS 103/2/02 182 Correspondence H.454 1964. H.455 1965-1966. H.456 1967. Includes short article on E.B. Chain written by Abraham for Encyclopedia Americana. H.457 1968. H.458 1969. H.459 1970. H.460 1971-1972. H.461 1973. Correspondence and papersre visit to the USA by Abraham in May. H.462 1975, 1978-1979. H.463 1980-1981, 1984-1988. H.464 1990-1991, n.d. H.465-H.469 Harvard University 1978-1993 Correspondence with colleagues at Harvard re visits, conferences,lectures, publications etc. E.P. Abraham NCUACS 103/2/02 183 Correspondence H.465 1978. Includes correspondence and papers re symposium on the cephalosporin derivative cefoxitin held at Harvard in May. Abraham gavea talk on the early history of the cephalosporins. Symposium proceedings were published in the first issue of Reviews of Infectious Diseases, January-February 1979. H.466 1979. Includes draft by Abraham on ‘Fleming’s Discovery’ for Reviewsof Infectious Diseases. H.467 1980-1984. H.468 1985. Includes partial Finland Lecture on the B-lactam antibiotics. draft, pp14-23, probably for Abraham’s 1985 Maxwell H.469 1988, 1993. H.470, H.471 Lederle Laboratories 1959-1963 Correspondence with colleagues at Lederle Laboratories, Pearl River, New York. H.470 1959-1960. H.471 1961-1963. H.472-H.476 Massachusetts Institute of Technology 1973-1991 Correspondence Technologyre research, visits, publications etc. colleagues with at the Massachusetts Institute of H.472 1973-1977. E.P. Abraham NCUACS 103/2/02 184 Correspondence H.473 1978-1979. H.474 1980-1981. Includes Abraham and N.G. Heatley’s comments on the typescript of J.C. Sheehan’s book The enchanted ring: the untold story of penicillin and Abraham’s forewordfor the book. H.475 1982. H.476 1983-1991. H.477-H.480 ‘Rutgers’ 1957-1981 Contents of folder so inscribed: correspondence with colleagues at Rutgers University, New Brunswick, New Jersey andothers. In April 1957 Abraham gave the CIBA Lectures in Microbial Biochemistry at Rutgers. His topic was ‘Biochemistry of Peptide and Steroid Antibiotics’ and they were published in book form by John Wiley and Sons, New York. H.477 Correspondencere visit to Rutgers and other US research centres on the occasion of Abraham’s CIBA Lectures, January-May 1957. H.478, H.479 Correspondence and papers re publication of lectures, June-December 1957. 2 folders. H.480 Correspondence with colleagues at Rutgers and others, 1957-1960, 1972- 1981. H.481, H.482 University of California, Berkeley 1977-1988 Correspondence with colleagues at Berkeley, principally Melvin Calvin and others at the Laboratory of Chemical Biodynamics. H.481 1977-1980. E.P. Abraham NCUACS 103/2/02 185 Correspondence H.482 1982-1988. H.483-H.493 University of Wisconsin-Madison 1973-1986 Correspondence with colleagues at Madison re research collaboration in the field of penicillin and cephalosporin biosynthesis, visits etc. Abraham’s principal correspondentis C.J. Sih of the School of Pharmacy. H.483 1973 January-April. H.484 1973 May-June. H.485 1973 July-September. H.486 1973 October-December. H.487 1974 January-June. H.488 1974 July-November. H.489 1975 January-June. H.490 1975 August-September. H.491 1977. H.492 1978. Includes papers re meeting on ‘Mechanisms of B-lactam Antibiotics’ at Madison, 15 December. H.493 1979-1986. E.P. Abraham NCUACS103/2/02 186 Correspondence H.494, H.495 USSR 1960-1984 Correspondence with colleagues re research, visits etc. H.494 1960-1962. H.495 1963-1967, 1984. H.496-H.534 SHORTERSCIENTIFIC CORRESPONDENCE (chronological sequence) 1944-1997 A chronological sequence of shorter correspondence re research, visits, publications, equipment and supplies, etc. H.496 1944, 1947, 1949. H.497 1950-1952. H.498 1953-1955. H.499 1956. H.500 1957. H.501 1958. H.502 1959. H.503 1960. E.P. Abraham NCUACS103/2/02 187 Correspondence H.504 1961. H.505 1962. H.506 1963. Includes experimental results. H.507 1964 January-June. H.508 1964 July-December. H.509 1965 January-May. Includes ‘Commentary & Dialogue’ for ?radio broadcast on a new antibiotic from the fungus cephalosporium. H.510 1965 June-November. H.511 1966. H.512 1967. H.513 1968. H.514 1969. H.515 1970-1971. H.516 1972. E.P. Abraham NCUACS103/2/02 188 Correspondence H.517 1973 January-June. H.518 1973 August-December. H.519 1974. Includes review of book on protoplasts and article on ‘Some British Contributions to Antibiotics and Progress in Chemotherapy’, both by Abraham. H.520 1975. Includes short article on the cephalosporins by Abraham for the Oxford Medical School Gazette. H.521 1976. H.522 1977. H.523 1978. H.524 1979. H.525 1980. H.526 1981-1982. H.527 1983-1985. H.528 1986-1989. E.P. Abraham NCUACS103/2/02 189 Correspondence H.529 1990-1991. H.530 1992-1993. H.531 1994. H.532 1995. H.533 1996-1998. H.534 N.d. H.535-H.563 REFERENCES AND RECOMMENDATIONS 1958-1996 H.535-H.549 Miscellaneous correspondence and papers re appointments, promotions, grant applications etc, 1958-1996. H.535 1958, 1964-1966. H.536 1967-1969. H.537 1970-1971. H.538 1972-1976. H.539 1977. E.P. Abraham NCUACS103/2/02 190 Correspondence H.540 1978-1979. H.541 1980-1982. H.542 1983-1984. H.543 1985-1986. H.544, H.545 1988. 2 folders. H.546 1989. H.547 1991. H.548 1992-1994. H.549 1995-1996. H.550-H.559 Indian higher education and researchinstitutions 1961-1976 Correspondence and papersre external examining. H.550, H.551 Andhra University 1962-1964 2 folders. H.552 Banaras Hindu University 1962-1963 E.P. Abraham NCUACS103/2/02 191 Correspondence H.553-H.558 Indian Institute of Science, Bangalore 1961-1976 H.553 1961-1962. H.554 1964-1965. H.555 1965. H.556 1967-1968. H.557 1968-1969. H.558 1974-1976. H.559 University of Calcutta H.560-H.563 Malaysia 1965 1977-1994. Correspondence re external examining and refereeing for the University of Malaya. H.560 1977-1979. H.561 1984. H.562 1985-1989. H.563 1994. E.P. Abraham NCUACS 103/2/02 SECTION J NON-TEXT MATERIAL 192 J.1-J.41 J.1-J.31 PHOTOGRAPHS J.32-J.38 SLIDES J.39-J.41 VIDEOTAPES E.P. Abraham NCUACS 103/2/02 193 Non-text material J.1-J.31 PHOTOGRAPHS 1930-1995, n.d. J.1-J.15 Abraham and family J.17-J.39 Visits, events and colleagues J.1-J.15 Abraham andfamily 1930-ca 1990, n.d. J.1, J.2 2 photographs (mounted) of school hockey teams, including Abraham. The photograph in J.1 is inscribed ‘King Edward VI School. Hockey Eleven 1930’. 2 folders. J.3 J.4 J.5 J.6 J.7 J.8 J.9 Photograph (mounted) of school rugby team, including Abraham, inscribed ‘School 2nd XV 1930’. Abraham in group photograph (mounted), possibly from his undergraduate years, 1932-1936. Abraham seated ona terrace, possibly on a visit to Norway,n.d. Abraham and [?his wife] on a picnic, n.d. 2 photographs of Abraham standing in a room, location unknown, n.d. Portrait of Abraham, n.d. Abraham and his wife, inscribed on verso ‘Dr and Mrs Abraham, June 1975’. J.10 Abraham at home, inscribed ‘19 February 1978, by S. Kuwabara.’ E.P. Abraham NCUACS 103/2/02 194 Non-text material J.14 J.12 J.13 J.14 J.15 Abraham, with mountain scenery in background, possibly taken in Norway, 1979. Portrait of Abraham in later years seated at a desk, n.d. Portrait of Abraham in later years, n.d. Abraham standing on a roof top, possibly of his home, n.d. Abraham reading in a chair in later years, n.d. J.16-J.31 Visits, events and colleagues ca 1938-1995, n.d. J.16 J.17 J.18 Various photographs of Abraham and someof his colleagues and others taken at conferences and events. Photographs, one each of Abraham [ca 1938-1950]; Ernst Chain, n.d.; and Howard Florey, n.d. Group photograph of Abraham and other Royal Society medallists, 1980, inscribed ’Sir Denys Wilkinson, Professor W.F. Vinen, Dr. J.P. Wild, Sir Edward Abraham, Dr. Milstein, Professor A.W. Johnson, Sir Derek Barton, Professor Henry Harris, Professor Wright.’ Dr. C. F.J.M. Farley, Abraham received the Mullard Prize. Photograph of a portrait of Robert Robinson with inscription: ‘Pleased to have your photo in the D.P album. Original at R. Soc. rooms’, 4 November 1955. J.19 Photograph of Guy Newton, n.d. E.P. Abraham NCUACS 103/2/02 195 Non-text material J.20 J.21 J.22 J.23 J.24 J.25 Abraham and Edwin H. Flynn in front of an exhibition display. Labelled on verso: ‘Professor E.P. Abraham, whowasinvolvedin the early development work on the cephalosporins in Indianapolis. He is shown with Dr. Edwin H. Flynn, one ofthe Lilly scientists who contributed to the developmentof this new antibiotic ‘family’. N.d. recently visited in Oxford, Eli Lilly Abraham and Edwin H. Flynn in front of an exhibition display. Labelled on verso as in J.20. Photograph of Abraham’s wife with various people, including Henry Harris, n.d. Abraham, in later years, seated in an audience at a ?conference, n.d. Photograph of Abraham with Indian scientists, taken during his visit to India in January 1985. The namesof the Indian scientists, as inscribed on verso, are Dr R.K. Nand, Dr P.V. Deshmukb, Dr Rama Rao (from National Chemical Laboratory), Dr P.S. Borkar, Dr N.R. Chatterjee’. This appears to have been taken on Abraham's visit to India in January / February 1985 (see F.62-F.67). Group photograph of Abraham and colleagues inscribed ‘Sir Edward Abraham's visit to the Hope Library [Oxford] on Tuesday, October 10th 1989. Dr. F.B. Atkins, Curator of Mineralogical Collections; Dr. T.S. Kemp, Curator of Zoological Collections; Prof. D. Spencer Smith, Hope Professor, Prof. J.D.C. McConnell, Dept. of Earth Sciences; Sir Edward Abraham; Dr. W.J. Kennedy, Curator of Geological Collections; Dr. S.J. Simpson, Principal Curator; Prof. G.A. Harrison, Chairman of the Committee for Scientific Collections.’ J.26, J.27 Award of Honorary Doctor of Science Degree ceremony at Strathclyde University, 13 July 1989. See also J.39. J.26 Abraham and other Honorary graduands, including Jack Baldwin. E.P. Abraham NCUACS 103/2/02 196 J.27 J.28 J.29 Non-text material Abraham with Chancellor of Strathclyde University. ’50 Years of Technische Universitat Berlin, West Berlin, 9-12 September 1980. Application’, Penicillin a symposium organized by the Various photographs taken at the symposium, contents of an envelope inscribed ‘Photographs Berlin, sent 1990’, sent from the Technical University of Berlin’. Included is one of Abraham delivering a lecture. See F.75-F.81 for correspondence and papers re the symposium. International meeting on ‘Trends in Microbial Resistance to B-Lactam Antibiotics: Molecular Aspects and Clinical Implications’, held in L’Aquila and Rome, 12-15 May 1990. Photograph of Abraham, inscribed ‘Int. Congress T.M.R.A-L’Aquila and Rome May 12-15 1990.’ See H.376, H.377 for correspondence re this meeting. J.30 Visit by Abraham to King Edward VI School, Southampton, his old school. Various photographs, contents of an envelopeinscribed ‘Portrait by Daphne Tod, Sent 1991’. J.31 Photograph inscribed ‘John Walker, Admission to R. S. 1995’. J.32-J.38 SLIDES J.32-J.34 Lantern Slides 1978, n.d. Undated J.32 J.33 J.34 1 box of 3 lantern slides contained in a box labelled ‘Pen. Chem.’ Slides used for a lecture. 1 box of 41 lantern slides usedtoillustrate a lecture or lectures on penicillin. 1 box of 13 slides labelled ‘Ceph. Mycelin Electron Micrographs’. E.P. Abraham NCUACS 103/2/02 Non-text material J.35-J.38 Lecture Slides 197 1978 J.35 J.36 J.37 J.38 1 box labelled ‘Prof. Abraham’ containing 18 slides. Some slides are dated 1978. 