THE ROYAL COMMISSION ON HISTORICAL MANUSCRIPTS
Report on the papers of
BSGTR ALD
-8.E:3.P-3EN
SS PAC EY
professor of pharamacology and therapeutics
1905-1974
THE ROYAL COMMISSION ON HISTORICAL MANUSCRIPTS
London WC2A 1HP
Archives Centre
(CSAC 22/16/74)
b y
Reproduced for the Contemporary Scientific
Quality House, Quality Court, Chancery Lane,
No. 75/1
1975
All rights reserved
THE ROYAL SOCIETY
THE ROYAL COMMISSION ON HISTORICAL
MANUSCRIPTS
Committee on Scientific and Technological Records
csac
22/16/74
CONTEMPORARY SCIENTIFIC ARCHIVES CENTRE
Papers of
Reginald Stephen Stacey
(1905 — 1974)
Deposited in the University of London Library
1974
Listed by: Jearinine Alton
Harriot Weiskittel
R.S.S.
C.S.A.C.
22/16/74
Description of the collection.
Wellcome Research Laboratories, Beckenham.
The papers were received from Mrs. Helen Stacey,and the
The collection consists almost entirely of work at St. Thomas's
— 57 are his laboratory notebooks and experimental
Hospital,London,where Stacey was Reader and later Professor of Pharmacology
and Therapeutics. Items 4
observations on brain amines and blood—platelets,including data for his
work on amine metabolism in suicides,neonates and mental defectives.
Items 70 — 72,97 - 177 are notes for lectures,demonstrations,curricula and
examinations for St. Thomas's Hospital and the University of London, which
give information on the organisation and development of courses of study in
Pharmacology and Therapeutics.
or descriptions in inverted commas are those which appear on the ISS.
Unless otherwise stated,all material is manuscript. Titles
Summary of the career of R.S.Stacey
1905
b. London
educ. Haberdashers' Aske's School
1924 = 27
Trinity College,Cambridge (Scholar); Physiology Cl.I
University of Vienna
1970 = 74
University of Oxford
married Helen Duke
1927
1927 = 30
1935 - 47
1933
married Margery North
1947 — 48
1948 ~ 58
1951
1958 — 70
1963 = 70
St. Thomas's Hospital Medical School; B.Chir. 1930
Reader in Pharmacology & Therapeutics,St. Thomas's Hospital
1932, — 35
First Assistant to Professor of Medicine,St. Thomas's
Professor of Pharmacology & Therapeutics,Royal College of Medicine,
Baghdad
Wellcome Research Laboratories, Beckenham.
first holder of Chair in Pharmacology & Therapeutics,University
of London
Professor of Pharmacology & Therapeutics,St. Thomas's Hospital
RiSeS.
Casket. 2 22/16/74
Contents of the handlist
Biographical
Laboratory Notebooks
Working papers
5—-HT and MAO
Platelets
Brain Amines
Misc. drugs
12
27
33
40
Publications
"
Lectures & Demonstrations
"
"
Conferences
Committees and Societies
Correspondence
58 — 61
181 — 183
62 = 72
97 =— 173
13 - 74
75 = 80
81
= 96
University of London etc.
174 =- 180
Index of principal correspondents
Biographical Material.
Laboratory Notebooks.
4 -
1931
1956 — 67
Photographs of Stacey and colleagues: c.1932 — 35, and 1968
Obituary notices: Lancet,March 2,1974(by Steven E. Smith);BMJ,March 2, 1974
Notebook,mainly pharmacological testing methods, indexed
front and rear.(Probably kept by Stacey while resident House
Physician,St. Thomas's Hospital Medical School).
Continued...
11 Notebooks of experiments,observations and research as Reader
(later Professor) of Pharmacology & Therapeutics,St. Thomas's.
All the books have numbered pages and indexes by Stacey, Book
A (no.4, below) at rear, all others at front.
ok
be
Book B
5.
Book.C.
6,
Book D
7.
Book
BE
8.
9.
Book F
10. Book G@
11s Book -&
13.XI.56 = 25.V1I.58
24,VI.58 — 29.11.60
2.11.60 — 15.191.61
15,111.61 -12.V1.62
20.III.62— 21.X.63
13.VI.62 = 1.III.65
4.11.63 —
29.1X.66
8, IIT.65: =°3 211.67
12.
‘H.T.'3 expts.case-notes,correspondence,lMs. draft of paper
1955 = 60
Professor Stacey's ordering and description of the notes have been
preserved; some files include related offprints and correspondence.
