DALY, Ivan De Burgh

DALY_IVAN_DE_BURGH

THE ROYAL SOCIETY THE ROYAL COMMISSION ON HISTORICAL MANUSCRIPT: Joint Committee on Scientific and Technological Records C8ac 39/3/76 CONTEMPORARY SCIENTIFIC ARCHIVES CENTRE Papers of PROFESSOR IVAN DE BURGH DALY, F.R.S. (1893 - 1974) Listed by Jeannine Alton Harriot Weiskittel Deposited in the Wellcome institute for the History of Medicine London 1976 I. de B. Daly csac 39/3/76 Description of the collection t The papers cover the years 1858 — 1974 and were received from Professor Michael de Burgh Daly, elder son of Ivan de Burgh Daly, who retains some biographical material. The collection consists primarily of Professor Daly's meticulous Professor Michael de Burgh records of experiments (see note on page 4). Daly also retains the original draft and related manuscripts, notes and correspondence of an unpublished monograph entitled ‘Intrinsic Lung Mechanisms’. Mie collection also includes one box of correspondence with (and biographical information regarding) several eminent physiologists. All items are manuscript unless otherwise indicated; titles in inverted commas are those which appear on the manuscripts. Summary of career b. 1893 Educated Rossall School ist Class Natural Science Tripos Part I, Gonville and Caius College, Cambridge M.B., St. Bartholomew's Hospital M.D. Assistant in Department of Physiology, University College London Lecturer in Experimental Physiology, University of Wales, Cardiff Professor of Physiology, University of Birmingham Professor of Physiology, University of Edinburgh Fellow of the Royal Society, Edinburgh Fellow of the Royal Society Director, Institute of Animal Physiology, Babraham, Cambridge Wellcome Trust Research Fellow, Oxford ; 1914 1918 1922 1919 — 23 1923 -— 27 1927 - 33 1933 — AT 1934 1943 1948 — 58 1958 — 62 A full list of the honours and awards received by Professor Daly may be found in the obituary notices in Item A.14. Contents of the handlist Items Page A. B. C. Biographical and correspondence Scientific notebooks and working papers A.1 — Aw14 B.e1 = B29 Index to the correspondents 2 3 9 ~ Tt. de B. Daly csac 39/3/76 2 A. Biographical and correspondence A.1 5 autograph letters from Professor William Sharpey to Sir Charles Lyell 1858 — 71 /A.2 4 autograph letters from Sir Edward Sharpey—Schafer to Daly 1934 — 35 A.3 A.4 A.5 A.6 A.7 A.8 A.9 Daly's correspondence with G.M. Sharpey-Schafer (Sir Edward's daughter) re controversy over Carleton's edition of Essentials of Histology and re the Schafer method of artificial respiration 1936, 1943 Press cuttings re life and career of Sir Edward Sharpey-Schafer: subscription by pupils and colleagues for presentation of portrait plaque (1922), report of 11th International Congress of Physiology chaired by Sir Edward (1923), conferment of title of Emeritus Professor by University of Edinburgh (1933), obituary notices (1935) 1922 ~ 35 Typescript copy of appreciation of Sharpey-Schafer with ms. note by Daly 'For General Council Report’. scription for commission of bust of Sharpey—Schafer. Announcement of sub— 1935 - 36 Summary of career of Sharpey-Schafer (2 typescript copies, 4 an— notated by Daly), 2 bibliographies (1 list includes all joint publications with collaborators) ned. Ms. notes (by Daly?) on addresses delivered by Sharpey-Schafer and subsequently published: opening of winter session of Medical Faculty of University College, London, 1885; Address in Fnysiology, ~ British Association 1895; Address to graduates, University of Edinburgh, 1902; PresidentialAddress to Edinburgh University Physiology Society, 1919. 1885 - 191 Daly's correspondence with Sir Charles Sherrington (12 autograph letters from Sir Charles; 1 ms. copy of letter by Daly) 1934 - 49 Daly's correspondence with Sir Henry Dale (2 typescript letters from Dale dated 8 June 1937 and 17 June 1939; carbon copies of Daly's letters of 14 and 22 June 1939.) 