1 box labelled ‘Sulphanilamide other antibiotics-bioconversion’ containing 11 slides. box 1 slides Pseudomonas Enzyme’. of 14 labelled ‘Pseudomonas B-Lactam’ and ‘Mary 1 box labelled’ Set 1 Baldwin’ and ‘B-Lactamases’ containing 16 slides. J.39-J.41 VIDEOTAPES 1989, 1990 J.39 J.40 J.44 Honorary Doctor of Science Degree ceremonyat Strathclyde University, 13 July official photographs of the ceremonyat J.26, J.27. 1989. Abraham was one of the graduands. See also Series of lectures organised to celebrate the 50th anniversary of the publication of a paper on the production and therapeutic application of penicillin. The venue was the Sir William Dunn School of Pathology and speakers included Henry Harris, Norman Heatley and Abraham. The main topic was the creation of the Dunn School, research and production of penicillin. See F.82, F.83 for further material relating to this event. ‘Conversation with Eminent Biochemists, E.P. Abraham in conversation with R. Thomas, Imperial College London, 1 May 1990. The title of the videois ‘Penicillin and after, the Rise of the Antibiotic Era’. Video recorded for the UK Biochemical Society archives. bres E.P. Abraham NCUACS103/2/02 198 Non-text material In the conversation Abraham recollects parts of his early career, giving anecdotes, and gives a detailed account of the developmentof penicillin and the of correspondence. cephalosporins. The video case also contains two pieces See G.22-G.26 for further material relating to this interview. J.42 J.43 J.44 ‘The Action of Antibodies on Bacteria’. ‘Cephalosporins in Perspective’. ‘Inca balloon footage’. E.P. Abraham NCUACS 103/2/02 INDEX OF CORRESPONDENTS 199 ABBOTT LABORATORIES H.443-H.446 ACADEMIC PRESSINC. (LONDON) ACHESON, R.M. ADAM AND CHARLES BLACK LTD ADIS PRESS LTD ALBERT,Adrien ALBERTI, Carlo G. ALDERTON, Gordon ALTON, Jeannine Beatrice AMBLER, Richard P. C.613, D.123, D.275, F.41, H.512 See also C.649-C-664 H.218 D.91, D.134 D.236, D.237, D.239 H.337, H.340 H.367 H.442 A.104 H.9 See also H.75 AMERICAN ACADEMY OF ARTS AND SCIENCES G.1-G.5 AMERICAN CYANAMID COMPANY H.444, H.445, H.503 AMERICAN PHARMACEUTICAL SOCIETY ANSLOW, Gladys A. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY ANWAR, Rashid A. ARNSTEIN, H.R.V. H.456 H.477 F.20 H.112 G.68 ASIAN CONGRESS OF PHARMACOLOGY F.62, F.63, H.515 See also F.65-F.67 ASSOCIATION FOR SCIENCE EDUCATION E.62 ASTRA PHARMACEUTICALS AB H.433-H.435, H.438, H.498 AUSTRALASIAN JOURNAL OF PHARMACY H.340 AUSTRALIAN NATIONAL UNIVERSITY D.34, D.46, G.6-G.20 AUSTRIAN, Robert AZIZ, Ungku A. H.508, H.510 H.422 E.P. Abraham NCUACS 103/2/02 200 Index of correspondents BACHMANN, Lawrence P. BADDILEY, Sir James BAKER, John Randal BAKER, Warren Leslie BAKER, Wilson F.82 H.98 D.41, D.42, D.62 H.14 C.188, G.70, H.228, H.229, H.519 BALDWIN, Graham Sherard G.7, H.2-H.11, H.363 BALDWIN, Sir Jack Edward BALLIO, A. BANYARD, Michael R.C. BARBER, Mary BARD, Basil J.A. BARKER, G.R. BARKER, S.A. BARNES, John Morrisson BARTLEY,W. BATCHELOR, F.R. BAUER, Karl BAZELEY,P.L. BAXTER, R. BEECHAM PHARMACEUTICALS BEECHAM RESEARCH LABORATORIESLTD BEESON, Paul Bruce C.455, C.457, C.460, C.520, C.523, C.625-C.628, C.688, C.695, C.912, C.913, F.75, G.63, G.78, H.126, H.301, H.472, H.525, H.526 See also C.696, C.697, H.533 H.369 G.7 See H.503, H.505 H.184, H.191 H.12 H.213 D.53, D.54, H.313 See H.504 H.506 H.364 H.336 H.493 D.135 C.304, C.305, H.184, H.506, H.514 D.58, D.162 E.P. Abraham NCUACS 103/2/02 201 Index of correspondents BENEDICT,Robert G. BEN-ET, G. BERGMEYER, J. BERKS, Jonathan BERKS, Mary (née McPHAIL) BERNHEIMER, Alan W. BERNLOHR, Robert W. BETINA,Vladimir H.441 H.142 H.525 H.19 H.12-H.19 C.991 H.447 F.10, H.20, H.191 See also H.502 BETTER BUSINESS PROMOTION INC. H.413, H.414 BEVAN, E.A. BICKEL,H. BIDE, Sir Austin Ernest BINON, F. BIOCHEMICAL JOURNAL BIOCHEMICAL SOCIETY BIOCHEMIE BIOESSAYS BIRCH, Arthur John BLACK,Sir Douglas Andrew Kilgour BLACKWELL, Carol Mary H.17 F.12 D.137 H.343 C.323, D.117, D.118, D.125, D.127, D.221, D.242, D.271- D.274, H.478 See also H.500 D.131, F.61, G.21-G.26 F.57 D.247 See H.501, H.502 D.165 H.21 BLAKE, Robert William Norman, Baron A.26, D.106 BLAKEWAY,John D. BLAXTER, Sir Kenneth Lyon BLAZEJ, Anton BLEANEY,Roger Clive H.185 H.536 H.359 H.22-H.29 E.P. Abraham NCUACS 103/2/02 ° 202 Index of correspondents BLOCH, Konrad BODANSZKY,Miklos BOHONOS, Nestor BOMAN, Hans G. BOND, Godfrey W. BOOTS PURE DRUG CO. LTD G.1, G.2, H.469 F.9,H.512 H.448, H.470, H.471, H.477, H.502, H.507 H.434, H.435 H.260 H.506 BORN, GustavVictor Rudolf C.928, G.61, H.109 BOROWSKI, Edward BOYS, Omar R. BRADFORD, Harry F. BRANDL, Ernst BRANNAN, Sarah BRAZHNIKOVA, M. BRIGHTWELL, Malcolm BRIGHTWELL,R. BRISTOL-MYERS COMPANY BRITISH BROADCASTING CORPORATION BRITISH COUNCIL BRITISH MEDICAL JOURNAL H.50, H.51 H.185 F.76, G.22-G.25 F.13, F.57 H.30 H.494, H.495 H.31-H.37 H.513 C.615 D.100, D.101, E.43, E.45, E.48, E.49 G.30-G.32, H.336, H.396, H.413, H.424, H.425, H.433- H.435, H.495, H.561 D.31, D.114, D.275, H.508 See also H.502 BRITISH SOCIETY FOR ANTIMICROBIAL CHEMISTRY G.33-G.39 BRITISH TECHNOLOGY GROUP see NATIONAL RESEARCH DEVELOPMENT CORPORATION BRITTON, H.G. BROTZU, Giuseppe G.24 C.1038, C.1041, F.27, H.38- H.42, H.367 See also C.412, C.426, C.1066, C.1067 E.P. Abraham NCUACS 103/2/02 203 Index of correspondents BROWN, Nigel L. BROWNE, C.A. BROWNLEE, George Gow BRUMFITT,William BRUNET, P.C.J. BRUNT, P.A. BUD, Robert BULLARD, Sir Reader William BU’LOCK,J.D. BURTON, Henry S. BUSSE, Louis W. BYCROFT, Barrie W. BYNUM, W.F. CAHN, R.S. CAIN, JamesC. CALLOW, Donald CALVIN, Melvin CAMERON, G.R. CANNON, D.L. G.65 H.43 H.44, H.268 D.59 H.92 H.508, H.510 H.533 D.62 H.85, H.256, H.511 C.470, D.75 See also C.325 H.491 H.89, H.489 G.89 H.501 See also H.498, H.503, H.504 D.136, D.137, F.7, F.9, H.385, H.388, H.395, H.396, H.399, H.413, H.435, H.461 See also H.501 D.140 H.448, H.451, H.454, H.460, H.477, H.481, H.482, H.521 See also H.501, H.504 H.499 H.518. H.519 CENTRAALBUREAU VOOR SCHIMMELCULTURES C.1041 CHAIN, Anne Beloff, Lady D.135, D.137, D.138, D.140, D.141, D.161, D.172 E.P. Abraham NCUACS 103/2/02 204 Index of correspondents CHAIN, Sir Ernst Boris CHALMERS, D.K.M. CHAS. PFIZER & CO. INC CHATTAWAY,F.W. CHAUDHURY,Ranjit Roy THE CHEMICAL SOCIETY C.179, C.197, D.164-D.166, H.259 See also C.989, H.499. H.514 D.67 C.884, C.886, H.479 H.217 F.62-F.64, H.45-H.49, H.247, H.336, H.378, H.379, H.424, H.425, H.450 See also H.381 C.884, C.885, C.887, D.275, G.40-G.44 CHEMISTRY IN BRITAIN H.192, H.194 CHEN Han Yuan CHEN Yee Foong CHIBNALL,Albert Charles CHINESE JOURNAL OF ANTIBIOTICS CHMARA,Henryk CHRISTIAN, John Wyrill CIBA FOUNDATION CIBA LTD H.355 H.427 H.501 H.354 H.50-H.52 G.62 G.45-G.47 C.616-C.620, C.883, C.886 CIBA PHARMACEUTICALS PRODUCTS INC H.450, H.453, H.477, H.479 CIMMINO, Aldo CITRI, Nathan CLAES, P. CLARENDON PRESS, OXFORD CLARKE, HansT. COGHILL, Robert D. COHN, Zanvil A. H.374 H.509, H.515 See also H.503, H.504 H.347 H.511 See H.439 H.443-H.445 F.48, F.50 E.P. Abraham NCUACS 103/2/02 205 Index of correspondents COMMERCIAL SOLVENTS (GREATBRITAIN) LTD H.190 COOMBE, R.G. COONEY,Charles L. COOPER, Bernard A. CORCORAN, John W. CORNELIS, Guy H.53, H.54 H.130, H.474, H.475 H.109 D.191, H.201, H.462 H.55-H.66 CORNFORTH, Sir John Warcup(‘Kappa’) C.989, H.230, H.522 COUNCIL FOR SCIENCE AND SOCIETY G.48-G.57 COWEN, David L. COWEY,Alan CRAIG, Lyman C. CRAM, Donald J. CRAWFORD, K. CRESPI, R. Stephen CROOKS, Harry M., Jr CROSSLEY, Maxwell J. CROUT, David H.G. CUELLO, A.C. CUMMINS, C.S. CURTIN, John CYANAMID OF GREAT BRITAIN LIMITED D.138 G.65 H.440, H.441, H.443, H.444, H.446, H.447, H.449, H.477 See H.499 H.67 H.529 H.443-H.445 H.342 H.68-H.73 H.353 G.68 See also H.500 D.75 H.448 DAINTON, Frederick Sydney, Baron G.2, H.527, H.528 DALGLIESH, Douglas G. DATTA, Naomi DAVIDSON, B.E. DAVIDSON, J.N. H.75, H.518 H.20, H.360 H.2 G.70 E.P. Abraham NCUACS 103/2/02 206 Index of correspondents DAVIES, Richard Brownlow DAVIS, Bernard D. DEMAIN, Arnold L. H.74-H.78 G.68 H.392, H.393, H.460, H.472- H.474, H.476, H.519, H.521, H.524, H.526 DHALIWAL, S.S. H.423 DICTIONARY OF NATIONAL BIOGRAPHY D.228, D.231 DIDDENS, Heike THE DISTILLERS COMPANY LTD H.216, H.218, H.364 C.621-C.624, C.1042, C.1043 DIVISION SCIENTIFIQUE ROUSSEL UCLAF F.43, F.44 DOCTOR, V.M. DODDS, Sir (Edward) Charles DOI, Roy H. DOLL, Sir (William) Richard (Shaboe) DOUGALL, Donald K. DRURY, Sir Alan Nigel DUNCAN, Margaret Janet DYKE, Keith G.H. DYSON PERINS LABORATORY E.R. SQUIBB & SONS INC. EBERT, Robert H. EDWARDS, Giles F. StL. EDWARDS, Sir Ronald Stanley ELI LILLY AND COMPANY H.378 D.48 H.463 H.259 H.79, H.336, H.340 See also H.499 D.41 H.80 H.3, H.81 C.625-C.632 E.51, F.58 D.59, D.162 H.82-H.84 B.42, D.61 C.362, C.485, C.505, C.633- C.881 passim, H.85, H.89, H.184, H.337, H.446, H.452, H.477, H.493 ELSEVIER PUBLISHING COMPANY D.275, D.276, H.519 E.P. Abraham NCUACS 103/2/02 207 Index of correspondents ELVIDGE, John A. EMBORG, Claus ENCICLOPEDIA MEDICA ITALIANA H.23 H.363 D.11 ENCYCLOPEDIA AMERICANA F.10, H.456 ENDEAVOUR ENNOR, Sir A. Hugh ERDTMAN, Gunhild ERDTMAN, Holger ERICSON, Hans ERIKSEN, K. Riewarts ETTLINGER, L. EUROPEAN SYMPOSIUM ON BIO-ORGANIC CHEMISTRY (ESBOC) EVANS, Sir David Gwynne EULER, Hans von FALK, Leslie A. FARQUHARSON, John FARRAR, E.J. FAWCETT, Patricia Angela FEBS LETTERS FENNER, Frank FILDES, Sir Paul Gordon FINLAND, Maxwell FISHER, Adrian John FITZGERALD, Robert J. D.2-D.10, D.130, D.180 D.42, H.336, H.338 H.438, H.496, H.504 H.501 D.162, H.434 H.497, H.505, H.506 H.197 F.24, F.25 H.32 A.18, G.23 See also H.500 D.76, H.452 H.184 H.190 H.85-H.91 D.227 D.62, H.342 D.49, H.308, H.507, H.511, H.512 D.59, H.235, H.273, H.430, H.458 See also H.452, H.468 H.92-H.97 H.442 E.P. Abraham NCUACS 103/2/02 208 Index of correspondents FLEMING, Sir Alexander FLEMING, Peter C. FLOREY, Howard Walter, Baron FLOREY,Margaret, Lady FLOREY,MaryEthel, Lady FLOSS, Heinz G. FLYNN, Edwin H. FOLKSON, Aleck FORD, Brian J. THE FORD FOUNDATION FOWDEN, Sir Leslie See H.497 H.350 C.300, C.358, C.362, C.466, C.471, C.504, C.893, C.1038, C.1044, C.1048, C.1070, D.42, D.47, D.66, D.70-D.75, D.139, D.164, H.477 See also D.76, H.500, H.512 D.48, D.49, D.57, D.63, D.103, D.105, D.162, H.162 D.70, D.71, D.103 H.415 C.477, F.10, H.184, H.191, H.461 H.307, H.308, H.310, H.313 H.520 H.449, H.454, H.461, H.516, H.520 G.60, H.513, H.514, H.541 See also H.506 FRAMM, Joachim H.513, H.518 FRANK, Sir (Frederick) Charles FREEMAN, Richard F. FREESE, Ernst FUJISAWA,Y. FUJISAWA PHARMACEUTICAL CO. LTD FUKUMURA,Takashi FULLER, Keith W. FULTON, John Farquar FUNDER, Sigurd G.63 H.98 H.85 H.519 C.488, C.510, H.385, H.388, H.389, H.391, H.401, H.404, H.409, H.411, H.412 H.99, H.402-H.404, H.409, H.411 H.100 D.70-D.72 H.498 E.P. Abraham NCUACS 103/2/02 209 Index of correspondents FURTH, AnnaJ. H.101-H.107, H.413 GADDUM, Sir John Henry GAIT, M.J. GALE, Ernest Frederick GARDNER, Arthur Duncan GARDNER, Joan GARROD, Lawrence Paul GAUCHER, G.M. GAUSE, G.F. GEIGY RESEARCH LABORATORIES GENERAL ELECTRIC COMPANY GHUYSEN, Jean-Marie GIBSON, William C. GILVARG, Charles GLAXO GROUP LTD GLAXO LABORATORIES LTD GLAXO RESEARCH LTD GLOVER, S.W. GLYNN, M.F. GMELIN, Rolf GODTFREDSEN, Sven GODTFREDSEN, W.O. H.507 H.214 C.964, C.965, C.967, G.68, G.70, H.219 See also H.500, H.505 D.52, D.61 See H.319, H.320 D.48 C.341, C.399, D.61, D.64, D.104, H.511, H.505 See also H.502, H.506 H.353 H.494, H.495 See also H.493 H.450-H.452 H.446 H.108, H.347, H.514 D.50 H.142, H.213, H.216, H.217, H.396, H.519 C.488, C.882-C.913, G.27 