III.
Working papers.
ReS.Ss CeseA.C. 22/16/74
12.
continued
*Red cells and 5-HT'; correspondence 1955 — 57 with Dr. W.
Jacobson.
Tryptamine; notes and charts,some dated 1963.
Tryptamine; notes,charts,calculns.;Ms.draft for paper
(untitled) on platelets.
Tryptamine; expts. and notes.
'MAO Estimations'; notes and expts.
'}IAO Estimationst; notes and expts.; text of short
communication "Monoamine Oxydase activity of platelets!
(Latt,Rippey Stacey).
26 Work on 5-HT (5-Hydroxy—tryptamine)
‘HTP Experimental'; expts.,tables and notes; includes Ms.
paper ‘Observations on the Synthesis and Storage of 5-HT by
small intestine, B.Pharmacol.Soc. Jan.1953 Barts.'
Casenotes,expts.etc. on 5-dT; includes correspondence with
Roger Hardisty and draft of his paper on Thromasthenia.
1957
1961
'S-HT Absorption'sexpts. and tests by Stacey and collaborators, 1960
numbered and dated.
1961
1963
1964
Ditto
Ditto
Ditto
Figures and tables on 5-HT,Perh. for paper.
'Neonates and Infants. Blood'; tests and expts. on 5—-HT in
umbilical cord,and infants’ blood.
'Notes 5-Hydroxytryptamine'; misc. notes on books and
articles read; expts.and observations; charts; Ms. draft
of article (untitled) on history and present. state of work
on 5-HT (8 pp.)
Tiss
'Platelet Fractionation'; expts.,charts,calculns.
"Platelets
numbered and dated by Stacey and collaborators.
145 tryptamine 1
— 199'; expts. and case-notes,
Misc. notes and correspondence on platelets.
'Platelet Gradient Expts.'
32 Work on Platelets.
Ditto
200 — 305.
C.S.A.C.
22/16/74
A.
"Platelet Experiments'; misc. notes, sraphs and working papers, 1955
variously dated 1955 = 60,end lis. drafts for
5-HT in platelets. (one for Mxperientia, 1963)
communications on
39 Work on Brain Amines.
"Brain Amines. Suicides.'; case-notes,tests and expt. calculns, 1967
numbered by Stacey and collaborators 1
(not all in numerical sequence).
— 51.
‘Brain Amines. Bevan Jones,Pare,Stacey'; ditto,numbered
1
— 52.
"Brain Amines Human'; notes and expt.observations,with
correspondence and drafts for papers,with C.lichael B.Pare,
K.F.Gey.
Corrected drafts for paper,'Brain Amine Concentration after
M.A.O.I.Administration',Bevan Jones,Pare et eal.
"ISO &
expt.observations; correspondence with C.Michael B.Pare.
and Nialamide) ; notes,charts,
NIAL (Isocarboxazid
"Mental Defective Experimental'; case=-notes etc.
"Histidinuria'; case-notes,etc.
"Lactate Dehydrogenase’; case—notes etc.
1969
1969
1963
1967
1969
1969
Foetus.
5-HT in man.
Hypotensive drugs.
Cocaine and Pheochromocytoma.
Folic acids; with expts. ,notes, bibliographies,correspondence.
Uterus; includes Correspondence on leaves of West African tree
Spondias monbin L in obstetrics, i952.
57 Shorter working papers on drugs and their effects,with related
offprints, bibliographies and correspondence.
(Headings are those used by Stacey).
Parkinsonisn.
Nutmeg; includes notes for mestionand answer interview,perh. on radio.
Reserpine; includes correspondence with Roussel Laboratories 1959
Autonomic
Biogenic Amines.
Nicotine.
C.S.A.C. 22/16/74
Carcinoids.
Substance P.
Smooth muscle contracting substances.
Synoptic transmission in the spinal cord.
Enzymes,Oriental drugs, Anti-convulsants; includes catalogue of
'tIndigenous drugs of Iraq and Iran',and correspondence with Rona
laboratories 1961.
Catecholamines and MAO with related offprints,expt.data and
correspondence with May & Baker Ltd.
1969.
Iv.
Publications. See also p.11,nos.181 — 183
58.
'Platelet Function Tests in Thrombocythaemia and Thrombocytosis',
by P.D.McClure,G.I.C.Ingram,R.S.Stacey et al, Brit.J. Haemat.1966
Expt .data,observations,charts etc.; drafts and corrections for
paper}; correspondence with collaborators.