1937, 1939 A.10 Daly's correspondence with Dr. William Snow Miller A.11 Daly's correspondence with Charles Singer re interpretation of the writings of Galen and Erasistratus 1932 — 36 1942 — 43 A.12 Daly's correspondence with Dr. K.D. Keele re description by Leonardo da Vinci of bronchial arteries and copies of corréspon— dence with O.L. Richmond re Galen (for eventual use in Daly's monograph ‘Intrinsic Mechanisms of the Lung' -— unpublished) 1953 - 54, 1964 1933 A.13 Letter of thanks from Lord Horder A.14 Obituary notices for Professor Daly 1951 1974 I. de B. Daly CSAC 39/3/76 Be B. Scientific notebooks and working papers Professor Daly used the following abbreviations in his work: NPV IPL BP PAp H—L PLA LLP IIPL CSPR VCPLA ENB i@p PWA Negative Pressure Ventilation Isolated Perfused Lung Blood Pressure Pulmonary Arterial Pressure Heart-Lung Perfused Living Animal Left Lung Perfusion Innervated Isolated Perfused Lungs (also designated by IILP ~ Innervated Isolated Lung Perfusion) Carotid Sinus Pulmonary Resistance Vasosensory Controlled Perfused Living Animal Experimental Note—book Intrathoracic Pressure Perfused Whole Animal B.1 = B13 Large box file labelled on spine ‘EARLY WORK. Thermionic valves. NPV & ALLISON. BP zero' containing: B.1 B.2 B.3 B.4 BS. B.6 B.7 ‘With Shellshear. Originals. 1919's 2 pp. ms. draft, 12 pp. typescript with ms. annotations, drawings and photographs for accompanying figures String Galvanometer & Thermionic Valves. 1919 Work for closed circuit heart-lung paper: notes of experimental 1924 — 25 results, tabular summaries of data, graphs and charts, draft notes entitled 'Factors governing the redistribution of blood in the closed circuit heart—lung preparation.! Folder labelled *Pulmonary arteries. guide. cannula. survival dogs' containing photographs of dogs, graphs, equipment, cross=sections, X-rays. *tWork of Heart anil Constant Diastolic Volume': 2 pp. type— script with 2 pages of ms. tabular summaries of data. tThe effect of lowering the mean respiratory pressure on the output of the heart lung preparation’: 3pp. typescript n.d. 1925 'B ~ EE expts. 1930 — 1937's notes of experiments performed on animals, graphs and diagrams 1930 = 39 *The effect of drugs upon the lungs introduced through the bronchial arterial circulation': typescript with ms. annotations. © | ce 1934 Set of notes labelled "Unfinished! followed by list of contents. See file for details of contents. 1935 = 36 I. de B. Daly csac 39/3/76 B.8 B.9 B.10 B11 B.12 B.13 B.14 B15 4. 1937 — 38 1939 —- 40 1944 =— 45 ‘IPL. Pigs': notes and details of experiments 'Muscle Shadow Records's: notes of experiments *Cat and Dog expts.': notes and details of experiments, procedure and results Folder labelled "NPV. chamber — electrical connections. notes of experiments Oxford, 1960. Reverse of +” to -© 1960 Perspex chamber drawings": Folder labelled *Allison—Heath. containing notebooks with results of experiments, offprints, correspondence with and notes of P.R. Allison, correspondence with Donald Heath, Daly's notes Correspondence, records? (see also B.18) 1956 — 61 Folder labelled ‘Effect of BP zero on PAp, Pulm. in— and out- flow, and on respiration’ containing graphs, traces, tables, notes, plans for future experiments c.1950 Professor Daly kept detailed, step-by-step notes of his laboratory He included with this ‘raw experiments in large, loose-leaf notebooks. any diagrams, graphs, tracings, tabular summaries, photographs, data’ typescript summaries or other material which would provide a complete record of the experimental work in progress. B.17 and B.23, all of the following notebooks are of this description B.17 and B.23 are com and are listed as labelled by Professor Daly. pilations of material gathered over.a span of many years from a variety of sources; the handlist. the indexes to these bound volumes are given in full in With the exception of Be14 — B.16 are notebooks B,C, and D of a series on pulmonary circulation; notebook A is missing. Labelled on cover: 1926 = 30 'B. July 1926 to Jan. 1930" ‘Negative pressure IPL. Expts. with E.B. Verney. PAp, iOp, etc. & Drinker Injection of bronchial circulation.