C.231, C.304, C.305, C.363, C.1048, G.68, H.186, H.191 See also H.501 G.40 G.81, H.143 H.109 H.508, H.509 H.363 H.361, H.363, H.505 See also H.508 E.P. Abraham NCUACS 103/2/02 210 Index of correspondents GOLDBLITH, Samuel A. GOODMAN, Arnold Abraham, Baron GOODWIN, Trevor Walworth GORDON, Siamon GORE, Pamela Jean Marian GOTTLEIB, David GOULDEN, Steve A. GOWANS, Sir James Learmonth H.476, H.482 D.139 G.21, H.21 F.82 H.111 D.275, H.455, H.456 H.186, H.191 H.527 GOWING, Margaret Mary B.78, D.64, D.135, D.163 GRAHAM, Christopher Forbes GRASSI, Giuliana Gialdroni GREAT BRITAIN AND NORTHERN IRELAND H.525 F.26, F.27, F.30 MINISTRY OF HEALTH H.495 GREEN, Vivian Hubert Howerd B.39, B.40, B.44, H.323 GREENSTEIN, Jesse P. GREGORY,Roderic Alfred GROGER, D. GROSKLAGS, J.H. GRUCHY, G. Carl de GUILLET, James GUNETILEKE, Kapugama Geeganage GUTFREUND, Herbert HADDOW, Sir Alexander HALE, Clifford William H.447 H.195, H.519 H.364, H.522 H.454 D.59, H.342 H.353 H.112-H.115 C.964 See also H.498, H.501 H.306 C.287-C.307 passim, C.309, C.1043, C.1045, C.1046, D.13 HAMILTON-MILLER See MILLER E.P. Abraham NCUACS 103/2/02 211 Index of correspondents HANBURY,Harold HANCOCK,R. HANES, Charles Samuel HANKS, John H. HARE, Ronald B.53, H.507 H.452, H.453 H.112 H.479 D.61 HARINGTON, Sir Charles Robert C.326, C.330, C.1044 HARLEY,John Laker HARRE,H.R. HARRIS, Sir Henry HARTLEY,Brian Selby HARUNG, Harald Steinar HASH, John H. HASHIMOTO, Masashi HASSALL, Cedric Herbert HAYES, William HEATH, Sir Edward Richard George HEATLEY, Norman George HEDEGAARD, Jens HEIDELBERGER, Charles HEIWINKEL, Heinz HEMING, A.E. HEN Nga Been H.519, H.524 See H.512 G.58, G.59, H.116-H.118 See also H.321, H.499, H.503, H.504, J.48 H.99 H.518 H.515 H.412 G.65, H.512 See also H.503 G.60 D.165 A.102, A.103, B.40, B.49, C.1039, C.1041, D.70, D.71, D.76, D.101, D.104, D.138, H.119-H.121, H.331 See also J.48 H.362 H.439, H.440, H.449 See also H.337, H.338 H.498, H.504 H.337 H.423-H.425 HENDERSON, David Willis Wilson C.477, C.929, C.931, C.990 E.P. Abraham NCUACS 103/2/02 212 Index of correspondents HENNESSEY, Robert Samuel Fleming HERBERT,Richard B. HERBERTSON, Stig HEROLD, M. HETEROCYCLES HEYNINGEN, Ruth VAN HEYNINGEN, William Edward VAN HIGUCHI, Takeru HIMSWORTH,, Sir Harold Percival C.322 G.78 H.499 H.356, H.357, H.359, H.506 H.410, H.411 H.522 D.162, H.502 H.511 C.322 HINDUSTAN ANTIBIOTICS LTD F.62, F.64, H.378-H.380 HINSHELWOOD, Sir Cyril Norman HIRD, F.J.R. HO Coy Choke HOBBY, GladysL. HODGKIN, Dorothy Mary Crowfoot HOFFMAN- LA ROCHE INC. HOLMLUND, Chester E. HOLT, Geoffrey HOLTERMAN, Hugo HOOD, J.L. Linsley HOPE, Derek B. HOPWOOD, Sir David Alan HOSTALEK,Z. HOWIE, Sir James William HUDDLESTON, Joyce Anne HUGHES, David E. G.70, H.498 H.2 H.422-H.425, H.427, H.428, H.545, H.560, H.562, H.563 H.462, H.463, H.479 C.304, C.465, C.471, C.1069, H.350, H.526 See also H.524 H.450 H.470 H.111 H.497, H.498 H.509 H.513 G.64, H.122 H.356, H.506 D.62 H.123-H.125A H.513 E.P. Abraham NCUACS 103/2/02 HUTCHINGS, B.L. IBANEZ,Felix Marti IKAWA,Miyoshi IMADA,Akira 213 Index of correspondents H.471 H.440 H.447 H.218, H.414 IMPERIAL CHEMICAL INDUSTRIES LTD C.199, C.914-C.921 INFECTIOUS DISEASES SOCIETY OF AMERICA C.952, C.959, F.16, F.17 INTERNATIONAL JOURNAL OF ENVIRONMENTAL STUDIES D.132 INTERNATIONAL SOCIETY OF CHEMOTHERAPY INTER-UNIVERSITY COUNCIL FOR HIGHER EDUCATION OVERSEAS F.54 H.535 J.A. KEMP & CO., Chartered Patent Agents H.518, H.519 JACKSON, Willis, Baron JAGO, Margaret THE JAPAN ACADEMY D.104 H.506 H.395, H.400 JAPAN ANTIBIOTICS RESEARCH ASSOCIATION H.382, H.390, H.404 JARBOE, Charles H. JAWETZ,Ernest JAYATILAKE, Gamini Senerath JEFFERSON, Sir Geoffrey JEFFERY, Jonathan JEPHCOTT,Sir Harry JOHN WILLEY & SONS LTD JOHNSON, Alan Woodworth JOHNSON, Marvin J. JOLL, James H.457 H.441 H.126-H.131 D.75 H.132-H.134, H.191 See also H.503 D.61 H.374, H.447, H.478-H.480 H.259, H.260 H.337 See H.315, H.316 E.P. Abraham NCUACS 103/2/02 214 Index of correspondents JONES, Sir Ewart Ray Herbert (‘Tim’) JONES, Hardin B. JORPES, J. Erik JOURNAL OF ANTIBIOTICS C.496, C.1089, H.231, H.256, H.391, H.518, H.522 See also H.497, H.499, H.500 H.439 H.500, H.502, H.503 See also H.501 D.277-D.281, F.52, H.188, H.193, H.390, H.391-H.393, H.396, H.411, H.419, H.420, H.459 JOURNAL OF GENERAL MICROBIOLOGY D.207, D.275, H.478 JOURNAL OF INFECTIOUS DISEASES JOURNAL OF PHARMACY AND PHARMACOLOGY KAMETANI, Tetsuji KANZAKI, Toshihiko KASCHE, V. KASIK, John E. KASS, Edward H. KATO, Koichi KATZ, Sir Bernard KATZ, Edward KAY, Robert KELLY, Brendan Kevin KENIG, Martin D.J. KENNER, George Wallace H.465 D.275 H.410, H.411 H.395, H.401 H.365 F.16, H.135-H.139, H.188 D.60, D.162, H.462, H.465- H.469, H.536 See also G.1 H.404, H.409, H.410, H.417, H.420 See also G.23 D.165, D.166 H.358, H.447-H.449, H.454, H.455, H.480 H.18 C.287-C.307 passim, C.472, C.473, C.1042, C.1043, C.1045, C.1046 See also H.499 H.140-H.148 B.81, F.22, G.60, H.182, H.191, H.192 See also H.501, H.502 E.P. Abraham NCUACS 103/2/02 215 Index of correspondents KHUON, Ernst von KIENER, Peter Alexander KISHIDA, Yukichi KITAHARA, Kakuo KITANO, Kazuaki KJAER, Anders KLEINKAUF,Horst KLENK, Grete KLUENDER. Harold KLYNE, W. KNIGHT, Bert Cyril James Gabriel KNOWLES, Jeremy Randall KNOX, James KNOX, Robert KORNBERG, Sir Hans Leo KRYNSKI, Stefan KUMMERLE, H.P. KURABAWA,Seishi KURAHASHI, Kiyoshi KURAHAWA,Shogo KUROYA, Musahiko KURTI, Nicholas KUZNETSOV, V.D. LABIA,R. LAMPEN, J. Oliver H.149 H.150-H.153 H.415 H.388 H.401, H.417 H.503, H.505 E.26, E.28, E.31, F.68, F.69, F.75, F.76, F.81, H.364, H.365, H.532, H.533 H.509 H.483-H.485 H.507 D.63 G.2, G.63, G.72, G.73, H.465-H.467, H.469, H.523 See also A.38 H.459, H.520 H.175 H.214 See H.499 A.34 H.154-H.160, H.394, H.396, H.400, H.401, H.404 H.393, H.394 H.416 H.382 A.104 H.494 H.16 H.480 E.P. Abraham NCUACS 103/2/02 216 Index of correspondents THE LANCET LANDMAN, Otto E. LANDOR, S.R. LANSING, David LEAF, Alexander LEDERBERG, Joshua LEDERLE LABORATORIES LEFEBVRE, G. LEIN, Joseph C.946 H.450-H.452 H.516, H.517 H.461 D.60 G.68 See also H.499 H.443, H.454, H.470, H.471, H.477, H.507, H.502 See also H.502 H.527 H.390, H.423, H.450, H.462, H.475 LEO LABORATORIES LTD E.62 LEO PHARMACEUTICAL PRODUCTS LTD LEONARD, F. LEWIN, J. LEWIS,G. LEWIS, Harold E. LEWIS. J.C. LEWY, Rudolf LIDDELL, Edward George Tandy (‘Pat’) LIERSCH, M. LILLY RESEARCH LABORATORIES LINNANE, Anthony W. LJUNGBERG, Sixten LODER, John W. H.361, H.363, H.504, H.505, H.508 H.450-H.452 H.439 H.516 D.40 H.497 D.138 D.49, D.58 F.39 C.883, C.886, C.994, D.121, F.10, F.20, H.442, H.443, H.446, H.447, H.461, H.484 See also C.1047 H.342, H.516 H.433 H.162 E.P. Abraham NCUACS 103/2/02 217 Index of correspondents LODER,, Patricia Bronwen LOMAKINA,Nina LONG, Alan G. LOSEL, Dorothy M. LOVE, Jack W. LOWBURY,Edward J.L. LUEGO, José Maria LUSH, Brandon McELROY,W.D. McFADZEAN, A.J.S. MACFARLANE, Robert Gwyn H.161-H.165 See also H.341 H.495 G.40 H.197 H.188, H.191, H.512 D.59, H.516 H.166-H.169, H.432 H.81 H.154 H.336 D.64, D.104, D.105, D.107, D.136, D.137, D.139, D.161, D.163, D.166, G.70, H.316 McGRAW-HILL BOOK COMPANY A.2 McHARDY,Jack MacKEITH, Ronald Charles MADDOX, Sir John Royden MAEDA, Kenji MAEGRAITH, Brian Gilmore MAGNUSSON, Staffan MAKINS, John MANDELSTAM, Joel MARCO, A. Di MARCUS, Abraham MARGREITER, Hans H.514 See also H.527 D.60, D.62 H.512 H.396, H.400-H.402 D.50 H.506 H.524 H.81, H.141, H.299, H.511, H.543 H.171, H.366 See also H.498-H.500 H.307 F.11,F.13 See also H.499-H.501, H.503 E.P. Abraham NCUACS 103/2/02 218 Index of correspondents MARKHAM, Roy G.70 MARSTON, Robert Quarles MARTIN, Sir David Christie MARTIN, Joseph J. MARTIN, Juan Francisco MASLEN, E.N. MATHISON, G.E. MAXWELL,lan Robert MEDICAL NEWS MEDICAL RESEARCH COUNCIL ANTIBIOTICS RESEARCH STATION MEISTER, Alton MELLANBY,Sir Edward MERCK & CO. INC. MERRICK, M.J. MICHEL, Charles MICHEL, G. B.39, B.40, C.959, F.50, H.170, H.459, H.463 See also H.195 D.40, D.44 H.447 H.166, H.432, H.533 H.341, H.342 H.197 H.320, H.507 D.15 C.393, C.1045, D.47, D.54, D.66-D.69, D.139, H.184 C.287-C.303, C.1042- C.1046 H.443 C.199, C.205, D.66-D.69 C.467, C.884, C.886, C.922- C.928, C.991, C.992 See also C.1047 H.520 H.267 H.218 MICROBIOLOGICAL RESEARCH ESTABLISHMENT, PORTON DOWN, WILTSHIRE C.405, C.929-C.940, C.1010 MIGLIACCI, Adele (‘Lilli’) MILES, Sir (Arnold) Ashley MILLER, C. Phillip MILLER, Duane D. MILLER, Jeremy Marcus Tom HAMILTON- H.171-H.174, H.191, H.366, H.367 D.75, H.306 H.439 H.512 H.175-H.181 See H.506 E.P. Abraham NCUACS 103/2/02 219 Index of correspondents MILLS, John MILLSTEIN, César MINGOS, D.M.P. MITCHELL, Peter Dennis MITCHISON, D.A. MITSUHASHI, S. MIYASAKI, M. MIZUSHIMA, Sanichiro MOBERG, Carol MOLE, R.H. MOORE, Stanford MORE, Robert H. MORGAN, Walter Thomas James MORIN, Robert B. MORRELL, Jack MOSES, Vivian MUIR, Helen MUNEKATA, Masanobu H.463 G.62 A.101 G.62, G.68 See also H.500 H.517 H.402, H.410-H.413 H.385, H.388 H.409 F.50 See H.498 H.337, H.439, H.442, H.447, H.500 See also H.522 H.350 H.156 H.460 H.231, H.528, H.533 H.512 H.510, H.522 H.394 MURRAY,Keith Anderson Hope, Baron D.41, D.42, D.58 NAKANO, H. NATIONAL RESEARCH DEVELOPMENT CORPORATION H.391, H.392 B.58, C.303, C.307, C.358- C.605, C.633-C.640 passim, C.666, C.684, C.922, C.923, C.930, C.947, C.977, C.978, C.980-C.984, C.1047, C.1048, C.1060-C.1062, C.1066, F.7, F.52, H.75, H.184, H.191, H.197, H.385, H.395, H.396, H.413, H.435, H.461, H.519, H.526, H.527 See also H.501 Index of correspondents E.P. Abraham NCUACS 103/2/02 NATURE NAVASHIN, S. NEEDHAM, Joseph NELSON, John D. NEUBERGER, Albert NEWTON, Anthony NEWTON, B.A. NEWTON, Guy Geoffrey Frederick NEWTON, Rosemary Enid NICKERSON, Walter J. NIEMANN, Carl NISHIDA, Minoru NOMINE, G. NOVO INDUSTRI A/S OAKSHOTT, Sir Walter Fraser OGAWARA, Hiroshi O'GRADY,Francis OHARA, M. OKADA,H. OKAMI, Yoshiro 220 D.18, D.19, D.28, D.92, D.96, D.225, D.252, D.285, D.286, H.192, H.512, H.535 H.494 C.964 See also H.502 H.473 D.137, D.140, D.141, H.507 See also H.311 H.195 G.68 C.290, C.294, C.297, C.331, C.359, C.362, C.467, C.470, C.475, C.478, C.487, C.488, C.890, C.893, C.990, C.1042, C.1043, C.1045, C.1047, C.1048, F.9, H.161, H.182-H.196, H.302 H.191-H.194, H.516 H.477 H.439 H.391 H.343 H.363 B.41, B.53 See also B.56 H.410, H.411, H.413 E.29, H.517-H.519 H.388, H.389 H.393 H.259, H.260, H.261, H.392, H.401, H.402, H.404, H.410, H.411, H.417-H.419 OKI, Michinori H.267 E.P. Abraham NCUACS 103/2/02 221 Index of correspondents OLLIS, William David OLSON, Birger H. ORATORE, Arduino O’SULLIVAN, Joseph OTSUKA,Hideo OWEN, David Anthony Llewellyn OWEN, John B. OWEN. SamuelGriffith THE OXFORD SOCIETY OXFORD UNIVERSITY PRESS PAGE, M.1. PAGE, WHITE & FARRER, Chartered Patent Agents PAINE, Tom PALISSA, Harriet PANG Chi-Pui (‘Calvin’) PARK, JamesT. PARKE, DAVIS & COMPANY PARKER, Charles W. PARRY, Adam PARRY, BarbaraLillian PARRY, Catherine C.977-C.986, D.63, G.61, H.508 H.444, H.445, H.450 H.376 H.197-H.201 H.409 D.165 B.38 H.170 D.95, D.103 D.233, D.234, D.287, H.231, H.515 H.523 H.511 H.446 H.528 H.202-H.212 H.212 H.443-H.445 H.452, H.453 H.460 A.109, A.110 See also H.517 A.109 PATON, Sir William Drummond Macdonald A.99, E.6, G.61, H.319, H.324-H.326 PATTERSON, Ernest L. PAYNE, J.W. PEBERDY,John F. H.471 H.218 H.431 E.P. Abraham NCUACS 103/2/02 222 Index of correspondents PEIERLS, Sir Rudolf Ernst PELCZAR, Michael J., Jr PELLING, Margaret PENNEY,William George, Baron PERGAMON PRESS LTD PERHAM, Richard Nelson PERLMAN, David PERUTZ, Max