1963
‘SUICIDES! (project on brain amine levels in depression)
Published as '5-Hydroxytryptamine ,noradrenaline,and dopemine
in the brain stem,hypothalamus,and caudate nucleus of controls
and patients committing suicide by coal gas poisoning! by
C.M.B.Pare,D.P.H.Young,Kathleen Price,R.S.Stacey.
(c)1970
60.
62.
V.__
Lectures. See also pp.8 = 10,nos.97 = 173
61. "Recent Advances in Pharmacology',by J.M.Robson & R.S.Stacey,
Case-notes,expt.data,charts etc.; drafts and corrections for
paper; correspondence with collaborators.
1966
Third ed.1962,4th.ed.1965.
Correspondence with contributors and publishers.
Ms. draft for paper or article on platelets,effects of drugs,
with tables. (unpublished)
‘Mental Defectives'
Ms. lecture on Phenylketonuria given at Maudsley Hospital,
May 1959. 7pp.; with offprints,bibliographies and working
notes.
Notes,offprints,3 Ms. lectures, i3pp.7pp.6pp.
Ms. drafts and notes for leture on platelets,at Royal Society
of Medicine 1959,Barking 1971; others undated.
de
cine and the Malignant Carcinoid Syndrome
'; notes for lecture. 3pp.
Misc. Ms. drafts forlectures and slides on platelets.
'S-HT in Medi
Mosul 25.V.64
'5-HT in Disease’; notes for lecture
5pp.
Iatrogenic Diseases
Res.
67.
Se
CUS cASG.
22/16/74
Misc. notes and lectures
1.*Questions for Old Students' Day 11 Nov.1966!
2.'Braimbridge 13.11.67"; misc.notes on drugs.
3.'Observations on phenylketonuria and other forms of
mental defiency'.Ms. lecture 6pp.
"Some Clinical Aspects of 5—Hydroxytryptamine'; lecture
given at Helsinki Symposium; typescript with Ms. corrections
and additions.
see also Item 74.
‘Platelets.';address given at University College,London ; ls
notes and plan,typescript of address.
Misc. lectures at St. Thomas's
1.*Preliminary Neurology Course 23 June 1967' 6pp.
2.'Prelim Combined Neurology Course May 1970' 5pp.
3.'Drugs modifying As — Ab reactions. STH Pharmacists
18,III.70' 7pp.
Two lectures for Nurses
1955 - 57
1.'The naming of Drugs. Charge Nurse Study Day October
1955* 6pp.
2.'Drugs affecting blood pressure.Charge Nurses Jan 1957" 2pp.
'urses' Lectures!
10 Ms. lectures indexed by Stacey
1960 — 67
VI.
136
1967
Symposium on the Biological Role of Indole Derivatives,
held 10
Colombia University,New York.
(includes Stacey's report on Session B.)
12 May 1967 at College of Surgeons and Physicians,
—
Conferences.
Hypotensive drugs (2),Nov. 1960,Jan. 1967
Diuretics Jan.1967
Chemotherapy April 1961 etc.
General Pharmacology April 1961
Corticosteroids and Corticotrophin Sept. 1966
Cardiac Drugs h.d.
Hypnotics Sedatives Analgesics n.d.
Drugs used in the treatment of mental disease 3.VII.64
Chemotherapy and Malignant Disease n.d.
e
Symposium on 5—Hydroxytryptamine,held 29 — 30 llarch 1963 a
+
G
Helsinki; correspondence with Professor Iiatti K.Pe2sonen re
Stacey's journey to Helsinki and his paper "Some Clinical
Aspects of 5-liT'slis. amd correeted proof of Deper, published
in Ann.iied.,exp.Fenn,1960,46. See also Item 68,
GSS. A.C... 22/16/74
VII. Committees-and Societie
Only documents directly relating to Stacey's contribution t+
bodies have been retained.
British Journal of Pharmacology
75.
(Stacey served as Secretary to the sditorial Board Jan.1966 —
Jan. 1971)
Notes on circulation of journal,financial statements,statistics
of journal subscriptions,distribution of articles,comparative
costs etc; includes some correspondence with colleagues.
British National Committee for Physiological Sciences.
Misc. correspondence and reports re travel granits,membership
of international organisations etc.} includes Stacey's note
of proceedings at meeting 1970 on application of IUPHAR (Int.
Union Pharmacologists) to join ICSO (Int. Comn.Sdientific Organisations).
British Pharmacological Society (Committee)
1971 - 72
Report on Training of Overseas Graduates in Pharmacology, by
Steven E.Smith,prepared for Brit.J.Pharmacol.