* oxygenator preparation. General pulm. circulation haemodynamics. Optical recording of Isolated heart S series expts. Closed circuit H-L preparation. Carotid sinus expts. Pulmonary circulation experiments. V —D, also 'C. JeLe Berry, AsS- Dale. V—D = Verney-Daly. 1933.! August 1928 to 1928 = 33 Labelled on cover: '1) First PLA expts. with E.B. Verney (see monograph by Catherine Hebb and self (1966) p.292.) 2) Upper-half of animal preparation. 3) Systematic — pulmonary circulation reflexes. 4) Head — Thorax (HT) preparations. August 1928 to 1933, assessments of experiments. te de B, Daly CSAC 39/3/76 : lg B. 16 B.17 'D. Pulmonary circulation experiments. with v. Euler and Thorpe. Isolated heart + oxygenator' 30.1.30 to Jan. 33. 1930 — 33 Bronchial + pulm. circ. perfusion. Labelled on covers tBronchial circulation and Pulmonary Circulation Perfusions. Injection expts. for X-ray Haemodynamics up to p.32. pp.50 — 65 Nerve stimulations pp.66 Jan. 6, 1931, first expt. with Ulf v. Euler — p.84. Summary of nerve stimulations p. 91. Closed circuit H-L preparations pp.36. Isolated heart + oxygenator (with Thorpe) Sinus carodicus expts. pp.5,7- Palmer Coil details — p.1.’ I. deBurgh Daly ‘Perfused Living Animal. 1936 — 47" : brown bound volume of notes taken during experiments, graphs, charts, photographs, tracings, descriptions of apparatus;with index as follows: ‘Pump scale outputs Dog 52 cm. snout to rump 6.75 kg. TA recorders. Air content of external respiratory circuit NPV, whole animal 0, cons. intact dog TA. of dog W.L.'s expts. 31,32,34-38,39,48,50,51 Brass cylinder S.I.P.L. 1936 — 47 Femoral cannulae data Raising and lowering third reservoir Oxygenator + isolated perfused lung P.L.A. 50 Thrombin Technique Trypan blue Summary Histology Einthovens intratracheal pressure method fitted to Ideal Starling Temp. recording Expt. 77 ¢ M. de B.D. " 81 ¢ Dr. Jalon, Madrid Filmed 774, 78, 79, 80 Ritchie stimulator now used "floating" see E.N.B. Perfusion of Left lung, 1 " » 2 wot tt Liquemin Roche used for first time in expt. 86 Effect of respiration on pulmonary blood flow' B.18 B.19 tAllisont : record of IIPL experiments 23,26,28,29,39,41, 52,53 carried out with P. Allison. copy of letter from Daly to P. Allison re IIPL expt. 53. (see also B.12). Notebook includes a 1951 — 57 ‘PLA LLP* : record of LLP experiments 1 — 25 (1947 — 54) and PLA experiments 90 - 104 (1951 = 54) 1947 — 54: 'M.deB.D./Waites' : LLP experiments 27 — 32 (1954) and IILP experiments 44 — 49 record of in SCPR series carried out with Michael deBurgh Daly VCPLA experiments 1 — 12 (January - July 1958) by I. and M. deBurgh Daly (with list of assistants) IIPL experiments 27, 30 — 32, 34 — 38, 42 — 43 (1956) with Includes typescript copy of report on G.M.H. Waites. IIPL experiment 43 sent to Sir Alan Drury, October 1956 Expts. 39 - 139. "Rats. record of experiments as labelled, . with notes and diagrams describing Borst technique 2 Borst expts. IIPL 54° : 6. 