Ferdinand PETERSON, W.H. PFIZER INC. PFIZER LTD PHARMACOLOGICAL REVIEWS PHILLIPS, Charles Garrett PHILLIPS, David Chilton, Baron PICKERING, Sir George PIRIE, Antoinette (‘Tony’) G.61 H.464, H.521 H.525 D.140 H.507 G.72 D.59, F.9, F.10, F.11, H.187, H.188, H.191, H.298, H.300, H.459, H.460, H.484, H.485, H.491, H.492, H.511 See also H.448 D.167, D.226 H.445, H.447 C.941-C.943 H.444 C.282 H.306-H.316, H.318, H.319, H.321, H.323, H.324, H.331 D.136, D.139, D.140, G.63, H.2, H.513, H.505, H.524 H.508 H.290 PIRIE, Norman Wingate(‘Bill’) D.45, D.58, H.378 PISANO, Michael A. POLLOCK, Martin Rivers POMERAT, Gerard P. PORATH, Jerker PORTER, Robert H.448, H.449. H.453, H.463, H.514 See also H.517 C.323-C.333, C.968-C.971, F.9, F.10, G.70-G.72, H.75, H.81, H.510, H.511 See also H.501 H.439 H.498 G.6-G.20 E.P. Abraham NCUACS 103/2/02 223 Index of correspondents PORTER, Rodney Robert PORTER, Ruth POSTGATE, John Raymond POUND, Allan W. PREOBRAJENSKAYA, T.P. PREMABAI, M. PRICE, J.R. QUAYLE, John Rodney QUEENER, Stephen W. QUINN, Jack A. RAKE, Geoffrey W. RAKHIT, S. RAMALINGASWAMI, Vulimiri RANDLE, Sir Philip John RAPER, Kenneth B. RENKONEN, K.O. REVIEWS OF INFECTIOUS DISEASES REYNOLDS, Thelma M. RICHARDS, Eva, Lady RICHARDS, Sir Rex Edward RICHARDSON, Elliot Lee RICHMOND, Sir Mark Henry RINEHART, Kenneth L., Jr RINGROSE, Peter S. RIVETT, Robert W. D.131 H.470 See also H.502 H.98 H.342 H.494 H.378 H.335, H.336 G.71 F.52, H.128 F.7, F.9, F.10, H.449, H.454, H.461, H.516, H.520 See also H.512 C.946 H.351, H.353 G.65 G.65, H.527 H.441, H.493 H.498 H.466, H.467 H.338 H.69 G.61, H.513 See also H.466 H.170 D.58, H.16, H.227, H.525 H.455 H.217, H.218 H.446 E.P. Abraham NCUACS 103/2/02 224 Index of correspondents ROBERTSON, J.S. ROBERTSON, JamesS. ROBINSON, Sir Robert ROBINSON, Stearn, Lady ROCHE PRODUCTS LTD ROCKEFELLER FOUNDATION ROGERS, David E. ROGERS, HowardJ. ROSE, Francis Leslie H.340 D.41 C.186, C.188, C.197, C.199, C.205, C.508, D.63, D.166, H.228-H.231, H.335, H.508, H.519 See also C.989, H.502, H.503 H.230 H.217. H.218 H.369, H.370, H.439, H.458, H.460 B.40 H.81 C.915-C.921 ROSENHEIM, Max Leonard, Baron D.59, H.307-H.310, H.313 ROYAL COLLEGE OF PHYSICIANS ROYALINSTITUTE OF CHEMISTRY ROYAL SOCIETY F.84 See also F.85 G.42, H.541 A.27, A.33, D.40, D.45, D.47, D.53, D.54, D.57, D.135, D.141, E.35, F.62, F.63, G.27, G.58-G.73, H.256, H.261, H.383, H.385, H.422, H.538, H.543, H.544 ROYAL SOCIETY OF CHEMISTRY G.74-G.78, H.545 RUDINGER, J. RUSSELL, Peter E. SABATH, Leon David (‘Lee’) SAINO, Yushi H.357, H.359 See also H.504, H.505 D.64 C.400, C.949, F.9, F.16, F.82, H.191, H.232-H.246, H.372, H.373, H.461, H.536 See also H.451-H.453, H.509 H.414 E.P. Abraham NCUACS 103/2/02 225 Index of correspondents SALTON, Milton Robert James SANGER, Frederick SANKAWA,Ushio SAUBER, K. SAUGMAN, Per SAUKKONEN, Jussi J. SAWADA,Yosuke SCHAAF, C. Hart SCHAEFFER, Pierre SCHAFFNER, Carl P. SCHOENTAL,Regina SCHON, Sir Frank SCIENCE JOURNAL SCIENTIFIC AMERICAN SELWYN, Sydney SEXTON, W.A. SHALL, Sydney SHAMMA, Maurice SHARPLESS, K. Barry SHAW, Robert W. SHEEHAN, John Clark SHIBA, Tetsuo SHIBATA,S. SHORTER, John SIDDIQI, Obaid SIDDIQUI, Salimuzzaman G.68 See also H.501 C.964, G.71 H.420 F.69 B.39, B.41, D.63 H.505 H.473 H.247, H.248, H.336, H.337 See also H.502, H.503, H.515 C.990, C.992 H.480 G.65 D.59 H.510 D.183, D.184 H.522, H.523 C.914-C.919 H.31 H.126 H.267 H.516 H.267, H.443, H.446, H.473- H.475 H.409 H.389 G.75 F.64 H.378 E.P. Abraham NCUACS 103/2/02 226 Index of correspondents SIH, Charles J. SIM Tiow Suan SIMMONDS, Alan SINCLAIR, Hugh Macdonald SJOBERG, Berndt SMITH, A.T.H. ROBB- SMITH, Emil L. SMITH, Ernest Lester SMITH, John Maynard SMITH KLINE & FRENCH LABORATORIES SNELL, Eric S. SNYDER, Eugene E. F.5, F.7, F.9, H.103, H.298, H.447, H.460, H.483-H.493, H.520 H.425, H.427, H.428 F.82 D.61 H.433, H.435, H.438 See H.321 G.2 G.68 G.71 C.884, C.944, C.945, H.452, H.461 D.60 B.40, H.439, H.440, H.449, H.462, H.463, H.517-H.519, H.522, H.529 SOCIETAITALIANA DI CHEMIOTERAPIA F.26, F.27, F.30, F.31 SOCIETY FOR GENERAL MICROBIOLOGY SOCIETY FOR INDUSTRIAL MICROBIOLOGY SOCIETY OF CHEMICAL INDUSTRY SODA,Kenji SONDHEIMER, E. G.79-G.81 E.23, E.24 E.62 H.401 See H.448, H.449 SOUTHWOOD, Sir (Thomas) Richard (Edmund) G.1, G.73 SPARROW, John Hanbury Angus SPENCER, Brian SPRINGER-VERLAG SPOONER, D.F. SQUIBB INSTITUTE FOR MEDICAL RESEARCH D.59 F.33 D.216, H.476, H.512 H.506 C.633, C.884, C.886, C.946- C.962, F.9 See also C.1047, H.500 E.P. Abraham NCUACS 103/2/02 227 Index of correspondents STAUFFER, J.F. STEIN, William H. STEINMAN, Harry G. STEMBERGER, Heinrich STEVENS, Carl M. STEVENS, LANGNER, PARRY & ROLLINSON, Chartered Patent Agents STEWARD, Frederick Campion STEWART, Gordon Thallon STODOLA,Frank H. STRAHS, Gerald STROMINGER, JackL. STURGESS, Elizabeth SUHADOLNIK,R.J. SUMIKI, Yusuke SUTHERLAND, I.W. SUTHERLAND, Dame Lucy Stuart SWISS SOCIETY OF MICROBIOLOGY SYMINGTON, T. SYNGE, Richard Laurence Millington TAKANO, Tadayoshi TAKEDA, Katsuo TANENBAUM, Stuart W. TANSEY, E.M. (‘Tilli’) H.448, H.453 H.440, H.446 H.452-H.454, H.508 H.514, H.515 H.249-H.253 H.511 H.448 C.293, C.294, C.1065, D.63, D.128, E.47, H.455-H.459, H.506-H.508, H.513, H.534 See also H.504, H.505 H.448 H.453 H.456, H.465 H.517 H.448, H.449 H.382 H.62, H.126 D.63 F.38, F.39 H.310 H.497, H.498 See also H.500 H.388, H.389, H.393, H.394, H.403, H.404, H.409, H.412, H.413 H.415 H.448 G.90 E.P. Abraham NCUACS 103/2/02 228 Index of correspondents TAYLOR, Marilyn THOMAS, Robert THOMPSON, Penelope, Lady THORNILEY, Maureen Susan H.532 G.22, H.516, H.525 H.516 H.254, H.255 THE TIMES LITERARY SUPPLEMENT D.128, D.129, D.224 TISHLER, Max TODD, Alexander Robertus, Baron TODRICK,A. TOSONI, A.L. TOYO RAYON COMPANY TREND, Burke St John, Baron TRENDSIN BIOCHEMICAL SCIENCES TRIBUNA MEDICA TROWN, Patrick W. TSUDA, Kyosuke TULLY, Michael TURNER, John M. TWYFORD LABORATORIES LTD UEDA, Yasushi UMEZAWA, Hamao UMEZAWA, Kazuo UNGAR, J. UNIVERSITY OF TOKYO PRESS THE UPJOHN COMPANY USHER, John James D.62 See H.502 H.529 H.350 C.1042 D.161 H.515 H.430 H.454, H.493 H.384, H.388 H.7 H.21 H.508 H.413 G.64, H.216, H.256-H.266, H.268, H.383, H.384, H.388- H.393, H.395, H.396, H.400- H.402, H.404, H.410, H.418 See also H.155 A.34, H.267, H.268, H.419 H.368 C.960 C.963, H.452, H.454 H.269-H.281 E.P. Abraham NCUACS 103/2/02 229 Index of correspondents VANARENDONK,A.M. H.452, H.477 See also H.510 VANDAMME, Erick Jerome Maurice Cornelius H.142, H.282-H.286, H.348 VANDERHAEGHE, H. VANEK, Zdenko VAUGHAN, Dame Janet Maria VEALE, Douglas VELLA, Luciano VERMA, R.D. VLIETINCK,A.J. VOROS, Laszlé WAKAZAWA, T. WALDMANN, Herman WALEY, Stephen Gerald WALKER, Sir John Ernest WALLMARK,Gésta WALSHE, J.M. WARREN, S.C. WATANABE, Tetsuo WATERWORTH, Pamela M. WATSON, K.C. WEISS, David W. WELCH, Arnold D. WELLCOME FOUNDATION LTD H.287, H.288, H.347, H.508, H.513, H.514, H.516, H.517, H.534 H.356-H.360 G.64, H.509 D.73 H.369 H.378 H.289 H.506 H.404 A.38, A.39 H.290-H.297 H.298-H.301 H.509 H.185 H.302, H.385 H.382 H.518 H.506, H.509 H.337, H.338, H.449 C.401 H.505, H.506 WELLCOME RESEARCH LABORATORIES H.499 E.P. Abraham NCUACS 103/2/02 230 Index of correspondents WELLCOME TRUST WHALLEY,W. Basil WHELAN, W.J. WHITE, E.P. WHITE, Peter J. WHITE, Robert Lester WHITEMAN, Patricia Angela (née Fawcett) WHITTENBURG, John V. WIELAND, O. WIGGINS, L.F. WILD, D.G. WILKINSON, Sir Geoffrey WILLIAMS, J. David WILLIAMS, Trevor Illtyd G.82-G.90, H.323, H.335, H.383-H.385 H.538 See also H.500 F.24 H.374 H.337 H.65 H.303-H.305 See FAWCETT H.471, H.503 H.43 H.371 H.90 A.97, C.1067 See also H.516 G.33, G.34 D.91, D.134. H.231, H.438 See also H.190, H.500 WILSON, Sir Graham Selby D.51, G.63 WINSHELL,Elaine WINTERSTEINER, O. WOODRUFF, H. Boyd H.460 H.452 E.24 WOODWARD, Robert Burns H.447, H.455, H.465, H.511 WORK, Elizabeth H.508 See also H.500 WORLD HEALTH ORGANIZATION H.20, H.45-H.47, H.495 WRETLAND, Bengt WRIGHT, R. Douglas WRIGHT, Eric H.438 D.45, D.55 H.306 E.P. Abraham NCUACS 103/2/02 231 Index of correspondents WRIGHT, S.E. WRIGHT,Winifred G. WRINCH, Dorothy WRISTON, John C., Jr WU, Henry C. WYLIE, John Anthony Hamilton YAGISAWA, Morimasa YAGISAWA, Yukimasa YAMABE, Shigeru YAMANAKA,Kunio YANKWICH, Peter E. YONEDA, Masahiko YONEHARA,Hiroshi YOSHIDA, Akira YOSHIDA,Tadashi YOUNG, Douglas W. ZAHNER, Hans ZERVAS, L. ZIMAN, John Michael H.336-H.338, H.340 H.509 H.450 See also H.504 H.448 H.217 H.306-H.334 H.419, H.420 H.382, H.390-H.392, H.396, H.402, H.411, H.459 H.409, H.412, H.415-H.417, H.421 H.382 H.439, H.442 H.409 H.385 H.415 H.413, H.418 C.758, H.87, H.486, H.487, H.490, H.520 H.214, H.218, H.364 See H.185 G.48, G.49, G.52 Catalogue of the records of the E.P. Abraham Research Fund and E.P. Abraham Cephalosporin Fund (1965-1991) by Peter Harper National Cataloguing Unit for the Archivesof Contemporary Scientists, University of Bath Bath 2002 E.P. Abraham Funds Title: Catalogue of the records of the Edward Penley Abraham Research Fund and Edward Penley Abraham Cephalosporin Fund Compiled by: Peter Harper Description level: Fonds Date of material: 1965-1991 Extent of material: 21 boxes, ca 350 items Depositedin: Bodleian Library, Oxford Reference code: GB 0161 E.P. Abraham Funds © 2002 National Cataloguing Unit for the Archives of Contemporary Scientists, University of Bath. E.P. Abraham Funds THE COMPILATION AND PRODUCTIONOF THIS CATALOGUE WAS MADE POSIBLE BY GRANTS FROM THE EDWARD PENLEY ABRAHAM RESEARCH FUND AND THE EDWARD PENLEY ABRAHAM CEPHALOSPORIN FUND. E.P. Abraham Funds ACCESS TO THE MATERIALIN THIS COLLECTION IS RESTRICTED. E.P. Abraham Funds LIST OF CONTENTS GENERAL INTRODUCTION Items Page SECTION A E.P. ABRAHAM RESEARCH FUND A.1-A.191 SECTION B E.P. ABRAHAM CEPHALOSPORIN FUND B.1-B.148 INDEX OF CORRESPONDENTS 20 30 E.P. Abraham Funds 5 GENERAL INTRODUCTION PROVENANCE The papers were received in July 2000 from the Trustees, E.P. Abraham Research Fund and E.P. Abraham Cephalosporin Fund, Sir William Dunn Schoolof Pathology, University of Oxford. OUTLINE OF THE ESTABLISHMENT OF THE TRUSTS Edward Abraham was a memberof the larger team that turned penicillin into a clinical reality at the Dunn School and went on to develop the cephalosporin class of antibiotics. Worldwide patents covering the cephalosporin group were taken out by the National Research Development Corporation (NRDC), and these eventually yielded massive royalties. Abraham diverted the greater part of his personal share of the royalty incomeinto two trusts to support further scientific research and education, especially at Oxford. In June 1965 Abraham wrote to the Registrar, University of Oxford about the NRDC royalties he was likely to receive during the next few years arising from the use of cephalosporins in medicine. At that point he could not predict whetherthe total sum would berelatively small or quite substantial though the first payment, which would probably be made in October, was not expected to be very large. He stated that it was his present intention to set up a Trust Fund so that some of the moneyinvolved might be used primarily for the benefit of the Dunn School, though also, if the sum became large enough, for other appropriate purposesin the University or Colleges at the discretion of the Trustees. His purposein writing to the Registrar was to ask whether he could see any objection on the part of the University to his proceding with such a scheme,citing the Burdon-Sanderson Pathology Trust, which was set