Correspondence and notes re Joint Committee Royal Society &
Brit.Pharmacol.Soc. to administer travel fund for 5th International
Pharmacological Congress,San Francisco.
British Pharmacopoeia Commission
1963
Research Defence Society
anch, British Association, i971.
Committee I;
colleagues.
on Medicine and Doses; correspondence with
Society for Drug Research.
PD 66
Mise. correspondence} I's. note of proceedings at meeting 23.1X.66.
7
(Stacey served on the Council of the Society)
llise. correspondence; notes for talk at Sevenoaks to Junior
1957
The letters are arranged chronologically; names of correspondents
appear in the general index.
Papers and correspondence re Stacey's expert's Report in
Regina v.Anthony William John Stephenson and Terrence Brown.
8490 General professional and scientific correspondence.
Academic Correspondence;with Arnold S.V.Burgen 1963,
JeBeGllis Baker 1972
84.
85.
1951 = 56
VIII.Correspondence.
Invitetions to lecture
1967
R.S.S.
C.S.AC. 22/16/74
1959 -
61
1962 — 68
1969 = 72
Correspondence and reports on research carried out with
M.S.E. refrigerated centrifuge provided by Royal Society
Grant—in-aid.
Mise correspondence with pharmaceutical suppliers on
analgesic drugs.
96. Work as examiner,referee etc. Restricted
87.
88.
89.
90.
at.
Lectures, Demonstrations etc.
(see also nos. 62 — 72)
The lectures were frequently updated by corrections,deletions,and insertions
of new material or references.
Misc. Lectures on Therapeutics.
976
‘Chemotherapy’; notes for lectures on chemical structure and
properties of Sulphonomides,Penicillins,Streptomycin, polypeptide
antobiotics etc.
98.
"Cardiovascular System!
104.
105,106.
107
108.
109.
"Therapeutic Trials!
‘Chemotherapy of Some Non—bacterial infections'
"Chemotherapy'
"Revision! (notes on therapeutic drugs)
"Drugs used in Psychiatry?
‘Oral hypoglycaemic compounds
124. tRadioactive Isotopes!
‘Thyroid and Antithyroid drugs!
"CHemotherapy of Malignant Disease?
"Infestation with worms?
*Gout'
"Pneumonia!
"Mode of Action of Arsenic"
"treatment of Parkinsonism!
‘Treatment of Common Symptoms?
"Mechanical Methods of removing fluid in Heart failure!
"Vasodilators and Hypotensive Drugs!
"Poisoning!
‘Dreatment of Cough!
‘Substances depressing Bone Marrow!
"Histamines, Antihistamines, Anaphylaxis, ATlergy'
Hormones of the Adrenal Cortex and Analogues!
‘Some enzymes used medicinally'
TIO?
447,
412.
113.
114.
115.
116,
137,
118.
119.
120.
a
122.
123.
123A.
"Salt and Water Balance!
"Treatment of Poisoning*
99-6
100.
101.
102,
103.
‘Iatrogenic diseases!
R.S.S. CSAC. 22/16/74
"Vitamin Deficiency'
‘Anaesthetics’
"Uses of Drugs which Act as Synapses'
"Disinfectants!
"Analgesics'
"Chemotherapy' (with note 'Replaced 1955")
'Post Pituitary Extract.!
'Potassium Deficiency'
‘Anaemia’ (with note on alternative lecturers)
"Coronary Thrombosis! (with note of alternative lecturer)
"Blood, Blood Products and Blood Substitutes!
‘Adrenal Cortex!
‘Hormones of the Anterior Pituitary Gland'
"Sex Hormones?
*Constipation'
"Therapeutics! — Mangement in General Practice
"Preparations and Uses.!
General lecture on drugs.
General introductory lecture and reading list for course on Therapeutics.
Applied Pharmacology and Therapeutics 1949 — 1961
Detailed plan of course year by year,with titles of lecture subjects,
names of lecturers etc.,plans for visits, related correspondence with
colleagues etc.
1949 = 61
Course in Pharmacology (later Applied Pharmacology and Therapeutics)
Syllabus,lecture courses,introductory talks on scope of course,
misc.enotes for lectures by Stacey.
1951— 70
‘Gen. Pharmacology I*
"Biological Assay'
"Morphine and other Opium Alkaloids!
"Analgesics and Antipyretics'
"Drugs depressing the C.N.S.!
"Drugs acting on C.N
STACEY, Reginald Stephen v2
Published: 20 November, 2023 Author: admin