1954 - 58 1956 — 58 I. de B. Daly CsAc 39/3/76 B.20 B.21 B.22 B.23 "Histology : technical record, prints, calibrations of photographs taken during experiments in Series C, C, - Coy D . c.1963 — 66 'E.N.B.' 3: volume of photographs of apparatus,notes on others’ work (with illustrations and diagrams), offprints, graphs, notes on technique, preparations of solutions, tabular summaries of data, records of experiments, calibrations, notes on discussion, bibliography, correspondence, instructions for operation of equipment. ‘Air Ministry, bubble formation (discussion) With index as follows: 1939 = 50 " " n " = " chambers » explosive decompression » lungs (decompression) Aluminium tanks Anaesthesia, spinal Animal feeding Animal operation technique " i w CTAB Bellows manometers Animal rectal temperatures Barium sulphate technique Bellows, Brodie Bronchomotor nerves Belt dressing Calcium estimation Calorex glass (Chance) Cannulae pressure drop Cement, heatproof Cardiac nerves (Cunningham) Chance (calorex glass) Catheter (cardiac) details Chylomicrons, Frazer Distemper Drop recorders, Drugs, adr. bronchoconstr. Drugs, adr. (Burn) Prophylactics Diet (18 pellets) Electronic, Thorpe, Palmer 5 curare “ " w , curarine , general , PeLeA Electrical air pump (Dinton) " " " " " Cambridge thread recorder drop recorder st w ’ Bayli ss electrodes " (non—polarisable) I. de B. Daly CSAC 39/3/76 B.23 continued (Electrical) galv. constants " 7 7 . " 7 te " we " 7 " ® 7 " katharometers liquid resistances Palmer induction coil speedometer stimulator, Ashkenaz " wv " w » Ritchie ii} » exptl data P.L.A. » faradic », schmidt and Schmidt thermocouples thermometers thermoregulators Velodyne circuit welding transformer Weston relay Expansion, coefficients of, of metals Explosive decompression Fan motor Feeding of animals Flow recorder Pitot tubes ww " e i} t w » drop, Bayliss , Gaddum » thermo junction absorber Future experiments Galvanometer constants Gas, cadmium fumes Gas, CO Gas, CO, Gas drier Gas mixtures constants Gas, phosgene absorber Haemodynamics Heatproof cement Heparin _ Histology technique Home Office returns Injection masses Vinylite, Paraffin mass, barium sulphate " " " , starch I.P.L., action of drugs " " , blood volume changes technique Kymo paper fixing solution Larvae, lung Lung anatomy Lungs, biological constants Lung chemistry Lungs, decompression Lung larvae Manometer, closed end (Starling). Mayer pump Bellows manometers ‘ B. Daly I. de CSAC 39/3/76 B23 continued Nimmo-Smith Oxyhaemoglobin photometer P.L.A., action of drugs oxygenator » cleaning technique , drugs Heparin » evaluations and tests, also examples. » general details of apparatus. Cannulae (pressure drop) Current consumption Vertical Piston Recorders “ " 7 "pumps. " temperatures Piston recorders Pitot tubes, Pulmonary vasomotor nerves Phosgene Photographic. Plastics Ramage technique Ringer solutions Silicone Saja motor Starch granules Thermometers, electrical Thorpe drop recorder Vinylate Trowell fixing fluid * B.24 —~ B.29 Set of 6 notebooks in IIPL Series of experiments 1951 — 56. "ENB I. 1-— 50% : record of IIPL experiments 1 = 26, 33, 40, 50 with a note on the location of records for experiments 27 — 30, 34 = 39, 41 — 49 ‘ENB II. experiments 55 — 115 with DrB.A. Waaler 1958 —- 60. Expts. 55 to 115" : record of IIPL 1951 - 56 1958 — 60 "ENB III. autoperfusions! IPL 116 — 149 with Waaler 1958 - 61. Monkeys 1958 = 61 B.24 B.25 B.26 B.27 B.28 ‘ENB IV.' srecord of IPL and IIPL experiments 150 — 184 ‘ENB V. Dogs 185 — 240! Transmitter. 1962 to 1963 with C.B. Ferry. B.e29 ‘ENB VI. T(ransmitter) 243 to 258° 1961 — 62 1962 = 63 1964 = 65 I. de B. Daly CSAC’ 39/3/76 C. Index to the correspondents ALLISON, Professor P. Re BROWN, Sir George Lindor DALE, Sir Henry HEATH, Donald HORDER, Thomas Jeeves (Baron Horder of Ashford) KEELE, K. D. MILLER, William Snow RICHMOND, 0. L. RITCHIE, Anthony F. SHARPHY, Professor William SHARPEY-SCHAFER, Sir Edward SHARPEY-SCHAFER, G. M. SHERRINGTON, Sir Charles SINGER, Charlies B.12 B.23 Awd B.12 A.13 A.12 A.10 A.12 B.23 A.1 A.2 A.3 A.8 A.11