up in 1906, as a precedent in the University for such a Trust. With his proposal welcomedby the Vice-Chancellor, with whom the Registrar discussed the proposal, Abraham was able to place the setting up of a charitable trust in the hands of his advisers. The charitable trust was called the Edward Penley Abraham Research Fund. In addition to Abraham the Rectorof Lincoln College, Oxford and the Professorof Pathology in the University of Oxford were ex officio Trustees of the Fund. At the time of the establishment of the Fund the Rector of Lincoln was Walter Fraser Oakeshott and the Professor of Pathology, Henry Harris. Abraham alone had the powerto appoint new Trustees (other than ex officio Trustees) during his lifetime. When Professor Henry Harris ceased to be Professor of Pathology on his appointment as Regius Professor of Medicinein the University of Oxford he was appointed a Trustee in his personal capacity. The Trust E.P. Abraham Funds 6 Deed, dated 17 March 1967, enabled the Trustees to support research in the medical, biological and chemical sciencesin the University of Oxford and its Colleges. The scale of the royalty payments received by Abraham madeit possible for him to establish a second charitable trust called the Edward Penley Abraham Cephalosporin Fund. The original Trustees were Abraham, George Wallace Kenner, Professor of Organic Chemistry in the University of Liverpool and Leon David Sabath M.D., then at the Harvard Medical Unit, Boston City Hospital, Massachusetts, USA. The Trust Deed, dated 15 May 1970, enabled the Trustees to support research and education in the medical, biological and chemical sciences in the University of Oxford and its Colleges and by the Royal Society. In 1977 Abraham raised the possibility in a letter to the Headmaster of his old school, King Edward VI School, Southamptonthat in certain circumstances he and his co-Trustees might be prepared to take steps to give some support to the medical, biological and chemical sciences in the school. This was welcomed by the school and the necessary Declaration of Trust was prepared the following year. At the end of 1978 Sir James Baddiley, Professor of Chemical Microbiology, University of Newcastle upon Tyne, agreedto act as Trustee in place of Professor Kenner who had died. In 1989 the E.P. Abraham Professor of Chemical Pathology in the University of Oxford, George Gow Brownlee, becamean exofficio Trustee of the Fund. DESCRIPTION OF THE MATERIAL The papers are presented in two sections corresponding to the two charitable trusts though since Abraham wasa Trustee of both Funds and they had the same accountants, bankers, solicitors and so on thedistinction is not always clear cut. The papers cover the period 1965-1991. Section A, Edward Penley Abraham Research Fund, documents the Fundfrom theinitial proposalto establish a charitable fund in 1965 to around 1990. There is documentation relating to the establishment and early history of the fund, 1965-1969, and correspondence and papers with Abraham's advisers such as accountants and solicitors. By far the largest group of papers relates to applications to the fund, 1970-1991, presented as far as possible in their original arrangement. Correspondence and papers relating to the Newton-Abraham Visiting Professorship established by the Trust form a separate sequence, 1978-1990. There are also papers for Trustees’ meetings, 1979-1990 and a set of accounts, 1967-1986. Section B, Edward Penley Abraham Cephalosporin Fund, documents the Fund from 1970, the year of its establishment, to around 1990. Byfar the largest group of papers relates to applications to the fund, 1970-1991, presented as far as possible in their original arrangement. Correspondence and papersrelating to Abraham and the Fund'srole in the establishment of Green College, Oxford form a E.P. Abraham Funds 7 separate sequence. There is also correspondence and papers with Abraham’s advisers such as accountants and solicitors, a sequence of ‘financial papers/papers for Trustees’ meetings’, 1976- 1989 and a set of accounts, 1970-1986. Thereis also an index of correspondents. Peter Harper University of Bath June 2002 E.P. Abraham Funds 8 SECTION A EDWARD PENLEY ABRAHAM RESEARCHFUND,A.1-A.191 1965-1991 The Fund was established by Abraham with royalties received from the National Research Development Corporation arising from the use of cephalosporins in medicine. In addition to Abraham the Rector of Lincoln College, Oxford and the Professorof Pathology in the University of Oxford were ex officio Trustees of the Fund. At the time of the establishmentof the Fund the Rector of Lincoln was Walter Fraser Oakeshott and the Professor of Pathology, Henry Harris. Abraham alone had the power to appoint new Trustees (other than ex officio Trustees) during his lifetime. WhenProfessor Henry Harris ceased to be Professor of Pathology on his appointment as Regius Professor of Medicine in the University of Oxford he was appointed a Trustee in his personal Capacity. The Trust Deed enabled the Trustees to support researchin the medical, biological and chemical sciencesin the University of Oxford andits Colleges. A.1-A.6 ESTABLISHMENT AND EARLY HISTORY A.7-A.114 APPLICATIONS A.115-A.131 VISITING PROFESSORSHIP A.132 BARCLAYS BANK PLC A.133-A.141 A.142-A.147 A.148-A.153 A.154 A.155 W.H. BAYLISS, SONS & CO. /KIDSONS (Chartered Accountants) NATIONAL RESEARCH DEVELOPMENT FUND/ BRITISH TECHNOLOGY GROUP ROBERT FLEMING & CO LTD/ROBERT FLEMING INVESTMENT MANAGEMENTLIMITED UNIVERSITY OF OXFORD TRUSTS POOL MOVEMENTS ON GRANTS A.156-A.172 PAPERS FOR TRUSTEES’ MEETINGS A.173-A.190 ACCOUNTS A.191 MISCELLANEOUS E.P. Abraham Funds E.P. Abraham Research Fund A.1-A.6 ESTABLISHMENT AND EARLYHISTORY 1965-1969 A.1 A.2 A.3 A.4 ‘Papers 1965’. Contents of folder so inscribed. Includes correspondence with Registrar, University of Oxford re Abraham’s proposal to set up a Trust Fund with some of the money he received as royalties from the National Research Development Corporation (NRDC) arising from the use of cephalosporins in medicine, June-July 1965. ‘Papers 1966’. Contents of folder so inscribed. Correspondencewith solicitors, accountants, NRDCetc re proposed Trust, and drafts of ‘Terms of the Trust Proposed’, 1965-1966. ‘Papers 1967’. Contents of folder so inscribed. Correspondence with solicitors, NRDC, University of Oxford Registry and Rector of Lincoln College and copy of Trust Deed for the Guy Newton Research Fund Trust, February-August 1967. ‘Papers 1968’. Contents of folder so inscribed. Correspondence with accountants, Barclays Bank Ltd, NRDC and Robert Fleming & Co Ltd, February-December 1968. A.5, A.6 ‘Papers 1969’. Contents of folder so inscribed divided into two for ease of reference. Correspondence with Rector of Lincoln College, Oxford, accountants, Barclays Bank Ltd, NRDC and Robert Fleming & Co Ltd, 1969-1970. A.7-A.114 APPLICATIONS 1970-1991 A.7 ‘Applications Trustees Receipts 1970’. Contents of folder so inscribed. Correspondence and papers, January-October 1970. E.P. Abraham Funds 10 E.P. Abraham Research Fund A.8 A.9 A.10 ‘Applications Trustees Receipts 1971’. Contents of a folder so inscribed. Correspondence andpapers, January-November 1971. ‘Applications Trustees Receipts 1972’. Contents of a folder so inscribed. Correspondence and papers, February-September 1972. ‘Applications Trustees Receipts 1973’. Contents of a folder so inscribed. Correspondence and papers, May-December 1973. A.11, A.12 ‘Applications Receipts Trustees 1974’. Contents of a folder so inscribed divided into two for ease of reference. Correspondenceand papers, 1974. A.13-A.15 ‘Applications Receipts Trustees 1975’. Contents of a folder so inscribed divided into three for ease of reference. Correspondence and papers, 1975. Include papers re endowing a professorship of chemical pathology. A.16 ‘Applications Receipts Trustees Financial Summaries 1976’. Contents of a folder so inscribed. Correspondence and papers, 1976. A.17-A.20 ‘Applications Receipts Trustees Financial Summaries 1977’. Contents of a folder so inscribed divided into four for ease of reference. Correspondence and papers, 1977. A.21-A.24 ‘Correspondence - University - NRDC 1978’. inscribed divided into four for ease of reference. Contents of folder so Correspondenceand papers, 1978. Includes papers re endowing a visiting professorship in the medical, biological and chemical sciences. E.P. Abraham Funds 11 E.P. Abraham Research Fund A.25-A.29 ‘Correspondence - University - NRDC 1979”. inscribed dividedinto five for ease of reference. Contents of folder so Correspondenceand papers, 1979. A.30-A.34 ‘Correspondence - University - NRDC Jan 1980-April 1981’. folder so inscribed dividedinto five for ease of reference. Contents of Correspondenceand papers, 1979-1981. A.35 ‘2 Applications - refused’. Contents of envelope soinscribed. Correspondenceand papers, 1980. A.36-A.42 ‘Correspondence & Completed Applications Contents of folder so inscribed divided into seven for ease of reference. April 1981-March 1982’. Correspondenceand papers, 1979-1982. A.43, A.44 ‘D. Phil. Students. April 1981 - March 1982’. Contents of folder so inscribed divided into two for ease of reference. Correspondence andpapers, 1980-1981. A.45 ‘E.P.A. Research Fund For Attention April 1981 - March 1982’. Contents of folder so inscribed. Correspondence and papers, 1981-1982. A.46-A.52 ‘Completed Applications Correspondence April 1982-1983’. folder so inscribed divided into seven for ease of reference. Contents of Correspondenceandpapers, 1979-1983. A.53 ‘D.Phil. Students April 1982-83’. Contents of folder so inscribed. Correspondence and papers, 1982. E.P. Abraham Funds 12 E.P. Abraham Research Fund A.54 Contents of untitled folder. Correspondenceand papers re application, 1981-1983. A.55-A.63 ‘Completed Applications (Correspondence) April 1983-84’. folder so inscribed dividedinto nine for ease of reference. Contents of Correspondenceand papers, 1981-1984. A.64 Contents of untitled folder. Correspondence and papers including list of D. Phil students 1983-1984, 1983. A.65-A.68 ‘Completed Applications’. Contents of folder so inscribed divided into four for ease of reference. Correspondence andpapers, 1981-1984. A.69-A.77 ‘Completed Applications’. Contents of folder so inscribed divided into nine for ease of reference. Correspondence and papers, 1980-1985. A.78-A.88 ‘Completed Applications April 1985-1986’. Contents of folder so inscribed divided into eleven for ease of reference. Correspondenceand papers, 1981-1986. A.89, A.90 ‘For Attention two for ease of reference. April 1985-86’. Contents of folder so inscribed divided into Correspondence and papers, 1983-1986. A.91-A.102 ‘Completed Applications April 1986 - December 1987’. Contents of folder so inscribed divided into twelve for ease of reference. Correspondenceandpapers, 1983-1987. E.P. Abraham Funds 13 E.P. Abraham Research Fund A.103 ‘For Attention April 1986 - December 1987’. Contents of folder so inscribed. Correspondence and papers, 1985-1987. A.104-A.113 ‘Completed Applications January 1988 - August 1989’. Contents of folder so inscribed dividedinto ten for ease of reference. Correspondenceand papers, 1984-1991. A.114 ‘For Attention January 1988 - August 1989’. Contents of folder so inscribed. Correspondence andpapers, 1986-1987. A.115-A.131 VISITING PROFESSORSHIP 1978-1990 In February Abraham wrote to the University Registrar to the effect that the E.P. Abraham Research Fundwasconsidering whetherto offer to support a Visiting Professorship in the Medical, Biological and Chemical Sciences. Welcomed by the University and the relevant Departments it was duly The established with the title Newton-Abraham Visiting Professorship. Visiting Professorship was associated with Lincoln College Oxford. Thefirst holder was A.J. Birch of the Research School of Chemistry, Australian National University, Canberra from December 1980. A.115-A.118 ‘Visiting Professorship’. Contents of folder so inscribed divided into four for easeof reference. Correspondence Professorship, 1978-1981. and papers re the establishment of the Visiting A.119-A.123 ‘Visiting Professor Electoral Board 1979-1983’. inscribed dividedinto five for ease of reference. Contents of folder so Correspondence and papers, 1979-1983. A.124-A.127 ‘Visiting Professor Electoral Board 1984-June 1990’. Contents of folder so inscribed divided into four for ease of reference. Correspondenceandpapers, 1984-1990. E.P. Abraham Funds 14 E.P. Abraham Research Fund A.128-A.131 ‘Correspondence with Visiting Professors 1981-June 1990’. folder so inscribed divided into four for ease of reference. Contents of Correspondence andpapers, 1981-1990. A.132 A.132 BARCLAYS BANK PLC 1967-1986 Miscellaneous correspondence and papers re financial administration from the Fund’s Barclay’s Bank files, 1967-1986. Includes pass bookin use 1967-1971. A.133-A.141 W.H. BAYLISS, SONS & CO. / KIDSONS (Chartered Accountants) 1968-1988 Correspondence and papers with the Fund’s accountants, W.H. Bayliss, Sons & Co. (Kidsons from September 1987). Bayliss, Sons & Co. were the accountants for the Funds established with Cephalosporin royalties and that is reflected in some of the papers listed below. A.133 1968, 1970. Includesletters to H.M. Chief Inspector of Taxes on the policy of the Trust. A.134 1971-1973. A.135 1974-1976. A.136 1977-1978 A.137 1979, 1981-1982. A.138 1983-1984. E.P. Abraham Funds 15 E.P. Abraham Research Fund A.139 1985-1986. A.140 1986. Correspondence and papers re proposed changesin tax legislation which would affect charities. A141 1987-1988. A.142-A.147 NATIONAL DEVELOPMENT RESEARCH CORPORATION/ BRITISH TECHNOLOGY GROUP 1970-1987 Includes copies of the Cephalosporin Exploitation and Revenue Sharing Accounts and related correspondence. A.142 1970-1974. A.143, A.144 1975. Principally correspondence and papers re future prospects for royalty payments. 2 folders. A.145 1976-1981. A.146 1982-1985. A.147 1986-1987. E.P. Abraham Funds 16 E.P. Abraham Research Fund A.148-A.153 ROBERT FLEMING & CO. LTD / ROBERT FLEMING INVESTMENT MANAGEMENTLTD 1970-1989 The Trustees of the E.P. Abraham Research Fund invested in the Robert Fleming Property Unit Trust. At the end of 1977 the Trustees agreed to employ Robert Fleming to provide managementfor all the current assets other than the amounts invested in the Oxford Trusts Pool or held on current accountwith the Trustees’ bankers. Correspondence and papers, 1970-1989. A.148 1970, 1976-1977. A.149, A.149A 1977-1978 Correspondence and papers re proposals for investment management. 2 folders A.150 1979, 1983. A.151 1984. A.152 1985-1987. A.153 1988-1989. A.154 A.154 UNIVERSITY OF OXFORD TRUSTS POOL 1970-1988 Correspondence and papers re the Fund’s Trusts Pool investments, 1970- 1988. E.P. Abraham Funds 17 E.P. Abraham Research Fund A.155 A.155 MOVEMENTON GRANTS 1983-1987 Annual records of ‘movement on grants’ from year ending 5 April 1983 to year ending 5 April 1987. A.156-A.172 PAPERS FOR TRUSTEES’ MEETINGS 1975-1990 Includes minutes of meetings. A.156 1975-1976. A.157 1977-1978. A.158 1979-1980. A.159 A.160 1981. 1982. A.161, A.162 1983. 2 folders. A.163, A.164 1984. 2 folders. A.165, A.166 1985. 2 folders. E.P. Abraham Funds 18 E.P. Abraham Research Fund A.167, A.168 1986. 2 folders. A.169 1987. A.170 1988. A.171 1989. A.172 1990. A.173-A.190 ACCOUNTS 1967-1986 A.173 1967. 1968. A.174 1969. A.175 1970. A.176 1971. A.177 1972. A.178 1973. A.179 1974. E.P. Abraham Funds 19 E.P. Abraham Research Fund A.180 A.181 A.182 A.183 A.184 A.185 A.186 A.187 A.188 A.189 A.190 A.191 A.191 1975. 1976. 1977. 1978. 1 January 1979 - 5 April 1980. Year ended 5 April 1981. Year ended 5 April 1982. Year ended 5 April 1983. Year ended 5 April 1984. Year ended 5 April 1985. Year ended 5 April 1986. MISCELLANEOUS 1977-1985, n.d. Miscellaneous correspondence and papers, 1977-1985,n.d. E.P. Abraham Funds 20 SECTION B EDWARD PENLEY ABRAHAM CEPAHALOSPORIN FUND, B.1-B.148 1970-1991 The Fund was established by Abraham with royalties received from the National Research Development Corporation arising from the use of cephalosporins in medicine. The original Trustees were Abraham, George Wallace Kenner, Professor of Organic Chemistry in the University of Liverpool and Leon David Sabath M.D., then at the Harvard Medical Unit, Boston City Hospital, Massachusetts, USA. The Trust Deed enabled the Trustees to support research and education in the medical, biological and chemicalsciencesin the University of Oxford andits Colleges and by the Royal Society. In 1977 Abrahamraised the possibility in a letter to the Headmasterof his old school, King Edward VI School, Southampton, (B.29) that in certain circumstances he and his co-Trustees might be prepared to take steps to give some support to the medical, biological and chemical sciences in the school. This was welcomed bythe school and the necessary Declaration of Trust was prepared the following year. At the end of 1978 Sir James Baddiley, Professor of Chemical Microbiology, University of Newcastle upon Tyne, agreedto act as Trustee in place of Professor Kenner who had died. In 1989 the E.P. Abraham Professor of Chemical Pathology in the University of Oxford, George Gow Brownlee, became an ex officio Trustee of the Fund. B.1-B.111 APPLICATIONS B.112-B.114 GREEN COLLEGE, OXFORD B.115 BARCLAYS BANK PLC B.116, B.117 W.H. BAYLISS, SONS & CO./KIDSONS (Chartered Accountants) B.118 MALLAM, LEWIS & NORRIS/MALLAM, LEWIS & TAYLOR (Solicitors) B.119, B.120 NATIONAL RESEARCH DEVELOPMENT FUND/ BRITISH TECHNOLOGY GROUP E.P. Abraham Funds 21 E.P. Abraham Cephalosporin Fund B.121, B.122 ROBERT FLEMING INVESTMENT MANAGEMENT LIMITED B.123 B.124 UNIVERSITY OF OXFORD TRUSTS POOL MOVEMENTS ON GRANTS B.125-B.132 FINANCIAL PAPERS/PAPERS FOR TRUSTEES’ MEETINGS B.133-B.148 ACCOUNTS B1-B.111 APPLICATIONS 1970-1991 Correspondence and papersre applications and related matters. B.1, B.2 ‘Applications Trustees Mallam, Lewis & Taylor [Solicitors] 1970’. Contents of folder so inscribed divided into two for reference. Correspondence and papers, 1970. Includes correspondence and papers re Trust Deed. B.3-B.6 B.7, B.8 B.9, B.10 ‘Application Contents of folder so inscribed divided into four for ease of reference. Receipts Mallam, Lewis & Taylor [Solicitors]’. Trustees Correspondence and papers, 1971. ‘Applications folder so inscribed divided into two for ease of reference. Fin. Calculations Receipts Trustees 1972’. Contents of Correspondenceand papers, 1972. ‘Applications divided into two for ease of reference. Receipts Trustees 1973’. Contents of folder so inscribed Correspondence and papers, 1973. E.P. Abraham Funds 22 E.P. Abraham Cephalosporin Fund B.11, B.12 ‘Applications divided into two for ease of reference. Receipts Trustees 1974’. Contents of folder so inscribed Correspondence and papers, 1974. B.13-B.16 ‘Applications Receipts Trustees Mallam Lewis & Norris [Solicitors] 1975’. Contents of folder so inscribed divided into four for ease of reference. Correspondence and papers, 1975. B.17-B.23 ‘Applications Receipts Trustees Financial Calculations 1976’. Contents of folder so inscribed divided into seven for ease of reference. Correspondence and papers, 1976. B.24-B.34 ‘Papers 1977 Jan-Dec’. Contents of folder so inscribed divided into eleven for ease of reference. Correspondence and papers, 1977. Includes Abraham's correspondence with Trustees and the Trust’s solicitors Mallam, Lewis & Norris. B.35-B.39 ‘Correspondence - University - Royal Society - King Edward School - St Annes - Wellcome - St Hughs -TV - Green College - Queens - Lincoln - LMH - Mr Keating - Linacre + Trustees’. Contents of folder so inscribed divided into five for ease of reference. Correspondence and papers, 1978. B.40-B.42 Correspondence and papers re support for film on the Paget-Gorman system for the problem of communication in cerebral palsy children, 1975- 1979. Contents of folder divided into three for ease of reference. B.43-B.46 ‘Correspondence Southampton] 1979’. easeof reference. Trustees KES [King Edward VI School Contents of folder so inscribed divided into four for Queens Correspondence and papers, 1978-1979. E.P. Abraham Funds 23 E.P. Abraham Cephalosporin Fund B.47-B.51 ‘Correspondence 1980 Jan-1981 April 2’. divided into five for ease of reference. Contents of folder so inscribed Correspondence and papers, 1979-1981. B.52 ‘Correspondence inscribed. 1981 April 3 - March 1982’. Contents of folder so 2 letters only, May 1981. B.53-B.57 ‘For attention 1981-2’. Contents of folder so inscribed divided into five for ease of reference. Correspondenceand papers, 1980-1982. B.58-B.60 ‘For attention April 1982-1983’. Contents of folder so inscribed divided into three for ease of reference. Correspondence and papers, 1981-1982. B.61-B.66 ‘(Correspondence) Completed Applications folder so inscribed divided into six for ease of reference. April 1982-1983’. Contents of Correspondence and papers, 1981-1983. B.67-B.69 (Correspondence) Completed Applications April 1983-4’. Contents of folder so inscribed divided into three for ease of reference. Correspondence and papers, 1982-1984. B.70 ‘Keith Murray Award Appeal Committee Minutes’. inscribed. Contents of folder so Correspondence and papers, 1982-1983. The appeal was launched to fund awards for graduate studentships at Lincoln College, Oxford in honour of Lord Murray of Newhaven, Rector of Lincoln, 1944-1953 and first Chairman of the University Grants Committee, 1953-1963. The E.P.A. Cephalosporin Fund made significant contribution to the appeal which involved the preparation of a supplementary deed. Abraham was a member of the Committee. See B.89-B.91. E.P. Abraham Funds 24 E.P. Abraham Cephalosporin Fund B.71-B.78 ‘Completed Applications 1984-85’. Contents of folder so inscribed divided into eight for ease of reference. Correspondence and papers, 1983-1985. B.79-B.86 ‘Completed Applications dividedinto eight for ease of reference. April 1985-86’. Contents of folder so inscribed Correspondence and papers, 1983-1986. B.87 B.88 ‘For Attention April 1985-86’. Contents of folder so inscribed. Correspondence and papers, 1985-1986. ‘Extra Applications 11 June 1985 outside Trust Deed etc. Should any be answered further?’. Contents of folder so inscribed. Correspondence and papers, 1983-1985. B.89-B.91 Correspondenceand papers re Keith Murray Award Fund, 1982-1985. 3 folders. See also B.70. B.92-B.99 ‘Completed Applications inscribed divided into eight for ease of reference. April 1986 - July 1987’. Contents of folder so Correspondence and papers, 1985-1987. B.100 ‘Applications for Attention August 1987 - September 1988’. folder so inscribed. Contents of Correspondence and papers, 1985-1987. B.101-B.105 ‘Completed Applications August 1987-August 1988’. Contents of folder so inscribed divided into five for ease of reference. Correspondence and papers, 1987-1988. E.P. Abraham Funds 25 E.P. Abraham Cephalosporin Fund B.106 ‘Applications for Attention August 1988 - September 1989’. folder so inscribed. Contents of Correspondenceand papers, 1988-1989. B.107-B.111 ‘Completed Applications folder so inscribed divided into five for ease of reference. September 1988 - August 1989’. Contents of Correspondence and papers, 1987-1991. B.112-B.114 GREEN COLLEGE, OXFORD 1977-1978 Contents of folder inscribed ‘Radcliffe College’ and ‘Green College’ divided into three for ease of reference. Correspondence and papers re the establishment of Green College, 1977- 1978. Green College was founded in 1979 as a postgraduate college for Oxford medicine. The proposed newcollege wasinitially referred to as Radcliffe College from its Radcliffe Observatory site. Abraham was a memberof the Radcliffe College Committee which was set up by the University to advise Council on the steps to be taken to bring the College into existence including recommendations to Council on the selection of the first Warden and Fellows. The E.P. Abraham Cephalosporin Fund made a generous benefaction to the University for the use of the new Society. The College was named Green College after its principal benefactors Dr Cecil Green, a founder of Texas Instruments and his wife Dr Ida Green. Sir Richard Doll wasthe first Warden of Green College. B.115 B.115 BARCLAYS BANK PLC 1970-1989 Miscellaneous correspondence and papers re financial administration from the Fund’s Barclays Bank files, 1970-1989. E.P. Abraham Funds 26 E.P. Abraham Cephalosporin Fund B.116, B.117 W.H. BAYLISS, SONS & CO. / KIDSONS (Chartered Accountants) 1970-1989 Correspondence and papers with the Fund’s accountants, W.H. Bayliss Sons & Co. (Kidsons from September 1987). Bayliss, Sons & Co. were the accountants for the Funds established with Cephalosporin royalties. See also A.133-A.141. B.116 1970-1978. Includes correspondence re Chief Inspector of Taxes’ enquiries re the Fund. B.117 1979-1989. B.118 MALLAM, LEWIS & NORRIS / MALLAM, LEWIS & TAYLOR (Solicitors) 1970-1989 B.118 Correspondence with the Fund’s solicitors, 1970-1989. Includes draft of Deed of Appointment of George Gow Brownlee, E.P. Abraham Professor of Chemical Pathology in the University of Oxford, as an ex officio Trustee of the Fund, 1989. B.119, B.120 NATIONAL RESEARCH DEVELOPMENTFUND / BRITISH TECHNOLOGY GROUP 1970-1987 Includes copies of the Cephalosporin Exploitation and Revenue Sharing Accounts and related correspondence. B.119 B.120 1970-1978. 1982-1987. E.P. Abraham Funds 27 E.P. Abraham Cephalosporin Fund B.121, B.122 ROBERT FLEMING INVESTMENT MANAGEMENT LTD 1978-1987 Correspondence and papers, 1978-1987. See A.148-A.153 B.121 1978-1981. B.122 1982-1987. B.123 B.123 UNIVERSITY OF OXFORD TRUSTS POOL 1971-1986 Correspondence and papers re the Fund’s Trusts Pool investments, 1971- 1986. B.124 MOVEMENT ON GRANTS 1983-1987 B.124 Annual records of ‘movement on grants’ from year ending 5 April 1984 to year ending 5 April 1987. B.125-B.132 FINANCIAL PAPERS / PAPERS FOR TRUSTEES’ MEETINGS 1976-1989 The sequence of papers includes statements of assets, commitments, donations, expenditure, investments, royalties, and minutes of a number of meetings of Trustees and meetings with representatives of Robert Fleming Investment ManagementLtd. B.125 1976-1979. B.126 1980-1981. E.P. Abraham Funds 28 E.P. Abraham Cephalosporin Fund B.127 1982. B.128 1983. B.129 1984. B.130 1985. B.131 1986. B.132 1987-1989. B.133-B.148 ACCOUNTS 1970-1986 B.133 1970. B.134 1971. B.135 1972. B.136 1973. B.137 1974. B.138 1975. B.139 1976. E.P. Abraham Cephalosporin Fund E.P. Abraham Funds B.140 1977. B.141 1978. B.142 B.143 B.144 1 January 1979-5 April 1980. Year ended 5 April 1981. Year ended 5 April 1982. B.145 Year ended 5 April 1983. B.146 Year ended 5 April 1984. B.147 Year ended 5 April 1985. B.148 Year ended 5 April 1986. E.P. Abraham Funds 30 INDEX OF CORRESPONDENTS ABRAHAM, Sir Edward Penley ACHARYA, K.Ravindra ADAMS, Christopher B.T. APLIN, Robin T. ARMITAGE, P. ASHCROFT,Frances Mary ASHCROFT,S.J.H. ASHLEY,C.C. ATKINS, F. Brian ATKINS,Peter W. AYLMER, Gerald Edward BADDILEY,Sir James BADENOCH,, Sir John BAILEY, Sydney BALDWIN, Sir Jack (Edward) BALL, Christopher J.E. A.1-A.154, B.1-B.123 B.98, B.111 A.41 B.51 A.65 A.87, A.107 A.107 B.85 B.16, B.39 A.123, B.19, B.20, B.39 B.58, B.62-B.65, B.95, B.104 B.43, B.47, B.49, B.50, B.54, B.55, B.57, B.59, B.60, B.67, B.71, B.87, B.100-B.107, B.109, B.110 B.96, B.97 B.65 A.74, A.110, B.27, B.29, B.47, B.53, B.67, B.72, B.100, B.109 A.31, A.36, A.62, A.116-A.118, A.149, B.16, B.19, B.39, B.48, B.69, B.78, B.79, B.86 BALZERS HIGH VACUUM LTD A.42 BAMBOROUGH, John Bernard BANNISTER, Sir Roger BARALLE, F.E. BARCLAYS BANK LTD BARD, Basil J.A. BEARD, Geoffrey A.53, B.4, B.11, B.15-B.17, B.44, B.55, B.62, B.72 B.94, B.97 A.39 A.4-A.6, A.132, A.134, B.115 A.2 A.119 E.P. Abraham Funds 31 Index of correspondents BENNETT,Mary (Mrs John Bennett) BENTLEY,David R. BERGEL,D.H. BERRY,R. Stephen BICKNELL, Roy BIOCHEMICAL SOCIETY BIRCH,Arthur John BJORKLUND,Anders BLAKE,Colin BLAKE, Robert Norman William, Baron BLAKEMORE, Colin Brian BLASCHKO, Hermann Karl Felix BLOCH, Konrad Emil BOE, Alf BORN, Gustav Victor Rudolf BOYD, C.A.Richard BRITISH COUNCIL BRITISH TECHNOLOGY GROUP BROCK, Hugh BROCK, Michael George BROMWICH, Peter D. BROWN, M.C. BROWNLEE, George Gow BRUNER, Jerome BURDETT,K. BURLEY,J. B.24, B.28 A.68 A.61, A.108 A.131 A.89 A.17, B.66 A.120, A.128 A.126, A.131 B.83 6.3, B.9, B.10, 8.15, B.21, B.32, B.33, B.39, B.45, B.48 A.40, A.43, A.66, A.71, A.72, A.75, A.81, A.85, A.95, B.57, B.92, B.93, B.101, B.107, B.109 H.125 A.118, A.128, A.129 B.82 B.63 A.105 A.39 A.146, A.147, B.120 A.39 A.62, B.54, B.55, B.66 A.68 A.95 A.27, A.123, A.127, A.129, B.99 B.40 A.30 A.111, A.114 E.P. Abraham Funds 32 Index of correspondents BURNETT,John H. CAIN, JamesC. CALDER, Renate, Lady CAMPBELL, R. Duncan CANCER RELIEF CASTON, Geoffrey CHADWICK,Henry CHARLTON, Harry M. CHEETHAM, Anthony Keith A.22, B.46 A.3, A.21, A.143 B.56, B.61 A.95, A.97, A.99, A.113, B.84, B.101 See NATIONAL SOCIETY FOR CANCER RELIEF A.14, A.15, A.18, A.25, A.115, B.112 A.22 B.83 A.10, A.11, A.67, A.92, A.111, B.10, B.12, B,19, B.22 CHILVER, Elizabeth Millicent B.4, B.8, B.22-B.24, B.46 CLOUGH, Gerald COHN, Zanvil A. COLES, Sharon Kay A.66 D.131 A.86, B.84 CONTEMPORARYSCIENTIFIC ARCHIVES CENTRE B.17-B.19, B.22, B.26, B.32 COOK,Colin CORNISH, Errol M. COVENEY,PeterV. COWEY,Alan COX,Brian S. CRABBE, Michael James Cardwell CRAIG, Barbara Denise CRAIG, lan W. CRANSTOUN, G.K.L. CROCKER, Paul CUELLO, A. Claudio B.109 A.32 B.83 A.11, A.32, A.48, A.50, A.77, A.100, A.104, B.40, B.93 A.88 B.103 B.7, B.15, B.16, B.24 A.23 A.54 A.108 A.24, A.62, B.62, B.88 E.P. Abraham Funds 33 Index of correspondents DAINTON, Frederick Sydney, Baron DAWES,Geoffrey Sharman DEANE, H.W. B.86 A.65 B.11 DOBSON, Christopher Martin A.86, B.85 DOBSON, Colin DOBSON,Mary DOLL,Sir (William) Richard (Shaboe) DOREY,A.J. DORRINGTON, Keith DRAGON SCHOOL, OXFORD DWEK, Raymond Allen DYKE,Keith G.H. E.R. SQUIBB & SONS, INC. EDWARDS, JohnHilton ELDERS, Christopher F. ELLORY,J.Clive ELY, Susan B.29, B.38, B.45, B.48, B.65, B.69, B.72, B.85, B.87, B.95, B.101, B.111 B.57 A.19, A.20, A.22, A.26, A.33, A.47, B.14-B.16, B.20, B.21, B.25, B.33, B.112, B.113 A.103, A.115-A.117, A.119, B.100 A.110 B.65 A.47 B.50 A.15 A.41, A.45, A.112, B.79, B.81 B.104 B.105 A.75 EMBO EUROPEAN MOLECULAR BIOLOGY LABORATORY A.56, A.77 EMSCOPE LABORATORIES LTD A.42, A.51 FAIRBROTHER, TrevorJ. FAIREY,J. Neil F. FILLENZ, Marianne FISHER, Sir Henry Arthur Pears FLEMING, Richard B.10 B.46 A.33, A.59, B.57 A.30, A.37, A.45, B.57 A.18 E.P. Abraham Funds 34 Index of correspondents FLEMING INVESTMENT MANAGEMENTLTD See ROBERT FLEMING INVESTMENT MANAGEMENT LTD FOLLETT,Sir Brian Keith FOOTE, I. Paul FRANKS, Oliver Shewell, Baron FUNG, Sek-chung FURMSTON, M.E. GARDNER, Richard Lavenham GASSER, Robert P.H. GELDER, M. GIBSON, Frank William Ernest GLASER, Gilbert H. GLAXO HOLDINGS LTD GLAZER. A. Michael GOODENOUGH, John B. GORDON, George GORDON, Siamon GOUDIE, Andrew GOULD, George N. B.109 B.59 B.33 B.63, B.69 B.3 A.43 A.27, A.28 A.46 A.129 B.40 B.117 A.36, A.46, A.49 A.22, A.91, A.100 A.95 A.20, A.25, A.27, A.30, A.36, A.97, A.102, A.108, A.119 A.83 B.45, B.48, G.65 GOWING, Margaret Mary B.17, B.19, B.26, B.32, B.99 GRAHAM, Christopher Forbes GREEN, Louise F.B. GREEN, Vivian Hubert Howard GREENFIELD, Susan Adele GUILLERY, Rainer Walter HABBAKKUK, Hrothgar John HALL, Andrew A.40, A.93 B.45 A.84, A.89, A.90 A.81 A.77, A.106, A.109, A.129, A.130 A.14, A.16, A.28 B.101 E.P. Abraham Funds 35 Index of correspondents HALL, G. Derek G. HALSALL,T.G. HARLEY,John Laker HARRE, Rom HARRIS, Sir Henry HAWES, C.R. HAYTER, Sir William Goodenough HELMAN, Marc HENDRY,Bruce HEYWOOD,Peter HILL, Hugh Allen Oliver HINKS, F. Paul HIRSCH, Sir Peter Bernhard HODGKIN, Sir Alan Lloyd HOLLAND, Peter HOLT, J.M. HOOGWERF,Anna Marie HORSLEY,W.T. HUDSON, T.A.D. CADOUX- HUGHES, J.F. HUI, Suk-wai HUMPHREY,John Herbert HUNT,Simon V. HUXLEY,Sir Andrew Fielding A.6 B.22 A.22 B.108 A.12-A.19, A.23-A.25, A.28, A.30- A.32, A.35, A.38, A.40, A.43, A.45, A.47, A.52, A.61, A.63, A.65, A.69, A.72, A.78, A.89, A.95, A.97, A.98, A.106, A.113, A.136 B.110 B.16 B.104 B.108 B.69 A.23, B.50 A.139, A.150, A.151 A.112 B.12 A.110 B.14 A.39 B.19 B.95 A.38 B.86 B.83 A.97, A.110, B.67 B.60 See also A.49 INLAND REVENUE A.3, A.136, A.137, A.141, B.116 E.P. Abraham Funds 36 Index of correspondents JACK,Julian J.B. JACOBS, Margaret JAMES, William S. JENSON, Bent JUEL- JOHN RADCLIFFE HOSPITAL JOHNSON, Louise Napier JONES,Sir Ewart Ray Herbert (‘Tim’) A.35 B.26 A.110 B.96 A.78 A.104 A.22, B.4, B.7-B.11, B.13, B.16, B.20-B.22, B.26 JUNIPER, Barrie E. A.51, A.83, B.78 KAY, Desmond KAY, R.H. KEARSEY,Stephen E. KEITH, Ronald Mac KEMP, T.S. KENNER, George Wallace A.101 A.29, A.107 B.108, B.110 A.9, B.7, B.15, B.18, B.19 B.16, B.17 B.1-B.4, B.7-B.21, B.23-B.27, B.29- B.33, B.35, B.118 KENNY, Anthony John Patrick KEYMER, AnneE. B.60 B.75 KIDSONS, Chartered Accountants A.141, A.153 KIERNAN, C.C. KING, Andrew J. KING, Glenn F. KING EDWARD VI SCHOOL SOUTHAMPTON KINGSMAN, Susan M. KJELLSTRAND, Carl M. KNOWLES, Jeremy Randall KORNBERG, Sir Hans Leo B.40 B.104 B.99 B.29, B.38, B.45, B.48, B.65, B.69, B.72, B.85, B.87, B.95, B.101, B.111 B.80 B.30 A.120, A.129, B.10 A.50, B.53, B.56, B.61, B.66 E.P. Abraham Funds 37 Index of correspondents KREBS,Sir John Richard LANKESTER, J. LAWS, G.C. LITTLE, David J. LOWE, Gordon McCRUDDEN, John C. MacDERMOTT,Alexandra McDONALD, Alison W. McDOWELL,lan F.W. McGEE, JamesO.’D. MacKINNON, Pamela C.B. MACNAUGHTON, Sir Malcolm MacPHERSON, Gordon G. MADDISON, Francis MALLAM, LEWIS & NORRIS, Solicitors MALLAM, LEWIS & TAYLOR, Solicitors MATTHEWS, Margaret MATTHEWS,W.B. B.94 A.70 B.3, B.7 A.76 A.9, A.94, A.107, B.93 B.68 B.76 B.100 A.40 A.78 A.37, A.47, A.60 A.98 A.68 B.2 A.1, A.2, A.3, A.12, A.13, A.15, A.16, A.33, A.34, A.52, A.133, A.137-A.139, B.1-B.3, B.7, B.13, B.29, B.31, B.33, B.43, B.51, B.62, B.118 See MALLAM, LEWIS & NORRIS, Solicitors B.101 B.41 MEDICAL RESEARCH COUNCIL A.44, A.92, A.93 MRC LABORATORY ANIMALS CENTRE A.66 MELLANBY,Jane MILLER, A. MILSTEIN, Jerrold M. MITCHELL,Basil G. MITCHELL, R.G. A.24, B.23 B.88 B.17 A.52 B.33 E.P. Abraham Funds 38 Index of correspondents MITCHELL, R.G. MOKOENA, Taole MOORE, David R. MOORE, Mary (Mrs A.R. Moore) MORRELL, PEEL & GAMLEN,Solicitors MORRIS,PeterJ. MORRISSEY,James H. MORTIMER, Maurice JONES- MOSER,Sir Claus Adolf MOXON, E.Richard NATIONAL FILM SCHOOL B.33 A.97 A.84 B.51, B.54, B.55, B.57, B.62, B.73, B.74 B.29 A.28 A.56 B.47, B.61 B.82, B.87 A.75, A.88 B.41, B.42 NATIONAL RESEARCH DEVELOPMENT CORPORATION A.2-A.5, A.21, A.142-A.147, A.191, B.55, B.119 NATIONAL SOCIETY FOR CANCER RELIEF SOBELL HOUSE APPEAL NEILL, Sir Patrick NEWCOMBE,Freda NEWELL,PeterC. NEWSHOLME, Eric A. NEWTON, Rosemary NORTH, J.D. NYE, Piers C.G. OAKESHOTT, Sir Walter Fraser O’CONNOR, N.O. ODOOM, Joseph E. OGSTON, Alexander George A.41, B.57 B.93 B.40-B.42 A.56, B.102 A.35, A.105, A.113, B.95-B.97 A.117 B.1, B.2 A.66, B.107, B.109 A.2-A.6, A.8, A.9, B.1, B.3, B.7, B.29 Seealso A.7 B.40 B.105 A.16 E.P. Abraham Funds 39 Index of correspondents OSBORNE, Neville N. OWENS, S.J. OXFORD ARCHITECTS PARTNERSHIP OXFORD INSTRUMENTS GROUP LTD A.99, B.98 B.107 A.119 A.97 OXFORD UNIVERSITY See UNIVERSITY OF OXFORD OXFORD UNIVERSITY SCIENTIFIC SOCIETY A.121 OXFORDSHIRE AREA HEALTH AUTHORITY A.63, B.33, B.37, B.40-B.42, B.95 PALLEY,Claire PALSDOTTIR, Astridur B.94 B.85 PARK, Daphne Margaret Sybil Désirée, Baroness A.60, B.69 PARKER, Sir Peter B.70, B.89, B.91, B.96 PATON, Sir William Drummond Macdonald A.38, A.118, A.120, B.2, B.18 PATTERSON, T.J.S. PAYNE, lan R. PEARCE, Christopher PELLING, Margaret PERRY,David PHILLIPS, C.S.G. PHILLIPS, Charles Garrett PHILLIPS, David Chilton, Baron POLYTECHNIC OF CENTRAL LONDON POORE, M.E.Duncan PORTER, Rodney Robert PORTERFIELD, JamesS. PRIESTLEY,J.V. PRINGLE, John William Sutton B.37, B.51 A.153 B.25 B.37 A.112 A.100, A.101 A.27, A.33, A.55, A.61, B.34, B.39, B.45, B.72 A.23, A.31, A.42, A.43, B.36, B.46, B.61, B.75, B.77, B.83 A.112 A.34, A.58 A.18, A.21, A.70. A.124, B.57, B.67 A.23, A.39, A.62 See also A.102 B.62 A.22, A.42 E.P. Abraham Funds 40 Index of correspondents PROUT, C. Keith PUGH, Christopher PYE UNICAM LTD RABINOWITZ, Stephen RADCLIFFE INFIRMARY, OXFORD DEPARTMENT OF NEUROSURGERY RADDA,Sir George Karoly RANDLE, Sir Philip John REDMAN, C.W.G. REID, H. Alistair REID, Kenneth B.M. RICHARDS, Sir Rex Edward B.62 A.41 A.42 A.102 A.41 A.45 A.121 A.79 A.5 A.97, A.109 A.69, A.97 See also A.120 ROBERT FLEMING & CO. LTD A.4-A.6, A.148, A.152 ROBERT FLEMING INVESTMENT MANAGEMENTLTD ROBERTS, David B. ROBERTS, John ROBERTS, John Alexander Fraser ROBERTS, John Morris ROBINSON, Anne ROBINSON, Michael J.T RODERIGUES,Nanda ROGERS, D.G. Fletcher ROSEN, Hugh ROWLINSON, Sir John Shipley ROYAL COLLEGE OF GENERAL PRACTITIONERS ROYAL COLLEGE OF OBSTETRICIANS AND GYNAECOLOGISTS A.90, A.139, A.141, A.149-A.153, B.121, B.122 A.31, A.102, A.113, B.77 A.19 B.21 B.81 A.68 B.30, B.39 B.101 A.3 A.108 A.22, A.69 A.48 A.98 E.P. Abraham Funds 41 Index of correspondents ROYAL SOCIETY A.11, B.1, B.2, B.9, B.11, B.13, B.25, B.39, B.46, B.48-B.51, B.53, B.61, B.64, B.69, B.78, B.85, B.86, B.96, B.102, B.109-B.111 RYAN, Terence J. A.63, A.96, A.111 SABATH, Leon David (‘Lee’) SANDFORD, Sir Folliott SCIENCE RESEARCH COUNCIL SEMPER, A.E. SHARPE, Bryan Percy Kenneth SHAW, Dennis SHEAVES, Richard SHEPPARD, Colin J.R. SHERMAN, S. Murray SHIA, Gilbert T.W. SHOCK, Sir Maurice SHOTTON, David M. SIDEBOTTOM, Eric SINGER, S. Jon(athan) SLACK,Mary P. E. SMITH, Anthony David SMITH, Sir David Cecil SMITH, David Spencer SOCIETY FOR THE PROTECTION OF SCIENCE AND LEARNING LTD SOUTHERN, Edwin Mellor B.1-B.4, B.7-B.27, B.29-B.33, B.35, B.40, B.43, B.47, B.50, B.54, B.55, B.57, B.58, B.59, B.87, B.100, B.101, B.106 A.1, A.3, A.8 A.32 B.105 A.91 B.93, B.96 B.84 A.48 A.124, A.129, A.130 A.43, A.44, A.64 A.107, A.110, A.141 A.77, A.98, B.74, B.86, B.96, B.102, B.105 A.22, A.33, A.36, B.94 A.124, A.129 A.62, A.99 A.85, A.92, A.126, B.77, B.83 A.50, B.69 B.102 B.83 A.93, A.105 E.P. Abraham Funds 42 Index of correspondents SOUTHWOOD,Sir (Thomas) Richard (Edmund) SPRATT, Brian G. STAFFORD, Godfrey Harry STEIN, John F. STEWART, Duncan STIRRAT, Gordon M. STUART,David STUART, J. BURNETT- SUTHERLAND,DameLucyStuart SUTTON, Leslie Ernest SWORD, Richard W. SYKES, M.K. TARKOWSKI, A.K. TAYLOR, Ann THOMPSON, I.D. THOMSON, Alex M. TIZARD, Sir (John) Peter (Mills) TODD, Rosemary J. TOESCU, Emil-Crisan TOMITA, Tadao TOOZE, John TRENAMAN, Nancy (Mrs M.S. Trenaman) TREND, Burke St John, Baron TRICKETT, Rachel A.37, A.40, A.110, A.114, B.73, B.96, B.108 See also A.106 B.49 A.60, A.114, B.69, B.78, B.95 A.87 B.67, B.69, B.73 A.32 A.104, B.98 A.149-A.153 B.3 B.9, B.30 B.56 A.82 A.93 A.75 A.59, B.81 A.71, A.72 B.56, B.57 B.98 A.109 D.131 A.56, A.77 B.44, B.48 A.10-A.17, A.19, A.21, A.25, A.27, A.30, A.33, A.40, A.41, A.43, A.44, A.48, A.52, A.70, A.74, A.89, A.90, A.103, A.116, A.121, A.135, A.138, A.145, A.146, A.148, A.149, B.10, B.23, B.31, B.39, B.56 See also A.128 B.28, B.61, B.65, B.74, B.87 E.P. Abraham Funds 43 Index of correspondents TURNBULL,Alec C. TURNER, Christopher E. TURNER, David Warren UNIVERSITY OF OXFORD BALLIOL COLLEGE CHRIST CHURCH GREEN COLLEGE EXETER COLLEGE KEBLE COLLEGE LADY MARGARET HALL LINACRE COLLEGE LINCOLN COLLEGE MERTON COLLEGE NUFFIELD COLLEGE THE QUEEN’S COLLEGE PEMBROKE COLLEGE ST ANNE’S COLLEGE A.40, A.58, A.62, A.68, A.76, A.79, A.98 A.77 A.25 A.49, A.113, B.60 A.31 A.33, A.47, B.80, B.87, B.96, B.108, B.112-B.114 A.19, A.20, B.57 A.31, A.36, A.62, B.48, B.69, B.79, B.83 A.58, A.89, A.100, B.3, B.4, B.7, B.8, B.22-B.24, B.46, B.67, B.69, B.73, B.78, B.97 A.33, A.53, A.78, B.4, B.11, B.15- B.17, B.44, B.55, B.62, B.72, B.108 A.2, A.3, A.5, A.6, A.8, A.10-A.17, A.21, A.22, A.25, A.27, A.33, A.41, A.43, A.44, A.48, A.52, A.60, A.74, A.84, A.89, A.107, A.110, A.116- A.118, A.120, A.135, A.141, A.149, A.191, B.3, B.5, B.7, B.10, B.16, B.19, B.23, B.39, B.56, B.68, B.86 See also A.128 A.19, A.113, B.95, B.96 A.62, B.54, B.55, B.57, B.66 B.3, B.7, B.9, B.10, B.15, B.18, B.21, B.32, B.39, B.45, B.48, B.59 See also B.6 B.94, B.97 B.44, B.48, B.94 ST CATHERINE’S COLLEGE A.23 ST CROSS COLLEGE A.60, A.114, B.69, B.96 E.P. Abraham Funds 44 Index of correspondents UNIVERSITY OF OXFORD CONT’D ST HILDA’S COLLEGE ST HUGH’S COLLEGE ST PETER’S COLLEGE SOMERVILLE COLLEGE TRINITY COLLEGE WADHAM COLLEGE WOLFSON COLLEGE BOTANY SCHOOL CHEMICAL CRYSTALLOGRAPHY LABORATORY B.24, B.28, B.29, B.51, B.54, B.55, B.57, B.64, B.73, B.74, B.75 A.50, B.26, B.28, B.39, B.61, B.65, B.74, B.87 B.58, B.62-B.65, B.95, B.99, B.104 A.60, B.7, B.15, B.16, B.25, B.69 A.16, A.17, A.19 A.17, B.82, B.87 A.30, A.37, A.45, A.64, A.91, A.104, B.57, B.63, B.103 A.19, A.23, A.30, A.51, A.83, B.56, B.78 A.67, A.92, A.111, A.191, B.62 DEPARTMENT OF AGRICULTURAL AND FOREST SCIENCES A.34, A.38, A.50, A.58 DEPARTMENT OF BIOCHEMISTRY GENETICS LABORATORY MRC IMMUNOCHEMISTRYUNIT A.21, A.31, A.36, A.45, A.47, A.56, A.86, A.93, A.102, A.105, A.109, A.113, B.57, B.67, B.80, B.83, B.85, B.88, B.99, B.102, B.103, B.108, B.111 A.31, A.39, A.41, A.45, A.102, A.112, A.113, B.77, B.79, B.81 A.95, A.97, A.99, A.109, A.113, B.84 MICROBIOLOGY UNIT DEPARTMENT OF BIOMATHEMATICS DEPARTMENTOF CLINICAL NEUROLOGY B.50 A.65 B.41 DEPARTMENT OF DERMATOLOGY A.63, A.96, A.111 DEPARTMENT OF EARTH SCIENCES DEPARTMENT OF ENGINEERING SCIENCE B.104 A.48 DEPARTMENT OF EXPERIMENTAL PSYCHOLOGY A.32, A.48, A.50, A.58, A.68, A.77, A.81, A.100, A.104, B.23, B.93 E.P. Abraham Funds 45 Index of correspondents UNIVERSITY OF OXFORD CONT’D DEPARTMENT OF GEOLOGY AND MINERALOGY A.45, A.64 DEPARTMENT OF HUMAN ANATOMY A.27, A.33, A.37, A.55, A.60, A.61, A.77, A.105, A.106, A.109, A.129, A.130, B.18, B.34, B.39, B.45, B.62, B.83, B.101 DEPARTMENT OF INORGANIC CHEMISTRY A.10, A.16, A.23, A.54 DEPARTMENT OF METALLURGY AND SCIENCE OF MATERIALS A.112 DEPARTMENT OF PAEDIATRICS A.62, A.75, A.88, B.56, B.57 DEPARTMENT OF PATHOLOGY A.78 DEPARTMENTOF PHYSICS DEPARTMENT OF PLANT SCIENCES A.36, A.46, A.49 A.88, A.111, B.110 OXFORD FORESTRY INSTITUTE A.111, A.114, B.100 DEPARTMENT OF PSYCHIATRY A.46 DEPARTMENT OF ZOOLOGY A.37, A.40, A.41, A.42, A.77, A.86, A.93, A.98, A.110, A.114, B.45, B.73-B.75, B.84, B.86, B.96, B.102, B.105, B.107, B.108, B.110 See also A.106 LABORATORY OF MOLECULAR BIOPHYSICS A.23, A.43, A.104, B.72, B.75, B.77, B.83, B.98 DYSON PERRINS LABORATORY INORGANIC CHEMISTRY LABORATORY A.9, A.57, A.74, A.94, A.107, A.110, A.122, A.123, A.128, B.4, B.7-B.11, B.13, B.16, B.20-B.22, B.26, B.30, B.39, B.47, B.51, B.53, B.67, B.72, B.93, B.109 A.23, A.30, A.54, A.86, A.91, A.92, A.99, A.101, A.102, B.85 NUFFIELD DEPARTMENT OF ANAESTHETICS NUFFIELD DEPARTMENTOF CLINICAL BIOCHEMISTRY A.82 A.107 NUFFIELD DEPARTMENTOF CLINICAL MEDICINE A.30, B.108 NUFFIELD DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY A.32, A.40, A.58, A.62, A.68, A.76, A.79, A.98 NUFFIELD DEPARTMENT OF PATHOLOGY A.62, A.99, A.101 E.P. Abraham Funds 46 Index of correspondents UNIVERSITY OF OXFORD CONT’D NUFFIELD INSTITUTE FOR MEDICAL RESEARCH A.65 NUFFIELD LABORATORY OF OPHTHALMOLOGY A.99, B.98 PHYSICAL CHEMISTRY LABORATORY SCHOOL OF GEOGRAPHY A.69, B.76 A.83 SIR WILLIAM DUNN SCHOOL OF PATHOLOGY A.8-A.11, A.15, A.16, A.20, A.28, A.33, A.34, A.36, A.39, A.43, A.44, A.57, A.59, A.62, A.68, A.80, A.84, A.85, A.89, A.95, A.97, A.100- A.102, A.104, A.106-A.108, A.110, A.191, B.67, B.99, B.108 MRC CELLULAR IMMUNOLOGY UNIT A.48 UNIVERSITY DEPARTMENT OF PHARMACOLOGY A.24, A.38, A.62, A.85, A.92, A.107, B.62, B.77, B.83, B.86, B.88 MRC ANATOMICAL NEURO- PHARMACOLOGY UNIT A.107, A.110 UNIVERSITY LABORATORY OF PHYSIOLOGY A.33, A.35, A.39, A.40, A.43, A.59, A.61, A.62, A.66, A.71-A.73, A.75, A.81, A.84, A.85, A.87, A.95, A.107, A.108, B.57, B.63, B.66, B.69, B.76, B.77, B.81, B.85, B.92, B.93, B.101, B.104, B.105, B.107, B.109 MUSEUM OF THE HISTORY OF SCIENCE B.1, B.2 HOOKE LIBRARY APPEAL RADCLIFFE SCIENCE LIBRARY B.96 B.93 WELLCOME UNIT FOR THE HISTORY OF MEDICINE B.37, B.51, B.54, B.58 ACCOMMODATION OFFICE A.12 UNIVERSITY CHEST UNIVERSITY MUSEUM UNIVERSITY OFFICES A.6, A.7, A.9, A.14, A.134, A.154, B.4, B.123 B.16 A.18, A.20, A.22, A.25, A.27, A.28, A.45, A.65, A.69, A.70, A.93, A.99, A.103, A.106, A.114, A.115-A.131, A.135, A.139, A.154, A.191, B.17, B.19, B.93, B.94, B.112-B.114 UNIVERSITY PRESS A.11 E.P. Abraham Funds 47 Index of correspondents UNIVERSITY OF OXFORD CONT’D UNIVERSITY REGISTRY A.1, A.3, A.8, A.14, A.15 UNIVERSITY SURVEYOR’S OFFICE A.41, A.59, A.65, A.69, A.70, A.93, A.95, A.106, A.112, B.16, B.72 VINCENT, Ewart Albert VOLLRATH, Fritz VONDERHEIDE, Robert H. A.64 B.108 A.110 W.M. BAYLISS, SONS & CO., Chartered Accountants WADMAN, Meredith WALEY,Stephen G. A.2, A.4-A.6, A.133-A.141, A.151, A.152, B.116, B.117 A.103 A.68, A.80, A.84, A.85, A.95, A.100, A.104, A.106, A.108 WALTON, John Nicholas, Baron B.80, B.87, B.96, B.108, B.110 WARNER, Francis WARNOCK,Sir Geoffrey James WATKINSON, Sarah WATTS,Anthony WEATHERALL,Sir David John WEBSTER, Charles WEDDELL,A. Graham M. WELLCOME TRUST B.99 A.45, A.70 B.29, B.51, B.56, B.64 A.36, A.86, B.83, B.88, B.103, B.111 A.30, A.118, B.108 B.10, B.37, B.58 B.18 A.26, A.32 WHATLEY,Frederick Robert A.19, A.22, A.23, A.30, A.45 WHITE, John W. WHITTEN, Max J. WHITTERIDGE, David WILLIAMS,Alan F. WILLIAMS,Rachel B.51 A.114 A.27, A.58, A.62, A.68, A.81, A.107, A.110, B.34 A.48 B.78 E.P. Abraham Funds 48 Index of correspondents WILLIAMS, Robert John Paton WILLIAMS, Trevor Illtyd WYLIE, John A.H. ~ YOUNG, Geoffrey T. YU Chack-Yung YUDKIN, Michael David A.30, A.92, A.102 See also A.34 B.92 A.15, A.16 B.47 A.99, B.84 B.16 See also B.14